MCID: TRC012
MIFTS: 43

Trichuriasis malady

Infectious diseases category

Summaries for Trichuriasis

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A parasitic helminthiasis infectious disease that involves parasitic infection located in intestine in humans, has material basis in trichuris trichiura, which is transmitted by ingestion of food contaminated with egg-carrying soil. the infection has symptom abdominal pain, has symptom diarrhea, has symptom rectal prolapse and has symptom growth retardation.

MalaCards: Trichuriasis, also known as infection by trichuris trichiura, is related to ascariasis and strongyloidiasis, and has symptoms including abdominal pain, diarrhea and rectal prolapse. An important gene associated with Trichuriasis is LILRA3 (leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3). The drugs albendazole and ivermectin have been mentioned in the context of this disorder. Affiliated tissues include intestine in humans, colon and t cells.

CDC:3 An estimated 604-795 million people in the world are infected with whipworm. Whipworm, hookworm, and Ascaris are known as soil-transmitted helminths (parasitic worms). Together, they account for a major burden of disease worldwide.

Wikipedia:63 Trichuriasis also known as whipworm infection is an infection by the parasitic worm Trichuris trichiura... more...

Aliases & Classifications for Trichuriasis

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

trichuriasis 8 42 10
infection by trichuris trichiura 60
infection by trichuris trichura 8
trichuris trichiura infection 8
trichuriasis infection 8
whipworm infection 42
trichocephaliasis 42
whipworm disease 8


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Disease Ontology8 DOID:1252
ICD9CM27 127.3
MeSH34 D014257
ICD1025 B79

Related Diseases for Trichuriasis

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17GeneCards, 18GeneDecks
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Diseases related to Trichuriasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1ascariasis10.6
2strongyloidiasis10.1
3ancylostomiasis10.1
4enterobiasis10.1
5hepatitis10.0HBE1
6hepatitis b10.0HBE1
7rheumatoid arthritis10.0HLA-DRB4, LILRA3, NAMPT
8deficiency anemia9.9
9necatoriasis9.9
10hymenolepiasis9.9
11tungiasis9.9
12rectal prolapse9.9
13iron deficiency anemia9.9
14yellow fever9.9
15typhoid fever9.9
16scurvy9.9
17gastroenteritis9.9
18hemolytic anemia9.9
19malaria9.9

Graphical network of diseases related to Trichuriasis:



Diseases related to trichuriasis

Clinical Features for Trichuriasis

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8Disease Ontology
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Symptoms:

8
  • abdominal pain
  • diarrhea
  • rectal prolapse
  • growth retardation

Drugs & Therapeutics for Trichuriasis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Trichuriasis

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Anatomical Context for Trichuriasis

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Trichuriasis:

32
Colon, T cells

FMA organs/tissues related to Trichuriasis:

14
Intestine in humans

Animal Models for Trichuriasis or affiliated genes

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Publications for Trichuriasis

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50PubMed
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Articles related to Trichuriasis:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Utilizing environmental, socioeconomic data and GIS techniques to estimate the risk for ascariasis and trichuriasis in Minas Gerais, Brazil. (22041638)
2012
2
Trichuriasis and low-iron status in schoolchildren from Northwest Mexico. (20700138)
2010
3
Trichuriasis colitis detected by Doppler sonography. (20571789)
2010
4
Comparative efficacy of albendazole and three brands of mebendazole in the treatment of ascariasis and trichuriasis. (15293971)
2004
5
Prolonged treatment with albendazole for massive trichuriasis infection. (15545874)
2004
6
Trichuriasis: localized inflammatory responses in the colon. (12236416)
2002
7
Efficacy of multiple dose mebendazole against trichuriasis in Thai and Karen patients. (11289001)
2000
8
Epidemiology of human geohelminth infections (ascariasis, trichuriasis and necatoriasis) in Lushui and Puer Counties, Yunnan Province, China. (11288999)
2000
9
Randomised trial of albendazole and pyrantel in symptomless trichuriasis in children. (9798586)
1998
10
Case in point. Trichuriasis. (7852465)
1995
11
Trichuriasis associated to severe transient Coomb's-negative hemolytic anemia and macroscopic hematuria. (11995911)
1995
12
Immunoepidemiology of intestinal helminth infections. 4. Immunopathology in trichuriasis: lessons from the mouse model. (7974660)
1994
13
Basal and ACTH-stimulated plasma aldosterone concentrations are normal or increased in dogs with trichuriasis-associated pseudohypoadrenocorticism. (7983625)
1994
14
Serum isotype responses after treatment of human trichuriasis. (7974688)
1994
15
Do ascariasis, trichuriasis and hookworm infections predispose to non-specific abdominal symptoms among adults in endemic areas? (8273160)
1993
16
Modulation of cytokine production and response phenotypes in murine trichuriasis. (1437236)
1992
17
Ascariasis and trichuriasis in Cameroon. (2068772)
1991
18
Helper T-cell subsets in mouse trichuriasis. (15463401)
1991
19
Host predisposition to trichuriasis: the mouse--T. muris model. (2762038)
1989
20
Epidemiological aspects of Trichuris and trichuriasis in Caribbean communities. (3299888)
1986
21
Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis. (4039128)
1985
22
Selective primary health care: strategies for control of disease in the developing world. XII. Ascariasis and trichuriasis. (6377443)
1984
23
Cortisone-induced immunotolerance to nematode infection in CBA/Ca mice. II. A model for human chronic trichuriasis. (6826206)
1983
24
Safety and efficacy of diphetarsone in the treatment of amoebiasis, non-pathogenic amoebiasis and trichuriasis. (6304952)
1983
25
Flubendazole and mebendazole in the treatment of trichuriasis and other helminthiases. (7332916)
1981
26
Trichuriasis. Roentgenographic features and differential diagnosis with lymphoid hyperplasia. (450490)
1979
27
Is trichuriasis associated with iron deficiency anemia? (464198)
1979
28
Evaluation of mebendazole for the treatment of trichuriasis. (470773)
1979
29
Further experience with mebendazole in the treatment of symptomatic trichuriasis in children. (646017)
1978
30
In vivo effects of mebendazole and levamisole in the treatment of trichuriasis and ascariasis. (626274)
1978
31
Mebendazole in the treatment of severe symptomatic trichuriasis in children. (848642)
1977
32
Algorithms in the diagnosis and management of exotic diseases. IX. Trichuriasis. (1245771)
1976
33
Experiencw with bitoscanate in hookworm disease and trichuriasis in Mexico. (769064)
1975
34
Diphetarsone in trichuriasis. (4814638)
1974
35
Study of oxyuriasis, trichuriasis in children and evaluation of mebendazole. (4426672)
1974
36
Clinical trichuriasis produced experimentally in growing pigs. II. Anthelmintic efficacy of dichlorvos. (4519451)
1973
37
Prevalence of human ascariasis and trichuriasis in San Juan and vicinity, Puerto Rico. (4711667)
1973
38
Trial of thiabendazole and viprynium embonate in combination for trichuriasis in aboriginal children. (4773610)
1973
39
Erythrocyte life span and hemoglobin levels in mouse trichuriasis. (5102816)
1971
40
Clinical trichuriasis in hospitalised Kuala Lumpur children. (4258570)
1971
41
Dichlorvos: an anthelmintic for primate trichuriasis. (4249649)
1970
42
Rectal prolapse in children with trichuriasis. (5980975)
1966
43
THE THERAPY OF TRICHURIASIS WITH A COMBINATION OF THIABENDAZOLE AND PYRVINIUM PAMOATE. (14317649)
1965
44
STILBAZIUM IODIDE (MONOPAR) IN THE TREATMENT OF HUMAN TRICHURIASIS. (14336083)
1965
45
STUDIES ON THE THERAPEUTIC EFFECTS OF THIABENDAZOLE (MK-360) AGAINST ASCARIASIS, TRICHURIASIS, STRONGYLOIDIASIS AND HOOKWROM INFECTION IN MAN. (14206516)
1964
46
Experimental trichuriasis. I. Antagonism between Trichuris muris and Aspiculuris tetraptera in the albino mouse. (13752159)
1961
47
Effect of dithiazanine in ascariasis, trichuriasis, enterobiasis and ankylostomiasis. (13924257)
1961
48
Dithiazanine, an effective broad-spectrum anthelmintic; results of therapy of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. (13480859)
1957
49
The severity of trichuriasis among children in Costa Rica. (13406571)
1957
50
Experiments in the therapy of human trichuriasis and hookworm disease. (13327189)
1956

Genetic Variations for Trichuriasis

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Expression for genes affiliated with Trichuriasis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Trichuriasis

Search GEO for disease gene expression data for Trichuriasis.

Pathways for genes affiliated with Trichuriasis

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Compounds for genes affiliated with Trichuriasis

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GO Terms for genes affiliated with Trichuriasis

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16Gene Ontology
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Biological processes related to Trichuriasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of release of cytochrome c from mitochondriaGO:09020010.1HRK, MFF
2chemotaxisGO:0069359.7RNASE2, PROK2, CCL23

Products for genes affiliated with Trichuriasis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Trichuriasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet