MCID: TRN003
MIFTS: 35

Transverse Colon Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Transverse Colon Cancer

MalaCards integrated aliases for Transverse Colon Cancer:

Name: Transverse Colon Cancer 12 14
Malignant Neoplasm of Transverse Colon 69
Malignant Tumor of Transverse Colon 12
Ca Transverse Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:261
ICD10 32 C18.4
ICD9CM 34 153.1
UMLS 69 C0153434

Summaries for Transverse Colon Cancer

MalaCards based summary : Transverse Colon Cancer, also known as malignant neoplasm of transverse colon, is related to mucinous adenocarcinoma and renal-hepatic-pancreatic dysplasia. An important gene associated with Transverse Colon Cancer is ETFA (Electron Transfer Flavoprotein Alpha Subunit), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Fluorouracil and Antimetabolites have been mentioned in the context of this disorder. Affiliated tissues include colon, lymph node and ovary.

Related Diseases for Transverse Colon Cancer

Diseases related to Transverse Colon Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 110)
# Related Disease Score Top Affiliating Genes
1 mucinous adenocarcinoma 29.4 KRT20 KRT7
2 renal-hepatic-pancreatic dysplasia 10.1 ETFA KRT7
3 subcorneal pustular dermatosis 10.0 DSC2 DSC3
4 paraneoplastic pemphigus 10.0 DSC2 DSC3
5 dowling-degos disease 10.0 DSC2 DSC3
6 cystic basal cell carcinoma 10.0 KRT20 KRT7
7 large cell carcinoma 10.0 DSC3 KRT7
8 lung acinar adenocarcinoma 10.0 KRT20 KRT7
9 vaginal benign neoplasm 10.0 KRT20 KRT7
10 seminal vesicle adenocarcinoma 10.0 KRT20 KRT7
11 ovarian large-cell neuroendocrine carcinoma 10.0 KRT20 KRT7
12 vaginal adenoma 10.0 KRT20 KRT7
13 vaginal tubulovillous adenoma 10.0 KRT20 KRT7
14 eyelid neoplasm 10.0 KRT20 KRT7
15 malignant syringoma 10.0 KRT20 KRT7
16 krukenberg carcinoma 10.0 KRT20 KRT7
17 large intestine adenocarcinoma 10.0 KRT20 KRT7
18 glandular cystitis 10.0 KRT20 KRT7
19 linitis plastica 10.0 KRT20 KRT7
20 small cell carcinoma of the bladder 10.0 KRT20 KRT7
21 adenoid squamous cell carcinoma 10.0 KRT20 KRT7
22 eccrine sweat gland neoplasm 10.0 KRT20 KRT7
23 mucinous bronchioloalveolar adenocarcinoma 10.0 KRT20 KRT7
24 vulval paget's disease 10.0 KRT20 KRT7
25 bladder adenocarcinoma 10.0 KRT20 KRT7
26 bile duct cystadenocarcinoma 10.0 KRT20 KRT7
27 intratubular embryonal carcinoma 10.0 KRT20 KRT7
28 ovarian mucinous adenocarcinoma 10.0 KRT20 KRT7
29 thymus adenocarcinoma 10.0 KRT20 KRT7
30 gastric diffuse adenocarcinoma 10.0 KRT20 KRT7
31 meibomian cyst 10.0 KRT20 KRT7
32 bladder lymphoma 10.0 KRT20 KRT7
33 vulva adenocarcinoma 10.0 KRT20 KRT7
34 papillary serous adenocarcinoma 9.9 KRT20 KRT7
35 jejunal adenocarcinoma 9.9 KRT20 KRT7
36 chronic cystitis 9.9 KRT20 KRT7
37 renal pelvis carcinoma 9.9 KRT20 KRT7
38 rectum adenocarcinoma 9.9 KRT20 KRT7
39 medulloepithelioma 9.9 KRT20 KRT7
40 glycogen-rich clear cell breast carcinoma 9.9 KRT20 KRT7
41 paget disease, extramammary 9.9 KRT20 KRT7
42 ampulla of vater neoplasm 9.9 KRT20 KRT7
43 appendix cancer 9.9 KRT20 KRT7
44 ampulla of vater adenocarcinoma 9.9 KRT20 KRT7
45 mucinous cystadenocarcinoma 9.9 KRT20 KRT7
46 biliary papillomatosis 9.9 KRT20 KRT7
47 lymphoepithelioma-like carcinoma 9.9 KRT20 KRT7
48 endocervical adenocarcinoma 9.9 KRT20 KRT7
49 dermoid cyst 9.9 KRT20 KRT7
50 infiltrative basal cell carcinoma 9.9 KRT20 KRT7

Comorbidity relations with Transverse Colon Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Ascending Colon Cancer
Cecal Benign Neoplasm Colorectal Cancer
Deficiency Anemia Intestinal Obstruction
Iron Deficiency Anemia Paralytic Ileus
Protein-Energy Malnutrition Rectosigmoid Junction Neoplasm

Graphical network of the top 20 diseases related to Transverse Colon Cancer:



Diseases related to Transverse Colon Cancer

Symptoms & Phenotypes for Transverse Colon Cancer

Drugs & Therapeutics for Transverse Colon Cancer

Drugs for Transverse Colon Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 3 51-21-8 3385
2 Antimetabolites Phase 3
3 Antimetabolites, Antineoplastic Phase 3
4 Immunosuppressive Agents Phase 3
5 Cola Nutraceutical Phase 3,Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intra-operative Chemotherapy With 5-FU for Colorectal Cancer Patients Receiving Curative Resection: Efficacy and Safety Active, not recruiting NCT01465451 Phase 3 intra-operative 5-FU chemotherapy
2 Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients Unknown status NCT01861691 Phase 2
3 Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON) Recruiting NCT03200834

Search NIH Clinical Center for Transverse Colon Cancer

Genetic Tests for Transverse Colon Cancer

Anatomical Context for Transverse Colon Cancer

MalaCards organs/tissues related to Transverse Colon Cancer:

38
Colon, Lymph Node, Ovary, Pancreas, Bone Marrow, Bone, Liver

Publications for Transverse Colon Cancer

Articles related to Transverse Colon Cancer:

(show top 50) (show all 51)
# Title Authors Year
1
Whether partial colectomy is oncologically safe for patients with transverse colon cancer: a large population-based study. ( 29190993 )
2017
2
Laparoscopic vs open approach for transverse colon cancer. A systematic review and meta-analysis of short and long term outcomes. ( 28344158 )
2017
3
Comparison of short-term outcomes between laparoscopic-assisted and open complete mesocolic excision (CME) for the treatment of transverse colon cancer. ( 28285536 )
2017
4
Laparoscopic Colectomy Versus Open Colectomy for Treatment of Transverse Colon Cancer: A Systematic Review and Meta-Analysis. ( 28355104 )
2017
5
A comparison of laparoscopic and open D3 lymphadenectomy for transverse colon cancer. ( 28879395 )
2017
6
Spontaneous regression of transverse colon cancer: a case report. ( 28488173 )
2017
7
Metastases of transverse colon cancer to bilateral ovaries (Krukenberg tumor) and the left breast: A case report. ( 28693131 )
2017
8
Laparoscopic complete mesocolic excision via combined medial and cranial approaches for transverse colon cancer. ( 27566603 )
2016
9
Delayed cecal perforation after successful colonic metal stenting in a patient with transverse colon cancer. ( 27059038 )
2016
10
Laparoscopic resection of transverse colon cancer at splenic flexure: technical aspects and results. ( 27015933 )
2016
11
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28206924 )
2016
12
Perforated Transverse Colon Cancer Presenting as an Incarcerated Inguinal Hernia. ( 28877795 )
2016
13
Laparoscopic Complete Mesocolic Excision versus Open Complete Mesocolic Excision for Transverse Colon Cancer: Long-Term Survival Results of a Prospective Single Centre Non-Randomized Study. ( 26734758 )
2016
14
Short- and long-term outcomes of laparoscopic surgery vs open surgery for transverse colon cancer: a retrospective multicenter study. ( 27143915 )
2016
15
Perioperative and short-term oncological outcomes of single-port surgery for transverse colon cancer. ( 27699489 )
2016
16
Pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from transverse colon cancer. ( 27182170 )
2016
17
Outcome of Laparoscopic Versus Open Resection for Transverse Colon Cancer. ( 26197767 )
2015
18
Bullous pemphigoid with IgG autoantibodies to BP180 C-terminal domain and desmocollin 3 associated with transverse colon cancer. ( 26693637 )
2015
19
Laparoscopic Surgery for Transverse Colon Cancer: Short- and Long-Term Outcomes in Comparison with Conventional Open Surgery. ( 26583447 )
2015
20
Initial experience of robotic versus laparoscopic colectomy for transverse colon cancer: a matched case-control study. ( 26452727 )
2015
21
Comparison of long-term follow up of laparoscopic versus open colectomy for transverse colon cancer. ( 26130871 )
2015
22
Robotic transverse colectomy for mid-transverse colon cancer: surgical techniques and oncologic outcomes. ( 26531113 )
2015
23
Hematochezia due to Caecal Angiodysplazia led to Diagnosis of a Transverse Colon Cancer in a Young Female Patient: Case Report and Literature Review. ( 26305206 )
2015
24
Transverse colon cancer occurring at a colostomy site 35 years after colostomy: a case report. ( 25943390 )
2015
25
Preoperative assessment of vascular anatomy by multidetector computed tomography before laparoscopic colectomy for transverse colon cancer: report of a case. ( 25692419 )
2015
26
Metastatic mucinous adenocarcinoma of the distal common bile duct, from transverse colon cancer presenting as obstructive jaundice. ( 26379735 )
2015
27
Laparoscopic colectomy for transverse colon cancer: comparative analysis of short- and long-term outcomes. ( 26629108 )
2015
28
Ten-millimeter advanced transverse colon cancer accompanied by a sessile serrated adenoma and/or polyp. ( 25892059 )
2015
29
Comparative study of oncologic outcomes for laparoscopic vs. open surgery in transverse colon cancer. ( 24761404 )
2014
30
Transverse colon cancer presenting as acute abdominal wall abscess. ( 24798363 )
2014
31
Gastrocolic fistula secondary to transverse colon cancer. ( 24717990 )
2014
32
Laparoscopic versus open resection for transverse colon cancer. ( 25303924 )
2014
33
Long-term outcomes of laparoscopic surgery for advanced transverse colon cancer. ( 24449001 )
2014
34
A Report of Disseminated Carcinomatosis of the Bone Marrow Originating from Transverse Colon Cancer Successfully Treated with Chemotherapy Using XELOX plus Bevacizumab. ( 25126072 )
2014
35
Laparoscopic colectomy for transverse colon cancer in an automated peritoneal dialysis patient: A case report. ( 23706995 )
2013
36
The transverse colon cancer with the reversed rotation of the midgut treated with single incision laparoscopic colectomy. ( 24426562 )
2013
37
Invasive adenocarcinoma arising from a mixed hyperplastic/adenomatous polyp and synchronous transverse colon cancer. ( 23984814 )
2013
38
Short- and long-term results of laparoscopic surgery for transverse colon cancer. ( 23934542 )
2013
39
A long adult intussusception secondary to transverse colon cancer. ( 23801849 )
2013
40
A new approach to laparoscopic lymph node excision in cases of transverse colon cancer. ( 22269292 )
2012
41
Laparoscopic resection of transverse colon cancer: long-term oncologic outcomes in 58 patients. ( 22690652 )
2012
42
Surgical resection of locally advanced primary transverse colon cancer--not a worse outcome in stage II tumor. ( 21279365 )
2011
43
Curative resection of transverse colon cancer via minilaparotomy. ( 21675613 )
2011
44
Short-term outcomes of laparoscopic colectomy for transverse colon cancer. ( 20224982 )
2010
45
Left paraduodenal hernia incidentally diagnosed during operation for transverse colon cancer. ( 20453424 )
2010
46
A comparative study on the short-term clinicopathologic outcomes of laparoscopic surgery versus conventional open surgery for transverse colon cancer. ( 19263150 )
2009
47
Hybrid hand-assisted colectomy for transverse colon cancer: a useful technique for non-expert laparoscopic surgeons. ( 19823906 )
2009
48
Surgical and pathological outcomes of laparoscopic surgery for transverse colon cancer. ( 18379794 )
2008
49
Successful simultaneous operation of concomitant early gastric cancer, transverse colon cancer, and a common iliac artery aneurysm. ( 10483757 )
1999
50
A case of transverse colon cancer secondarily involving the liver, duodenum, and pancreas. ( 8680119 )
1996

Variations for Transverse Colon Cancer

Expression for Transverse Colon Cancer

Search GEO for disease gene expression data for Transverse Colon Cancer.

Pathways for Transverse Colon Cancer

Pathways related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 DSC2 DSC3 KRT20 KRT7
2
Show member pathways
11.38 DSC2 DSC3 KRT20 KRT7

GO Terms for Transverse Colon Cancer

Cellular components related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.96 DSC2 DSC3
2 desmosome GO:0030057 8.62 DSC2 DSC3

Biological processes related to Transverse Colon Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 DSC2 DSC3 KRT20 KRT7
2 cornification GO:0070268 8.92 DSC2 DSC3 KRT20 KRT7

Sources for Transverse Colon Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....