MCID: TRN004
MIFTS: 30

Trench Fever malady

Infectious, Bone categories

Summaries for Trench Fever

Sources:
8Disease Ontology, 3CDC, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A primary bacterial infectious disease that results in systemic infection, has material basis in bartonella quintana, which is transmitted by body lice (pediculus humanus corporis). the infection has symptom relapsing fever, has symptom headache, has symptom shin pain, and has symptom soreness of the muscles of the legs and back.

MalaCards: Trench Fever, also known as bartonellosis due to bartonella quintana infection, is related to q fever and typhus, and has symptoms including headache, relapsing fever and shin pain. An important gene associated with Trench Fever is DST (dystonin).

CDC:3 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Wikipedia:64 Trench fever (also known as \"Five day fever\", \"Quintan fever\" (febris Quintana in Latin), \"Urban... more...

Aliases & Classifications for Trench Fever

Sources:
8Disease Ontology, 10DISEASES, 49Orphanet, 61UMLS, 35MeSH, 27ICD9CM, 57SNOMED-CT, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 36MESH via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious
Anatomical: Bone


Aliases & Descriptions:

trench fever 8 10 49 61
bartonellosis due to bartonella quintana infection 49
his-werner disease 8
tibialgic fever 8
wolhynian fever 8
shin bone fever 8
quintan fever 8


External Ids:

Disease Ontology8 DOID:11101
MeSH35 D014205
ICD9CM27 083.1
ICD10 via Orphanet26 A79.0
SNOMED-CT57 82214002
SNOMED-CT via Orphanet58 82214002
UMLS via Orphanet62 C0040830
MESH via Orphanet36 D014205
ICD1025 A79.0

Related Diseases for Trench Fever

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Trench Fever via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1q fever10.7
2typhus10.4
3pediculus humanus corporis infestation10.1
4cat-scratch disease10.1
5carrion's disease10.1
6angiomatosis10.1
7nephritis10.1
8relapsing epidemic typhus10.1

Graphical network of diseases related to Trench Fever:



Diseases related to trench fever

Clinical Features for Trench Fever

Sources:
8Disease Ontology
See all sources


Symptoms:

8 (see all 4)
  • headache
  • relapsing fever
  • shin pain
  • soreness of the muscles of the legs

Drugs & Therapeutics for Trench Fever

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Trench Fever

Anatomical Context for Trench Fever

Animal Models for Trench Fever or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Trench Fever

Sources:
51PubMed
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Articles related to Trench Fever:

(show all 46)
idTitleAuthorsYear
1
Genetic diversity of Bartonella quintana in macaques suggests zoonotic origin of trench fever. (23517327)
2013
2
The Peacock versus the louse (pediculus humanus corporis): one soldier's contribution to combating trench fever in the First World War. (20973437)
2010
3
Urban trench fever presenting as culture-negative endocarditis. (18835881)
2009
4
High Bartonella spp. seroprevalence in a Swedish homeless population but no evidence of trench fever. (17852922)
2008
5
Trench fever: the British medical response in the Great War. (17082300)
2006
6
Detection of Bartonella quintana by direct immunofluorescence examination of blood smears of a patient with acute trench fever. (15472378)
2004
7
From trench fever to endocarditis. (14654579)
2003
8
Urban trench fever and cat scratch disease. (12684929)
2003
9
Urban trench fever in a healthy man from the southeastern United States. (12471587)
2002
10
Bartonella quintana and urban trench fever. (10913410)
2000
11
Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever. (10476755)
1999
12
Outbreak of epidemic typhus associated with trench fever in Burundi. (9717922)
1998
13
Trench fever among homeless people in Marseille, France: a seroprevalence survey. (9196653)
1997
14
The expanding spectrum of Bartonella infections: I. Bartonellosis and trench fever. (9002093)
1997
15
Bartonella species infections, including cat-scratch disease, trench fever, and bacillary angiomatosis--what molecular techniques have revealed. (8779201)
1996
16
Q fever and trench fever. (8727131)
1996
17
Has trench fever returned? (7529896)
1995
18
Return of trench fever. (7853966)
1995
19
Trench fever in Belfast, and the nature of the 'relapsing fevers' in the United Kingdom in the nineteenth century. (2672525)
1989
20
Trench fever. A resumAc of literature and a note on some obscure phases of the disease. (6432481)
1984
21
Antibiotic susceptibility patterns in Rochalimaea quintana, the agent of trench fever. (6742814)
1984
22
Enzyme immunoassay of antibody to Rochalimaea quintana: diagnosis of trench fever and serologic cross-reactions among other rickettsiae. (351072)
1978
23
Vole agent identified as a strain of the trench fever rickettsia, Rochalimaea quintana. (417026)
1978
24
A passive hemagglutination test for diagnosis of trench fever due to Rochalimaea quintana. (63526)
1976
25
Trench fever. II. Propagation of Rickettsia quintana on cell-free medium from the blood of two patients. (5810798)
1969
26
Trench fever. 3. Induction of clinical disease in volunteers inoculated with Rickettsia quintana propagated on blood agar. (5810799)
1969
27
Metabolic Activity of the Trench Fever Rickettsia, Rickettsia quintana. (16562152)
1967
28
In vitro cultivation of the rickettsial agent of trench fever. (5297000)
1966
29
Studies on trench fever. I. Propagation of Rickettsia-like microorganisms from a patient's blood. (13781520)
1961
30
Relapses in typhus and trench fever]. (13223218)
1954
31
Experimental infection of Macacus rhesus with Rickettsia quintana (trench fever). (13120859)
1953
32
Trench Fever. (20784435)
1942
33
Trench Fever: Final Report of the War Office Trench Fever Investigation Committee. (20474739)
1921
34
Trench Fever: Its Epidemiology and Endemiology. (19981284)
1920
35
PRELIMINARY REPORT ON THE PRESENCE OF A "FILTER PASSING" VIRUS IN CERTAIN DISEASES: With Especial Reference to Trench Fever, Influenza, and Nephritis. (20769352)
1919
36
The Association of Rickettsia with Trench Fever. (20474682)
1919
37
A CRITICISM OF CERTAIN RECENT CLAIMS TO HAVE DISCOVERED AND CULTIVATED THE FILTER-PASSING VIRUS OF TRENCH FEVER AND OF INFLUENZA. (20769587)
1919
38
TRENCH FEVER. (20769271)
1918
39
PRELIMINARY NOTE ON THE ASSOCIATION OF RICKETTSIA BODIES IN LICE WITH TRENCH FEVER. (20769186)
1918
40
ON THE ETIOLOGY OF TRENCH FEVER: (A Preliminary Communication.). (20768764)
1917
41
TRENCH FEVER AND ITS ALLIES. (20768629)
1917
42
NOTES ON SO-CALLED "TRENCH FEVER" AS SEEN IN ENGLAND. (20768481)
1917
43
A CASE OF "TRENCH FEVER," CONTRACTED IN ENGLAND. (20768479)
1917
44
Remarks ON "PYREXIA" OR "TRENCH FEVER.": Based upon Twelve Months' Experience with a Field Ambulance. (20768358)
1916
45
SOME NOTES ON TRENCH FEVER. (20768227)
1916
46
TRENCH FEVER: THE FIELD VOLE A POSSIBLE ORIGIN. (20768293)
1916

Genetic Variations for Trench Fever

Expression for genes affiliated with Trench Fever

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trench Fever

Search GEO for disease gene expression data for Trench Fever.

Pathways for genes affiliated with Trench Fever

Compounds for genes affiliated with Trench Fever

GO Terms for genes affiliated with Trench Fever

Sources:
16Gene Ontology
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Molecular functions related to Trench Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein C-terminus bindingGO:0080229.2DST, SYNJ2BP
2protein bindingGO:0055158.1TMEM11, DST, WDHD1, CCDC130

Products for genes affiliated with Trench Fever

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Trench Fever

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet