MCID: TRC012
MIFTS: 43

Trichuriasis malady

Infectious diseases category

Summaries for Trichuriasis

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A parasitic helminthiasis infectious disease that involves parasitic infection located in intestine in humans, has material basis in trichuris trichiura, which is transmitted by ingestion of food contaminated with egg-carrying soil. the infection has symptom abdominal pain, has symptom diarrhea, has symptom rectal prolapse and has symptom growth retardation.

MalaCards: Trichuriasis, also known as infection by trichuris trichiura, is related to ascariasis and strongyloidiasis, and has symptoms including abdominal pain, diarrhea and rectal prolapse. An important gene associated with Trichuriasis is LILRA3 (leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3). The drugs albendazole and ivermectin have been mentioned in the context of this disorder. Affiliated tissues include intestine in humans, colon and t cells.

CDC:3 An estimated 604-795 million people in the world are infected with whipworm. Whipworm, hookworm, and Ascaris are known as soil-transmitted helminths (parasitic worms). Together, they account for a major burden of disease worldwide.

Wikipedia:63 Trichuriasis also known as whipworm infection is an infection by the parasitic worm Trichuris trichiura... more...

Aliases & Classifications for Trichuriasis

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

trichuriasis 8 42 10
infection by trichuris trichiura 60
infection by trichuris trichura 8
trichuris trichiura infection 8
trichuriasis infection 8
whipworm infection 42
trichocephaliasis 42
whipworm disease 8


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Disease Ontology8 DOID:1252
ICD9CM27 127.3
MeSH34 D014257
ICD1025 B79

Related Diseases for Trichuriasis

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17GeneCards, 18GeneDecks
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Diseases related to Trichuriasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1ascariasis10.6
2strongyloidiasis10.1
3ancylostomiasis10.1
4enterobiasis10.1
5hepatitis10.0HBE1
6hepatitis b10.0HBE1
7rheumatoid arthritis10.0HLA-DRB4, LILRA3, NAMPT
8deficiency anemia9.9
9necatoriasis9.9
10hymenolepiasis9.9
11tungiasis9.9
12rectal prolapse9.9
13iron deficiency anemia9.9
14yellow fever9.9
15typhoid fever9.9
16scurvy9.9
17gastroenteritis9.9
18hemolytic anemia9.9
19malaria9.9

Graphical network of diseases related to Trichuriasis:



Diseases related to trichuriasis

Clinical Features for Trichuriasis

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8Disease Ontology
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Symptoms:

8
  • abdominal pain
  • diarrhea
  • rectal prolapse
  • growth retardation

Drugs & Therapeutics for Trichuriasis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Trichuriasis

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Anatomical Context for Trichuriasis

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Trichuriasis:

32
Colon, T cells

FMA organs/tissues related to Trichuriasis:

14
Intestine in humans

Animal Models for Trichuriasis or affiliated genes

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Publications for Trichuriasis

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50PubMed
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Articles related to Trichuriasis:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Growth reduction among primary schoolchildren with light trichuriasis in Malaysia treated with albendazole. (23682433)
2013
2
Trichuriasis diagnosed by colonoscopy: case report and review of the literature spanning 22 years in mainland China. (23523058)
2013
3
Household social determinants of ascariasis and trichuriasis in North Central Venezuela. (24029148)
2012
4
Trichuriasis colitis detected by Doppler sonography. (20571789)
2010
5
Sonographic whipworm dance in trichuriasis. (19321687)
2009
6
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. (16679166)
2006
7
Computed tomographic findings of trichuriasis. (16830393)
2006
8
Age- and infection intensity-dependent cytokine and antibody production in human trichuriasis: the importance of IgE. (11865424)
2002
9
Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru. (12055813)
2002
10
A comparison of cellular and humoral immune responses to trichuroid derived antigens in human trichuriasis. (11874563)
2002
11
Use of Fenbendazole in Treating Trichuriasis in Colobus Monkeys. (23985619)
1999
12
Ascariasis, trichuriasis, and growth of schoolchildren in Northeastern Peninsular Malaysia. (10772554)
1998
13
Immunoepidemiology of intestinal helminth infections. 4. Immunopathology in trichuriasis: lessons from the mouse model. (7974660)
1994
14
Does ascariasis, trichuriasis and hookworm infection predispose to non-specific abdominal symptoms among adults in endemic areas? (8009635)
1994
15
School performance, nutritional status and trichuriasis in Jamaican schoolchildren. (7531045)
1994
16
Serum isotype responses after treatment of human trichuriasis. (7974688)
1994
17
Transmission of trichuriasis in a sexual setting? (7849126)
1994
18
A comparative study on the efficacy of albendazole and mebendazole in the treatment of ascariasis, hookworm infection and trichuriasis. (7939948)
1993
19
Do ascariasis, trichuriasis and hookworm infections predispose to non-specific abdominal symptoms among adults in endemic areas? (8273160)
1993
20
Ascariasis and trichuriasis in Cameroon. (2068772)
1991
21
The evidence for predisposition to trichuriasis in humans: comparison of institutional and community studies. (3250338)
1988
22
Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis. (4039128)
1985
23
Evaluation of mebendazole in trichuriasis. (7228360)
1980
24
Trichuriasis. Roentgenographic features and differential diagnosis with lymphoid hyperplasia. (450490)
1979
25
Evaluation of a new antihelminthic for trichuriasis, hookworm, and stronglyloidiasis. (381876)
1979
26
Clinical evaluation of mebendazole in trichuriasis in children. (457245)
1979
27
A review of trichuriasis, its incidence, pathogenicity and treatment. (350571)
1978
28
Pathophysiology of swine trichuriasis. (883715)
1977
29
Treatment for trichuriasis with oxantel. (1008134)
1976
30
Trichuriasis in Calcasieu Parish, Southwest Louisiana. (1185028)
1975
31
Treatment of trichuriasis with a new drug, mebendazole. (1113237)
1975
32
Experiencw with bitoscanate in hookworm disease and trichuriasis in Mexico. (769064)
1975
33
Clinical effectiveness of mebendazole in the treatment of trichuriasis. (813944)
1975
34
Mebendazole. Treatment of trichuriasis and ascariasis in Bahamian children. (4479643)
1974
35
Diphetarsone in trichuriasis. (4814638)
1974
36
A clinical evaluation of mebendazole in the treatment of trichuriasis. (4596042)
1974
37
Trial of thiabendazole and viprynium embonate in combination for trichuriasis in aboriginal children. (4773610)
1973
38
Treatment of trichuriasis. (5046384)
1972
39
Dichlorvos: an anthelmintic for primate trichuriasis. (4249649)
1970
40
Efficacy of methyridine 2- [2-methoxyethyl] pyridine in the treatment of trichuriasis in camel (Camelus dromedarius). (5690253)
1968
41
Aleixo de Abreu [1568-1630], author of the earliest book on tropical medicine describing amoebiasis, malaria, typhoid fever, scurvy, yellow fever, dracontiasis, trichuriasis and tungiasis in 1623. (4869639)
1968
42
Trichuriasis. (5863191)
1965
43
THE THERAPY OF TRICHURIASIS WITH A COMBINATION OF THIABENDAZOLE AND PYRVINIUM PAMOATE. (14317649)
1965
44
A TETRACHLORETHYLENE-CHENOPODIUM PREPARATION IN TRICHURIASIS. (14073709)
1963
45
Experimental trichuriasis. II. Anthelmintic screening against Trichuris muris in the albino mouse. (13752160)
1961
46
Effect of dithiazanine in ascariasis, trichuriasis, enterobiasis and ankylostomiasis. (13924257)
1961
47
Therapy of trichuriasis and ancylostomiasis with dithiazanine. (13698988)
1960
48
Treatment of trichuriasis with dithiazanine in a hospital for mental defectives. (14429828)
1960
49
Treatment of trichuriasis with dithiazanine; a preliminary report. (13608089)
1959
50
Therapy of trichuriasis and ascariasis with dithiazanine. (13533741)
1958

Genetic Variations for Trichuriasis

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Expression for genes affiliated with Trichuriasis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trichuriasis

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Pathways for genes affiliated with Trichuriasis

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Compounds for genes affiliated with Trichuriasis

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GO Terms for genes affiliated with Trichuriasis

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16Gene Ontology
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Biological processes related to Trichuriasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of release of cytochrome c from mitochondriaGO:09020010.1HRK, MFF
2chemotaxisGO:0069359.7RNASE2, PROK2, CCL23

Products for genes affiliated with Trichuriasis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Trichuriasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet