MCID: TYP027
MIFTS: 21

Type 1 Diabetes Mellitus 10

Categories: Endocrine diseases, Metabolic diseases

Aliases & Classifications for Type 1 Diabetes Mellitus 10

MalaCards integrated aliases for Type 1 Diabetes Mellitus 10:

Name: Type 1 Diabetes Mellitus 10 12 14
Diabetes Mellitus, Insulin-Dependent, 10 69
Insulin-Dependent Diabetes Mellitus 10 12
Iddm10 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110749
ICD10 32 E10
UMLS 69 C1866040

Summaries for Type 1 Diabetes Mellitus 10

Disease Ontology : 12 A type 1 diabetes mellitus that has material basis in mutation of the IL2RA gene on chromosome 10p15.1.

MalaCards based summary : Type 1 Diabetes Mellitus 10, also known as diabetes mellitus, insulin-dependent, 10, is related to diabetes mellitus, insulin-dependent, 10 and congenital aphakia. An important gene associated with Type 1 Diabetes Mellitus 10 is MTPAP (Mitochondrial Poly(A) Polymerase), and among its related pathways/superpathways are Rheumatoid arthritis and Oxidative Stress.

Related Diseases for Type 1 Diabetes Mellitus 10

Graphical network of the top 20 diseases related to Type 1 Diabetes Mellitus 10:



Diseases related to Type 1 Diabetes Mellitus 10

Symptoms & Phenotypes for Type 1 Diabetes Mellitus 10

Drugs & Therapeutics for Type 1 Diabetes Mellitus 10

Search Clinical Trials , NIH Clinical Center for Type 1 Diabetes Mellitus 10

Genetic Tests for Type 1 Diabetes Mellitus 10

Anatomical Context for Type 1 Diabetes Mellitus 10

Publications for Type 1 Diabetes Mellitus 10

Articles related to Type 1 Diabetes Mellitus 10:

# Title Authors Year
1
Stable renal function in insulin-dependent diabetes mellitus 10 years after nephrotic range proteinuria. ( 8903867 )
1996

Variations for Type 1 Diabetes Mellitus 10

Expression for Type 1 Diabetes Mellitus 10

Search GEO for disease gene expression data for Type 1 Diabetes Mellitus 10.

Pathways for Type 1 Diabetes Mellitus 10

Pathways related to Type 1 Diabetes Mellitus 10 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.75 CTLA4 CXCL12 IL17A
2 10.45 CAT SOD2

GO Terms for Type 1 Diabetes Mellitus 10

Biological processes related to Type 1 Diabetes Mellitus 10 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.65 CTLA4 CXCL12 IL16 IL17A TNFRSF10A
2 response to oxidative stress GO:0006979 9.58 CAT HMOX2 SOD2
3 response to cadmium ion GO:0046686 9.46 CAT SOD2
4 regulation of calcium ion transport GO:0051924 9.43 CXCL12 IL16
5 response to hyperoxia GO:0055093 9.37 CAT SOD2
6 induction of positive chemotaxis GO:0050930 9.32 CXCL12 IL16
7 response to hypoxia GO:0001666 9.26 CAT CXCL12 HMOX2 SOD2
8 response to L-ascorbic acid GO:0033591 9.16 CAT SOD2
9 response to radiation GO:0009314 8.8 CAT CXCL12 SOD2

Sources for Type 1 Diabetes Mellitus 10

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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