Aliases & Classifications for Trichomoniasis

Aliases & Descriptions for Trichomoniasis:

Name: Trichomoniasis 12 52 41 3 14
Trichomonas Infections 42 69
Trichomonas Infection 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1947
ICD10 33 A59 A59.9
ICD9CM 35 131 131.9
MeSH 42 D014245
NCIt 47 C35720
UMLS 69 C0040921

Summaries for Trichomoniasis

MedlinePlus : 41 trichomoniasis is a sexually transmitted disease caused by a parasite. you get it through sexual intercourse with an infected partner. many people do not have any symptoms. if you do get symptoms, they usually happen within 5 to 28 days after being infected. it can cause vaginitis in women. symptoms include yellow-green or gray discharge from the vagina discomfort during sex vaginal odor painful urination itching in or near the vagina most men do not have symptoms. if they do, they may have a whitish discharge from the penis and painful or difficult urination and ejaculation. lab tests can tell if you have the infection. treatment is with antibiotics. if you are infected, you and your partner must be treated. correct usage of latex condoms greatly reduces, but does not eliminate, the risk of catching or spreading trichomoniasis. nih: national institute of allergy and infectious diseases

MalaCards based summary : Trichomoniasis, also known as trichomonas infections, is related to vulvovaginal candidiasis and syphilis, and has symptoms including fever, pelvic pain and pruritus. An important gene associated with Trichomoniasis is IL2 (Interleukin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Immune response IFN alpha/beta signaling pathway. The drugs Acetaminophen and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and t cells.

Disease Ontology : 12 A parasitic protozoa infectious disease that is caused by singled-celled protozoan parasites Trichomonas vaginalis or Trichomonas tenax, which infect the urogenital tract and mouth respectively.

CDC : 3 Women: trichomoniasis can cause problems with your pregnancy. Talk with your doctor about it.

Wikipedia : 71 Trichomoniasis (trich) is an infectious disease caused by the parasite Trichomonas vaginalis. About 70%... more...

Related Diseases for Trichomoniasis

Diseases related to Trichomoniasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
id Related Disease Score Top Affiliating Genes
1 vulvovaginal candidiasis 30.0 CD79A CXCL8
2 syphilis 30.0 CD79A EXTL3
3 filariasis 29.5 CD79A IRF6
4 vaginitis 11.6
5 dientamoebiasis 11.0
6 candidiasis 10.3
7 bacterial vaginosis 10.2
8 hemangioma of orbit 10.2 CD79A IL2
9 clostridium difficile colitis 10.2 CD79A IL2
10 barbiturate dependence 10.2 CD79A IL2
11 mild pre-eclampsia 10.2 CD79A EXTL3
12 muscular dystrophy 10.2 CD79A EXTL3
13 gonadal disease 10.2 CD79A IL2
14 venezuelan hemorrhagic fever 10.2 CD79A IL2
15 basilar artery occlusion 10.2 CD79A EXTL3
16 tularemia 10.2 CD79A IL2
17 dysplastic nevus syndrome 10.2 CD79A EXTL3
18 chromophobe adenoma 10.2 CXCL8 IL2
19 compensatory emphysema 10.2 CD79A EXTL3
20 central nervous system origin vertigo 10.2 CD79A IL2
21 thymic neuroendocrine carcinoma 10.2 CXCL8 IL2
22 inclusion conjunctivitis 10.2 CD79A IL2
23 labyrinthine bilateral reactive loss 10.2 CXCL8 IL2
24 squamous cell papilloma of skin 10.2 CD79A IL2
25 benjamin syndrome 10.2 CD79A EXTL3
26 amyotrophic lateral sclerosis type 14 10.2 CXCL8 IL2
27 pseudohypoparathyroidism 10.2 CD79A EXTL3
28 stomatitis 10.2 CXCL8 IL2
29 mesangial proliferative glomerulonephritis 10.2 CD79A CXCL8
30 ritscher-schinzel syndrome 1 10.2 CD79A CXCL8
31 newcastle disease 10.2 CD79A IL2
32 wilkes stevenson syndrome 10.1 CXCL8 IL2
33 multinodular goiter 10.1 CD79A IL2
34 omsk hemorrhagic fever 10.1 CD79A CXCL8
35 strawberry gallbladder 10.1 CXCL8 IL2
36 lateral cystocele 10.1 CD79A CXCL8
37 spinal cancer 10.1 CD79A IRF6
38 small intestine lymphoma 10.1 CD79A CXCL8
39 eye disease 10.1 CD79A IRF6
40 inappropriate adh syndrome 10.1 CXCL8 LAP3
41 ectothrix infectious disease 10.1 CD79A CXCL8
42 foodborne botulism 10.1 CD79A EXTL3 IL2
43 ovarian cystic teratoma 10.1 CD79A CXCL8
44 myiasis 10.1 CXCL8 IL2
45 actinic keratosis 10.1 CD79A IL2
46 plantar wart 10.1 CD79A CXCL8 IL2
47 nasopharyngitis 10.1 CD79A CXCL8 IL2
48 tracheitis 10.1 CD79A CXCL8 IL2
49 bone angioendothelial sarcoma 10.0 CD79A CXCL8 IL2
50 eyelid neoplasm 10.0 CD79A CXCL8

Comorbidity relations with Trichomoniasis via Phenotypic Disease Network (PDN):


Acute Cystitis Hypertension, Essential

Graphical network of the top 20 diseases related to Trichomoniasis:



Diseases related to Trichomoniasis

Symptoms & Phenotypes for Trichomoniasis

UMLS symptoms related to Trichomoniasis:


fever, pelvic pain, pruritus

Drugs & Therapeutics for Trichomoniasis

Drugs for Trichomoniasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 4 103-90-2 1983
2
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
3
Metronidazole Approved Phase 4,Phase 3,Phase 2,Early Phase 1 443-48-1 4173
4
Clindamycin Approved, Vet_approved Phase 4,Early Phase 1 18323-44-9 29029
5
Clotrimazole Approved, Vet_approved Phase 4,Phase 3 23593-75-1 2812
6 Anti-Bacterial Agents Phase 4,Phase 2,Early Phase 1
7 Antibiotics, Antitubercular Phase 4
8 Antidotes Phase 4
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
10 Antioxidants Phase 4
11 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
12 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
13 Antiviral Agents Phase 4
14 Expectorants Phase 4
15 N-monoacetylcystine Phase 4
16 Protective Agents Phase 4
17 Respiratory System Agents Phase 4
18 Clindamycin palmitate Phase 4,Early Phase 1
19 Clindamycin phosphate Phase 4,Early Phase 1
20 cysteine Nutraceutical Phase 4
21
Fluconazole Approved Phase 3,Early Phase 1 86386-73-4 3365
22
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Early Phase 1 22916-47-8 4189
23
Ethanol Approved Phase 3 64-17-5 702
24
Tinidazole Approved, Investigational Phase 3,Phase 2,Phase 1 19387-91-8 5479
25
Azithromycin Approved Phase 3,Phase 2 83905-01-5 55185 53477736 447043
26
Pyrimethamine Approved, Vet_approved Phase 3 58-14-0 4993
27
Sulfadoxine Approved Phase 3 2447-57-6 17134
28
Iron Approved Phase 3 7439-89-6 23925
29
chloroquine Approved, Vet_approved Phase 3 54-05-7 2719
30
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
31
leucovorin Approved, Nutraceutical Phase 3 58-05-9 54575, 6560146 143
32 Contraceptive Agents Phase 3
33 Antifungal Agents Phase 3,Phase 2,Early Phase 1
34 Cytochrome P-450 CYP2C9 Inhibitors Phase 3,Phase 2,Early Phase 1
35 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 2,Early Phase 1
36 Hormone Antagonists Phase 3,Phase 2,Early Phase 1
37 Hormones Phase 3,Phase 2,Early Phase 1
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Early Phase 1
39 Secnidazole Phase 3
40 Steroid Synthesis Inhibitors Phase 3,Phase 2,Early Phase 1
41 Alkylating Agents Phase 3,Phase 2,Phase 1
42 Antimalarials Phase 3,Phase 2
43 Fanasil, pyrimethamine drug combination Phase 3
44 Folic Acid Antagonists Phase 3
45 Renal Agents Phase 3
46 Vitamin B Complex Phase 3
47 Calcium, Dietary Phase 3
48 Micronutrients Phase 3
49 Trace Elements Phase 3
50 Analgesics Phase 3

Interventional clinical trials:

(show top 50) (show all 67)
id Name Status NCT ID Phase
1 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4
2 DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women Completed NCT01874158 Phase 4
3 Trichomonas Vaginalis Recurrence Among HIV+ Women Completed NCT01018095 Phase 4
4 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4
5 Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in Malawi Completed NCT00140764 Phase 3
6 Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission Completed NCT00213083 Phase 3
7 Effectiveness of a Community-level HIV/STD Prevention Intervention in Promoting Safer Sexual Behaviors in High-risk Populations Completed NCT00710060 Phase 3
8 Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge Completed NCT02111629 Phase 3
9 A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom Completed NCT01223313 Phase 3
10 Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments Completed NCT00313131 Phase 3
11 MEMA Kwa Vijana Trial: Impact of an Adolescent Sexual and Reproductive Health Intervention in Mwanza, Tanzania Completed NCT00248469 Phase 3
12 Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth Completed NCT00131235 Phase 3
13 Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS) Completed NCT01239693 Phase 3
14 Trichomonas Vaginalis Repeat Infections Among HIV Negative Women Recruiting NCT01832480 Phase 3
15 Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa Terminated NCT01103063 Phase 3
16 Effectiveness of the Diaphragm for HIV Prevention Withdrawn NCT00121459 Phase 3
17 Neo-Penotran Forte Vaginal Suppository for Vaginal Trichomoniasis Completed NCT01361048 Phase 2
18 Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women Completed NCT01230814 Phase 2
19 Study to Improve Partner Services for STD Prevention Completed NCT00207467 Phase 2
20 Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission Completed NCT00213018 Phase 2
21 Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide Completed NCT00213031 Phase 2
22 HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence Completed NCT01907126 Phase 2
23 Behavioral Intervention to Reduce Sexual and Injection Risks Among Female Sex Workers Who Also Inject Drugs in Mexico Completed NCT00840658 Phase 2
24 The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders Completed NCT01784809 Phase 2
25 HIV/STI Prevention for Drug-Involved Couples Completed NCT01285349 Phase 2
26 NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole) Completed NCT00322465 Phase 2
27 BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women Completed NCT00074425 Phase 2
28 Safer Sex Program for Young African-American Men Recruiting NCT01439503 Phase 2
29 Crossover Bioequivalence Study of Tinidazole 500 mg Tablets Under Fed Conditions Completed NCT01591889 Phase 1
30 Safety and Acceptability of Carraguard™ Among HIV-Negative Couples in Thailand Completed NCT00213057 Phase 1
31 S.T.A.R.S.: Sistas Talking About Real Solutions Completed NCT01028157 Phase 1
32 Accuracy and Acceptability of Self-Diagnostic Methods for Vaginitis in Adolescent Females Unknown status NCT00706368
33 Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays Unknown status NCT01728103
34 The Impact of Short-term Financial Incentives on Sexual Behavior and HIV Incidence in Lesotho Unknown status NCT01589965 Early Phase 1
35 The Contraceptive Choice Project Unknown status NCT01986439
36 Increased Access to Emergency Contraceptive Pills Unknown status NCT00060463
37 Female Urine, Vaginal & Endocervical Swab & Cervical Specimen Collections for APTIMA Trichomonas Vaginalis Assay Testing Completed NCT01427023
38 Control of Trichomoniasis Completed NCT00334555
39 A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue Test Completed NCT00682851
40 Cepheid Rectal Sample Validation Study Completed NCT02099760
41 Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis Completed NCT03178838
42 Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis Completed NCT02203942
43 Validity of Patient-Collected Wet Mounts Completed NCT02641717
44 Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy Testing Completed NCT00978848
45 Observational Program Neo-Penotran® Forte Completed NCT01335373
46 Rewarding Sexually Transmitted Infection (STI) Prevention and Control in Tanzania Completed NCT00922038
47 Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network Completed NCT00503542 Early Phase 1
48 Effectiveness of a Risk Reduction Program in Preventing the Transmission of HIV and Sexually Transmitted Diseases in African-American Couples Completed NCT00644163
49 Clinical Utility of Rapid CT/NG Testing in the ED Completed NCT02200224
50 Efficacy of HIV Post-Test Support for ANC in South Africa Completed NCT01683461

Search NIH Clinical Center for Trichomoniasis

Cochrane evidence based reviews: trichomonas infections

Genetic Tests for Trichomoniasis

Anatomical Context for Trichomoniasis

MalaCards organs/tissues related to Trichomoniasis:

39
Testes, Cervix, T Cells, Skin, Colon, Breast

Publications for Trichomoniasis

Articles related to Trichomoniasis:

(show top 50) (show all 527)
id Title Authors Year
1
A missed diagnosis of trichomoniasis. ( 28085787 )
2017
2
Antitrichomonal activity of Peganum harmala alkaloid extract against trichomoniasis in Pigeon (Columba livia domestica). ( 28084792 )
2017
3
Single-Dose Compared With Multidose Metronidazole for the Treatment of Trichomoniasis in Women: A Meta-Analysis. ( 27898571 )
2017
4
A Study on the Prevalence of Genital Trichomoniasis among Female Outpatients Attending Sexually Transmitted Infection Clinic in a Tertiary Care Hospital. ( 28042211 )
2017
5
Trichomoniasis in older individuals: a preliminary report from Iran. ( 27876991 )
2016
6
COMPARISON OF PERMANENT STAINING METHODS FOR THE LABORATORY DIAGNOSIS OF TRICHOMONIASIS. ( 26910452 )
2016
7
Rapid Antigen Testing for Trichomoniasis in an Emergency Department. ( 27207490 )
2016
8
A molecular-beacon-based asymmetric PCR assay for easy visualization of amplicons in the diagnosis of trichomoniasis. ( 27318568 )
2016
9
Epidemiology of Trichomoniasis in South Korea and Increasing Trend in Incidence, Health Insurance Review and Assessment 2009-2014. ( 27936227 )
2016
10
Comparative analysis of syndromic and PCR-based diagnostic assay reveals misdiagnosis/ overtreatment for trichomoniasis based on subjective judgment in symptomatic patients. ( 27146362 )
2016
11
A review of sexually transmitted bovine trichomoniasis and campylobacteriosis affecting cattle reproductive health. ( 26679515 )
2016
12
Prevalence of Trichomoniasis by PCR in Women Attending Health Screening in Korea. ( 27180577 )
2016
13
First report of an outbreak trichomoniasis in turkey in Sistan, Iran. ( 27065599 )
2016
14
Prevalence of asymptomatic infections in sexually transmitted diseases attendees diagnosed with bacterial vaginosis, vaginal candidiasis, and trichomoniasis. ( 27890946 )
2016
15
Challenges and persistent questions in treatment of trichomoniasis. ( 27697044 )
2016
16
Diagnosis of trichomoniasis in men by urine cytology. ( 27636204 )
2016
17
Trichomoniasis immunity and the involvement of the purinergic signaling. ( 27793265 )
2016
18
Trichomoniasis: a brief review of diagnostic methods and our experience with real-time PCR for detecting infection. ( 25770306 )
2015
19
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. ( 26001874 )
2015
20
Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age. ( 26266260 )
2015
21
A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections. ( 26602621 )
2015
22
Epidemiology and treatment of trichomoniasis. ( 25925796 )
2015
23
Prevalence of trichomoniasis among women in kermanshah, iran. ( 26019904 )
2015
24
Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review. ( 26424377 )
2015
25
A Diagnostic and Symptomatological Study on Trichomoniasis in Symptomatic Pregnant Women in Rafsanjan, South Central Iran in 2012-13. ( 26622305 )
2015
26
Comparison between mixed lysate antigen and I+-actinin antigen in ELISA for serodiagnosis of trichomoniasis. ( 26072305 )
2015
27
Trichomoniasis: Is it always sexually transmitted? ( 26396458 )
2014
28
Neglected parasitic infections in the United States: trichomoniasis. ( 24808247 )
2014
29
Epidemiology of undiagnosed trichomoniasis in a probability sample of urban young adults. ( 24626058 )
2014
30
Counterpoint: Screening for Trichomoniasis--Where's the Evidence of Benefit? ( 24043492 )
2014
31
Graphene and carbon nanotube composite enabling a new prospective treatment for trichomoniasis disease. ( 24907738 )
2014
32
Culture and immunochromatographic technique for diagnosis of trichomoniasis. ( 24682201 )
2014
33
Could point-of-care testing be effective for reducing the prevalence of trichomoniasis in remote Aboriginal communities? ( 25141073 )
2014
34
Risk factors associated with bovine trichomoniasis in beef cattle identified by a questionnaire. ( 24623635 )
2014
35
Prevalence of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among pregnant women receiving antenatal care in Southwestern Nigeria. ( 25544891 )
2014
36
Prevalence of Trichomoniasis, Vaginal Candidiasis, Genital Herpes, Chlamydiasis, and Actinomycosis among Urban and Rural Women of Haryana, India. ( 26316979 )
2014
37
An emerging Mycoplasma associated with trichomoniasis, vaginal infection and disease. ( 25337710 )
2014
38
Diagnosis of Tritrichomonas foetus-infected bulls, an ultimate approach to eradicate bovine trichomoniasis in US cattle? ( 23082032 )
2013
39
Insights into trichomoniasis as a result of highly sensitive molecular diagnostics screening in a high-prevalence sexually transmitted infection community. ( 23944153 )
2013
40
Trichomoniasis: How do we diagnose in a resource poor setting? ( 23919051 )
2013
41
Trichomoniasis: the "neglected" sexually transmitted disease. ( 24275268 )
2013
42
Trichomoniasis and HIV interactions: a review. ( 23605851 )
2013
43
Molecular dynamic simulation and inhibitor prediction of cysteine synthase structured model as a potential drug target for trichomoniasis. ( 24073401 )
2013
44
Culture and immunochromatographic technique for diagnosis of trichomoniasis. ( 24385065 )
2013
45
TvMP50 is an immunogenic metalloproteinase during male trichomoniasis. ( 23579185 )
2013
46
Use of culture and immunochromatographic technique for diagnosis of trichomoniasis in Sri Lanka. ( 24081173 )
2013
47
Trichomoniasis--an important cofactor of human immunodeficiency virus infection. ( 23745375 )
2013
48
Intravaginal metronidazole/miconazole for the treatment of vaginal trichomoniasis. ( 23949586 )
2013
49
Spatial and temporal epidemiology of bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina). ( 23518247 )
2013
50
Conventional vs. liquid-based cytology Pap smears for diagnosing trichomoniasis. ( 22534266 )
2012

Variations for Trichomoniasis

Expression for Trichomoniasis

Search GEO for disease gene expression data for Trichomoniasis.

Pathways for Trichomoniasis

Pathways related to Trichomoniasis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.63 CD79A IL2 IRF6
2
Show member pathways
11.01 CXCL8 IL2 IRF6
3
Show member pathways
10.96 CXCL8 IL2

GO Terms for Trichomoniasis

Sources for Trichomoniasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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