MCID: TRG006
MIFTS: 18

Trigger Thumb

Categories: Rare diseases

Aliases & Classifications for Trigger Thumb

MalaCards integrated aliases for Trigger Thumb:

Name: Trigger Thumb 50
Recurrent Trigger Thumb 50 69
Congenital Trigger Thumb 50
Bilateral Trigger Thumb 50

Classifications:



Summaries for Trigger Thumb

MalaCards based summary : Trigger Thumb, also known as recurrent trigger thumb, is related to arthritis and tenosynovitis. The drugs Lidocaine and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include brain.

Related Diseases for Trigger Thumb

Diseases related to Trigger Thumb via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 arthritis 9.8
2 tenosynovitis 9.6
3 madelung deformity 9.6

Symptoms & Phenotypes for Trigger Thumb

Drugs & Therapeutics for Trigger Thumb

Drugs for Trigger Thumb (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3 137-58-6 3676
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
3 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3
4 Anesthetics Phase 4
5 glucocorticoids Phase 4,Phase 2,Phase 3
6 Hormone Antagonists Phase 4,Phase 2,Phase 3
7 Hormones Phase 4,Phase 2,Phase 3
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
9 Anesthetics, Local Phase 4
10 Anti-Arrhythmia Agents Phase 4
11 Antiemetics Phase 4
12 Antineoplastic Agents, Hormonal Phase 4
13 Autonomic Agents Phase 4
14 BB 1101 Phase 4
15 Central Nervous System Depressants Phase 4
16 Dexamethasone 21-phosphate Phase 4
17 Dexamethasone acetate Phase 4 1177-87-3
18 Diuretics, Potassium Sparing Phase 4
19 Gastrointestinal Agents Phase 4
20 HIV Protease Inhibitors Phase 4
21 Peripheral Nervous System Agents Phase 4
22 Pharmaceutical Solutions Phase 4
23
protease inhibitors Phase 4
24 Sodium Channel Blockers Phase 4
25
Hyaluronic acid Approved, Vet_approved Phase 2, Phase 3 9004-61-9 53477741 24759
26
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
27 Adjuvants, Immunologic Phase 2, Phase 3
28 Immunosuppressive Agents Phase 2, Phase 3
29 Protective Agents Phase 2, Phase 3
30 triamcinolone acetonide Phase 2, Phase 3
31 Triamcinolone diacetate Phase 2, Phase 3
32 Triamcinolone hexacetonide Phase 2, Phase 3
33 Viscosupplements Phase 2, Phase 3
34
Cortisone acetate Approved 1950-04-4, 50-04-4 5745
35
Benzocaine Approved 1994-09-7, 94-09-7 2337
36
Menthol Approved 2216-51-5 16666
37
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
38
Rocuronium Approved 119302-91-9, 143558-00-3 441290
39 tannic acid Approved, Nutraceutical
40
Cortisone 53-06-5 222786
41 Hemostatics

Interventional clinical trials:

(show all 16)

id Name Status NCT ID Phase Drugs
1 Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture Terminated NCT02421419 Phase 4 Dexamethasone Sodium Phosphate;Xylocaine;Sodium Chloride
2 Efficacy of Ultrasound Guided Hyaluronic Injection in Treatment of Trigger Finger Recruiting NCT03131882 Phase 2, Phase 3 Hyaluronic Acid;Triamcinolone Acetonide
3 Ultrasound Guided A1 Pulley Release For The Treatment of Trigger Finger Active, not recruiting NCT02830672 Phase 2, Phase 3
4 Trigger Point Therapy Versus Manipulation Correcting Thoracic Manipulable Lesion Unknown status NCT01123226 Phase 2
5 Chronic Shoulder Pain Treated by Pressures With the Thumbs on the Trigger Points Completed NCT00679887 Phase 1, Phase 2
6 The Treatment of the Median Nerve for the Elimination of the Symptoms Associated With the Carpal Tunnel Syndrome Completed NCT00634738 Phase 1, Phase 2
7 The Treatment of Carpal Tunnel Syndrome Using Thumb Pressure Along the Median Nerve Completed NCT00634699 Phase 1, Phase 2
8 Study Comparing One Versus Two Cortisone Injections for Trigger Finger Unknown status NCT00951236 One cortisone injection;Two cortisone Injections
9 Time Effect of the Pressure Release Technique Application in the Latent Myofascial Trigger Points Completed NCT03006822
10 Effect of Dry Needling on Myofascial Trigger Point Completed NCT02107456
11 The Effects of Dry Needling & Kinesio Tape on Anterior Knee Pain Completed NCT02118246
12 Referred Pain Patterns Infraspinatus Muscle Completed NCT02817269
13 Electrical Stimulation to Improve Hand Function in Patients With Chronic Stroke Completed NCT00023569
14 Brain Function in Focal Dystonia Completed NCT00102999
15 Validation of the TOF Cuff Monitor® Which Measures Neuromuscular Block on the Upper Arm Recruiting NCT03256955
16 The Natural History of Congenital Trigger Thumbs Active, not recruiting NCT01424995

Search NIH Clinical Center for Trigger Thumb

Genetic Tests for Trigger Thumb

Anatomical Context for Trigger Thumb

MalaCards organs/tissues related to Trigger Thumb:

39
Brain

Publications for Trigger Thumb

Articles related to Trigger Thumb:

(show top 50) (show all 114)
id Title Authors Year
1
Trigger Thumb ( 28722884 )
2017
2
Quantitative Measurements of the Cross-sectional Configuration of the Flexor Pollicis Longus Tendon Using Ultrasonography in Patients With Pediatric Trigger Thumb. ( 28935339 )
2017
3
Developmental Trigger Thumb. ( 27064470 )
2016
4
Short-term Versus Long-term Outcomes After Open or Percutaneous Release for Trigger Thumb. ( 27783840 )
2016
5
Zhao L, Chen X, Zhang L. Digital necrosis after triamcinolone acetonide injection for trigger thumb: case report. J Hand Surg Eur. 2015, 40:741-2. ( 26879924 )
2016
6
Risk stratification for the recurrence of trigger thumb after surgical release in the paediatric patient. ( 27352865 )
2016
7
Concomitant Congenital Trigger Thumb and Thumb Aplasia. ( 26101009 )
2015
8
MR imaging findings of trigger thumb. ( 26028473 )
2015
9
Open surgery versus nonoperative treatments for paediatric trigger thumb: a systematic review. ( 24563498 )
2014
10
Delayed Case of Congenital Bilateral Trigger Thumb: A Case Report and Review of Literature. ( 27298940 )
2014
11
Results of surgical release in pediatric trigger thumb. ( 25365888 )
2014
12
A simple technique for confirmation of complete release in surgical treatment of pediatric trigger thumb. ( 25442753 )
2014
13
Flexor pollicis longus rupture in a trigger thumb after intrasheath triamcinolone injections: a case report with literature review. ( 25186581 )
2014
14
Avoiding digital nerve injury in paediatric trigger thumb release. ( 25350202 )
2014
15
Digital necrosis after triamcinolone acetonide injection for trigger thumb: case report. ( 25134719 )
2014
16
The treatment of trigger thumb in children: conservative or surgical? ( 24696931 )
2013
17
Serial ultrasound evaluation of pediatric trigger thumb. ( 23482269 )
2013
18
Percutaneous Trigger Thumb Release in Children: Neither Effective Nor Safe: A Cross-over Controlled Trial. ( 24322630 )
2013
19
Flexor pulley reconstruction after rupture following corticosteroid injections for trigger thumb: a case report. ( 24156592 )
2013
20
Open versus percutaneous release for the treatment of trigger thumb. ( 24093706 )
2013
21
Hand surface landmarks and measurements in the treatment of trigger thumb. ( 23591023 )
2013
22
Congenital trigger thumb in children: electron microscopy and immunohistochemical analysis of the first annular pulley. ( 22547147 )
2012
23
Varied anatomy of the thumb pulley system: implications for successful trigger thumb release. ( 23101525 )
2012
24
Percutaneous trigger thumb release with 18 guage needle. ( 23513471 )
2012
25
Management of pediatric trigger thumb and trigger finger. ( 22474090 )
2012
26
Conservative treatment of pediatric trigger thumb: follow-up for over 4 years. ( 22002508 )
2012
27
Digital artery pseudoaneurysm following percutaneous trigger thumb release: a case report. ( 22258013 )
2012
28
Acquired trigger thumb vs. congenital clasped thumb: recognize the difference: a case report. ( 23730240 )
2012
29
Efficacy of sonographically guided intra-flexoral sheath corticosteroid injection in the treatment of trigger thumb. ( 23268819 )
2012
30
Mirror-image trigger thumb in dichorionic identical twins. ( 22691680 )
2012
31
Pediatric trigger thumb with locked interphalangeal joint: can observation or splinting be a treatment option? ( 22955537 )
2012
32
Trigger thumb of the dominant hand in identical twins. ( 21099552 )
2011
33
The natural history of pediatric trigger thumb: a study with a minimum of five years follow-up. ( 21629478 )
2011
34
Surgical release of the pediatric trigger thumb. ( 21463727 )
2011
35
Sesamoid arthritis mimicking trigger thumb. ( 21410118 )
2011
36
Trigger thumb in children: results of surgical treatment in children above 5 years of age. ( 20864858 )
2010
37
Safe treatment of trigger thumb with longitudinal anatomic landmarks. ( 20862293 )
2010
38
Complete annular and partial oblique pulley release for pediatric locked trigger thumb. ( 22131924 )
2010
39
The effect of miniscalpel-needle versus steroid injection for trigger thumb release. ( 19675034 )
2009
40
Failure of differentiation: Part II (arthrogryposis, camptodactyly, clinodactyly, madelung deformity, trigger finger, and trigger thumb). ( 19380060 )
2009
41
Evaluation of pediatric trigger thumb in the Hispanic population at a southwest urban medical center. ( 19935306 )
2009
42
Fibrous flexor sheath ganglion and trigger thumb in a 14-year-old female. ( 19881040 )
2009
43
Surgical treatment of pediatric trigger thumb with metacarpophalangeal hyperextension laxity. ( 19727964 )
2009
44
Shower emboli and digital necrosis after a single corticosteroid injection for trigger thumb: case report. ( 19128892 )
2009
45
Long-term results of surgical release of trigger finger and trigger thumb in adults. ( 19125260 )
2009
46
Trigger thumb in children: current recommendations for treatment. ( 18656777 )
2008
47
The natural history of pediatric trigger thumb. ( 18451388 )
2008
48
Pediatric trigger thumb. ( 18762117 )
2008
49
Percutaneous release of trigger thumb: do we really need steroid? ( 17404732 )
2007
50
Percutaneous release of the trigger thumb: is it safe, cheap and effective? ( 16847643 )
2007

Variations for Trigger Thumb

Expression for Trigger Thumb

Search GEO for disease gene expression data for Trigger Thumb.

Pathways for Trigger Thumb

GO Terms for Trigger Thumb

Sources for Trigger Thumb

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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