MCID: TRC012
MIFTS: 43

Trichuriasis malady

Infectious diseases category

Summaries for Trichuriasis

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A parasitic helminthiasis infectious disease that involves parasitic infection located in intestine in humans, has material basis in trichuris trichiura, which is transmitted by ingestion of food contaminated with egg-carrying soil. the infection has symptom abdominal pain, has symptom diarrhea, has symptom rectal prolapse and has symptom growth retardation.

MalaCards: Trichuriasis, also known as infection by trichuris trichiura, is related to ascariasis and strongyloidiasis, and has symptoms including abdominal pain, diarrhea and rectal prolapse. An important gene associated with Trichuriasis is LILRA3 (leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3). The drugs albendazole and ivermectin have been mentioned in the context of this disorder. Affiliated tissues include intestine in humans, colon and t cells.

CDC:3 An estimated 604-795 million people in the world are infected with whipworm. Whipworm, hookworm, and Ascaris are known as soil-transmitted helminths (parasitic worms). Together, they account for a major burden of disease worldwide.

Wikipedia:63 Trichuriasis also known as whipworm infection is an infection by the parasitic worm Trichuris trichiura... more...

Aliases & Classifications for Trichuriasis

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

trichuriasis 8 42 10
infection by trichuris trichiura 60
infection by trichuris trichura 8
trichuris trichiura infection 8
trichuriasis infection 8
whipworm infection 42
trichocephaliasis 42
whipworm disease 8


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Disease Ontology8 DOID:1252
ICD9CM27 127.3
MeSH34 D014257
ICD1025 B79

Related Diseases for Trichuriasis

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17GeneCards, 18GeneDecks
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Diseases related to Trichuriasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1ascariasis10.6
2strongyloidiasis10.1
3ancylostomiasis10.1
4enterobiasis10.1
5hepatitis10.0HBE1
6hepatitis b10.0HBE1
7rheumatoid arthritis10.0HLA-DRB4, LILRA3, NAMPT
8deficiency anemia9.9
9necatoriasis9.9
10hymenolepiasis9.9
11tungiasis9.9
12rectal prolapse9.9
13iron deficiency anemia9.9
14yellow fever9.9
15typhoid fever9.9
16scurvy9.9
17gastroenteritis9.9
18hemolytic anemia9.9
19malaria9.9

Graphical network of diseases related to Trichuriasis:



Diseases related to trichuriasis

Clinical Features for Trichuriasis

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8Disease Ontology
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Symptoms:

8
  • abdominal pain
  • diarrhea
  • rectal prolapse
  • growth retardation

Drugs & Therapeutics for Trichuriasis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Trichuriasis

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Anatomical Context for Trichuriasis

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Trichuriasis:

32
Colon, T cells

FMA organs/tissues related to Trichuriasis:

14
Intestine in humans

Animal Models for Trichuriasis or affiliated genes

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Publications for Trichuriasis

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50PubMed
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Articles related to Trichuriasis:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Growth reduction among primary schoolchildren with light trichuriasis in Malaysia treated with albendazole. (23682433)
2013
2
Trichuriasis diagnosed by colonoscopy: case report and review of the literature spanning 22 years in mainland China. (23523058)
2013
3
Household social determinants of ascariasis and trichuriasis in North Central Venezuela. (24029148)
2012
4
Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study. (21666788)
2011
5
Trichuriasis and low-iron status in schoolchildren from Northwest Mexico. (20700138)
2010
6
Colonic transcriptional profiling in resistance and susceptibility to trichuriasis: phenotyping a chronic colitis and lessons for iatrogenic helminthosis. (20687192)
2010
7
Sonographic whipworm dance in trichuriasis. (19321687)
2009
8
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. (16679166)
2006
9
Computed tomographic findings of trichuriasis. (16830393)
2006
10
Comparative efficacy of albendazole and three brands of mebendazole in the treatment of ascariasis and trichuriasis. (15293971)
2004
11
Immunity, immunoregulation and the ecology of trichuriasis and ascariasis. (15771679)
2004
12
A case of gastroenteritis associated with gastric trichuriasis. (12808334)
2003
13
Age- and infection intensity-dependent cytokine and antibody production in human trichuriasis: the importance of IgE. (11865424)
2002
14
Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru. (12055813)
2002
15
Efficacy of multiple dose mebendazole against trichuriasis in Thai and Karen patients. (11289001)
2000
16
Use of Fenbendazole in Treating Trichuriasis in Colobus Monkeys. (23985619)
1999
17
Ascariasis, trichuriasis, and growth of schoolchildren in Northeastern Peninsular Malaysia. (10772554)
1998
18
Basal and ACTH-stimulated plasma aldosterone concentrations are normal or increased in dogs with trichuriasis-associated pseudohypoadrenocorticism. (7983625)
1994
19
School performance, nutritional status and trichuriasis in Jamaican schoolchildren. (7531045)
1994
20
Transmission of trichuriasis in a sexual setting? (7849126)
1994
21
A comparative study on the efficacy of albendazole and mebendazole in the treatment of ascariasis, hookworm infection and trichuriasis. (7939948)
1993
22
Modulation of cytokine production and response phenotypes in murine trichuriasis. (1437236)
1992
23
Helper T-cell subsets in mouse trichuriasis. (15463401)
1991
24
Trichuris and trichuriasis in humans. (2683614)
1989
25
The evidence for predisposition to trichuriasis in humans: comparison of institutional and community studies. (3250338)
1988
26
Gastric trichuriasis in a black and white colobus monkey. (3505990)
1986
27
Selective primary health care: strategies for control of disease in the developing world. XII. Ascariasis and trichuriasis. (6377443)
1984
28
Benzimidazoles in the treatment of trichuriasis: a review. (6378109)
1984
29
Efficacy Of Mebendazole In Treatment And Control Of Trichuriasis In Korea. (12902674)
1983
30
Is trichuriasis associated with iron deficiency anemia? (464198)
1979
31
Evaluation of mebendazole for the treatment of trichuriasis. (470773)
1979
32
Evaluation of a new antihelminthic for trichuriasis, hookworm, and stronglyloidiasis. (381876)
1979
33
Further experience with mebendazole in the treatment of symptomatic trichuriasis in children. (646017)
1978
34
A review of trichuriasis, its incidence, pathogenicity and treatment. (350571)
1978
35
Pathophysiology of swine trichuriasis. (883715)
1977
36
Treatment for trichuriasis with oxantel. (1008134)
1976
37
Algorithms in the diagnosis and management of exotic diseases. IX. Trichuriasis. (1245771)
1976
38
Trichuriasis in Calcasieu Parish, Southwest Louisiana. (1185028)
1975
39
Treatment of trichuriasis with a new drug, mebendazole. (1113237)
1975
40
A clinical evaluation of the efficacy of mebendazole in the treatment of trichuriasis. (1098155)
1975
41
Clinical effectiveness of mebendazole in the treatment of trichuriasis. (813944)
1975
42
Mebendazole. Treatment of trichuriasis and ascariasis in Bahamian children. (4479643)
1974
43
A clinical evaluation of mebendazole in the treatment of trichuriasis. (4596042)
1974
44
Study of oxyuriasis, trichuriasis in children and evaluation of mebendazole. (4426672)
1974
45
Prevalence of human ascariasis and trichuriasis in San Juan and vicinity, Puerto Rico. (4711667)
1973
46
Clinical trichuriasis produced experimentally in growing pigs. I. Pathology of infection. (4519450)
1973
47
Treatment of trichuriasis. (5046384)
1972
48
Aleixo de Abreu [1568-1630], author of the earliest book on tropical medicine describing amoebiasis, malaria, typhoid fever, scurvy, yellow fever, dracontiasis, trichuriasis and tungiasis in 1623. (4869639)
1968
49
Treatment of trichuriasis with dithiazanine; a preliminary report. (13608089)
1959
50
The severity of trichuriasis among children in Costa Rica. (13406571)
1957

Genetic Variations for Trichuriasis

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Expression for genes affiliated with Trichuriasis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trichuriasis

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Pathways for genes affiliated with Trichuriasis

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Compounds for genes affiliated with Trichuriasis

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GO Terms for genes affiliated with Trichuriasis

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16Gene Ontology
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Biological processes related to Trichuriasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of release of cytochrome c from mitochondriaGO:09020010.1HRK, MFF
2chemotaxisGO:0069359.7RNASE2, PROK2, CCL23

Products for genes affiliated with Trichuriasis

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  • Antibodies
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Sources for Trichuriasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet