MCID: TRN004
MIFTS: 43

Trench Fever malady

Categories: Infectious diseases, Rare diseases, Bone diseases

Aliases & Classifications for Trench Fever

About this section
Sources:
10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 2CDC, 65UMLS, 27ICD10, 29ICD9CM, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Trench Fever:

Name: Trench Fever 10 12 51 36 2 65
Bartonellosis Due to Bartonella Quintana Infection 51
His-Werner Disease 10
Tibialgic Fever 10
 
Shin Bone Fever 10
Wolhynian Fever 10
Quintan Fever 10

Classifications:



External Ids:

Disease Ontology10 DOID:11101
ICD1027 A79.0
ICD9CM29 083.1
MeSH36 D014205
SNOMED-CT59 82214002
Orphanet51 64694
ICD10 via Orphanet28 A79.0
MESH via Orphanet37 D014205
UMLS via Orphanet66 C0040830
UMLS65 C0040830

Summaries for Trench Fever

About this section
Disease Ontology:10 A primary bacterial infectious disease that results in systemic infection, has material basis in Bartonella quintana, which is transmitted by body lice (Pediculus humanus corporis). The infection has symptom relapsing fever, has symptom headache, has symptom shin pain, and has symptom soreness of the muscles of the legs and back.

MalaCards based summary: Trench Fever, also known as bartonellosis due to bartonella quintana infection, is related to bartonellosis and cat-scratch disease, and has symptoms including relapsing fever, headache and shin pain. An important gene associated with Trench Fever is WARS (Tryptophanyl-TRNA Synthetase), and among its related pathways are MSP-RON Signaling and A-beta Pathways: Uptake and Degradation. Affiliated tissues include bone, prostate and breast.

CDC:2 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Wikipedia:68 Trench fever (also known as \"five-day fever\", \"quintan fever\" (febris quintana in Latin), and... more...

Related Diseases for Trench Fever

About this section

Diseases related to Trench Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idRelated DiseaseScoreTop Affiliating Genes
1bartonellosis26.9CCDC130, CD40LG, CXCL8, SYNJ2BP, TLR2, TLR4
2cat-scratch disease10.6
3lymph node cancer10.5TLR2, TLR4
4protein r deficiency10.5TLR2, TLR4
5exophthalmos10.5TLR2, TLR4
6anti-hla hyperimmunization10.5TLR2, TLR4
7basilar artery occlusion10.5TLR4, WARS
8angioid streaks of choroid10.5TLR2, TLR4
9neonatal adrenoleukodystrophy10.5TLR2, TLR4
10breast columnar cell mucinous carcinoma10.5TLR2, TLR4
11scleritis10.4CD40LG, TLR4
12ileocolitis10.4TLR2, TLR4
13myelocerebellar disorder10.4TLR2, TLR4
14invasive pneumococcal disease, recurrent isolated, 110.4TLR2, TLR4
15melioidosis10.4TLR2, TLR4
16keshan disease10.4TLR2, TLR4
17aniseikonia10.4CD40LG, TLR2
18vulvar melanoma10.4CD40LG, TLR2
19hair defect with photosensitivity and mental retardation10.4CXCL8, TLR2
20mycobacterium chelonae10.3CXCL8, TLR2
21tuberculous uveitis10.3CXCL8, TLR2
22acute gonococcal epididymo-orchitis10.3TLR2, TLR4
23scrotum squamous cell carcinoma10.3CXCL8, TLR4
24proliferative glomerulonephritis10.3CD40LG, CXCL8
25meningitis10.3TLR2, TLR4
26occipital lobe neoplasm10.3CXCL8, TLR2
27thrombocytopenia due to platelet alloimmunization10.3CD40LG, TLR2
28lateral sclerosis10.3CD40LG, TLR2
29osteochondrodysplasia10.3CD40LG, CXCL8
30jejunal cancer10.3CD40LG, CXCL8
31xanthogranulomatous pyelonephritis10.3CXCL8, TLR4
32funisitis10.2CXCL8, TLR4
33villonodular synovitis10.2CD40LG, CXCL8
34hard palate cancer10.2TLR2, TLR4
35deafness, autosomal recessive 6210.2TLR2, TLR4
36hypoglycemic coma10.2CXCL8, TLR4
37postcholecystectomy syndrome10.2CD40LG, CXCL8
38odontoclasia10.2CD40LG, TLR2
39typhus10.1
40relapsing fever10.1
41fat necrosis of breast10.1CXCL8, TLR2
42dentin dysplasia10.1CD40LG, CXCL8
43rumination disorder10.1CD40LG, TLR2, TLR4
44temporal arteritis10.1CD40LG, TLR2, TLR4
45social phobia10.1CD40LG, TLR2, TLR4
46trench fever10.1CD40LG, TLR2, TLR4
47interstitial emphysema10.1CD40LG, TLR2, TLR4
48common cold10.1CD40LG, TLR2, TLR4
49necatoriasis10.1CD40LG, TLR2, TLR4
50commensal bacterial infectious disease10.1CD40LG, TLR2, TLR4

Graphical network of the top 20 diseases related to Trench Fever:



Diseases related to trench fever

Symptoms for Trench Fever

About this section

Symptoms:

 10
  • relapsing fever
  • headache
  • shin pain
  • soreness of the muscles of the legs

Drugs & Therapeutics for Trench Fever

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Trench Fever


Cochrane evidence based reviews: trench fever

Genetic Tests for Trench Fever

About this section

Anatomical Context for Trench Fever

About this section

MalaCards organs/tissues related to Trench Fever:

33
Bone, Prostate, Breast, Tongue, Occipital lobe, Myeloid, B cells

Animal Models for Trench Fever or affiliated genes

About this section

Publications for Trench Fever

About this section

Articles related to Trench Fever:

(show all 48)
idTitleAuthorsYear
1
Correction: Competence of Cimex lectularius Bed Bugs for the Transmission of Bartonella quintana, the Agent of Trench Fever. (26075401)
2015
2
Competence of Cimex lectularius Bed Bugs for the Transmission of Bartonella quintana, the Agent of Trench Fever. (26000974)
2015
3
Trench fever: a relapsing fever occurring among the British troops in France and Salonica. (24845898)
2014
4
Genetic diversity of Bartonella quintana in macaques suggests zoonotic origin of trench fever. (23517327)
2013
5
The Peacock versus the louse (pediculus humanus corporis): one soldier's contribution to combating trench fever in the First World War. (20973437)
2010
6
Urban trench fever presenting as culture-negative endocarditis. (18835881)
2009
7
High Bartonella spp. seroprevalence in a Swedish homeless population but no evidence of trench fever. (17852922)
2008
8
Trench fever: the British medical response in the Great War. (17082300)
2006
9
Detection of Bartonella quintana by direct immunofluorescence examination of blood smears of a patient with acute trench fever. (15472378)
2004
10
From trench fever to endocarditis. (14654579)
2003
11
Urban trench fever and cat scratch disease. (12684929)
2003
12
Urban trench fever in a healthy man from the southeastern United States. (12471587)
2002
13
Bartonella quintana and urban trench fever. (10913410)
2000
14
Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever. (10476755)
1999
15
Outbreak of epidemic typhus associated with trench fever in Burundi. (9717922)
1998
16
Trench fever among homeless people in Marseille, France: a seroprevalence survey. (9196653)
1997
17
The expanding spectrum of Bartonella infections: I. Bartonellosis and trench fever. (9002093)
1997
18
Bartonella species infections, including cat-scratch disease, trench fever, and bacillary angiomatosis--what molecular techniques have revealed. (8779201)
1996
19
Q fever and trench fever. (8727131)
1996
20
Has trench fever returned? (7529896)
1995
21
Return of trench fever. (7853966)
1995
22
Trench fever in Belfast, and the nature of the 'relapsing fevers' in the United Kingdom in the nineteenth century. (2672525)
1989
23
Trench fever. A resumAc of literature and a note on some obscure phases of the disease. (6432481)
1984
24
Antibiotic susceptibility patterns in Rochalimaea quintana, the agent of trench fever. (6742814)
1984
25
Enzyme immunoassay of antibody to Rochalimaea quintana: diagnosis of trench fever and serologic cross-reactions among other rickettsiae. (351072)
1978
26
Vole agent identified as a strain of the trench fever rickettsia, Rochalimaea quintana. (417026)
1978
27
A passive hemagglutination test for diagnosis of trench fever due to Rochalimaea quintana. (63526)
1976
28
Trench fever. II. Propagation of Rickettsia quintana on cell-free medium from the blood of two patients. (5810798)
1969
29
Trench fever. 3. Induction of clinical disease in volunteers inoculated with Rickettsia quintana propagated on blood agar. (5810799)
1969
30
Metabolic Activity of the Trench Fever Rickettsia, Rickettsia quintana. (16562152)
1967
31
In vitro cultivation of the rickettsial agent of trench fever. (5297000)
1966
32
Studies on trench fever. I. Propagation of Rickettsia-like microorganisms from a patient's blood. (13781520)
1961
33
Relapses in typhus and trench fever]. (13223218)
1954
34
Experimental infection of Macacus rhesus with Rickettsia quintana (trench fever). (13120859)
1953
35
Trench Fever. (20784435)
1942
36
Trench Fever: Final Report of the War Office Trench Fever Investigation Committee. (20474739)
1921
37
Trench Fever: Its Epidemiology and Endemiology. (19981284)
1920
38
PRELIMINARY REPORT ON THE PRESENCE OF A "FILTER PASSING" VIRUS IN CERTAIN DISEASES: With Especial Reference to Trench Fever, Influenza, and Nephritis. (20769352)
1919
39
The Association of Rickettsia with Trench Fever. (20474682)
1919
40
A CRITICISM OF CERTAIN RECENT CLAIMS TO HAVE DISCOVERED AND CULTIVATED THE FILTER-PASSING VIRUS OF TRENCH FEVER AND OF INFLUENZA. (20769587)
1919
41
TRENCH FEVER. (20769271)
1918
42
PRELIMINARY NOTE ON THE ASSOCIATION OF RICKETTSIA BODIES IN LICE WITH TRENCH FEVER. (20769186)
1918
43
ON THE ETIOLOGY OF TRENCH FEVER: (A Preliminary Communication.). (20768764)
1917
44
TRENCH FEVER AND ITS ALLIES. (20768629)
1917
45
A CASE OF "TRENCH FEVER," CONTRACTED IN ENGLAND. (20768479)
1917
46
Remarks ON "PYREXIA" OR "TRENCH FEVER.": Based upon Twelve Months' Experience with a Field Ambulance. (20768358)
1916
47
SOME NOTES ON TRENCH FEVER. (20768227)
1916
48
TRENCH FEVER: THE FIELD VOLE A POSSIBLE ORIGIN. (20768293)
1916

Variations for Trench Fever

About this section

Expression for genes affiliated with Trench Fever

About this section
Search GEO for disease gene expression data for Trench Fever.

Pathways for genes affiliated with Trench Fever

About this section

GO Terms for genes affiliated with Trench Fever

About this section

Biological processes related to Trench Fever according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemokine productionGO:003272210.3TLR2, TLR4
2positive regulation of interferon-beta productionGO:003272810.3TLR2, TLR4
3positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.2TLR2, TLR4
4I-kappaB phosphorylationGO:000725210.2TLR2, TLR4
5positive regulation of interleukin-12 productionGO:003273510.2TLR2, TLR4
6positive regulation of tumor necrosis factor productionGO:003276010.1TLR2, TLR4
7toll-like receptor 4 signaling pathwayGO:003414210.1TLR2, TLR4
8positive regulation of interleukin-10 productionGO:003273310.0CD40LG, TLR4
9toll-like receptor TLR1:TLR2 signaling pathwayGO:00381239.9TLR2, TLR4
10MyD88-dependent toll-like receptor signaling pathwayGO:00027559.9TLR2, TLR4
11positive regulation of inflammatory responseGO:00507299.8TLR2, TLR4
12cellular response to lipoteichoic acidGO:00712239.8TLR2, TLR4
13lipopolysaccharide-mediated signaling pathwayGO:00316639.8TLR2, TLR4
14negative regulation of ERK1 and ERK2 cascadeGO:00703739.5SYNJ2BP, TLR4
15immune responseGO:00069558.9CXCL8, TLR2, TLR4

Sources for Trench Fever

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet