MCID: TFT001
MIFTS: 40

Tufted Angioma malady

Rare diseases, Cardiovascular diseases, Fetal diseases, Cancer diseases categories

Aliases & Classifications for Tufted Angioma

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Sources:
45NIH Rare Diseases, 51Orphanet, 65UMLS, 47Novoseek, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Tufted Angioma:

Name: Tufted Angioma 45 51 65
Nakagawa Angioblastoma 51
 
Angioma, Tufted 47
Angioma Tufted 45


Classifications:



Characteristics (Orphanet epidemiological data):

51
tufted angioma:
Inheritance: Multigenic/multifactorial,Not applicable; Age of onset: Childhood; Age of death: normal life expectancy


External Ids:

Orphanet51 1063
ICD10 via Orphanet28 D18.0
MESH via Orphanet37 C536924
UMLS via Orphanet66 C0346073

Summaries for Tufted Angioma

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Wikipedia:68 A tufted angioma (also known as an \"Acquired tufted angioma,\" \"Angioblastoma,\" \"Angioblastoma of... more...

MalaCards based summary: Tufted Angioma, also known as nakagawa angioblastoma, is related to hemangioma thrombocytopenia syndrome and hemangioendothelioma, and has symptoms including autosomal dominant inheritance, abnormality of skin pigmentation and incomplete penetrance. An important gene associated with Tufted Angioma is ENG (Endoglin), and among its related pathways are Vemurafenib Pathway, Pharmacodynamics and VEGF ligand-receptor interactions. Affiliated tissues include skin, endothelial and liver, and related mouse phenotypes are liver/biliary system and respiratory system.

Related Diseases for Tufted Angioma

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Diseases related to Tufted Angioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1hemangioma thrombocytopenia syndrome30.5FLT4, KDR
2hemangioendothelioma10.7
3kaposiform hemangioendothelioma10.7
4hemangioma10.4
5sarcoma10.4
6arteriovenous malformation10.2
7myofascial pain syndrome10.2
8herpes zoster10.2
9neurofibromatosis10.2
10angiosarcoma10.2
11capillary hemangioma10.2
12cavernous hemangioma10.2
13pyogenic granuloma10.2
14vascular malformation10.2
15endotheliitis10.2
16prostate angiosarcoma10.1FLT4, KDR
17hemangioma, capillary infantile10.1FLT4, KDR
18subglottic angioma10.1FLT4, TEK
19middle cranial fossa meningioma10.1KDR, TEK
20schizophreniform disorder10.1FLT4, PROX1
21allescheriosis10.0FLT4, PROX1
22breast cyst10.0FLT4, KDR
23cervical adenoid basal carcinoma10.0KDR, TEK
24pulmonary artery agenesis10.0ACVRL1, ENG
25vcl-related familial hypertrophic cardiomyopathy10.0ACVRL1, ENG
26skin melanoma10.0KDR, PROX1
27hidrotic ectodermal dysplasia 210.0ACVRL1, ENG
28gastric antral vascular ectasia10.0ACVRL1, ENG
29corneal ulcer10.0KDR, TEK
30vascular disease10.0ENG, FLT4, KDR
31webster deming syndrome10.0ACVRL1, ENG
32exudative vitreoretinopathy 110.0KDR, TEK
33tertiary neurosyphilis9.9ACVRL1, ENG
34carbohydrate metabolic disorder9.9FLT4, KDR, TEK
35transvestism9.9KDR, TEK
36kaposi sarcoma9.9FLT4, IFNA2, KDR
37kapur toriello syndrome9.9FLT4, KDR, PROX1
38hereditary spastic paraplegia9.9ACVRL1, ENG
39lymphoblastic lymphoma9.9FLT4, KDR, PROX1
40kidney disease9.9FLT4, IFNA2, KDR
41conjunctival folliculosis9.8ACVRL1, ENG, TEK
42venous malformations, multiple cutaneous and mucosal9.8ACVRL1, FLT4, TEK
43anterior cranial fossa meningioma9.7FLT4, KDR, PROX1, TEK
44hematologic cancer9.7FLT4, KDR, PROX1, TEK
45lymphatic system cancer9.7FLT4, IFNA2, KDR, PROX1
46renal cell carcinoma9.6FLT4, IFNA2, KDR
47tufted hair folliculitis9.0ACVRL1, ENG, FLT4, IFNA2, KDR, PROX1

Graphical network of the top 20 diseases related to Tufted Angioma:



Diseases related to tufted angioma

Symptoms for Tufted Angioma

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HPO human phenotypes related to Tufted Angioma:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 abnormality of skin pigmentation HP:0001000
3 incomplete penetrance HP:0003829
4 vascular skin abnormality HP:0011276
5 tufted angioma HP:0012329

Drugs & Therapeutics for Tufted Angioma

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Drugs for Tufted Angioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Vincristineapproved, investigationalPhase 28362068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
2
Sirolimusapproved, investigationalPhase 2174253123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
3
Miconazoleapproved, investigationalPhase 2291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
4
BenzocaineapprovedPhase 215361994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
20/20 Topical Anesthetic
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Alcohol Prep Pads
Allegenal-m
Alpha-caine Topical Anesthetic
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anbesol Jr
Anbesol Maximum Strength
Anbesol Regular Strength
Anestenka
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthetic
Anesthone
Atopalm Oral Pain Relief
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Baby Anestenka
Baby Sensigel
Baby Sensigel Night Time Formula
Baby Teething Oral Pain Reliever
Bactimicina For Sore Throat
Bencocaine Topical Anesthetic
Bensokain
Benz O Sthetic
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzodent
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
Boil Ease
Boy Butter Desensitizing Lubricant
Boy Butter Extreme Desensitizing Lubricant
Boy Butter Extreme H2O Desensitizing Lubricant
Brace Relief
Budpak Baby Teething Oral Pain Reliever
Budpak Oral Maximum Strength
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Carmex Cold Sore Treatment External Analgesic
Caswell No. 430A
Cepacol Fizzlers
Cepacol Sensations Hydra
Cepacol Sensations Sore Throat Hydra citrus splash
Cepacol Sensations Warming
Certus Sting Relief Prep Pad
Chloraseptic
Chloraseptic Warming Sore Throat
Colgate Orabase
Comfortcaine Topical Anesthetic
Cvs Fast Acting Baby Teething
Cvs Maximum Strength
Cvs Maximum Strength Boil Relief
Cvs Oral Anesthetic
Cvs Pharmacy Instant Toothache
Cvs Pharmacy Maximum Strength
Cvs Pharmacy Mouth Sore Gel
Cvs Pharmacy Nighttime Oral Pain Relief
D001566
D00552
DB01086
Dental Relief
Dentek Instant Pain Relief Maximum Strength
Dermoplast
Diet Ayds
DivK1c_000932
Dollar General Toothache Relief
Dukal Sting Relief Pad
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Finafta Baby
Finafta MultiOral
Formate, Benzocaine
Gelato Topical Anesthetic
Good Neighbor Pain Relief
Goodsense Oral Pain Relief
Gps Topical Anesthetic
Gumnumb Topical Anesthetic
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Heb Severe Toothache
Herbasoul Male Genital Desensitizer Cream
 
Hurricaine
Hurricaine Topical Anesthetic
Hurricaine Topical Anesthetic Gel
Hurricaine Topical Anesthetic Liquid
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
Insect Bite Relief
Instant Toothache Pain Relief
Intense Cvs Intense Toothache
Iodent Maximum Strength Oral Analgesic
Ismile Topical Anesthetic
Jianze Sting Relief Pads
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Kank-a Mouth Pain
Keloform
Kmart Smart Sense
Kroger Toothache Pain Relief
LS-35847
Leader Oral Analgesic
Little Colds Sore Throat Relief Melt Aways
MLS001331704
MLS002153970
Makesense Junior Pain Relief
Makesense Pain Relief
Male Desensitizer Pleasure Balm
Mandelay Male Genital Desensitizer
Mark 3
Methanesulfonate, Benzocaine
MolPort-000-871-526
Mouth Sore Medication
Mouth Sore Relief Applicator
Mouth Sore Relief Professional Strength
My Fair Baby Instant Pain Relief
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Nene Dente
Norcain
Norcaine
Norcainum
Opahl
Opahl Dye Free
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orajel For All Mouth Sores Maximum Strength
Orajel For Cold Sores
Orajel For Toothache Maximum Strength
Orajel Instant Pain Relief Maximum Strength
Orajel Instant Pain Relief Regular Strength
Orajel Instant Relief For Teething Pain
Orajel Instant Relief For Teething Pain Cooling Cucumber
Orajel Instant Relief For Teething Pain Daytime Nighttime Twin Pack
Orajel Instant Relief For Teething Pain Longer Lasting
Orajel Maximum Strength
Orajel Nighttime Instant Relief For Teething Pain Longer Lasting Extra Strength
Orajel Severe Toothache Maximum Strength Fast-Acting Formula
Oral Analgesic Maximum Strength
Oral B Instant Pain Relief
Oral Gel Maximum Strength
Oral Pain Relief Anesthetic Anesthetic
Oral Pain Reliever
Oralabs Cold Sore Treatment
Orthesin
Otocain
Outgro
Pac-dent Top Gel
Pain Relief
Pain Relief Alcohol Swabs
Parathesin
Parathesin (TN)
Parathesine
Physicians Care Sting Relief Pad
Pleasure Balm Kama Sutra
Preboost
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
Purelife Topical Anesthetic
Quality Choice Maximum Strength Oral Pain Relieving
Red Cross Oral Pain Relief
Rexall Maximum Strength
Rite Aid Baby Care
Rite Aid Liquid Anesthetic Oral Pain Relief
Rite Aid Maximum Strength
Rite Aid Oral Pain Reliever
Rite Aid Professional Strength
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Sally Hansen Ouch-relief Numbing Wipes
Sally Hansen Ouch-relief Wax Kit
Sally Hansen Ouch-relief Wax Strip Kit
Sensigel
Severe Oral Pain Reliever
Sheffield Baby Teething Gel
Sheffield Pain Relief
Shunga Male Genital Desensitizer
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Sting Relief Medicated Pad
Sting Relief Pads
Tanac
Terrasil Boil Pain Relief
Tiger Supply Inc Topical Anesthetic
Top Quality Mfg. Topical Anesthetic
Topcaine
Topcare Maximum Strength
Topical Anesthetic Banana
Topical Anesthetic Bubble Gum
Topical Anesthetic Cherry
Topical Anesthetic Mint
Topical Anesthetic Pina Colada
Topical Anesthetic Raspberry
Topical Anesthetic Strawberry
UNII-U3RSY48JW5
Ultracare Anesthetic Bubble Gum
Ultracare Anesthetic Butter Rum
Ultracare Anesthetic Creme de Menthe
Ultracare Anesthetic Pina Colada
Ultracare Anesthetic Walterberry
WLN: ZR DVO2
Walgreens Baby Teething
Walgreens Intense Toothache
Walgreens Maximum Strength
Walgreens Pain Relieving For Boils
Walgreens Severe Oral Pain Reliever
Walgreens Severe Toothache Relief
Winco Foods Maximum Strength Oral Analgesic
ZINC12358719
Zilactin-b
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
5
EverolimusapprovedPhase 21742159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
6tannic acidNutraceuticalPhase 21536

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular TumorsRecruitingNCT02110069Phase 2
2Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesActive, not recruitingNCT00975819Phase 2
3Lymphatic Anomalies RegistryRecruitingNCT02399527

Search NIH Clinical Center for Tufted Angioma

Genetic Tests for Tufted Angioma

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Anatomical Context for Tufted Angioma

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MalaCards organs/tissues related to Tufted Angioma:

33
Skin, Endothelial, Liver

Animal Models for Tufted Angioma or affiliated genes

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MGI Mouse Phenotypes related to Tufted Angioma:

38 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.6ACVRL1, FLT4, KDR, PROX1
2MP:00053888.5ACVRL1, ENG, KDR, PROX1
3MP:00053698.3ACVRL1, ENG, FLT4, KDR, TEK
4MP:00053808.3ACVRL1, ENG, FLT4, KDR, TEK
5MP:00028737.7ACVRL1, ENG, FLT4, KDR, PROX1, TEK
6MP:00053857.7ACVRL1, ENG, FLT4, KDR, PROX1, TEK
7MP:00107687.7ACVRL1, ENG, FLT4, KDR, PROX1, TEK
8MP:00053787.7ACVRL1, ENG, FLT4, KDR, PROX1, TEK
9MP:00053767.4ACVRL1, ENG, FLT4, KDR, PROX1, TEK

Publications for Tufted Angioma

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Articles related to Tufted Angioma:

(show top 50)    (show all 95)
idTitleAuthorsYear
1
A case of acquired tufted angioma in adulthood. (26312663)
2015
2
Multifocal Annular Tufted Angioma: An Uncommon Clinical Entity. (26288441)
2015
3
Tufted angioma with Kasabach-Merritt syndrome mistaken for child abuse. (25459275)
2014
4
Tufted angioma in children: report of two cases and a review of the literature. (25436158)
2014
5
Tufted angioma of the face. (23706996)
2013
6
Tufted angioma arising at a site of BCG vaccination. (23238237)
2013
7
Resection of a huge tufted angioma of orbit and orbitocranial mesh reconstruction. (23700166)
2013
8
An acquired tufted angioma of the nasal cavity. (23518006)
2013
9
Acquired tufted angioma in pregnancy showing expression of estrogen and progesterone receptors. (24185824)
2013
10
Acquired capillary hemangioma with features of tufted angioma in the external auditory canal. (23714987)
2013
11
Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases. (24044498)
2013
12
Acquired tufted angioma of upper lip: case report and review of the literature. (23526035)
2013
13
Variable response to propranolol treatment of kaposiform hemangioendothelioma, tufted angioma, and Kasabach-Merritt phenomenon. (22648868)
2012
14
Tufted angioma and myofascial pain syndrome. (21437533)
2011
15
Kasabach-merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid. (21165213)
2010
16
Expression of prox1, lymphatic endothelial nuclear transcription factor, in Kaposiform hemangioendothelioma and tufted angioma. (20975337)
2010
17
Congenital tufted angioma: Case report and review of the literature. (20492819)
2010
18
Tufted angioma associated with Kasabach-Merritt phenomenon: a therapeutic challenge. (20814640)
2010
19
Tufted angioma presented with segmental hyperpigmented plaque in a young Chinese woman. (20175859)
2010
20
Tufted angioma. (19061619)
2008
21
Tufted angioma-associated Kasabach-Merritt syndrome treated with embolization and vincristine. (18301012)
2008
22
Treatment of a tufted angioma with intense pulsed light. (17520468)
2007
23
Usefulness of D2-40 immunohistochemistry for differentiation between kaposiform hemangioendothelioma and tufted angioma. (16872472)
2006
24
Congenital, self-regressing tufted angioma. (16785378)
2006
25
Tufted angioma. (16409274)
2005
26
Partial response to treatment with recombinant interferon-alpha2a in an adult patient with tufted angioma. (14678556)
2004
27
Transformation between Kaposiform hemangioendothelioma and tufted angioma. (12771476)
2003
28
Familial predisposition to tufted angioma: identification of blood and lymphatic vascular components. (12752572)
2003
29
Retroperitoneal kaposiform hemangioendothelioma with tufted angioma-like features in an infant with Kasabach-Merritt syndrome. (14507321)
2003
30
Tufted angioma on the palm. (11737701)
2001
31
The relationship between angioblastoma (Nakagawa) and tufted angioma: report of four cases with angioblastoma and a literature-based comparison of the two conditions. (10989580)
2000
32
Tufted angioma of adult onset, revealing abundant eccrine glands and central regression. (10971067)
2000
33
Spontaneous regression of a tufted angioma. (11167986)
2000
34
Intravenous tufted angioma. (10843417)
2000
35
Acquired tufted angioma: a unique vascular lesion not previously reported in the oral mucosa. (10792235)
2000
36
Acquired tufted angioma of the lower lip mucosa. (10859727)
2000
37
Kasabach-Merritt syndrome: identification of platelet trapping in a tufted angioma by immunohistochemistry technique using monoclonal antibody to CD61. (10571842)
1999
38
Interferon for tufted angioma. (10515775)
1999
39
Acquired tufted angioma in association with a complex cutaneous vascular malformation. (10722273)
1999
40
Vascular tumors arising in port-wine stains: two cases of pyogenic granuloma and a case of acquired tufted angioma. (10659503)
1999
41
Tufted angioma, a particular form of angioma. (9252776)
1997
42
Tufted angioma: is it the same as angioblastoma (Nakagawa)? (9197842)
1997
43
Metastatic tufted angioma. (9259505)
1997
44
Tufted angioma associated with platelet trapping syndrome: response to aspirin. (9301583)
1997
45
A case of deep tufted angioma. (8632093)
1996
46
Tufted angioma of the thigh. (8034793)
1994
47
Acquired tufted angioma associated with pregnancy. (1486719)
1992
48
An eruptive vascular proliferation resembling acquired tufted angioma in the recipient of a liver transplant. (1569251)
1992
49
Tufted angioma (angioblastoma). A benign progressive angioma, not to be confused with Kaposi's sarcoma or low-grade angiosarcoma. (2644316)
1989
50
Acquired tufted angioma. (3777379)
1986

Variations for Tufted Angioma

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Expression for genes affiliated with Tufted Angioma

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Search GEO for disease gene expression data for Tufted Angioma.

Pathways for genes affiliated with Tufted Angioma

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GO Terms for genes affiliated with Tufted Angioma

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Biological processes related to Tufted Angioma according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor signaling pathwayGO:003808410.2FLT4, KDR
2cellular response to vascular endothelial growth factor stimulusGO:003592410.2FLT4, KDR
3sprouting angiogenesisGO:000204010.1FLT4, TEK
4negative regulation of endothelial cell apoptotic processGO:200035210.1KDR, TEK
5positive regulation of focal adhesion assemblyGO:005189410.1KDR, TEK
6vasculogenesisGO:000157010.0ENG, KDR
7venous blood vessel morphogenesisGO:004884510.0ENG, PROX1
8positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.9KDR, TEK
9endothelial cell differentiationGO:00454469.9KDR, PROX1
10positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.8ACVRL1, ENG
11negative regulation of endothelial cell proliferationGO:00019379.7ACVRL1, ENG
12signal transduction by protein phosphorylationGO:00230149.7ACVRL1, KDR
13positive regulation of BMP signaling pathwayGO:00305139.7ACVRL1, ENG
14lymphatic endothelial cell differentiationGO:00608369.6ACVRL1, PROX1
15lymph vessel developmentGO:00019459.5FLT4, KDR, PROX1
16BMP signaling pathwayGO:00305099.5ACVRL1, ENG
17transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.4FLT4, KDR, TEK
18protein autophosphorylationGO:00467779.3FLT4, KDR, TEK
19lymphangiogenesisGO:00019469.2ACVRL1, FLT4, PROX1
20peptidyl-tyrosine phosphorylationGO:00181089.2FLT4, KDR, TEK
21positive regulation of protein phosphorylationGO:00019349.1ENG, FLT4, KDR, TEK
22positive regulation of ERK1 and ERK2 cascadeGO:00703749.1FLT4, KDR, TEK
23vascular endothelial growth factor receptor signaling pathwayGO:00480109.1FLT4, KDR, TEK
24positive regulation of endothelial cell migrationGO:00105959.0FLT4, KDR, PROX1, TEK
25blood vessel morphogenesisGO:00485148.9ACVRL1, FLT4
26positive regulation of angiogenesisGO:00457668.9ACVRL1, KDR, TEK
27angiogenesisGO:00015258.6ACVRL1, ENG, KDR, TEK
28protein phosphorylationGO:00064688.4ACVRL1, FLT4, KDR, TEK
29positive regulation of endothelial cell proliferationGO:00019387.9ACVRL1, FLT4, KDR, PROX1, TEK

Molecular functions related to Tufted Angioma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor-activated receptor activityGO:000502110.1FLT4, KDR
2activin bindingGO:00481859.9ACVRL1, ENG
3transforming growth factor beta-activated receptor activityGO:00050249.8ACVRL1, ENG
4transforming growth factor beta bindingGO:00504319.6ACVRL1, ENG
5growth factor bindingGO:00198389.5FLT4, KDR, TEK
6protein tyrosine kinase activityGO:00047139.1FLT4, KDR, TEK
7transmembrane receptor protein tyrosine kinase activityGO:00047149.0FLT4, KDR, TEK
8protein kinase activityGO:00046728.0ACVRL1, FLT4, KDR, TEK

Sources for Tufted Angioma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet