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TB
MCID: TBR010
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Tuberculosis malady |
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10 drugs, 1680 genes, 23 tissues, 841 related diseases, 24 phenotypes, 1946 articles, clinical trials.
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 23MedlinePlus, 2CDC, 44Wikipedia, 33OMIM, 22MalaCards See all sources Export this MalaCard |
MedlinePlus: Tuberculosis (tb) is a bacterial infection caused by a germ called mycobacterium tuberculosis. the bacteria usually attack the lungs, but they can also damage other parts of the body. tb spreads through the air when a person with tb of the lungs or throat coughs, sneezes or talks. if you have been exposed, you should go to your doctor for tests. you are more likely to get tb if you have a weak immune system.
symptoms of tb in the lungs may include
a bad cough that lasts 3 weeks or longer
weight loss
coughing up blood or mucus
weakness or fatigue
fever and chills
night sweats
if not treated properly, tb can be deadly. you can usually cure active tb by taking several medicines for a long period of time. people with latent tb can take medicine so that they do not develop active tb.
centers for disease control and prevention23
MalaCards: Tuberculosis, also known as tuberculous abscess, is related to carcinoma and pneumonia. An important gene associated with Tuberculosis is SLC11A1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1), and among its related pathways are Metabolic pathways and Cytokine-cytokine receptor interaction. The drugs capreomycin and antitubercular drugs and the compounds lipid and dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include lungs, lymph nodes and pericardium, and related mouse phenotypes are homeostasis/metabolism and mortality/aging. Disease Ontology: A primary bacterial infectious disease that is located in lungs, located in lymph nodes, located in pericardium, located in brain, located in pleura or located in gastrointestinal tract, has material basis in mycobacterium tuberculosis, which is transmitted by droplets released into the air when an infected person coughs or sneezes.6 NIH Rare Diseases: Tuberculosis (TB) is a contagious and often severe airborne disease caused by infection with Mycobacterium tuberculosis (Mtb). TB typically affects the lungs, but it also can affect any other organ of the body. It is estimated that more than one-third of the world’s population has Mtb infection; however, only one in ten people infected with TB bacteria develop active TB disease. Early symptoms of active TB can include weight loss, fever, night sweats, and loss of appetite. Symptoms involving areas other than the lungs vary, depending upon the organ or area affected. It is usually treated with a regimen of drugs taken for 6 months to 2 years depending on the type of infection, and can be cured in most people.30 CDC: TB is a disease caused by a bacterium called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can attack any part of the body such as the kidney, spine, and brain. If not treated properly, TB disease can be fatal. TB disease was once the leading cause of death in the United States. Learn More »2 Wikipedia: Tuberculosis, MTB, or TB (short for tubercle bacillus) is a common, and in many cases lethal, infectious...44 more... OMIM: 607948 |
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Sources: 2CDC, 6Disease Ontology, 30NIH Rare Diseases, 8DISEASES, 33OMIM, 32Novoseek , 23MedlinePlus, 43UMLS, 26NCBI Bookshelf, 24MeSH, 40SNOMED-CT See all sources |
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Sources: 33OMIM See all sources |
Clinical features from OMIM: 607948
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for tuberculosis Drug clinical trials:Search ClinicalTrials for tuberculosis Search NIH Clinical Center for tuberculosis Search CenterWatch for tuberculosis Inferred drug relations via UMLS/NDF-RT:43 28 [am500] antituberculars, aminosalicylic acid, antitubercular agents, antitubercular drugs, capreomycin, capreomycin sulfate, cycloserine, ethambutol, ethambutol hydrochloride, ethionamide |
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Sources: 11FMA, 22MalaCards See all sources |
MalaCards organs/tissues related to tuberculosis:22Brain, Bone marrow, Whole blood, Lymph node, Spinal cord, Smooth muscle, Small intestine, Kidney, Liver, Lung, Thyroid, Skin, Ovary, Monocytes, Nk cells, T cells, B cells, Pons, Bronchial epithelium FMA organs/tissues related to tuberculosis:11Lungs, Lymph nodes, Pericardium, Brain, Pleura or
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to tuberculosis:25 (show all 24)
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Sources: 35PubMed See all sources |
Articles related to tuberculosis:(show top 50) (show all 1946)
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 36QIAGEN, 41Thomson Reuters, 10EMD Millipore, 37R&D Systems, 38Reactome See all sources |
Pathways related to tuberculosis according to GeneDecks:(show top 50) (show all 285)
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Sources: 32Novoseek , 42Tocris Bioscience, 34PharmGKB, 9DrugBank, 18HMDB See all sources |
Compounds related to tuberculosis according to GeneDecks:(show top 50) (show all 531)
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Sources: 12Gene Ontology See all sources |
Cellular components related to tuberculosis according to GeneDecks:(show all 20)
Biological processes related to tuberculosis according to GeneDecks:(show top 50) (show all 80)
Molecular functions related to tuberculosis according to GeneDecks:(show all 21)
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