MCID: TBR006
MIFTS: 37

Tuberculoid Leprosy malady

Infectious diseases category

Summaries for Tuberculoid Leprosy

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards: Tuberculoid Leprosy, also known as leprosy tuberculoid, is related to sarcoidosis and leprosy. An important gene associated with Tuberculoid Leprosy is HSPA1A (heat shock 70kDa protein 1A), and among its related pathways are Allograft rejection and MAPK signaling pathway. The compounds 8-isoprostane and alpha lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes.

Wikipedia:63 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Aliases & Classifications for Tuberculoid Leprosy

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8Disease Ontology, 60UMLS, 44Novoseek, 27ICD9CM, 56SNOMED-CT, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

tuberculoid leprosy 8 60
leprosy tuberculoid 44
smooth leprosy 8
type t leprosy 8


External Ids:

Disease Ontology8 DOID:1025
ICD9CM27 030.1
SNOMED-CT56 70143003
MeSH34 D015441
ICD1025 A30.1

Related Diseases for Tuberculoid Leprosy

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Clinical Features for Tuberculoid Leprosy

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Drugs & Therapeutics for Tuberculoid Leprosy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Tuberculoid Leprosy

Search CenterWatch for Tuberculoid Leprosy

Genetic Tests for Tuberculoid Leprosy

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Anatomical Context for Tuberculoid Leprosy

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32MalaCards
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MalaCards organs/tissues related to Tuberculoid Leprosy:

32
Skin, T cells, Testes, Bone marrow, Bone, Lymph node, Liver

Animal Models for Tuberculoid Leprosy or affiliated genes

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Publications for Tuberculoid Leprosy

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50PubMed
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Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Trigeminal trophic syndrome complicating a case of borderline tuberculoid leprosy. (22655477)
2012
2
Post-traumatic inoculation tuberculoid leprosy after injury with a glass bangle. (19743627)
2009
3
Ornamental tattoos and skin lesions. Tattoo inoculation borderline tuberculoid leprosy. (19126044)
2009
4
Penile tuberculoid leprosy in a five year old boy. (16394390)
2005
5
Tuberculoid leprosy confined to glans penis in two cases. (15282972)
2004
6
A case of post-partum borderline tuberculoid leprosy complicated by a median nerve abscess, peptic ulceration and rifampicin-induced haemolytic renal failure. (15282971)
2004
7
"Tap sign" in tuberculoid and borderline tuberculoid leprosy. (15485286)
2004
8
Nodular leprosy of childhood and tuberculoid leprosy: a comparative, morphologic, immunopathologic and quantitative study of skin tissue reaction. (14608817)
2003
9
Linear cutaneous leishmaniasis occurring on a leg affected by tuberculoid leprosy. (12410723)
2002
10
Comment on "A high incidence of viable Mycobacterium leprae in post-MDT recurrent lesions in tuberculoid leprosy patients" by Shetty et al. (12449896)
2002
11
Musculoskeletal case of the day. Tuberculoid leprosy. (10470931)
1999
12
Sparing of tuberculoid leprosy patch in a patient with dapsone hypersensitivity syndrome. (9777777)
1998
13
Transporter associated with antigen-processing (TAP) genes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis. (9062973)
1997
14
Reduction of epidermal cell proliferation in skin lesions in lepromatous leprosy is greater than in indeterminate and tuberculoid leprosy lesions. (8627111)
1996
15
Multibacillary nerve histology in clinically diagnosed borderline tuberculoid leprosy patients. (8862266)
1996
16
An evaluation of the S-100 stain in the histological diagnosis of tuberculoid leprosy and other granulomatous dermatoses. (8046265)
1994
17
A clinicopathological study of multidrug therapy in borderline tuberculoid leprosy. (7822849)
1994
18
Histo-bacteriological investigation on borderline tuberculoid leprosy. (1726864)
1991
19
Association of mycobacterial-specific and Mycobacterium leprae specific antibody levels with clinical activity in tuberculoid leprosy: a comparative study of three serological enzyme-immunoassays. (1870374)
1991
20
Therapeutic implications of morphological study of nerves from treated or untreated tuberculoid or lepromatous leprosy. (2030311)
1991
21
Tuberculoid relapse in lepromatous leprosy. (2280657)
1990
22
A case of borderline tuberculoid leprosy presenting with papulonodular lesions. (2401840)
1990
23
Primary involvement of scrotum in tuberculoid leprosy. A case report. (2358693)
1990
24
Histological changes in tuberculoid leprosy after fixed duration multidrug therapy for six months. (2220301)
1990
25
Psoralene in repigmentation of tuberculoid leprosy. (2625362)
1989
26
Destruction of ala nasi and loss of columella in borderline tuberculoid leprosy--a case report. (2703741)
1989
27
Melkersson-Rosenthal syndrome masquerading as tuberculoid leprosy. (3611858)
1987
28
Demonstration of Mycobacterium leprae antigen in nerves of tuberculoid leprosy. (2441563)
1987
29
Vaccination of borderline tuberculoid leprosy patients with BCG plus killed Mycobacterium leprae. (3316142)
1986
30
A case of tuberculoid leprosy--following small pox vaccination. (3843333)
1985
31
Testicular biopsy in antispermatozoal antibody positive tuberculoid leprosy patients. (6539312)
1984
32
Differences in predominant T cell phenotypes and distribution pattern in reactional lesions of tuberculoid and lepromatous leprosy. (6423326)
1984
33
In vitro lymphocyte stimulation in an approach to study the expression of HLA-encoded genes predisposing to tuberculoid leprosy. (6408015)
1983
34
Borderline-tuberculoid leprosy in reaction presenting as photodermatitis: a case report. (7098750)
1982
35
Tuberculoid leprosy and HLA in Japanese. (6953616)
1981
36
Some aspects of tuberculoid leprosy and chemotherapeutic trials. (116471)
1979
37
Post-traumatic tuberculoid leprosy. (A case report). (449281)
1979
38
Tuberculoid leprosy and tuberculosis skin: a comparative histopathological study. (895075)
1977
39
Tuberculoid leprosy. (959207)
1976
40
Letter: IgM deposits in tuberculoid leprosy. (773313)
1976
41
Ocular changes in tuberculoid leprosy. (4637283)
1972
42
Phenoloxidase activity in organisms isolated from lepromatous and tuberculoid leprosy. (16559125)
1970
43
The Kveim test in lepromatous and tuberculoid leprosy. (5394258)
1969
44
Early tuberculoid leprosy. (5915649)
1966
45
Pure neural tuberculoid leprosy. (4283894)
1965
46
Histopathologic lesions of tuberculoid leprosy. Their progressive and regressive changes and clinical significance. (13995061)
1962
47
Visceral tuberculoid leprosy. (14784381)
1950
48
Neural (early tuberculoid?) leprosy. (21013481)
1946
49
Tuberculoid Leprosy. (19991181)
1937
50
Demonstration of South African Tuberculoid Leprosy. (19988735)
1932

Genetic Variations for Tuberculoid Leprosy

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Expression for genes affiliated with Tuberculoid Leprosy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tuberculoid Leprosy

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Pathways for genes affiliated with Tuberculoid Leprosy

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29KEGG, 51QIAGEN, 37NCBI BioSystems Database, 55SinoBiological, 52R&D Systems, 12EMD Millipore, 53Reactome
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Compounds for genes affiliated with Tuberculoid Leprosy

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44Novoseek, 49PharmGKB, 11DrugBank, 59Tocris Bioscience, 24HMDB
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Compounds related to Tuberculoid Leprosy according to GeneCards/GeneDecks:

(show all 14)
idCompoundScoreTop Affiliating Genes
18-isoprostane449.4TNF, HSPA1A
2alpha lipoic acid449.4TNF, HSPA1A
3carbamazepine44 49 1111.4TNF, HSPA1A
4manganese superoxide449.4HSPA1A, TNF
515-deoxy-delta-12,14-prostaglandin j2449.4TNF, HSPA1A
6mg 13244 5910.3TNF, HSPA1A
7fmlp449.3TNF, HSPA1A
8n acetylcysteine449.3HSPA1A, TNF
9sb 20358044 5910.2TNF, HSPA1A
10pd 98,059449.2TNF, HSPA1A
11actinomycin d449.1HSPA1A, TNF
12cycloheximide449.1TNF, HSPA1A
13lactate449.0TNF, HSPA1A
14superoxide44 249.8TNF, HSPA1A

GO Terms for genes affiliated with Tuberculoid Leprosy

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Products for genes affiliated with Tuberculoid Leprosy

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  • Antibodies
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Sources for Tuberculoid Leprosy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet