Aliases & Classifications for Tympanosclerosis

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Aliases & Descriptions for Tympanosclerosis:

Name: Tympanosclerosis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:1214
ICD9CM29 385.09
SNOMED-CT59 111540000
ICD1027 H74.0
UMLS65 C0155477, C0395887

Summaries for Tympanosclerosis

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Wikipedia:68 Tympanosclerosis (also known as myringosclerosis or intratympanic tympanosclerosis) is a condition... more...

MalaCards based summary: Tympanosclerosis is related to meningitis and progressive deafness with stapes fixation. An important gene associated with Tympanosclerosis is BMP2 (Bone Morphogenetic Protein 2), and among its related pathways are and Rheumatoid arthritis. Affiliated tissues include thyroid, prostate and breast.

Related Diseases for Tympanosclerosis

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Diseases related to Tympanosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 158)
idRelated DiseaseScoreTop Affiliating Genes
1meningitis30.1TLR4, TNF
2progressive deafness with stapes fixation10.4
3schizophrenia10.1
4colorectal cancer10.1
5breast cancer10.1
6lymphoma10.1
7lynch syndrome10.1
8myositis10.1
9endotheliitis10.1
10anti-hla hyperimmunization10.1TLR4, TNF
11spondylocamptodactyly10.1TLR4, TNF
12rubeosis iridis10.1TLR4, TNF
13auricular cancer10.1TLR4, TNF
14ileocolitis10.1TLR4, TNF
15idiopathic spinal cord herniation10.1TLR4, TNF
16trench fever10.1TLR4, TNF
17sarcoidosis, early-onset10.1TLR4, TNF
18liver lipoma10.1BMP2, TNF
19basilar artery occlusion10.1TLR4, TNF
20submandibular gland disease10.1TLR4, TNF
21periodontal disease10.1TLR4, TNF
22common cold10.1TLR4, TNF
23trachoma10.1TLR4, TNF
24leech infestation10.1TLR4, TNF
25porphyria10.1TLR4, TNF
26funisitis10.1TLR4, TNF
27acute gonococcal epididymo-orchitis10.1TLR4, TNF
28hypoglycemic coma10.1TLR4, TNF
29methylmalonic acidemia10.1TLR4, TNF
30necatoriasis10.1TLR4, TNF
31commensal bacterial infectious disease10.0TLR4, TNF
32hard palate cancer10.0TLR4, TNF
33carotenemia10.0TLR4, TNF
34liver leiomyosarcoma10.0TLR4, TNF
35multiple symmetric lipomatosis10.0TLR4, TNF
36mucocele of appendix10.0BMP2, CALCA
37chronic cystitis10.0TLR4, TNF
38diffuse scleroderma10.0TLR4, TNF
39congenital disorder of glycosylation, type ih10.0TLR4, TNF
40severe acute respiratory syndrome10.0TLR4, TNF
41chromosomal disease10.0BMP2, CALCA
42bone development disease10.0BMP2, CALCA
43liver fibroma10.0TLR4, TNF
44rectum signet ring adenocarcinoma10.0TLR4, TNF
45neuroblastoma10.0
46myocardial infarction10.0
47systemic lupus erythematosus10.0
48lung cancer10.0
49perry syndrome10.0
50hepatocellular carcinoma10.0

Graphical network of the top 20 diseases related to Tympanosclerosis:



Diseases related to tympanosclerosis

Symptoms for Tympanosclerosis

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Drugs & Therapeutics for Tympanosclerosis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3cCompletedNCT00422851

Search NIH Clinical Center for Tympanosclerosis

Genetic Tests for Tympanosclerosis

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Anatomical Context for Tympanosclerosis

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MalaCards organs/tissues related to Tympanosclerosis:

33
Thyroid, Prostate, Breast, Bone, Endothelial, Myeloid, Liver

Animal Models for Tympanosclerosis or affiliated genes

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Publications for Tympanosclerosis

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Articles related to Tympanosclerosis:

(show top 50)    (show all 140)
idTitleAuthorsYear
1
Executive functioning pattern as a prognostic indicator for shunt implantation surgery in patients with normal pressure hydrocephalus - A preliminary report. (26969565)
2016
2
Immunologic advances reveal new targets in psoriasis and psoriatic arthritis. (26562469)
2015
3
Metabolic Predispositions and Increased Risk of Colorectal Adenocarcinoma by Anatomical Location: A Large Population-Based Cohort Study in Norway. (26511906)
2015
4
A multicenter case-control study on screening of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in han chinese. (24777039)
2014
5
Acute sphenoid sinusitis leading to contralateral cavernous sinus thrombosis: a case report. (23883649)
2013
6
Disability, anxiety and depression associated with medication-overuse headache can be considerably reduced by detoxification and prophylactic treatment. Results from a multicentre, multinational study (COMOESTAS project). (24322480)
2013
7
Disrupted thalamic resting-state functional connectivity in patients with minimal hepatic encephalopathy. (23332976)
2013
8
Pre-Hospital Ambulance Notification and Initiation of Treatment of ST Elevation Myocardial Infarction is Associated with Significant Reduction in Door-to-Balloon Time for Primary PCI. (24388497)
2013
9
Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy. (23100283)
2013
10
The role of hematopoietic stem cell transplantation in the treatment of relapsed/refractory Hodgkin's lymphoma. (23079783)
2012
11
Preoperative chemotherapy with doxorubicin in Wilms tumor. (22146531)
2012
12
Bacterial superinfection in zoonotic cutaneous leishmaniasis. (22936185)
2012
13
Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer. (21046284)
2011
14
Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue. (20796224)
2011
15
Retention in the Golgi apparatus and expression on the cell surface of Cfr/Esl-1/Glg-1/MG-160 are regulated by two distinct mechanisms. (21777203)
2011
16
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease. (19834969)
2010
17
Bacterial vaginosis and vaginal yeast, but not vaginal cleansing, increase HIV-1 acquisition in African women. (18520679)
2008
18
Neonatal upper airway obstruction in osteogenesis imperfecta: series of three cases and review of the literature. (18254368)
2008
19
Prenatal diagnosis of DiGeorge syndrome. (19126513)
2008
20
Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers. (18665625)
2008
21
Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study. (17998499)
2007
22
Hemorrhoid with a melanocytic nevus. (17958771)
2007
23
Mineralocorticoid receptors and vascular inflammation: new answers, new questions. (17369500)
2007
24
Indication of posterior lumbar interbody fusion for lumbar disc herniation. (16760783)
2006
25
Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells. (16234819)
2005
26
Tissue factor is a useful prognostic factor of recurrence in hepatocellular carcinoma in 5-year survivors. (16201079)
2005
27
Surfactant protein D increases phagocytosis and aggregation of pollen-allergen starch granules. (15591410)
2005
28
Individual changes of gene expression in the interferon system in human blood cells due to amixin and cycloferon]. (15881395)
2005
29
Outcome of stapes surgery for otosclerosis. (15559166)
2004
30
Surgery for herniated lumbar disc disease: factors influencing outcome measures. An analysis of 403 cases. (15212116)
2004
31
Eosinophilic myocarditis in a patient with idiopathic hypereosinophilic syndrome: insights into mechanisms of myocardial cell death. (15343520)
2004
32
Contribution of transient receptor potential channels to the control of GABA release from dendrites. (14668438)
2003
33
Influence of plasma lipids, APOE genotype and type of LDL receptor gene mutations on myocardial infarction in subjects with familial hypercholesterolemia]. (12042130)
2002
34
High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis. (11929809)
2002
35
Charcot-Marie-Tooth type X: a novel mutation in the Cx32 gene with central conduction slowing. (11562788)
2001
36
Necrotizing proctitis caused by Streptococcus pyogenes. (10908025)
2000
37
Low yield of polymorphisms from EST blast searching: analysis of genes related to oxidative stress and verification of the P197L polymorphism in GPX1. (10220143)
1999
38
Molecular mechanisms of thyroid hormone-stimulated steroidogenesis in mouse leydig tumor cells. Involvement of the steroidogenic acute regulatory (StAR) protein. (10026215)
1999
39
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. (10335721)
1999
40
Hsp47 binds to the KDEL receptor and cell surface expression is modulated by cytoplasmic and endosomal pH. (9643651)
1998
41
Detection of mRNAs for urokinase-type plasminogen activator, its receptor, and type 1 inhibitor in giant cell tumors of bone with in situ hybridization. (7495280)
1995
42
Probing the bimolecular interactions of parathyroid hormone with the human parathyroid hormone/parathyroid hormone-related protein receptor. 1. Design, synthesis and characterization of photoreactive benzophenone-containing analogs of parathyroid hormone. (7654710)
1995
43
High immunoreactivity of lactoferrin contaminating commercially purified myeloperoxidase. (7963592)
1994
44
Clozapine attenuates N-methyl-D-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism. (1681442)
1991
45
Co-ordinate expression of the alpha-6 integrin laminin receptor sub-unit and laminin in breast cancer. (1662264)
1991
46
Partial deletions of a sequence family ("DXS278") and its physical linkage to steroid sulfatase as detected by pulsed-field gel electrophoresis. (1979048)
1990
47
A colorimetric assay specific for gamma-carboxyglutamic acid-containing proteins: its utility in protein purification procedures. (2363499)
1990
48
Os trigonum syndrome in a patient with multiple epiphyseal dysplasia. (7186916)
1982
49
A new familial cancer syndrome? A spectrum of malignant and benign tumors including retinoblastoma, carcinoma of the bladder and other genitourinary tumors, thyroid adenoma, and a probable case of multifocal osteosarcoma. (264592)
1977
50

Variations for Tympanosclerosis

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Expression for genes affiliated with Tympanosclerosis

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Search GEO for disease gene expression data for Tympanosclerosis.

Pathways for genes affiliated with Tympanosclerosis

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GO Terms for genes affiliated with Tympanosclerosis

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Biological processes related to Tympanosclerosis according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-8 biosynthetic processGO:004541610.0TLR4, TNF
2positive regulation of chemokine productionGO:003272210.0TLR4, TNF
3positive regulation of NF-kappaB import into nucleusGO:004234610.0TLR4, TNF
4cellular response to organic cyclic compoundGO:00714079.9BMP2, TNF
5negative regulation of interleukin-6 productionGO:00327159.9TLR4, TNF
6positive regulation of interferon-gamma productionGO:00327299.8TLR4, TNF
7organ morphogenesisGO:00098879.8BMP2, TNF
8positive regulation of ossificationGO:00457789.7BMP2, CALCA
9positive regulation of protein phosphorylationGO:00019349.7BMP2, TNF
10positive regulation of interleukin-8 productionGO:00327579.6CALCA, TLR4
11positive regulation of apoptotic processGO:00430659.6BMP2, TNF
12negative regulation of osteoclast differentiationGO:00456719.6CALCA, TLR4
13extrinsic apoptotic signaling pathwayGO:00971919.6TLR4, TNF
14I-kappaB kinase/NF-kappaB signalingGO:00072499.6TLR4, TNF
15positive regulation of interleukin-6 productionGO:00327559.6TLR4, TNF
16negative regulation of gene expressionGO:00106299.5BMP2, TNF
17defense response to Gram-negative bacteriumGO:00508299.4CALCA, TLR4
18cellular response to lipopolysaccharideGO:00712229.3TLR4, TNF
19activation of MAPK activityGO:00001879.3BMP2, TLR4, TNF
20defense response to bacteriumGO:00427429.2TLR4, TNF
21positive regulation of transcription from RNA polymerase II promoterGO:00459448.9BMP2, TLR4, TNF
22negative regulation of transcription, DNA-templatedGO:00458928.8BMP2, CALCA, TNF
23inflammatory responseGO:00069548.6BMP2, CALCA, TNF

Sources for Tympanosclerosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet