MCID: TBR011
MIFTS: 59

Tuberculous Meningitis malady

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Summaries for Tuberculous Meningitis

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Wikipedia:65 Tuberculous meningitis is also known as TB meningitis or tubercular meningitis. more...

MalaCards based summary: Tuberculous Meningitis, also known as tuberculosis, meningeal, is related to meningitis and syndrome of inappropriate antidiuretic hormone. An important gene associated with Tuberculous Meningitis is ADA (adenosine deaminase), and among its related pathways are Syndecan-3-mediated signaling events and TRAF Pathway. The compounds bucillamine and imiquimod have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and t cells, and related mouse phenotypes are renal/urinary system and liver/biliary system.

Aliases & Classifications for Tuberculous Meningitis

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Sources:
42NIH Rare Diseases, 44Novoseek, 62UMLS, 25ICD10
See all sources

Tuberculous Meningitis, Aliases & Descriptions:

Name: Tuberculous Meningitis 42
Tuberculosis, Meningeal 62
Meningitis Tuberculous 44
 
Tubercular Meningitis 42
Tb Meningitis 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


External Ids:

ICD1025 A17.0

Related Diseases for Tuberculous Meningitis

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Diseases related to Tuberculous Meningitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 214)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis31.6LYZ, MBL2, CRP, IL1B, IL8, ADA
2syndrome of inappropriate antidiuretic hormone31.0NPPA, POMC
3aseptic meningitis31.0ADA, CCL3
4leishmaniasis30.6IFNG, IL10
5visceral leishmaniasis30.5IFNG, IL10
6encephalitis30.4IL1B, CCL3, TLR2
7vasculitis30.3TNF, MBL2, CRP
8hypertension30.2GGT1, POMC, NPPA, CRP
9bacterial meningitis30.1CRP, IL1B, IL8, CCL3, ADA, TLR2
10pulmonary tuberculosis30.0CCL3, MBL2, IL10, IFNG, ADA, TLR2
11sarcoidosis29.6IFNG, TNF, CCL3, IL1B, ADA, LYZ
12tuberculosis29.5IL1B, MBL2, CRP, ALOX5, IL10, IFNG
13leukemia29.1ADA, CCL3, ALOX5, IL1B, IFNG, LYZ
14systemic lupus erythematosus29.0TNF, IL10, MBL2, CRP, ALOX5, IFNG
15hydrocephalus10.8
16cerebritis10.7
17miliary tuberculosis10.7
18arachnoiditis10.6
19periapical granuloma10.6CCL3
20leprosy10.6TLR2
21fascioliasis10.6GGT1
22opisthorchiasis10.5GGT1
23gallbladder disease10.5GGT1
24hypoaldosteronism10.5POMC
25melancholia10.5POMC
26pituitary apoplexy10.5POMC
27coats disease10.5ENO2
28bacteriuria10.5CRP
29filariasis10.5TLR2
30adrenal carcinoma10.5POMC
31pericardial effusion10.5ADA
32glutathione synthetase deficiency10.5GGT1
33epidural abscess10.5CRP
34septic arthritis10.5CRP
35hepatorenal syndrome10.5NPPA
36collagen disease10.5CRP
37degenerative disc disease10.5IL1B
38endophthalmitis10.5VEGFA
39muckle-wells syndrome10.5IL1B
40thyroiditis10.5MBL2, POMC
41craniopharyngioma10.4POMC
42syringomyelia10.4
43neisseria meningitidis infection10.4MBL2, TLR2
44bronchitis10.4CRP
45acute kidney tubular necrosis10.4GGT1, NPPA
46conn's syndrome10.4NPPA, POMC
47bacteremia10.3CRP, MBL2
48hyperaldosteronism10.3POMC, NPPA
49primary pulmonary hypertension10.3NPPA, ALOX5
50tropical spastic paraparesis10.3IFNG, CCL3

Graphical network of the top 20 diseases related to Tuberculous Meningitis:



Diseases related to tuberculous meningitis

Symptoms for Tuberculous Meningitis

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Drugs & Therapeutics for Tuberculous Meningitis

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Drug clinical trials:

Search ClinicalTrials for Tuberculous Meningitis

Search NIH Clinical Center for Tuberculous Meningitis

Genetic Tests for Tuberculous Meningitis

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Anatomical Context for Tuberculous Meningitis

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MalaCards organs/tissues related to Tuberculous Meningitis:

32
Testes, Brain, T cells, Bone, Spinal cord, Endothelial, Medulla oblongata, Neutrophil

Animal Models for Tuberculous Meningitis or affiliated genes

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MGI Mouse Phenotypes related to Tuberculous Meningitis:

36 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6TLR2, VEGFA, POMC, ADA, IFNG, MBL2
2MP:00053708.4TLR2, VEGFA, TNF, POMC, ADA, IFNG
3MP:00020068.2TLR2, VEGFA, TNF, POMC, IFNG, IL10
4MP:00053828.0ENO2, IL10, IFNG, TNF, VEGFA
5MP:00053698.0TLR2, VEGFA, TNF, IFNG, IL10, NPPA
6MP:00053798.0TLR2, VEGFA, TNF, POMC, IFNG, IL10
7MP:00107717.9TLR2, VEGFA, TNF, POMC, IFNG, IL10
8MP:00053817.9TLR2, VEGFA, TNF, CCL3, IFNG, IL10
9MP:00053887.8TLR2, VEGFA, TNF, ADA, IFNG, IL10
10MP:00053907.5TLR2, VEGFA, TNF, ADA, IFNG, IL10
11MP:00053857.4TLR2, VEGFA, TNF, POMC, IFNG, IL10
12MP:00053787.1TLR2, VEGFA, TNF, POMC, ADA, CCL3
13MP:00053866.9TLR2, VEGFA, TNF, POMC, CCL3, IFNG
14MP:00107686.8TLR2, VEGFA, TNF, POMC, ADA, CCL3
15MP:00053846.7TLR2, VEGFA, TNF, POMC, ADA, CCL3
16MP:00036316.7TLR2, VEGFA, TNF, POMC, CCL3, IFNG
17MP:00053765.8CCL3, ADA, POMC, TNF, VEGFA, TLR2
18MP:00053975.8NPPA, TLR2, VEGFA, TNF, POMC, ADA
19MP:00053875.7CCL3, ADA, POMC, TNF, VEGFA, TLR2

Publications for Tuberculous Meningitis

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Articles related to Tuberculous Meningitis:

(show top 50)    (show all 553)
idTitleAuthorsYear
1
Major outcomes of patients with tuberculous meningitis on directly observed thrice a week regime. (25221396)
2014
2
Bacillus Calmette-GuAcrin is a preventive factor in mortality of childhood tuberculous meningitis. (24231588)
2013
3
Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis. (23291048)
2013
4
Role of cerebrospinal fluid adenosine deaminase level estimation in diagnosis of tuberculous meningitis. (24968523)
2013
5
Stroke in a Patient with Tuberculous Meningitis and HIV Infection. (23505605)
2013
6
Applying a consensus case definition to patients with confirmed tuberculous meningitis. (22738790)
2012
7
Fulminant tuberculous meningitis--autopsy case report. (23095273)
2012
8
Diagnostic dilemma in a child with tuberculous meningitis on haloperidol therapy. (21976827)
2011
9
Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis. (21880971)
2011
10
Extrapulmonary tuberculosis: tuberculous meningitis new developments. (21608431)
2011
11
Tuberculous meningitis with positive cell-count in lumbar puncture CSF though negative cell-count from ventricular drainage CSF. (21392525)
2011
12
Impact of bacille Calmette-GuAcrin vaccination on neuroradiological manifestations of pediatric tuberculous meningitis. (19794100)
2010
13
Tuberculous meningitis. (20055767)
2010
14
A study of cytokines in tuberculous meningitis: clinical and MRI correlation. (20691761)
2010
15
Changes in cerebrospinal fluid cytokine expression in tuberculous meningitis patients with treatment. (20407285)
2010
16
Disseminated tuberculosis complicated with tuberculous meningitis, miliary tuberculosis, and thoracal bone fracture while investigating a cervical lymphadenopathy. Tuberculosis: a hidden enemy? (20672504)
2010
17
Tuberculous meningitis presenting as isolated interhemispheric exudates. (20518875)
2010
18
Shunting in hydrocephalus due to tuberculous meningitis. Cases presenting with high cerebrospinal fluid proteins in pediatric age. (19546843)
2009
19
Surgical outcome of tuberculous meningitis hydrocephalus treated by endoscopic third ventriculostomy: prognostic factors and postoperative neuroimaging for functional assessment of ventriculostomy. (19409015)
2009
20
Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. (19789647)
2009
21
Twenty years of pediatric tuberculous meningitis: a retrospective cohort study in the western cape of South Africa. (19367678)
2009
22
Tuberculous meningitis presenting with unusual clinical features in Nigerians: Two case reports. (18816394)
2008
23
Tuberculous meningitis: does lowering the treatment threshold result in many more treated patients? (18291004)
2008
24
Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults. (18350135)
2008
25
Endoscopic third ventriculostomy in prepontine-suprasellar tuberculoma with tuberculous meningitis hydrocephalus: a case report. (17190988)
2007
26
Tuberculous meningitis in pregnancy presenting as hyperemesis gravidarum. (17437245)
2007
27
Multidrug-resistant tuberculous meningitis in an HIV-positive patient: a challenging disease. (17428182)
2007
28
Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. (17586218)
2007
29
Tuberculous meningitis: neuroimaging features, clinical staging and outcome. (24299940)
2007
30
Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome. (16424233)
2006
31
Ischemic stroke in the setting of tuberculous meningitis. (17032389)
2006
32
Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. (17074278)
2006
33
Neuroimaging features of tuberculous meningitis. (16708732)
2006
34
Syringomyelia: an early complication of tuberculous meningitis. (17034715)
2006
35
Value of early follow-up CT in paediatric tuberculous meningitis. (16079979)
2005
36
Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients. (15939750)
2005
37
Nonaneurysmal subarachnoid hemorrhage secondary to tuberculous meningitis: report of two cases. (14585453)
2003
38
Cerebrospinal fluid lysozyme level for the diagnosis of tuberculous meningitis in children. (12630714)
2003
39
Tuberculous meningitis in adults in Turkey: epidemiology, diagnosis, clinic and laboratory [corrected]. (12803374)
2003
40
Asymptomatic spinal arachnoiditis in patients with tuberculous meningitis. (14504848)
2003
41
Hyponatraemia and hypovolemic shock with tuberculous meningitis. (14719791)
2003
42
The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults. (11792470)
2002
43
Rapid diagnosis of tuberculous meningitis by ligase chain reaction amplification. (11878290)
2002
44
Central fever due to hypothalamic lesion in a patient with tuberculous meningitis. (23978866)
2002
45
Tuberculous meningitis in infancy. (12435563)
2002
46
Prognostic factors in childhood tuberculous meningitis. (12521280)
2002
47
Mannose-binding protein B allele confers protection against tuberculous meningitis. (10203135)
1999
48
C-reactive proteins, immunoglobulin profile and mycobacterial antigens in cerebrospinal fluid of patients with pyogenic and tuberculous meningitis. (1293215)
1992
49
Adenosine deaminase. False negatives in tuberculous meningitis]. (1419094)
1992
50
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984

Variations for Tuberculous Meningitis

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Expression for genes affiliated with Tuberculous Meningitis

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Expression patterns in normal tissues for genes affiliated with Tuberculous Meningitis

Search GEO for disease gene expression data for Tuberculous Meningitis.

Pathways for genes affiliated with Tuberculous Meningitis

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Pathways related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8POMC, IL8
2
Show member pathways
9.8TNF, TLR2
39.7ALOX5, GGT1
4
Show member pathways
9.5IL1B, IFNG, TLR2
59.5POMC, IFNG, IL8
69.4IL8, IL1B, TLR2
7
Show member pathways
9.4POMC, CRP, VEGFA
89.4TLR2, TNF, IL1B
99.3IFNG, TNF, IL1B
109.3IL1B, IFNG, TNF
11
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.3IL8, IFNG, TNF
129.3IL8, IFNG, TNF
139.3IL10, IL1B, TNF
14
Show member pathways
9.2IL1B, IL8, TNF
159.2IL1B, TNF, IL8
16
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.2IL1B, IFNG, CCL3
179.1IFNG, TNF, IL1B, TLR2
18
Show member pathways
9.1IL1B, IFNG, TLR2, TNF
199.0IL1B, TNF, CCL3
20
Show member pathways
9.0IL10, IL1B, IFNG, TNF
21
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
9.0TNF, IL10, IFNG, IL1B
22
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
9.0IFNG, TNF, IL10, IL1B
239.0IL1B, TNF, IFNG, IL10
249.0TNF, IFNG, IL10, IL1B
259.0TNF, TLR2, IL1B, IL8
26
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.0TLR2, IL8, IL1B, TNF
278.9TNF, IFNG, IL8, IL1B
28
Show member pathways
Immune response MIF in innate immunity response60
8.9TNF, IL8, IL1B, IFNG
298.9TNF, IL8, IL10, IL1B
30
Show member pathways
8.9NPPA, IL10, IFNG, LYZ, TNF
318.8IL8, IFNG, CCL3, IL1B
32
Show member pathways
8.8CCL3, IFNG, IL8, IL1B
33
Show member pathways
8.8TNF, CCL3, IFNG, IL10
348.7IL10, IL1B, TNF, TLR2, IFNG
35
Show member pathways
IL27-mediated signaling events37
8.7IFNG, IL10, IL1B, TNF, TLR2
36
Show member pathways
8.7IFNG, TNF, TLR2, IL1B, IL8
37
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.7TLR2, TNF, IFNG, IL8, IL1B
388.6IL1B, IL10, TNF, IFNG, IL8
398.5IFNG, VEGFA, ENO2, NPPA
40
Show member pathways
8.5IL1B, IFNG, TNF, TLR2, IL10, ALOX5
418.4IL10, VEGFA, TNF, IL8, IL1B
428.3TLR2, IL1B, IL8, TNF, IFNG, IL10
438.3IFNG, IL8, IL1B, IL10, TLR2, TNF
44
Show member pathways
8.3TNF, CCL3, IL8, IL1B, IL10
45
Show member pathways
thioredoxin pathway37
8.3GGT1, CRP, ALOX5, TNF, IFNG, IL1B
46
Show member pathways
8.0TLR2, IL1B, IL10, TNF, CCL3, IL8
47
Show member pathways
8.0IL8, IFNG, TNF, IL1B, IL10, CCL3
48
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
7.7IL1B, IFNG, CCL3, TNF, TLR2, IL10
497.5IL1B, IFNG, TLR2, IL8, CCL3, TNF
50
Show member pathways
7.2IL1B, ALOX5, IL8, IL10, IFNG, CCL3

Compounds for genes affiliated with Tuberculous Meningitis

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Compounds related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 255)
idCompoundScoreTop Affiliating Genes
1bucillamine449.0CRP, VEGFA, IFNG, IL1B
2imiquimod44 61 28 1112.0IL10, IFNG, TLR2, TNF, IL8
3taurine chloramine448.9TNF, IFNG, IL8, IL1B
45 aminosalicylic acid448.9TNF, ALOX5, IL1B, IL8, IL10
5tuberculin448.9IFNG, ADA, MBL2, ENO2, IL10
6rolipram44 61 2810.9TNF, ALOX5, IFNG, ADA, IL10, IL8
7il-12448.9TNF, IL1B, IL8, IFNG, IL10
8budesonide44 50 1110.9TNF, POMC, IFNG, IL8, IL1B
9sulfasalazine28 44 50 1111.8CRP, IL8, IL1B, TNF, ALOX5
10tenidap44 289.8TNF, IL1B, ALOX5, CRP
11fluticasone propionate44 50 61 1111.7IL1B, POMC, IFNG, TNF, IL8
12etanercept44 50 1110.7IL1B, IL8, IL10, IFNG, TNF, CRP
13toxin-1448.6IL8, IL1B, CCL3, TNF, IL10
14mip 1alpha448.6TNF, CCL3, IL8, IL1B, IL10
15ribavirin44 50 1110.6GGT1, MBL2, ADA, IFNG, IL10, CCL3
16polymyxin b448.5IL1B, TLR2, TNF, IFNG, IL8, IL10
17infliximab44 50 1110.5VEGFA, CRP, IL1B, IL10, IFNG, TNF
18groalpha448.5IL8, IL1B, TNF, CCL3, IL10
198-isoprostane448.4TNF, CCL3, IL10, CRP, IL8
20poly(i-c)448.4IL1B, IFNG, CCL3, TNF, TLR2, IL8
21pentoxifylline44 119.4IL10, GGT1, IL1B, IL8, IFNG, TNF
2215-deoxy-delta-12,14-prostaglandin j2448.4IL10, VEGFA, IFNG, IL8, TNF, IL1B
23prednisolone44 28 1110.3CRP, MBL2, POMC, IL10, IFNG, CCL3
24leukotriene b444 61 2410.3IL8, IL1B, CCL3, ALOX5, TNF, TLR2
25prostacyclin448.2ALOX5, CRP, NPPA, IL10, TNF, VEGFA
26lipoteichoic acid448.2TNF, CCL3, IL10, IL8, IL1B, MBL2
27peptidoglycan44 289.2IL10, TLR2, TNF, IL8, IL1B, MBL2
28triptolide448.2TNF, CCL3, IL1B, IL8, VEGFA, IFNG
29polyinosinic-polycytidylic acid448.1IL1B, TLR2, IL8, IL10, IFNG, TNF
30il 10448.1TNF, IL1B, IL10, IL8, CCL3, TLR2
31ccl344 289.1TNF, TLR2, IL1B, IL8, IL10, CCL3
32hydrocortisone44 2 61 1111.1CCL3, IFNG, IL10, IL1B, POMC, TNF
33tacrolimus44 50 1110.0CCL3, IFNG, IL10, ALOX5, GGT1, TNF
34gm-csf44 288.9TNF, CCL3, IFNG, IL10, IL8, IL1B
35rantes447.9IL1B, IL8, IL10, CCL3, TNF, IFNG
36endotoxin447.8IL8, TLR2, TNF, CRP, CCL3, IL1B
37cyclosporin a44 28 619.7IL8, IFNG, ADA, CCL3, NPPA, IL10
38methotrexate50 44 119.7ENO2, IL10, IL1B, CRP, GGT1, TNF
39histamine44 28 249.7TLR2, TNF, ADA, CCL3, IFNG, IL10
40simvastatin44 50 61 28 24 1112.6IFNG, TNF, CCL3, IL10, IL8, CRP
41neopterin447.6MBL2, TNF, ADA, CCL3, IFNG, IL10
42n acetylcysteine447.5GGT1, ALOX5, CRP, IL8, TNF, VEGFA
43aspartate447.3ADA, ALOX5, CCL3, CRP, POMC, GGT1
44indomethacin44 28 61 1110.1CCL3, TNF, POMC, IFNG, IL1B, ALOX5
45sb 20358044 618.1ALOX5, IL1B, IL8, IL10, IFNG, CCL3
46pge2446.8TLR2, NPPA, ALOX5, IL1B, IL8, IL10
47cycloheximide446.8TNF, VEGFA, TLR2, POMC, ALOX5, CRP
48nitric oxide44 24 118.7NPPA, ENO2, MBL2, CCL3, TLR2, IFNG
49dexamethasone44 50 28 118.3ENO2, MBL2, GGT1, ALOX5, IL1B, IL8
50vegf445.2NPPA, POMC, TLR2, VEGFA, ENO2, MBL2

GO Terms for genes affiliated with Tuberculous Meningitis

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Cellular components related to Tuberculous Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301419.3IL1B, POMC, VEGFA
2external side of plasma membraneGO:0098978.9IFNG, ADA, TNF, TLR2
3cell surfaceGO:0099868.7TLR2, VEGFA, TNF, ADA, MBL2
4extracellular regionGO:0055766.5VEGFA, TNF, POMC, LYZ, CCL3, IFNG
5extracellular spaceGO:0056154.9NPPA, VEGFA, TNF, POMC, ADA, LYZ

Biological processes related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1opsonizationGO:00822810.2MBL2, CRP
2negative regulation of interleukin-17 productionGO:03270010.2TLR2, IFNG
3positive regulation of MHC class II biosynthetic processGO:04534810.2IL10, IFNG
4positive regulation of interleukin-18 productionGO:03274110.1TNF, TLR2
5positive regulation of vitamin D biosynthetic processGO:06055710.1TNF, IFNG
6positive regulation of interleukin-6 biosynthetic processGO:04541010.1IFNG, IL1B
7receptor biosynthetic processGO:03280010.1TNF, IL10
8negative regulation of cytokine secretion involved in immune responseGO:00274010.0IL10, TNF
9sequestering of triglycerideGO:03073010.0IL1B, TNF
10negative regulation of interleukin-12 productionGO:03269510.0TLR2, IL10
11negative regulation of lipid storageGO:01088810.0TNF, CRP
12positive regulation of heterotypic cell-cell adhesionGO:03411610.0IL1B, TNF
13positive regulation of fever generationGO:03162210.0TNF, IL1B
14response to molecule of bacterial originGO:00223710.0IL8, IL10
15response to insulinGO:0328689.9NPPA, IL10, TLR2
16leukotriene metabolic processGO:0066919.9ALOX5, GGT1, TLR2
17regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.8IL1B, TNF
18embryonic digestive tract developmentGO:0485669.8TNF, ADA, IL8
19positive regulation of cytokine secretionGO:0507159.8IL10, TNF, TLR2
20positive regulation of leukocyte migrationGO:0026879.8TLR2, VEGFA
21positive regulation of NF-kappaB import into nucleusGO:0423469.8TLR2, IL1B, TNF
22defense response to bacteriumGO:0427429.8MBL2, IL10, IFNG, LYZ
23positive regulation of calcidiol 1-monooxygenase activityGO:0605599.8TNF, IL1B, IFNG
24positive regulation of chemokine biosynthetic processGO:0450809.8TNF, IFNG, IL1B
25positive regulation of membrane protein ectodomain proteolysisGO:0510449.8IFNG, IL1B, TNF
26positive regulation of interleukin-6 productionGO:0327559.8TNF, IL1B, TLR2
27positive regulation of chemokine productionGO:0327229.8TLR2, TNF
28cellular response to lipopolysaccharideGO:0712229.7IL10, IFNG, IL8
29cell activationGO:0017759.7CCL3, TNF
30positive regulation of tumor necrosis factor productionGO:0327609.7TLR2, CCL3, IFNG
31defense response to Gram-positive bacteriumGO:0508309.6CRP, MBL2, TLR2, TNF
32regulation of insulin secretionGO:0507969.6TNF, IFNG, IL1B
33negative regulation of lipid catabolic processGO:0509959.5IL1B, TNF
34positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.5IL10, TNF, IL1B
35positive regulation of nitric oxide biosynthetic processGO:0454299.5IFNG, IL1B, TLR2, TNF
36positive regulation of protein complex assemblyGO:0313349.5VEGFA, TNF
37protein kinase B signalingGO:0434919.4IL1B, CCL3, TNF
38cellular response to organic cyclic compoundGO:0714079.4IL1B, TNF, CCL3
39calcium-mediated signalingGO:0197229.4IL8, CCL3, TNF
40MAPK cascadeGO:0001659.4IL1B, TNF, CCL3
41negative regulation of growth of symbiont in hostGO:0441309.3IL10, MBL2, TNF, TLR2, IFNG
42positive regulation of protein phosphorylationGO:0019349.3VEGFA, IL1B, TNF
43cell-cell signalingGO:0072679.2IL1B, IL10, POMC, CCL3
44neutrophil chemotaxisGO:0305939.2IL1B, IL8, IFNG, CCL3
45lipopolysaccharide-mediated signaling pathwayGO:0316639.2IL1B, TNF, TLR2, CCL3
46positive regulation of NF-kappaB transcription factor activityGO:0510929.1TLR2, IL1B, TNF
47negative regulation of cell proliferationGO:0082859.0TNF, TLR2, IL1B, IL8
48response to hypoxiaGO:0016668.9TNF, NPPA, CRP, ADA, VEGFA, TLR2
49positive regulation of transcription from RNA polymerase II promoterGO:0459448.4IL1B, TLR2, POMC, VEGFA, TNF, IFNG
50inflammatory responseGO:0069547.9LYZ, IL8, TLR2, CCL3, IL10, CRP

Molecular functions related to Tuberculous Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:0420569.3CCL3, VEGFA
2cytokine activityGO:0051258.5IL1B, IL10, IFNG, TNF, VEGFA
3identical protein bindingGO:0428028.4VEGFA, TNF, LYZ, CCL3
4protein bindingGO:0055156.6ADA, TNF, VEGFA, TLR2, CCL3, IL8

Products for genes affiliated with Tuberculous Meningitis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Tuberculous Meningitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet