MCID: TRC062
MIFTS: 41

Tricuspid Atresia malady

Rare diseases, Cardiovascular diseases, Fetal diseases categories
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Summaries for Tricuspid Atresia

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Sources:
65Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:65 Tricuspid atresia is a form of congenital heart disease whereby there is a complete absence of the... more...

MalaCards: Tricuspid Atresia, also known as congenital agenesis of the tricuspid valve, is related to tetralogy of fallot and ventricular septal defect. An important gene associated with Tricuspid Atresia is ZFPM2 (zinc finger protein, FOG family member 2), and among its related pathways is Hemostasis. Affiliated tissues include heart, lung and liver, and related mouse phenotypes are liver/biliary system and mortality/aging.

Description from OMIM:47 605067

Aliases & Classifications for Tricuspid Atresia

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43NIH Rare Diseases, 49Orphanet, 47OMIM, 59SNOMED-CT via Orphanet, 36MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Fetal diseases
Anatomical: Cardiovascular diseases


Characteristics (Orphanet epidemiological data):

49
tricuspid atresia:
Inheritance: Sporadic; Prevalence: 1-9/100000; Age of onset: Neonatal/infancy


Aliases & Descriptions:

tricuspid atresia 43 49 47
congenital agenesis of the tricuspid valve 43


External Ids:

SNOMED-CT via Orphanet59 253455004, 63042009
OMIM47 605067
MESH via Orphanet36 D018785
ICD10 via Orphanet26 Q22.4
UMLS via Orphanet63 C0243002

Related Diseases for Tricuspid Atresia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Tricuspid Atresia:



Diseases related to tricuspid atresia

Symptoms for Tricuspid Atresia

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47OMIM
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Clinical features from OMIM:

605067

Drugs & Therapeutics for Tricuspid Atresia

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Tricuspid Atresia

Search NIH Clinical Center for Tricuspid Atresia

Genetic Tests for Tricuspid Atresia

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Anatomical Context for Tricuspid Atresia

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33MalaCards
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MalaCards organs/tissues related to Tricuspid Atresia:

33
Heart, Lung, Liver, Atrioventricular node

Animal Models for Tricuspid Atresia or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Tricuspid Atresia:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.5ALB, HEY2, ZFPM2
2MP:00107688.5ALB, HEY2, ZFPM2
3MP:00053698.4ALB, HEY2, ZFPM2
4MP:00053768.2ZFPM2, HEY2, ALB

Publications for Tricuspid Atresia

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52PubMed
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Articles related to Tricuspid Atresia:

(show top 50)    (show all 416)
idTitleAuthorsYear
1
Percutaneous transluminal pulmonary valvuloplasty in a child with tricuspid atresia, ventricular septal defect, and severe pulmonary valve stenosis: Usefulness of the Femoral Artery Approach. (24030841)
2013
2
eReply. Re: Balancing the pulmonary circulation in tricuspid atresia with an aortopulmonary window. (23868969)
2013
3
Left juxtaposed atrial appendages in a patient with dextrocardia and tricuspid atresia: TEE images. (21636938)
2011
4
Fenestrated exclusion of the right ventricle for tricuspid atresia and absent pulmonary valve. (20667372)
2010
5
Conduit from hypoplastic right ventricle to pulmonary artery in tricuspid atresia. (18245715)
2008
6
Tricuspid atresia with normal axis on ECG palliated with a central shunt; a case report. (19048769)
2008
7
Characteristics of Doppler myocardial echocardiography in patients with tricuspid atresia after total cavopulmonary connection with preserved systolic ventricular function. (16859773)
2007
8
Outcome of patients with double-inlet left ventricle or tricuspid atresia with transposed great arteries. (14715192)
2004
9
Tricuspid atresia associated with common arterial trunk and 22q11 chromosome deletion. (14959451)
2003
10
Tricuspid atresia--profile and outcome. (11717697)
2001
11
Tricuspid Atresia. (11096554)
2000
12
Operative treatment of truncus arteriosus communis coexisting with tricuspid atresia. (10654536)
2000
13
Myoarchitecture and connective tissue in hearts with tricuspid atresia. (9922357)
1999
14
Divided left atrium in association with tricuspid atresia and discordant ventriculo-arterial connections. (10323543)
1999
15
The long-term clinical outcome of patients with tricuspid atresia. II. Influence of surgical procedures. (1708394)
1991
16
Spectrum of tricuspid atresia--a study of 23 cases. (1752611)
1991
17
Tricuspid atresia. Surgical treatment, pediatric nursing care. (2288582)
1990
18
Tricuspid atresia with transposition of the great arteries in adolescents and adults: current state and late complications. (3342144)
1988
19
Tricuspid atresia versus other complex lesions. Comparison of results with a modified Fontan procedure. (3398542)
1988
20
Repair of tricuspid atresia: utility of right ventricular incorporation. (3355280)
1988
21
Fetal echocardiography: the prenatal diagnosis of tricuspid atresia (type Ic) during the second trimester of pregnancy. (3149959)
1987
22
Left ventricular function in tricuspid atresia: a radionuclide study. (3760364)
1986
23
Growth and function of the right ventricular outflow tract after Fontan's procedure for tricuspid atresia: a two-dimensional echocardiographic study. (2429391)
1986
24
Radionuclide measurement of left ventricular ejection fraction in tricuspid atresia. (6498034)
1984
25
Pregnancy in patients with tricuspid atresia. (6596958)
1984
26
Prolonged survival in tricuspid atresia with Eisenmenger's physiology. (6488600)
1984
27
Tricuspid atresia with overriding imperforate tricuspid membrane: an anatomic variant. (6500750)
1984
28
Left to right atrial shunting in tricuspid atresia. (6830668)
1983
29
Severe tricuspid stenosis presenting as tricuspid atresia. Echocargraphic diagnosis and surgical management. (7126391)
1982
30
Tricuspid atresia with persistent truncus arteriosus. (7471873)
1981
31
Aneurysm of the interatrial septum causing pulmonary venous obstruction in an infant with tricuspid atresia. (7282526)
1981
32
Successful surgical correction in two patients with tricuspid atresia using autologous pericardial valve-bearing tube graft. (7358777)
1980
33
Experience in palliative treatment of univentricular heart including tricuspid atresia. (87362)
1979
34
Simulated tricuspid valve echoes in tricuspid atresia. (655090)
1978
35
Anatomic variations in underdeveloped right ventricle related to tricuspid atresia and stenosis. (957756)
1976
36
Tricuspid atresia with christmas disease (hemophilia B). Report of a case. (1117747)
1975
37
Surgical palliation of tricuspid atresia. (1157283)
1975
38
Tricuspid atresia. An anatomical study of 17 cases. (1193117)
1975
39
Remote delayed ligation of vena cava in palliative surgery of tricuspid atresia. A Modification of the Glenn procedure. (4130542)
1974
40
Long-time observations of the Blalock-Taussig operation. IV. Tricuspid atresia. (4691169)
1973
41
Surgical repair of tricuspid atresia. (5089489)
1971
42
Tricuspid atresia, transposition, and coatation of the aorta. (4250022)
1970
43
Changing clinical features in tricuspid atresia without transposition of great vessels. Report of two cases. (5314675)
1969
44
Morphological studies in tricuspid atresia. (5697694)
1968
45
PARTIAL ECTOPIA CORDIS SIMULATING TRICUSPID ATRESIA: REPORT OF CASE. (14346185)
1965
46
TRICUSPID ATRESIA: A STEP TOWARD CORRECTIVE TREATMENT. (14113172)
1964
47
Tricuspid atresia. An electrocardiographic study. (13915106)
1962
48
Congenital tricuspid atresia; report of two cases. (13636625)
1959
49
Observations on 26 infants under one year of age operated on for tetralogy of Fallot or tricuspid atresia. (14827636)
1951
50
Congenital tricuspid atresia. (21032046)
1936

Variations for Tricuspid Atresia

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Expression for genes affiliated with Tricuspid Atresia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tricuspid Atresia

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Pathways for genes affiliated with Tricuspid Atresia

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50PathCards, 55Reactome
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Pathways related to Tricuspid Atresia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0ALB, ZFPM2

Compounds for genes affiliated with Tricuspid Atresia

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GO Terms for genes affiliated with Tricuspid Atresia

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16Gene Ontology
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Cellular components related to Tricuspid Atresia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056549.3HEY2, ZFPM2

Biological processes related to Tricuspid Atresia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ventricular septum morphogenesisGO:0604129.4HEY2, ZFPM2
2vasculogenesisGO:0015709.4HEY2, ZFPM2
3negative regulation of transcription, DNA-templatedGO:0458929.3HEY2, ZFPM2
4positive regulation of transcription from RNA polymerase II promoterGO:0459449.3HEY2, ZFPM2
5negative regulation of transcription from RNA polymerase II promoterGO:0001229.0HEY2, ZFPM2
6blood coagulationGO:0075968.9ZFPM2, ALB

Molecular functions related to Tricuspid Atresia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription factor bindingGO:0081349.3HEY2, ZFPM2

Products for genes affiliated with Tricuspid Atresia

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  • Antibodies
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Sources for Tricuspid Atresia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet