MCID: TBR006
MIFTS: 34

Tuberculoid Leprosy malady

Infectious category

Summaries for Tuberculoid Leprosy

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards: Tuberculoid Leprosy, also known as leprosy tuberculoid, is related to borderline leprosy and lepromatous leprosy. An important gene associated with Tuberculoid Leprosy is HSPA1A (heat shock 70kDa protein 1A), and among its related pathways are Allograft rejection and MAPK signaling pathway. The compounds 8-isoprostane and alpha lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and lymph node.

Wikipedia:64 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Aliases & Classifications for Tuberculoid Leprosy

Sources:
8Disease Ontology, 61UMLS, 45Novoseek, 27ICD9CM, 57SNOMED-CT, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

tuberculoid leprosy 8 61
leprosy tuberculoid 45
smooth leprosy 8
type t leprosy 8


External Ids:

Disease Ontology8 DOID:1025
ICD9CM27 030.1
SNOMED-CT57 70143003
MeSH35 D015441
ICD1025 A30.1

Related Diseases for Tuberculoid Leprosy

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Clinical Features for Tuberculoid Leprosy

Drugs & Therapeutics for Tuberculoid Leprosy

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Tuberculoid Leprosy

Drug clinical trials:

Search ClinicalTrials for Tuberculoid Leprosy

Search NIH Clinical Center for Tuberculoid Leprosy

Search CenterWatch for Tuberculoid Leprosy

Genetic Tests for Tuberculoid Leprosy

Anatomical Context for Tuberculoid Leprosy

Sources:
33MalaCards
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MalaCards organs/tissues related to Tuberculoid Leprosy:

33
Skin, Liver, Lymph node, Bone marrow, Small intestine, T cells

Animal Models for Tuberculoid Leprosy or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Tuberculoid Leprosy

Sources:
51PubMed
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Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 245)
idTitleAuthorsYear
1
Tuberculoid leprosy and cytomegalovirus retinitis as immune restoration disease in a patient with AIDS. (22169463)
2012
2
Trigeminal trophic syndrome complicating a case of borderline tuberculoid leprosy. (22655477)
2012
3
Question: Can you identify this condition? Tuberculoid leprosy. (19155370)
2009
4
Ornamental tattoos and skin lesions. Tattoo inoculation borderline tuberculoid leprosy. (19126044)
2009
5
Borderline tuberculoid leprosy--an unusual presentation: a case report. (19295116)
2008
6
Immune reconstitution inflammatory syndrome or upgrading type 1 reaction? Report of two AIDS patients presenting a shifting from borderline lepromatous leprosy to borderline tuberculoid leprosy. (19274990)
2008
7
Immunohistochemical analysis of the immune cells in the epithelioid cell granuloma of tuberculoid leprosy. (18086607)
2008
8
Penile tuberculoid leprosy in a five year old boy. (16394390)
2005
9
A case of isolated tuberculoid leprosy of antebrachial medial cutaneous nerve. (15549507)
2004
10
Expression of cyclooxygenase type 2 in lepromatous and tuberculoid leprosy lesions. (12752141)
2003
11
Linear cutaneous leishmaniasis occurring on a leg affected by tuberculoid leprosy. (12410723)
2002
12
Comment on "A high incidence of viable Mycobacterium leprae in post-MDT recurrent lesions in tuberculoid leprosy patients" by Shetty et al. (12449896)
2002
13
A sequential study of circulating immune complexes, complement and immunoglobulins in borderline tuberculoid leprosy patients with and without reactions. (9724850)
1998
14
A clinicopathological study of multidrug therapy in borderline tuberculoid leprosy. (7822849)
1994
15
Electro neuro physiological studies in early tuberculoid leprosy. (8345232)
1993
16
Tuberculoid leprosy--an unusual presentation. (2086689)
1990
17
Histological changes in tuberculoid leprosy after fixed duration multidrug therapy for six months. (2220301)
1990
18
Calcification of ulnar nerve in a patient with tuberculoid leprosy--a case report. (2539417)
1989
19
Primary hyperpigmented cutaneous lesions in tuberculoid leprosy. (3204275)
1988
20
Photoactivated topical 8-methoxypsoralen in repigmentation of a tuberculoid leprosy lesion. (3373082)
1988
21
A large hypoanesthetic patch in borderline tuberculoid leprosy. (3221120)
1988
22
Serological responses of patients with lepromatous and tuberculoid leprosy to 30-, 31-, and 32-kilodalton antigens of Mycobacterium tuberculosis. (3141462)
1988
23
Tuberculoid leprosy in Mexicans is associated with HLA-DR3. (3501513)
1987
24
HLA antigens and neural reversal reactions in Ethiopian borderline tuberculoid leprosy patients. (3474306)
1987
25
Demonstration of Mycobacterium leprae antigen in nerves of tuberculoid leprosy. (2441563)
1987
26
Vaccination of borderline tuberculoid leprosy patients with BCG plus killed Mycobacterium leprae. (3316142)
1986
27
Testicular biopsy in antispermatozoal antibody positive tuberculoid leprosy patients. (6539312)
1984
28
Differences in predominant T cell phenotypes and distribution pattern in reactional lesions of tuberculoid and lepromatous leprosy. (6423326)
1984
29
Regional lymph node involvement in tuberculoid leprosy. (6668925)
1983
30
The pathogenesis and classification of polar tuberculoid leprosy]. (7078339)
1982
31
Unique expression of HLA-DR (Ia-like) antigen in the lesions of polar tuberculoid leprosy. (6759822)
1982
32
Borderline tuberculoid leprosy with a 'lepromatous' nodule of the nasal mucosa: a case report. (6991811)
1980
33
Isolated plantar and palmar lesions of tuberculoid leprosy. (543308)
1979
34
Tuberculoid leprosy. (959207)
1976
35
Letter: IgM deposits in tuberculoid leprosy. (773313)
1976
36
Study on the distribution of single initial lesion of tuberculoid leprosy. (1234873)
1975
37
Mechanism of nerve destruction in tuberculoid-borderline leprosy. An electron-microscopic study. (4582968)
1973
38
Phenoloxidase activity in organisms isolated from lepromatous and tuberculoid leprosy. (16559125)
1970
39
The Kveim test in lepromatous and tuberculoid leprosy. (5394258)
1969
40
Hansen's disease: tuberculoid leprosy. (5647037)
1968
41
Clinical observations on 'reaction' in tuberculoid leprosy: preliminary report. (5890063)
1965
42
Undiscussed problems of the bacteriology of tuberculoid and borderline leprosy. (13998167)
1962
43
Tuberculoid leprosy in identical twins. (13515394)
1958
44
Initial dosage of diaminodiphenyl sulfone in the treatment of tuberculoid leprosy. (13562944)
1957
45
Cortisone in the treatment of reactional conditions in tuberculoid leprosy. (13524993)
1957
46
Tuberculoid leprosy; warty lepride. (18873454)
1948
47
Tuberculoid leprosy of lupoid appearance. (20292635)
1947
48
Sarcoidosis; tuberculoid leprosy? late latent syphilis (treated). (21065660)
1945
49
Tuberculoid Leprosy. (19991181)
1937
50
Demonstration of South African Tuberculoid Leprosy. (19988735)
1932

Genetic Variations for Tuberculoid Leprosy

Expression for genes affiliated with Tuberculoid Leprosy

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tuberculoid Leprosy

Search GEO for disease gene expression data for Tuberculoid Leprosy.

Pathways for genes affiliated with Tuberculoid Leprosy

Sources:
30KEGG, 52QIAGEN, 38NCBI BioSystems Database, 56SinoBiological, 53R&D Systems, 12EMD Millipore, 54Reactome
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Compounds for genes affiliated with Tuberculoid Leprosy

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 60Tocris Bioscience, 24HMDB
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Compounds related to Tuberculoid Leprosy according to GeneCards/GeneDecks:

(show all 14)
idCompoundScoreTop Affiliating Genes
18-isoprostane459.4TNF, HSPA1A
2alpha lipoic acid459.4TNF, HSPA1A
3carbamazepine45 50 1111.4TNF, HSPA1A
4manganese superoxide459.4HSPA1A, TNF
515-deoxy-delta-12,14-prostaglandin j2459.4TNF, HSPA1A
6mg 13245 6010.3TNF, HSPA1A
7fmlp459.3TNF, HSPA1A
8n acetylcysteine459.3HSPA1A, TNF
9sb 20358045 6010.2TNF, HSPA1A
10pd 98,059459.2TNF, HSPA1A
11actinomycin d459.1HSPA1A, TNF
12cycloheximide459.1TNF, HSPA1A
13lactate459.0TNF, HSPA1A
14superoxide45 249.8TNF, HSPA1A

GO Terms for genes affiliated with Tuberculoid Leprosy

Products for genes affiliated with Tuberculoid Leprosy

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Sources for Tuberculoid Leprosy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet