MCID: TBR006
MIFTS: 43

Tuberculoid Leprosy malady

Category: Infectious diseases

Aliases & Classifications for Tuberculoid Leprosy

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Aliases & Descriptions for Tuberculoid Leprosy:

Name: Tuberculoid Leprosy 10 12 65
Leprosy, Tuberculoid 36
Leprosy Tuberculoid 47
 
Smooth Leprosy 10
Type T Leprosy 10

Classifications:



External Ids:

Disease Ontology10 DOID:1025
ICD1027 A30.1
SNOMED-CT59 70143003
ICD9CM29 030.1
MeSH36 D015441
UMLS65 C0023351

Summaries for Tuberculoid Leprosy

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Disease Ontology:10 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards based summary: Tuberculoid Leprosy, also known as leprosy, tuberculoid, is related to nemaline myopathy and rem sleep behavior disorder. An important gene associated with Tuberculoid Leprosy is IFNG (Interferon, Gamma), and among its related pathways are African trypanosomiasis and Tuberculosis. Affiliated tissues include skin, lung and heart, and related mouse phenotypes are cellular and hematopoietic system.

Wikipedia:68 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Related Diseases for Tuberculoid Leprosy

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Diseases related to Tuberculoid Leprosy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 387)
idRelated DiseaseScoreTop Affiliating Genes
1nemaline myopathy30.4CD4, CD8A
2rem sleep behavior disorder30.3CD4, CD8A
3learning disability30.3CD4, CD40LG
4blastomycosis30.2CD40LG, IFNG, IL10
5food allergy30.1CD4, IFNG, IL10
6inhalation anthrax30.1CD4, CD8A
7variola major29.6CD4, CD40LG, IL2
8rheumatoid arthritis29.6CD40LG, IFNG, IL10, IL2
9peptic ulcer disease29.5CD4, CD40LG, CD8A, SDHD
10leprosy10.8
11cycloplegia10.4IFNG, IL10
12endotheliitis10.4
13dioctophymiasis10.4IFNG, IL10
14opisthorchiasis10.4IFNG, IL10
15buruli ulcer10.4IFNG, IL10
16epidemic pleurodynia10.3IFNG, IL10
17hypercementosis10.3IFNG, IL10
18cow milk allergy10.3IFNG, IL10
19early-onset, autosomal dominant alzheimer disease10.3IFNG, IL10
20rabies10.3CD40LG, CORO1A
21hydronephrosis10.3IFNG, IL10
22cytoplasmic body myopathy10.3IFNG, IL10
23dancing eyes-dancing feet syndrome10.3IFNG, IL10
24hemolytic anemia10.3IFNG, IL10
25beriberi10.3CD40LG, IFNG
26central nervous system melanocytic neoplasm10.3IFNG, IL10
27bacillary angiomatosis10.3CD40LG, IFNG
28lung cancer10.3
29breast cancer10.3
30cerebritis10.3
31pancreatitis10.3
32cardiomyopathy10.3
33peritoneal cystic mesothelioma10.3IFNG, IL10
34oropouche fever10.3CD40LG, IL10
35peripheral retinal degeneration10.3IFNG, IL10
36dysgammaglobulinemia10.3CD40LG, IL10
37dna ligase iv deficiency10.3CD4, CORO1A
38histoplasmosis pericarditis10.3CD40LG, SDHD
39ethmoid sinus squamous cell carcinoma10.2CD4, IFNG
40oral hairy leukoplakia10.2CD40LG, SDHD
41abdominal tuberculosis10.2IFNG, IL10
42chronic hiccups10.2CD4, IFNG
43myocardial infarction10.2
44otitis media10.2
45arthritis10.2
46cerebral palsy10.2
47hepatitis10.2
48leukemia10.2
49colitis10.2
50endocarditis10.2

Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Symptoms for Tuberculoid Leprosy

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Drugs & Therapeutics for Tuberculoid Leprosy

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Tuberculoid Leprosy


Cochrane evidence based reviews: leprosy, tuberculoid

Genetic Tests for Tuberculoid Leprosy

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Anatomical Context for Tuberculoid Leprosy

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MalaCards organs/tissues related to Tuberculoid Leprosy:

33
Skin, Lung, Heart, Bone, Colon, Pituitary, B cells

Animal Models for Tuberculoid Leprosy or affiliated genes

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MGI Mouse Phenotypes related to Tuberculoid Leprosy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.1CD4, CD40LG, CORO1A, IFNG, IL10, IL2
2MP:00053976.9CD4, CD40LG, CD8A, CORO1A, IFNG, IL10
3MP:00053796.8CD4, CD40LG, CD8A, CORO1A, IFNG, IL10
4MP:00053876.6CD4, CD40LG, CD8A, CORO1A, IFNG, IL10

Publications for Tuberculoid Leprosy

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Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 235)
idTitleAuthorsYear
1
Zinc supplementation prolongs the latency of hyperthermia-induced febrile seizures in rats. (27030634)
2016
2
Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility. (26820313)
2016
3
Treatment of Freiberg's disease by Gauthier's dorsal cuneiform osteotomy: Retrospective study of 30A cases. (26362040)
2015
4
Omalizumab in the treatment of allergic bronchopulmonary aspergillosis: One center's experience with 14 cases. (26534756)
2015
5
IL-32I+ down-regulates I^2 integrin (CD18) expression by suppressing PU.1 expression in myeloid cells. (24703937)
2014
6
Spine Bone Texture Assessed by Trabecular Bone Score (TBS) to Evaluate Bone Health in Thalassemia Major. (25348077)
2014
7
Endoilluminator-assisted transcorneal illumination for Descemet membrane endothelial keratoplasty: enhanced intraoperative visualization of the graft in corneal decompensation secondary to pseudophakic bullous keratopathy. (25088633)
2014
8
A new mutation in the gene ROR2 causes brachydactyly type B1. (24954533)
2014
9
Polymorphic pityriasis rosea precipitating psoriasis. (23437430)
2013
10
New developments in the treatment of type 2 diabetes mellitus. (23725247)
2013
11
BH3 mimetic therapy: an emerging and promising approach to treating chronic lymphocytic leukemia. (23339446)
2013
12
Primary spinal germ cell tumors: a case analysis and review of treatment paradigms. (24312128)
2013
13
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. (22395610)
2012
14
Emergency caesarean delivery of a parturient with undiagnosed pemphigoid gestationis. (22626993)
2012
15
Distribution and surfactant association of carcinoembryonic cell adhesion molecule 6 in human lung. (22037359)
2012
16
Behavioral and cognitive impulsivity in obsessive-compulsive disorder and eating disorders. (22749228)
2012
17
The myeloproliferative neoplasms including the eosinophilia-related myeloproliferations associated with tyrosine kinase mutations: changes and issues in classification and diagnosis criteria. (22195408)
2011
18
Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. (20709820)
2011
19
Facial variant of Guillain-BarrAc Syndrome in a patient, days after being vaccinated for influenza A. (21163237)
2011
20
Risk factors influencing chest tube placement among patients with pneumothorax because of CT-guided needle biopsy of the lung. (22008165)
2011
21
Middle cerebral artery occlusion resulting from hypereosinophilic syndrome. (20071179)
2010
22
Oxidative damage in Parkinson disease: Measurement using accurate biomarkers. (19969070)
2010
23
Thiazolidinedione therapy for nonalcoholic steatohepatitis: go, stop, or proceed with caution? (20101743)
2010
24
CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage. (19680552)
2009
25
T cells in sputum of asthmatic patients are activated independently of disease severity or control. (19850398)
2009
26
Tpl-2 kinase downregulates the activity of p53 and enhances signaling pathways leading to activation of activator protein 1 induced by EGF. (19221002)
2009
27
Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients. (19487253)
2009
28
The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma. (18038249)
2008
29
pKa analysis for the zinc-bound water in human carbonic anhydrase II: Benchmark for "multiscale" QM/MM simulations and mechanistic implications. (17506534)
2007
30
Regulation of prostaglandin E synthases: effects of siRNA-mediated inhibition of microsomal prostaglandin E synthase-1. (17707523)
2007
31
Asymptomatic Chlamydia trachomatis-negative non-gonococcal urethritis. (15899091)
2005
32
Effects of GABAergic transmissions on the immunoreactivities of calcium binding proteins in the gerbil hippocampus. (15776449)
2005
33
Major vault protein does not play a role in chemoresistance or drug localization in a non-small cell lung cancer cell line. (15709737)
2005
34
Abnormalities of proinsulin processing in functioning insulinomas: clinical implications. (15473873)
2004
35
Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1. (14660670)
2004
36
Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c. (15059954)
2004
37
Maternal serum cytokine levels in women with hyperemesis gravidarum in the first trimester of pregnancy. (12620429)
2003
38
Location and intensity of IL-8 and TGF-beta2 mRNA production in the fimbrial compartment of fallopian tubes and IL-10 in the endometrium in patients with pyoinflammatory adnexal diseases. (12802400)
2003
39
Alterations in erythrocyte membrane lipid and its fragility in a patient with familial lecithin:cholesterol acyltrasferase (LCAT) deficiency. (12323004)
2002
40
Unusual case presentation of lichen simplex chronicus, Hodgkin's lymphoma, and nonpuerperal hyperprolactinemia-galactorrhea. (11585377)
2001
41
Subclass distribution and the secretory component of serum IgA anti-ganglioside antibodies in Guillain-BarrAc syndrome after Campylobacter jejuni enteritis. (10337924)
1999
42
The role of antioxidant enzymes in the control of opossum gallbladder motility. (10452883)
1999
43
Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro. (9820179)
1998
44
Effects of Ara-C on neutral sphingomyelinase and mitogen- and stress-activated protein kinases in T-lymphocyte cell lines. (8950029)
1996
45
Molecular regulation of heme biosynthesis]. (7616645)
1995
46
Central sleep apnea is associated with increased ventilatory response to carbon dioxide and hypersecretion of growth hormone in patients with acromegaly. (8049836)
1994
47
Enzyme therapy in Gaucher disease type 1: dosage efficacy and adverse effects in 33 patients treated for 6 to 24 months. (8392397)
1993
48
Prevention of experimental coronary thrombosis by hirudin. (2459032)
1988
49
Reconstruction of scrotal and penile skin in elephantiasis. (327094)
1977
50
Nodular lymphoid hyperplasia of the colon associated with dysgammaglobulinemia. (183544)
1976

Variations for Tuberculoid Leprosy

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Expression for genes affiliated with Tuberculoid Leprosy

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Search GEO for disease gene expression data for Tuberculoid Leprosy.

Pathways for genes affiliated with Tuberculoid Leprosy

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Pathways related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
19.8IFNG, IL10
29.4CORO1A, IFNG, IL10
39.4HSPA1A, IFNG, IL10
49.3IFNG, IL2
59.3CD40LG, IFNG, IL10
69.0CD4, CD40LG, IL10
79.0IFNG, IL10, IL2
8
Show member pathways
9.0IFNG, IL10, IL2
9
Show member pathways
9.0IFNG, IL10, IL2
10
Show member pathways
9.0IFNG, IL10, IL2
119.0IFNG, IL10, IL2
12
Show member pathways
8.9CD40LG, HSPA1A, IFNG, IL10
138.8CD40LG, IFNG, IL2
14
Show member pathways
8.8CD40LG, IFNG, IL2
15
Show member pathways
8.8CD8A, IFNG, IL2
168.8CD4, CD40LG, CD8A
178.8CD4, CD40LG, CD8A
188.7CD4, IFNG, IL2
19
Show member pathways
8.3CD4, IFNG, IL10, IL2
208.3CD4, IFNG, IL10, IL2
218.3CD4, IFNG, IL10, IL2
22
Show member pathways
8.3CD4, IFNG, IL10, IL2
23
Show member pathways
8.2CD4, CD8A, IFNG, IL2
247.8CD4, CD8A, IFNG, IL10, IL2
257.8CD4, CD8A, IFNG, IL10, IL2
267.8CD4, CD8A, IFNG, IL10, IL2
27
Show member pathways
7.4CD4, CD40LG, HSPA1A, IFNG, IL10, IL2
28
Show member pathways
7.3CD4, CD40LG, HSPA1A, IFNG, IL10, IL2
29
Show member pathways
6.9CD4, CD40LG, CD8A, HSPA1A, IFNG, IL10

GO Terms for genes affiliated with Tuberculoid Leprosy

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Biological processes related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1defense response to protozoanGO:004283210.3IFNG, IL10
2negative regulation of growth of symbiont in hostGO:004413010.2IFNG, IL10
3positive regulation of MHC class II biosynthetic processGO:004534810.1IFNG, IL10
4positive regulation of T cell activationGO:00508709.7CD4, CORO1A
5positive regulation of isotype switching to IgG isotypesGO:00483049.7IFNG, IL2
6T cell costimulationGO:00312959.6CD4, CD40LG
7positive regulation of calcium-mediated signalingGO:00508509.5CD4, CD8A
8positive regulation of T cell proliferationGO:00421029.4CORO1A, IFNG, IL2
9T cell activationGO:00421109.3CD4, CD8A
10immune responseGO:00069558.0CD4, IFNG, IL10, IL2

Molecular functions related to Tuberculoid Leprosy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.3CD4, CD8A

Sources for Tuberculoid Leprosy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet