MCID: TRC010
MIFTS: 37

Trichotillomania malady

Neuronal diseases category

Summaries for Trichotillomania

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 63Wikipedia, 46OMIM, 32MalaCards
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NIH Rare Diseases:42 Trichotillomania is an impulse control disorder characterized by an overwhelming urge to repeatedly pull out one's own hair (usually on the scalp), resulting in hair loss (alopecia). the eyelashes, eyebrows, and beard can also be affected. many affected individuals feel extreme tension when they feel an impulse, followed by relief, gratification or pleasure afterwards. the condition may be mild and manageable, or severe and debilitating. some individuals chew or swallow the hair they pull out (trichophagy), which can result in gastrointestinal problems. the exact cause of the condition is unknown. treatment typically involves psychotherapy (including cognitive behavior therapy) and/or drug therapy, but these are not always effective. last updated: 11/30/2012

MalaCards: Trichotillomania, also known as hair-pulling syndrome, is related to stereotypic movement disorder and obsessive-compulsive disorder. An important gene associated with Trichotillomania is SLITRK1 (SLIT and NTRK-like family, member 1). Affiliated tissues include skin, brain and testes, and related mouse phenotypes are integument and behavior/neurological.

Disease Ontology:8 An impulse control disorder that involves the uncontrollable plucking of ones hair.

Wikipedia:63 Trichotillomania (pronounced /ˌtrɪkəˌtɪləˈmeɪniə/ TRIK-ə-TIL-ə-MAY-NEE-ə, also known as... more...

Description from OMIM:46 613229

Aliases & Classifications for Trichotillomania

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Sources:
8Disease Ontology, 9diseasecard, 42NIH Rare Diseases, 22GTR, 46OMIM, 10DISEASES, 60UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

trichotillomania 8 9 42 22 46 10 60
hair-pulling syndrome 42


External Ids:

Disease Ontology8 DOID:0050587
OMIM46 613229
ICD1025 F63.3

Related Diseases for Trichotillomania

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Trichotillomania:



Diseases related to trichotillomania

Clinical Features for Trichotillomania

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46OMIM
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Clinical features from OMIM:

613229

Clinical synopsis from OMIM:

613229

Drugs & Therapeutics for Trichotillomania

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Trichotillomania

Drug clinical trials:

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Search NIH Clinical Center for Trichotillomania

Search CenterWatch for Trichotillomania

Genetic Tests for Trichotillomania

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22GTR
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Genetic tests related to Trichotillomania:

id Genetic test Affiliating Genes
1 Trichotillomania22

Anatomical Context for Trichotillomania

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32MalaCards
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MalaCards organs/tissues related to Trichotillomania:

32
Skin, Brain, Testes

Animal Models for Trichotillomania or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Trichotillomania:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.6DLGAP3, HOXB8, PRL
2MP:00053868.1SLITRK1, DLGAP3, HOXB8, PRL
3MP:00036317.9PRL, HOXB8, DLGAP3, SLITRK1

Publications for Trichotillomania

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50PubMed
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Articles related to Trichotillomania:

(show top 50)    (show all 445)
idTitleAuthorsYear
1
Trichotillomania. (24049966)
2013
2
Trichotillomania with trichorhizophagia in a schizophrenic patient: Case report and review of literature. (22988332)
2012
3
Masquerading of trichotillomania in a family with monilethrix. (21224181)
2011
4
The efficacy of low-dose aripiprazole treatment for trichotillomania. (22104636)
2011
5
Cognitive-behavioral therapy for childhood repetitive behavior disorders: tic disorders and trichotillomania. (21440858)
2011
6
Movement decoupling: A self-help intervention for the treatment of trichotillomania. (20674888)
2011
7
Trichotillomania following herpetic neuralgia. (20798694)
2010
8
Trichotillomania in youth: a retrospective case series. (19496078)
2009
9
Trichotillomania. (18318881)
2008
10
Trichotillomania in children. (18515931)
2008
11
Clinical characteristics of trichotillomania with trichophagia. (18970906)
2008
12
Trichotillomania. (18380298)
2008
13
Laser hair removal as an option for treatment of trichotillomania: a case report. (17958868)
2007
14
Understanding and treating trichotillomania: what we know and what we don't know. (16650719)
2006
15
Trichotillomania in childhood: case series and review. (15121993)
2004
16
Giant trichophytobezoar in a pediatric patient with trichotillomania. (12612826)
2003
17
Trichotillomania. (12778604)
2003
18
Functional brain imaging and pharmacotherapy in trichotillomania. Single photon emission computed tomography before and after treatment with the selective serotonin reuptake inhibitor citalopram. (12369261)
2002
19
A case of resistant trichotillomania treated with risperidone-augmented fluvoxamine. (11320684)
2001
20
Recurrent trichobezoar in a case of trichotillomania. (21407883)
2001
21
Trichotillomania: a challenge to research and practice. (10779896)
2000
22
D8/17 in obsessive-compulsive disorder and trichotillomania. (10470312)
1999
23
Under-diagnosed psychiatric syndrome. I: Trichotillomania. (10497682)
1999
24
Trichobezoars in trichotillomania: case report and literature overview. (9773774)
1998
25
Trichotillomania and anorexia nervosa. (9168378)
1997
26
Trichotillomania: ophthalmic presentation. (7619458)
1995
27
Trichotillomania and obsessive-compulsive disorder. (7713862)
1995
28
Delusional parasitosis with trichotillomania. (7890955)
1994
29
Dermacase. Trichotillomania. (8199519)
1994
30
Pain thresholds are not elevated in trichotillomania. (7993963)
1994
31
Neurological soft signs in female trichotillomania patients, obsessive-compulsive disorder patients, and healthy control subjects. (8044043)
1994
32
Trichotillomania. (8070281)
1994
33
Culture-bound trichotillomania. (8465892)
1993
34
Trichotillomania. (8447795)
1993
35
Behavior therapy for obsessive-compulsive disorder and trichotillomania. Implications for Tourette syndrome. (1414641)
1992
36
Rates of Obsessive Compulsive Disorder in first degree relatives of patients with trichotillomania: a research note. (1634595)
1992
37
Familial trichotillomania. (2018177)
1991
38
Trichotillomania associated with the "Friar Tuck sign" and nail-biting. (2001629)
1991
39
Fluoxetine treatment of trichotillomania. (1993643)
1991
40
Trichotillomania (hair pulling) (2300111)
1990
41
Trichotillomania. (3235179)
1988
42
MAO inhibitor therapy in trichotillomania associated with depression: case report. (6725219)
1984
43
The adjunctive use of hypnosis in the treatment of trichotillomania: a case report. (7246470)
1981
44
Trichotillomania in adults. (7389405)
1980
45
Trichotillomania and trichobezoar in an infant. Psychological factors underlying this symptom. (690362)
1978
46
Trichotillomania. A clinicopathologic study of 24 cases. (5017262)
1972
47
Some observations on trichotillomania in children. (5782317)
1969
48
Eyelash and eyebrow pulling. (Trichotillomania) treatment of two adolescent girls. (5218374)
1965
49
Trichotillomania. (19992156)
1939
50
Case of Trichotillomania with Delusions of Nasal Origin. (19980084)
1918

Genetic Variations for Trichotillomania

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Expression for genes affiliated with Trichotillomania

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trichotillomania

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Pathways for genes affiliated with Trichotillomania

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Compounds for genes affiliated with Trichotillomania

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GO Terms for genes affiliated with Trichotillomania

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Products for genes affiliated with Trichotillomania

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Trichotillomania

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet