MCID: TYP014
MIFTS: 25

Type 2a Von Willebrand Disease malady

Categories: Genetic diseases, Blood diseases, Rare diseases

Aliases & Classifications for Type 2a Von Willebrand Disease

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Sources:
22GeneTests, 51Orphanet, 24GTR, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Type 2a Von Willebrand Disease:

Name: Type 2a Von Willebrand Disease 22
Von Willebrand Disease Type 2a 51 24
 
Von Willebrand Disease Type Iia 22
Von Willebrand Disease, Type 2a 65

Characteristics:

Orphanet epidemiological data:

51
von willebrand disease type 2a:
Inheritance: Autosomal dominant,Autosomal recessive

Classifications:



External Ids:

Orphanet51 166084
ICD10 via Orphanet28 D68.0
UMLS via Orphanet66 C1282968
UMLS65 C1282968

Summaries for Type 2a Von Willebrand Disease

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MalaCards based summary: Type 2a Von Willebrand Disease, also known as von willebrand disease type 2a, is related to von willebrand disease, types 2a, 2b, 2m, and 2n and rheumatoid arthritis. An important gene associated with Type 2a Von Willebrand Disease is VWF (Von Willebrand Factor). Affiliated tissues include endothelial, kidney and ovary.

Related Diseases for Type 2a Von Willebrand Disease

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Diseases related to Type 2a Von Willebrand Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1von willebrand disease, types 2a, 2b, 2m, and 2n11.8
2rheumatoid arthritis10.2
3myocardial infarction10.2
4allergic rhinitis10.2
5retinoblastoma10.2
6arthritis10.2
7hemangioma10.2
8portal hypertension10.2
9idiopathic generalized epilepsy10.2
10newcastle disease10.2
11adenocarcinoma10.2
12ischemia10.2
13rhinitis10.2
14cavernous hemangioma10.2
15posterior myocardial infarction10.2
16neuronitis10.2
17type 2b von willebrand disease9.7ADAMTS1, VWF

Graphical network of diseases related to Type 2a Von Willebrand Disease:



Diseases related to type 2a von willebrand disease

Symptoms for Type 2a Von Willebrand Disease

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Drugs & Therapeutics for Type 2a Von Willebrand Disease

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Drugs for Type 2a Von Willebrand Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Natriuretic AgentsPhase 41403
2VasopressinsPhase 4260
3HemostaticsPhase 41082
4Deamino Arginine VasopressinPhase 468
5Arginine VasopressinPhase 4264
6CoagulantsPhase 41042
7arginineNutraceuticalPhase 4364

Interventional clinical trials:

idNameStatusNCT IDPhase
1Severe Aortic Stenosis and Acquired Von Willebrand┬┤s Disease: The Impact of Desmopressin in Valve-Replacement SurgeryCompletedNCT01994330Phase 4

Search NIH Clinical Center for Type 2a Von Willebrand Disease

Genetic Tests for Type 2a Von Willebrand Disease

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Genetic tests related to Type 2a Von Willebrand Disease:

id Genetic test Affiliating Genes
1 Type 2a Von Willebrand Disease22

Anatomical Context for Type 2a Von Willebrand Disease

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MalaCards organs/tissues related to Type 2a Von Willebrand Disease:

33
Endothelial, Kidney, Ovary, Neutrophil

Animal Models for Type 2a Von Willebrand Disease or affiliated genes

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MGI Mouse Phenotypes related to Type 2a Von Willebrand Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Type 2a Von Willebrand Disease

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Articles related to Type 2a Von Willebrand Disease:

(show all 20)
idTitleAuthorsYear
1
A rare cause of intestinal obstruction: ileosigmoid knot. (25584132)
2014
2
Neutrophil-specific granule deficiency. (23294125)
2013
3
Preliminary report of multiple cell therapy for patients with multiple system atrophy. (23992875)
2013
4
Efficacy of antibiotic prophylaxis for preventing intrathoracic infections, after thoracostomy, for traumatic haemo/pneumothorax - experience of Oradea county emergency hospital. (23700905)
2012
5
Multicentric Castleman's Disease in a Hepatitis C-Positive Intravenous Drug User: A Case Report. (21577263)
2011
6
VEGF masks BNIP3-mediated apoptosis of hypoxic endothelial cells. (21318419)
2011
7
British Thoracic Society guideline for non-CF bronchiectasis. (20627931)
2010
8
A new mouse model of Peyronie's disease: an increased expression of hypoxia-inducible factor-1 target genes during the development of penile changes. (18599338)
2008
9
Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA. (18056407)
2007
10
Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy. (15871447)
2005
11
Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3. (12858162)
2003
12
Glutathione- S-transferase micro and theta gene polymorphisms as new risk factors of atopic bronchial asthma. (11862323)
2002
13
Inhibition of microsomal ATPases by high concentration of Mg2+ in tracheal epithelial cells. (11720091)
2001
14
Study on the relationship between a polymorphism of tumor necrosis factor-alpha gene and the pathogenesis of polycystic ovary syndrome]. (11775944)
2000
15
Recombinant human tumor necrosis factor receptor Fc fusion protein therapy in kidney transplant recipients undergoing OKT3 induction therapy. (9884268)
1998
16
Comparative evaluation of cell proliferative indices and epidermal growth factor receptor expression in gastric carcinoma. (9444859)
1997
17
Gastric outlet obstruction secondary to a gallstone in the duodenal bulb. (8216072)
1993
18
Effect of indomethacin in two siblings with a renin-dependent hypertension, hyperaldosteronism and hypokalemia. (7352042)
1980
19
Cerebral atrophy or hydrocephalus? (7388530)
1980
20

Variations for Type 2a Von Willebrand Disease

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Expression for genes affiliated with Type 2a Von Willebrand Disease

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Search GEO for disease gene expression data for Type 2a Von Willebrand Disease.

Pathways for genes affiliated with Type 2a Von Willebrand Disease

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GO Terms for genes affiliated with Type 2a Von Willebrand Disease

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Sources for Type 2a Von Willebrand Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet