Triple X Syndrome malady
Categories: Rare diseases, Reproductive diseases, Endocrine diseases, Fetal diseases
Aliases & Descriptions for Triple X Syndrome:
Orphanet epidemiological data:51
Inheritance: Not applicable; Age of onset: Childhood,Infancy; Age of death: normal life expectancy
Global: Rare diseases, Fetal diseases
Anatomical: Reproductive diseases, Endocrine diseases
Rare infertility disorders
Rare gynaecological and obstetric diseases
Rare endocrine diseases
Developmental anomalies during embryogenesis
NIH Rare Diseases:45 47 xxx syndrome, also called trisomy x or triple x syndrome, is characterized by the presence of an additional (third) x chromosome in each of a female's cells (which normally have two x chromosomes). an extra copy of the x chromosome is associated with tall stature, learning problems, and other features in some girls and women. seizures or kidney abnormalities occur in about 10 percent of affected females. 47 xxx syndrome is usually caused by a random event during the formation of reproductive cells (eggs and sperm). an error in cell division called nondisjunction can result in reproductive cells with an abnormal number of chromosomes. treatment typically focuses on specific symptoms, if present. some females with 47 xxx syndrome have an extra x chromosome in only some of their cells; this is called 46,xx/47,xxx mosaicism. last updated: 3/16/2016
MalaCards based summary: Triple X Syndrome, also known as trisomy x, is related to chromosome xq duplication and numeric sex chromosome variations, and has symptoms including abnormality of chromosome segregation, tall stature and epicanthus. An important gene associated with Triple X Syndrome is SHOX (Short Stature Homeobox). Affiliated tissues include kidney, eye and bone.
Genetics Home Reference:23 Triple X syndrome, also called trisomy X or 47,XXX, is characterized by the presence of an additional X chromosome in each of a female's cells. Although females with this condition may be taller than average, this chromosomal change typically causes no unusual physical features. Most females with triple X syndrome have normal sexual development and are able to conceive children.
Wikipedia:68 Triple X syndrome (also known as triplo-X, trisomy X, XXX syndrome, 47,XXX aneuploidy) is a form of... more...
Symptoms:51 (show all 18)
HPO human phenotypes related to Triple X Syndrome:(show all 17)
Drugs for Triple X Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show top 50) (show all 68)
Interventional clinical trials:(show all 14)
Search NIH Clinical Center for Triple X Syndrome
MalaCards organs/tissues related to Triple X Syndrome:33
Kidney, Eye, Bone, Breast, Prostate, Lung, Temporal lobe
Articles related to Triple X Syndrome:(show all 31)
Search GEO for disease gene expression data for Triple X Syndrome.
28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet