MCID: TRG002
MIFTS: 57

Trigeminal Neuralgia malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Trigeminal Neuralgia

About this section
Sources:
11Disease Ontology, 13DISEASES, 27GTR, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 38MedlinePlus, 39MeSH, 40MESH via Orphanet, 48NIH Rare Diseases, 49NINDS, 50Novoseek, 52OMIM, 54Orphanet, 62SNOMED-CT, 64The Human Phenotype Ontology, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Trigeminal Neuralgia:

Name: Trigeminal Neuralgia 52 11 48 49 54 50 38 39 13 68 27
Tic Douloureux 48 49
Trigeminal Neuralgia Nos 11
 
Trifacial Neuralgia 11
Trifocal Neuralgia 11

Characteristics:

HPO:

64
trigeminal neuralgia:
Inheritance: autosomal dominant inheritance

Classifications:



External Ids:

OMIM52 190400
Disease Ontology11 DOID:12098
ICD1030 G50.0
ICD9CM32 350.1
MeSH39 D014277
Orphanet54 ORPHA221091
MESH via Orphanet40 D014277
UMLS via Orphanet69 C0040997
ICD10 via Orphanet31 G50.0

Summaries for Trigeminal Neuralgia

About this section
NINDS:49 Trigeminal neuralgia (TN), also called tic douloureux, is a chronic pain condition that causes extreme, sporadic, sudden burning or shock-like face pain. The pain seldom lasts more than a few seconds or a minute or two per episode. The intensity of pain can be physically and mentally incapacitating. TN pain is typically felt on one side of the jaw or cheek. Episodes can last for days, weeks, or months at a time and then disappear for months or years. In the days before an episode begins, some patients may experience a tingling or numbing sensation or a somewhat constant and aching pain. The attacks often worsen over time, with fewer and shorter pain-free periods before they recur. The intense flashes of pain can be triggered by vibration or contact with the cheek (such as when shaving, washing the face, or applying makeup), brushing teeth, eating, drinking, talking, or being exposed to the wind. TN occurs most often in people over age 50, but it can occur at any age, and is more common in women than in men. There is some evidence that the disorder runs in families, perhaps because of an inherited pattern of blood vessel formation. Although sometimes debilitating, the disorder is not life-threatening. The presumed cause of TN is a blood vessel pressing on the trigeminal nerve in the head as it exits the brainstem. TN may be part of the normal aging process but in some cases it is the associated with another disorder, such as multiple sclerosis or other disorders characterized by damage to the myelin sheath that covers certain nerves.

MalaCards based summary: Trigeminal Neuralgia, also known as tic douloureux, is related to glossopharyngeal neuralgia and hemifacial atrophy, progressive, and has symptoms including back pain, back pain and facial pain. An important gene associated with Trigeminal Neuralgia is SCN9A (Sodium Voltage-Gated Channel Alpha Subunit 9), and among its related pathways are Neuroscience and Cardiac conduction. The drugs carbamazepine and baclofen have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and skin, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and behavior/neurological.

NIH Rare Diseases:48 Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. the pain lasts a few seconds to a few minutes, and usually on only one side of the face. it can also cause muscle spasms in the face the same time as the pain. the pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of the face), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor or cyst. in some cases, the cause is unknown. treatment options include medicines, surgery, and complementary approaches. last updated: 2/17/2016

MedlinePlus:38 Trigeminal neuralgia (tn) is a type of chronic pain that affects your face. it causes extreme, sudden burning or shock-like pain. it usually affects one side of the face. any vibration on your face, even from talking, can set it off. the condition may come and go, disappearing for days or even months. but the longer you have it, the less often it goes away. tn usually affects people over 50, especially women. the cause is probably a blood vessel pressing on the trigeminal nerve, one of the largest nerves in the head. tumors and multiple sclerosis can also cause tn, but in some cases the cause is unknown. there is no single test to diagnose tn. it can be hard to diagnose, since many other conditions can cause facial pain. treatment options include medicines, surgery, and complementary techniques. nih: national institute of neurological disorders and stroke

Wikipedia:71 Trigeminal neuralgia (TN or TGN) is a chronic pain disorder that affects the trigeminal nerve. There are... more...

Description from OMIM:52 190400

Related Diseases for Trigeminal Neuralgia

About this section

Diseases related to Trigeminal Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1glossopharyngeal neuralgia11.4
2hemifacial atrophy, progressive11.0
3epidermoid brain tumor11.0
4trigeminal trophic syndrome11.0
5hemifacial spasm10.4
6arteriovenous malformation10.1
7headache10.1
8chronic eosinophilic pneumonia10.1ESR1, SLC6A4
9hydrocephalus10.0
10arachnoiditis10.0
11cerebellopontine angle tumor10.0
12persistent idiopathic facial pain10.0
13leprosy9.9
14arteriovenous fistula9.9
15burns9.9
16arachnoid cysts9.9
17cavernous malformation9.9
18systemic scleroderma9.9BMP2, ESR1
19charcot-marie-tooth disease, axonal, type 2h9.9SCN10A, SCN11A
20apodia, unilateral9.9SCN10A, SCN11A, SCN9A
21paroxysmal extreme pain disorder9.9SCN10A, SCN11A, SCN9A
22febrile seizures, familial, 3b9.8SCN10A, SCN11A, SCN9A
23auriculocondylar syndrome 19.8SCN10A, SCN11A, SCN9A
24temporal arteritis9.8
25sinusitis9.8
26lymphoma9.8
27meningoencephalitis9.8
28petrositis9.8
29choroiditis9.8
30burning mouth syndrome9.8
31petroclival meningioma9.8
32neuropathy9.8
33glioma9.8
34paroxysmal hemicrania9.8
35aneurysm9.8
36chronic pain9.8
37generalized epilepsy with febrile seizures plus9.8SCN10A, SCN11A, SCN9A
38rheumatoid arthritis9.7
39systemic lupus erythematosus9.7
40dandy-walker syndrome9.7
41achondroplasia9.7
42marfan syndrome9.7
43choroid plexus papilloma9.7
44pancreatic cancer9.7
45lipoma9.7
46cerebellar hypoplasia9.7
47arthritis9.7
48charcot-marie-tooth disease9.7
49chronic inflammatory demyelinating polyneuropathy9.7
50hematopoietic stem cell transplantation9.7

Comorbidity relations with Trigeminal Neuralgia via Phenotypic Disease Network (PDN):


Hypertension, EssentialMultiple Sclerosis, Disease Progression, Modifier of
Acute CystitisGlossopharyngeal Neuralgia
Hypothyroidism

Graphical network of the top 20 diseases related to Trigeminal Neuralgia:



Diseases related to trigeminal neuralgia

Symptoms & Phenotypes for Trigeminal Neuralgia

About this section

Symptoms by clinical synopsis from OMIM:

190400

Clinical features from OMIM:

190400

Human phenotypes related to Trigeminal Neuralgia:

 64
id Description HPO Frequency HPO Source Accession
1 trigeminal neuralgia64 HP:0100661

UMLS symptoms related to Trigeminal Neuralgia:


back pain, facial pain, headache, neuralgia, pain, sciatica, seizures, syncope, tremor, chronic pain, atypical facial pain, orofacial pain, vertigo/dizziness, sleeplessness

GenomeRNAi Phenotypes related to Trigeminal Neuralgia according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.7MBD1, SCN11A, SLC6A4

MGI Mouse Phenotypes related to Trigeminal Neuralgia according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.0CRLF1, ESR1, MBD1, SCN10A, SCN11A, SCN3A
2MP:00036316.9BMP2, CRLF1, ESR1, MBD1, SCN10A, SCN11A

Drugs & Therapeutics for Trigeminal Neuralgia

About this section

Drugs for Trigeminal Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 111)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dexamethasoneapproved, investigational, vet_approvedPhase 4217150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
2
LumefantrineapprovedPhase 414882186-77-46437380
Synonyms:
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha((dibutylamino)methyl)fluorene-4-methanol
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
(±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol
120583-69-9
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol
2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol
82186-77-4
AC-4542
AC1O5NKD
Benflumetol
Bio-0132
C30H32Cl3NO
 
CHEBI:156095
CHEMBL38827
CID6437380
Coartem
D03821
DB06708
HSDB 7210
I14-7746
LS-177674
Lumefantrine
Lumefantrine (INN)
Lumefantrine [INN:BAN]
MolPort-006-394-826
NCGC00167490-01
UNII-F38R0JR742
dl-Benflumelol
3
ArtemetherapprovedPhase 415071963-77-4119380, 68911
Synonyms:
( )-alpha-Artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin
(3alpha,5abeta,6beta,8abeta,9alpha,10beta,12beta,12aR*)-isomer of artemether
(3r,5as,6r,8as,9r,10r,12r,12ar)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
(5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
.beta.-Artemether
.beta.-Dihydroartemisinin methyl ether
.beta.-Methylether of 11-epi-dihydroartemisinin
10-Methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
159573-83-8
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-tri
71939-51-0
71963-77-4
74784-06-8
80286-56-2
93787-85-0
AC1L2APD
AC1L2XO8
AC1L9SH2
AC1L9UV0
AC1MI2ZX
AC1Q6Z74
AC1Q6Z7V
AR-1A4424
Arteannuin ether
Artemetero
Artemetero [INN-Spanish]
Artemether
Artemether (INN)
Artemether [INN]
Artemetheri
Artemetherum
Artemetherum [INN-Latin]
Artemisininelactol methyl ether
Artemos
Artenam
Artesaph
Artesian
Artimist
Artmether
BRN 5948416
C16H26O5
CHEBI:195280
 
CHEMBL411864
CHEMBL512315
CID10266705
CID104888
CID3062122
CID456408
CID500199
CID6483308
CID6712286
CID68911
CID9796294
CID9796295
CPD000469218
D02483
DB06697
Dihydroartemisinin methyl ether
Dihydroqinghaosu methyl ether
Dihydroquinghaosu methyl ether
Falcidol
Gvither
HMS2052L09
HSDB 7456
I06-0205
KST-1A8041
LS-176935
LS-64237
MLS001424249
Malartem
Methyl-dihydroartemisinine
NCI60_022891
NSC 665970
NSC665970
O-Methyldihydroartemisinine
Paluther
S2264_Selleck
SAM001246799
SM 224
SM 229
SM-224
SMR000469218
UNII-C7D6T3H22J
alpha-Artemether
alpha-Dihydroartemisinin methyl ether
artemether, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12aR*))-isomer
artemether[inn]
beta-Artemether
beta-Dihydroartemisinin methyl ether
rither
4
Triamcinoloneapproved, vet_approvedPhase 4510124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
5
Bupivacaineapproved, investigationalPhase 4, Phase 2, Phase 312332180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
6
Miconazoleapproved, investigational, vet_approvedPhase 4370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
7
Ketamineapproved, vet_approvedPhase 45696740-88-13821
Synonyms:
(+-)-Ketamine
(+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-Ketamine
(-)-Ketamine
(S)-(-)-Ketamine
(S)-Ketamine
(±)-ketamine
100477-72-3
2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone
33643-45-7
6740-88-1
79499-51-7
AC1L1GSH
AC1Q40UR
AKOS001053247
BRN 2216965
C07525
C13H16ClNO
CHEBI:138833
CHEBI:6121
CHEMBL742
CI 581 base
CI-581
CID3821
CLSTA 20
Calypsol
Cetamina
Cetamina [INN-Spanish]
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)- (9CI)
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (9CI)
Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)- (8CI)
D08098
DB01221
 
DEA No. 7285
DL-ketamine
DivK1c_000217
EINECS 229-804-1
Esketamine
Green
IDI1_000217
KBio1_000217
KETAMINE HCL
Ketaject
Ketalar
Ketalar base
Ketamina
Ketamine (INN)
Ketamine Base
Ketamine HCL
Ketamine [INN:BAN]
Ketaminum
Ketaminum [INN-Latin]
Ketanest
Ketoject
Ketolar
Kétamine
L-Ketamine
LS-57301
MLS001331674
MolPort-001-838-070
NCGC00159480-02
NCGC00159480-03
NINDS_000217
NMDA
NSC 70151
NSC70151
SMR000238141
Special K
Special K [street name]
T385
Tekam
Tekam (TN)
UNII-690G0D6V8H
dl-Ketamine
ketamine
l-Ketamine
8
OndansetronapprovedPhase 432699614-02-54595
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9 (mono-hydrochloride dihydrate)
108303-49-7
116002-70-1
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4 (mono-hydrochloride)
99614-02-5
AB00373674
AC1L1IIM
AKOS000599484
Apo-ondansetron
BAS 00717177
BPBio1_001118
BRD-A19736161-001-01-8
BRD-A19736161-003-03-0
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
CHEMBL46
CID4595
CPD001307702
D00456
DB00904
DESMETHYLONDANSETRON
GR 38032
GR 38032X
GR-38032F
GR38032F
HMS2090H16
I06-0687
I06-1329
 
L000456
LS-172305
LS-51878
MolPort-001-944-253
NCI60_022780
Novo-ondansetron
Ondansetron
Ondansetron (JAN/USP/INN)
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
PHL-ondansetron
PMS-ondansetron
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
Ratio-ondansetron
SAM002589958
SN-307
SPBio_002938
STK370548
STOCK4S-10990
Sandoz ondansetron
TL8006071
TimTec1_001750
UNII-4AF302ESOS
ZOFRAN IN PLASTIC CONTAINER
Zofran
Zofran ODT
Zofran ODT (TN)
Zofran odt
Zophren
Zudan
ondansetron
ondansetron (Zofran)
9
Sufentanilapproved, investigationalPhase 418556030-54-741693
Synonyms:
56030-54-7
60561-17-3 (citrate)
AC1L26AJ
AC1Q5I7B
C08022
C22H30N2O2S
CHEBI:127638
CHEBI:9316
CHEMBL658
CID41693
Chronogesic
D05938
DB00708
HSDB 6760
L000580
LS-175693
MolPort-004-286-008
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide
 
N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide
N-{4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
N-{4-[(methyloxy)methyl]-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
Oprea1_120838
Oprea1_246787
PDSP1_001741
PDSP2_001724
R 30730
R-30730
SUFENTANIL
Sufentanil
Sufentanil (USAN/INN)
Sufentanil Citrate
Sufentanil [USAN:BAN:INN]
Sufentanilo
Sufentanilum
Sufentanilum [INN-Latin]
Sufentanyl
Sulfentanil
Sulfentanyl
UNII-AFE2YW0IIZ
10
RopivacaineapprovedPhase 479384057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
11Antiparasitic AgentsPhase 42199
12Antiprotozoal AgentsPhase 42051
13AntimalarialsPhase 41246
14Excitatory Amino Acid AntagonistsPhase 4, Phase 2, Phase 31347
15AnthelminticsPhase 4446
16Antifungal AgentsPhase 43696
17Anti-Infective AgentsPhase 422062
18ArtemisininePhase 4289
19Psychotropic DrugsPhase 4, Phase 2, Phase 36430
20AnalgesicsPhase 4, Phase 2, Phase 311733
21Tranquilizing AgentsPhase 4, Phase 2, Phase 34265
22Triamcinolone hexacetonidePhase 4510
23ArtemisininsPhase 4289
24Neurotransmitter AgentsPhase 4, Phase 2, Phase 3, Phase 118340
25Artemether-lumefantrine combinationPhase 4141
26triamcinolone acetonidePhase 4510
27Autonomic AgentsPhase 410150
28BB 1101Phase 42171
29Central Nervous System DepressantsPhase 4, Phase 2, Phase 313403
30Dexamethasone 21-phosphatePhase 42171
31Antineoplastic Agents, HormonalPhase 45592
32Anti-Inflammatory AgentsPhase 410729
33AnestheticsPhase 4, Phase 2, Phase 39596
34Anesthetics, LocalPhase 4, Phase 2, Phase 33492
35AntiemeticsPhase 44022
36Dexamethasone acetatePhase 421711177-87-3
37Gastrointestinal AgentsPhase 48402
38Immunosuppressive AgentsPhase 413086
39Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 123689
40
protease inhibitorsPhase 45471
Synonyms:
 
protease inhibitors
41Excitatory Amino AcidsPhase 4, Phase 2, Phase 31362
42Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
43HormonesPhase 414415
44HIV Protease InhibitorsPhase 45470
45Triamcinolone diacetatePhase 4510
46Hormone AntagonistsPhase 413180
47glucocorticoidsPhase 45103
48Serotonin AgentsPhase 43156
49
SerotoninPhase 4362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
50Anti-Anxiety AgentsPhase 4, Phase 21885

Interventional clinical trials:

(show top 50)    (show all 54)
idNameStatusNCT IDPhase
1Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia PainCompletedNCT01447108Phase 4
2Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial PainCompletedNCT02024724Phase 4
3A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)CompletedNCT01256658Phase 4
4Postoperative Analgesia in Patients With Microvascular DecompressionNot yet recruitingNCT03152955Phase 4
5Efficacy and Safety Study of Lamotrigine to Treat Trigeminal NeuralgiaCompletedNCT00913107Phase 2, Phase 3
6Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate SurgeryCompletedNCT02923869Phase 2, Phase 3
7Efficacy and Safety Study of BIIB074 in Participants With Trigeminal NeuralgiaNot yet recruitingNCT03070132Phase 3
8A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal NeuralgiaTerminatedNCT01364259Phase 3
9CONCEPT: Crossover Efficacy Pain Trial in Motor Cortex Stimulation for Intractable Neuropathic PainTerminatedNCT00122915Phase 3
10Transcranial Magnetic Stimulation (TMS) Effects on Pain PerceptionWithdrawnNCT00349050Phase 2, Phase 3
11Efficacy and Safety of ATNC05 in Treatment of Atypical Facial PainWithdrawnNCT01920087Phase 2, Phase 3
12Clinical Trial of Hyperbaric Oxygen Treatment in Trigeminal Neuralgia PatientsUnknown statusNCT00866424Phase 1, Phase 2
13A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal NeuralgiaCompletedNCT01540630Phase 2
14Studies of Dextromethorphan and Topiramate to Treat Oral and Facial PainCompletedNCT00001725Phase 2
15Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal NeuralgiaRecruitingNCT02473016Phase 2
16Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical TechniqueRecruitingNCT02624661Phase 1, Phase 2
17Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Trigeminal Neuralgia. Safety Issues.RecruitingNCT02662972Phase 1, Phase 2
18Interest of Pregabalin (Lyrica) on the Treatment of Reflex Earache in Head and Neck Cancer.RecruitingNCT02924675Phase 2
19Botulinum Toxin for the Treatment of Trigeminal NeuralgiaTerminatedNCT02088632Phase 2
20Civamide Nasal Solution for Postherpetic Neuralgia of the Trigeminal NerveTerminatedNCT01886313Phase 2
21Transcranial Stimulation (tDCS) For the Treatment of Neuropathic Facial PainTerminatedNCT01849796Phase 2
22PK & Tolerability of CNV1014802 in Young and Elderly Healthy VolunteersUnknown statusNCT02359344Phase 1
23PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian ParticipantsCompletedNCT02831517Phase 1
24New Formulation and Food Effect Study of BIIB074CompletedNCT02951221Phase 1
25Study of Integrity of Down Inhibitor Bundle at Patients Suffering of Neuropathic PainCompletedNCT01053845Phase 1
26Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.RecruitingNCT02321566Phase 1
27Transcranial Magnetic Stimulation for Facial PainRecruitingNCT02633306Phase 1
28A Study of Patient Reported Outcomes After Stereotactic Radiosurgical Rhizotomy for Trigeminal NeuralgiaUnknown statusNCT01364285
29Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal NeuralgiaUnknown statusNCT01364272
30Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve InjuryUnknown statusNCT01586598
31Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal NeuralgiaCompletedNCT00203229
32Randomized Study of L-Baclofen in Patients With Refractory Trigeminal NeuralgiaCompletedNCT00004431
33The Effect of Intravenous Lidocaine on Trigeminal NeuralgiaCompletedNCT01955967
34EEG Monitoring to Assess Emergence From NeuroanesthesiaCompletedNCT00443807
35Hippocampal Radiation Exposure and MemoryCompletedNCT00603694
36A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot PainCompletedNCT00336349
37Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective StudyCompletedNCT03066037
38Brain as a Therapeutic and Research Target in Trigeminal Neuropathic PainCompletedNCT03003715
39Somatosensory Investigation of Orofacial Pain PatientsCompletedNCT02910336
40fMRI and DTI of Cerebellar Responses to Pain in the Human Trigeminal SystemCompletedNCT01738126
41Evaluation of Lamotrigine on Neuropathic Facial Pain Using fMRICompletedNCT00243152
42RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia RadiosurgeryRecruitingNCT02708810
43Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal NeuralgiaRecruitingNCT02427074
44An Evaluation of the Effect of a Surface Acoustic Wave Patch Device on the Symptons of Trigeminal NeuralgiaRecruitingNCT02801630
45The Will Erwin Headache Research Center - Cluster Headache StudyRecruitingNCT02910323
46An Follow-up Study of Occlusal Adjustment for Orofacial PainRecruitingNCT02856906
47Effect of Sumatriptan on the Postoperative Quality of Recovery After Elective Minimally Invasive CraniotomyRecruitingNCT01632657
48HBOT Late Radiation Tissue InjuryRecruitingNCT02425215
49The Efficacy of L-cysteine in Prevention of Cluster HeadacheRecruitingNCT02310828
50A Nasal Applicator for the Treatment of Trigeminal NeuralgiaActive, not recruitingNCT01761604

Search NIH Clinical Center for Trigeminal Neuralgia

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: trigeminal neuralgia

Genetic Tests for Trigeminal Neuralgia

About this section

Genetic tests related to Trigeminal Neuralgia:

id Genetic test Affiliating Genes
1 Trigeminal Neuralgia27

Anatomical Context for Trigeminal Neuralgia

About this section

MalaCards organs/tissues related to Trigeminal Neuralgia:

36
Brain, Testes, Skin, Trigeminal ganglion, Tongue, Breast, Liver

Publications for Trigeminal Neuralgia

About this section

Articles related to Trigeminal Neuralgia:

(show top 50)    (show all 699)
idTitleAuthorsYear
1
Nerve atrophy and a small trigeminal pontine angle in primary trigeminal neuralgia: A morphometric MRI study. (28532907)
2017
2
A rare presentation of trigeminal neuralgia in lateral medullary syndrome. (28488638)
2017
3
Trigeminal neuralgia. (28033174)
2017
4
A retrospective study of neurocombing for the treatment of trigeminal neuralgia without neurovascular compression. (28063126)
2017
5
Nerve Combing for Trigeminal Neuralgia Without Vascular Compression. (27875506)
2017
6
Symptomatic Trigeminal Neuralgia Caused by Cerebellopontine Angle Tumors. (28468211)
2017
7
Altered brain structure and function associated with sensory and affective components of classic trigeminal neuralgia. (28520647)
2017
8
Microvascular decompression is an effective therapy for trigeminal neuralgia due to dolichoectatic basilar artery compression: case reports and literature review. (28091827)
2017
9
An experimental animal model for percutaneous procedures used in trigeminal neuralgia. (28397136)
2017
10
Efficacy and Prognostic Value of Partial Sensory Rhizotomy and Microvascular Decompression for Primary Trigeminal Neuralgia: A Comparative Study. (28502974)
2017
11
The role of radiosurgery in trigeminal neuralgia. (28527088)
2017
12
Trigeminal neuralgia and neuropathy in large sporadic vestibular schwannomas. (28084915)
2017
13
Stereotactic Radiosurgery as Initial Surgical Management for Elderly Patients with Trigeminal Neuralgia. (28501876)
2017
14
Hydrocephalus and trigeminal neuralgia: exploring the association and management options. (28421829)
2017
15
Two times of trigeminal neuralgia resolution following hydrocephalus treatment in a patient with a high-voltage electric shock to his head: a case report and a review of the literature. (28429608)
2017
16
Proteomic Analysis of the Hippocampus in Mouse Models of Trigeminal Neuralgia and Inescapable Shock-Induced Depression. (28424990)
2017
17
The Study of Calcium, Phosphonium, Magnesium, and Ferrum Concentration in Serum of Patients With Primary Trigeminal Neuralgia. (28468201)
2017
18
Gamma Knife Radiosurgery for Idiopathic Trigeminal Neuralgia; does the status of offending vessels influence on pain control or side effects? (28532912)
2017
19
Computed Tomography in the Diagnosis of Classical Trigeminal Neuralgia. (28481804)
2017
20
Atypical Trigeminal Neuralgia: A Rare Neurological Manifestation of Systemic Lupus Erythematosus. (28077839)
2017
21
Meta-analysis on safety and efficacy of microsurgical and radiosurgical treatment of trigeminal neuralgia. (28435111)
2017
22
Trochlear Schwannoma Presenting with Isolated Trigeminal Neuralgia. (28434965)
2017
23
Trigeminal neuralgia - diagnosis and treatment. (28076964)
2017
24
Clinical analysis and surgical treatment of trigeminal neuralgia caused by vertebrobasilar dolichoectasia: A retrospective study. (28392449)
2017
25
The relationship of dose to nerve volume in predicting pain recurrence after stereotactic radiosurgery in trigeminal neuralgia. (28524797)
2017
26
Frameless stereotactic radiosurgery for the treatment of multiple sclerosis-related trigeminal neuralgia. (28454993)
2017
27
Carotid cavernous fistula after percutaneous balloon compression for trigeminal neuralgia: Endovascular treatment with coils. (28458950)
2017
28
Trigeminal Ganglioneuroma: A rare cause of trigeminal neuralgia caused by cerebello-pontine angle tumor. (28043883)
2016
29
Efficacy of stereotactic gamma knife surgery and microvascular decompression in the treatment of primary trigeminal neuralgia: a retrospective study of 220 cases from a single center. (27555796)
2016
30
Gamma knife radiosurgery for trigeminal neuralgia secondary to benign lesions. (27041354)
2016
31
New clinical and morphological aspects in trigeminal neuralgia. (27157289)
2016
32
Comparing Percutaneous Treatments of Trigeminal Neuralgia: 19 Years of Experience in a Single Centre. (27071078)
2016
33
Narrow Foramen Ovale and Rotundum: A Role in the Etiology of Trigeminal Neuralgia. (28005781)
2016
34
Drug-Induced Hypersensitivity Syndrome Caused by Carbamazepine Used for the Treatment of Trigeminal Neuralgia. (27885344)
2016
35
Surgical variation of microvascular decompression for trigeminal neuralgia: A technical note and anatomical study. (27625893)
2016
36
Hydrocephalus: an underrated long-term complication of microvascular decompression for trigeminal neuralgia. A single institute experience. (27522357)
2016
37
Letter to the Editor: Trigeminal neuralgia in patients with multiple sclerosis. (27203144)
2016
38
Symptomatic trigeminal neuralgia and nocturnal thunderclap headache resulting from a carotid paraganglioma. (27226004)
2016
39
Pterygopalatine fossa metastasis with severe trigeminal neuralgia from neuroendocrine carcinoma of the breast. (27209445)
2016
40
Trigeminal Neuralgia Induced by Sour and Spicy Foods: What Is the Underlying Mechanism? A Case Report. (27472530)
2016
41
Central antinociceptive activity of peripherally applied botulinum toxin type A in lab rat model of trigeminal neuralgia. (27104119)
2016
42
Microvascular decompression for trigeminal neuralgia secondary to vertebrobasilar dolichoectasia. Case report, literature review, and pooled case analysis. (27445080)
2016
43
Clinical features and long-term surgical outcomes in 39 patients withtumor-related trigeminal neuralgia compared with 360 patients with idiopathic trigeminal neuralgia. (27648861)
2016
44
Percutaneous trigeminal ganglion radiofrequency thermocoagulation alleviates anxiety and depression disorders in patients with classic trigeminal neuralgia: A cohort study. (27930513)
2016
45
Frameless Stereotactic Radiosurgery, a Feasible Alternative to the Frame-Based Technique for the Treatment of Refractory Trigeminal Neuralgia. (27186453)
2016
46
Percutaneous Glycerol Rhizotomy for Trigeminal Neuralgia Using a Single-Plane, Flat Panel Detector Angiography System: Technical Note. (27041633)
2016
47
A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia. (27533070)
2016
48
Imaging of Neurovascular Compression Syndromes: Trigeminal Neuralgia, Hemifacial Spasm, Vestibular Paroxysmia, and Glossopharyngeal Neuralgia. (26892985)
2016
49
A dual concurrent mechanism explains trigeminal neuralgia in patients with multiple sclerosis. (27895247)
2016
50
Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. (27093858)
2016

Variations for Trigeminal Neuralgia

About this section

Expression for genes affiliated with Trigeminal Neuralgia

About this section
Search GEO for disease gene expression data for Trigeminal Neuralgia.

Pathways for genes affiliated with Trigeminal Neuralgia

About this section

GO Terms for genes affiliated with Trigeminal Neuralgia

About this section

Cellular components related to Trigeminal Neuralgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:00015188.7SCN10A, SCN11A, SCN3A, SCN9A

Biological processes related to Trigeminal Neuralgia according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1sensory perception of painGO:001923310.6SCN10A, SCN9A
2odontogenesis of dentin-containing toothGO:004247510.4BMP2, SCN10A
3response to estradiolGO:003235510.0ESR1, MBD1, SLC6A4
4negative regulation of gene expressionGO:00106299.9BMP2, ESR1, MBD1
5ion transmembrane transportGO:00342209.8SCN11A, SCN3A, SCN9A
6response to drugGO:00424939.6MBD1, SCN11A, SLC6A4
7ion transportGO:00068119.5SCN10A, SCN11A, SCN3A, SCN9A
8membrane depolarization during action potentialGO:00860109.5SCN10A, SCN11A, SCN3A, SCN9A
9neuronal action potentialGO:00192289.5SCN10A, SCN11A, SCN3A, SCN9A
10regulation of ion transmembrane transportGO:00347659.5SCN10A, SCN11A, SCN3A, SCN9A
11regulation of postsynaptic membrane potentialGO:00600789.5SCN10A, SCN11A, SCN3A, SCN9A
12sodium ion transmembrane transportGO:00357259.4SCN10A, SCN11A, SCN3A, SCN9A
13sodium ion transportGO:00068149.4SCN10A, SCN11A, SCN3A, SCN9A
14transmembrane transportGO:00550858.4SCN10A, SCN11A, SCN3A, SCN9A, SLC6A4

Molecular functions related to Trigeminal Neuralgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ion channel activityGO:00052169.3SCN10A, SCN11A, SCN3A, SCN9A
2sodium channel activityGO:00052729.3SCN10A, SCN11A, SCN3A, SCN9A
3voltage-gated ion channel activityGO:00052449.1SCN10A, SCN11A, SCN3A, SCN9A
4voltage-gated sodium channel activityGO:00052488.7SCN10A, SCN11A, SCN3A, SCN9A

Sources for Trigeminal Neuralgia

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet