MCID: TRC003
MIFTS: 37

Trichomoniasis malady

Infectious category

Summaries for Trichomoniasis

Sources:
8Disease Ontology, 34MedlinePlus, 3CDC, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Trichomoniasis is a sexually transmitted disease caused by a parasite. you get it through sexual intercourse with an infected partner. many people do not have any symptoms. if you do get symptoms, they usually happen within 5 to 28 days after being infected. symptoms in women include yellow-green or gray discharge from the vagina discomfort during sex vaginal odor painful urination itching in or near the vagina most men do not have symptoms. if they do, they may have a whitish discharge from the penis and painful or difficult urination and ejaculation. lab tests can tell if you have the infection. treatment is with antibiotics. if you are infected, you and your partner must be treated. correct usage of latex condoms greatly reduces, but does not eliminate, the risk of catching or spreading trichomoniasis. nih: national institute of allergy and infectious diseases

MalaCards: Trichomoniasis, also known as trichomonas infections, is related to bacterial vaginosis and vaginal discharge. An important gene associated with Trichomoniasis is FOXD3 (forkhead box D3). The compounds levamisole and zoledronic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, colon and breast.

Disease Ontology:8 A parasitic protozoa infectious disease that is caused by singled-celled protozoan parasites trichomonas vaginalis or trichomonas tenax, which infect the urogenital tract and mouth respectively.

CDC:3 Trichomoniasis is a common sexually transmitted disease (STD) that is easy to cure.

Wikipedia:64 Trichomoniasis, sometimes referred to as \"trich\", is a common cause of vaginitis. It is a sexually... more...

Aliases & Classifications for Trichomoniasis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 61UMLS, 35MeSH, 57SNOMED-CT, 27ICD9CM, 40NCIt, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

trichomoniasis 8 10 45 34
trichomonas infections 61


External Ids:

Disease Ontology8 DOID:1947
MeSH35 D014245
ICD9CM27 131, 131.9
NCIt40 C35720
ICD1025 A59, A59.9

Related Diseases for Trichomoniasis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Trichomoniasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1bacterial vaginosis30.8LAP3, SLPI
2vaginal discharge10.4
3gonorrhea10.3
4vaginal disease10.3
5vaginitis10.3
6campylobacteriosis10.2
7giardiasis10.2
8infertility10.2
9vulvovaginitis10.1
10dientamoebiasis10.1
11amebiasis10.1
12syphilis10.1
13viral hepatitis10.0SLPI
14hypercalcemia10.0SLPI
15human immunodeficiency virus infectious disease10.0EXTL3
16cork-handlers' disease10.0SLPI, IL2
17urethritis9.9
18cystic fibrosis9.9
19trachoma9.9
20cellulitis9.9
21vulvovaginal candidiasis9.9
22trypanosomiasis9.9
23mental retardation9.9

Graphical network of the top 20 diseases related to Trichomoniasis:



Diseases related to trichomoniasis

Clinical Features for Trichomoniasis

Drugs & Therapeutics for Trichomoniasis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Trichomoniasis

Drug clinical trials:

Search ClinicalTrials for Trichomoniasis

Search NIH Clinical Center for Trichomoniasis

Search CenterWatch for Trichomoniasis

Genetic Tests for Trichomoniasis

Anatomical Context for Trichomoniasis

Sources:
33MalaCards
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MalaCards organs/tissues related to Trichomoniasis:

33
Skin, Colon, Breast, Cervix, T cells, B cells

Animal Models for Trichomoniasis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Trichomoniasis

Sources:
51PubMed
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Articles related to Trichomoniasis:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Trichomoniasis--an important cofactor of human immunodeficiency virus infection. (23745375)
2013
2
Spatial and temporal epidemiology of bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina). (23518247)
2013
3
Performance of rapid immunochromatographic assay in the diagnosis of Trichomoniasis vaginalis. (22727836)
2012
4
Effect of trichomoniasis therapy on genital HIV viral burden among African women. (22797689)
2012
5
Resistant trichomoniasis: successful treatment with combination therapy. (21934573)
2011
6
Mycoplasma hominis infection of Trichomonas vaginalis is not associated with metronidazole-resistant trichomoniasis in clinical isolates from the United States. (20652315)
2010
7
Texas joins states with bovine trichomoniasis regulations: disease impairs fertility, reduces producer income. (19360996)
2009
8
Effect of Mexican medicinal plant used to treat trichomoniasis on Trichomonas vaginalis trophozoites. (17628366)
2007
9
The cost-effectiveness of treating male trichomoniasis to avert HIV transmission in men seeking sexually transmitted disease care in Malawi. (16951650)
2006
10
Kinetics of immunoglobulin G, M, A and IgG subclass responses in experimental intravaginal trichomoniasis: prominence of IgG1 response. (16255745)
2005
11
Diagnosis of trichomoniasis in 'virgin' bulls by culture and polymerase chain reaction. (14524627)
2003
12
Cost-effective screening for trichomoniasis. (12095452)
2002
13
Trichomonas vaginalis polymerase chain reaction compared with standard diagnostic and therapeutic protocols for detection and treatment of vaginal trichomoniasis. (12173132)
2002
14
Specific IgA response, T-cell subtype and cytokine profile in experimental intravaginal trichomoniasis. (11999021)
2002
15
A study on Trichomoniasis vaginalis and female infertility. (11478453)
2001
16
Diagnosis of trichomoniasis by polymerase chain reaction. (10198607)
1999
17
Recalcitrant vaginal trichomoniasis. (10448372)
1999
18
Sexually transmitted diseases in adolescents: focus on gonorrhea, chlamydia, and trichomoniasis--issues and treatment guidelines. (9832736)
1998
19
Study of trichomoniasis among Egyptian male patients. (9617063)
1998
20
Collaborative approach to improve the detection and management of trichomoniasis in a low prevalence district. (9530903)
1998
21
Prevalence and effects of trichomoniasis in pregnancy. (9707712)
1998
22
Evaluation of a murine model of experimental trichomoniasis. (9296057)
1997
23
A follow-up study of methods of contraception, sexual activity, and rates of trichomoniasis, candidiasis, and bacterial vaginosis. (2167008)
1990
24
N-nitrosamines, trichomoniasis and cervical cancer. (2928867)
1989
25
Trichomoniasis in free-living goshawks (Accipiter gentilis gentilis) from Great Britain. (3352101)
1988
26
The diagnosis of vaginal trichomoniasis. (3257533)
1988
27
Practical problems of diagnosing trichomoniasis in women. (3290090)
1988
28
Changes in the vaginal flora of trichomoniasis patients after vaccination with SolcoTrichovac. (6354887)
1983
29
Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. (657995)
1978
30
An evaluation of trichomoniasis in two ethnic groups in Papua New Guinea. (910202)
1977
31
Treatment of intestinal amoebiasis and vaginal trichomoniasis with panidazole and its comparison with metronidazole. (343312)
1977
32
Single-dose treatment of vaginal trichomoniasis with tinidazole. (4617665)
1974
33
Control of trichomoniasis in a large herd of beef cattle. (4447523)
1974
34
Treatment of trichomoniasis with a single oral dose of tinidazole ('Fasigyn'). (4407702)
1974
35
Trichomonas vaginalis. II. Laboratory investigations in trichomoniasis. (4543452)
1973
36
Screening for gonorrhoea, trichomoniasis, moniliasis and syphilis in pregnancy. (4633175)
1973
37
Dimetridazole, a systemic treatment for bovine venereal trichomoniasis. 3. Trials with cows. (5461095)
1970
38
Equine protozoan diarrhea (equine intestinal trichomoniasis) at Trinidad racetracks. (5812452)
1969
39
Chemotherapy of trichomoniasis. (4872132)
1968
40
The reproductive efficiency of several north Queensland beef herds. 2. The influence of vibriosis, trichomoniasis and lesions of the reproductive tract. (6067582)
1967
41
A clinical and laboratory study of trichomoniasis of the female genital tract. (5919105)
1966
42
Trichomoniasis in women. (5909914)
1966
43
METRONIDAZOLE IN THE TREATMENT OF VAGINAL TRICHOMONIASIS: HEMATOLOGIC, NEUROLOGIC, AND LONG-TERM CLINICAL EVALUATIONS. (14246946)
1965
44
Trichomoniasis. (5849932)
1965
45
Specific treatment of vaginal trichomoniasis--but when? (13954247)
1963
46
FURTHER STUDIES IN TREATMENT OF FEMALE AND MALE TRICHOMONIASIS WITH METRONIDAZOLE. (14065515)
1963
47
Trichomoniasis in a closed community: 100 per cent follow-up. (14454846)
1962
48
Combined systemic and topical therapy with metronidazole for vaginal trichomoniasis. (13706504)
1961
49
Differentiation between dead and living parasites in urogenital trichomoniasis, by means of a 1:1000 methylene blue solution. (13879620)
1961
50
Observations on vaginal trichomoniasis. II. Treatment with metronidazone. (14492945)
1961

Genetic Variations for Trichomoniasis

Expression for genes affiliated with Trichomoniasis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Trichomoniasis

Search GEO for disease gene expression data for Trichomoniasis.

Pathways for genes affiliated with Trichomoniasis

Compounds for genes affiliated with Trichomoniasis

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 2BitterDB, 60Tocris Bioscience, 24HMDB
See all sources

Compounds related to Trichomoniasis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1levamisole45 1110.6SLPI, IL2
2zoledronic acid459.6SLPI, IL2
3ganciclovir45 1110.5IL2, SLPI
4azathioprine45 50 2 1112.2SLPI, IL2
5phosphorus459.2LAP3, SLPI
6leukotriene b445 60 2411.1LAP3, SLPI
7succinate459.0LAP3, SLPI

GO Terms for genes affiliated with Trichomoniasis

Sources:
16Gene Ontology
See all sources

Biological processes related to Trichomoniasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell growthGO:0303079.6IL2, EXTL3

Products for genes affiliated with Trichomoniasis

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  • Proteins
  • Lysates
  • Antibodies

Sources for Trichomoniasis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet