MCID: TBR011
MIFTS: 47

Tuberculous Meningitis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Tuberculous Meningitis

Aliases & Descriptions for Tuberculous Meningitis:

Name: Tuberculous Meningitis 50
Tuberculosis, Meningeal 69
Meningitis Tuberculous 52
Tubercular Meningitis 50
Tb Meningitis 50

Classifications:



External Ids:

ICD10 33 A17.0

Summaries for Tuberculous Meningitis

MalaCards based summary : Tuberculous Meningitis, also known as tuberculosis, meningeal, is related to choroiditis and pulmonary tuberculosis. An important gene associated with Tuberculous Meningitis is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Toll-like Receptor Signaling Pathway. The drugs Dexamethasone and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include testes, t cells and brain, and related phenotypes are hematopoietic system and immune system

Wikipedia : 71 Tuberculous meningitis is also known as TB meningitis or tubercular meningitis. Tuberculous meningitis... more...

Related Diseases for Tuberculous Meningitis

Diseases related to Tuberculous Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
id Related Disease Score Top Affiliating Genes
1 choroiditis 29.5 CCL2 CXCL8 TNF
2 pulmonary tuberculosis 29.5 CCL3 CXCL8 TNF
3 meningitis 11.0
4 tuberculosis 10.4
5 hydrocephalus 10.3
6 myeloid proliferations related to down syndrome 10.3 CXCL8 TLR2
7 conidiobolomycosis 10.2 CXCL8 TNF
8 cerebritis 10.2
9 appendicitis 10.2 ENO2 LYZ
10 thymic neuroendocrine carcinoma 10.2 CXCL8 TNF
11 myoclonic astatic epilepsy 10.2 CXCL8 TLR2
12 urticaria 10.2 ADA ALOX5 TNF
13 handl syndrome 10.2 CXCL8 TLR2 TNF
14 mycoplasmal pneumonia 10.2 CXCL8 TLR2 TNF
15 pyelonephritis 10.2 CXCL8 NPPA TNF
16 inappropriate adh syndrome 10.2 CXCL8 TLR2 TNF
17 ovarian cystic teratoma 10.2 CXCL8 TLR2 TNF
18 cutaneous candidiasis 10.2 CCL2 CXCL8
19 degenerative disc disease 10.2 TNF VEGFA
20 miliary tuberculosis 10.2
21 unilateral hypoactive labyrinth 10.2 CXCL8 TLR2 TNF
22 fasciitis 10.2 CXCL8 TLR2 TNF
23 asbestosis 10.2 CXCL8 TLR2 TNF
24 spontaneous ocular nystagmus 10.2 ALOX5 CXCL8 TNF
25 foodborne botulism 10.2 ADA TLR2 TNF
26 keratomalacia 10.2 CXCL8 TLR2 TNF
27 lymphatic system disease 10.2 ENO2 VEGFA
28 nephropathy with pretibial epidermolysis bullosa and deafness 10.1 CXCL8 TLR2 TNF
29 renal adenoma 10.1 LYZ TNF VEGFA
30 villonodular synovitis 10.1 ADA ENO2
31 urinary bladder posterior wall cancer 10.1 ADA NPPA VEGFA
32 mixed mineral dust pneumoconiosis 10.1 ADA CCL2 CXCL8
33 spondylolysis 10.1 CXCL8 TNF VEGFA
34 uveitis 10.1 CCL2 LYZ TNF
35 skin conditions 10.1 CCL2 CXCL8 TNF
36 leukoplakia of vagina 10.1 TLR2 TNF VEGFA
37 anterior foramen magnum meningioma 10.1 ADA CCL3 TNF
38 hyperimmunoglobulin syndrome 10.1 CCL2 CXCL8 TNF
39 infancy electroclinical syndrome 10.1 CCL2 CXCL8 TNF
40 baritosis 10.1 CCL2 CXCL8 TNF
41 amelogenesis imperfecta 10.1 CCL2 CXCL8 TNF
42 japanese spotted fever 10.1 CCL2 CXCL8
43 histiocytosis 10.1 CXCL8 TLR2 TNF
44 oral cavity carcinoma in situ 10.1 ADA CCL2 TLR2
45 neovascular glaucoma 10.1 CCL2 CXCL8 TNF
46 arachnoiditis 10.1
47 central nervous system leiomyosarcoma 10.1 ENO2 LYZ VEGFA
48 bone angioendothelial sarcoma 10.1 CCL2 CXCL8 TNF
49 paranasal sinus sarcoma 10.1 CXCL8 GGT1 TNF
50 acute gonococcal cystitis 10.1 CXCL8 VEGFA

Graphical network of the top 20 diseases related to Tuberculous Meningitis:



Diseases related to Tuberculous Meningitis

Symptoms & Phenotypes for Tuberculous Meningitis

MGI Mouse Phenotypes related to Tuberculous Meningitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.92 NPPA TLR2 TNF ADA VEGFA ALOX5
2 immune system MP:0005387 9.86 TLR2 TNF ADA VEGFA ALOX5 CCL2
3 renal/urinary system MP:0005367 9.63 NPPA TLR2 ADA VEGFA GGT1 LYZ
4 respiratory system MP:0005388 9.43 TLR2 TNF ADA VEGFA ENO2 LYZ
5 skeleton MP:0005390 9.17 TLR2 TNF ADA VEGFA ALOX5 GGT1

Drugs & Therapeutics for Tuberculous Meningitis

Drugs for Tuberculous Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 85)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
2 Vaccines Phase 4,Phase 2,Phase 1
3 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
4 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
5 Dexamethasone acetate Phase 4,Phase 2,Phase 3 1177-87-3
6 glucocorticoids Phase 4,Phase 2,Phase 3
7
protease inhibitors Phase 4,Phase 2,Phase 3
8 Adjuvants, Immunologic Phase 4,Phase 2
9 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
10 HIV Protease Inhibitors Phase 4,Phase 2,Phase 3
11 Hormone Antagonists Phase 4,Phase 2,Phase 3
12 Dexamethasone 21-phosphate Phase 4,Phase 2,Phase 3
13 Hormones Phase 4,Phase 2,Phase 3
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3
15 Antiemetics Phase 4,Phase 2,Phase 3
16 BB 1101 Phase 4,Phase 2,Phase 3
17 Autonomic Agents Phase 4,Phase 2,Phase 3
18 BCG Vaccine Phase 4,Phase 2
19 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3
20 Heptavalent Pneumococcal Conjugate Vaccine Phase 4
21
Efavirenz Approved, Investigational Phase 2, Phase 3 154598-52-4 64139
22
Lamivudine Approved, Investigational Phase 2, Phase 3 134678-17-4 60825
23
Meloxicam Approved, Vet_approved Phase 3 71125-38-7 5281106 54677470
24
Rifampin Approved Phase 2, Phase 3, Phase 1 13292-46-1 5458213 5381226
25
Nevirapine Approved Phase 2, Phase 3 129618-40-2 4463
26
Stavudine Approved, Investigational Phase 2, Phase 3 3056-17-5 18283
27
Isoniazid Approved Phase 2, Phase 3,Phase 1 54-85-3 3767
28
Pyrazinamide Approved Phase 2, Phase 3,Phase 1 98-96-4 1046
29
Streptomycin Approved, Vet_approved Phase 2, Phase 3 57-92-1 19649
30
Ethambutol Approved Phase 2, Phase 3, Phase 1 74-55-5 3279 14052
31
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 65-23-6 1054
32
Pyridoxal Approved, Nutraceutical Phase 2, Phase 3 66-72-8 1050
33
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
34 Analgesics Phase 3,Phase 2
35 Cyclooxygenase 2 Inhibitors Phase 3
36 Cyclooxygenase Inhibitors Phase 3,Phase 2
37 Cytochrome P-450 CYP2C9 Inhibitors Phase 2, Phase 3
38 Cytochrome P-450 CYP3A Inducers Phase 2, Phase 3, Phase 1
39 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3,Phase 1
40 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3, Phase 1
41 Analgesics, Non-Narcotic Phase 3,Phase 2
42 Anti-HIV Agents Phase 2, Phase 3
43 Anti-Infective Agents Phase 2, Phase 3, Phase 1
44 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 2
45 Anti-Retroviral Agents Phase 2, Phase 3
46 Reverse Transcriptase Inhibitors Phase 2, Phase 3
47 Antirheumatic Agents Phase 3,Phase 2
48 Antiviral Agents Phase 2, Phase 3
49 Trace Elements Phase 2, Phase 3
50 Vitamin B 6 Phase 2, Phase 3

Interventional clinical trials:

(show all 21)
id Name Status NCT ID Phase
1 Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults Unknown status NCT01811823 Phase 4
2 A Study of the Interaction Between BCG And MenC Immunisation: BAM Active, not recruiting NCT02002156 Phase 4
3 The Relationships Between Gene Polymorphisms of LTA4H and Dexamethasone Treatment for Tuberculous Meningitis Not yet recruiting NCT02588196 Phase 4
4 TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial Unknown status NCT02060006 Phase 3
5 High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study Completed NCT02169882 Phase 2, Phase 3
6 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3
7 Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Completed NCT01589289 Phase 3
8 Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO) Completed NCT00495326 Phase 2, Phase 3
9 Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial) Not yet recruiting NCT03092817 Phase 3
10 Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis Not yet recruiting NCT03100786 Phase 3
11 A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis Completed NCT02237365 Phase 2
12 Rifampicin Explorative PK Study for Tuberculous Meningitis Comparing Oral and Intravenous Preparation Completed NCT01802502 Phase 2
13 Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study Completed NCT01158755 Phase 2
14 Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination Completed NCT01650389 Phase 2
15 Optimizing Treatment to Improve TBM Outcomes in Children Recruiting NCT02958709 Phase 1, Phase 2
16 Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa Active, not recruiting NCT02391415 Phase 2
17 Study of the Safety and Immunogenicity of Bacille Calmette Guerin (BCG) Vaccine Completed NCT00654316 Phase 1
18 Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous Meningitis Unknown status NCT00433719
19 Diagnosis of Tuberculous Meningitis by ESAT-6 in CSF Completed NCT01371916
20 Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive Dexamethasone Completed NCT01317654
21 A Prospective Household Observational Cohort Study of Influenza, Respiratory Syncytial Virus and Other Respiratory Pathogens Community Burden and Transmission Dynamics in South Africa Not yet recruiting NCT02519803

Search NIH Clinical Center for Tuberculous Meningitis

Genetic Tests for Tuberculous Meningitis

Anatomical Context for Tuberculous Meningitis

MalaCards organs/tissues related to Tuberculous Meningitis:

39
Testes, T Cells, Brain, Spinal Cord, Endothelial, B Cells, Bone

Publications for Tuberculous Meningitis

Articles related to Tuberculous Meningitis:

(show top 50) (show all 659)
id Title Authors Year
1
Comparison of clinical features and prognostic factors in HIV-negative adults with cryptococcal meningitis and tuberculous meningitis: a retrospective study. ( 28068915 )
2017
2
Recent advances in the diagnosis and management of tuberculous meningitis. ( 27798497 )
2017
3
Tuberculous meningitis and hydrocephalus in Filippino de' Medici. ( 28504108 )
2017
4
Multitargeted loop-mediated isothermal amplification for rapid diagnosis of tuberculous meningitis. ( 27084816 )
2016
5
Hyponatremia in children with tuberculous meningitis: A hospital-based cohort study. ( 27857783 )
2016
6
Hydrocephalus in tuberculous meningitis - how late can it present? ( 27417414 )
2016
7
Paradoxical reaction in tuberculous meningitis: presentation, predictors and impact on prognosis. ( 27329253 )
2016
8
Visual pathway abnormalities in tuberculous meningitis. ( 27612674 )
2016
9
Six months therapy for tuberculous meningitis. ( 27581996 )
2016
10
Looks like Tuberculous Meningitis, But Not: A Case of Rhinocerebral Mucormycosis with Garcin Syndrome. ( 27822198 )
2016
11
Antibody Detection Tests for Early Diagnosis in Tuberculous Meningitis. ( 27173078 )
2016
12
Tuberculous Meningitis in an Immunocompetent Host: A Case Report. ( 28008165 )
2016
13
Cerebrospinal fluid IgG against TB-SA for diagnosis of tuberculous meningitis. ( 26914120 )
2016
14
Corticosteroids for managing tuberculous meningitis. ( 27121755 )
2016
15
Clinical presentations, diagnosis, mortality and prognostic markers of tuberculous meningitis in Vietnamese children: a prospective descriptive study. ( 27756256 )
2016
16
Multi-drug resistant tuberculous meningitis. ( 27080792 )
2016
17
Isolated Fourth Nerve Palsy in Tuberculous Meningitis. ( 27928382 )
2016
18
Adjunctive role of MMP-9 inhibition along with conventional anti-tubercular drugs against experimental tuberculous meningitis. ( 27385155 )
2016
19
Diagnostic accuracy of interferon-gamma release assays for tuberculous meningitis: a meta-analysis. ( 26970159 )
2016
20
Estimation of cerebrospinal fluid cortisol level in tuberculous meningitis. ( 27114681 )
2016
21
Neuroimaging in tuberculous meningitis. ( 26954796 )
2016
22
Pharmacokinetics and safety/tolerability of higher oral and intravenous doses of rifampicin in adult tuberculous meningitis patients. ( 27526979 )
2016
23
Microglia activation in a pediatric rabbit model of tuberculous meningitis. ( 27935825 )
2016
24
Long-term Mortality of Patients With Tuberculous Meningitis in New York City: A Cohort Study. ( 27927856 )
2016
25
Tuberculous meningitis in an immunocompetent male complicated by hydrocephalus. ( 27758813 )
2016
26
A Case of Tuberculous Meningitis with Paradoxical Response in a 14-Year-Old Boy. ( 27807490 )
2016
27
HMGB1 level in cerebrospinal fluid as a complimentary biomarker for the diagnosis of tuberculous meningitis. ( 27795917 )
2016
28
Paroxysmal Sympathetic Hyperactivity in a Child with Tuberculous Meningitis A Case Study and Review of Related Literature. ( 27398825 )
2016
29
Safety and efficacy of additional levofloxacin in tuberculous meningitis: A randomized controlled pilot study. ( 27156611 )
2016
30
Genetic signatures of Mycobacterium tuberculosis Nonthaburi genotype revealed by whole genome analysis of isolates from tuberculous meningitis patients in Thailand. ( 27114869 )
2016
31
Validation of Thwaites Index for diagnosing tuberculous meningitis in a Colombian population. ( 27772738 )
2016
32
Cerebrospinal fluid in tuberculous meningitis exhibits only the L-enantiomer of lactic acid. ( 27267176 )
2016
33
Development tuberculous meningitis during chemotherapy for CD5-positive diffuse large B-cell lymphoma. ( 27263784 )
2016
34
Sub-optimal Specificity of Modified Ziehl-Neelsen Staining for Quick Identification of Tuberculous Meningitis. ( 28082963 )
2016
35
GeneXpert MTB/Rif to Diagnose Tuberculous Meningitis: Perhaps the First Test but not the Last. ( 26966284 )
2016
36
Evaluation of multiplex PCR using MPB64 and IS6110 primers for rapid diagnosis of tuberculous meningitis. ( 27553404 )
2016
37
Vitamin D status, vitamin D receptor and toll like receptor-2 polymorphisms in tuberculous meningitis: a case-control study. ( 27207494 )
2016
38
NaA^ve-pooled pharmacokinetic analysis of pyrazinamide, isoniazid and rifampicin in plasma and cerebrospinal fluid of Vietnamese children with tuberculous meningitis. ( 27039088 )
2016
39
Possible role of transforming growth factor I^ in tuberculous meningitis. ( 27865204 )
2016
40
Cerebral infarction pattern in tuberculous meningitis. ( 27958312 )
2016
41
Tuberculous meningitis is a major cause of mortality and morbidity in adults with central nervous system infections in Kota Kinabalu, Sabah, Malaysia: an observational study. ( 27306100 )
2016
42
Prevalence and outcome of headache in tuberculous meningitis. ( 27094524 )
2016
43
Imaging Features of the Brain, Cerebral Vessels and Spine in Pediatric Tuberculous Meningitis with Associated Hydrocephalus. ( 27213261 )
2016
44
Outcome of tuberculous meningitis in children: the first comprehensive retrospective cohort study in Indonesia. ( 27287643 )
2016
45
Predictors of Neurological Outcome of Tuberculous Meningitis in Childhood: A Prospective Cohort Study From a Developing Country. ( 27655469 )
2016
46
Use of corticosteroids in tuberculous meningitis. ( 27353808 )
2016
47
Tuberculous meningitis sequelae as basal cisternal calcifications. ( 27195045 )
2016
48
Comparative study of CD4 and CD45RO T cells and CD20 B cells in cerebrospinal fluid of syphilitic meningitis and tuberculous meningitis patients. ( 27467195 )
2016
49
CSF ADA Determination in Early Diagnosis of Tuberculous Meningitis in HIV-Infected Patients. ( 27144055 )
2016
50
Significance of immune response to Mycobacterium tuberculosis culture filtrate protein antigens in cerebrospinal fluid of tuberculous meningitis patients: A search for diagnostic marker. ( 27454259 )
2016

Variations for Tuberculous Meningitis

Expression for Tuberculous Meningitis

Search GEO for disease gene expression data for Tuberculous Meningitis.

Pathways for Tuberculous Meningitis

Pathways related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.17 ALOX5 CCL2 CCL3 CXCL8 TNF VEGFA
2
Show member pathways
12.72 CCL2 CCL3 CXCL8 TLR2 TNF
3 12.36 ALOX5 CCL2 TLR2 TNF
4
Show member pathways
12.14 ALOX5 CCL2 GGT1 TNF
5
Show member pathways
12.13 CCL2 CXCL8 TLR2 TNF
6 12.03 CXCL8 TNF VEGFA
7 11.94 CCL2 TNF VEGFA
8
Show member pathways
11.86 CCL2 CCL3 CXCL8
9 11.85 CCL2 CXCL8 TNF
10 11.75 ENO2 NPPA VEGFA
11 11.72 CXCL8 TLR2 TNF
12 11.7 CCL2 CXCL8 TNF VEGFA
13
Show member pathways
11.5 CXCL8 TNF VEGFA
14 11.42 CCL2 CCL3 CXCL8 TNF
15 11.41 ALOX5 CCL2 CXCL8 TNF VEGFA
16 11.39 CXCL8 TLR2 TNF
17 11.29 CCL2 TLR2 TNF
18 11.25 CCL2 CCL3 CXCL8 TNF
19 11.15 CCL2 CXCL8 TLR2 TNF
20 11.05 CCL2 CCL3 CXCL8 TLR2 TNF VEGFA
21 11.03 CCL2 TLR2
22 11.01 CXCL8 TNF
23 11 ALOX5 GGT1
24 10.99 CCL2 CCL3 CXCL8 TNF
25 10.89 CCL2 VEGFA
26 10.88 CXCL8 TNF
27 10.75 CCL2 CCL3 TNF
28 10.44 ALOX5 GGT1

GO Terms for Tuberculous Meningitis

Cellular components related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALOX5 CCL2 CCL3 CXCL8 LYZ NELL2
2 extracellular space GO:0005615 9.36 ADA ALOX5 CCL2 CCL3 CXCL8 ENO2

Biological processes related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

(show all 34)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.89 CCL3 TLR2 TNF VEGFA
2 immune response GO:0006955 9.85 CCL2 CCL3 CXCL8 TLR2 TNF
3 chemotaxis GO:0006935 9.83 CCL2 CCL3 CXCL8
4 regulation of cell shape GO:0008360 9.82 CCL2 CCL3 VEGFA
5 cellular response to lipopolysaccharide GO:0071222 9.8 CCL2 CXCL8 TNF
6 cellular response to tumor necrosis factor GO:0071356 9.78 CCL2 CCL3 CXCL8
7 cellular response to interleukin-1 GO:0071347 9.71 CCL2 CCL3 CXCL8
8 cellular response to organic cyclic compound GO:0071407 9.7 CCL2 CCL3 TNF
9 chemokine-mediated signaling pathway GO:0070098 9.69 CCL2 CCL3 CXCL8
10 neutrophil chemotaxis GO:0030593 9.67 CCL2 CCL3 CXCL8
11 positive regulation of T cell activation GO:0050870 9.66 ADA CCL2
12 positive regulation of protein complex assembly GO:0031334 9.65 TNF VEGFA
13 positive regulation of NF-kappaB import into nucleus GO:0042346 9.65 TLR2 TNF
14 leukotriene biosynthetic process GO:0019370 9.64 ALOX5 GGT1
15 positive regulation of heart rate GO:0010460 9.64 ADA NPPA
16 positive regulation of calcium-mediated signaling GO:0050850 9.63 ADA CCL3
17 positive regulation of calcium ion import GO:0090280 9.62 CCL2 CCL3
18 positive regulation of chemokine production GO:0032722 9.62 TLR2 TNF
19 cell activation GO:0001775 9.61 CCL3 TLR2
20 positive regulation of cell adhesion GO:0045785 9.61 CCL2 TNF VEGFA
21 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.6 CCL2 TLR2
22 induction of positive chemotaxis GO:0050930 9.58 CXCL8 VEGFA
23 positive regulation of leukocyte migration GO:0002687 9.58 CCL2 VEGFA
24 positive regulation of tumor necrosis factor production GO:0032760 9.58 CCL2 CCL3 TLR2
25 macrophage chemotaxis GO:0048246 9.57 CCL2 CCL3
26 response to molecule of bacterial origin GO:0002237 9.56 CXCL8 TLR2
27 PERK-mediated unfolded protein response GO:0036499 9.55 CCL2 CXCL8
28 response to hypoxia GO:0001666 9.55 ADA CCL2 NPPA TLR2 VEGFA
29 protein kinase B signaling GO:0043491 9.54 CCL2 CCL3 TNF
30 embryonic digestive tract development GO:0048566 9.5 ADA CXCL8 TNF
31 astrocyte cell migration GO:0043615 9.48 CCL2 CCL3
32 leukotriene metabolic process GO:0006691 9.43 ALOX5 GGT1 TLR2
33 lipopolysaccharide-mediated signaling pathway GO:0031663 9.26 CCL2 CCL3 TLR2 TNF
34 inflammatory response GO:0006954 9.17 ALOX5 CCL2 CCL3 CXCL8 LYZ TLR2

Molecular functions related to Tuberculous Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.13 CCL2 CCL3 CXCL8
2 cytokine activity GO:0005125 9.02 CCL2 CCL3 CXCL8 TNF VEGFA

Sources for Tuberculous Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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