Sources: 1BitterDB, 4ClinicalTrials, 7Cochrane Library, 10DGIdb, 14DrugBank, 29HMDB, 33IUPHAR, 46NDF-RT, 50Novoseek, 56PharmGKB, 68UMLSSee all MalaCards sources |
Drugs for Trichuriasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB): (show all 25)
| id | | Name | Status | Phase | Clinical Trials | Cas Number | PubChem Id |
|---|
| 1 | | Piperazine | approved, vet_approved | Phase 4, Phase 3 | 24 | 110-85-0 | 4837 | 1,4-Diazacyclohexane 1,4-Diethylenediamine 1,4-Piperazine 110-85-0 14007-05-7 (unspecified hydrobromide) 142-63-2 (hexahydrate) 142-64-3 (di-hydrochloride) 14538-56-8 (phosphate[1:1]) 16832-43-2 (unspecified hydrate) 1951-97-9 (unspecified phosphate) 3597-26-0 (unspecified sulfate) 5-23-01-00030 (Beilstein Handbook Reference) 6094-40-2 (unspecified hydrochloride) 7542-23-6 (mono-hydrochloride) 8017-90-1 8027-81-4 8057-14-5 (unspecified salt) 80621_FLUKA 854880-15-2 861800-35-3 AB1003720 AC1L1J2E AC1Q1IA7 AC1Q1IA8 AC1Q1IA9 AKOS000269028 AR-1L1009 ARONIS23910 Anthalazine Antiren Asca-Trol No. 3 BIDD:GT0273 BRN 0102555 C07973 CCRIS 5950 CHEBI:28568 CHEMBL1412 CID4837 D00807 DB00592 Diethylenediamine Diethyleneimine Dispermine DivK1c_000038 EINECS 203-808-3 Eraverm Eraverm (VAN) Fluphenazine dihydrochloride HMS1920H20 HMS2092A03 HMS500B20 HSDB 1093 Hexahydro-1,4-diazine Hexahydropyrazine I14-11172 IDI1_000038 InChI=1/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H Jsp000824 KBio1_000038 KBio2_001593 KBio2_004161 KBio2_006729 KBioSS_001593 LS-517 LTBB000432 Lumbrical MolPort-000-872-010 NCGC00094762-01 NCGC00094762-02 NCIOpen2_000984 NCIOpen2_000988 NCIOpen2_001024 NCIOpen2_001031 NCIOpen2_001033 NCIOpen2_001071 | NCIOpen2_001073 NCIOpen2_001111 NCIOpen2_001151 NCIOpen2_001231 NCIOpen2_001262 NCIOpen2_001269 NCIOpen2_004830 NCIOpen2_004834 NCIOpen2_004862 NCIOpen2_004874 NCIOpen2_004904 NCIOpen2_004910 NCIOpen2_004914 NCIOpen2_004942 NCIOpen2_004952 NCIOpen2_004954 NCIOpen2_004982 NCIOpen2_004992 NCIOpen2_004994 NCIOpen2_005022 NCIOpen2_005032 NCIOpen2_005034 NCIOpen2_005062 NCIOpen2_005072 NCIOpen2_005102 NCIOpen2_005108 NCIOpen2_005145 NCIOpen2_005182 NCIOpen2_005185 NCIOpen2_005187 NCIOpen2_005200 NCIOpen2_005575 NCIOpen2_005980 NCIOpen2_009422 NINDS_000038 NSC 474 NSC474 P0446 P0447 P45907_SIAL PIPERAZINE (HEXAHYDRATE) PZE Piperazidine Piperazin Piperazin [German] Piperazin [Germany] Piperazine (USP) Piperazine Dihydrochloride Dihydrochloride Hydrate Piperazine Hexa-Hydrate Piperazine [UN2579] [Corrosive] Piperazine [UN2579] [Corrosive] Piperazine [USAN] Piperazine anhydrous Piperazine hexahydrate Piperazine hydrate Piperazine, anhydrous Pipersol Pyrazine hexahydride Pyrazine, hexahy SPECTRUM1500490 Spectrum5_001817 Spectrum_001113 UN2579 UNII-1RTM4PAL0V Upixon Uvilon Vermex Vermizine Vermizine (TN) WLN: T6M DMTJ Worm-A-Ton Worm-away Wurmirazin nchembio814-comp12 piperazine piperazinium oleate | |
| | 2 | | Mebendazole | approved, vet_approved | Phase 4, Phase 3 | 24 | 31431-39-7 | 4030 | (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester (5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester (5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI) 31431-39-7 46404_FLUKA 46404_RIEDEL 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester 5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester AB00052203 AC-12064 AC1L1H98 AC1Q44DR AKOS000539066 Abello Farmacia Brand of Mebendazole Anti Worm Anti-Worm Ardeypharm Brand of Mebendazole BAS 00341140 BIDD:GT0087 BPBio1_000257 BRD-K77987382-001-01-7 BRD-K77987382-001-06-6 BSPBio_000233 BSPBio_003178 Bantenol Banworm Besantin Bio-0458 Bio-0803 Boots Brand of Mebendazole Boots Threadworm Treatment CAS-31431-39-7 CBDivE_010559 CCRIS 4479 CHEBI:6704 CHEMBL685 CID4030 CPD000036734 Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI) Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester D00368 D008463 DB00643 Degort's Brand of Mebendazole Diba Brand of Mebendazole DivK1c_000751 EINECS 250-635-4 Elfar Brand of Mebendazole Equivurm Plus Esteve Brand of Mebendazole HMS1536H11 HMS1568L15 HMS1921F03 HMS2090B03 HMS2092B15 HMS502F13 HSDB 3232 Healthypharm Brand of Mebendazole I06-2075 IDI1_000751 Janssen Brand of Mebendazole KBio1_000751 KBio2_001778 KBio2_004346 KBio2_006914 KBio3_002398 KBioGR_000712 KBioSS_001778 LS-48951 Leidapharm Brand of Mebendazole Lomper M2523_FLUKA M2523_SIGMA MBDZ MEBENDAZOLE, 99% MLS000028491 Madicure Mebendan Mebendazol Mebendazol [INN-Spanish] Mebendazole (JAN/USP) | Mebendazole (JAN/USP/INN) Mebendazole [USAN:INN:BAN:JAN] Mebendazole(USAN) Mebendazolum Mebendazolum [INN-Latin] Mebenoazole Mebenvet Mebex Mebutar Methyl 5-benzoyl benzimidazole-2-carbamate Methyl 5-benzoyl-2-benzimidazolecarbamate Methyl 5-benzoyl-2-benzimidazolylcarbamate Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate MolPort-000-765-625 MolPort-001-889-615 Mébendazole N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French] N-2 (5-Benzoyl-benzimidazole) carbamate de methyle N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French] NCGC00016806-01 NCGC00016806-02 NCGC00021698-03 NCGC00021698-04 NCGC00021698-05 NCGC00021698-06 NINDS_000751 NSC 184849 NSC184849 Norgine Brand of Mebendazole Noverme Oprea1_278237 Oprea1_768530 Ovitelmin Pantelmin Pfizer Brand of Mebendazole Prestwick0_000217 Prestwick1_000217 Prestwick2_000217 Prestwick3_000217 Prestwick_310 Pripsen Mebendazole Probes1_000013 Probes2_000149 R 17,635 R 17635 R-17635 R17635 SAM002548959 SMR000036734 SPBio_001442 SPBio_002154 SPECTRUM1501110 SSL Brand of Mebendazole STK093862 Spectrum2_001401 Spectrum3_001439 Spectrum4_000416 Spectrum5_001381 Spectrum_001298 Sqworm Streger Brand of Mebendazole Sufil Surfont TL8002405 Taxandria Brand of Mebendazole Tedec Meiji Brand of Mebendazole Telmin TimTec1_000869 UNII-81G6I5V05I Vermicidin Vermicol Vermidil Vermin Vermirax Vermox Vermox (TN) Verpanyl Versid Wormkuur ZINC00121541 mebendazole methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate |
| | 3 | | Albendazole | approved, vet_approved | Phase 4 | 80 | 54965-21-8 | 2082 | ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French] (5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester (5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester 5-(Propylthio)-2-carbomethoxyaminobenzimidazole 54965-21-8 A4673_FLUKA A4673_SIGMA AB00052377 AC-015 AC1L1CVL AC1Q2YKD AKOS000540882 Albendazol Albendazol [INN-Spanish] Albendazole Albendazole (JAN/USP/INN) Albendazole Armstrong Brand Albendazole Diba Brand Albendazole Fustery Brand Albendazole Hormona Brand Albendazole Liferpal Brand Albendazole Monohydrochloride Albendazole Noe-Socopharm Brand Albendazole Pfizer Brand Albendazole Sanicoopa Brand Albendazole Valdecasas Brand Albendazole [USAN:INN:BAN:JAN] Albendazolum Albendazolum [INN-Latin] Albendoral Albenza Albenza (TN) Albenza, Eskazole, Zentel, Andazol, Albendazole Armstrong Brand of Albendazole BAS 00439961 BB_SC-1386 BIDD:GT0615 BIM-0051849.0001 BPBio1_000038 BRD-K79131256-001-04-7 BSPBio_000034 BSPBio_002548 Bendapar Bilutac C01779 CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER CAS-54965-21-8 CHEBI:16664 CHEBI:506787 CHEMBL1483 CID2082 CPD000036735 Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester ChemDiv1_000190 ChemDivAM_000003 D00134 D015766 DB00518 Diba Brand of Albendazole Digezanol Disthelm Disthelm, Mediamix V DivK1c_000704 EINECS 259-414-7 Endoplus Eskazole Fustery Brand of Albendazole Gascop HMS1568B16 HMS1922K04 HMS2090G19 HMS2093K13 HMS502D06 HMS587I14 HSDB 7444 Hormona Brand of Albendazole I01-0380 IDI1_000704 InChI=1/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) KBio1_000704 | KBio2_002012 KBio2_004580 KBio2_007148 KBioGR_000801 KBioSS_002012 LS-50618 Liferpal Brand of Albendazole Lurdex MLS000069722 Mediamix V Disthelm Methyl 5-(propyl-thio)-2-benzimidazolecarbamate Methyl 5-(propylthio)-2-benzimidazolecarbamate Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate Methyl-5-[propylthio]-2-benzimidazole carbamate Metiazol MolPort-000-726-929 MolPort-000-760-571 MolPort-001-932-918 Monohydrochloride, Albendazole NCGC00016876-01 NCGC00016876-02 NCGC00022896-03 NCGC00022896-04 NCGC00022896-05 NCGC00022896-06 NCGC00022896-07 NINDS_000704 NSC 220008 NSC220008 Noe Socopharm Brand of Albendazole Noe-Socopharm Brand of Albendazole O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate Oprea1_429292 Oprea1_585016 Oprea1_640007 Pfizer Brand of Albendazole Prestwick0_000247 Prestwick1_000247 Prestwick2_000247 Prestwick3_000247 Prestwick_675 Proftril Ricobendazole Rycobendazole S1640_Selleck SAM002589939 SK&F 62979 SK&F-62979 SK&F62979 SKF 62979 SKF-62979 SKF62979 SMR000036735 SPBio_002253 SPECTRUM1503903 STK387550 STL046130 STOCK2S-67946 Sanicoopa Brand of Albendazole Smith Kline & French Brand of Albendazole SmithKline Beecham Brand of Albendazole Spectrum4_000201 Spectrum5_001567 Spectrum_001532 TL8003543 UNII-F4216019LN V Disthelm, Mediamix VU0239747-6 Valbazen Valdecasas Brand of Albendazole ZINC17146904 Zental Zentel [5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester [5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester albendazole methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate | |
| | 4 | | Neuromuscular Blocking Agents | | Phase 4 | 414 | | | | 5 | | Anthelmintics | | Phase 4, Phase 3 | 431 | | | | 6 | | Neuromuscular Depolarizing Agents | | Phase 4 | 135 | | | | 7 | | Peripheral Nervous System Agents | | Phase 4 | 22776 | | | | 8 | | Piperazine citrate | | Phase 4, Phase 3 | 24 | | | | 9 | | Adjuvants, Immunologic | | Phase 4 | 2484 | | | | 10 | | Oxantel | | Phase 4 | 1 | | | | 11 | | Neuromuscular Agents | | Phase 4 | 1129 | | | | 12 | | Antiprotozoal Agents | | Phase 4 | 1986 | | | | 13 | | Antimitotic Agents | | Phase 4, Phase 3 | 5498 | | | | 14 | | Anti-Infective Agents | | Phase 4, Phase 3 | 21402 | | | | 15 | | Antirheumatic Agents | | Phase 4 | 10627 | | | | 16 | | Antiparasitic Agents | | Phase 4, Phase 3 | 2127 | | | | 17 | | Pyrantel | | Phase 4 | 13 | | | | 18 | | Pyrantel Pamoate | | Phase 4 | 13 | | | | 19 | | Citric Acid | nutraceutical, vet_approved | Phase 4, Phase 3 | 1106 | 77-92-9 | 311 | 2-Hydroxy-1,2,3-propanetricarboxylate 2-Hydroxy-1,2,3-propanetricarboxylic acid 2-Hydroxytricarballylic acid 3-Carboxy-3-hydroxypentane-1,5-dioate 3-Carboxy-3-hydroxypentane-1,5-dioic acid Aciletten Anhydrous citrate Anhydrous citric acid Chemfill Citraclean | Citrate Citretten Citric acid Citro Citronensäure E 330 Hydrocerol A Kyselina citronova Suby G Uro-trainer beta-Hydroxytricarballylate beta-Hydroxytricarballylic acid |
| | 20 | | Citrate | Nutraceutical | Phase 4, Phase 3 | 1106 | | | | 21 | | Vaccines | | Phase 2 | 6428 | | | | 22 | | Pharmaceutical Solutions | | Phase 2 | 7793 | | | | 23 | | Cayenne | Nutraceutical | Phase 2 | 17 | | | | 24 | | Praziquantel | approved, vet_approved | | 37 | 55268-74-1 | 4891 | (.+-)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one (11bS)-2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one 135526-78-2 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazinoe(2,1a)isoquinolin-4-one 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one 2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one 2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a) isoquinolin-4-one 46648_FLUKA 46648_RIEDEL 5-24-03-00361 (Beilstein Handbook Reference) 55268-74-1 57452-31-0 8440, EMBAY AB00052075 AC-11670 AC1L1J6N AKOS000541869 Azinox BAS 00347357 BPBio1_000088 BRD-A21858158-001-05-2 BRN 0761557 BSPBio_000080 BSPBio_002199 Bay-8440 Bayer Brand of Praziquantel Biliricide Biltricide Biltricide (TN) Biltricide, Droncit, Praziquantel Bio-0456 C07367 CCRIS 4114 CHEMBL976 CID4891 CPD000037139 Cesol Cisticid Cutter Cutter Tape Tabs Cysticide D00471 D011223 DB01058 DivK1c_000130 Droncit Drontsit EINECS 259-559-6 EINECS 260-741-2 EMBAY-8440 EU-0100909 Embay 8440 HMS1568D22 HMS1920J06 HMS2090J19 | HMS2092A09 HMS500G12 I06-0088 IDI1_000130 InChI=1/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H KBio1_000130 KBio2_001599 KBio2_004167 KBio2_006735 KBio3_001699 KBioGR_000963 KBioSS_001599 LS-23174 LS-7155 Lopac0_000909 MLS000028528 MLS000038419 MLS001201812 MLS001304085 Merck Brand of Praziquantel MolPort-001-926-470 NCGC00015818-05 NCGC00015818-11 NCGC00089733-02 NCGC00089733-03 NCGC00089733-04 NCGC00089733-05 NINDS_000130 NPFAPI-02 Oprea1_163497 P 4668 P4668_SIGMA Prasiquantel Praziquantel (JAN/USP/INN) Praziquantel [USAN:INN:BAN:JAN] Praziquantel, (+-)-Isomer Praziquantel, (R)-Isomer Praziquantel, (S)-Isomer Praziquantelum Praziquantelum [INN-Latin] Prestwick0_000260 Prestwick1_000260 Prestwick2_000260 Prestwick3_000260 Prestwick_402 Pyquiton S1691_Selleck SAM002264632 SMR000037139 SPBio_001295 SPBio_002299 SPECTRUM1500494 STK030186 Spectrum2_001288 Spectrum3_000550 Spectrum4_000482 Spectrum5_001064 Spectrum_001119 Traziquantel UNII-6490C9U457 praziquantel |
| | 25 | | Ivermectin | approved, vet_approved | | 57 | 70288-86-7 | 6474909, 46936176 | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside 22,23-Dihydroxy-avermectin B 22,23-Dihyroavermectin B1 5-O-Demethyl-22,23-dihydro-avermectin A1a 71827-03-7 AB00513813 AC1MJ4GR AC1N7O27 BPBio1_000322 BRD-K24652731-001-02-7 BSPBio_000292 CHEMBL341047 CID11957587 CID4330618 CID6321424 CID6419971 CID6427057 EU-0100693 FT-0082656 HMS1568O14 | HMS2089M09 I 8898 I8898_SIGMA IVERMECTIN Ivermectin Ivermectina Ivermectine Ivermectinum Lopac0_000693 MK-933 MLS001333247 MLS001333248 MLS002153248 MolPort-006-394-715 NCGC00094047-01 NCGC00094047-02 NCGC00094047-03 Prestwick2_000156 Prestwick3_000156 Prestwick_516 S1351_Selleck SMR000857211 |
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Interventional clinical trials: (show all 11)
| id | Name | Status | NCT ID | Phase |
|---|
| 1 | Efficacy Albendazole and Levamisole Against STH on Unguja | Completed | NCT00659997 | Phase 4 | | 2 | The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia | Completed | NCT01327469 | Phase 4 | | 3 | A Safety Study of Mebendazole in Children 2 to 10 Years of Age | Completed | NCT01173562 | Phase 3 | | 4 | Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity | Completed | NCT00671138 | Phase 2 | | 5 | Trichuris Suis Ova (TSO) Suspension Versus Placebo in Active Crohn's Disease | Completed | NCT01279577 | Phase 2 | | 6 | TSO in Pediatric Autistic Spectrum Disorders | Terminated | NCT01734941 | Phase 2 | | 7 | The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands | Completed | NCT01080989 | | | 8 | Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections | Completed | NCT00207753 | | | 9 | Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression | Completed | NCT00507221 | | | 10 | Immune Modulation From Trichuris Trichiura | Completed | NCT02399683 | | | 11 | Parasitic Infections of the Gastrointestinal Tract | Recruiting | NCT00001162 | |
Inferred drug relations via UMLS68/NDF-RT46:
Cochrane evidence based reviews: trichuriasis
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