MCID: TBR006
MIFTS: 45

Tuberculoid Leprosy malady

Category: Infectious diseases

Aliases & Classifications for Tuberculoid Leprosy

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Aliases & Descriptions for Tuberculoid Leprosy:

Name: Tuberculoid Leprosy 10 12 65
Leprosy, Tuberculoid 36
Leprosy Tuberculoid 47
 
Smooth Leprosy 10
Type T Leprosy 10

Classifications:



External Ids:

Disease Ontology10 DOID:1025
ICD1027 A30.1
SNOMED-CT59 70143003
ICD9CM29 030.1
MeSH36 D015441
UMLS65 C0023351

Summaries for Tuberculoid Leprosy

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Disease Ontology:10 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards based summary: Tuberculoid Leprosy, also known as leprosy, tuberculoid, is related to mycosis fungoides and systemic lupus erythematosus. An important gene associated with Tuberculoid Leprosy is IFNG (Interferon, Gamma), and among its related pathways are African trypanosomiasis and Tuberculosis. Affiliated tissues include skin, bone and lung, and related mouse phenotypes are cellular and hematopoietic system.

Wikipedia:68 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Related Diseases for Tuberculoid Leprosy

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Diseases related to Tuberculoid Leprosy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 243)
idRelated DiseaseScoreTop Affiliating Genes
1mycosis fungoides29.5IFNG, IL10, IL2
2systemic lupus erythematosus29.0CD40LG, IFNG, IL10, IL2
3leprosy11.5
4cycloplegia10.6IFNG, IL10
5dioctophymiasis10.6IFNG, IL10
6opisthorchiasis10.5IFNG, IL10
7buruli ulcer10.5IFNG, IL10
8epidemic pleurodynia10.5IFNG, IL10
9hypercementosis10.5IFNG, IL10
10cow milk allergy10.5IFNG, IL10
11early-onset, autosomal dominant alzheimer disease10.5IFNG, IL10
12rabies10.5CD40LG, CORO1A
13hydronephrosis10.5IFNG, IL10
14cytoplasmic body myopathy10.5IFNG, IL10
15dancing eyes-dancing feet syndrome10.5IFNG, IL10
16hemolytic anemia10.5IFNG, IL10
17beriberi10.5CD40LG, IFNG
18central nervous system melanocytic neoplasm10.5IFNG, IL10
19bacillary angiomatosis10.5CD40LG, IFNG
20peritoneal cystic mesothelioma10.5IFNG, IL10
21oropouche fever10.4CD40LG, IL10
22peripheral retinal degeneration10.4IFNG, IL10
23dysgammaglobulinemia10.4CD40LG, IL10
24dna ligase iv deficiency10.4CD4, CORO1A
25histoplasmosis pericarditis10.4CD40LG, SDHD
26ethmoid sinus squamous cell carcinoma10.4CD4, IFNG
27oral hairy leukoplakia10.4CD40LG, SDHD
28abdominal tuberculosis10.4IFNG, IL10
29chronic hiccups10.4CD4, IFNG
30mature gastric teratoma10.3CD40LG, CD8A
31subacute delirium10.3CD40LG, CD8A
32large intestine lipoma10.3CD40LG, IL10
33cervix melanoma10.3CD40LG, IFNG
34tuberculosis10.3
35prostate transitional cell carcinoma10.3CD4, IL10
36kernicterus due to isoimmunization10.3CD40LG, IL10
37neonatal infective mastitis10.3CD4, IFNG
38oral cavity cancer10.3CD4, CD40LG
39pituitary apoplexy10.3CD4, CD8A
40hyperhomocysteinemia10.3CD4, CD8A
41tracheal stenosis10.2IFNG, IL10
42malignant cornea melanoma10.2CD4, CD8A
43chronic tic disorder10.2CD4, IFNG
44interstitial emphysema10.2CD40LG, IFNG
45acute cystitis10.2CD4, CD8A
46hymenolepiasis10.2CD4, CD40LG
47sacral spinal canal and spinal cord meningioma10.2CD4, CD40LG
48cd3epsilon deficiency10.2CD4, CD8A
49mycotic corneal ulcer10.2CD4, CD8A
50ocular hypotension10.2CD4, CD40LG

Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Symptoms for Tuberculoid Leprosy

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Drugs & Therapeutics for Tuberculoid Leprosy

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Tuberculoid Leprosy


Cochrane evidence based reviews: leprosy, tuberculoid

Genetic Tests for Tuberculoid Leprosy

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Anatomical Context for Tuberculoid Leprosy

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MalaCards organs/tissues related to Tuberculoid Leprosy:

33
Skin, Bone, Lung, Breast, Prostate, Liver, Pituitary

Animal Models for Tuberculoid Leprosy or affiliated genes

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MGI Mouse Phenotypes related to Tuberculoid Leprosy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.1CD4, CD40LG, CORO1A, IFNG, IL10, IL2
2MP:00053976.9CD4, CD40LG, CD8A, CORO1A, IFNG, IL10
3MP:00053796.8CD4, CD40LG, CD8A, CORO1A, IFNG, IL10
4MP:00053876.6CD4, CD40LG, CD8A, CORO1A, IFNG, IL10

Publications for Tuberculoid Leprosy

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Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 235)
idTitleAuthorsYear
1
Borderline tuberculoid leprosy with scrofuloderma: an uncommon association. (25035384)
2014
2
Borderline tuberculoid leprosy and type 1 leprosy reaction in a hepatitis C patient during treatment with interferon and ribavirin. (24346894)
2013
3
Borderline tuberculoid leprosy mimicking mycosis fungoides. (24517048)
2013
4
Images in clinical medicine. Tuberculoid leprosy. (21524216)
2011
5
Post-traumatic inoculation tuberculoid leprosy after injury with a glass bangle. (19743627)
2009
6
Borderline tuberculoid leprosy--an unusual presentation: a case report. (19295116)
2008
7
Greater auricular nerve abscess in borderline tuberculoid leprosy masquerading as jugular vein thrombosis. (17091546)
2006
8
Borderline tuberculoid leprosy in a woman from the state of Georgia with armadillo exposure. (17010758)
2006
9
Borderline tuberculoid leprosy with type 1 reaction in an HIV patient--a phenomenon of immune reconstitution. (16830642)
2005
10
Tuberculoid leprosy confined to glans penis in two cases. (15282972)
2004
11
A case of post-partum borderline tuberculoid leprosy complicated by a median nerve abscess, peptic ulceration and rifampicin-induced haemolytic renal failure. (15282971)
2004
12
Expression of cyclooxygenase type 2 in lepromatous and tuberculoid leprosy lesions. (12752141)
2003
13
Variants of HLA-DR2/DR51 group haplotypes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians. (7602219)
1995
14
An evaluation of the S-100 stain in the histological diagnosis of tuberculoid leprosy and other granulomatous dermatoses. (8046265)
1994
15
Borderline tuberculoid leprosy developing in a pure neuritic case. (1783794)
1991
16
Tuberculoid leprosy--an unusual presentation. (2086689)
1990
17
A case of tuberculoid leprosy in Rhode Island. (2293316)
1990
18
Psoralene in repigmentation of tuberculoid leprosy. (2625362)
1989
19
Suppression of delayed hypersensitivity skin reactions to tuberculin by M. leprae antigens in patients with lepromatous and tuberculoid leprosy. (3308210)
1987
20
Tuberculoid leprosy in Mexicans is associated with HLA-DR3. (3501513)
1987
21
Mycobacterium leprae-reactive T-cell clones isolated from polar lepromatous and tuberculoid leprosy patients. (2830893)
1987
22
Six cases of dapsone-resistant tuberculoid leprosy. (6399070)
1984
23
Clinical electrophysiologic assessment of ulnar nerve transposition in tuberculoid leprosy. (6642835)
1983
24
In vitro lymphocyte stimulation in an approach to study the expression of HLA-encoded genes predisposing to tuberculoid leprosy. (6408015)
1983
25
Regional lymph node involvement in tuberculoid leprosy. (6668925)
1983
26
The pathogenesis and classification of polar tuberculoid leprosy]. (7078339)
1982
27
Pure neural tuberculoid leprosy simulating a peripheral nerve tumor. (7110557)
1982
28
Serum enzyme profile in tuberculoid leprosy. (7098444)
1982
29
Tuberculoid leprosy and HLA in Japanese. (6953616)
1981
30
Borderline tuberculoid leprosy following BCG vaccination. A case report. (7195879)
1981
31
Borderline tuberculoid leprosy with a 'lepromatous' nodule of the nasal mucosa: a case report. (6991811)
1980
32
Some aspects of tuberculoid leprosy and chemotherapeutic trials. (116471)
1979
33
Tuberculoid leprosy and tuberculosis skin: a comparative histopathological study. (895075)
1977
34
Tuberculoid leprosy: a neurologic case report. (4504012)
1972
35
Trial of high dosages of dapsone in the treatment of tuberculoid leprosy. (5150030)
1971
36
Phenoloxidase activity in organisms isolated from lepromatous and tuberculoid leprosy. (16559125)
1970
37
The Kveim test in lepromatous and tuberculoid leprosy. (5394258)
1969
38
Borderline tuberculoid leprosy with neuralgia. (5350424)
1969
39
Tuberculoid leprosy. (5981448)
1966
40
Pure neural tuberculoid leprosy. (4283894)
1965
41
A NEW TECHNIQUE FOR DETECTING MYCOBACTERIUM LEPRAE AND THE PROBLEM OF INFECTIOUSNESS OF TUBERCULOID LEPROSY. (14333144)
1965
42
THE ROLE OF PYRAZON IN REACTIONS IN TUBERCULOID LEPROSY. (14282489)
1964
43
Tuberculoid leprosy in identical twins. (13515394)
1958
44
Primary and secondary tuberculoid leprosy. (13405586)
1956
45
The sulfone treatment of tuberculoid leprosy. (14803132)
1950
46
Transformation of a case of tuberculoid leprosy in reaction to the lepromatous form. (15421705)
1950
47
Tuberculoid leprosy; warty lepride. (18873454)
1948
48
Tuberculoid leprosy. (21065780)
1946
49
Tuberculoid leprosy. (21013478)
1946
50
Demonstration of South African Tuberculoid Leprosy. (19988735)
1932

Variations for Tuberculoid Leprosy

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Expression for genes affiliated with Tuberculoid Leprosy

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Search GEO for disease gene expression data for Tuberculoid Leprosy.

Pathways for genes affiliated with Tuberculoid Leprosy

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Pathways related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
19.8IFNG, IL10
29.4CORO1A, IFNG, IL10
39.4HSPA1A, IFNG, IL10
49.3IFNG, IL2
59.3CD40LG, IFNG, IL10
69.0CD4, CD40LG, IL10
79.0IFNG, IL10, IL2
8
Show member pathways
9.0IFNG, IL10, IL2
9
Show member pathways
9.0IFNG, IL10, IL2
10
Show member pathways
9.0IFNG, IL10, IL2
119.0IFNG, IL10, IL2
12
Show member pathways
8.9CD40LG, HSPA1A, IFNG, IL10
138.8CD40LG, IFNG, IL2
14
Show member pathways
8.8CD40LG, IFNG, IL2
15
Show member pathways
8.8CD8A, IFNG, IL2
168.8CD4, CD40LG, CD8A
178.8CD4, CD40LG, CD8A
188.7CD4, IFNG, IL2
19
Show member pathways
8.3CD4, IFNG, IL10, IL2
208.3CD4, IFNG, IL10, IL2
218.3CD4, IFNG, IL10, IL2
22
Show member pathways
8.3CD4, IFNG, IL10, IL2
23
Show member pathways
8.2CD4, CD8A, IFNG, IL2
247.8CD4, CD8A, IFNG, IL10, IL2
257.8CD4, CD8A, IFNG, IL10, IL2
267.8CD4, CD8A, IFNG, IL10, IL2
27
Show member pathways
7.4CD4, CD40LG, HSPA1A, IFNG, IL10, IL2
28
Show member pathways
7.3CD4, CD40LG, CD8A, IFNG, IL10, IL2
29
Show member pathways
6.9CD4, CD40LG, CD8A, HSPA1A, IFNG, IL10

GO Terms for genes affiliated with Tuberculoid Leprosy

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Biological processes related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1defense response to protozoanGO:004283210.3IFNG, IL10
2negative regulation of growth of symbiont in hostGO:004413010.2IFNG, IL10
3positive regulation of MHC class II biosynthetic processGO:004534810.1IFNG, IL10
4positive regulation of T cell activationGO:00508709.7CD4, CORO1A
5positive regulation of isotype switching to IgG isotypesGO:00483049.7IFNG, IL2
6T cell costimulationGO:00312959.6CD4, CD40LG
7positive regulation of calcium-mediated signalingGO:00508509.5CD4, CD8A
8positive regulation of T cell proliferationGO:00421029.4CORO1A, IFNG, IL2
9T cell activationGO:00421109.3CD4, CD8A
10immune responseGO:00069558.0CD4, IFNG, IL10, IL2

Molecular functions related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.3CD4, CD8A

Sources for Tuberculoid Leprosy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet