MCID: TBR006
MIFTS: 39

Tuberculoid Leprosy malady

Infectious diseases category

Summaries for Tuberculoid Leprosy

About this section
Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Disease Ontology:9 A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center.

MalaCards: Tuberculoid Leprosy, also known as leprosy tuberculoid, is related to leprosy and tuberculosis. An important gene associated with Tuberculoid Leprosy is HSPA1A (heat shock 70kDa protein 1A), and among its related pathways are MAPK signaling pathway and Influenza A. The compounds 8-isoprostane and alpha lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes.

Wikipedia:66 Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically... more...

Aliases & Classifications for Tuberculoid Leprosy

About this section
Sources:
9Disease Ontology, 63UMLS, 46Novoseek, 59SNOMED-CT, 36MeSH, 28ICD9CM, 26ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

tuberculoid leprosy 9 63
leprosy tuberculoid 46
smooth leprosy 9
type t leprosy 9


External Ids:

Disease Ontology9 DOID:1025
MeSH36 D015441
SNOMED-CT59 70143003
ICD9CM28 030.1
ICD1026 A30.1

Related Diseases for Tuberculoid Leprosy

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Tuberculoid Leprosy:



Diseases related to tuberculoid leprosy

Symptoms for Tuberculoid Leprosy

About this section

Drugs & Therapeutics for Tuberculoid Leprosy

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Tuberculoid Leprosy

Drug clinical trials:

Search ClinicalTrials for Tuberculoid Leprosy

Search NIH Clinical Center for Tuberculoid Leprosy

Search CenterWatch for Tuberculoid Leprosy

Genetic Tests for Tuberculoid Leprosy

About this section

Anatomical Context for Tuberculoid Leprosy

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Tuberculoid Leprosy:

34
Skin, T cells, Testes, Liver, Bone, Lymph node, Bone marrow

Animal Models for Tuberculoid Leprosy or affiliated genes

About this section

Publications for Tuberculoid Leprosy

About this section
Sources:
53PubMed
See all sources

Articles related to Tuberculoid Leprosy:

(show top 50)    (show all 221)
idTitleAuthorsYear
1
Borderline tuberculoid leprosy and type 1 leprosy reaction in a hepatitis C patient during treatment with interferon and ribavirin. (24346894)
2013
2
Images in clinical medicine. Tuberculoid leprosy. (21524216)
2011
3
Post-traumatic inoculation tuberculoid leprosy after injury with a glass bangle. (19743627)
2009
4
Borderline tuberculoid leprosy--an unusual presentation: a case report. (19295116)
2008
5
Immune reconstitution inflammatory syndrome or upgrading type 1 reaction? Report of two AIDS patients presenting a shifting from borderline lepromatous leprosy to borderline tuberculoid leprosy. (19274990)
2008
6
Greater auricular nerve abscess in borderline tuberculoid leprosy masquerading as jugular vein thrombosis. (17091546)
2006
7
Borderline tuberculoid leprosy in a woman from the state of Georgia with armadillo exposure. (17010758)
2006
8
Borderline tuberculoid leprosy with type 1 reaction in an HIV patient--a phenomenon of immune reconstitution. (16830642)
2005
9
Tuberculoid leprosy confined to glans penis in two cases. (15282972)
2004
10
A case of post-partum borderline tuberculoid leprosy complicated by a median nerve abscess, peptic ulceration and rifampicin-induced haemolytic renal failure. (15282971)
2004
11
Expression of cyclooxygenase type 2 in lepromatous and tuberculoid leprosy lesions. (12752141)
2003
12
Variants of HLA-DR2/DR51 group haplotypes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians. (7602219)
1995
13
An evaluation of the S-100 stain in the histological diagnosis of tuberculoid leprosy and other granulomatous dermatoses. (8046265)
1994
14
Borderline tuberculoid leprosy developing in a pure neuritic case. (1783794)
1991
15
Tuberculoid leprosy--an unusual presentation. (2086689)
1990
16
A case of tuberculoid leprosy in Rhode Island. (2293316)
1990
17
Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria. (1701000)
1990
18
Psoralene in repigmentation of tuberculoid leprosy. (2625362)
1989
19
Suppression of delayed hypersensitivity skin reactions to tuberculin by M. leprae antigens in patients with lepromatous and tuberculoid leprosy. (3308210)
1987
20
Tuberculoid leprosy in Mexicans is associated with HLA-DR3. (3501513)
1987
21
Mycobacterium leprae-reactive T-cell clones isolated from polar lepromatous and tuberculoid leprosy patients. (2830893)
1987
22
Six cases of dapsone-resistant tuberculoid leprosy. (6399070)
1984
23
Clinical electrophysiologic assessment of ulnar nerve transposition in tuberculoid leprosy. (6642835)
1983
24
In vitro lymphocyte stimulation in an approach to study the expression of HLA-encoded genes predisposing to tuberculoid leprosy. (6408015)
1983
25
Regional lymph node involvement in tuberculoid leprosy. (6668925)
1983
26
The pathogenesis and classification of polar tuberculoid leprosy]. (7078339)
1982
27
Pure neural tuberculoid leprosy simulating a peripheral nerve tumor. (7110557)
1982
28
Serum enzyme profile in tuberculoid leprosy. (7098444)
1982
29
Tuberculoid leprosy and HLA in Japanese. (6953616)
1981
30
Borderline tuberculoid leprosy following BCG vaccination. A case report. (7195879)
1981
31
Borderline tuberculoid leprosy with a 'lepromatous' nodule of the nasal mucosa: a case report. (6991811)
1980
32
Some aspects of tuberculoid leprosy and chemotherapeutic trials. (116471)
1979
33
Tuberculoid leprosy and tuberculosis skin: a comparative histopathological study. (895075)
1977
34
Tuberculoid leprosy: a neurologic case report. (4504012)
1972
35
Trial of high dosages of dapsone in the treatment of tuberculoid leprosy. (5150030)
1971
36
Phenoloxidase activity in organisms isolated from lepromatous and tuberculoid leprosy. (16559125)
1970
37
The Kveim test in lepromatous and tuberculoid leprosy. (5394258)
1969
38
Borderline tuberculoid leprosy with neuralgia. (5350424)
1969
39
Tuberculoid leprosy. (5981448)
1966
40
Pure neural tuberculoid leprosy. (4283894)
1965
41
A NEW TECHNIQUE FOR DETECTING MYCOBACTERIUM LEPRAE AND THE PROBLEM OF INFECTIOUSNESS OF TUBERCULOID LEPROSY. (14333144)
1965
42
THE ROLE OF PYRAZON IN REACTIONS IN TUBERCULOID LEPROSY. (14282489)
1964
43
Tuberculoid leprosy in identical twins. (13515394)
1958
44
Primary and secondary tuberculoid leprosy. (13405586)
1956
45
The sulfone treatment of tuberculoid leprosy. (14803132)
1950
46
Transformation of a case of tuberculoid leprosy in reaction to the lepromatous form. (15421705)
1950
47
Tuberculoid leprosy; warty lepride. (18873454)
1948
48
Tuberculoid leprosy. (21065780)
1946
49
Tuberculoid leprosy. (21013478)
1946
50
Demonstration of South African Tuberculoid Leprosy. (19988735)
1932

Variations for Tuberculoid Leprosy

About this section

Expression for genes affiliated with Tuberculoid Leprosy

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Tuberculoid Leprosy

Search GEO for disease gene expression data for Tuberculoid Leprosy.

Pathways for genes affiliated with Tuberculoid Leprosy

About this section
Sources:
51PathCards, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN, 58SinoBiological, 55R&D Systems, 61Thomson Reuters, 56Reactome
See all sources

Pathways related to Tuberculoid Leprosy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
MAPK signaling pathway39
9.1TNF, HSPA1A
2
Show member pathways
9.1HSPA1A, TNF
3
Show member pathways
9.1TNF, HSPA1A
4
Show member pathways
9.1TNF, HSPA1A
5
Show member pathways
9.1TNF, HSPA1A
69.1HSPA1A, TNF
7
Show member pathways
9.1TNF, HSPA1A
8
Show member pathways
Apoptosis and survival TNFR1 signaling pathway61
TWEAK Signaling Pathway39
Apoptosis Modulation by HSP7039
HIV-1 Nef- Negative effector of Fas and TNF-alpha39
9.1TNF, HSPA1A
9
Show member pathways
9.1HSPA1A, TNF

Compounds for genes affiliated with Tuberculoid Leprosy

About this section
Sources:
46Novoseek, 52PharmGKB, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 25HMDB
See all sources

Compounds related to Tuberculoid Leprosy according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
18-isoprostane469.5HSPA1A, TNF
2alpha lipoic acid469.5TNF, HSPA1A
3carbamazepine46 52 1211.5TNF, HSPA1A
4manganese superoxide469.5HSPA1A, TNF
515-deoxy-delta-12,14-prostaglandin j2469.4TNF, HSPA1A
6mg 13246 6210.4TNF, HSPA1A
7endotoxin469.4HSPA1A, TNF
8fmlp469.4TNF, HSPA1A
9n acetylcysteine469.4HSPA1A, TNF
10sb 20358046 6210.4HSPA1A, TNF
11pd 98,059469.4HSPA1A, TNF
12actinomycin d469.4TNF, HSPA1A
13cyclosporin a46 30 6211.3HSPA1A, TNF
14lactate469.3TNF, HSPA1A
15superoxide46 2510.3TNF, HSPA1A
16cycloheximide469.2TNF, HSPA1A
17h2o2469.2HSPA1A, TNF
18dexamethasone46 52 30 1212.1HSPA1A, TNF
19lipid469.1HSPA1A, TNF
20nitric oxide46 25 1211.0TNF, HSPA1A
21oxygen46 259.8TNF, HSPA1A

GO Terms for genes affiliated with Tuberculoid Leprosy

About this section

Products for genes affiliated with Tuberculoid Leprosy

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Tuberculoid Leprosy

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet