MCID: TRN044
MIFTS: 46

Transposition of the Great Arteries malady

Category: Rare diseases

Aliases & Classifications for Transposition of the Great Arteries

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Aliases & Descriptions for Transposition of the Great Arteries:

Name: Transposition of the Great Arteries 45 24
Transposition of the Great Arteries, Dextro-Looped 1 65
Dextro-Looped Transposition of the Great Arteries 45
 
Dtga 45
Tga 45

Classifications:



External Ids:

UMLS65 C1837341

Summaries for Transposition of the Great Arteries

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NIH Rare Diseases:45 Transposition of the great arteries (tga) is a type of congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. the aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body. symptoms are apparent at birth and include great difficulty breathing and severe cyanosis (a bluish discoloration of the skin). the exact cause of tga in most cases is unknown. surgery is done to correct the abnormality during the first few days of life. last updated: 6/27/2011

MalaCards based summary: Transposition of the Great Arteries, also known as transposition of the great arteries, dextro-looped 1, is related to tricuspid valve disease and atrioventricular septal defect. An important gene associated with Transposition of the Great Arteries is MED13L (Mediator Complex Subunit 13 Like), and among its related pathways are Heart Development and Developmental Biology. Affiliated tissues include heart, skin and lung, and related mouse phenotypes are respiratory system and muscle.

Related Diseases for Transposition of the Great Arteries

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Diseases related to Transposition of the Great Arteries via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1tricuspid valve disease30.0CRELD1, NKX2-6
2atrioventricular septal defect30.0GATA6, NKX2-5, NKX2-6, PITX2
3congenital heart disease28.8CFC1, CRELD1, GATA6, NKX2-5, NKX2-6, TBX1
4congenitally corrected transposition of the great arteries12.7
5transposition of the great arteries, dextro-looped 112.6
6transposition of the great arteries, dextro-looped 212.5
7congenitally uncorrected transposition of the great arteries12.3
8isolated congenitally uncorrected transposition of the great arteries12.3
9congenitally uncorrected transposition of the great arteries with cardiac malformation12.3
10congenitally uncorrected transposition of the great arteries with coarctation12.3
11transposition of great arteries, dextro-looped 311.9
12conotruncal heart malformations11.6
13transient global amnesia11.5
14ventricular septal defect10.8
15left ventricular outflow tract obstruction10.6
16gerbode defect10.6NKX2-5, NKX2-6
17dextrocardia10.5
18punctate acrokeratoderma freckle like pigmentation10.5NR2F2, ZIC3
19situs inversus10.5
20diaphragm disease10.5NKX2-6, ZFPM2
21pulmonary hypertension10.4
22tricuspid atresia10.4
23univentricular heart with single atrio-ventricular valve10.4CRELD1, GATA6
24rhabdomyosarcoma of the corpus uteri10.4CFC1, GDF1, MED13L
25esophageal atresia10.3NR2F2, ZFPM2
26testicular trophoblastic tumor10.3CRELD1, ZIC3
27aortopulmonary window10.3
28joubert syndrome 1310.3NKX2-5, TBX1
29heart disease10.3
30aneurysm10.3
31campylobacteriosis10.3GATA6, NKX2-5, NKX2-6
32chromophobe adenoma10.3GATA6, NR2F2, ZFPM2
33beta-ureidopropionase deficiency10.3GDF1, NKX2-6, TBX1
34childhood central nervous system mature teratoma10.3CRELD1, NKX2-6
35dentinogenesis imperfecta, shields type ii10.2CRELD1, NKX2-6
36tetralogy of fallot10.2
37cor triatriatum10.2
38subpulmonary stenosis10.2
39horner's syndrome10.2NKX2-6, TBX1
40hypoplastic left heart syndrome10.2
41atrioventricular block10.2
42right aortic arch10.2
43hhv-6 encephalitis10.2CFAP53, CFC1, ZIC3
44congenital heart defects, multiple types, 410.1
45heterotaxy, visceral, 6, autosomal recessive10.1
46heterotaxy, visceral, 1, x-linked10.1
47med13l syndrome10.1
48neovascular glaucoma10.1CFC1, NKX2-5, ZIC3
49myocardial infarction10.1
50brain injury10.1

Graphical network of the top 20 diseases related to Transposition of the Great Arteries:



Diseases related to transposition of the great arteries

Symptoms for Transposition of the Great Arteries

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Drugs & Therapeutics for Transposition of the Great Arteries

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Drugs for Transposition of the Great Arteries (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MechlorethamineapprovedPhase 430951-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
2
EplerenoneapprovedPhase 489107724-20-9150310, 443872
Synonyms:
107724-20-9
7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone
AC-4213
AC1L9FDC
C12512
CGP-30083
CHEBI:31547
CHEBI:726453
CHEMBL1095097
CID443872
D01115
Eplerenone
 
Eplerenone (JAN/USAN/INN)
Epoxymexrenone
Inspra
Inspra (TN)
Inspra, Epoxymexrenone, CGP30083, SC-66110,Eplerenone
MolPort-003-986-216
NCGC00159559-01
NCGC00159559-02
S1707_Selleck
SC-66110
Selara
TL8000270
ZINC03985982
3Mineralocorticoid Receptor AntagonistsPhase 4284
4MineralocorticoidsPhase 4301
5diureticsPhase 41194
6Natriuretic AgentsPhase 41403
7Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 49988
8Hormone AntagonistsPhase 410002
9HormonesPhase 411748
10Diuretics, Potassium SparingPhase 41445
11
AcetylcysteineapprovedPhase 2293616-91-112035
Synonyms:
(2R)-2-acetylamino-3-Sulfanylpropanoic acid
(R)-2-acetylamino-3-Mercaptopropanoic acid
(R)-Mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
 
Fluprowit
L-Acetylcysteine
L-alpha-acetamido-beta-Mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-ACETYL-L-cysteine
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
12
Epoetin alfaapprovedPhase 1, Phase 2626113427-24-0
Synonyms:
Epogen
 
Erythropoietin precursor
Procrit
13Respiratory System AgentsPhase 23931
14N-monoacetylcystinePhase 2293
15DextransPhase 272
16ExpectorantsPhase 2337
17Plasma SubstitutesPhase 2135
18Blood SubstitutesPhase 2148
19AnticoagulantsPhase 21760
20Pharmaceutical SolutionsPhase 27004
21Protective AgentsPhase 25651
22Phosphodiesterase InhibitorsPhase 21062
23Antiviral AgentsPhase 28071
24SimendanPhase 251
25Anti-Arrhythmia AgentsPhase 22371
26AntioxidantsPhase 22442
27Anti-Infective AgentsPhase 217220
28Vasodilator AgentsPhase 22926
29HematinicsPhase 1, Phase 21121
30
DexmedetomidineapprovedPhase 1470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
31Neurotransmitter AgentsPhase 114795
32Adrenergic AgentsPhase 14204
33Central Nervous System DepressantsPhase 110016
34Hypnotics and SedativesPhase 12032
35Peripheral Nervous System AgentsPhase 118510
36Adrenergic alpha-2 Receptor AgonistsPhase 1790
37Analgesics, Non-NarcoticPhase 15184
38Adrenergic alpha-AgonistsPhase 11300
39Adrenergic AgonistsPhase 12331
40AnalgesicsPhase 19358
41
Dobutamineapproved10834368-04-236811
Synonyms:
(+-)-4-(2-((3-(P-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
(+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
34368-04-2
34368-04-2 (Parent)
4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol
4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
4-{2-[3-(4-hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
52663-81-7 (hydrochloride)
74753-15-4
74753-15-4 (hydrobromide)
AC1L1WFF
AC1Q7AD1
BPBio1_000489
BRD-A78322124-003-03-3
BSPBio_000443
C06967
CHEBI:4670
CHEMBL926
CID36811
D03879
DB00841
DL-Dobutamine
DL-dobutamine
Dobutamin
Dobutamina
Dobutamina [INN-Spanish]
Dobutamine
Dobutamine (USP/INN)
Dobutamine Hcl
Dobutamine Hcl in Dextrose 5%
Dobutamine Hydrochloride
 
Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer
Dobutamine [USAN:BAN:INN]
Dobutamine [USAN]
Dobutamine [Usan:Ban:Inn]
Dobutamine [Usan]
Dobutamine hydrobromide
Dobutamine hydrochloride
Dobutaminum
Dobutaminum [INN-Latin]
Dobutrex
EINECS 277-982-4
HMS2089K05
Inotrex
L001157
LS-174467
LY 81929
Lilly 81929
Lopac0_000365
NCGC00015321-05
NCGC00024629-02
NCGC00024629-03
Prestwick0_000352
Prestwick1_000352
Prestwick2_000352
Prestwick3_000352
Racemic-Dobutamine
Racemic-dobutamine
SPBio_002364
UNII-0WR771DJXV
UNII-3S12J47372
dobutamine
dobutamine(usp)
rac-Dobutamine
rac-dobutamine
racemic-Dobutamine
42Adrenergic Antagonists1253
43Adrenergic beta-Antagonists979

Interventional clinical trials:

(show all 33)
idNameStatusNCT IDPhase
1Eplerenone in Systemic Right VentricleCompletedNCT00703352Phase 4
2The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart DiseaseTerminatedNCT01971593Phase 4
3Comparison of Hematocrit Levels in Infant Heart SurgeryCompletedNCT00006183Phase 3
4Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
5Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionNot yet recruitingNCT02744677Phase 3
6Levosimendan Administration in Neonates With Transposition of the Great ArteriesCompletedNCT01120106Phase 2
7N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study)CompletedNCT00374088Phase 2
8Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
9Erythropoetin Neuroprotection for Neonatal Cardiac SurgeryActive, not recruitingNCT00513240Phase 1, Phase 2
10A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsRecruitingNCT01915277Phase 1
11MRI Study After Arterial Switch Operation in Patients With Transposition of the Great ArteriesCompletedNCT01916499
12Effects of Beta-adrenergic in Adults w/Transposition of Great Arteries on Systemic Ventricular FunctionCompletedNCT00313352
13CT Coronary Angiography After Arterial Switch OperationCompletedNCT01153776
14Physical Training in Transposition of the Great ArteriesCompletedNCT00837603
15Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) FindingsCompletedNCT01430897
16Myocardial Contrast Echocardiography in Congenital Heart DiseaseCompletedNCT00412685
17Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
18Assessment of Left and Right Ventricular Function in Patients With Ebstein Anomaly With Different Echocardiographic MethodsCompletedNCT01907971
19Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental OutcomeCompletedNCT00713635
20A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal DefectCompletedNCT02361008
21Genes Causing Ebstein's AnomalyCompletedNCT00497705
22Fibrosis, Valvular and Ventricular Function in Patients With TGARecruitingNCT02588989
23Genetic Determinants of Congenital Heart Disease OutcomesRecruitingNCT01656941
24Cardiovascular MRI and Cardiopulmonary Exercise Capacity After Neonatal ASO) in Young AdultsRecruitingNCT02415491
25Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic ResonanceRecruitingNCT02161471
26Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)RecruitingNCT02184169
27T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart DiseaseRecruitingNCT02350829
28Quality of Life in Young Adults With Congenital Heart DiseaseRecruitingNCT02463292
29Comparative Assessment of Coronary MR Angiography Vs Coronary Multislice CT After Coronary Artery Reimplantation in Children and Young Adults.RecruitingNCT02542345
30Surgical Planning for Reconstruction of Complex Heart DefectsRecruitingNCT00972608
31National Congenital Heart Disease AuditRecruitingNCT02303535
32Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract ReconstructionNot yet recruitingNCT02700100
33Trial Comparing One-stage With Two-stage Basilic Vein TranspositionTerminatedNCT01274117

Search NIH Clinical Center for Transposition of the Great Arteries

Genetic Tests for Transposition of the Great Arteries

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Anatomical Context for Transposition of the Great Arteries

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MalaCards organs/tissues related to Transposition of the Great Arteries:

33
Heart, Skin, Lung, Breast, Brain, Liver, Kidney

Animal Models for Transposition of the Great Arteries or affiliated genes

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MGI Mouse Phenotypes related to Transposition of the Great Arteries:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4GATA6, GDF1, NKX2-5, NKX2-6, PITX2, TBX1
2MP:00053698.2GATA6, MED24, NKX2-5, NR2F2, PITX2, TBX1
3MP:00053808.0GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
4MP:00028738.0ANXA5, GATA6, GDF1, NKX2-5, NKX2-6, PITX2
5MP:00053847.9GATA6, GDF1, MED24, NKX2-5, NKX2-6, PITX2
6MP:00053977.7ANXA5, GATA6, GDF1, MED24, NKX2-5, PITX2
7MP:00053787.6GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
8MP:00107687.4GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2
9MP:00053857.0GATA6, GDF1, MED24, NKX2-5, NKX2-6, NR2F2

Publications for Transposition of the Great Arteries

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Articles related to Transposition of the Great Arteries:

(show top 50)    (show all 749)
idTitleAuthorsYear
1
Current mid-term outcome with an integrated surgical strategy for correction of d-transposition of the great arteries with ventricular septal defect and left ventricular outflow tract obstruction. (27009103)
2016
2
Severe Pulmonary Vascular Obstructive Disease After Neonatal Arterial Switch Operation for Simple Transposition of the Great Arteries. (27098605)
2016
3
Criss-cross heart with dextrocardia and transposition of the great arteries: a rare pathology. (26875142)
2016
4
Atrial tachyarrhythmias after atrial switch operation for transposition of the great arteries: Treating old surgery with new catheters. (27018378)
2016
5
Palliative Arterial Switch for Congenitally Corrected Transposition of the Great Arteries with Ventricular Septal Defect and Subaortic Hypoplasia. (26498996)
2015
6
Anesthetic Considerations and Management of Transposition of the Great Arteries. (25900898)
2015
7
Juxtaposed right atrial appendage in complex Transposition of the Great Arteries. (25583626)
2015
8
Pulmonary Interstitial Glycogenosis: A Reversible Underlying Condition Associated With D-Transposition of the Great Arteries and Severe Persistent Pulmonary Hypertension. (26180171)
2015
9
Editorial comment: the use of veno-venous extracorporeal membrane oxygenation for perinatal support of an infant with d-transposition of the great arteries, intact atrial and ventricular septa, and flow-restricted ductus arteriosus. (25611995)
2014
10
Successful biventricular repair of double-outlet right ventricle with transposition of the great arteries, pulmonary stenosis, and straddling mitral valve. (24694423)
2014
11
Earlier Arterial Switch Operation Improves Outcomes and Reduces Costs for Neonates with Transposition of the Great Arteries. (24184243)
2013
12
The phenotypic spectrum of ZIC3 mutations includes isolated d-transposition of the great arteries and double outlet right ventricle. (23427188)
2013
13
Cardiac catheterisation of patients with common arterial trunk and transposition of the great arteries. (23331588)
2012
14
Autonomic nervous system function in infants with transposition of the great arteries. (21613339)
2012
15
Complete atrioventricular block in an adult with congenitally corrected transposition of the great arteries with interrupted inferior vena cava. (23798952)
2012
16
Atrioventricular node reentrant tachycardia in patients with congenitally corrected transposition of the great arteries and results of radiofrequency catheter ablation. (23159417)
2012
17
Long-term prognosis of double-switch operation for congenitally corrected transposition of the great arteries. (22551964)
2012
18
Percutaneous edge-to-edge repair of tricuspid regurgitation in congenitally corrected transposition of the great arteries. (21269414)
2011
19
Perioperative care of a child with transposition of the great arteries. (21706195)
2011
20
The modified Senning procedure as an integral part of an anatomical correction of congenitally corrected transposition of the great arteries. (24414198)
2011
21
Editorial comment Corrected transposition of the great arteries: is 'anatomic' repair the optimal option? (21515064)
2011
22
The role of the Fontan operation in the treatment of congenitally corrected transposition of the great arteries. (21976866)
2011
23
Long-term outcomes after an arterial switch operation for simple complete transposition of the great arteries. (20111649)
2010
24
Do predictors exist for a successful withdrawal of preoperative prostaglandin E(1) from neonates with d-transposition of the great arteries and intact ventricular septum? (20886209)
2010
25
The right ventricular response to high afterload: comparison between healthy persons and patients with transposition of the great arteries: a 2D strain study. (20618391)
2010
26
Congenitally corrected transposition of the great arteries presenting in a nonagenarian. (20805436)
2010
27
A case of platypnea-orthodeoxia syndrome caused by the interaction between the presence of corrected transposition of the great arteries and patent foramen ovale. (18706706)
2010
28
Congenitally corrected transposition of the great arteries plus dextrocardia operated with an unusual operative technique. (18704862)
2008
29
Enlarged bronchial collateral artery complicating recovery after arterial switch for simple transposition of the great arteries. (18757452)
2008
30
Intraoperative coronary artery pulse Doppler patterns in patients with complete transposition of the great arteries undergoing the arterial switch operation. (18760127)
2008
31
Cardiac defibrillation therapy for at risk patients with systemic right ventricular dysfunction secondary to atrial redirection surgery for dextro-transposition of the great arteries. (17383987)
2007
32
Metabolic alterations and neurodevelopmental outcome of infants with transposition of the great arteries. (16897317)
2006
33
That balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteries is another powerful argument in favor of therapeutic closure of every patent foramen ovale. (16828611)
2006
34
Primary surgical correction of transposition of the great arteries and atrioventricular septal defect associated with left isomerism. (16391973)
2006
35
A case of transposition of the great arteries in a female infant of a HIV-1-infected woman. Potential teratogenic effects of antiretroviral drugs. (16941823)
2006
36
Ablation of atrioventricular conduction in corrected transposition of the great arteries. (16648068)
2006
37
Successful repair of transposition of the great arteries with right aortic arch and coarctation of the aorta. (16482932)
2006
38
Relation between right ventricular structural alterations and markers of adverse clinical outcome in adults with systemic right ventricle and either congenital complete (after Senning operation) or congenitally corrected transposition of the great arteries. (17056346)
2006
39
Arterial switch operation for transposition of the great arteries combined with closure of paramembranous ventricular septal defect using the Amplatzer membranous ventricular septal occluder. (16098318)
2005
40
Late outcome of Senning and Mustard procedures for correction of transposition of the great arteries. (15831655)
2005
41
Repair of transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction. (15082275)
2004
42
Combined arterial switch and Senning operation for congenitally corrected transposition of the great arteries: patient selection and intermediate results. (12658191)
2003
43
Neurocutaneous melanosis with transposition of the great arteries and renal agenesis. (12869156)
2003
44
Congenitally corrected transposition of the great arteries in a 65-year-old woman. (11804307)
2001
45
Systemic ventricular inflow obstruction in congenitally corrected transposition of the great arteries. (9130433)
1997
46
Congenitally corrected transposition of the great arteries in the adult: functional status and complications. (8609349)
1996
47
Congenitally corrected transposition of the great arteries and exercise-induced ventricular tachycardia. (8640601)
1996
48
Tricuspid atresia with transposition of the great arteries in adolescents and adults: current state and late complications. (3342144)
1988
49
50

Variations for Transposition of the Great Arteries

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Expression for genes affiliated with Transposition of the Great Arteries

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Search GEO for disease gene expression data for Transposition of the Great Arteries.

Pathways for genes affiliated with Transposition of the Great Arteries

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Pathways related to Transposition of the Great Arteries according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2GATA6, NKX2-5, PITX2, TBX1
2
Show member pathways
8.6CFC1, GDF1, MED13L, MED24, NR2F2, ZIC3

GO Terms for genes affiliated with Transposition of the Great Arteries

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Biological processes related to Transposition of the Great Arteries according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1atrial cardiac muscle cell developmentGO:005501410.6NKX2-5, NKX2-6
2thyroid gland developmentGO:003087810.4NKX2-5, TBX1
3embryonic heart tube developmentGO:003505010.4NKX2-5, NKX2-6
4blood vessel morphogenesisGO:004851410.4NR2F2, TBX1
5ventricular cardiac muscle cell developmentGO:005501510.4NKX2-6, PITX2
6pulmonary myocardium developmentGO:000335010.3NKX2-5, PITX2
7ventricular septum morphogenesisGO:006041210.3PITX2, ZFPM2
8vasculogenesisGO:000157010.3NKX2-5, ZFPM2
9cardiac muscle tissue developmentGO:004873810.2GATA6, NKX2-5, ZFPM2
10outflow tract septum morphogenesisGO:000314810.2GATA6, NKX2-5, TBX1
11anterior/posterior pattern specificationGO:000995210.1NR2F2, TBX1, ZIC3
12skeletal muscle tissue developmentGO:000751910.1NR2F2, PITX2
13pharyngeal system developmentGO:006003710.1NKX2-5, NKX2-6, TBX1
14cardiac muscle cell differentiationGO:005500710.0GATA6, NKX2-5, PITX2
15spleen developmentGO:004853610.0NKX2-5, PITX2
16determination of left/right symmetryGO:000736810.0PITX2, TBX1, ZIC3
17cell differentiationGO:00301549.8NKX2-5, NKX2-6, ZFPM2, ZIC3
18heart developmentGO:00075079.2NKX2-5, NKX2-6, PITX2, TBX1, ZFPM2
19transcription from RNA polymerase II promoterGO:00063669.2GATA6, MED24, NKX2-5, PITX2
20negative regulation of apoptotic processGO:00430669.1ANXA5, GATA6, NKX2-5, NKX2-6
21positive regulation of transcription from RNA polymerase II promoterGO:00459449.0NKX2-5, PITX2, TBX1, ZFPM2, ZIC3
22negative regulation of transcription from RNA polymerase II promoterGO:00001228.8GATA6, NKX2-5, NR2F2, PITX2, ZFPM2
23positive regulation of transcription, DNA-templatedGO:00458938.3GATA6, MED24, NKX2-5, NR2F2, PITX2, TBX1

Sources for Transposition of the Great Arteries

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet