MCID: TRN044
MIFTS: 43

Transposition of the Great Arteries malady

Category: Rare diseases

Aliases & Classifications for Transposition of the Great Arteries

About this section

Aliases & Descriptions for Transposition of the Great Arteries:

Name: Transposition of the Great Arteries 45 24
Transposition of the Great Arteries, Dextro-Looped 1 65
Dextro-Looped Transposition of the Great Arteries 45
 
Dtga 45
Tga 45

Classifications:



External Ids:

UMLS65 C1837341

Summaries for Transposition of the Great Arteries

About this section
NIH Rare Diseases:45 Transposition of the great arteries (tga) is a type of congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. the aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body. symptoms are apparent at birth and include great difficulty breathing and severe cyanosis (a bluish discoloration of the skin). the exact cause of tga in most cases is unknown. surgery is done to correct the abnormality during the first few days of life. last updated: 6/27/2011

MalaCards based summary: Transposition of the Great Arteries, also known as transposition of the great arteries, dextro-looped 1, is related to transposition of the great arteries, dextro-looped 1 and congenitally corrected transposition of the great arteries. An important gene associated with Transposition of the Great Arteries is MED13L (Mediator Complex Subunit 13 Like), and among its related pathways are Heart Development and Developmental Biology. Affiliated tissues include heart, skin and lung, and related mouse phenotypes are respiratory system and muscle.

Related Diseases for Transposition of the Great Arteries

About this section

Diseases related to Transposition of the Great Arteries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 517)
idRelated DiseaseScoreTop Affiliating Genes
1transposition of the great arteries, dextro-looped 113.0
2congenitally corrected transposition of the great arteries13.0
3transposition of the great arteries, dextro-looped 212.9
4congenitally uncorrected transposition of the great arteries12.7
5isolated congenitally uncorrected transposition of the great arteries12.7
6congenitally uncorrected transposition of the great arteries with cardiac malformation12.7
7congenitally uncorrected transposition of the great arteries with coarctation12.7
8transposition of great arteries, dextro-looped 312.3
9conotruncal heart malformations12.0
10transient global amnesia11.7
11breast cancer10.7
12leukemia10.7
13arthritis10.6
14lymphoma10.6
15endotheliitis10.6
16aneurysm10.6
17melanoma10.5
18hypoxia10.5
19congenital heart defects, multiple types, 410.5
20heterotaxy, visceral, 6, autosomal recessive10.5
21heterotaxy, visceral, 1, x-linked10.5
22med13l syndrome10.5
23rheumatoid arthritis10.5
24lung cancer10.5
25hepatocellular carcinoma10.5
26adenocarcinoma10.5
27cerebritis10.5
28neuronitis10.5
29colorectal cancer10.5
30cystic fibrosis10.5
31hepatitis10.5
32esophagitis10.5
33ovarian cancer10.5
34pneumonia10.5
35influenza10.5
36systemic lupus erythematosus10.4
37multiple myeloma10.4
38gastric cancer10.4
39myeloma10.4
40chlamydia10.4
41dementia10.4
42cervicitis10.4
43ischemia10.4
44purpura10.4
45retinitis10.4
46tuberculosis10.4
47periodontitis10.4
48peritonitis10.4
49cholesteatoma10.4
50myeloid leukemia10.4

Graphical network of the top 20 diseases related to Transposition of the Great Arteries:



Diseases related to transposition of the great arteries

Symptoms for Transposition of the Great Arteries

About this section

Drugs & Therapeutics for Transposition of the Great Arteries

About this section

Drugs for Transposition of the Great Arteries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MechlorethamineapprovedPhase 430951-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
2
EplerenoneapprovedPhase 489107724-20-9150310, 443872
Synonyms:
107724-20-9
7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone
AC-4213
AC1L9FDC
C12512
CGP-30083
CHEBI:31547
CHEBI:726453
CHEMBL1095097
CID443872
D01115
Eplerenone
 
Eplerenone (JAN/USAN/INN)
Epoxymexrenone
Inspra
Inspra (TN)
Inspra, Epoxymexrenone, CGP30083, SC-66110,Eplerenone
MolPort-003-986-216
NCGC00159559-01
NCGC00159559-02
S1707_Selleck
SC-66110
Selara
TL8000270
ZINC03985982
3Mineralocorticoid Receptor AntagonistsPhase 4284
4MineralocorticoidsPhase 4301
5diureticsPhase 41194
6Natriuretic AgentsPhase 41403
7Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 49988
8Hormone AntagonistsPhase 410002
9HormonesPhase 411748
10Diuretics, Potassium SparingPhase 41445
11
AcetylcysteineapprovedPhase 2293616-91-112035
Synonyms:
(2R)-2-acetylamino-3-Sulfanylpropanoic acid
(R)-2-acetylamino-3-Mercaptopropanoic acid
(R)-Mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
 
Fluprowit
L-Acetylcysteine
L-alpha-acetamido-beta-Mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-ACETYL-L-cysteine
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
12
Epoetin alfaapprovedPhase 1, Phase 2626113427-24-0
Synonyms:
Epogen
 
Erythropoietin precursor
Procrit
13Respiratory System AgentsPhase 23931
14N-monoacetylcystinePhase 2293
15DextransPhase 272
16ExpectorantsPhase 2337
17Plasma SubstitutesPhase 2135
18Blood SubstitutesPhase 2148
19AnticoagulantsPhase 21760
20Pharmaceutical SolutionsPhase 27004
21Protective AgentsPhase 25651
22Phosphodiesterase InhibitorsPhase 21062
23Antiviral AgentsPhase 28071
24SimendanPhase 251
25Anti-Arrhythmia AgentsPhase 22371
26AntioxidantsPhase 22442
27Anti-Infective AgentsPhase 217220
28Vasodilator AgentsPhase 22926
29HematinicsPhase 1, Phase 21121
30
DexmedetomidineapprovedPhase 1470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
31Neurotransmitter AgentsPhase 114795
32Adrenergic AgentsPhase 14204
33Central Nervous System DepressantsPhase 110016
34Hypnotics and SedativesPhase 12032
35Peripheral Nervous System AgentsPhase 118510
36Adrenergic alpha-2 Receptor AgonistsPhase 1790
37Analgesics, Non-NarcoticPhase 15184
38Adrenergic alpha-AgonistsPhase 11300
39Adrenergic AgonistsPhase 12331
40AnalgesicsPhase 19358
41
Dobutamineapproved10834368-04-236811
Synonyms:
(+-)-4-(2-((3-(P-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
(+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
34368-04-2
34368-04-2 (Parent)
4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol
4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
4-{2-[3-(4-hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
52663-81-7 (hydrochloride)
74753-15-4
74753-15-4 (hydrobromide)
AC1L1WFF
AC1Q7AD1
BPBio1_000489
BRD-A78322124-003-03-3
BSPBio_000443
C06967
CHEBI:4670
CHEMBL926
CID36811
D03879
DB00841
DL-Dobutamine
DL-dobutamine
Dobutamin
Dobutamina
Dobutamina [INN-Spanish]
Dobutamine
Dobutamine (USP/INN)
Dobutamine Hcl
Dobutamine Hcl in Dextrose 5%
Dobutamine Hydrochloride
 
Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer
Dobutamine [USAN:BAN:INN]
Dobutamine [USAN]
Dobutamine [Usan:Ban:Inn]
Dobutamine [Usan]
Dobutamine hydrobromide
Dobutamine hydrochloride
Dobutaminum
Dobutaminum [INN-Latin]
Dobutrex
EINECS 277-982-4
HMS2089K05
Inotrex
L001157
LS-174467
LY 81929
Lilly 81929
Lopac0_000365
NCGC00015321-05
NCGC00024629-02
NCGC00024629-03
Prestwick0_000352
Prestwick1_000352
Prestwick2_000352
Prestwick3_000352
Racemic-Dobutamine
Racemic-dobutamine
SPBio_002364
UNII-0WR771DJXV
UNII-3S12J47372
dobutamine
dobutamine(usp)
rac-Dobutamine
rac-dobutamine
racemic-Dobutamine
42Adrenergic Antagonists1253
43Adrenergic beta-Antagonists979

Interventional clinical trials:

(show all 33)
idNameStatusNCT IDPhase
1Eplerenone in Systemic Right VentricleCompletedNCT00703352Phase 4
2The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart DiseaseTerminatedNCT01971593Phase 4
3Comparison of Hematocrit Levels in Infant Heart SurgeryCompletedNCT00006183Phase 3
4Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
5Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionNot yet recruitingNCT02744677Phase 3
6Levosimendan Administration in Neonates With Transposition of the Great ArteriesCompletedNCT01120106Phase 2
7N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study)CompletedNCT00374088Phase 2
8Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
9Erythropoetin Neuroprotection for Neonatal Cardiac SurgeryActive, not recruitingNCT00513240Phase 1, Phase 2
10A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsRecruitingNCT01915277Phase 1
11MRI Study After Arterial Switch Operation in Patients With Transposition of the Great ArteriesCompletedNCT01916499
12Effects of Beta-adrenergic in Adults w/Transposition of Great Arteries on Systemic Ventricular FunctionCompletedNCT00313352
13CT Coronary Angiography After Arterial Switch OperationCompletedNCT01153776
14Physical Training in Transposition of the Great ArteriesCompletedNCT00837603
15Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) FindingsCompletedNCT01430897
16Myocardial Contrast Echocardiography in Congenital Heart DiseaseCompletedNCT00412685
17Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
18Assessment of Left and Right Ventricular Function in Patients With Ebstein Anomaly With Different Echocardiographic MethodsCompletedNCT01907971
19Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental OutcomeCompletedNCT00713635
20A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal DefectCompletedNCT02361008
21Genes Causing Ebstein's AnomalyCompletedNCT00497705
22Fibrosis, Valvular and Ventricular Function in Patients With TGARecruitingNCT02588989
23Genetic Determinants of Congenital Heart Disease OutcomesRecruitingNCT01656941
24Cardiovascular MRI and Cardiopulmonary Exercise Capacity After Neonatal ASO) in Young AdultsRecruitingNCT02415491
25Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic ResonanceRecruitingNCT02161471
26Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)RecruitingNCT02184169
27T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart DiseaseRecruitingNCT02350829
28Quality of Life in Young Adults With Congenital Heart DiseaseRecruitingNCT02463292
29Comparative Assessment of Coronary MR Angiography Vs Coronary Multislice CT After Coronary Artery Reimplantation in Children and Young Adults.RecruitingNCT02542345
30Surgical Planning for Reconstruction of Complex Heart DefectsRecruitingNCT00972608
31National Congenital Heart Disease AuditRecruitingNCT02303535
32Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract ReconstructionNot yet recruitingNCT02700100
33Trial Comparing One-stage With Two-stage Basilic Vein TranspositionTerminatedNCT01274117

Search NIH Clinical Center for Transposition of the Great Arteries

Genetic Tests for Transposition of the Great Arteries

About this section

Anatomical Context for Transposition of the Great Arteries

About this section

MalaCards organs/tissues related to Transposition of the Great Arteries:

33
Heart, Skin, Lung, Breast, T cells, Brain, Bone

Animal Models for Transposition of the Great Arteries or affiliated genes

About this section

MGI Mouse Phenotypes related to Transposition of the Great Arteries:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4GATA6, GDF1, NKX2-5, NKX2-6, PITX2, TBX1
2MP:00053698.2GATA6, MED24, NKX2-5, NR2F2, PITX2, TBX1
3MP:00053808.0GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
4MP:00028738.0ANXA5, GATA6, GDF1, NKX2-5, NKX2-6, PITX2
5MP:00053847.9GATA6, GDF1, MED24, NKX2-5, NKX2-6, PITX2
6MP:00053977.7ANXA5, GATA6, GDF1, MED24, NKX2-5, PITX2
7MP:00053787.6GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
8MP:00107687.4GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
9MP:00053857.0GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2

Publications for Transposition of the Great Arteries

About this section

Articles related to Transposition of the Great Arteries:

(show top 50)    (show all 719)
idTitleAuthorsYear
1
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. (27001989)
2016
2
Viral co-infections in farmed Atlantic salmon, Salmo salar L., displaying myocarditis. (27146423)
2016
3
Stomatin-like protein 2 expression is associated with clinical survival in patients with cervical cancer. (25973071)
2015
4
Mixed Connective Tissue Disease and Papillary Thyroid Cancer: A Case Report. (26245523)
2015
5
Detecting O-GlcNAc using in vitro sulfation. (24799377)
2014
6
Ectodermal dysplasia associated with sickle cell disease. (25343049)
2014
7
Baseline elevated Lp-PLA2 is associated with increased risk for re-stenosis after stent placement. (24580749)
2014
8
Epstein-Barr virus negativity among individuals older than 60 years is associated with HLA-C and HLA-Bw4 variants and tonsillectomy. (23536655)
2013
9
Prediction of aphasia outcome using diffusion tensor tractography for arcuate fasciculus in stroke. (23042924)
2013
10
Regulatory role of miR-2909 in cell-mediated immune response. (22504889)
2012
11
Exercise training increases interleukin-10 after an acute myocardial infarction: a randomised clinical trial. (22187388)
2012
12
Analysis of synovial fluid in knee joint of osteoarthritis:5 proteome patterns of joint inflammation based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. (21509578)
2012
13
Juvenile Huntington disease in an 18-month-old boy revealed by global developmental delay and reduced cerebellar volume. (21412977)
2011
14
Oral manifestations as important symptoms for juvenile dermatomyositis early diagnosis: a case report. (20659183)
2011
15
A peptidoglycan monomer with the glutamine to serine change and basic peptides bind in silico to TLR-2 (403-455). (21188584)
2011
16
Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis. (20496422)
2010
17
The use of bioimpedance in the detection/screening of tongue cancer. (20097150)
2010
18
Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy. (19559397)
2009
19
Mental disorders as risk factors for later substance dependence: estimates of optimal prevention and treatment benefits. (19046473)
2009
20
Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. (19706884)
2009
21
Investigation on clinicopathologic features of lymphomatoid papulosis]. (20078970)
2009
22
Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis. (18710388)
2008
23
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. (17438529)
2007
24
Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. (17145766)
2007
25
Cytokine secretion profile associated with periportal fibrosis in S. mansoni-infected Egyptian patients. (17323139)
2007
26
ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. (16902247)
2006
27
Pharmacokinetics and pharmacodynamics of BIBT 986, a novel small molecule dual inhibitor of thrombin and factor Xa. (16839346)
2006
28
Combination of adenovirus p16(INK4A) gene therapy and ionizing radiation for laryngeal squamous cell carcinoma]. (15071918)
2004
29
Impaired spermatogenesis and genes]. (14968541)
2004
30
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. (15548201)
2004
31
The effect of genotype on the natural history of eIF2B-related leukodystrophies. (15136673)
2004
32
Evaluation of the degree of medical radiation damage with a highly sensitive chemiluminescence method. (15386798)
2004
33
Mutations in SEC63 cause autosomal dominant polycystic liver disease. (15133510)
2004
34
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. (11231638)
2001
35
Parameters involved in the recognition of fresh human leukemic blasts by tumor-specific cytolytic T cell clones: a model study. (10996200)
2000
36
VEGF, flt-1, and KDR/flk-1 as prognostic indicators in endometrial carcinoma. (10620438)
2000
37
Production and characterization of human monoclonal antibody Fab fragments to vaccinia virus from a phage-display combinatorial library. (10329580)
1999
38
Angiomatosis of skin with local intravascular immunoglobulin deposits, associated with monoclonal gammopathy. A potential cutaneous marker for B-chronic lymphocytic leukemia. A report of unusual case with immunohistochemical and immunofluorescence correlation and review of the literature. (10335899)
1999
39
Specific gene expression in pancreatic beta-cells: cloning and characterization of differentially expressed genes. (10078555)
1999
40
A DLST genotype associated with reduced risk for Alzheimer's disease. (10227647)
1999
41
A case of multicentric Castleman's disease associated with renal amyloidosis and pure red cell aplasia. (9627044)
1998
42
Regulation of [Ca2+]i rise activated by doxepin-sensitive H1-histamine receptors in Jurkat cells, cloned human T lymphocytes. (8919644)
1996
43
The enzyme activity of purine nucleotide degradation and lymphoid cell subpopulations in children with the Diamond-Blackfan syndrome]. (8020697)
1993
44
Evaluation of the efficacy and safety of oral tiludronate in Paget's disease of bone. A double-blind, multiple-dosage, placebo-controlled study. (1642662)
1992
45
Different cation transport inhibitor in benign and malignant experimental renal hypertension. (3794332)
1986
46
Terramycin in treatment of granuloma inguinale. (14825552)
1951
47
Pediatric case reports; bilateral parenchymal infiltration, consistent with a bronchopneumonia. (15415695)
1950
48
Remarks on a New Mode of Affording Permanent Relief to Intractable Chronic Cystitis, and to Confirmed Prostatic Retention of Urine. (20750395)
1882
49
50

Variations for Transposition of the Great Arteries

About this section

Expression for genes affiliated with Transposition of the Great Arteries

About this section
Search GEO for disease gene expression data for Transposition of the Great Arteries.

Pathways for genes affiliated with Transposition of the Great Arteries

About this section

Pathways related to Transposition of the Great Arteries according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2GATA6, NKX2-5, PITX2, TBX1
2
Show member pathways
8.6CFC1, GDF1, MED13L, MED24, NR2F2, ZIC3

GO Terms for genes affiliated with Transposition of the Great Arteries

About this section

Biological processes related to Transposition of the Great Arteries according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1atrial cardiac muscle cell developmentGO:005501410.6NKX2-5, NKX2-6
2thyroid gland developmentGO:003087810.4NKX2-5, TBX1
3embryonic heart tube developmentGO:003505010.4NKX2-5, NKX2-6
4blood vessel morphogenesisGO:004851410.4NR2F2, TBX1
5ventricular cardiac muscle cell developmentGO:005501510.4NKX2-6, PITX2
6pulmonary myocardium developmentGO:000335010.3NKX2-5, PITX2
7ventricular septum morphogenesisGO:006041210.3PITX2, ZFPM2
8vasculogenesisGO:000157010.3NKX2-5, ZFPM2
9cardiac muscle tissue developmentGO:004873810.2GATA6, NKX2-5, ZFPM2
10outflow tract septum morphogenesisGO:000314810.2GATA6, NKX2-5, TBX1
11anterior/posterior pattern specificationGO:000995210.1NR2F2, TBX1, ZIC3
12skeletal muscle tissue developmentGO:000751910.1NR2F2, PITX2
13pharyngeal system developmentGO:006003710.1NKX2-5, NKX2-6, TBX1
14cardiac muscle cell differentiationGO:005500710.0GATA6, NKX2-5, PITX2
15spleen developmentGO:004853610.0NKX2-5, PITX2
16determination of left/right symmetryGO:000736810.0PITX2, TBX1, ZIC3
17cell differentiationGO:00301549.8NKX2-5, NKX2-6, ZFPM2, ZIC3
18heart developmentGO:00075079.2NKX2-5, NKX2-6, PITX2, TBX1, ZFPM2
19transcription from RNA polymerase II promoterGO:00063669.2GATA6, MED24, NKX2-5, PITX2
20negative regulation of apoptotic processGO:00430669.1ANXA5, GATA6, NKX2-5, NKX2-6
21positive regulation of transcription from RNA polymerase II promoterGO:00459449.0NKX2-5, PITX2, TBX1, ZFPM2, ZIC3
22negative regulation of transcription from RNA polymerase II promoterGO:00001228.8GATA6, NKX2-5, NR2F2, PITX2, ZFPM2
23positive regulation of transcription, DNA-templatedGO:00458938.3GATA6, MED24, NKX2-5, NR2F2, PITX2, TBX1

Sources for Transposition of the Great Arteries

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet