Trigeminal Neuralgia malady

MedlinePlus:³⁴ Trigeminal neuralgia (tn) is a type of chronic pain that affects your face. it causes extreme, sudden burning or shock-like pain. it usually affects one side of the face. any vibration on your face, even from talking, can set it off. the condition may come and go, disappearing for days or even months. but the longer you have it, the less often it goes away. tn usually affects people over 50, especially women. the cause is probably a blood vessel pressing on the trigeminal nerve, one of the largest nerves in the head. tumors and multiple sclerosis can also cause tn, but in some cases the cause is unknown. there is no single test to diagnose tn. it can be hard to diagnose, since many other conditions can cause facial pain. treatment options include medicines, surgery, and complementary techniques. nih: national institute of neurological disorders and stroke

MalaCards: Trigeminal Neuralgia, also known as tic douloureux, is related to hemifacial spasm and n syndrome. An important gene associated with Trigeminal Neuralgia is BMP2 (bone morphogenetic protein 2), and among its related pathways are Sodium channels and transporters: inward current and G-Beta Gamma Signaling. The drugs tocainide and tocainide monohydrochloride and the compounds saxitoxin and Lacosamide have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and skin, and related mouse phenotypes are cardiovascular system and behavior/neurological.

NIH Rare Diseases:⁴³ Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. the pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of the face), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor.  in some cases, the cause is unknown. treatment options include medicines, surgery, and complementary approaches.   last updated: 9/17/2010

NINDS:⁴⁴ Trigeminal neuralgia (TN), also called , is a chronic pain condition that causes extreme, sporadic, sudden burning or shock-like face pain.

Wikipedia:⁶⁴ Trigeminal neuralgia (TN, or TGN), also known as prosopalgia, or Fothergill\'s disease is a neuropathic... more...

Description from OMIM:⁴⁷ 190400

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Disease Ontology8 DOID:12098 MeSH35 D014277 ICD9CM27 350.1 OMIM47 190400 MESH via Orphanet36 D014277 SNOMED-CT57 322769008, 193090007, 31681005 155066002, more

ICD10 via Orphanet26 G50.0 SNOMED-CT via Orphanet58 31681005 UMLS via Orphanet62 C0040997 ICD1025 G50.0 UMLS61 C0040997

Clinical features from OMIM:

190400

Clinical synopsis from OMIM:

190400

Search GEO for disease gene expression data for Trigeminal Neuralgia.