MCID: TBR012
MIFTS: 26

Tuberculous Uveitis malady

Rare diseases category

Aliases & Classifications for Tuberculous Uveitis

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Tuberculous Uveitis, Aliases & Descriptions:

Name: Tuberculous Uveitis 41 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Summaries for Tuberculous Uveitis

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MalaCards based summary: Tuberculous Uveitis is related to uveitis and tuberculosis. An important gene associated with Tuberculous Uveitis is IFNG (interferon, gamma), and among its related pathways are 4-1BB Pathway and Leishmaniasis. The compounds interferon gamma and taurine chloramine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and liver.

Related Diseases for Tuberculous Uveitis

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Graphical network of the top 20 diseases related to Tuberculous Uveitis:



Diseases related to tuberculous uveitis

Symptoms for Tuberculous Uveitis

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Drugs & Therapeutics for Tuberculous Uveitis

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Drug clinical trials:

Search ClinicalTrials for Tuberculous Uveitis

Search NIH Clinical Center for Tuberculous Uveitis

Genetic Tests for Tuberculous Uveitis

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Anatomical Context for Tuberculous Uveitis

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MalaCards organs/tissues related to Tuberculous Uveitis:

31
Testes, Skin, Liver

Animal Models for Tuberculous Uveitis or affiliated genes

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Publications for Tuberculous Uveitis

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Articles related to Tuberculous Uveitis:

(show all 30)
idTitleAuthorsYear
1
Cost-effectiveness of alternative strategies for interferon-I^ release assays and tuberculin skin test in tuberculous uveitis. (25573149)
2015
2
Tuberculous uveitis. (25615806)
2015
3
Prospective head-to-head study comparing 2 commercial interferon gamma release assays for the diagnosis of tuberculous uveitis. (24508163)
2014
4
Liver failure following antituberculosis (ATT) chemotherapy for presumed tuberculous uveitis. (24136572)
2014
5
Tuberculous uveitis in China. (24479692)
2014
6
Tuberculous uveitis. (23450761)
2013
7
Diagnosis and treatment of tuberculous uveitis in a low endemic setting. (23706496)
2013
8
Clinical application of an in-house ELISPOT assay in patients with suspicious tuberculous uveitis and no signs of active tuberculosis. (22344468)
2012
9
Hypopyon in the context of tuberculous uveitis. (22229955)
2012
10
Cytokine and CXC chemokine expression patterns in aqueous humor of patients with presumed tuberculous uveitis. (22583692)
2012
11
Presumed tuberculous uveitis: diagnosis, management, and outcome. (21293496)
2011
12
Tuberculous uveitis. (20375860)
2010
13
Tuberculous uveitis. (20438968)
2010
14
Tuberculous uveitis. (20141860)
2010
15
Diagnosis of tuberculous uveitis: clinical application of an interferon-gamma release assay. (19576501)
2009
16
Tuberculous uveitis. (20404986)
2009
17
Strengths and weaknesses of diagnostic tools for tuberculous uveitis. (19831571)
2009
18
Tuberculous uveitis, a resurgent and underdiagnosed disease. (17486298)
2009
19
Tuberculous uveitis at a referral center in southeastern Brazil. (18345453)
2008
20
Interferon-gamma release assays in the diagnosis of tuberculous uveitis. (18804561)
2008
21
Interferon-gamma assay in tuberculous uveitis. (18369081)
2008
22
Clinical and optical coherence tomographic findings and outcome of treatment in patients with presumed tuberculous uveitis. (18034214)
2008
23
Tuberculous uveitis after treatment with etanercept. (17364199)
2007
24
Tuberculous uveitis: distribution of Mycobacterium tuberculosis in the retinal pigment epithelium. (17159041)
2006
25
A Case of Tuberculous Uveitis Complicated by Myelodysplastic Syndrome. (11033161)
2000
26
An airman with tuberculous uveitis: case study. (11439726)
2000
27
The tuberculin skin test in the diagnosis of tuberculous uveitis. (6614107)
1983
28
Tuberculous uveitis. (6849367)
1983
29
The role of the isoniazid therapeutic test in tuberculous uveitis. (6890314)
1982
30
Isoniazid in tuberculous uveitis. (13137643)
1954

Variations for Tuberculous Uveitis

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Expression for genes affiliated with Tuberculous Uveitis

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Search GEO for disease gene expression data for Tuberculous Uveitis.

Pathways for genes affiliated with Tuberculous Uveitis

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Pathways related to Tuberculous Uveitis according to GeneCards Suite gene sharing:

(show all 35)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1TNF, IFNG
2
Show member pathways
9.1IFNG, TNF
39.1IFNG, TNF
49.1TNF, IFNG
5
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.1IFNG, TNF
69.1IFNG, TNF
79.1TNF, IFNG
8
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
9.1TNF, IFNG
9
Show member pathways
Immune response CD16 signaling in NK cells58
9.1IFNG, TNF
10
Show member pathways
9.1IFNG, TNF
11
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
9.1IFNG, TNF
12
Show member pathways
9.1IFNG, TNF
13
Show member pathways
9.1IFNG, TNF
14
Show member pathways
9.1TNF, IFNG
15
Show member pathways
9.1IFNG, TNF
16
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.1IFNG, TNF
179.1IFNG, TNF
18
Show member pathways
Immune response MIF in innate immunity response58
9.1TNF, IFNG
19
Show member pathways
9.1IFNG, TNF
209.1IFNG, TNF
219.1IFNG, TNF
229.1TNF, IFNG
239.1IFNG, TNF
24
Show member pathways
9.1IFNG, TNF
259.1IFNG, TNF
26
Show member pathways
Ras signaling in the CD4+ TCR pathway36
9.1TNF, IFNG
279.1TNF, IFNG
28
Show member pathways
thioredoxin pathway36
9.1IFNG, TNF
29
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.1IFNG, TNF
309.1IFNG, TNF
31
Show member pathways
9.1TNF, IFNG
329.1IFNG, TNF
33
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.1TNF, IFNG
34
Show member pathways
IL27-mediated signaling events36
9.1TNF, IFNG
359.1IFNG, TNF

Compounds for genes affiliated with Tuberculous Uveitis

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Compounds related to Tuberculous Uveitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1interferon gamma439.6IFNG, TNF
2taurine chloramine439.6IFNG, TNF
3vesnarinone439.6IFNG, TNF
4gold sodium thiomalate439.6TNF, IFNG
5natalizumab43 1210.6IFNG, TNF
6il-12439.6IFNG, TNF
7adalimumab43 49 1211.6TNF, IFNG
8indoleamine439.6IFNG, TNF
9staurosporin439.6IFNG, TNF
10imiquimod43 59 28 1212.6TNF, IFNG
11polymyxin b439.6IFNG, TNF
12okt3439.6IFNG, TNF
13gm-csf43 2810.6TNF, IFNG
14triptolide439.5TNF, IFNG
15budesonide43 49 1211.5IFNG, TNF
16parthenolide43 210.5IFNG, TNF
17fluticasone propionate43 49 59 1212.5TNF, IFNG
18polyinosinic-polycytidylic acid439.5IFNG, TNF
192,5-oligoadenylate439.5IFNG, TNF
20rolipram43 59 2811.5TNF, IFNG
21etanercept43 49 1211.5IFNG, TNF
22poly(i-c)439.5IFNG, TNF
23il 10439.5TNF, IFNG
24mycophenolate mofetil43 49 1211.5TNF, IFNG
25l-nmma439.5IFNG, TNF
26tarc439.5TNF, IFNG
27infliximab43 49 1211.5TNF, IFNG
28glucosamine43 24 1211.5TNF, IFNG
29ivig439.5IFNG, TNF
30ccl343 2810.5TNF, IFNG
31pentoxifylline43 1210.5TNF, IFNG
32melphalan43 49 1211.5IFNG, TNF
33neopterin439.5TNF, IFNG
3415-deoxy-delta-12,14-prostaglandin j2439.4IFNG, TNF
35pdtc439.4IFNG, TNF
36thalidomide43 49 59 1212.4TNF, IFNG
37lactacystin439.4IFNG, TNF
38prednisolone43 28 1211.4IFNG, TNF
39hydrocortisone43 2 59 1212.4TNF, IFNG
40herbimycin a43 5910.4IFNG, TNF
41simvastatin43 49 59 28 24 1214.4IFNG, TNF
42endotoxin439.3TNF, IFNG
43ionomycin439.3IFNG, TNF
44tacrolimus43 49 1211.3IFNG, TNF
45calcitriol43 59 24 1212.2TNF, IFNG
46rantes439.2IFNG, TNF
47indomethacin43 28 59 1212.1IFNG, TNF
48histamine43 28 2411.1IFNG, TNF
49sb 20358043 5910.0TNF, IFNG
50butyrate438.8IFNG, TNF

GO Terms for genes affiliated with Tuberculous Uveitis

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Cellular components related to Tuberculous Uveitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.1IFNG, TNF

Biological processes related to Tuberculous Uveitis according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vitamin D biosynthetic processGO:00605579.4IFNG, TNF
2positive regulation of calcidiol 1-monooxygenase activityGO:00605599.4IFNG, TNF
3positive regulation of chemokine biosynthetic processGO:00450809.4IFNG, TNF
4positive regulation of membrane protein ectodomain proteolysisGO:00510449.4TNF, IFNG
5negative regulation of growth of symbiont in hostGO:00441309.4IFNG, TNF
6positive regulation of osteoclast differentiationGO:00456729.4IFNG, TNF
7protein import into nucleus, translocationGO:00000609.3IFNG, TNF
8positive regulation of nitric oxide biosynthetic processGO:00454299.3TNF, IFNG
9extrinsic apoptotic signaling pathwayGO:00971919.3IFNG, TNF
10humoral immune responseGO:00069599.2IFNG, TNF
11regulation of insulin secretionGO:00507969.2IFNG, TNF
12response to virusGO:00096159.1TNF, IFNG
13apoptotic processGO:00069159.1IFNG, TNF
14response to drugGO:00424939.0IFNG, TNF
15negative regulation of transcription from RNA polymerase II promoterGO:00001228.8IFNG, TNF

Molecular functions related to Tuberculous Uveitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051259.1IFNG, TNF

Products for genes affiliated with Tuberculous Uveitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Tuberculous Uveitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet