MCID: TRY001
MIFTS: 52

Trypanosomiasis malady

Category: Infectious diseases

Aliases & Classifications for Trypanosomiasis

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Aliases & Descriptions for Trypanosomiasis:

Name: Trypanosomiasis 11 49 38 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:10113
ICD1029 B57.2
ICD9CM31 086, 086.9
MeSH38 D014352

Summaries for Trypanosomiasis

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Disease Ontology:11 A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.

MalaCards based summary: Trypanosomiasis is related to babesiosis and louping ill, and has symptoms including trypanosomal chancre An important gene associated with Trypanosomiasis is APOL1 (Apolipoprotein L1), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Jak/STAT Signaling Pathway. The drugs pentamidine isethionate and pentamidine have been mentioned in the context of this disorder. Affiliated tissues include testes, heart and brain, and related mouse phenotypes are liver/biliary system and digestive/alimentary.

Wikipedia:70 Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic... more...

Related Diseases for Trypanosomiasis

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Diseases related to Trypanosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 388)
idRelated DiseaseScoreTop Affiliating Genes
1babesiosis30.5IL10, IL1B, IL6, TNF
2louping ill29.6CCL2, CXCL8, ICAM1, IFNG, IL2, TNF
3malaria27.7ALB, CCL2, CCL3, CXCL8, HP, ICAM1
4sleeping sickness12.1
5chagas disease11.9
6trypanosomiasis, human east-african11.8
7trypanosomiasis, human west-african11.8
8piepkorn karp hickok syndrome10.8IL10, TNF
9thyroid malformation10.8IL1B, TNF
10panner disease10.7IFNG, IL6, TNF
11ethmoid sinus adenoid cystic carcinoma10.7IL10, IL6, TNF
12hernia of ovary and fallopian tube10.7IFNG, IL10, TNF
13baetz-greenwalt syndrome10.7IFNG, IL1B, TNF
14herpangina10.7IFNG, IL10, IL6
15sensorineural hearing loss10.7IFNG, IL10, TNF
16idiopathic neutropenia10.7IFNG, IL10, IL6
17scrotum paget's disease10.7IL1B, IL6, TNF
18hypothyroidism10.7IL1B, IL6, TNF
19benign adult familial myoclonic epilepsy10.7CXCL8, IL10, IL6
20autoimmune polyendocrine syndrome10.7IL1B, IL6, TNF
21primary biliary cirrhosis10.7IL10, IL6, TNF
22antigen-peptide-transporter 2 deficiency10.7CCL2, IL6, TNF
23scarlet fever10.7IL1B, IL6, TNF
24non-secretory myeloma10.7IL1B, IL6, TNF
25opiate dependence10.7CCL2, IFNG, IL6
26hypospadias, hypertelorism, upper lid coloboma, and mixed-type hearing loss10.7IL1B, TNF
27corneal deposit10.7CXCL8, IL1B, IL6
28tarsal tunnel syndrome10.7CXCL8, IL1B, IL6
29marchiafava bignami disease10.7CXCL8, IL10, IL6
30pernicious anemia10.7IDO1, IL10, IL1B
31thoracic aortic aneurysm10.7IL1B, IL6, TNF
32foodborne botulism10.7IL1B, IL6, TNF
33distal monosomy 9p10.7CXCL8, IFNG, IL10
34cat-scratch disease10.6IDO1, IL10, IL1B
35melioidosis10.6IFNG, IL10, IL6
36paraphimosis10.6CXCL8, IL1B, TNF
37spastic paraplegia-paget disease of bone syndrome10.6ICAM1, IL1B, TNF
38cytomegalovirus retinitis10.6CCL2, CXCL8, ICAM1
39keloids10.6IL1B, IL6, TNF
40mechanical lagophthalmos10.6CXCL8, IL6, TNF
41inflammatory spondylopathy10.6CXCL8, IL1B, IL6
42gasserian ganglion meningioma10.6CCL2, CXCL8, IL6
43ocular cancer10.6CXCL8, IL1B, IL6
44mastocytosis cutaneous with short stature conductive hearing loss and microtia10.6IFNG, IL10, IL6, TNF
45hemophagocytic lymphohistiocytosis10.6IFNG, IL10, IL6, TNF
46myoclonus epilepsy10.6IFNG, IL4
47leukostasis10.6IFNG, IL10, IL6, TNF
48staphyloenterotoxemia10.6CXCL8, IL6, TNF
49west nile fever10.6CCL2, ICAM1, IL6
50hereditary renal cell carcinoma10.6CCL2, ICAM1, IL6

Graphical network of the top 20 diseases related to Trypanosomiasis:



Diseases related to trypanosomiasis

Symptoms for Trypanosomiasis

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UMLS symptoms related to Trypanosomiasis:


trypanosomal chancre

Drugs & Therapeutics for Trypanosomiasis

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Drugs for Trypanosomiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 72)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EnalaprilatapprovedPhase 412076420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
Enalaprilat
Enalaprilat (USP)
 
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline—water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalaprilat dihydrate
enalaprilat hydrate
enalprilat hydrate
enalprilate hydrate
2
WarfarinapprovedPhase 445481-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
3
Enalaprilapproved, vet_approvedPhase 412075847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
4
Carvedilolapproved, investigationalPhase 416372956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
5
Aspirinapproved, vet_approvedPhase 4111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
6Immunosuppressive AgentsPhase 4, Phase 3, Phase 212770
7Antiparasitic AgentsPhase 4, Phase 3, Phase 2, Phase 12127
8BenzonidazolePhase 4, Phase 3, Phase 212
9Antiprotozoal AgentsPhase 4, Phase 3, Phase 2, Phase 11986
10Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
11
protease inhibitorsPhase 45320
Synonyms:
 
protease inhibitors
12Neurotransmitter AgentsPhase 4, Phase 317734
13Vasodilator AgentsPhase 43438
14Peripheral Nervous System AgentsPhase 4, Phase 322776
15NifurtimoxPhase 4, Phase 3, Phase 2, Phase 112
16Adrenergic alpha-AntagonistsPhase 4727
17AnticoagulantsPhase 42516
18Natriuretic Peptide, BrainPhase 4178
19HIV Protease InhibitorsPhase 45319
20Adrenergic beta-AntagonistsPhase 4, Phase 31154
21Adrenergic AntagonistsPhase 4, Phase 31535
22Antihypertensive AgentsPhase 4, Phase 34095
23Angiotensin-Converting Enzyme InhibitorsPhase 4711
24Adrenergic AgentsPhase 4, Phase 35140
25Adrenergic alpha-1 Receptor AntagonistsPhase 4470
26Antirheumatic AgentsPhase 410627
27Fibrinolytic AgentsPhase 42317
28AntipyreticsPhase 41534
29Cyclooxygenase InhibitorsPhase 42778
30Platelet Aggregation InhibitorsPhase 42419
31Anti-Inflammatory Agents, Non-SteroidalPhase 44295
32Analgesics, Non-NarcoticPhase 46260
33AnalgesicsPhase 411287
34Anti-Inflammatory AgentsPhase 410355
35
OrnithineNutraceuticalPhase 4, Phase 3, Phase 2693184-13-26262, 389
Synonyms:
(+)-S-Ornithine
(+/-)-2,5-Diaminopentanoic acid monohydrochloride
(S)-2,5-Diaminopentanoate
(S)-2,5-Diaminopentanoic acid
(S)-Ornithine
(S)-a,D-Diaminovalerate
(S)-a,D-Diaminovaleric acid
2,5-Diaminopentanoic acid hydrochloride
5-Amino-L-Norvaline
D -2,5-Diaminopentanoic acid
D-Ornithine
DL -2,5-Diaminopentanoic acid
DL-ornithine
DL-ornithine HCL
DL-ornithine monohydrochloride
DL-ornithine, hydrochloride
 
L -2,5-Diaminopentanoic acid
L-(-)-Ornithine
L-Ornithine
L-Ornithine hydrochloride
L-Ornithine hydrochloride (van)
L-Ornithine monohydrochloride
L-Ornithine, monohydrochloride
L-Ornithine-carboxy-14C hydrochloride
MonohydrochlorideDL-Ornithine
Monohydrochloridel-Ornithine
Ornithine DL-form HCL
Ornithine DL-form monohydrochloride
Ornithine hydrochloride
Ornithine hydrochloride (van)
Ornithine monohydrochloride
Ornithine, hydrochloride (1:1)
Ornithine, monohydrochloride
Poly-L-ornithine hydrochloride
36
CoumarinNutraceuticalPhase 41491-64-5323
Synonyms:
1, 2-Benzopyrone
2-Oxo-1,2-benzopyran
2-Oxo-2H-1-Benzopyran
2H-1-Benzopyran-2-one
2H-Benzo[b]pyran-2-one
2H-Chromen-2-one
2H-Chromen-2-one (ACD/Name 4.0)
5,6-Benzo-2-pyrone
Benzo-a-pyrone
Benzo-alpha-pyrone
 
Coumarin
Coumarine
Coumarinic anhydride
Cumarin
Kumarin
O-Hydroxycinnamic acid lactone
O-Hydroxycinnamic lactone
O-Hydroxyzimtsaure-lacton
Rattex
Tonka bean camphor
cis-O-Coumarinic acid lactone
{2H-Benzo[b]pyran-2-one}
37
BisoprololapprovedPhase 36266722-44-92405
Synonyms:
(+-)-1-((alpha-(2-Isopropoxyethoxy)-P-tolyl)oxy)-3-(isopropylamino)-2-propanol
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
66722-44-9
AB00514681
AC-18540
AC1L1DLQ
AKOS005110983
ARONIS24082
BISOPROLOL
BPBio1_000373
BSPBio_000339
Bisocor
Bisoprolol
Bisoprolol (USAN/INN)
Bisoprolol Fumarate
Bisoprolol Hemifumarate
Bisoprolol [USAN:BAN:INN]
Bisoprolol fumerate
Bisoprolol hemifumarate
Bisoprololum
Bisoprololum [Latin]
C06852
C18H31NO4
CHEBI:3127
CHEMBL645
CID2405
 
CL-297939
Cardicor
Concor
Condyline
Condylox
D02342
DB00612
Detensiel
EMD-33-512
EMD-33512
Emconcor
Emcor
Euradal
I01-7040
Isoten
L000133
LS-122509
MolPort-005-937-320
Monocor
NCGC00024868-02
NCGC00024868-03
NCGC00024868-04
NCGC00024868-05
Prestwick0_000330
Prestwick1_000330
Prestwick2_000330
Prestwick3_000330
SBB065120
SPBio_002260
Soloc
Soprol
UNII-Y41JS2NL6U
Zebeta
38
Coal tarapprovedPhase 31918007-45-2
Synonyms:
 
Coal tars
Tar, coal
39SympatholyticsPhase 3555
40Autonomic AgentsPhase 39774
41Adrenergic beta-1 Receptor AntagonistsPhase 3350
42
SeleniumPhase 31757782-49-2
Synonyms:
Selanediide
Selenide
 
Selenide(2-)
Selenium
Selenium ion (Se2+)
43Trace ElementsPhase 35802
44Sodium SelenitePhase 317
45Protective AgentsPhase 37190
46MicronutrientsPhase 35802
47AntioxidantsPhase 32928
48MelarsoprolPhase 31
49
PentamidineapprovedPhase 240100-33-44735
Synonyms:
1,3-BIS(4-AMIDINOPHENOXY)PENTANE
1,3-Bis(4-amidinophenoxy)pentane
1,5-Bis(4-amidinophenoxy)pentane
100-33-4
4, 4'-Diamidinodiphenoxypentane
4,4'-(1,5-Pentanediylbis(oxy))bis-benzenecarboximidamide
4,4'-(Pentamethylenedioxy)dibenzamide
4,4'-(Pentamethylenedioxy)dibenzamidine
4,4'-Diamidino-.alpha.,.omega.-diphenoxypentane
4,4'-Diamidinodiphenoxypentane
4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
4-10-00-00447 (Beilstein Handbook Reference)
4-[5-(4-Carbamimidoylphenoxy)pentoxy]benzenecarboximidamide
6823-79-6
AB00053572
AC-12459
AC1L1IU8
AC1Q4YYD
BPBio1_000689
BRN 3159790
BSPBio_000625
BSPBio_001752
Benzenecarboximidamide, 4,4'-(1,5-pentanediylbis(oxy))bis- (9CI)
C07420
C19H24N4O2
CCRIS 3825
CHEBI:45081
CHEMBL55
CID4735
D08333
DB00738
EINECS 202-841-0
HMS2089J14
HSDB 7474
KBio3_001252
KBioGR_000879
LS-27566
Lomidine
Lomidine (TN)
MB 800
MB-800
MolPort-001-792-506
NCGC00179034-01
NCGC00179034-02
NCI60_042221
NSC 9921
 
NSC620107
NSC9921
Nebupent
Nebupent (*Isethionate)
Nebupent (as isethionate)
P,P'-(pentamethylenedioxy)dibenzamidine
PENTAM
PENTAMIDINE ISETHIONATE
PNT
Pentacarinat
Pentacarinat (*Isethionate)
Pentacarinat (as isethionate)
Pentam 300
Pentam 300 (*Isethionate)
Pentam 300 (as isethionate)
Pentamide
Pentamidin
Pentamidina
Pentamidina [DCIT]
Pentamidindiisetionat
Pentamidine
Pentamidine (INN)
Pentamidine Isethionate
Pentamidine Isethionate 2-Hydroxy-Ethanesulfonic Acid
Pentamidine [INN:BAN:DCF]
Pentamidine isetionate
Pentamidine mesylate
Pentamidinum
Pentamidinum [INN-Latin]
Pneumopent
Prestwick1_000553
Prestwick2_000553
Prestwick3_000553
RP 2512 (*Isethionate)
RP-2512
SPBio_000290
SPBio_002546
Spectrum2_000155
Spectrum3_000276
Spectrum4_000380
Spectrum5_001808
UNII-673LC5J4LQ
WLN: MUYZR DO5OR DYZUM
nchembio873-comp32
p,p'-(Pentamethylene-dioxy)bis-benzamidine
p,p'-(Pentamethylenedioxy)bis[benzamidine]
p,p'-(Pentamethylenedioxy)dibenzamidine
pentamidine
50
Posaconazoleapproved, investigational, vet_approvedPhase 253171228-49-2147912
Synonyms:
1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one
171228-49-2
177571-33-4
4-(p-(4-(p-(((3R,5R)-5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl)methoxy)phenyl)-1-piperazinyl)phenyl)-1-((1S,2S)-1-ethyl-2-hydroxypropyl)-delta(sup 2)-1,2,4-triazolin-5-one
4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
AC-1350
AC1L3W34
AC1LAHLQ
AKOS005145917
CHEBI:434337
CHEMBL1397
CHEMBL371938
CHEMBL371939
CID10532764
CID11520437
CID11542142
CID147912
CID468595
D02555
 
DB01263
HSDB 7421
LS-186118
LS-186988
LS-187630
MolPort-006-666-426
Noxafil
Noxafil (TN)
Noxafil, Posaconazole
Posaconazole
Posaconazole (USAN/INN)
Posaconazole SP
Posaconazole [USAN:INN:BAN]
Posaconazole in combination with MGCD290
S1257_Selleck
SCH-56592
SCH56592
Sch 56592
Spriafil
UNII-6TK1G07BHZ
X2N
posaconazole

Interventional clinical trials:

(show top 50)    (show all 65)
idNameStatusNCT IDPhase
1Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas DiseaseUnknown statusNCT01678599Phase 4
2Population Pharmacokinetics Study of Benznidazole in Children With Chagas'DiseaseUnknown statusNCT01549236Phase 4
3Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic PhaseCompletedNCT00906880Phase 4
4Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas DiseaseCompletedNCT01755403Phase 4
5Exercise Training in Chagas CardiomyopathyCompletedNCT01006473Phase 4
6A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
7Outcomes of an Anticoagulation Clinic in an University HospitalCompletedNCT01006486Phase 4
8Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)RecruitingNCT01650792Phase 4
9Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas DiseaseTerminatedNCT01539161Phase 4
10BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' DiseaseUnknown statusNCT00123916Phase 3
11Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African TrypanosomiasisCompletedNCT00146627Phase 3
12Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRCCompletedNCT01589289Phase 3
13Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Clinical TrialCompletedNCT02386358Phase 3
14Cardiac Rehabilitation in Chagas Heart FailureCompletedNCT02516293Phase 2, Phase 3
15Chagas Cardiomyopathy Bisoprolol Intervention Study: CharityCompletedNCT00323973Phase 3
16Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any StageRecruitingNCT03025789Phase 3
17CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)RecruitingNCT02369978Phase 2, Phase 3
18Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' DiseaseRecruitingNCT02625974Phase 3
19Selenium Treatment and Chagasic Cardiopathy (STCC)RecruitingNCT00875173Phase 3
20Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2Active, not recruitingNCT01685827Phase 2, Phase 3
21Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal StudyActive, not recruitingNCT02169557Phase 2, Phase 3
22Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal StudyActive, not recruitingNCT02184689Phase 2, Phase 3
23Physical Exercise Program in Chronic Chagas Heart DiseaseActive, not recruitingNCT02517632Phase 3
24Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, UgandaTerminatedNCT00489658Phase 2, Phase 3
25Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African TrypanosomiasisTerminatedNCT00330148Phase 3
26Cell Therapy in Chagas CardiomyopathyTerminatedNCT00349271Phase 3
27Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas DiseaseUnknown statusNCT01489228Phase 2
28Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00803933Phase 2
29A Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00802594Phase 2
30A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)CompletedNCT01377480Phase 2
31Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And BenznidazoleCompletedNCT01162967Phase 2
32Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas DiseaseRecruitingNCT02498782Phase 2
33Evaluation of G-CSF (Colony Stimulating Factor) in Patients With Chronic Chagas CardiomyopathyEnrolling by invitationNCT02154269Phase 2
34Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the FexinidazoleCompletedNCT00982904Phase 1
35Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158CompletedNCT01533961Phase 1
36Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market FormulationCompletedNCT02571062Phase 1
37Fexinidazole (1200mg) Bioavailability Under Different Food Intake ConditionsCompletedNCT01340157Phase 1
38Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT02606864Phase 1
39Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' PatientsCompletedNCT01927224Phase 1
40Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With FoodTerminatedNCT01483170Phase 1
41Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on ElectrocardiogramUnknown statusNCT00453700
42Exercise Training in Patients With Chagasic Heart Disease Without Ventricular DysfunctionUnknown statusNCT02295215
43Renal Denervation in Patients With Heart Failure Secondary to Chagas DiseaseUnknown statusNCT02099903
44Improving Blood Safety and HIV Testing in BrazilUnknown statusNCT01681420
45Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)CompletedNCT01766830
46Abbott ESA Chagas Assay Post-Market StudyCompletedNCT01662362
47Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas DiseaseCompletedNCT02327052
48MicroRNAs as Biomarkers in Patients With Chagas DiseaseCompletedNCT01842880
49Syndecan-4 as a Biomarker in Patients With Chagas DiseaseCompletedNCT01842867
50Galectin-3 as a Biomarker in Patients With Chagas DiseaseCompletedNCT01842854

Search NIH Clinical Center for Trypanosomiasis

Inferred drug relations via UMLS67/NDF-RT45:


Cochrane evidence based reviews: trypanosomiasis

Genetic Tests for Trypanosomiasis

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Anatomical Context for Trypanosomiasis

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MalaCards organs/tissues related to Trypanosomiasis:

35
Testes, Heart, Brain, T cells, B cells, Endothelial, Myeloid

Animal Models for Trypanosomiasis or affiliated genes

About this section

MGI Mouse Phenotypes related to Trypanosomiasis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.4ALB, HP, IFNG, IL10, IL2, IL4
2MP:00053819.4ALB, ICAM1, IFNG, IL10, IL2, IL4
3MP:00053878.8CCL2, HP, ICAM1, IDO1, IFNG, IL10
4MP:00053978.7HP, ICAM1, IDO1, IFNG, IL10, IL1B
5MP:00053848.4ALB, CALR, HP, ICAM1, IDO1, IFNG
6MP:00020068.3ALB, HP, ICAM1, IFNG, IL10, IL1B
7MP:00053768.0ALB, CALR, HP, ICAM1, IDO1, IFNG
8MP:00107687.9ALB, CALR, HP, ICAM1, IFNG, IL10

Publications for Trypanosomiasis

About this section

Articles related to Trypanosomiasis:

(show top 50)    (show all 620)
idTitleAuthorsYear
1
Human Leukocyte Antigen-G: A Promising Prognostic Marker of Disease Progression to Improve the Control of Human African Trypanosomiasis. (27470243)
2016
2
Recent Updates on Development of Drug Molecules for Human African Trypanosomiasis. (27072715)
2016
3
West African Trypanosomiasis with Central Nervous System Involvement. (27582522)
2016
4
Trypanosomiasis-induced megacolon illustrates how myenteric neurons modulate the risk for colon cancer in rats and humans. (25884710)
2015
5
Human African trypanosomiasis in non-endemic countries. (25650203)
2015
6
Oral Multicomponent DNA Vaccine Delivered by Attenuated Salmonella Elicited Immunoprotection Against American Trypanosomiasis. (25160983)
2014
7
Social factors affecting seasonal variation in bovine trypanosomiasis on the Jos Plateau, Nigeria. (24172046)
2013
8
HLA-G 3' UTR-2 haplotype is associated with Human African trypanosomiasis susceptibility. (23541412)
2013
9
Modeling the control of trypanosomiasis using trypanocides or insecticide-treated livestock. (22616017)
2012
10
Human African trypanosomiasis in South Sudan: how can we prevent a new epidemic? (22666506)
2012
11
A review of QSAR studies to discover new drug-like compounds actives against leishmaniasis and trypanosomiasis. (22352913)
2012
12
Trypanosomiasis in an infant from India. (21715739)
2011
13
Transmission of human African trypanosomiasis in the Komo-Mondah focus, Gabon. (22121444)
2011
14
African trypanosomiasis. (21609334)
2011
15
Tsetse fly control and trypanosomiasis in Africa, quo vadis? (21104211)
2011
16
Identification of Selective Inhibitors of Phosphofructokinase as Lead Compounds Against Trypanosomiasis (24027803)
2010
17
Novel biomarkers for late-stage human African trypanosomiasis--the search goes on. (20519588)
2010
18
Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation. (20605052)
2010
19
Atypical human trypanosomiasis: a neglected disease or just an unlucky accident? (19162551)
2009
20
Justice where justice is due: A posthumous Nobel Prize to Carlos Chagas (1879-1934), the discoverer of American Trypanosomiasis (Chagas' disease). (19185367)
2009
21
Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis. (19828449)
2009
22
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. (19289530)
2009
23
Regulatory T cells prevent control of experimental African trypanosomiasis. (18250461)
2008
24
Contributions of experimental mouse models to the understanding of African trypanosomiasis. (18684669)
2008
25
American trypanosomiasis in dogs from an urban and rural area of Yucatan, Mexico. (18597661)
2008
26
Novel markers for treatment outcome in late-stage Trypanosoma brucei gambiense trypanosomiasis. (18494605)
2008
27
Hypocretin and human African trypanosomiasis. (18363311)
2008
28
Knowledge, behaviours, practices and beliefs regarding Human African Trypanosomiasis (HAT) among inhabitants of Kinshasa (Democratic Republic of Congo). (19359235)
2008
29
Sleeping glands? - The role of endocrine disorders in sleeping sickness (T.b. gambiense Human African Trypanosomiasis). (17767911)
2007
30
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system. (16965857)
2007
31
A systematic strategy for large-scale analysis of genotype phenotype correlations: identification of candidate genes involved in African trypanosomiasis. (17709344)
2007
32
Development and evaluation of new diagnostic tests for human African trypanosomiasis. (16671230)
2006
33
Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor. (16604085)
2006
34
Immunology and immunopathology of African trypanosomiasis. (17143404)
2006
35
Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis. (16080099)
2005
36
Disruptions of ultradian and circadian organization of core temperature in a rat model of African trypanosomiasis using periodogram techniques on detrended data. (16021841)
2005
37
Congenital trypanosomiasis. (15537729)
2004
38
American trypanosomiasis in central Mexico: Trypanosoma cruzi infection in triatomine bugs and mammals from the municipality of Jiutepec in the state of Morelos. (15257803)
2004
39
Antibodies directed against nitrosylated neoepitopes in sera of patients with human African trypanosomiasis. (15482403)
2004
40
A bloodstream Trypanosoma congolense sialidase could be involved in anemia during experimental trypanosomiasis. (12869528)
2003
41
American trypanosomiasis (Chagas' disease) and the role of molecular epidemiology in guiding control strategies. (12829559)
2003
42
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. (12743807)
2003
43
Current chemotherapy of human African trypanosomiasis. (12811544)
2003
44
Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis. (11348533)
2001
45
Are there new approaches to roll back trypanosomiasis? (11348526)
2001
46
An evaluation of the reactivity of the card agglutination test for trypanosomiasis (CATT) reagent in the Fontem sleeping sickness focus, Cameroon. (7839945)
1994
47
Human African trypanosomiasis (T.b. gambiense): a study of 16 fatal cases of sleeping sickness with some observations on acute reactive arsenical encephalopathy. (3703156)
1986
48
Field evaluation of Cellognost indirect haemagglutination test in the diagnosis of human trypanosomiasis (sleeping sickness) in Kura local government area of Kano State, Nigeria. (2862781)
1985
49
The public health significance of trypanosomiasis (sleeping sickness) in Nigeria. (4055267)
1985
50
Immunosuppression in experimental trypanosomiasis: effects of Trypanosoma brucei on immunization against louping-ill virus and lymphocytic choriomeningitis virus. (232108)
1979

Variations for Trypanosomiasis

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Expression for genes affiliated with Trypanosomiasis

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Search GEO for disease gene expression data for Trypanosomiasis.

Pathways for genes affiliated with Trypanosomiasis

About this section

Pathways related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show all 48)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL1B, IL4, IL6
29.7IFNG, IL10, IL2, IL6
39.7IL10, IL1B, IL6, TNF
49.6CCL2, IFNG, IL1B, TNF
59.6CXCL8, IL1B, IL6, TNF
69.6IFNG, IL10, IL2, IL4
79.6IFNG, IL10, IL2, IL4
89.5HP, ICAM1, IL6, TNF
99.5IFNG, IL10, IL1B, IL6, TNF
109.5CXCL8, IL10, IL1B, IL6, TNF
11
Show member pathways
9.4CXCL8, IFNG, IL1B, IL6, TNF
12
Show member pathways
9.4IFNG, IL10, IL1B, IL4, TNF
13
Show member pathways
9.4CXCL8, IFNG, IL2, IL4, TNF
149.4CALR, IFNG, IL1B, IL6, TNF
159.4ICAM1, IL10, IL4, IL6, TNF
169.3CCL2, ICAM1, IL1B, IL6, TNF
179.3CXCL8, IFNG, IL10, IL1B, IL6, TNF
189.2IFNG, IL10, IL2, IL4, IL6, TNF
19
Show member pathways
9.2CCL3, IFNG, IL10, IL2, TNF
209.2IFNG, IL10, IL1B, IL2, IL6, TNF
21
Show member pathways
9.2IFNG, IL10, IL1B, IL2, IL6, TNF
22
Show member pathways
9.2CXCL8, IFNG, IL1B, IL4, IL6, TNF
239.2CCL3, CXCL8, IFNG, IL1B, IL6
24
Show member pathways
9.2CCL3, CXCL8, IFNG, IL1B, IL6
259.1CXCL8, IL10, IL1B, IL6, TF, TNF
269.1CXCL8, ICAM1, IFNG, IL2, IL6, TNF
279.1CCL2, CXCL8, ICAM1, IL1B, IL6, TNF
28
Show member pathways
9.0CCL3, IFNG, IL1B, IL2, IL4
299.0CXCL8, ICAM1, IFNG, IL2, IL4, IL6
30
Show member pathways
9.0CCL2, IFNG, IL10, IL1B, IL2, IL6
319.0CCL2, CCL3, ICAM1, IL1B, TNF
32
Show member pathways
9.0ALB, APOL1, CALR, HP, HPR
339.0IFNG, IL10, IL1B, IL2, IL4, IL6
34
Show member pathways
9.0IFNG, IL10, IL1B, IL2, IL4, IL6
358.8CCL2, IDO1, IFNG, IL10, IL1B, IL2
36
Show member pathways
8.8CXCL8, IFNG, IL10, IL1B, IL2, IL4
378.7CCL2, CXCL8, ICAM1, IFNG, IL10, IL1B
388.7CCL3, IFNG, IL10, IL1B, IL2, IL4
398.4CCL2, CCL3, CXCL8, ICAM1, IFNG, IL1B
40
Show member pathways
8.4CCL2, CXCL8, ICAM1, IFNG, IL1B, IL2
418.4CCL2, CXCL8, ICAM1, IFNG, IL1B, IL2
428.4APOL1, HPR, ICAM1, IDO1, IFNG, IL10
43
Show member pathways
8.3CALR, ICAM1, IFNG, IL10, IL1B, IL2
44
Show member pathways
8.3CCL2, CCL3, CXCL8, IL10, IL1B, IL2
458.3CCL2, CCL3, CXCL8, IL10, IL1B, IL2
46
Show member pathways
8.1CCL2, CCL3, CXCL8, IFNG, IL10, IL1B
47
Show member pathways
8.1CALR, CCL2, CCL3, CXCL8, IFNG, IL10
48
Show member pathways
7.9CCL2, CCL3, CXCL8, ICAM1, IFNG, IL10

GO Terms for genes affiliated with Trypanosomiasis

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Cellular components related to Trypanosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.2CALR, ICAM1, IFNG, IL4, IL6, TNF
2blood microparticleGO:00725629.0ALB, APOL1, HP, HPR, TF
3extracellular regionGO:00055766.6ALB, APOL1, CALR, CCL2, CCL3, CXCL8
4extracellular spaceGO:00056156.1ALB, APOL1, CALR, CCL2, CCL3, CXCL8

Biological processes related to Trypanosomiasis according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1neutrophil apoptotic processGO:000178110.9IFNG, IL6
2receptor biosynthetic processGO:003280010.9IL10, TNF
3positive regulation of vitamin D biosynthetic processGO:006055710.8IFNG, TNF
4regulation of isotype switchingGO:004519110.8IL10, IL4
5positive regulation of mononuclear cell migrationGO:007167710.8IL4, TNF
6type 2 immune responseGO:004209210.8IL10, IL4
7sequestering of triglycerideGO:003073010.7IL1B, TNF
8chronic inflammatory response to antigenic stimulusGO:000243910.7IL1B, TNF
9positive regulation of cellular extravasationGO:000269310.7CCL2, ICAM1
10positive regulation of calcidiol 1-monooxygenase activityGO:006055910.6IFNG, IL1B, TNF
11positive regulation of membrane protein ectodomain proteolysisGO:005104410.6IFNG, IL1B, TNF
12negative regulation of growth of symbiont in hostGO:004413010.5IFNG, IL10, TNF
13positive regulation of MHC class II biosynthetic processGO:004534810.5IFNG, IL10, IL4
14positive regulation of isotype switching to IgG isotypesGO:004830410.4IFNG, IL2, IL4
15negative regulation of endothelial cell apoptotic processGO:200035210.4ICAM1, IL10, IL4
16humoral immune responseGO:000695910.4CCL2, IFNG, IL6, TNF
17response to glucocorticoidGO:005138410.4CCL2, IL10, IL6, TNF
18response to amino acidGO:004320010.4CCL2, ICAM1, IL6
19defense response to protozoanGO:004283210.3IFNG, IL10, IL4, IL6
20positive regulation of chemokine biosynthetic processGO:004508010.3IFNG, IL1B, IL4, TNF
21monocyte chemotaxisGO:000254810.3CCL2, CCL3, IL6
22extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.2IL1B, IL2, IL4
23defense response to bacteriumGO:004274210.2HP, IFNG, IL10, TNF
24cellular response to organic substanceGO:007131010.1CALR, ICAM1, IL1B
25positive regulation of phagocytosisGO:005076610.1CALR, IL1B, TNF
26protein kinase B signalingGO:004349110.0CCL2, CCL3, IL1B, TNF
27lipopolysaccharide-mediated signaling pathwayGO:003166310.0CCL2, CCL3, IL1B, TNF
28positive regulation of NF-kappaB transcription factor activityGO:005109210.0ICAM1, IL1B, IL6, TNF
29positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.9IL10, IL1B, IL4, IL6, TNF
30response to organic substanceGO:00100339.9ALB, CALR, IL10, TNF
31cellular response to organic cyclic compoundGO:00714079.8CCL2, CCL3, IL1B, TNF
32positive regulation of apoptotic processGO:00430659.8IDO1, IFNG, IL1B, IL6, TNF
33positive regulation of T cell proliferationGO:00421029.8IFNG, IL1B, IL2, IL4, IL6
34chemotaxisGO:00069359.7CCL2, CCL3, CXCL8, IL4
35positive regulation of nitric oxide biosynthetic processGO:00454299.7ICAM1, IFNG, IL1B, IL6, TNF
36neutrophil chemotaxisGO:00305939.7CCL2, CCL3, CXCL8, IFNG, IL1B
37regulation of cell shapeGO:00083609.7CCL2, CCL3, ICAM1, IL6
38cellular response to interleukin-1GO:00713479.6CCL2, CCL3, CXCL8, ICAM1, IL6
39positive regulation of transcription, DNA-templatedGO:00458939.6IFNG, IL10, IL1B, IL4, IL6, TNF
40cellular response to lipopolysaccharideGO:00712229.6CCL2, CXCL8, ICAM1, IFNG, IL10, IL6
41cellular response to tumor necrosis factorGO:00713569.6CCL2, CCL3, CXCL8, ICAM1, IL6
42response to lipopolysaccharideGO:00324969.6CCL2, ICAM1, IDO1, IL10, IL1B, IL6
43MAPK cascadeGO:00001659.4CCL2, CCL3, IL1B, IL2, TNF
44receptor-mediated endocytosisGO:00068989.3ALB, APOL1, CALR, HP, HPR
45response to ethanolGO:00454719.1CCL2, ICAM1, IL1B, IL2, IL4
46positive regulation of gene expressionGO:00106289.1CALR, CCL3, IFNG, IL1B, IL6, TNF
47inflammatory responseGO:00069549.0CCL2, CCL3, CXCL8, IDO1, IL10, IL1B
48positive regulation of ERK1 and ERK2 cascadeGO:00703748.8CCL2, CCL3, ICAM1, IL1B, IL6, TNF
49positive regulation of cell proliferationGO:00082848.8CALR, IFNG, IL2, IL4, IL6, ODC1
50response to drugGO:00424938.7CALR, CCL2, ICAM1, IFNG, IL10, IL4

Molecular functions related to Trypanosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hemoglobin bindingGO:003049210.5HP, HPR
2growth factor activityGO:00080839.6IL10, IL2, IL4, IL6
3chemokine activityGO:00080099.5CCL2, CCL3, CXCL8
4cytokine activityGO:00051258.5CCL2, IFNG, IL10, IL1B, IL2, IL4

Sources for Trypanosomiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet