MCID: TRY001
MIFTS: 51

Trypanosomiasis malady

Category: Infectious diseases

Aliases & Classifications for Trypanosomiasis

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Aliases & Descriptions for Trypanosomiasis:

Name: Trypanosomiasis 11 50 39 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:10113
ICD1030 B57.2
ICD9CM32 086, 086.9
MeSH39 D014352

Summaries for Trypanosomiasis

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Disease Ontology:11 A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.

MalaCards based summary: Trypanosomiasis is related to loiasis and tuberculosis. An important gene associated with Trypanosomiasis is APOL1 (Apolipoprotein L1), and among its related pathways are Overview of nanoparticle effects and ATF-2 transcription factor network. The drugs pentamidine isethionate and pentamidine have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and heart, and related mouse phenotypes are liver/biliary system and cellular.

Wikipedia:71 Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic... more...

Related Diseases for Trypanosomiasis

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Diseases related to Trypanosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 362)
idRelated DiseaseScoreTop Affiliating Genes
1loiasis29.8IFNG, IL10, IL4
2tuberculosis29.6CCL2, IL10, IL1B, IL2, IL4, IL6
3sleeping sickness12.1
4chagas disease11.9
5trypanosomiasis, human east-african11.8
6trypanosomiasis, human west-african11.8
7intussusception10.4IL1B, TNF
8pyridoxal 5'-phosphate-dependent epilepsy10.4IL10, TNF
9transient tic disorder10.4IL10, IL6, TNF
10stocco dos santos syndrome10.4IFNG, IL1B, TNF
11tarsal tunnel syndrome10.4IDO1, IL10, TNF
12lepromatous leprosy10.4IFNG, IL10, IL6
13chronic apical periodontitis10.4IDO1, IL10, TNF
14multiple mitochondrial dysfunctions syndrome10.4IFNG, IL10, IL6
15neonatal hypoxic and ischemic brain injury10.4CXCL8, IL10, IL6
16anal paget's disease10.4IL1B, IL6, TNF
17bipolar i disorder10.4IL1B, IL6, TNF
18primary ciliary dyskinesia10.3IL10, IL6, TNF
19human immunodeficiency virus infectious disease10.3IL1B, IL6, TNF
20measles10.3IL1B, IL6, TNF
21oculomotor nerve paralysis10.3CXCL8, IL1B, IL6
22dextrocardia10.3IL1B, IL6, TNF
23common peroneal nerve lesion10.3CXCL8, IL1B, IL6
24congenital dyserythropoietic anemia10.3ALB, TNF
25megaloblastic anemia10.3IDO1, IL10, IL1B
26benign neonatal seizures10.3IL1B, IL6, TNF
27urea cycle disorder10.3IL10, IL1B, IL6
28schwannoma of ureter10.3CCL2, CXCL8, IL6
29cicatricial lagophthalmos10.3CXCL8, IL6, TNF
30usher syndrome, type 2a10.3IFNG, IL10, IL6
31immunodeficiency due to a late component of complement deficiency10.3CXCL8, IFNG, IL10
32bullous retinoschisis10.3CXCL8, IL1B, IL6
33carbuncle10.3CXCL8, IL1B, IL6
34keratoconus10.3IL1B, IL6, TNF
35splenic artery aneurysm10.3IL1B, IL6, TNF
36conduct disorder10.3IFNG, IL10, IL6, TNF
37pancreatic signet ring cell adenocarcinoma10.3IFNG, IL10, IL6, TNF
38myoglobinuria recurrent10.3IFNG, IL4
39orthostatic proteinuria10.3CXCL8, IL6, TNF
40disease of mental health10.3IFNG, IL10, IL6, TNF
41follicular adenoma10.3IFNG, IL10, IL6, TNF
42lateral cystocele10.3CCL2, CXCL8, IL6
43ciliary discoordination, due to random ciliary orientation10.3ALB, IFNG, IL10
44phlyctenulosis10.3IDO1, IL10, IL6, TNF
45rickettsialpox10.3IFNG, IL10, IL1B, TNF
46tubular renal disease-cardiomyopathy syndrome10.3IL10, IL4, TNF
47hypoparathyroidism-retardation-dysmorphism syndrome10.3IL10, IL1B, IL6, TNF
48rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies10.3IL10, IL1B, IL6, TNF
49asymptomatic neurosyphilis10.3IFNG, IL10, IL4
50pancreas lymphoma10.3IL1B, IL6, TNF

Graphical network of the top 20 diseases related to Trypanosomiasis:



Diseases related to trypanosomiasis

Symptoms & Phenotypes for Trypanosomiasis

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MGI Mouse Phenotypes related to Trypanosomiasis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.3ALB, HP, IFNG, IL10, IL2, IL4
2MP:00053848.7ALB, CALR, HP, IDO1, IFNG, IL10
3MP:00053878.7CCL2, CCL5, HP, IDO1, IFNG, IL10
4MP:00020068.6ALB, HP, IFNG, IL10, IL1B, IL2
5MP:00053978.6CCL5, HP, IDO1, IFNG, IL10, IL1B

Drugs & Therapeutics for Trypanosomiasis

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Drugs for Trypanosomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 72)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EnalaprilatapprovedPhase 412476420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
Enalaprilat
Enalaprilat (USP)
 
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline—water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalaprilat dihydrate
enalaprilat hydrate
enalprilat hydrate
enalprilate hydrate
2
WarfarinapprovedPhase 447081-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
3
Enalaprilapproved, vet_approvedPhase 412475847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
4
Carvedilolapproved, investigationalPhase 416872956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
5
Aspirinapproved, vet_approvedPhase 4115250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalicylsäure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide acetylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
Entericin
Enterophen
 
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
acide 2-(acétyloxy)benzoïque
acide acétylsalicylique
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
salicylic acid acetate
ácido acetilsalicílico
6Immunosuppressive AgentsPhase 4, Phase 3, Phase 213086
7Antiparasitic AgentsPhase 4, Phase 3, Phase 2, Phase 12199
8BenzonidazolePhase 4, Phase 3, Phase 212
9Antiprotozoal AgentsPhase 4, Phase 3, Phase 2, Phase 12051
10Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 122062
11
protease inhibitorsPhase 45471
Synonyms:
 
protease inhibitors
12Neurotransmitter AgentsPhase 4, Phase 318340
13Vasodilator AgentsPhase 43543
14Peripheral Nervous System AgentsPhase 4, Phase 323689
15NifurtimoxPhase 4, Phase 3, Phase 2, Phase 112
16Adrenergic alpha-AntagonistsPhase 4739
17AnticoagulantsPhase 42623
18Natriuretic Peptide, BrainPhase 4182
19HIV Protease InhibitorsPhase 45470
20Adrenergic beta-AntagonistsPhase 4, Phase 31193
21Adrenergic AntagonistsPhase 4, Phase 31573
22Antihypertensive AgentsPhase 4, Phase 34207
23Angiotensin-Converting Enzyme InhibitorsPhase 4724
24Adrenergic AgentsPhase 4, Phase 35352
25Adrenergic alpha-1 Receptor AntagonistsPhase 4480
26Antirheumatic AgentsPhase 410956
27Fibrinolytic AgentsPhase 42388
28AntipyreticsPhase 41605
29Cyclooxygenase InhibitorsPhase 42870
30Platelet Aggregation InhibitorsPhase 42516
31Anti-Inflammatory Agents, Non-SteroidalPhase 44443
32AnalgesicsPhase 411733
33Analgesics, Non-NarcoticPhase 46501
34Anti-Inflammatory AgentsPhase 410729
35
OrnithineNutraceuticalPhase 4, Phase 3, Phase 2713184-13-26262, 389
Synonyms:
(+)-S-Ornithine
(+/-)-2,5-Diaminopentanoic acid monohydrochloride
(S)-2,5-Diaminopentanoate
(S)-2,5-Diaminopentanoic acid
(S)-Ornithine
(S)-a,D-Diaminovalerate
(S)-a,D-Diaminovaleric acid
2,5-Diaminopentanoic acid hydrochloride
5-Amino-L-Norvaline
D -2,5-Diaminopentanoic acid
D-Ornithine
DL -2,5-Diaminopentanoic acid
DL-ornithine
DL-ornithine HCL
DL-ornithine monohydrochloride
DL-ornithine, hydrochloride
 
L -2,5-Diaminopentanoic acid
L-(-)-Ornithine
L-Ornithine
L-Ornithine hydrochloride
L-Ornithine hydrochloride (van)
L-Ornithine monohydrochloride
L-Ornithine, monohydrochloride
L-Ornithine-carboxy-14C hydrochloride
MonohydrochlorideDL-Ornithine
Monohydrochloridel-Ornithine
Ornithine DL-form HCL
Ornithine DL-form monohydrochloride
Ornithine hydrochloride
Ornithine hydrochloride (van)
Ornithine monohydrochloride
Ornithine, hydrochloride (1:1)
Ornithine, monohydrochloride
Poly-L-ornithine hydrochloride
36
CoumarinNutraceuticalPhase 41591-64-5323
Synonyms:
1, 2-Benzopyrone
2-Oxo-1,2-benzopyran
2-Oxo-2H-1-Benzopyran
2H-1-Benzopyran-2-one
2H-Benzo[b]pyran-2-one
2H-Chromen-2-one
2H-Chromen-2-one (ACD/Name 4.0)
5,6-Benzo-2-pyrone
Benzo-a-pyrone
Benzo-alpha-pyrone
 
Coumarin
Coumarine
Coumarinic anhydride
Cumarin
Kumarin
O-Hydroxycinnamic acid lactone
O-Hydroxycinnamic lactone
O-Hydroxyzimtsaure-lacton
Rattex
Tonka bean camphor
cis-O-Coumarinic acid lactone
{2H-Benzo[b]pyran-2-one}
37
BisoprololapprovedPhase 36366722-44-92405
Synonyms:
(+-)-1-((alpha-(2-Isopropoxyethoxy)-P-tolyl)oxy)-3-(isopropylamino)-2-propanol
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
66722-44-9
AB00514681
AC-18540
AC1L1DLQ
AKOS005110983
ARONIS24082
BISOPROLOL
BPBio1_000373
BSPBio_000339
Bisocor
Bisoprolol
Bisoprolol (USAN/INN)
Bisoprolol Fumarate
Bisoprolol Hemifumarate
Bisoprolol [USAN:BAN:INN]
Bisoprolol fumerate
Bisoprolol hemifumarate
Bisoprololum
Bisoprololum [Latin]
C06852
C18H31NO4
CHEBI:3127
CHEMBL645
CID2405
 
CL-297939
Cardicor
Concor
Condyline
Condylox
D02342
DB00612
Detensiel
EMD-33-512
EMD-33512
Emconcor
Emcor
Euradal
I01-7040
Isoten
L000133
LS-122509
MolPort-005-937-320
Monocor
NCGC00024868-02
NCGC00024868-03
NCGC00024868-04
NCGC00024868-05
Prestwick0_000330
Prestwick1_000330
Prestwick2_000330
Prestwick3_000330
SBB065120
SPBio_002260
Soloc
Soprol
UNII-Y41JS2NL6U
Zebeta
38
Seleniumapproved, vet_approvedPhase 31807782-49-2
Synonyms:
Selanediide
Selen
Selenide
Selenide(2-)
Selenio
 
Selenium
Selenium elemental
Selenium ion (Se2+)
Selenium metallicum
Selenium, elemental
Sélénium
39
Coal tarapprovedPhase 32028007-45-2
Synonyms:
 
Coal tars
Tar, coal
40SympatholyticsPhase 3580
41Autonomic AgentsPhase 310150
42Adrenergic beta-1 Receptor AntagonistsPhase 3364
43AntioxidantsPhase 33050
44Trace ElementsPhase 36001
45Sodium SelenitePhase 318
46Protective AgentsPhase 37443
47MicronutrientsPhase 36001
48MelarsoprolPhase 31
49
PentamidineapprovedPhase 241100-33-44735
Synonyms:
1,3-BIS(4-AMIDINOPHENOXY)PENTANE
1,3-Bis(4-amidinophenoxy)pentane
1,5-Bis(4-amidinophenoxy)pentane
100-33-4
4, 4'-Diamidinodiphenoxypentane
4,4'-(1,5-Pentanediylbis(oxy))bis-benzenecarboximidamide
4,4'-(Pentamethylenedioxy)dibenzamide
4,4'-(Pentamethylenedioxy)dibenzamidine
4,4'-Diamidino-.alpha.,.omega.-diphenoxypentane
4,4'-Diamidinodiphenoxypentane
4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
4-10-00-00447 (Beilstein Handbook Reference)
4-[5-(4-Carbamimidoylphenoxy)pentoxy]benzenecarboximidamide
6823-79-6
AB00053572
AC-12459
AC1L1IU8
AC1Q4YYD
BPBio1_000689
BRN 3159790
BSPBio_000625
BSPBio_001752
Benzenecarboximidamide, 4,4'-(1,5-pentanediylbis(oxy))bis- (9CI)
C07420
C19H24N4O2
CCRIS 3825
CHEBI:45081
CHEMBL55
CID4735
D08333
DB00738
EINECS 202-841-0
HMS2089J14
HSDB 7474
KBio3_001252
KBioGR_000879
LS-27566
Lomidine
Lomidine (TN)
MB 800
MB-800
MolPort-001-792-506
NCGC00179034-01
NCGC00179034-02
NCI60_042221
NSC 9921
 
NSC620107
NSC9921
Nebupent
Nebupent (*Isethionate)
Nebupent (as isethionate)
P,P'-(pentamethylenedioxy)dibenzamidine
PENTAM
PENTAMIDINE ISETHIONATE
PNT
Pentacarinat
Pentacarinat (*Isethionate)
Pentacarinat (as isethionate)
Pentam 300
Pentam 300 (*Isethionate)
Pentam 300 (as isethionate)
Pentamide
Pentamidin
Pentamidina
Pentamidina [DCIT]
Pentamidindiisetionat
Pentamidine
Pentamidine (INN)
Pentamidine Isethionate
Pentamidine Isethionate 2-Hydroxy-Ethanesulfonic Acid
Pentamidine [INN:BAN:DCF]
Pentamidine isetionate
Pentamidine mesylate
Pentamidinum
Pentamidinum [INN-Latin]
Pneumopent
Prestwick1_000553
Prestwick2_000553
Prestwick3_000553
RP 2512 (*Isethionate)
RP-2512
SPBio_000290
SPBio_002546
Spectrum2_000155
Spectrum3_000276
Spectrum4_000380
Spectrum5_001808
UNII-673LC5J4LQ
WLN: MUYZR DO5OR DYZUM
nchembio873-comp32
p,p'-(Pentamethylene-dioxy)bis-benzamidine
p,p'-(Pentamethylenedioxy)bis[benzamidine]
p,p'-(Pentamethylenedioxy)dibenzamidine
pentamidine
50
Posaconazoleapproved, investigational, vet_approvedPhase 256171228-49-2147912
Synonyms:
1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one
171228-49-2
177571-33-4
4-(p-(4-(p-(((3R,5R)-5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl)methoxy)phenyl)-1-piperazinyl)phenyl)-1-((1S,2S)-1-ethyl-2-hydroxypropyl)-delta(sup 2)-1,2,4-triazolin-5-one
4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
AC-1350
AC1L3W34
AC1LAHLQ
AKOS005145917
CHEBI:434337
CHEMBL1397
CHEMBL371938
CHEMBL371939
CID10532764
CID11520437
CID11542142
CID147912
CID468595
D02555
 
DB01263
HSDB 7421
LS-186118
LS-186988
LS-187630
MolPort-006-666-426
Noxafil
Noxafil (TN)
Noxafil, Posaconazole
Posaconazole
Posaconazole (USAN/INN)
Posaconazole SP
Posaconazole [USAN:INN:BAN]
Posaconazole in combination with MGCD290
S1257_Selleck
SCH-56592
SCH56592
Sch 56592
Spriafil
UNII-6TK1G07BHZ
X2N
posaconazole

Interventional clinical trials:

(show top 50)    (show all 67)
idNameStatusNCT IDPhase
1Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas DiseaseUnknown statusNCT01678599Phase 4
2Population Pharmacokinetics Study of Benznidazole in Children With Chagas'DiseaseUnknown statusNCT01549236Phase 4
3Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic PhaseCompletedNCT00906880Phase 4
4Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas DiseaseCompletedNCT01755403Phase 4
5Exercise Training in Chagas CardiomyopathyCompletedNCT01006473Phase 4
6A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
7Outcomes of an Anticoagulation Clinic in an University HospitalCompletedNCT01006486Phase 4
8Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)RecruitingNCT01650792Phase 4
9Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas DiseaseTerminatedNCT01539161Phase 4
10BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' DiseaseUnknown statusNCT00123916Phase 3
11Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African TrypanosomiasisCompletedNCT00146627Phase 3
12Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRCCompletedNCT01589289Phase 3
13Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Clinical TrialCompletedNCT02386358Phase 3
14Cardiac Rehabilitation in Chagas Heart FailureCompletedNCT02516293Phase 2, Phase 3
15Chagas Cardiomyopathy Bisoprolol Intervention Study: CharityCompletedNCT00323973Phase 3
16Prospective Study on Efficacy and Safety of SCYX-7158 in Patients Infected by Human African Trypanosomiasis Due to T.b. GambienseRecruitingNCT03087955Phase 2, Phase 3
17Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any StageRecruitingNCT03025789Phase 3
18CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)RecruitingNCT02369978Phase 2, Phase 3
19Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' DiseaseRecruitingNCT02625974Phase 3
20Selenium Treatment and Chagasic Cardiopathy (STCC)RecruitingNCT00875173Phase 3
21Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2Active, not recruitingNCT01685827Phase 2, Phase 3
22Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal StudyActive, not recruitingNCT02169557Phase 2, Phase 3
23Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal StudyActive, not recruitingNCT02184689Phase 2, Phase 3
24Physical Exercise Program in Chronic Chagas Heart DiseaseActive, not recruitingNCT02517632Phase 3
25Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, UgandaTerminatedNCT00489658Phase 2, Phase 3
26Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African TrypanosomiasisTerminatedNCT00330148Phase 3
27Cell Therapy in Chagas CardiomyopathyTerminatedNCT00349271Phase 3
28Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas DiseaseUnknown statusNCT01489228Phase 2
29Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00803933Phase 2
30A Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00802594Phase 2
31A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)CompletedNCT01377480Phase 2
32Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And BenznidazoleCompletedNCT01162967Phase 2
33Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas DiseaseRecruitingNCT02498782Phase 2
34Evaluation of G-CSF (Colony Stimulating Factor) in Patients With Chronic Chagas CardiomyopathyEnrolling by invitationNCT02154269Phase 2
35Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the FexinidazoleCompletedNCT00982904Phase 1
36Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158CompletedNCT01533961Phase 1
37Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market FormulationCompletedNCT02571062Phase 1
38Fexinidazole (1200mg) Bioavailability Under Different Food Intake ConditionsCompletedNCT01340157Phase 1
39Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT02606864Phase 1
40Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT01927224Phase 1
41Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With FoodTerminatedNCT01483170Phase 1
42Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on ElectrocardiogramUnknown statusNCT00453700
43Exercise Training in Patients With Chagasic Heart Disease Without Ventricular DysfunctionUnknown statusNCT02295215
44Renal Denervation in Patients With Heart Failure Secondary to Chagas DiseaseUnknown statusNCT02099903
45Improving Blood Safety and HIV Testing in BrazilUnknown statusNCT01681420
46Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)CompletedNCT01766830
47Abbott ESA Chagas Assay Post-Market StudyCompletedNCT01662362
48Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas DiseaseCompletedNCT02327052
49MicroRNAs as Biomarkers in Patients With Chagas DiseaseCompletedNCT01842880
50Syndecan-4 as a Biomarker in Patients With Chagas DiseaseCompletedNCT01842867

Search NIH Clinical Center for Trypanosomiasis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: trypanosomiasis

Genetic Tests for Trypanosomiasis

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Anatomical Context for Trypanosomiasis

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MalaCards organs/tissues related to Trypanosomiasis:

36
Testes, Brain, Heart, T cells, B cells, Endothelial, Myeloid

Publications for Trypanosomiasis

About this section

Articles related to Trypanosomiasis:

(show top 50)    (show all 620)
idTitleAuthorsYear
1
Erratum: Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis. (28074881)
2017
2
An overlooked horticultural crop, Smyrnium olusatrum, as a potential source of compounds effective against African trypanosomiasis. (28087440)
2017
3
Combatting African Animal Trypanosomiasis (AAT) in livestock: The potential role of trypanotolerance. (27369574)
2016
4
African Trypanosomiasis. (27974038)
2016
5
WC-9 a Lead Drug with Great Prospects for American Trypanosomiasis and Toxoplasmosis. (27290911)
2016
6
Human Leukocyte Antigen-G: A Promising Prognostic Marker of Disease Progression to Improve the Control of Human African Trypanosomiasis. (27470243)
2016
7
Human African Trypanosomiasis in the Kafue National Park, Zambia. (27196336)
2016
8
Human African Trypanosomiasis Encephalitis in the United States: Serial Magnetic Resonance Imaging. (27695600)
2016
9
Kynurenine Pathway Activation in Human African Trypanosomiasis. (28013248)
2016
10
Characteristics, behaviors and association between Human African Trypanosomiasis and HIV seropositivity among volunteer blood donors in a semi-rural area: A survey from Kikwit, the Democratic Republic of Congo. (27787206)
2016
11
Factors Influencing Passive Surveillance for T. b. rhodesiense Human African Trypanosomiasis in Uganda. (27212706)
2016
12
Beyond Tsetse - Implications for Research and Control of Human African Trypanosomiasis Epidemics. (26826783)
2016
13
Congenital Trypanosomiasis in Child Born in France to African Mother. (27088460)
2016
14
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: a Valuable Approach to Treat Human African Trypanosomiasis. (27156518)
2016
15
Forecasting Human African Trypanosomiasis Prevalences from Population Screening Data Using Continuous Time Models. (27657937)
2016
16
Food and pathogen adaptations in the Angolan Namib desert: Tracing the spread of lactase persistence and human African trypanosomiasis resistance into southwestern Africa. (27402285)
2016
17
Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis. (27936225)
2016
18
Assessment of animal African trypanosomiasis (AAT) vulnerability in cattle-owning communities of sub-Saharan Africa. (26825496)
2016
19
Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis. (27992217)
2016
20
Anterior uveitis as the first sign of human African trypanosomiasis: a case report. (27694095)
2016
21
Comparative evaluation of the nested ITS PCR against the 18S PCR-RFLP in a survey of bovine trypanosomiasis in Kwale County, Kenya. (27423733)
2016
22
Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species. (27167665)
2016
23
Neemazal Ar as a possible alternative control tool for malaria and African trypanosomiasis? (27146309)
2016
24
PREVALENCE OF AMERICAN TRYPANOSOMIASIS AND LEISHMANIASES IN DOMESTIC DOGS IN A RURAL AREA OF THE MUNICIPALITY OF SA8O JOA8O DO PIAUA8, PIAUA8 STATE, BRAZIL. (27828620)
2016
25
Human Trypanosomiasis in the Eastern Plains of Colombia: New Transmission Scenario. (26728765)
2016
26
Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis. (27941966)
2016
27
A Multi-Host Agent-Based Model for a Zoonotic, Vector-Borne Disease. A Case Study on Trypanosomiasis in Eastern Province, Zambia. (28027323)
2016
28
Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis. (27284970)
2016
29
Computer-Aided Drug Discovery Approaches against the Tropical Infectious Diseases Malaria, Tuberculosis, Trypanosomiasis, and Leishmaniasis. (27622945)
2016
30
Past and Ongoing Tsetse and Animal Trypanosomiasis Control Operations in Five African Countries: A Systematic Review. (28027299)
2016
31
Tsetse Flies (Glossina) as Vectors of Human African Trypanosomiasis: A Review. (27034944)
2016
32
Discovery of a Carbazole-Derived Lead Drug for Human African Trypanosomiasis. (27561392)
2016
33
The relationship of endotoxaemia to peripheral and central nervous system inflammatory responses in Human African Trypanosomiasis. (27894360)
2016
34
Impact of mass chemotherapy in domestic livestock for control of zoonotic T. b. rhodesiense human African trypanosomiasis in Eastern Uganda. (27570206)
2016
35
Human African trypanosomiasis diagnosis by peripheral blood smear review in a Spanish traveler. (27127825)
2016
36
Co-infection with Plasmodium berghei and Trypanosoma brucei increases severity of malaria and trypanosomiasis in mice. (27021269)
2016
37
Bug Smash, Bug Splash: A Case Report of an Unusual Transmission of American Trypanosomiasis with a Brief Review of the Literature. (28031550)
2016
38
Host Intracellular Signaling Events and Pro-inflammatory Cytokine Production in African Trypanosomiasis. (27242788)
2016
39
Performance of Microscopy for the Diagnosis of Malaria and Human African Trypanosomiasis by Diagnostic Laboratories in the Democratic Republic of the Congo: Results of a Nation-Wide External Quality Assessment. (26788725)
2016
40
Prevalence of tuberculosis, brucellosis and trypanosomiasis in cattle in Tanzania: a systematic review and meta-analysis. (27427190)
2016
41
Revisiting zoonotic human African trypanosomiasis control in Uganda. (26779716)
2016
42
Recent Updates on Development of Drug Molecules for Human African Trypanosomiasis. (27072715)
2016
43
Knowledge and prevalence of Human African Trypanosomiasis among residents of Kachia grazing reserve, Kachia local government area, Kaduna state, Nigeria, 2012. (27222686)
2016
44
Editorial (Thematic Issue: Therapeutic Interventions Against Trypanosomiasis). (27297226)
2016
45
West African Trypanosomiasis with Central Nervous System Involvement. (27582522)
2016
46
Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis. (26954675)
2016
47
Stakeholder Narratives on Trypanosomiasis, Their Effect on Policy and the Scope for One Health. (26658646)
2015
48
Human African trypanosomiasis in non-endemic countries. (25650203)
2015
49
Mathematical models of human african trypanosomiasis epidemiology. (25765194)
2015
50
Preventing the transmission of American trypanosomiasis and its spread into non-endemic countries. (26715535)
2015

Variations for Trypanosomiasis

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Expression for genes affiliated with Trypanosomiasis

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Search GEO for disease gene expression data for Trypanosomiasis.

Pathways for genes affiliated with Trypanosomiasis

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Pathways related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idSuper pathwaysScoreTop Affiliating Genes
19.9CXCL8, IL6, TNF
29.9CXCL8, IFNG, IL6
39.9CCL2, CXCL8, IL6
49.9HP, IL6, TNF
59.8IL1B, IL6, TNF
69.8CCL2, IFNG, IL1B
7
Show member pathways
9.8IFNG, IL2, TNF
89.8IL1B, IL4, IL6
99.7IFNG, IL2, IL4
109.7CCL5, CXCL8, TNF
119.7IL10, IL4, IL6, TNF
129.7IL10, IL1B, IL6, TNF
139.7CCL2, IFNG, IL1B, TNF
149.7CCL2, IFNG, IL1B, TNF
159.6CCL5, IL1B, IL6
169.6IFNG, IL10, IL2, IL6
179.6CXCL8, IL1B, IL6, TNF
189.6IFNG, IL2, IL6, TNF
199.6IL1B, IL4, IL6, TNF
20
Show member pathways
9.6IFNG, IL1B, IL4, IL6
219.6IFNG, IL10, IL2, IL4
229.6IFNG, IL10, IL2, IL4
239.6IFNG, IL1B, IL2, TNF
249.5IFNG, IL10, IL1B, IL6, TNF
259.5CXCL8, IL10, IL1B, IL6, TNF
26
Show member pathways
9.5CXCL8, IFNG, IL1B, IL6, TNF
279.4CCL2, CXCL8, IL1B, IL6, TNF
28
Show member pathways
9.4IFNG, IL10, IL1B, IL4, TNF
299.4IFNG, IL1B, IL4, IL6, TNF
30
Show member pathways
9.4IFNG, IL10, IL2, IL4, TNF
31
Show member pathways
9.4IFNG, IL10, IL2, IL4, IL6
329.4CALR, IFNG, IL1B, IL6, TNF
339.4CCL2, CCL3, IL1B, TNF
34
Show member pathways
9.4CXCL8, IFNG, IL2, IL4, TNF
359.3CXCL8, IFNG, IL2, IL4, IL6
369.3CXCL8, IFNG, IL10, IL1B, IL6, TNF
379.3CCL2, CCL5, IL1B, IL6, TNF
38
Show member pathways
9.2CCL2, CCL3, CCL5, CXCL8
399.2IFNG, IL10, IL2, IL4, IL6, TNF
40
Show member pathways
9.2CXCL8, IFNG, IL1B, IL4, IL6, TNF
419.2IFNG, IL10, IL1B, IL2, IL6, TNF
42
Show member pathways
9.2IFNG, IL10, IL1B, IL2, IL6, TNF
43
Show member pathways
9.2CCL3, IFNG, IL10, IL2, TNF
44
Show member pathways
9.2CCL3, CXCL8, IFNG, IL1B, IL6
459.2CCL3, CXCL8, IFNG, IL1B, IL6
46
Show member pathways
9.2CXCL8, IFNG, IL1B, IL2, IL6, TNF
479.2CXCL8, IL10, IL1B, IL6, TF, TNF
489.1CCL2, CXCL8, IFNG, IL10, IL1B, IL6
49
Show member pathways
9.1CCL5, CXCL8, IFNG, IL1B, IL6, TNF
50
Show member pathways
9.1CCL2, CCL5, CXCL8, IL1B, IL6, TNF

GO Terms for genes affiliated with Trypanosomiasis

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Cellular components related to Trypanosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:000989710.2CALR, IFNG, IL4, IL6, TNF
2endoplasmic reticulum lumenGO:000578810.0ALB, APOL1, CALR, IL6, TF
3blood microparticleGO:00725629.8ALB, APOL1, HP, HPR, TF
4extracellular regionGO:00055766.7ALB, APOL1, CALR, CCL2, CCL3, CCL5
5extracellular spaceGO:00056156.4ALB, APOL1, CALR, CCL2, CCL3, CCL5

Biological processes related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 80)
idNameGO IDScoreTop Affiliating Genes
1endothelial cell apoptotic processGO:007257710.9IL10, TNF
2negative regulation of cytokine secretion involved in immune responseGO:000274010.9IL10, TNF
3epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.9IL6, TNF
4negative regulation of lipid storageGO:001088810.9IL6, TNF
5neutrophil apoptotic processGO:000178110.9IFNG, IL6
6receptor biosynthetic processGO:003280010.8IL10, TNF
7positive regulation of vitamin D biosynthetic processGO:006055710.8IFNG, TNF
8positive regulation of mononuclear cell migrationGO:007167710.8IL4, TNF
9positive regulation of fever generationGO:003162210.8IL1B, TNF
10polyamine metabolic processGO:000659510.8AMD1, ODC1
11positive regulation of interleukin-6 biosynthetic processGO:004541010.8IFNG, IL1B
12regulation of vascular endothelial growth factor productionGO:001057410.8CCL2, IL6
13negative regulation of growth of symbiont in hostGO:004413010.7IFNG, IL10, TNF
14regulation of isotype switchingGO:004519110.7IL10, IL4
15cellular response to estradiol stimulusGO:007139210.7CCL2, IL10, IL6
16regulation of establishment of endothelial barrierGO:190314010.7IL1B, TNF
17regulation of defense response to virus by hostGO:005069110.7IFNG, IL1B
18negative regulation of T-helper 17 cell differentiationGO:200032010.7IL2, IL4
19negative regulation of T cell apoptotic processGO:007023310.7CCL5, IDO1
20neutrophil activationGO:004211910.7CCL5, CXCL8
21positive regulation of T cell apoptotic processGO:007023410.7CCL5, IDO1
22positive regulation of MHC class II biosynthetic processGO:004534810.6IFNG, IL10, IL4
23positive regulation of calcidiol 1-monooxygenase activityGO:006055910.6IFNG, IL1B, TNF
24astrocyte cell migrationGO:004361510.6CCL2, CCL3
25positive regulation of heterotypic cell-cell adhesionGO:003411610.6IL10, IL1B, TNF
26positive regulation of membrane protein ectodomain proteolysisGO:005104410.6IFNG, IL1B, TNF
27positive regulation of interleukin-6 productionGO:003275510.6IL1B, IL6, TNF
28humoral immune responseGO:000695910.5CCL2, IFNG, IL6, TNF
29positive regulation of phagocytosisGO:005076610.5CALR, IL1B, TNF
30defense response to bacteriumGO:004274210.5HP, IFNG, IL10, TNF
31positive regulation of isotype switching to IgG isotypesGO:004830410.5IFNG, IL2, IL4
32cellular response to fibroblast growth factor stimulusGO:004434410.5CCL2, CCL5, CXCL8
33positive regulation of interferon-gamma productionGO:003272910.5IL1B, IL2, TNF
34positive regulation of smooth muscle cell proliferationGO:004866110.5CCL5, IL6, TNF
35defense response to protozoanGO:004283210.5IFNG, IL10, IL4, IL6
36extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.5IL1B, IL2, IL4
37eosinophil chemotaxisGO:004824510.4CCL3, CCL5
38positive regulation of nitric oxide biosynthetic processGO:004542910.4IFNG, IL1B, IL6, TNF
39positive regulation of natural killer cell chemotaxisGO:200050310.4CCL3, CCL5
40positive regulation of chemokine biosynthetic processGO:004508010.4IFNG, IL1B, IL4, TNF
41response to glucocorticoidGO:005138410.4CCL2, IL10, IL6, TNF
42positive regulation of tumor necrosis factor productionGO:003276010.4CCL2, CCL3, IFNG
43positive regulation of cell adhesionGO:004578510.3CCL2, CCL5, IFNG, TNF
44response to cytokineGO:003409710.3CCL5, IL4, IL6
45cellular protein metabolic processGO:004426710.3ALB, APOL1, IL6, TF
46cell chemotaxisGO:006032610.3CCL2, CCL3, CCL5
47cellular response to interferon-gammaGO:007134610.3CCL2, CCL3, CCL5
48negative regulation of cell proliferationGO:000828510.3CXCL8, IFNG, IL10, IL1B, IL6
49macrophage chemotaxisGO:004824610.2CCL2, CCL3, CCL5
50positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.2IL10, IL1B, IL4, IL6, TNF

Molecular functions related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1CCR1 chemokine receptor bindingGO:003172610.3CCL3, CCL5
2CCR5 chemokine receptor bindingGO:003173010.3CCL3, CCL5
3hemoglobin bindingGO:003049210.0HP, HPR
4chemokine activityGO:00080099.9CCL2, CCL3, CCL5, CXCL8
5growth factor activityGO:00080839.8IL10, IL2, IL4, IL6
6phospholipase activator activityGO:00160049.6CCL3, CCL5
7cytokine activityGO:00051258.3CCL2, CCL3, CCL5, CXCL8, IFNG, IL10

Sources for Trypanosomiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet