MCID: TRM010
MIFTS: 52

Traumatic Brain Injury malady

Categories: Neuronal diseases

Aliases & Classifications for Traumatic Brain Injury

Aliases & Descriptions for Traumatic Brain Injury:

Name: Traumatic Brain Injury 38 51 41 3

Classifications:



Summaries for Traumatic Brain Injury

MedlinePlus : 41 traumatic brain injury (tbi) happens when a bump, blow, jolt, or other head injury causes damage to the brain. every year, millions of people in the u.s. suffer brain injuries. more than half are bad enough that people must go to the hospital. the worst injuries can lead to permanent brain damage or death. half of all tbis are from motor vehicle accidents. military personnel in combat zones are also at risk. symptoms of a tbi may not appear until days or weeks following the injury. a concussion is the mildest type. it can cause a headache or neck pain, nausea, ringing in the ears, dizziness, and tiredness. people with a moderate or severe tbi may have those, plus other symptoms: a headache that gets worse or does not go away repeated vomiting or nausea convulsions or seizures inability to awaken from sleep slurred speech weakness or numbness in the arms and legs dilated eye pupils health care professionals use a neurological exam and imaging tests to assess tbi. serious traumatic brain injuries need emergency treatment. treatment and outcome depend on how severe the injury is. tbi can cause a wide range of changes affecting thinking, sensation, language, or emotions. tbi can be associated with post-traumatic stress disorder. people with severe injuries usually need rehabilitation. nih: national institute of neurological disorders and stroke

MalaCards based summary : Traumatic Brain Injury is related to status epilepticus and choroiditis. An important gene associated with Traumatic Brain Injury is APOE (Apolipoprotein E), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Akt Signaling. The drugs Midazolam and Propofol have been mentioned in the context of this disorder. Affiliated tissues include Bone, brain and eye, and related phenotypes are Decreased viability with paclitaxel and behavior/neurological

CDC : 3 Get the facts, signs and symptoms, response, recovery, prevention

NINDS : 51 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Wikipedia : 71 Traumatic brain injury (TBI), also known as intracranial injury, occurs when an external force injures... more...

Related Diseases for Traumatic Brain Injury

Diseases related to Traumatic Brain Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 245)
id Related Disease Score Top Affiliating Genes
1 status epilepticus 29.7 AQP4 IL1B MBP
2 choroiditis 29.5 IL10 IL1B IL6
3 personality disorder 29.4 APOE BDNF COMT DRD2
4 complex regional pain syndrome 29.2 AQP4 IL10 IL1B MBP
5 moderate and severe traumatic brain injury 12.3
6 brain injury 11.6
7 head injury 11.5
8 shaken baby syndrome 11.2
9 pseudobulbar affect 11.2
10 persistent vegetative state 11.2
11 post-traumatic epilepsy 11.2
12 dysphagia 11.2
13 agnosia 11.2
14 swallowing disorders 11.2
15 apraxia 11.2
16 locked-in syndrome 11.0
17 prosopagnosia 10.9
18 dementia pugilistica 10.9
19 tremor 10.9
20 cerebritis 10.5
21 hypopituitarism 10.5
22 brain edema 10.4
23 neuronitis 10.4
24 intracranial hypertension 10.3
25 myelinoclastic diffuse sclerosis 10.3 GFAP S100B
26 maturity-onset diabetes of the young 10.3 COMT IL10
27 central nervous system hemangioma 10.2 GFAP MBP S100B
28 c-p angle neurinoma 10.2 GFAP MBP S100B
29 children's interstitial lung disease 10.2 GFAP MBP
30 idiopathic generalized epilepsy 10.2 BDNF CASP3 GFAP
31 persistent mullerian duct syndrome 10.2 IL10 MBP S100B
32 proximal symphalangism 10.2 IL10 MBP S100B
33 bronchial mucus gland adenoma 10.2 GFAP S100B
34 limb ischemia 10.2 APOE IGF1 IL6
35 skin glomus tumor 10.2 GFAP S100B UCHL1
36 oculomotor nerve paralysis 10.2 IL1B IL6
37 post-traumatic stress disorder 10.2
38 ichthyosis lamellar 2 10.2 APOE GFAP MBP
39 anus leiomyosarcoma 10.1 IL10 IL6 S100B
40 dysautonomia 10.1
41 neonatal hypoxic and ischemic brain injury 10.1 AQP4 IL10 IL6
42 childhood type dermatomyositis 10.1 APOE IL1B IL6
43 common peroneal nerve lesion 10.1 IL1B IL6
44 diabetic encephalopathy 10.1 APOE IGF1 IL6 S100B
45 hypoxia 10.1
46 childhood electroclinical syndrome 10.1 IL10 IL1B IL6
47 hypoparathyroidism-retardation-dysmorphism syndrome 10.1 IL10 IL1B IL6
48 diabetes insipidus 10.1
49 growth hormone deficiency 10.1
50 rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies 10.1 IL10 IL1B IL6

Graphical network of the top 20 diseases related to Traumatic Brain Injury:



Diseases related to Traumatic Brain Injury

Symptoms & Phenotypes for Traumatic Brain Injury

GenomeRNAi Phenotypes related to Traumatic Brain Injury according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with paclitaxel GR00179-A-1 8.92 CASP3 IGF1 IL10
2 Decreased viability with paclitaxel GR00179-A-2 8.92 IGF1

MGI Mouse Phenotypes related to Traumatic Brain Injury:

44 (show all 22)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.42 AQP4 BDNF CASP3 COMT DRD2 GFAP
2 cardiovascular system MP:0005385 10.41 APOE AQP4 CASP3 COMT DRD2 GFAP
3 homeostasis/metabolism MP:0005376 10.41 GFAP IGF1 IL10 IL1B IL6 MBP
4 growth/size/body region MP:0005378 10.38 BDNF CASP3 DRD2 GFAP IGF1 IL10
5 mortality/aging MP:0010768 10.34 APOE AQP4 BDNF CASP3 DRD2 GFAP
6 nervous system MP:0003631 10.33 DRD2 GFAP IGF1 IL10 IL1B IL6
7 cellular MP:0005384 10.29 GFAP IGF1 IL10 IL6 MBP SPTAN1
8 hematopoietic system MP:0005397 10.29 APOE AQP4 CASP3 COMT DRD2 IGF1
9 immune system MP:0005387 10.26 IL6 MBP APOE AQP4 CASP3 COMT
10 integument MP:0010771 10.25 APOE BDNF CASP3 DRD2 IGF1 IL10
11 digestive/alimentary MP:0005381 10.24 APOE AQP4 BDNF CASP3 DRD2 GFAP
12 endocrine/exocrine gland MP:0005379 10.23 BDNF CASP3 COMT DRD2 IGF1 IL10
13 muscle MP:0005369 10.08 APOE CASP3 DRD2 GFAP IGF1 IL10
14 normal MP:0002873 10.06 BDNF DRD2 GFAP IGF1 IL10 MBP
15 hearing/vestibular/ear MP:0005377 10.03 APOE AQP4 BDNF CASP3 IGF1 MBP
16 no phenotypic analysis MP:0003012 9.98 APOE AQP4 BDNF CASP3 DRD2 IL10
17 renal/urinary system MP:0005367 9.97 APOE AQP4 CASP3 COMT DRD2 IGF1
18 reproductive system MP:0005389 9.97 APOE BDNF CASP3 COMT DRD2 IGF1
19 respiratory system MP:0005388 9.96 BDNF CASP3 COMT DRD2 IGF1 IL10
20 skeleton MP:0005390 9.76 APOE CASP3 DRD2 IGF1 IL10 IL1B
21 vision/eye MP:0005391 9.28 APOE AQP4 BDNF CASP3 GFAP IL10
22 taste/olfaction MP:0005394 9.26 APOE BDNF CASP3 DRD2

Drugs & Therapeutics for Traumatic Brain Injury

Drugs for Traumatic Brain Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 467)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
2
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 2078-54-8 4943
3
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 69-65-8 453 6251
4
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2 57-27-2 5288826
5
Citalopram Approved Phase 4,Phase 2 59729-33-8 2771
6
Zinc Approved Phase 4 7440-66-6 32051 23994
7
Amantadine Approved Phase 4,Phase 2,Phase 3 768-94-5 2130
8
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
9
Benzocaine Approved Phase 4,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
10
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
11
Aspirin Approved, Vet_approved Phase 4,Phase 2 50-78-2 2244
12
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
13
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
14
Galantamine Approved Phase 4,Phase 2 357-70-0 9651 908828, 9651
15
Methylphenidate Approved, Investigational Phase 4,Phase 2 113-45-1 4158
16
Ethanol Approved Phase 4,Phase 3,Phase 2 64-17-5 702
17
Topiramate Approved Phase 4,Phase 2 97240-79-4 5284627
18
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2 57-41-0 1775
19
Sertraline Approved Phase 4,Phase 2,Phase 3 79617-96-2 68617
20
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
21
Heparin Approved, Investigational Phase 4,Phase 1 9005-49-6 772 46507594
22
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 1 99-66-1 3121
23
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
24
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
25
Norepinephrine Approved Phase 4,Phase 2,Phase 1 51-41-2 439260
26
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
27
Testosterone Approved, Investigational Phase 4,Phase 2 58-22-0 6013
28
Fosphenytoin Approved Phase 4 93390-81-9 56339
29 Piracetam Approved Phase 4,Phase 3,Phase 2 7491-74-9
30
Acetylcholine Approved Phase 4,Phase 3,Phase 2 51-84-3 187
31
Tizanidine Approved Phase 4,Phase 1 51322-75-9 5487
32
Dextromethorphan Approved Phase 4,Phase 3 125-71-3 5360696 5362449
33
Guaifenesin Approved, Vet_approved Phase 4 93-14-1 3516
34
Quinidine Approved Phase 4,Phase 2 56-54-2 441074
35
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 57-83-0 5994
36
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
37
Paroxetine Approved, Investigational Phase 4,Phase 2 61869-08-7 43815
38
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 1 525-66-6 4946
39
Oxytocin Approved, Vet_approved Phase 4,Phase 1 50-56-6 439302 53477758
40
Amitriptyline Approved Phase 4,Phase 2 50-48-6 2160
41
Memantine Approved, Investigational Phase 4 19982-08-2 4054
42
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 83-43-2 6741
43
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-24-8 5755
44
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
45
Dronabinol Approved, Illicit Phase 4,Phase 3,Phase 1 1972-08-3 16078 2978
46
Epinephrine Approved, Vet_approved Phase 4,Phase 3 51-43-4 5816
47
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3 50-23-7 5754 657311
48
Prazosin Approved Phase 4,Phase 1,Phase 2 19216-56-9 4893
49
Donepezil Approved Phase 4,Phase 3 120014-06-4 3152
50
Sumatriptan Approved, Investigational Phase 4,Phase 2 103628-46-2 5358

Interventional clinical trials:

(show top 50) (show all 1176)
id Name Status NCT ID Phase
1 A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function Unknown status NCT01712477 Phase 4
2 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4
3 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4
4 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4
5 Growth Hormone and Brain Functioning After Traumatic Brain Injury Unknown status NCT01699308 Phase 4
6 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4
7 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4
8 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4
9 Normoglycemia and Neurological Outcome Unknown status NCT01137773 Phase 4
10 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
11 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4
12 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4
13 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4
14 TXA in the EMS on the Helicopter and the Ambulance Unknown status NCT02354885 Phase 4
15 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4
16 Galantamine in the Treatment of Post-Traumatic Headache Unknown status NCT00219869 Phase 4
17 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4
18 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4
19 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4
20 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4
21 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4
22 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
23 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4
24 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4
25 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4
26 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4
27 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4
28 BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity Completed NCT00430196 Phase 4
29 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4
30 Enteral Glutamine in Neurologically-injured Patients Completed NCT00204971 Phase 4
31 Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient Completed NCT00163826 Phase 4
32 Does Oral Micronized Progesterone Shorten Time of Symptoms From Concussion Completed NCT01809639 Phase 4
33 NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit Completed NCT01685476 Phase 4
34 Group Cognitive Behavioral Therapy Versus Fluoxetine for Obsessive-Compulsive Disorder: a Practical Trial Completed NCT00680602 Phase 4
35 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4
36 Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure Completed NCT00447018 Phase 4
37 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4
38 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4
39 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4
40 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4
41 Treatments for Psychogenic Nonepileptic Seizures (NES) Completed NCT00159965 Phase 4
42 Treatment Trial for Psychogenic Nonepileptic Seizures Completed NCT00835627 Phase 4
43 Effect of Amantadine Administration on Spatial Functioning Following Traumatic Brain Injury Recruiting NCT02321761 Phase 4
44 Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits in Children Recruiting NCT02712996 Phase 4
45 Beta Blockade in in Traumatic Brain Injury Recruiting NCT02957331 Phase 4
46 Timing of VTE Prophylaxis in TBI Recruiting NCT03081169 Phase 4
47 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Recruiting NCT02404779 Phase 4
48 Prazosin for Post-Concussive Headaches Recruiting NCT02965027 Phase 4
49 Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion Recruiting NCT01824576 Phase 4
50 Efficiency of a Small-peptide Enteral Feeding Formula Compared to a Whole-protein Formula Recruiting NCT01833624 Phase 4

Search NIH Clinical Center for Traumatic Brain Injury

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Traumatic Brain Injury cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Traumatic Brain Injury:
MultiStem
Embryonic/Adult Cultured Cells Related to Traumatic Brain Injury:
Bone marrow-derived adherent progenitor cells (MultiStem) PMIDs: 23205020 20637752 23020860 21175285 21248119

Genetic Tests for Traumatic Brain Injury

Anatomical Context for Traumatic Brain Injury

MalaCards organs/tissues related to Traumatic Brain Injury:

39
Brain, Eye, Testes, Bone, Pituitary, Bone Marrow, Cortex
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Traumatic Brain Injury:
id Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate

Publications for Traumatic Brain Injury

Articles related to Traumatic Brain Injury:

(show top 50) (show all 1338)
id Title Authors Year
1
Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury. ( 28092022 )
2017
2
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
3
RANTES levels in peripheral blood, CSF and contused brain tissue as a marker for outcome in traumatic brain injury (TBI) patients. ( 28340601 )
2017
4
Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27812816 )
2017
5
Predictive validity of disability rating scale in determining functional outcome in patients with severe traumatic brain injury. ( 28084245 )
2017
6
Early neurological deterioration in older adults with traumatic brain injury. ( 28082072 )
2017
7
Childhood Traumatic Brain Injury and the Associations With Risk Behavior in Adolescence and Young Adulthood: A Systematic Review. ( 28092286 )
2017
8
Inflammation in epileptogenesis after traumatic brain injury. ( 28086980 )
2017
9
Outcome prediction in traumatic brain injury: Is it a "Holy Grail?" ( 28084246 )
2017
10
Long term neurobehavioral symptoms and return to productivity in Operation Enduring Freedom/Operation Iraqi Freedom Veterans with and without traumatic brain injury. ( 28088381 )
2017
11
Strategies of successful and unsuccessful simulators coached to feign traumatic brain injury. ( 28084893 )
2017
12
Cerebral amyloid angiopathy: a long-term consequence of traumatic brain injury? ( 27796651 )
2017
13
Reductions in Alexithymia and Emotion Dysregulation After Training Emotional Self-Awareness Following Traumatic Brain Injury: A Phase I Trial. ( 28060205 )
2017
14
Association of traumatic brain injury and Alzheimer disease onset: A systematic review. ( 28506441 )
2017
15
A Coordinated Action of Blood-Borne and Brain Insulin-Like Growth Factor I in the Response to Traumatic Brain Injury. ( 28449086 )
2017
16
Erratum to: Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27913939 )
2017
17
Startle suppression after mild traumatic brain injury is associated with an increase in pro-inflammatory cytokines, reactive gliosis and neuronal loss in the caudal pontine reticular nucleus. ( 28089558 )
2017
18
Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury. ( 28085565 )
2017
19
Protective Effects of Calpain Inhibition on Neurovascular Unit Injury through Downregulating Nuclear Factor-I_B-related Inflammation during Traumatic Brain Injury in Mice. ( 28091411 )
2017
20
Rapid neuroinflammatory response localized to injured neurons after diffuse traumatic brain injury in swine. ( 28081963 )
2017
21
The effect of concussion or mild traumatic brain injury on academic outcomes: A systematic review. ( 28084891 )
2017
22
Characteristics of Moderate and Severe Traumatic Brain Injury of Motorcycle Crashes in Bandung, Indonesia. ( 28087431 )
2017
23
Pediatric Traumatic Brain Injury: Families and Healthcare Team Interaction Trajectories During Acute Hospitalization. ( 28081932 )
2017
24
Does the cause of the mild traumatic brain injury affect the expectation of persistent postconcussion symptoms and psychological trauma? ( 27662262 )
2016
25
Sex-related Differences in Striatal Dopaminergic System after Traumatic Brain Injury. ( 27210290 )
2016
26
Increasing severity of traumatic brain injury in early childhood is associated with a progressive reduction in long-term serum thyroid-stimulating hormone concentrations. ( 26432979 )
2016
27
Traumatic Brain Injury Results in Cellular, Structural and Functional Changes Resembling Motor Neuron Disease. ( 27566977 )
2016
28
Apathy Due to Injury of the Prefrontocaudate Tract Following Mild Traumatic Brain Injury. ( 27661217 )
2016
29
Poster 365 Traumatic Brain Injury Resulting from Pontine and Extrapontine Myelinolysis due to Acute Onset of Pregnancy Induced Diabetes Insipidus: A Case Report. ( 27673118 )
2016
30
Efficiency of an Active Rehabilitation Intervention in a Slow-to-Recover Paediatric Population following Mild Traumatic Brain Injury: A Pilot Study. ( 28078321 )
2016
31
Patient-Specific Thresholds and Doses of Intracranial Hypertension in Severe Traumatic Brain Injury. ( 27165889 )
2016
32
Poster 321 Trazodone Associated Clitoral Priapism in a Transgender Man following Traumatic Brain Injury: A Case Report. ( 27673077 )
2016
33
Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co-morbid antidepressant- and anxiolytic-like potential using traumatic brain injury model in rats. ( 27662644 )
2016
34
Circulating MicroRNAs as Potential Biomarkers for Traumatic Brain Injury-Induced Hypopituitarism. ( 27027233 )
2016
35
Change of serum levels of thioredoxin in patients with severe traumatic brain injury. ( 26656445 )
2016
36
Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline. ( 27203137 )
2016
37
Plasma cytokines IL-6, IL-8, and IL-10 are associated with the development of acute respiratory distress syndrome in patients with severe traumatic brain injury. ( 27630085 )
2016
38
Mindful creativity matters: trajectories of reported functioning after severe traumatic brain injury as a function of mindful creativity in patients' relatives: a multilevel analysis. ( 27663903 )
2016
39
Neuroendocrine Disturbances One to Five or More Years after Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage: Data from the German Database on Hypopituitarism. ( 26914840 )
2016
40
Conscious status predicts mortality among patients with isolated traumatic brain injury in administrative data. ( 27663651 )
2016
41
Role of PiCCO monitoring for the integrated management of neurogenic pulmonary edema following traumatic brain injury: A case report and literature review. ( 27698733 )
2016
42
Righting Reflex Predicts Long-Term Histological and Behavioral Outcomes in a Closed Head Model of Traumatic Brain Injury. ( 27657499 )
2016
43
Prolonged hippocampal cell death following closed-head traumatic brain injury in rats. ( 27213933 )
2016
44
Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury. ( 27213280 )
2016
45
Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation. ( 27482224 )
2016
46
Moderate traumatic brain injury, acute phase course and deviations in physiological variables: an observational study. ( 27216804 )
2016
47
Heart rate variability and serum level of insulin-like growth factor-1 are correlated with symptoms of emotional disorders in patients suffering a mild traumatic brain injury. ( 26350409 )
2016
48
Screening for History of Traumatic Brain Injury among Women Exposed to Intimate Partner Violence. ( 27208397 )
2016
49
[BRAIN NATRIURETIC PEPTIDE AS A MARKER OF SEVERITY OF PATIENT'S CONDITION AFTER SEVERE TRAUMATIC BRAIN INJURY]. ( 27468499 )
2016
50
Growth hormone deficiency and hypopituitarism in adults after complicated mild traumatic brain injury. ( 27878771 )
2016

Variations for Traumatic Brain Injury

Expression for Traumatic Brain Injury

Search GEO for disease gene expression data for Traumatic Brain Injury.

Pathways for Traumatic Brain Injury

Pathways related to Traumatic Brain Injury according to GeneCards Suite gene sharing:

(show all 31)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.36 APOE BDNF CASP3 DRD2 IL1B IL6
2
Show member pathways
13.29 BDNF CASP3 IGF1 IL10 IL1B IL6
3
Show member pathways
13.18 AQP4 BDNF CASP3 IGF1 IL6 NGF
4
Show member pathways
13.14 BDNF CASP3 IGF1 IL10 IL1B IL6
5
Show member pathways
12.57 BDNF IGF1 IL1B IL6 NGF
6 12.21 APOE COMT GFAP MBP NGF S100B
7 12.1 CASP3 IL10 IL1B IL6
8 11.88 IL10 IL1B IL6
9 11.85 CASP3 IL1B IL6
10
Show member pathways
11.84 IL10 IL1B IL6
11 11.83 IGF1 IL1B IL6
12 11.78 CASP3 IL1B IL6
13 11.71 AQP4 BDNF CASP3 IL10 IL1B IL6
14