MCID: TBR011
MIFTS: 50

Tuberculous Meningitis malady

Rare diseases, Infectious diseases categories

Summaries for Tuberculous Meningitis

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Wikipedia:63 Tuberculous meningitis is also known as TB meningitis or tubercular meningitis. more...

MalaCards based summary: Tuberculous Meningitis, also known as tuberculosis, meningeal, is related to meningitis and syndrome of inappropriate antidiuretic hormone. An important gene associated with Tuberculous Meningitis is ADA (adenosine deaminase), and among its related pathways are Syndecan-3-mediated signaling events and TRAF Pathway. The compounds bucillamine and imiquimod have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and t cells, and related mouse phenotypes are renal/urinary system and liver/biliary system.

Aliases & Classifications for Tuberculous Meningitis

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Sources:
41NIH Rare Diseases, 43Novoseek, 60UMLS, 25ICD10
See all sources

Tuberculous Meningitis, Aliases & Descriptions:

Name: Tuberculous Meningitis 41
Tuberculosis, Meningeal 60
Meningitis Tuberculous 43
 
Tubercular Meningitis 41
Tb Meningitis 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


External Ids:

ICD1025 A17.0

Related Diseases for Tuberculous Meningitis

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Diseases related to Tuberculous Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 210)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis31.6MBL2, CRP, IL1B, IL8, LYZ, ADA
2syndrome of inappropriate antidiuretic hormone31.0POMC, NPPA
3aseptic meningitis31.0ADA, CCL3
4leishmaniasis30.6IL10, IFNG
5visceral leishmaniasis30.5IFNG, IL10
6encephalitis30.4TLR2, CCL3, IL1B
7vasculitis30.3MBL2, CRP, TNF
8bacterial meningitis30.1TLR2, ADA, CCL3, IL8, IL1B, CRP
9pulmonary tuberculosis30.0TLR2, ADA, CCL3, IFNG, IL10, MBL2
10tuberculosis29.5MBL2, CRP, ALOX5, IL1B, IL10, IFNG
11leukemia29.1TLR2, TNF, ADA, LYZ, CCL3, IFNG
12systemic lupus erythematosus29.0TLR2, TNF, ADA, CCL3, IFNG, IL10
13hydrocephalus10.8
14cerebritis10.7
15miliary tuberculosis10.7
16arachnoiditis10.6
17periapical granuloma10.6CCL3
18leprosy10.6TLR2
19fascioliasis10.6GGT1
20opisthorchiasis10.5GGT1
21gallbladder disease10.5GGT1
22hypoaldosteronism10.5POMC
23melancholia10.5POMC
24coats disease10.5ENO2
25pituitary apoplexy10.5POMC
26filariasis10.5TLR2
27bacteriuria10.5CRP
28adrenal carcinoma10.5POMC
29glutathione synthetase deficiency10.5GGT1
30pericardial effusion10.5ADA
31epidural abscess10.5CRP
32hepatorenal syndrome10.5NPPA
33septic arthritis10.5CRP
34collagen disease10.5CRP
35intervertebral disc disease10.5IL1B
36endophthalmitis10.5VEGFA
37muckle-wells syndrome10.5IL1B
38thyroiditis10.5POMC, MBL2
39craniopharyngioma10.4POMC
40syringomyelia10.4
41neisseria meningitidis infection10.4MBL2, TLR2
42bronchitis10.4CRP
43acute kidney tubular necrosis10.4GGT1, NPPA
44conn's syndrome10.3POMC, NPPA
45bacteremia10.3CRP, MBL2
46pulmonary hypertension10.3ALOX5, NPPA
47hyperaldosteronism10.3POMC, NPPA
48tropical spastic paraparesis10.3CCL3, IFNG
49tuberculoid leprosy10.3IFNG, IL10
50bronchiolitis10.3CCL3, IL8

Graphical network of the top 20 diseases related to Tuberculous Meningitis:



Diseases related to tuberculous meningitis

Symptoms for Tuberculous Meningitis

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Drugs & Therapeutics for Tuberculous Meningitis

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Drug clinical trials:

Search ClinicalTrials for Tuberculous Meningitis

Search NIH Clinical Center for Tuberculous Meningitis

Genetic Tests for Tuberculous Meningitis

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Anatomical Context for Tuberculous Meningitis

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MalaCards organs/tissues related to Tuberculous Meningitis:

31
Testes, Brain, T cells, Spinal cord, Bone, Endothelial, Medulla oblongata, Neutrophil

Animal Models for Tuberculous Meningitis or affiliated genes

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MGI Mouse Phenotypes related to Tuberculous Meningitis:

35 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6TLR2, VEGFA, POMC, ADA, IFNG, MBL2
2MP:00053708.4TLR2, VEGFA, TNF, POMC, ADA, IFNG
3MP:00020068.2TLR2, VEGFA, TNF, POMC, IFNG, IL10
4MP:00053828.0ENO2, IL10, IFNG, TNF, VEGFA
5MP:00053698.0TLR2, VEGFA, TNF, IFNG, IL10, NPPA
6MP:00053798.0TLR2, VEGFA, TNF, POMC, IFNG, IL10
7MP:00107717.9TLR2, VEGFA, TNF, POMC, IFNG, IL10
8MP:00053817.9TLR2, VEGFA, TNF, CCL3, IFNG, IL10
9MP:00053887.8TLR2, VEGFA, TNF, ADA, IFNG, IL10
10MP:00053907.5TLR2, VEGFA, TNF, ADA, IFNG, IL10
11MP:00053857.4TLR2, VEGFA, TNF, POMC, IFNG, IL10
12MP:00053787.1TLR2, VEGFA, TNF, POMC, ADA, CCL3
13MP:00053866.9TLR2, VEGFA, TNF, POMC, CCL3, IFNG
14MP:00107686.8TLR2, VEGFA, TNF, POMC, ADA, CCL3
15MP:00053846.7TLR2, VEGFA, TNF, POMC, ADA, CCL3
16MP:00036316.7TLR2, VEGFA, TNF, POMC, CCL3, IFNG
17MP:00053765.8CCL3, ADA, POMC, TNF, VEGFA, TLR2
18MP:00053975.8NPPA, TLR2, VEGFA, TNF, POMC, ADA
19MP:00053875.7CCL3, ADA, POMC, TNF, VEGFA, TLR2

Publications for Tuberculous Meningitis

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Articles related to Tuberculous Meningitis:

(show top 50)    (show all 568)
idTitleAuthorsYear
1
Definite (microbiologically confirmed) tuberculous meningitis: predictors and prognostic impact. (25724799)
2015
2
Major outcomes of patients with tuberculous meningitis on directly observed thrice a week regime. (25221396)
2014
3
Bacillus Calmette-GuAcrin is a preventive factor in mortality of childhood tuberculous meningitis. (24231588)
2013
4
Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis. (23291048)
2013
5
Role of cerebrospinal fluid adenosine deaminase level estimation in diagnosis of tuberculous meningitis. (24968523)
2013
6
Stroke in a Patient with Tuberculous Meningitis and HIV Infection. (23505605)
2013
7
Applying a consensus case definition to patients with confirmed tuberculous meningitis. (22738790)
2012
8
Fulminant tuberculous meningitis--autopsy case report. (23095273)
2012
9
Diagnostic dilemma in a child with tuberculous meningitis on haloperidol therapy. (21976827)
2011
10
Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis. (21880971)
2011
11
Extrapulmonary tuberculosis: tuberculous meningitis new developments. (21608431)
2011
12
Tuberculous meningitis with positive cell-count in lumbar puncture CSF though negative cell-count from ventricular drainage CSF. (21392525)
2011
13
Impact of bacille Calmette-GuAcrin vaccination on neuroradiological manifestations of pediatric tuberculous meningitis. (19794100)
2010
14
Tuberculous meningitis. (20055767)
2010
15
A study of cytokines in tuberculous meningitis: clinical and MRI correlation. (20691761)
2010
16
Changes in cerebrospinal fluid cytokine expression in tuberculous meningitis patients with treatment. (20407285)
2010
17
Disseminated tuberculosis complicated with tuberculous meningitis, miliary tuberculosis, and thoracal bone fracture while investigating a cervical lymphadenopathy. Tuberculosis: a hidden enemy? (20672504)
2010
18
Shunting in hydrocephalus due to tuberculous meningitis. Cases presenting with high cerebrospinal fluid proteins in pediatric age. (19546843)
2009
19
Surgical outcome of tuberculous meningitis hydrocephalus treated by endoscopic third ventriculostomy: prognostic factors and postoperative neuroimaging for functional assessment of ventriculostomy. (19409015)
2009
20
Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. (19789647)
2009
21
Twenty years of pediatric tuberculous meningitis: a retrospective cohort study in the western cape of South Africa. (19367678)
2009
22
Tuberculous meningitis presenting with unusual clinical features in Nigerians: Two case reports. (18816394)
2008
23
Tuberculous meningitis: does lowering the treatment threshold result in many more treated patients? (18291004)
2008
24
Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults. (18350135)
2008
25
Endoscopic third ventriculostomy in prepontine-suprasellar tuberculoma with tuberculous meningitis hydrocephalus: a case report. (17190988)
2007
26
Tuberculous meningitis in pregnancy presenting as hyperemesis gravidarum. (17437245)
2007
27
Multidrug-resistant tuberculous meningitis in an HIV-positive patient: a challenging disease. (17428182)
2007
28
Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. (17586218)
2007
29
Tuberculous meningitis: neuroimaging features, clinical staging and outcome. (24299940)
2007
30
Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome. (16424233)
2006
31
Ischemic stroke in the setting of tuberculous meningitis. (17032389)
2006
32
Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. (17074278)
2006
33
Neuroimaging features of tuberculous meningitis. (16708732)
2006
34
Syringomyelia: an early complication of tuberculous meningitis. (17034715)
2006
35
Value of early follow-up CT in paediatric tuberculous meningitis. (16079979)
2005
36
Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients. (15939750)
2005
37
Nonaneurysmal subarachnoid hemorrhage secondary to tuberculous meningitis: report of two cases. (14585453)
2003
38
Cerebrospinal fluid lysozyme level for the diagnosis of tuberculous meningitis in children. (12630714)
2003
39
Tuberculous meningitis in adults in Turkey: epidemiology, diagnosis, clinic and laboratory [corrected]. (12803374)
2003
40
Asymptomatic spinal arachnoiditis in patients with tuberculous meningitis. (14504848)
2003
41
Hyponatraemia and hypovolemic shock with tuberculous meningitis. (14719791)
2003
42
The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults. (11792470)
2002
43
Rapid diagnosis of tuberculous meningitis by ligase chain reaction amplification. (11878290)
2002
44
Central fever due to hypothalamic lesion in a patient with tuberculous meningitis. (23978866)
2002
45
Tuberculous meningitis in infancy. (12435563)
2002
46
Prognostic factors in childhood tuberculous meningitis. (12521280)
2002
47
Mannose-binding protein B allele confers protection against tuberculous meningitis. (10203135)
1999
48
C-reactive proteins, immunoglobulin profile and mycobacterial antigens in cerebrospinal fluid of patients with pyogenic and tuberculous meningitis. (1293215)
1992
49
Adenosine deaminase. False negatives in tuberculous meningitis]. (1419094)
1992
50
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984

Variations for Tuberculous Meningitis

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Expression for genes affiliated with Tuberculous Meningitis

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Search GEO for disease gene expression data for Tuberculous Meningitis.

Pathways for genes affiliated with Tuberculous Meningitis

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Pathways related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8IL8, POMC
2
Show member pathways
9.8TNF, TLR2
39.7GGT1, ALOX5
4
Show member pathways
9.5TLR2, IFNG, IL1B
59.5IL8, IFNG, POMC
6
Show member pathways
9.4VEGFA, POMC, CRP
79.4TLR2, TNF, IL1B
89.3TNF, IFNG, IL1B
99.3TNF, IFNG, IL1B
10
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.3IL8, IFNG, TNF
119.3TNF, IFNG, IL8
129.3TNF, IL10, IL1B
139.2TNF, IL8, IL1B
14
Show member pathways
9.2TNF, IL8, IL1B
15
Show member pathways
Immune response IL 12 induced IFN gamma production58
9.2CCL3, IFNG, IL1B
169.1TLR2, TNF, IFNG, IL1B
17
Show member pathways
9.1IL1B, IFNG, TNF, TLR2
189.0IL1B, CCL3, TNF
19
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
9.0IL1B, IL10, IFNG, TNF
20
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.0IL1B, IL10, IFNG, TNF
219.0IL1B, IL10, IFNG, TNF
229.0IL1B, IL10, IFNG, TNF
23
Show member pathways
9.0TNF, IFNG, IL10, IL1B
24
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
9.0TLR2, TNF, IL8, IL1B
259.0IL1B, IL8, TNF, TLR2
268.9TNF, IFNG, IL8, IL1B
27
Show member pathways
Immune response MIF in innate immunity response58
8.9TNF, IFNG, IL8, IL1B
288.9TNF, IL10, IL8, IL1B
29
Show member pathways
8.9TNF, LYZ, IFNG, IL10, NPPA
308.8CCL3, IFNG, IL8, IL1B
31
Show member pathways
8.8IL1B, IL8, IFNG, CCL3
32
Show member pathways
8.8TNF, CCL3, IFNG, IL10
338.7TLR2, TNF, IFNG, IL10, IL1B
34
Show member pathways
IL27-mediated signaling events36
8.7TLR2, TNF, IFNG, IL10, IL1B
35
Show member pathways
8.7TLR2, TNF, IFNG, IL8, IL1B
36
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
8.7TLR2, TNF, IFNG, IL8, IL1B
378.6TNF, IFNG, IL10, IL8, IL1B
388.5NPPA, ENO2, IFNG, VEGFA
39
Show member pathways
8.5TLR2, TNF, IFNG, IL10, IL1B, ALOX5
408.4VEGFA, TNF, IL10, IL8, IL1B
418.3TLR2, TNF, IFNG, IL10, IL8, IL1B
428.3TLR2, TNF, IFNG, IL10, IL8, IL1B
43
Show member pathways
8.3TNF, CCL3, IL10, IL8, IL1B
44
Show member pathways
thioredoxin pathway36
8.3TNF, IFNG, IL1B, ALOX5, CRP, GGT1
45
Show member pathways
8.0TLR2, TNF, CCL3, IL10, IL8, IL1B
46
Show member pathways
8.0TNF, CCL3, IFNG, IL10, IL8, IL1B
47
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
7.7TLR2, TNF, CCL3, IFNG, IL10, IL8
487.5IL1B, TLR2, VEGFA, TNF, CCL3, IFNG
49
Show member pathways
7.2VEGFA, TNF, CCL3, IFNG, IL10, IL8

Compounds for genes affiliated with Tuberculous Meningitis

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Compounds related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 255)
idCompoundScoreTop Affiliating Genes
1bucillamine439.0CRP, VEGFA, IFNG, IL1B
2imiquimod43 59 28 1212.0IL10, IFNG, TLR2, TNF, IL8
3taurine chloramine438.9TNF, IFNG, IL8, IL1B
45 aminosalicylic acid438.9TNF, ALOX5, IL1B, IL8, IL10
5tuberculin438.9IFNG, ADA, MBL2, ENO2, IL10
6rolipram43 59 2810.9TNF, ALOX5, IFNG, ADA, IL10, IL8
7il-12438.9TNF, IL1B, IL8, IFNG, IL10
8budesonide43 49 1210.9TNF, POMC, IFNG, IL8, IL1B
9sulfasalazine28 43 49 1211.8CRP, IL8, IL1B, TNF, ALOX5
10tenidap43 289.8TNF, IL1B, ALOX5, CRP
11fluticasone propionate43 49 59 1211.7IL1B, POMC, IFNG, TNF, IL8
12etanercept43 49 1210.7IL1B, IL8, IL10, IFNG, TNF, CRP
13toxin-1438.6IL8, IL1B, CCL3, TNF, IL10
14mip 1alpha438.6TNF, CCL3, IL8, IL1B, IL10
15ribavirin43 49 1210.6GGT1, MBL2, ADA, IFNG, IL10, CCL3
16polymyxin b438.5IL1B, TLR2, TNF, IFNG, IL8, IL10
17infliximab43 49 1210.5VEGFA, CRP, IL1B, IL10, IFNG, TNF
18groalpha438.5IL8, IL1B, TNF, CCL3, IL10
198-isoprostane438.4TNF, CCL3, IL10, CRP, IL8
20poly(i-c)438.4IL1B, IFNG, CCL3, TNF, TLR2, IL8
21pentoxifylline43 129.4IL10, GGT1, IL1B, IL8, IFNG, TNF
2215-deoxy-delta-12,14-prostaglandin j2438.4IL10, VEGFA, IFNG, IL8, TNF, IL1B
23prednisolone43 28 1210.3CRP, MBL2, POMC, IL10, IFNG, CCL3
24leukotriene b443 59 2410.3IL8, IL1B, CCL3, ALOX5, TNF, TLR2
25prostacyclin438.2ALOX5, CRP, NPPA, IL10, TNF, VEGFA
26lipoteichoic acid438.2TNF, CCL3, IL10, IL8, IL1B, MBL2
27peptidoglycan43 289.2IL10, TLR2, TNF, IL8, IL1B, MBL2
28triptolide438.2TNF, CCL3, IL1B, IL8, VEGFA, IFNG
29polyinosinic-polycytidylic acid438.1IL1B, TLR2, IL8, IL10, IFNG, TNF
30il 10438.1TNF, IL1B, IL10, IL8, CCL3, TLR2
31ccl343 289.1TNF, TLR2, IL1B, IL8, IL10, CCL3
32hydrocortisone43 2 59 1211.1CCL3, IFNG, IL10, IL1B, POMC, TNF
33tacrolimus43 49 1210.0CCL3, IFNG, IL10, ALOX5, GGT1, TNF
34gm-csf43 288.9TNF, CCL3, IFNG, IL10, IL8, IL1B
35rantes437.9IL1B, IL8, IL10, CCL3, TNF, IFNG
36endotoxin437.8IL8, TLR2, TNF, CRP, CCL3, IL1B
37cyclosporin a43 28 599.7IL8, IFNG, ADA, CCL3, NPPA, IL10
38methotrexate49 43 129.7ENO2, IL10, IL1B, CRP, GGT1, TNF
39histamine43 28 249.7TLR2, TNF, ADA, CCL3, IFNG, IL10
40simvastatin43 49 59 28 24 1212.6IFNG, TNF, CCL3, IL10, IL8, CRP
41neopterin437.6MBL2, TNF, ADA, CCL3, IFNG, IL10
42n acetylcysteine437.5GGT1, ALOX5, CRP, IL8, TNF, VEGFA
43aspartate437.3ADA, ALOX5, CCL3, CRP, POMC, GGT1
44indomethacin43 28 59 1210.1CCL3, TNF, POMC, IFNG, IL1B, ALOX5
45sb 20358043 598.1ALOX5, IL1B, IL8, IL10, IFNG, CCL3
46pge2436.8TLR2, NPPA, ALOX5, IL1B, IL8, IL10
47cycloheximide436.8TNF, VEGFA, TLR2, POMC, ALOX5, CRP
48nitric oxide43 24 128.7NPPA, ENO2, MBL2, CCL3, TLR2, IFNG
49dexamethasone43 49 28 128.3ENO2, MBL2, GGT1, ALOX5, IL1B, IL8
50vegf435.2NPPA, POMC, TLR2, VEGFA, ENO2, MBL2

GO Terms for genes affiliated with Tuberculous Meningitis

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Cellular components related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:00301419.3IL1B, POMC, VEGFA
2external side of plasma membraneGO:00098978.9IFNG, ADA, TNF, TLR2
3cell surfaceGO:00099868.7TLR2, VEGFA, TNF, ADA, MBL2
4extracellular regionGO:00055766.5VEGFA, TNF, POMC, LYZ, CCL3, IFNG
5extracellular spaceGO:00056154.9NPPA, VEGFA, TNF, POMC, ADA, LYZ

Biological processes related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1opsonizationGO:000822810.2CRP, MBL2
2negative regulation of interleukin-17 productionGO:003270010.2TLR2, IFNG
3positive regulation of MHC class II biosynthetic processGO:004534810.1IFNG, IL10
4positive regulation of interleukin-18 productionGO:003274110.1TLR2, TNF
5positive regulation of vitamin D biosynthetic processGO:006055710.1IFNG, TNF
6positive regulation of interleukin-6 biosynthetic processGO:004541010.1IFNG, IL1B
7receptor biosynthetic processGO:003280010.1TNF, IL10
8negative regulation of cytokine secretion involved in immune responseGO:000274010.0TNF, IL10
9sequestering of triglycerideGO:003073010.0TNF, IL1B
10positive regulation of heterotypic cell-cell adhesionGO:003411610.0TNF, IL1B
11positive regulation of fever generationGO:003162210.0TNF, IL1B
12negative regulation of lipid storageGO:001088810.0TNF, CRP
13negative regulation of interleukin-12 productionGO:003269510.0IL10, TLR2
14response to molecule of bacterial originGO:000223710.0IL8, IL10
15response to insulinGO:00328689.9NPPA, IL10, TLR2
16leukotriene metabolic processGO:00066919.9GGT1, ALOX5, TLR2
17regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.8IL1B, TNF
18positive regulation of leukocyte migrationGO:00026879.8VEGFA, TLR2
19embryonic digestive tract developmentGO:00485669.8IL8, ADA, TNF
20positive regulation of cytokine secretionGO:00507159.8IL10, TNF, TLR2
21positive regulation of NF-kappaB import into nucleusGO:00423469.8TLR2, TNF, IL1B
22defense response to bacteriumGO:00427429.8MBL2, IL10, IFNG, LYZ
23positive regulation of calcidiol 1-monooxygenase activityGO:00605599.8TNF, IFNG, IL1B
24positive regulation of chemokine biosynthetic processGO:00450809.8TNF, IFNG, IL1B
25positive regulation of membrane protein ectodomain proteolysisGO:00510449.8TNF, IFNG, IL1B
26positive regulation of interleukin-6 productionGO:00327559.8IL1B, TNF, TLR2
27positive regulation of chemokine productionGO:00327229.8TNF, TLR2
28cellular response to lipopolysaccharideGO:00712229.7IL8, IL10, IFNG
29positive regulation of tumor necrosis factor productionGO:00327609.7TLR2, CCL3, IFNG
30cell activationGO:00017759.7TNF, CCL3
31defense response to Gram-positive bacteriumGO:00508309.6TLR2, TNF, CRP, MBL2
32regulation of insulin secretionGO:00507969.6IL1B, IFNG, TNF
33negative regulation of lipid catabolic processGO:00509959.5IL1B, TNF
34positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.5IL1B, IL10, TNF
35positive regulation of nitric oxide biosynthetic processGO:00454299.5TLR2, TNF, IFNG, IL1B
36positive regulation of protein complex assemblyGO:00313349.5VEGFA, TNF
37protein kinase B signalingGO:00434919.4TNF, CCL3, IL1B
38cellular response to organic cyclic compoundGO:00714079.4IL1B, CCL3, TNF
39calcium-mediated signalingGO:00197229.4TNF, CCL3, IL8
40MAPK cascadeGO:00001659.4TNF, CCL3, IL1B
41negative regulation of growth of symbiont in hostGO:00441309.3MBL2, IL10, IFNG, TNF, TLR2
42positive regulation of protein phosphorylationGO:00019349.3VEGFA, TNF, IL1B
43cell-cell signalingGO:00072679.2IL1B, IL10, CCL3, POMC
44neutrophil chemotaxisGO:00305939.2IL1B, IL8, IFNG, CCL3
45lipopolysaccharide-mediated signaling pathwayGO:00316639.2IL1B, CCL3, TNF, TLR2
46positive regulation of NF-kappaB transcription factor activityGO:00510929.1IL1B, TNF, TLR2
47negative regulation of cell proliferationGO:00082859.0TLR2, TNF, IL8, IL1B
48response to hypoxiaGO:00016668.9TLR2, VEGFA, TNF, ADA, CRP, NPPA
49positive regulation of transcription from RNA polymerase II promoterGO:00459448.4IL1B, IL10, IFNG, POMC, TNF, VEGFA
50inflammatory responseGO:00069547.9TLR2, TNF, LYZ, CCL3, IL10, IL8

Molecular functions related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:00420569.3CCL3, VEGFA
2cytokine activityGO:00051258.5IL1B, IL10, IFNG, TNF, VEGFA
3identical protein bindingGO:00428028.4VEGFA, TNF, LYZ, CCL3
4protein bindingGO:00055156.6ADA, TNF, VEGFA, TLR2, CCL3, IL8

Products for genes affiliated with Tuberculous Meningitis

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Sources for Tuberculous Meningitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet