MCID: TBR006
MIFTS: 37

Tuberculoid Leprosy malady

Infectious diseases category

Summaries for Tuberculoid Leprosy

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards: Tuberculoid Leprosy, also known as leprosy tuberculoid, is related to sarcoidosis and leprosy. An important gene associated with Tuberculoid Leprosy is HSPA1A (heat shock 70kDa protein 1A), and among its related pathways are Allograft rejection and MAPK signaling pathway. The compounds 8-isoprostane and alpha lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes.

Wikipedia:63 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Aliases & Classifications for Tuberculoid Leprosy

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8Disease Ontology, 60UMLS, 44Novoseek, 27ICD9CM, 56SNOMED-CT, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

tuberculoid leprosy 8 60
leprosy tuberculoid 44
smooth leprosy 8
type t leprosy 8


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Disease Ontology8 DOID:1025
ICD9CM27 030.1
SNOMED-CT56 70143003
MeSH34 D015441
ICD1025 A30.1

Related Diseases for Tuberculoid Leprosy

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Clinical Features for Tuberculoid Leprosy

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Drugs & Therapeutics for Tuberculoid Leprosy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Tuberculoid Leprosy

Drug clinical trials:

Search ClinicalTrials for Tuberculoid Leprosy

Search NIH Clinical Center for Tuberculoid Leprosy

Search CenterWatch for Tuberculoid Leprosy

Genetic Tests for Tuberculoid Leprosy

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Anatomical Context for Tuberculoid Leprosy

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32MalaCards
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MalaCards organs/tissues related to Tuberculoid Leprosy:

32
Skin, T cells, Testes, Bone marrow, Bone, Lymph node, Liver

Animal Models for Tuberculoid Leprosy or affiliated genes

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Publications for Tuberculoid Leprosy

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50PubMed
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Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Borderline tuberculoid evolving across the leprosy spectrum. (23540078)
2013
2
Clinical presentation of tuberculoid leprosy in an epidermodysplasia verruciformis patient. (22711134)
2012
3
Images in clinical medicine. Tuberculoid leprosy. (21524216)
2011
4
Facial tuberculoid leprosy: case report. (20188445)
2011
5
Presence of intestinal helminths decreases T helper type 1 responses in tuberculoid leprosy patients and may increase the risk for multi-bacillary leprosy. (20491787)
2010
6
Total agranulocytosis caused by dapsone therapy for tuberculoid leprosy--an unappreciated serious side effect of anti-leprosy treatment with clinical implications. (20408505)
2009
7
Borderline tuberculoid leprosy--an unusual presentation: a case report. (19295116)
2008
8
Borderline tuberculoid leprosy with type 1 reaction in an HIV patient--a phenomenon of immune reconstitution. (16830642)
2005
9
Expression of transforming growth factor-beta isoforms and their receptors in lepromatous and tuberculoid leprosy. (12641657)
2003
10
Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person. (12491222)
2003
11
Association of a missense mutation of the laminin alpha2 gene with tuberculoid type of leprosy in Indonesian patients. (12100448)
2002
12
Cutaneous granulomas masquerading as tuberculoid leprosy in a patient with congenital combined immunodeficiency. (11514920)
2001
13
Borderline tuberculoid leprosy of the scalp. (11715283)
2001
14
Generalized annular borderline tuberculoid leprosy and update in management of Hansen's disease. (10795079)
2000
15
Primary penile tuberculoid leprosy. (11212485)
2000
16
Polymorphism in heat-shock protein 70-1 (HSP70-1) gene promoter region and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians. (11215307)
2000
17
Borderline tuberculoid leprosy lesion on the scalp presenting with supra orbital neuritis. (9801905)
1998
18
Relapse in a borderline-tuberculoid case of leprosy 5 years after the release from rifampicin monotherapy. (9217356)
1997
19
Cervical canal stenosis masquerading as neuritis in a case of borderline tuberculoid leprosy. (20944366)
1997
20
A case of tuberculoid leprosy with either widespread nerve involvement or a second neurological disease--a case report. (7968188)
1994
21
Minocycline cures tuberculoid leprosy. (1406026)
1992
22
Tuberculoid leprosy in country Victoria. Pitfalls in clinical diagnosis. (1627080)
1992
23
Borderline tuberculoid leprosy developing in a pure neuritic case. (1783794)
1991
24
Tuberculoid leprosy: a case report. (2001631)
1991
25
An attempt to produce experimental tuberculoid leprosy in the nine-banded armadillo. (1783786)
1991
26
A case of tuberculoid leprosy in Rhode Island. (2293316)
1990
27
Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria. (1701000)
1990
28
Cell mediated immunity in tuberculoid leprosy--a study of 'T' lymphocyte population by 'E' rosetty technique. (3494677)
1986
29
Minerals in blood sera and scalp hair in patients with lepromatous leprosy and tuberculoid leprosy. (6577120)
1983
30
An approach to study in vitro the expression of HLA-encoded genetic factors predisposing to tuberculoid leprosy. (6343507)
1983
31
Nerve damage in tuberculoid leprosy. (7132297)
1982
32
Borderline tuberculoid leprosy following BCG vaccination. A case report. (7195879)
1981
33
HLA and sporadic tuberculoid leprosy: a population study in Maharashtra, India. (7336423)
1981
34
Borderline tuberculoid leprosy with a 'lepromatous' nodule of the nasal mucosa: a case report. (6991811)
1980
35
HLA-linked control of susceptibility to tuberculoid leprosy and association with HLA-DR types. (7008255)
1980
36
Mycobacterium leprae in the striated muscle of tuberculoid leprosy patients. (359926)
1978
37
Tuberculoid leprosy: a neurologic case report. (4504012)
1972
38
Fate of Mycobacterium leprae in macrophages of patients with lepromatous or tuberculoid leprosy. (4929374)
1970
39
Follow-up observation on cases with 'reaction' in tuberculoid leprosy. (5401885)
1969
40
Tuberculoid leprosy in state of reaction. (5358133)
1969
41
Solitary neural tuberculoid leprosy. (4298827)
1968
42
Low-resistant tuberculoid leprosy. (5949093)
1966
43
The influence of leprosy on delayed-type skin reactions and serum agglutination titers to Candida albicans. A comparative study of patients with lepromatous and tuberculoid leprosy and controls in Ethiopia. (14016544)
1963
44
Histochemical observations on tuberculoid leprosy. (13947541)
1963
45
Primary and secondary tuberculoid leprosy. (13405586)
1956
46
A case of tuberculoid leprosy. (13293624)
1956
47
Tuberculoid leprosy. (13091392)
1953
48
Tuberculoid leprosy. (21065780)
1946
49
Tuberculoid leprosy. (21013478)
1946
50
Tuberculoid leprosy. (20995204)
1946

Genetic Variations for Tuberculoid Leprosy

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Expression for genes affiliated with Tuberculoid Leprosy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tuberculoid Leprosy

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Pathways for genes affiliated with Tuberculoid Leprosy

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29KEGG, 51QIAGEN, 37NCBI BioSystems Database, 55SinoBiological, 52R&D Systems, 12EMD Millipore, 53Reactome
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Compounds for genes affiliated with Tuberculoid Leprosy

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44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 24HMDB
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Compounds related to Tuberculoid Leprosy according to GeneCards/GeneDecks:

(show all 14)
idCompoundScoreTop Affiliating Genes
18-isoprostane449.4HSPA1A, TNF
2alpha lipoic acid449.4TNF, HSPA1A
3carbamazepine44 49 1111.4TNF, HSPA1A
4manganese superoxide449.4TNF, HSPA1A
515-deoxy-delta-12,14-prostaglandin j2449.4HSPA1A, TNF
6mg 13244 5910.3TNF, HSPA1A
7fmlp449.3HSPA1A, TNF
8n acetylcysteine449.3TNF, HSPA1A
9sb 20358044 5910.2TNF, HSPA1A
10pd 98,059449.2HSPA1A, TNF
11actinomycin d449.1HSPA1A, TNF
12cycloheximide449.1HSPA1A, TNF
13lactate449.0TNF, HSPA1A
14superoxide44 249.8HSPA1A, TNF

GO Terms for genes affiliated with Tuberculoid Leprosy

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Products for genes affiliated with Tuberculoid Leprosy

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  • Antibodies
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Sources for Tuberculoid Leprosy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet