MCID: TWN005

Twenty-Nail Dystrophy malady

Summaries for Twenty-Nail Dystrophy

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Sources:
42NIH Rare Diseases, 63Wikipedia, 32MalaCards
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NIH Rare Diseases:42 Twenty-nail dystrophy is a condition that affects the nails of the fingers and toes.  the surface of all twenty nails develop ridges, splitting, and roughening (similar to sandpaper).  the nails may also be dull and brittle. this condition most commonly occurs in childhood, but it can occur at any age.  the exact cause is unknown; but in some cases, it appears to be associated with other skin conditions such as lichen planus, eczema, psoriasis and alopecia areata. many cases of twenty-nail dystrophy that begin gradually in early childhood tend to disappear naturally as the child ages. last updated: 7/4/2012

MalaCards: Twenty-Nail Dystrophy, also known as onychodystrophy totalis, isolated, is related to lichen planus and vitiligo. Affiliated tissues include skin.

Wikipedia:63 Trachyonychia, sometimes called sandpapered nails, is a condition characterized by rough accentuated... more...

Aliases & Classifications for Twenty-Nail Dystrophy

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

twenty-nail dystrophy 42
onychodystrophy totalis, isolated 42
twenty nail dystrophy 60


Related Diseases for Twenty-Nail Dystrophy

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17GeneCards, 18GeneDecks
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Diseases related to Twenty-Nail Dystrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1lichen planus10.6
2vitiligo10.5
3alopecia10.5
4autosomal dominant nail dysplasia10.4
5ichthyosis vulgaris10.3
6alopecia universalis10.3
7alopecia areata10.3
8pachyonychia congenita10.2

Graphical network of diseases related to Twenty-Nail Dystrophy:



Diseases related to twenty-nail dystrophy

Clinical Features for Twenty-Nail Dystrophy

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Drugs & Therapeutics for Twenty-Nail Dystrophy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Twenty-Nail Dystrophy

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Anatomical Context for Twenty-Nail Dystrophy

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Sources:
32MalaCards
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MalaCards organs/tissues related to Twenty-Nail Dystrophy:

32
Skin

Animal Models for Twenty-Nail Dystrophy or affiliated genes

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Publications for Twenty-Nail Dystrophy

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Genetic Variations for Twenty-Nail Dystrophy

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Expression for genes affiliated with Twenty-Nail Dystrophy

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Sources:
15Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Twenty-Nail Dystrophy.

Pathways for genes affiliated with Twenty-Nail Dystrophy

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Compounds for genes affiliated with Twenty-Nail Dystrophy

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GO Terms for genes affiliated with Twenty-Nail Dystrophy

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Products for genes affiliated with Twenty-Nail Dystrophy

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Sources for Twenty-Nail Dystrophy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet