Aliases & Classifications for Trypanosomiasis

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Aliases & Descriptions for Trypanosomiasis:

Name: Trypanosomiasis 11 13 48 37 66

Classifications:



External Ids:

Disease Ontology11 DOID:10113
ICD1028 B57.2
ICD9CM30 086, 086.9
MeSH37 D014352

Summaries for Trypanosomiasis

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Disease Ontology:11 A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus trypanosoma in animals and humans.

MalaCards based summary: Trypanosomiasis is related to babesiosis and louping ill, and has symptoms including trypanosomal chancre An important gene associated with Trypanosomiasis is APOL1 (Apolipoprotein L1), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and IgA-Producing B Cells in the Intestine. The drugs pentamidine and pentamidine isethionate have been mentioned in the context of this disorder. Affiliated tissues include testes, heart and brain, and related mouse phenotypes are liver/biliary system and neoplasm.

Wikipedia:69 Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic... more...

Related Diseases for Trypanosomiasis

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Diseases related to Trypanosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 393)
idRelated DiseaseScoreTop Affiliating Genes
1babesiosis30.8IL10, IL1B, IL6, TNF
2louping ill30.0CCL2, CXCL8, IFNG, IL2, TNF
3malaria26.6ALB, CCL2, CCL3, CCL5, CXCL8, HP
4sleeping sickness12.0
5trypanosomiasis, human east-african12.0
6trypanosomiasis, human west-african11.9
7chagas disease11.9
8piepkorn karp hickok syndrome10.9IL10, TNF
9thyroid malformation10.9IL1B, TNF
10panner disease10.9IFNG, IL6, TNF
11ethmoid sinus adenoid cystic carcinoma10.8IL10, IL6, TNF
12hernia of ovary and fallopian tube10.8IFNG, IL10, TNF
13herpangina10.8IFNG, IL10, IL6
14sensorineural hearing loss10.8IFNG, IL10, TNF
15benign adult familial myoclonic epilepsy10.8CXCL8, IL10, IL6
16idiopathic neutropenia10.8IFNG, IL10, IL6
17baetz-greenwalt syndrome10.8IFNG, IL1B, TNF
18primary biliary cirrhosis10.8IL10, IL6, TNF
19antigen-peptide-transporter 2 deficiency10.8CCL2, IL6, TNF
20scrotum paget's disease10.8IL1B, IL6, TNF
21marchiafava bignami disease10.8CXCL8, IL10, IL6
22hypothyroidism10.8IL1B, IL6, TNF
23autoimmune polyendocrine syndrome10.8IL1B, IL6, TNF
24cytomegalovirus retinitis10.8CCL2, CXCL8
25opiate dependence10.8CCL2, IFNG, IL6
26scarlet fever10.8IL1B, IL6, TNF
27hypospadias, hypertelorism, upper lid coloboma, and mixed-type hearing loss10.8IL1B, TNF
28non-secretory myeloma10.8IL1B, IL6, TNF
29corneal deposit10.8CXCL8, IL1B, IL6
30tarsal tunnel syndrome10.8CXCL8, IL1B, IL6
31scrub typhus10.8ALB, TNF
32distal monosomy 9p10.8CXCL8, IFNG, IL10
33mechanical lagophthalmos10.8CXCL8, IL6, TNF
34pernicious anemia10.8IDO1, IL10, IL1B
35thoracic aortic aneurysm10.7IL1B, IL6, TNF
36paraphimosis10.7CXCL8, IL1B, TNF
37staphyloenterotoxemia10.7CXCL8, IL6, TNF
38gasserian ganglion meningioma10.7CCL2, CXCL8, IL6
39foodborne botulism10.7IL1B, IL6, TNF
40melioidosis10.7IFNG, IL10, IL6
41inflammatory spondylopathy10.7CXCL8, IL1B, IL6
42cat-scratch disease10.7IDO1, IL10, IL1B
43ocular cancer10.7CXCL8, IL1B, IL6
44keloids10.7IL1B, IL6, TNF
45myoclonus epilepsy10.7IFNG, IL4
46scrotum melanoma10.7CCL2, CXCL8, IL6
47mastocytosis cutaneous with short stature conductive hearing loss and microtia10.7IFNG, IL10, IL6, TNF
48hemophagocytic lymphohistiocytosis10.7IFNG, IL10, IL6, TNF
49leukostasis10.7IFNG, IL10, IL6, TNF
50cartilage disease10.7ALB, IL1B, TNF

Graphical network of the top 20 diseases related to Trypanosomiasis:



Diseases related to trypanosomiasis

Symptoms for Trypanosomiasis

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UMLS symptoms related to Trypanosomiasis:


trypanosomal chancre

Drugs & Therapeutics for Trypanosomiasis

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Drugs for Trypanosomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EnalaprilatPhase 411776420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
Enalaprilat
Enalaprilat (USP)
 
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline—water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalaprilat dihydrate
enalaprilat hydrate
enalprilat hydrate
enalprilate hydrate
2
protease inhibitorsPhase 45157
Synonyms:
 
protease inhibitors
3
EnalaprilPhase 411775847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
4
CarvedilolPhase 415772956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
5
EflornithinePhase 4, Phase 3, Phase 23570052-12-93009
Synonyms:
(RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid
.alpha.-DFMO HCl
2,5-diamino-2-(difluoromethyl)pentanoic acid
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrochloride
2-(Difluoromethyl)-DL-ornithine
2-(Difluoromethyl)-DL-ornithine HCl
2-(Difluoromethyl)-DL-ornithine hydrochloride
2-(Difluoromethyl)-DL-ornithine monohydrochloride
2-(Difluoromethyl)-DL-ornithine monohydrochloride, monohydrate
2-(Difluoromethyl)-DL-ornithine monohydrochloride.monohydrate
2-(Difluoromethyl)ornithine
2-(Difluoromethyl)ornithine hydrochloride hydrate
67037-37-0
68278-23-9
70050-56-5
70052-12-9
70052-12-9 (Parent)
96020-91-6
96020-91-6 (mono-hydrochloride, monohydrate)
AC-388
AC-5497
AC1L1EYW
AC1L1M41
AC1L9B1G
BMS 203522
BRN 2250529
C07997
C6H12F2N2O2.HCl.H2O
CCRIS 3295
CCRIS 3718
CCRIS 5805
CHEBI:41948
CHEMBL1201037
CHEMBL536971
CID3009
CID441361
CID57004
CPP-1X
D,L-alpha-Difluoromethylornithine
D,L-alpha-Difluoromethylornithine hydrochloride
D00829
D07883
D193_SIGMA
DFMO
DFMO (growth regulator)
DFMO HCl
DFMO hydrochloride
DFMO hydrochloride hydrate
DL-.alpha.-Difluoromethylornithine
DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride
DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
DL-alpha-(Difluoromethyl)ornithine
DL-alpha-Difluoromethylornithine
DL-alpha-Difluoromethylornithine hydrochloride
 
DL-alpha-Difluoromethylornithine hydrochloride hydrate
DL-alpha-Difluoromethylornithine, Hydrochloride
Difluoromethylornithine
Difluromethylornithine
EFLORNITHINE
EFLORNITHINE HYDROCHLORIDE
EINECS 269-532-0
EU-0100429
Eflornithine (INN)
Eflornithine HCl
Eflornithine [INN:BAN]
Eflornithine hydrochloride (USAN)
Eflornithine hydrochloride [USAN]
Eflornithine hydrochloride hydrate
Eflornithine hydrochloride monohydrate
Eflornithinum
Eflornithinum [Latin]
Eflornitina
Eflornitina [Spanish]
FT-0082608
FT-0082826
HSCI1_000267
I06-0316
I06-0530
LS-178282
LS-185084
LS-7332
LS-98405
Lopac0_000429
MDL 71,782 A
MDL 71782
MDL-71782A
MLS000069341
MLS001332583
MolPort-003-940-991
N-Difluoromethylornithine
NCGC00015316-03
NCGC00093850-01
NCGC00162152-01
NSC270295
NSC337250
Ornidyl
Ornidyl (TN)
Ornithine, 2-(difluoromethyl)-, monohydrochloride
RMI 71782
RMI-71782
SBB066102
SMR000058442
UNII-4NH22NDW9H
UNII-ZQN1G5V6SR
Vaniqa
alpha,delta-Diamino-alpha-(difluoromethyl)valeric acid
alpha-(Difluoromethyl)-DL-ornithine
alpha-Difluoromethylornithine
alpha-Difluoromethylornithine hydrochloride
dfmo
α-difluoromethylornithine
6
WarfarinPhase 444181-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
7
AspirinPhase 4107450-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
8
ornithineNutraceuticalPhase 4, Phase 3, Phase 26770-26-86262
Synonyms:
(+)-S-Ornithine
(S)-2,5-Diaminopentanoate
(S)-2,5-Diaminopentanoic acid
(S)-2,5-diaminovaleric acid
(S)-Ornithine
(S)-a,D-Diaminovalerate
 
(S)-a,D-Diaminovaleric acid
(S)-alpha,delta-Diaminovaleric acid
(S)-ornithine
(S)-α,δ-diaminovaleric acid
5-Amino-L-Norvaline
L-(-)-Ornithine
L-Ornithine
9
coumarinNutraceuticalPhase 41491-64-5323
Synonyms:
1, 2-Benzopyrone
2-Oxo-1,2-benzopyran
2-Oxo-2H-1-Benzopyran
2H-1-Benzopyran-2-one
2H-Benzo[b]pyran-2-one
2H-Chromen-2-one
2H-Chromen-2-one (ACD/Name 4.0)
5,6-Benzo-2-pyrone
Benzo-a-pyrone
Benzo-alpha-pyrone
 
Coumarin
Coumarine
Coumarinic anhydride
Cumarin
Kumarin
O-Hydroxycinnamic acid lactone
O-Hydroxycinnamic lactone
O-Hydroxyzimtsaure-lacton
Rattex
Tonka bean camphor
cis-O-Coumarinic acid lactone
{2H-Benzo[b]pyran-2-one}
10
BisoprololPhase 36166722-44-92405
Synonyms:
(+-)-1-((alpha-(2-Isopropoxyethoxy)-P-tolyl)oxy)-3-(isopropylamino)-2-propanol
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
66722-44-9
AB00514681
AC-18540
AC1L1DLQ
AKOS005110983
ARONIS24082
BISOPROLOL
BPBio1_000373
BSPBio_000339
Bisocor
Bisoprolol
Bisoprolol (USAN/INN)
Bisoprolol Fumarate
Bisoprolol Hemifumarate
Bisoprolol [USAN:BAN:INN]
Bisoprolol fumerate
Bisoprolol hemifumarate
Bisoprololum
Bisoprololum [Latin]
C06852
C18H31NO4
CHEBI:3127
CHEMBL645
CID2405
 
CL-297939
Cardicor
Concor
Condyline
Condylox
D02342
DB00612
Detensiel
EMD-33-512
EMD-33512
Emconcor
Emcor
Euradal
I01-7040
Isoten
L000133
LS-122509
MolPort-005-937-320
Monocor
NCGC00024868-02
NCGC00024868-03
NCGC00024868-04
NCGC00024868-05
Prestwick0_000330
Prestwick1_000330
Prestwick2_000330
Prestwick3_000330
SBB065120
SPBio_002260
Soloc
Soprol
UNII-Y41JS2NL6U
Zebeta
11
seleniumPhase 31717782-49-2
Synonyms:
Selanediide
Selenide
 
Selenide(2-)
Selenium
Selenium ion (Se2+)
12
PosaconazolePhase 252171228-49-2147912
Synonyms:
1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one
171228-49-2
177571-33-4
4-(p-(4-(p-(((3R,5R)-5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl)methoxy)phenyl)-1-piperazinyl)phenyl)-1-((1S,2S)-1-ethyl-2-hydroxypropyl)-delta(sup 2)-1,2,4-triazolin-5-one
4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
AC-1350
AC1L3W34
AC1LAHLQ
AKOS005145917
CHEBI:434337
CHEMBL1397
CHEMBL371938
CHEMBL371939
CID10532764
CID11520437
CID11542142
CID147912
CID468595
D02555
 
DB01263
HSDB 7421
LS-186118
LS-186988
LS-187630
MolPort-006-666-426
Noxafil
Noxafil (TN)
Noxafil, Posaconazole
Posaconazole
Posaconazole (USAN/INN)
Posaconazole SP
Posaconazole [USAN:INN:BAN]
Posaconazole in combination with MGCD290
S1257_Selleck
SCH-56592
SCH56592
Sch 56592
Spriafil
UNII-6TK1G07BHZ
X2N
posaconazole
13
PentamidinePhase 239100-33-44735
Synonyms:
1,3-BIS(4-AMIDINOPHENOXY)PENTANE
1,3-Bis(4-amidinophenoxy)pentane
1,5-Bis(4-amidinophenoxy)pentane
100-33-4
4, 4'-Diamidinodiphenoxypentane
4,4'-(1,5-Pentanediylbis(oxy))bis-benzenecarboximidamide
4,4'-(Pentamethylenedioxy)dibenzamide
4,4'-(Pentamethylenedioxy)dibenzamidine
4,4'-Diamidino-.alpha.,.omega.-diphenoxypentane
4,4'-Diamidinodiphenoxypentane
4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
4-10-00-00447 (Beilstein Handbook Reference)
4-[5-(4-Carbamimidoylphenoxy)pentoxy]benzenecarboximidamide
6823-79-6
AB00053572
AC-12459
AC1L1IU8
AC1Q4YYD
BPBio1_000689
BRN 3159790
BSPBio_000625
BSPBio_001752
Benzenecarboximidamide, 4,4'-(1,5-pentanediylbis(oxy))bis- (9CI)
C07420
C19H24N4O2
CCRIS 3825
CHEBI:45081
CHEMBL55
CID4735
D08333
DB00738
EINECS 202-841-0
HMS2089J14
HSDB 7474
KBio3_001252
KBioGR_000879
LS-27566
Lomidine
Lomidine (TN)
MB 800
MB-800
MolPort-001-792-506
NCGC00179034-01
NCGC00179034-02
NCI60_042221
NSC 9921
 
NSC620107
NSC9921
Nebupent
Nebupent (*Isethionate)
Nebupent (as isethionate)
P,P'-(pentamethylenedioxy)dibenzamidine
PENTAM
PENTAMIDINE ISETHIONATE
PNT
Pentacarinat
Pentacarinat (*Isethionate)
Pentacarinat (as isethionate)
Pentam 300
Pentam 300 (*Isethionate)
Pentam 300 (as isethionate)
Pentamide
Pentamidin
Pentamidina
Pentamidina [DCIT]
Pentamidindiisetionat
Pentamidine
Pentamidine (INN)
Pentamidine Isethionate
Pentamidine Isethionate 2-Hydroxy-Ethanesulfonic Acid
Pentamidine [INN:BAN:DCF]
Pentamidine isetionate
Pentamidine mesylate
Pentamidinum
Pentamidinum [INN-Latin]
Pneumopent
Prestwick1_000553
Prestwick2_000553
Prestwick3_000553
RP 2512 (*Isethionate)
RP-2512
SPBio_000290
SPBio_002546
Spectrum2_000155
Spectrum3_000276
Spectrum4_000380
Spectrum5_001808
UNII-673LC5J4LQ
WLN: MUYZR DO5OR DYZUM
nchembio873-comp32
p,p'-(Pentamethylene-dioxy)bis-benzamidine
p,p'-(Pentamethylenedioxy)bis[benzamidine]
p,p'-(Pentamethylenedioxy)dibenzamidine
pentamidine
14
Maleic acidPhase 2292110-16-7444266
Synonyms:
(2Z)-2-Butenedioate
(2Z)-2-Butenedioic acid
(2Z)-Butene-2-dioate
(2Z)-Butene-2-dioic acid
(2Z)-but-2-enedioate
(2Z)-but-2-enedioic acid
(Z)-2-Butenedioate
(Z)-2-Butenedioic acid
(z)-butenedioate
(z)-butenedioic acid
2-Butenedioate
2-Butenedioic acid
Cis-butenedioate
Cis-butenedioic acid
 
H2male
Kyselina maleinova
MAE
Maleate
Maleic acid
Maleic acid [NA2215]
Maleinic acid
Malenic acid
Malezid CM
Scotchbond multipurpose etchant
Toxilic acid
cis-1,2-Ethylenedicarboxylic acid
cis-2-Butenedioate
cis-2-Butenedioic acid
cis-But-2-enedioate
cis-But-2-enedioic acid
15
MiconazolePhase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
16lenograstimPhase 21178
17
amiodarone1181951-25-32157
Synonyms:
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone
(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone
(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
1951-25-3
2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran
2-Butyl-3-[3,5-diiodo-4-(2-di
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
2-N-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
5-18-02-00353 (Beilstein Handbook Reference)
AB00053422
AC1L1D1R
AC1Q2VCU
ASTA Medica Brand of Amiodarone Hydrochloride
Alphapharm Brand of Amiodarone Hydrochloride
Amidorone
Aminodarone
Amio-Aqueous IV
Amiobeta
Amiodarex
Amiodarona
Amiodarona [INN-Spanish]
Amiodarone
Amiodarone (USAN/INN)
Amiodarone Base
Amiodarone HCL
Amiodarone Hydrochloride
Amiodarone [USAN:BAN:INN]
Amiodarons
Amiodaronum
Amiodaronum [INN-Latin]
Amiohexal
Amjodaronum
Ancar
Aratac
Armstrong Brand of Amiodarone Hydrochloride
Arycor
BIDD:GT0425
BIDD:PXR0146
BPBio1_000372
BRN 1271711
BSPBio_000338
BSPBio_001574
BSPBio_002580
Berenguer Infale Brand of Amiodarone Hydrochloride
Betapharm Brand of Amiodarone Hydrochloride
Bio1_000026
Bio1_000515
Bio1_001004
Bio2_000294
Bio2_000774
Braxan
C06823
C25H29I2NO3
CAS-19774-82-4
CBiol_001740
CHEBI:2663
CHEMBL633
CID2157
Corbionax
Cordarex
Cordarone
Cordarone Intravenous
D000638
D02910
DB01118
DivK1c_000079
EINECS 217-772-1
 
G Gam Brand of Amiodarone Hydrochloride
HMS1791O16
HMS1989O16
HMS2089C07
Hexal Brand of Amiodarone Hydrochloride
IDI1_000079
IDI1_034044
KBio1_000079
KBio2_000294
KBio2_000741
KBio2_002862
KBio2_003309
KBio2_005430
KBio2_005877
KBio3_000587
KBio3_000588
KBio3_001800
KBioGR_000294
KBioGR_001859
KBioSS_000294
KBioSS_000741
Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl (7CI,8CI)
Kordaron
L 3428
L-3428
L001174
L3428
LS-87088
Labaz
Leurquin Brand of Amiodarone Hydrochloride
Lopac-A-8423
Lopac0_000122
MolPort-003-703-670
NCGC00015096-01
NCGC00015096-02
NCGC00015096-03
NCGC00015096-10
NCGC00024242-03
NCGC00024242-04
NCGC00024242-05
NCGC00024242-06
NCI60_041885
NINDS_000079
Ortacrone
Pacerone
Pharma Investi Brand of Amiodarone Hydrochloride
Prestwick0_000409
Prestwick1_000409
Prestwick2_000409
Prestwick3_000409
QTL1_000008
Rytmarone
SKF 33134-A
SKF 33134A
SPBio_001825
SPBio_002277
STK529812
STOCK1S-12240
Sanofi Winthrop Brand of Amiodarone Hydrochloride
Sedacoron
Sedacorone
Spectrum2_001813
Spectrum3_001050
Spectrum4_001190
Spectrum5_001533
Spectrum_000261
Tachydaron
UNII-N3RQ532IUT
UNM000001215003
Wyeth Brand of Amiodarone Hydrochloride
amiodarone
ethylaminoethoxy)benzoyl]benzofuran
nchembio.79-comp9
nchembio732-comp1
on
pms-Amiodarone

Interventional clinical trials:

(show top 50)    (show all 64)
idNameStatusNCT IDPhase
1Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic PhaseCompletedNCT00906880Phase 4
2Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas DiseaseCompletedNCT01755403Phase 4
3A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
4Outcomes of an Anticoagulation Clinic in an University HospitalCompletedNCT01006486Phase 4
5Exercise Training in Chagas CardiomyopathyCompletedNCT01006473Phase 4
6Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)RecruitingNCT01650792Phase 4
7Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas DiseaseRecruitingNCT01539161Phase 4
8Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas DiseaseActive, not recruitingNCT01678599Phase 4
9Population Pharmacokinetics Study of Benznidazole in Children With Chagas'DiseaseActive, not recruitingNCT01549236Phase 4
10Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African TrypanosomiasisCompletedNCT00146627Phase 3
11Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRCCompletedNCT01589289Phase 3
12Cardiac Rehabilitation in Chagas Heart FailureCompletedNCT02516293Phase 2, Phase 3
13Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Clinical TrialCompletedNCT02386358Phase 3
14Chagas Cardiomyopathy Bisoprolol Intervention Study: CharityCompletedNCT00323973Phase 3
15Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2RecruitingNCT01685827Phase 2, Phase 3
16Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal StudyRecruitingNCT02169557Phase 2, Phase 3
17BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' DiseaseRecruitingNCT00123916Phase 3
18Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal StudyRecruitingNCT02184689Phase 2, Phase 3
19CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)RecruitingNCT02369978Phase 2, Phase 3
20Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' DiseaseRecruitingNCT02625974Phase 3
21Selenium Treatment and Chagasic Cardiopathy (STCC)RecruitingNCT00875173Phase 3
22Physical Exercise Program in Chronic Chagas Heart DiseaseActive, not recruitingNCT02517632Phase 3
23Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, UgandaTerminatedNCT00489658Phase 2, Phase 3
24Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African TrypanosomiasisTerminatedNCT00330148Phase 3
25Cell Therapy in Chagas CardiomyopathyTerminatedNCT00349271Phase 3
26A Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00802594Phase 2
27Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00803933Phase 2
28A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)CompletedNCT01377480Phase 2
29Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And BenznidazoleCompletedNCT01162967Phase 2
30Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas DiseaseRecruitingNCT02498782Phase 2
31Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas DiseaseRecruitingNCT01489228Phase 2
32Evaluation of G-CSF (Colony Stimulating Factor) in Patients With Chronic Chagas CardiomyopathyEnrolling by invitationNCT02154269Phase 2
33Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158CompletedNCT01533961Phase 1
34Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the FexinidazoleCompletedNCT00982904Phase 1
35Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market FormulationCompletedNCT02571062Phase 1
36Fexinidazole (1200mg) Bioavailability Under Different Food Intake ConditionsCompletedNCT01340157Phase 1
37Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT02606864Phase 1
38Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT01927224Phase 1
39Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With FoodTerminatedNCT01483170Phase 1
40Abbott ESA Chagas Assay Post-Market StudyCompletedNCT01662362
41Longitudinal Study of Patients With Chronic Chagas Cardiomyopathy in Brazil (SaMi_Trop Project)CompletedNCT02646943
42Determination of Genetic Polymorphisms in Chronic Chagas CardiomyopathyCompletedNCT02346123
43Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas DiseaseCompletedNCT02327052
44Effect of Ganglionar Electrical Stimulation on Central Arterial PressureCompletedNCT01874795
45Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas CardiomyopathyCompletedNCT01863576Phase 0
46MicroRNAs as Biomarkers in Patients With Chagas DiseaseCompletedNCT01842880
47Syndecan-4 as a Biomarker in Patients With Chagas DiseaseCompletedNCT01842867
48Galectin-3 as a Biomarker in Patients With Chagas DiseaseCompletedNCT01842854
49Congenital Transmission of Lineages I and II of Trypanosoma CruziCompletedNCT01787968
50New Tools for the Diagnosis, Prognosis and Treatment Follow-up in Chagas DiseaseCompletedNCT01755377

Search NIH Clinical Center for Trypanosomiasis

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: trypanosomiasis

Genetic Tests for Trypanosomiasis

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Anatomical Context for Trypanosomiasis

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MalaCards organs/tissues related to Trypanosomiasis:

34
Testes, Heart, Brain, T cells, B cells, Endothelial, Myeloid

Animal Models for Trypanosomiasis or affiliated genes

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MGI Mouse Phenotypes related to Trypanosomiasis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.0ALB, HP, IFNG, IL10, IL2, IL4
2MP:00020068.6ALB, HP, IFNG, IL10, IL1B, IL2
3MP:00053878.0CCL2, CCL5, HP, IDO1, IFNG, IL10
4MP:00053847.9ALB, CALR, HP, IDO1, IFNG, IL10
5MP:00053977.6CCL5, HP, IDO1, IFNG, IL10, IL1B
6MP:00053767.4ALB, CALR, HP, IDO1, IFNG, IL10

Publications for Trypanosomiasis

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Articles related to Trypanosomiasis:

(show top 50)    (show all 605)
idTitleAuthorsYear
1
Human Leukocyte Antigen-G: A Promising Prognostic Marker of Disease Progression to Improve the Control of Human African Trypanosomiasis. (27470243)
2016
2
Recent Updates on Development of Drug Molecules for Human African Trypanosomiasis. (27072715)
2016
3
West African Trypanosomiasis with Central Nervous System Involvement. (27582522)
2016
4
Trypanosomiasis-induced megacolon illustrates how myenteric neurons modulate the risk for colon cancer in rats and humans. (25884710)
2015
5
Human African trypanosomiasis in non-endemic countries. (25650203)
2015
6
Oral Multicomponent DNA Vaccine Delivered by Attenuated Salmonella Elicited Immunoprotection Against American Trypanosomiasis. (25160983)
2014
7
Social factors affecting seasonal variation in bovine trypanosomiasis on the Jos Plateau, Nigeria. (24172046)
2013
8
HLA-G 3' UTR-2 haplotype is associated with Human African trypanosomiasis susceptibility. (23541412)
2013
9
Modeling the control of trypanosomiasis using trypanocides or insecticide-treated livestock. (22616017)
2012
10
Human African trypanosomiasis in South Sudan: how can we prevent a new epidemic? (22666506)
2012
11
A review of QSAR studies to discover new drug-like compounds actives against leishmaniasis and trypanosomiasis. (22352913)
2012
12
Trypanosomiasis in an infant from India. (21715739)
2011
13
Transmission of human African trypanosomiasis in the Komo-Mondah focus, Gabon. (22121444)
2011
14
African trypanosomiasis. (21609334)
2011
15
Tsetse fly control and trypanosomiasis in Africa, quo vadis? (21104211)
2011
16
Identification of Selective Inhibitors of Phosphofructokinase as Lead Compounds Against Trypanosomiasis (24027803)
2010
17
Novel biomarkers for late-stage human African trypanosomiasis--the search goes on. (20519588)
2010
18
Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation. (20605052)
2010
19
Atypical human trypanosomiasis: a neglected disease or just an unlucky accident? (19162551)
2009
20
Justice where justice is due: A posthumous Nobel Prize to Carlos Chagas (1879-1934), the discoverer of American Trypanosomiasis (Chagas' disease). (19185367)
2009
21
Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis. (19828449)
2009
22
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. (19289530)
2009
23
Regulatory T cells prevent control of experimental African trypanosomiasis. (18250461)
2008
24
Contributions of experimental mouse models to the understanding of African trypanosomiasis. (18684669)
2008
25
American trypanosomiasis in dogs from an urban and rural area of Yucatan, Mexico. (18597661)
2008
26
Novel markers for treatment outcome in late-stage Trypanosoma brucei gambiense trypanosomiasis. (18494605)
2008
27
Hypocretin and human African trypanosomiasis. (18363311)
2008
28
Knowledge, behaviours, practices and beliefs regarding Human African Trypanosomiasis (HAT) among inhabitants of Kinshasa (Democratic Republic of Congo). (19359235)
2008
29
Sleeping glands? - The role of endocrine disorders in sleeping sickness (T.b. gambiense Human African Trypanosomiasis). (17767911)
2007
30
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system. (16965857)
2007
31
A systematic strategy for large-scale analysis of genotype phenotype correlations: identification of candidate genes involved in African trypanosomiasis. (17709344)
2007
32
Development and evaluation of new diagnostic tests for human African trypanosomiasis. (16671230)
2006
33
Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor. (16604085)
2006
34
Immunology and immunopathology of African trypanosomiasis. (17143404)
2006
35
Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis. (16080099)
2005
36
Disruptions of ultradian and circadian organization of core temperature in a rat model of African trypanosomiasis using periodogram techniques on detrended data. (16021841)
2005
37
Congenital trypanosomiasis. (15537729)
2004
38
American trypanosomiasis in central Mexico: Trypanosoma cruzi infection in triatomine bugs and mammals from the municipality of Jiutepec in the state of Morelos. (15257803)
2004
39
Antibodies directed against nitrosylated neoepitopes in sera of patients with human African trypanosomiasis. (15482403)
2004
40
A bloodstream Trypanosoma congolense sialidase could be involved in anemia during experimental trypanosomiasis. (12869528)
2003
41
American trypanosomiasis (Chagas' disease) and the role of molecular epidemiology in guiding control strategies. (12829559)
2003
42
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. (12743807)
2003
43
Current chemotherapy of human African trypanosomiasis. (12811544)
2003
44
Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis. (11348533)
2001
45
Are there new approaches to roll back trypanosomiasis? (11348526)
2001
46
An evaluation of the reactivity of the card agglutination test for trypanosomiasis (CATT) reagent in the Fontem sleeping sickness focus, Cameroon. (7839945)
1994
47
Human African trypanosomiasis (T.b. gambiense): a study of 16 fatal cases of sleeping sickness with some observations on acute reactive arsenical encephalopathy. (3703156)
1986
48
Field evaluation of Cellognost indirect haemagglutination test in the diagnosis of human trypanosomiasis (sleeping sickness) in Kura local government area of Kano State, Nigeria. (2862781)
1985
49
The public health significance of trypanosomiasis (sleeping sickness) in Nigeria. (4055267)
1985
50
Immunosuppression in experimental trypanosomiasis: effects of Trypanosoma brucei on immunization against louping-ill virus and lymphocytic choriomeningitis virus. (232108)
1979

Variations for Trypanosomiasis

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Expression for genes affiliated with Trypanosomiasis

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Search GEO for disease gene expression data for Trypanosomiasis.

Pathways for genes affiliated with Trypanosomiasis

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Pathways related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL1B, IL4, IL6
29.7IL10, IL4, IL6, TNF
39.6IFNG, IL10, IL2, IL6
49.6IL10, IL1B, IL6, TNF
59.6CCL2, IFNG, IL1B, TNF
69.5IFNG, IL10, IL2, IL4
79.5IFNG, IL10, IL2, IL4
89.5CXCL8, IL1B, IL6, TNF
99.4IFNG, IL10, IL1B, IL6, TNF
109.4CXCL8, IFNG, IL2, IL6, TNF
119.4CXCL8, IL10, IL1B, IL6, TNF
12
Show member pathways
9.4CXCL8, IFNG, IL1B, IL6, TNF
139.3CCL2, CXCL8, IL1B, IL6, TNF
14
Show member pathways
9.3CXCL8, IFNG, IL2, IL4, TNF
159.3CXCL8, IFNG, IL2, IL4, IL6
169.2CCL2, CCL3, IL1B, TNF
179.2CALR, IFNG, IL1B, IL6, TNF
189.2CXCL8, IFNG, IL10, IL1B, IL6, TNF
199.2IFNG, IL10, IL2, IL4, IL6, TNF
209.1CCL2, CCL5, IL1B, IL6, TNF
21
Show member pathways
9.1CXCL8, IFNG, IL1B, IL4, IL6, TNF
22
Show member pathways
9.1CCL3, IFNG, IL10, IL2, TNF
23
Show member pathways
9.1ALB, CCL2, IFNG, IL1B, IL6, TNF
24
Show member pathways
9.1IFNG, IL10, IL1B, IL2, IL6, TNF
259.1IFNG, IL10, IL1B, IL2, IL6, TNF
269.1CXCL8, IL10, IL1B, IL6, TF, TNF
27
Show member pathways
9.0CCL3, CXCL8, IFNG, IL1B, IL6
289.0CCL3, CXCL8, IFNG, IL1B, IL6
299.0CCL2, CXCL8, IFNG, IL10, IL1B, IL6
30
Show member pathways
8.9ALB, APOL1, CALR, HP, HPR
31
Show member pathways
8.9CCL2, CCL5, CXCL8, IL1B, IL6, TNF
32
Show member pathways
8.9CCL2, IFNG, IL10, IL1B, IL2, IL6
33
Show member pathways
8.8CCL3, IFNG, IL1B, IL2, IL4
348.8IFNG, IL10, IL1B, IL2, IL4, IL6
35
Show member pathways
8.8IFNG, IL10, IL1B, IL2, IL4, IL6
36
Show member pathways
8.6CXCL8, IFNG, IL10, IL1B, IL2, IL4
378.6CCL2, CXCL8, IFNG, IL1B, IL2, IL4
388.6APOL1, HPR, IDO1, IFNG, IL10, IL1B
398.5CCL3, IFNG, IL10, IL1B, IL2, IL4
40
Show member pathways
8.4CALR, IFNG, IL10, IL1B, IL2, IL4
418.2CCL2, CCL3, CCL5, CXCL8, IFNG, IL1B
428.2CCL2, CCL5, IDO1, IFNG, IL10, IL1B
43
Show member pathways
8.2CCL2, CCL5, CXCL8, IFNG, IL1B, IL2
44
Show member pathways
7.7CCL2, CCL3, CCL5, CXCL8, IL10, IL1B
45
Show member pathways
7.7CCL2, CCL3, CCL5, CXCL8, IL10, IL1B
467.7CCL2, CCL3, CCL5, CXCL8, IL10, IL1B
47
Show member pathways
7.6CCL2, CCL3, CCL5, CXCL8, IFNG, IL10
48
Show member pathways
7.5CCL2, CCL3, CCL5, CXCL8, IFNG, IL10
49
Show member pathways
7.5CCL2, CCL3, CCL5, CXCL8, IFNG, IL10
50
Show member pathways
7.3CALR, CCL2, CCL3, CCL5, CXCL8, IFNG

GO Terms for genes affiliated with Trypanosomiasis

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Cellular components related to Trypanosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.6CALR, IFNG, IL4, IL6, TNF
2blood microparticleGO:00725629.1ALB, APOL1, HP, HPR, TF
3extracellular spaceGO:00056156.1ALB, APOL1, CALR, CCL2, CCL3, CCL5
4extracellular regionGO:00055765.7ALB, APOL1, CALR, CCL2, CCL3, CCL5

Biological processes related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idNameGO IDScoreTop Affiliating Genes
1neutrophil apoptotic processGO:000178110.9IFNG, IL6
2receptor biosynthetic processGO:003280010.8IL10, TNF
3positive regulation of vitamin D biosynthetic processGO:006055710.8IFNG, TNF
4chronic inflammatory response to antigenic stimulusGO:000243910.7IL1B, TNF
5cellular response to high density lipoprotein particle stimulusGO:007140310.5CCL2, CCL5
6negative regulation of growth of symbiont in hostGO:004413010.5IFNG, IL10, TNF
7positive regulation of MHC class II biosynthetic processGO:004534810.5IFNG, IL10, IL4
8positive regulation of calcidiol 1-monooxygenase activityGO:006055910.5IFNG, IL1B, TNF
9positive regulation of membrane protein ectodomain proteolysisGO:005104410.5IFNG, IL1B, TNF
10humoral immune responseGO:000695910.4CCL2, IFNG, IL6, TNF
11positive regulation of isotype switching to IgG isotypesGO:004830410.4IFNG, IL2, IL4
12defense response to protozoanGO:004283210.3IFNG, IL10, IL4, IL6
13positive regulation of osteoclast differentiationGO:004567210.3CCL5, IFNG, TNF
14positive regulation of chemokine biosynthetic processGO:004508010.2IFNG, IL1B, IL4, TNF
15positive regulation of JAK-STAT cascadeGO:004642710.2CCL5, IL10, IL6
16positive regulation of fever generationGO:003162210.2CCL5, IL1B, TNF
17cellular response to fibroblast growth factor stimulusGO:004434410.1CCL2, CCL5, CXCL8
18positive regulation of cell adhesionGO:004578510.0CCL2, CCL5, IFNG, TNF
19regulation of insulin secretionGO:005079610.0CCL5, IFNG, IL1B, TNF
20lymphocyte chemotaxisGO:00482479.9CCL2, CCL3, CCL5
21positive regulation of nitric oxide biosynthetic processGO:00454299.9IFNG, IL1B, IL6, TNF
22positive regulation of phagocytosisGO:00507669.9CALR, IL1B, TNF
23macrophage chemotaxisGO:00482469.9CCL2, CCL3, CCL5
24response to glucocorticoidGO:00513849.9CCL2, CCL5, IL10, IL6, TNF
25response to organic substanceGO:00100339.9ALB, CALR, IL10, TNF
26response to virusGO:00096159.9CCL5, IFNG, ODC1, TNF
27cellular response to lipopolysaccharideGO:00712229.8CCL2, CXCL8, IFNG, IL10, IL6, TNF
28positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.8IL10, IL1B, IL4, IL6, TNF
29monocyte chemotaxisGO:00025489.7CCL2, CCL3, CCL5, IL6
30response to lipopolysaccharideGO:00324969.7CCL2, IDO1, IL10, IL1B, IL6
31positive regulation of inflammatory responseGO:00507299.6CCL2, CCL3, CCL5, IL2
32chemokine-mediated signaling pathwayGO:00700989.6CCL2, CCL3, CCL5, CXCL8
33lipopolysaccharide-mediated signaling pathwayGO:00316639.5CCL2, CCL3, CCL5, IL1B, TNF
34agingGO:00075689.5CCL2, CCL5, IL10, IL1B, IL6
35protein kinase B signalingGO:00434919.5CCL2, CCL3, CCL5, IL1B, TNF
36cellular response to interleukin-1GO:00713479.5CCL2, CCL3, CCL5, CXCL8, IL6
37cellular response to tumor necrosis factorGO:00713569.4CCL2, CCL3, CCL5, CXCL8, IL6
38cellular response to organic cyclic compoundGO:00714079.3CCL2, CCL3, CCL5, IL1B, TNF
39receptor-mediated endocytosisGO:00068989.3ALB, APOL1, CALR, HP, HPR
40chemotaxisGO:00069359.3CCL2, CCL3, CCL5, CXCL8, IL4
41cell-cell signalingGO:00072679.1CCL3, CCL5, IL10, IL1B, IL2
42neutrophil chemotaxisGO:00305939.1CCL2, CCL3, CCL5, CXCL8, IFNG, IL1B
43positive regulation of T cell proliferationGO:00421029.1CCL5, IFNG, IL1B, IL2, IL4, IL6
44cellular calcium ion homeostasisGO:00068749.0CALR, CCL2, CCL3, CCL5
45positive regulation of gene expressionGO:00106288.9CALR, CCL3, IFNG, IL1B, IL6, TNF
46MAPK cascadeGO:00001658.9CCL2, CCL3, CCL5, IL1B, IL2, TNF
47positive regulation of cell proliferationGO:00082848.8CALR, IFNG, IL2, IL4, IL6, ODC1
48positive regulation of ERK1 and ERK2 cascadeGO:00703748.7CCL2, CCL3, CCL5, IL1B, IL6, TNF
49response to drugGO:00424938.7CALR, CCL2, CCL5, IFNG, IL10, IL4
50inflammatory responseGO:00069548.5CCL2, CCL3, CCL5, CXCL8, IDO1, IL10

Molecular functions related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1hemoglobin bindingGO:003049210.4HP, HPR
2phospholipase activator activityGO:001600410.0CCL3, CCL5
3CCR1 chemokine receptor bindingGO:003172610.0CCL3, CCL5
4CCR5 chemokine receptor bindingGO:00317309.9CCL3, CCL5
5growth factor activityGO:00080839.5IL10, IL2, IL4, IL6
6chemokine activityGO:00080099.1CCL2, CCL3, CCL5, CXCL8
7cytokine activityGO:00051258.3CCL2, IFNG, IL10, IL1B, IL2, IL4

Sources for Trypanosomiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet