MCID: TRC003
MIFTS: 41

Trichomoniasis malady

Infectious diseases category
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Summaries for Trichomoniasis

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Sources:
8Disease Ontology, 34MedlinePlus, 4CDC, 65Wikipedia, 33MalaCards
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MedlinePlus:34 Trichomoniasis is a sexually transmitted disease caused by a parasite. you get it through sexual intercourse with an infected partner. many people do not have any symptoms. if you do get symptoms, they usually happen within 5 to 28 days after being infected. symptoms in women include yellow-green or gray discharge from the vagina discomfort during sex vaginal odor painful urination itching in or near the vagina most men do not have symptoms. if they do, they may have a whitish discharge from the penis and painful or difficult urination and ejaculation. lab tests can tell if you have the infection. treatment is with antibiotics. if you are infected, you and your partner must be treated. correct usage of latex condoms greatly reduces, but does not eliminate, the risk of catching or spreading trichomoniasis. nih: national institute of allergy and infectious diseases

MalaCards: Trichomoniasis, also known as trichomonas infections, is related to bacterial vaginosis and vaginitis. An important gene associated with Trichomoniasis is EXTL3 (exostosin-like glycosyltransferase 3). The compounds levamisole and zoledronic acid have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and skin.

Disease Ontology:8 A parasitic protozoa infectious disease that is caused by singled-celled protozoan parasites trichomonas vaginalis or trichomonas tenax, which infect the urogenital tract and mouth respectively.

CDC:4 Trichomoniasis is a very common STD that is easy to cure.

Wikipedia:65 Trichomoniasis, sometimes referred to as \"trich\", is a common cause of vaginitis. It is a sexually... more...

Aliases & Classifications for Trichomoniasis

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8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 62UMLS, 58SNOMED-CT, 35MeSH, 27ICD9CM, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

trichomoniasis 8 10 45 34
trichomonas infections 62


External Ids:

Disease Ontology8 DOID:1947
MeSH35 D014245
ICD9CM27 131, 131.9
NCIt40 C35720
ICD1025 A59, A59.9

Related Diseases for Trichomoniasis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Trichomoniasis:



Diseases related to trichomoniasis

Symptoms for Trichomoniasis

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Drugs & Therapeutics for Trichomoniasis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Trichomoniasis

Search NIH Clinical Center for Trichomoniasis

Genetic Tests for Trichomoniasis

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Anatomical Context for Trichomoniasis

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33MalaCards
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MalaCards organs/tissues related to Trichomoniasis:

33
Testes, Cervix, Skin, Colon, Breast, T cells

Animal Models for Trichomoniasis or affiliated genes

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Publications for Trichomoniasis

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52PubMed
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Articles related to Trichomoniasis:

(show top 50)    (show all 485)
idTitleAuthorsYear
1
Intravaginal metronidazole/miconazole for the treatment of vaginal trichomoniasis. (23949586)
2013
2
Trichomoniasis--an important cofactor of human immunodeficiency virus infection. (23745375)
2013
3
The role of immunity in the epidemiology of gonorrhoea, chlamydial infection and trichomoniasis: insights from a mathematical model. (21299913)
2011
4
A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy. (22047086)
2011
5
Mycoplasma hominis infection of Trichomonas vaginalis is not associated with metronidazole-resistant trichomoniasis in clinical isolates from the United States. (20652315)
2010
6
Respiratory tract trichomoniasis in breeder squab candidates in Northern California. (19432018)
2009
7
Lack of evidence for the involvement of rectal and oral trichomonads in the aetiology of vaginal trichomoniasis in Ghana. (16790560)
2007
8
Trichomoniasis: clinical manifestations, diagnosis and management. (15054166)
2004
9
Review: vaginal signs and symptoms perform poorly in diagnosing vaginal candidiasis, bacterial vaginosis, and vaginal trichomoniasis. (15341467)
2004
10
Detection of trichomoniasis in vaginal specimens by both conventional and modern molecular tools. (15287181)
2004
11
Addition of treatment for trichomoniasis to syndromic management of urethritis in Malawi: a randomized clinical trial. (12782954)
2003
12
Cost-effective screening for trichomoniasis. (12095452)
2002
13
A study on Trichomoniasis vaginalis and female infertility. (11478453)
2001
14
Interventions for trichomoniasis in pregnancy. (10796181)
2000
15
Trichomoniasis in a Bonelli's eagle population in Spain. (10682745)
2000
16
Rates of and risk factors for trichomoniasis among pregnant inmates in New York City. (9662764)
1998
17
Trichomoniasis in a postmenopausal woman cured after discontinuation of estrogen replacement therapy. (9339974)
1997
18
An incremental dosing protocol for women with severe vaginal trichomoniasis and adverse reaction to metronidazole. (8633672)
1996
19
Use of an animal model of trichomoniasis as a basis for understanding this disease in women. (8845444)
1995
20
Detection of bovine trichomoniasis with a specific DNA probe and PCR amplification system. (8126211)
1994
21
Split-dose metronidazole or single-dose tinidazole for the treatment of vaginal trichomoniasis. (1411848)
1992
22
A clinical evaluation of trichomoniasis in San Jose, Costa Rica using the InPouch TV test. (1427806)
1992
23
Trichomoniasis: trends in diagnosis and management. (1951578)
1991
24
Human amnion membrane as a model for studying the host-parasite relationship in trichomoniasis. (3265702)
1988
25
Vaginal secretory immunoglobulins and cell-mediated immune response in human trichomoniasis. (3373050)
1988
26
Epidemiologic and economic analyses of an unusually long epizootic of trichomoniasis in a large California dairy herd. (3771337)
1986
27
Bovine trichomoniasis. (3488101)
1986
28
Treatment of trichomoniasis with metronidazole rectal suppositories. (7104657)
1982
29
Combined systemic and topical treatment of trichomoniasis vaginalis with azanidazol. (7307267)
1981
30
Urinary trichomoniasis in Jeddah, Saudi Arabia. (7299174)
1981
31
Double blind comparative study of tinidazole and ornidazole as a single dose treatment of vaginal trichomoniasis. (7000949)
1980
32
Single-dose metronidazole treatment for vaginal trichomoniasis. (7422197)
1980
33
Trichomoniasis and other sexually transmitted diseases. (257246)
1979
34
Possibilities of rationalization in the treatment of trichomoniasis. (607577)
1977
35
Clinical evaluation of a single dose of tinidazole in trichomoniasis. (812644)
1975
36
Single-dose treatment of vaginal trichomoniasis with tinidazole. (4617665)
1974
37
2-day treatment of trichomoniasis with nimorazole. (4425934)
1974
38
Trichomonas vaginalis. II. Laboratory investigations in trichomoniasis. (4543452)
1973
39
Treatment of trichomoniasis in the female with a single dose of tinidazole. (4721041)
1973
40
Treatment of urogenital trichomoniasis. (4685516)
1973
41
Trichomoniasis. (4635620)
1972
42
Investigations on infectious infertility diseases in bovines, especially vibriosis and trichomoniasis, in India. (6010238)
1966
43
TRICHOMONIASIS IN EGYPT. 3. BACTERIOLOGICAL AND BIOCHEMICAL STUDIES OF THE VAGINAL DISCHARGE IN VAGINAL TRICHOMONIASIS. (14278217)
1965
44
OBSERVATIONS ON VAGINAL TRICHOMONIASIS. IV. SIGNIFICANCE OF VAGINAL FLORA UNDER VARIOUS CONDITIONS. (14268303)
1965
45
METRONIDAZOLE TREATMENT OF TRICHOMONIASIS IN PREGNANCY. (14268599)
1965
46
STUDIES ON METRONIDAZOLE (FLAGYL) IN THE THERAPY OF UROGENITAL TRICHOMONIASIS IN THE MALE PATIENT. (14260886)
1965
47
Trichomoniasis. Clinical trial of metronidazole (Flagyl). (13936092)
1963
48
Drugs for vaginal trichomoniasis: results of a comparative study. (14021502)
1962
49
An effective drug for trichomoniasis. (13890328)
1962
50
Observations on vaginal trichomoniasis. I. In pregnancy. (13742346)
1961

Variations for Trichomoniasis

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Expression for genes affiliated with Trichomoniasis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trichomoniasis

Search GEO for disease gene expression data for Trichomoniasis.

Pathways for genes affiliated with Trichomoniasis

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Compounds for genes affiliated with Trichomoniasis

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Sources:
45Novoseek, 11DrugBank, 61Tocris Bioscience, 24HMDB, 3BitterDB, 51PharmGKB
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Compounds related to Trichomoniasis according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1levamisole45 1110.6SLPI, IL2
2zoledronic acid459.6SLPI, IL2
3phosphorus459.5LAP3, SLPI
4ganciclovir45 1110.5SLPI, IL2
5succinate459.5SLPI, LAP3
6leukotriene b445 61 2411.4SLPI, LAP3
7azathioprine45 3 51 1112.3SLPI, IL2
8rantes459.3SLPI, IL2
9hydrocortisone45 3 61 1112.2IL2, SLPI
10calcitriol45 61 24 1112.0SLPI, IL2
11vegf458.9LAP3, IL2, SLPI

GO Terms for genes affiliated with Trichomoniasis

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16Gene Ontology
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Biological processes related to Trichomoniasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell growthGO:0303079.5EXTL3, IL2

Products for genes affiliated with Trichomoniasis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Trichomoniasis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet