MCID: TBR011
MIFTS: 58

Tuberculous Meningitis malady

Rare diseases, Infectious diseases categories
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Summaries for Tuberculous Meningitis

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65Wikipedia, 33MalaCards
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Wikipedia:65 Tuberculous meningitis is also known as TB meningitis or tubercular meningitis. more...

MalaCards: Tuberculous Meningitis, also known as tuberculosis, meningeal, is related to meningitis and tuberculosis. An important gene associated with Tuberculous Meningitis is ADA (adenosine deaminase), and among its related pathways are Syndecan-3-mediated signaling events and TRAF Pathway. The compounds bucillamine and imiquimod have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and t cells, and related mouse phenotypes are renal/urinary system and liver/biliary system.

Aliases & Classifications for Tuberculous Meningitis

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43NIH Rare Diseases, 45Novoseek, 62UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Aliases & Descriptions:

tuberculous meningitis 43
tuberculosis, meningeal 62
meningitis tuberculous 45
tubercular meningitis 43
tb meningitis 43


External Ids:

ICD1025 A17.0

Related Diseases for Tuberculous Meningitis

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17GeneCards, 18GeneDecks
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Diseases related to Tuberculous Meningitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 210)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis32.0LYZ, MBL2, CRP, IL1B, IL8, ADA
2tuberculosis30.9IL1B, MBL2, CRP, ALOX5, IL10, IFNG
3syndrome of inappropriate antidiuretic hormone30.6NPPA, POMC
4aseptic meningitis30.5ADA, CCL3
5bacterial meningitis30.4CRP, IL1B, IL8, CCL3, ADA, TLR2
6vasculitis30.3TNF, MBL2, CRP
7leishmaniasis30.2IFNG, IL10
8visceral leishmaniasis30.2IFNG, IL10
9encephalitis30.2IL1B, CCL3, TLR2
10hypertension30.1GGT1, POMC, NPPA, CRP
11pulmonary tuberculosis30.0CCL3, MBL2, IL10, IFNG, ADA, TLR2
12sarcoidosis30.0IFNG, TNF, CCL3, IL1B, ADA, LYZ
13leukemia29.8ADA, CCL3, ALOX5, IL1B, IFNG, LYZ
14systemic lupus erythematosus29.8TNF, IL10, MBL2, CRP, ALOX5, IFNG
15hydrocephalus10.8
16miliary tuberculosis10.7
17cerebritis10.7
18arachnoiditis10.6
19syringomyelia10.4
20internuclear ophthalmoplegia10.2
21cervicitis10.2
22cranial nerve palsy10.2
23ophthalmoplegia10.2
24arachnoid cysts10.2
25hiv-110.2
26endotheliitis10.2
27periapical granuloma10.1CCL3
28leprosy10.1TLR2
29fascioliasis10.1GGT1
30opisthorchiasis10.1GGT1
31gallbladder disease10.1GGT1
32hypoaldosteronism10.1POMC
33melancholia10.1POMC
34pituitary apoplexy10.1POMC
35coats disease10.1ENO2
36bacteriuria10.1CRP
37filariasis10.1TLR2
38adrenal carcinoma10.1POMC
39pericardial effusion10.1ADA
40glutathione synthetase deficiency10.1GGT1
41epidural abscess10.1CRP
42septic arthritis10.1CRP
43hepatorenal syndrome10.1NPPA
44collagen disease10.1CRP
45degenerative disc disease10.1IL1B
46endophthalmitis10.1VEGFA
47muckle-wells syndrome10.1IL1B
48thyroiditis10.1MBL2, POMC
49craniopharyngioma10.1POMC
50neisseria meningitidis infection10.1MBL2, TLR2

Graphical network of the top 20 diseases related to Tuberculous Meningitis:



Diseases related to tuberculous meningitis

Symptoms for Tuberculous Meningitis

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Drugs & Therapeutics for Tuberculous Meningitis

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Tuberculous Meningitis

Search NIH Clinical Center for Tuberculous Meningitis

Genetic Tests for Tuberculous Meningitis

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Anatomical Context for Tuberculous Meningitis

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33MalaCards
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MalaCards organs/tissues related to Tuberculous Meningitis:

33
Testes, Brain, T cells, Bone, Spinal cord, Endothelial, Medulla oblongata

Animal Models for Tuberculous Meningitis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Tuberculous Meningitis:

37 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6TLR2, VEGFA, POMC, ADA, IFNG, MBL2
2MP:00053708.4TLR2, VEGFA, TNF, POMC, ADA, IFNG
3MP:00020068.2TLR2, VEGFA, TNF, POMC, IFNG, IL10
4MP:00053828.0ENO2, IL10, IFNG, TNF, VEGFA
5MP:00053698.0TLR2, VEGFA, TNF, IFNG, IL10, NPPA
6MP:00053798.0TLR2, VEGFA, TNF, POMC, IFNG, IL10
7MP:00107717.9TLR2, VEGFA, TNF, POMC, IFNG, IL10
8MP:00053817.9TLR2, VEGFA, TNF, CCL3, IFNG, IL10
9MP:00053887.8TLR2, VEGFA, TNF, ADA, IFNG, IL10
10MP:00053907.5TLR2, VEGFA, TNF, ADA, IFNG, IL10
11MP:00053857.4TLR2, VEGFA, TNF, POMC, IFNG, IL10
12MP:00053787.1TLR2, VEGFA, TNF, POMC, ADA, CCL3
13MP:00053866.9TLR2, VEGFA, TNF, POMC, CCL3, IFNG
14MP:00107686.8TLR2, VEGFA, TNF, POMC, ADA, CCL3
15MP:00053846.7TLR2, VEGFA, TNF, POMC, ADA, CCL3
16MP:00036316.7TLR2, VEGFA, TNF, POMC, CCL3, IFNG
17MP:00053765.8CCL3, ADA, POMC, TNF, VEGFA, TLR2
18MP:00053975.8NPPA, TLR2, VEGFA, TNF, POMC, ADA
19MP:00053875.7CCL3, ADA, POMC, TNF, VEGFA, TLR2

Publications for Tuberculous Meningitis

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52PubMed
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Articles related to Tuberculous Meningitis:

(show top 50)    (show all 533)
idTitleAuthorsYear
1
Bacillus Calmette-GuAcrin is a preventive factor in mortality of childhood tuberculous meningitis. (24231588)
2013
2
Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis. (23291048)
2013
3
Stroke in a Patient with Tuberculous Meningitis and HIV Infection. (23505605)
2013
4
Stages of tuberculous meningitis: a clinicoradiologic analysis. (23763800)
2013
5
Applying a consensus case definition to patients with confirmed tuberculous meningitis. (22738790)
2012
6
Fulminant tuberculous meningitis--autopsy case report. (23095273)
2012
7
Validation of diagnostic algorithm to differentiate between tuberculous meningitis and acute bacterial meningitis. (22244850)
2012
8
Diagnostic dilemma in a child with tuberculous meningitis on haloperidol therapy. (21976827)
2011
9
Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis. (21880971)
2011
10
Extrapulmonary tuberculosis: tuberculous meningitis new developments. (21608431)
2011
11
Tuberculous meningitis with positive cell-count in lumbar puncture CSF though negative cell-count from ventricular drainage CSF. (21392525)
2011
12
Impact of bacille Calmette-GuAcrin vaccination on neuroradiological manifestations of pediatric tuberculous meningitis. (19794100)
2010
13
Tuberculous meningitis. (20055767)
2010
14
A study of cytokines in tuberculous meningitis: clinical and MRI correlation. (20691761)
2010
15
Changes in cerebrospinal fluid cytokine expression in tuberculous meningitis patients with treatment. (20407285)
2010
16
Disseminated tuberculosis complicated with tuberculous meningitis, miliary tuberculosis, and thoracal bone fracture while investigating a cervical lymphadenopathy. Tuberculosis: a hidden enemy? (20672504)
2010
17
Tuberculous meningitis presenting as isolated interhemispheric exudates. (20518875)
2010
18
Shunting in hydrocephalus due to tuberculous meningitis. Cases presenting with high cerebrospinal fluid proteins in pediatric age. (19546843)
2009
19
Surgical outcome of tuberculous meningitis hydrocephalus treated by endoscopic third ventriculostomy: prognostic factors and postoperative neuroimaging for functional assessment of ventriculostomy. (19409015)
2009
20
Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. (19789647)
2009
21
Twenty years of pediatric tuberculous meningitis: a retrospective cohort study in the western cape of South Africa. (19367678)
2009
22
Tuberculous meningitis presenting with unusual clinical features in Nigerians: Two case reports. (18816394)
2008
23
Tuberculous meningitis: does lowering the treatment threshold result in many more treated patients? (18291004)
2008
24
Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults. (18350135)
2008
25
Endoscopic third ventriculostomy in prepontine-suprasellar tuberculoma with tuberculous meningitis hydrocephalus: a case report. (17190988)
2007
26
Tuberculous meningitis in pregnancy presenting as hyperemesis gravidarum. (17437245)
2007
27
Multidrug-resistant tuberculous meningitis in an HIV-positive patient: a challenging disease. (17428182)
2007
28
Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. (17586218)
2007
29
Tuberculous meningitis: neuroimaging features, clinical staging and outcome. (24299940)
2007
30
Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome. (16424233)
2006
31
Ischemic stroke in the setting of tuberculous meningitis. (17032389)
2006
32
Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. (17074278)
2006
33
Neuroimaging features of tuberculous meningitis. (16708732)
2006
34
Syringomyelia: an early complication of tuberculous meningitis. (17034715)
2006
35
Value of early follow-up CT in paediatric tuberculous meningitis. (16079979)
2005
36
Demonstration of components of antigen 85 complex in cerebrospinal fluid of tuberculous meningitis patients. (15939750)
2005
37
Nonaneurysmal subarachnoid hemorrhage secondary to tuberculous meningitis: report of two cases. (14585453)
2003
38
Cerebrospinal fluid lysozyme level for the diagnosis of tuberculous meningitis in children. (12630714)
2003
39
Tuberculous meningitis in adults in Turkey: epidemiology, diagnosis, clinic and laboratory [corrected]. (12803374)
2003
40
Asymptomatic spinal arachnoiditis in patients with tuberculous meningitis. (14504848)
2003
41
Hyponatraemia and hypovolemic shock with tuberculous meningitis. (14719791)
2003
42
The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults. (11792470)
2002
43
Rapid diagnosis of tuberculous meningitis by ligase chain reaction amplification. (11878290)
2002
44
Central fever due to hypothalamic lesion in a patient with tuberculous meningitis. (23978866)
2002
45
Tuberculous meningitis in infancy. (12435563)
2002
46
Prognostic factors in childhood tuberculous meningitis. (12521280)
2002
47
Mannose-binding protein B allele confers protection against tuberculous meningitis. (10203135)
1999
48
C-reactive proteins, immunoglobulin profile and mycobacterial antigens in cerebrospinal fluid of patients with pyogenic and tuberculous meningitis. (1293215)
1992
49
Adenosine deaminase. False negatives in tuberculous meningitis]. (1419094)
1992
50
Internuclear ophthalmoplegia in tuberculous meningitis. A report of two cases. (6468455)
1984

Variations for Tuberculous Meningitis

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Expression for genes affiliated with Tuberculous Meningitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tuberculous Meningitis

Search GEO for disease gene expression data for Tuberculous Meningitis.

Pathways for genes affiliated with Tuberculous Meningitis

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Sources:
50PathCards, 38NCBI BioSystems Database, 53QIAGEN, 51PharmGKB, 54R&D Systems, 12EMD Millipore, 60Thomson Reuters, 55Reactome, 5Cell Signaling Technology, 30KEGG
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Pathways related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8IL8, POMC
2
Show member pathways
9.8TNF, TLR2
39.7GGT1, ALOX5
4
Show member pathways
9.5TLR2, IFNG, IL1B
59.5IL8, IFNG, POMC
69.4IL1B, IL8, TLR2
7
Show member pathways
9.4VEGFA, POMC, CRP
89.4TLR2, TNF, IL1B
99.3TNF, IFNG, IL1B
109.3TNF, IFNG, IL1B
11
Show member pathways
Calcium signaling in the CD4+ TCR pathway38
9.3IL8, IFNG, TNF
129.3TNF, IFNG, IL8
139.3TNF, IL10, IL1B
149.2TNF, IL8, IL1B
15
Show member pathways
9.2TNF, IL8, IL1B
16
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.2CCL3, IFNG, IL1B
179.1TLR2, TNF, IFNG, IL1B
18
Show member pathways
9.1IL1B, IFNG, TNF, TLR2
199.0IL1B, CCL3, TNF
20
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
9.0IL1B, IL10, IFNG, TNF
21
Show member pathways
IL23-mediated signaling events38
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling38
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
9.0IL1B, IL10, IFNG, TNF
229.0IL1B, IL10, IFNG, TNF
239.0IL1B, IL10, IFNG, TNF
24
Show member pathways
9.0TNF, IFNG, IL10, IL1B
25
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.0TLR2, TNF, IL8, IL1B
269.0IL1B, IL8, TNF, TLR2
278.9TNF, IFNG, IL8, IL1B
28
Show member pathways
Immune response MIF in innate immunity response60
8.9TNF, IFNG, IL8, IL1B
298.9TNF, IL10, IL8, IL1B
30
Show member pathways
8.9TNF, LYZ, IFNG, IL10, NPPA
318.8CCL3, IFNG, IL8, IL1B
32
Show member pathways
8.8IL1B, IL8, IFNG, CCL3
33
Show member pathways
8.8TNF, CCL3, IFNG, IL10
348.7TLR2, TNF, IFNG, IL10, IL1B
35
Show member pathways
IL27-mediated signaling events38
8.7TLR2, TNF, IFNG, IL10, IL1B
36
Show member pathways
8.7TLR2, TNF, IFNG, IL8, IL1B
37
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.7TLR2, TNF, IFNG, IL8, IL1B
388.6TNF, IFNG, IL10, IL8, IL1B
398.5NPPA, ENO2, IFNG, VEGFA
40
Show member pathways
8.5TLR2, TNF, IFNG, IL10, IL1B, ALOX5
418.4VEGFA, TNF, IL10, IL8, IL1B
428.3TLR2, TNF, IFNG, IL10, IL8, IL1B
438.3TLR2, TNF, IFNG, IL10, IL8, IL1B
44
Show member pathways
8.3TNF, CCL3, IL10, IL8, IL1B
45
Show member pathways
thioredoxin pathway38
8.3TNF, IFNG, IL1B, ALOX5, CRP, GGT1
46
Show member pathways
8.0TLR2, TNF, CCL3, IL10, IL8, IL1B
47
Show member pathways
8.0TNF, CCL3, IFNG, IL10, IL8, IL1B
48
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
7.7TLR2, TNF, CCL3, IFNG, IL10, IL8
497.5IL1B, TLR2, VEGFA, TNF, CCL3, IFNG
50
Show member pathways
7.2VEGFA, TNF, CCL3, IFNG, IL10, IL8

Compounds for genes affiliated with Tuberculous Meningitis

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Sources:
45Novoseek, 61Tocris Bioscience, 29IUPHAR, 11DrugBank, 51PharmGKB, 24HMDB, 3BitterDB
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Compounds related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 255)
idCompoundScoreTop Affiliating Genes
1bucillamine459.0CRP, VEGFA, IFNG, IL1B
2imiquimod45 61 29 1112.0IL10, IFNG, TLR2, TNF, IL8
3taurine chloramine458.9TNF, IFNG, IL8, IL1B
45 aminosalicylic acid458.9TNF, ALOX5, IL1B, IL8, IL10
5tuberculin458.9IFNG, ADA, MBL2, ENO2, IL10
6rolipram45 61 2910.9TNF, ALOX5, IFNG, ADA, IL10, IL8
7il-12458.9TNF, IL1B, IL8, IFNG, IL10
8budesonide45 51 1110.9TNF, POMC, IFNG, IL8, IL1B
9sulfasalazine29 45 51 1111.8CRP, IL8, IL1B, TNF, ALOX5
10tenidap45 299.8TNF, IL1B, ALOX5, CRP
11fluticasone propionate45 51 61 1111.7IL1B, POMC, IFNG, TNF, IL8
12etanercept45 51 1110.7IL1B, IL8, IL10, IFNG, TNF, CRP
13toxin-1458.6IL8, IL1B, CCL3, TNF, IL10
14mip 1alpha458.6TNF, CCL3, IL8, IL1B, IL10
15ribavirin45 51 1110.6GGT1, MBL2, ADA, IFNG, IL10, CCL3
16polymyxin b458.5IL1B, TLR2, TNF, IFNG, IL8, IL10
17infliximab45 51 1110.5VEGFA, CRP, IL1B, IL10, IFNG, TNF
18groalpha458.5IL8, IL1B, TNF, CCL3, IL10
198-isoprostane458.4TNF, CCL3, IL10, CRP, IL8
20poly(i-c)458.4IL1B, IFNG, CCL3, TNF, TLR2, IL8
21pentoxifylline45 119.4IL10, GGT1, IL1B, IL8, IFNG, TNF
2215-deoxy-delta-12,14-prostaglandin j2458.4IL10, VEGFA, IFNG, IL8, TNF, IL1B
23prednisolone45 29 1110.3CRP, MBL2, POMC, IL10, IFNG, CCL3
24leukotriene b445 61 2410.3IL8, IL1B, CCL3, ALOX5, TNF, TLR2
25prostacyclin458.2ALOX5, CRP, NPPA, IL10, TNF, VEGFA
26lipoteichoic acid458.2TNF, CCL3, IL10, IL8, IL1B, MBL2
27peptidoglycan45 299.2IL10, TLR2, TNF, IL8, IL1B, MBL2
28triptolide458.2TNF, CCL3, IL1B, IL8, VEGFA, IFNG
29polyinosinic-polycytidylic acid458.1IL1B, TLR2, IL8, IL10, IFNG, TNF
30il 10458.1TNF, IL1B, IL10, IL8, CCL3, TLR2
31ccl345 299.1TNF, TLR2, IL1B, IL8, IL10, CCL3
32hydrocortisone45 3 61 1111.1CCL3, IFNG, IL10, IL1B, POMC, TNF
33tacrolimus45 51 1110.0CCL3, IFNG, IL10, ALOX5, GGT1, TNF
34gm-csf45 298.9TNF, CCL3, IFNG, IL10, IL8, IL1B
35rantes457.9IL1B, IL8, IL10, CCL3, TNF, IFNG
36endotoxin457.8IL8, TLR2, TNF, CRP, CCL3, IL1B
37cyclosporin a45 29 619.7IL8, IFNG, ADA, CCL3, NPPA, IL10
38methotrexate51 45 119.7ENO2, IL10, IL1B, CRP, GGT1, TNF
39histamine45 29 249.7TLR2, TNF, ADA, CCL3, IFNG, IL10
40simvastatin45 51 61 29 24 1112.6IFNG, TNF, CCL3, IL10, IL8, CRP
41neopterin457.6MBL2, TNF, ADA, CCL3, IFNG, IL10
42n acetylcysteine457.5GGT1, ALOX5, CRP, IL8, TNF, VEGFA
43aspartate457.3ADA, ALOX5, CCL3, CRP, POMC, GGT1
44indomethacin45 29 61 1110.1CCL3, TNF, POMC, IFNG, IL1B, ALOX5
45sb 20358045 618.1ALOX5, IL1B, IL8, IL10, IFNG, CCL3
46pge2456.8TLR2, NPPA, ALOX5, IL1B, IL8, IL10
47cycloheximide456.8TNF, VEGFA, TLR2, POMC, ALOX5, CRP
48nitric oxide45 24 118.7NPPA, ENO2, MBL2, CCL3, TLR2, IFNG
49dexamethasone45 51 29 118.3ENO2, MBL2, GGT1, ALOX5, IL1B, IL8
50vegf455.2NPPA, POMC, TLR2, VEGFA, ENO2, MBL2

GO Terms for genes affiliated with Tuberculous Meningitis

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Sources:
16Gene Ontology
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Cellular components related to Tuberculous Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301419.3IL1B, POMC, VEGFA
2external side of plasma membraneGO:0098978.9IFNG, ADA, TNF, TLR2
3cell surfaceGO:0099868.7TLR2, VEGFA, TNF, ADA, MBL2
4extracellular regionGO:0055766.5VEGFA, TNF, POMC, LYZ, CCL3, IFNG
5extracellular spaceGO:0056154.9NPPA, VEGFA, TNF, POMC, ADA, LYZ

Biological processes related to Tuberculous Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1opsonizationGO:00822810.2CRP, MBL2
2negative regulation of interleukin-17 productionGO:03270010.2TLR2, IFNG
3positive regulation of MHC class II biosynthetic processGO:04534810.1IFNG, IL10
4positive regulation of interleukin-18 productionGO:03274110.1TLR2, TNF
5positive regulation of vitamin D biosynthetic processGO:06055710.1IFNG, TNF
6positive regulation of interleukin-6 biosynthetic processGO:04541010.1IFNG, IL1B
7receptor biosynthetic processGO:03280010.1TNF, IL10
8negative regulation of cytokine secretion involved in immune responseGO:00274010.0TNF, IL10
9sequestering of triglycerideGO:03073010.0TNF, IL1B
10positive regulation of heterotypic cell-cell adhesionGO:03411610.0TNF, IL1B
11positive regulation of fever generationGO:03162210.0TNF, IL1B
12negative regulation of lipid storageGO:01088810.0TNF, CRP
13negative regulation of interleukin-12 productionGO:03269510.0IL10, TLR2
14response to molecule of bacterial originGO:00223710.0IL8, IL10
15response to insulinGO:0328689.9NPPA, IL10, TLR2
16leukotriene metabolic processGO:0066919.9GGT1, ALOX5, TLR2
17regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.8IL1B, TNF
18positive regulation of leukocyte migrationGO:0026879.8VEGFA, TLR2
19embryonic digestive tract developmentGO:0485669.8IL8, ADA, TNF
20positive regulation of cytokine secretionGO:0507159.8IL10, TNF, TLR2
21positive regulation of NF-kappaB import into nucleusGO:0423469.8TLR2, TNF, IL1B
22defense response to bacteriumGO:0427429.8MBL2, IL10, IFNG, LYZ
23positive regulation of calcidiol 1-monooxygenase activityGO:0605599.8TNF, IFNG, IL1B
24positive regulation of chemokine biosynthetic processGO:0450809.8TNF, IFNG, IL1B
25positive regulation of membrane protein ectodomain proteolysisGO:0510449.8TNF, IFNG, IL1B
26positive regulation of interleukin-6 productionGO:0327559.8IL1B, TNF, TLR2
27cellular response to lipopolysaccharideGO:0712229.7IL8, IL10, IFNG
28positive regulation of tumor necrosis factor productionGO:0327609.7TLR2, CCL3, IFNG
29cell activationGO:0017759.7TNF, CCL3
30defense response to Gram-positive bacteriumGO:0508309.6TLR2, TNF, CRP, MBL2
31regulation of insulin secretionGO:0507969.6IL1B, IFNG, TNF
32negative regulation of lipid catabolic processGO:0509959.5IL1B, TNF
33induction of positive chemotaxisGO:0509309.5IL8, VEGFA
34positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.5IL1B, IL10, TNF
35positive regulation of nitric oxide biosynthetic processGO:0454299.5TLR2, TNF, IFNG, IL1B
36positive regulation of protein complex assemblyGO:0313349.5VEGFA, TNF
37protein kinase B signalingGO:0434919.4TNF, CCL3, IL1B
38cellular response to organic cyclic compoundGO:0714079.4IL1B, CCL3, TNF
39calcium-mediated signalingGO:0197229.4TNF, CCL3, IL8
40MAPK cascadeGO:0001659.4TNF, CCL3, IL1B
41negative regulation of growth of symbiont in hostGO:0441309.3MBL2, IL10, IFNG, TNF, TLR2
42positive regulation of protein phosphorylationGO:0019349.3VEGFA, TNF, IL1B
43cell-cell signalingGO:0072679.2IL1B, IL10, CCL3, POMC
44neutrophil chemotaxisGO:0305939.2IL1B, IL8, IFNG, CCL3
45lipopolysaccharide-mediated signaling pathwayGO:0316639.2IL1B, CCL3, TNF, TLR2
46positive regulation of NF-kappaB transcription factor activityGO:0510929.1IL1B, TNF, TLR2
47negative regulation of cell proliferationGO:0082859.0TLR2, TNF, IL8, IL1B
48response to hypoxiaGO:0016668.9TLR2, VEGFA, TNF, ADA, CRP, NPPA
49positive regulation of transcription from RNA polymerase II promoterGO:0459448.4IL1B, IL10, IFNG, POMC, TNF, VEGFA
50inflammatory responseGO:0069547.9TLR2, TNF, LYZ, CCL3, IL10, IL8

Molecular functions related to Tuberculous Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:0420569.3CCL3, VEGFA
2cytokine activityGO:0051258.5IL1B, IL10, IFNG, TNF, VEGFA
3identical protein bindingGO:0428028.4VEGFA, TNF, LYZ, CCL3
4protein bindingGO:0055156.6ADA, TNF, VEGFA, TLR2, CCL3, IL8

Products for genes affiliated with Tuberculous Meningitis

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Sources for Tuberculous Meningitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet