MCID: ULC006
MIFTS: 26

Ulceroglandular Tularemia

Categories: Infectious diseases

Aliases & Classifications for Ulceroglandular Tularemia

MalaCards integrated aliases for Ulceroglandular Tularemia:

Name: Ulceroglandular Tularemia 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11990
ICD10 33 A21.0
ICD9CM 35 021.0
SNOMED-CT 64 37722001
UMLS 69 C0152941

Summaries for Ulceroglandular Tularemia

Disease Ontology : 12 A tularemia that results_in painful regional lymphadenopathy and an ulcerated skin lesion.

MalaCards based summary : Ulceroglandular Tularemia is related to tularemia and carrion's disease. An important gene associated with Ulceroglandular Tularemia is STAB2 (Stabilin 2), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Type II interferon signaling (IFNG). The drug Vaccines has been mentioned in the context of this disorder. Affiliated tissues include skin, and related phenotypes are cardiovascular system and neoplasm

Related Diseases for Ulceroglandular Tularemia

Diseases related to Ulceroglandular Tularemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
id Related Disease Score Top Affiliating Genes
1 tularemia 10.6
2 carrion's disease 10.3 CRP STAB2
3 polyarteritis nodosa 10.3 CRP PDE6B
4 muckle-wells syndrome 10.2 CASP1 CRP
5 familial mediterranean fever, ad 10.1 CASP1 CRP
6 brain sarcoma 10.1 CASP1 PDE6B STAB2
7 rift valley fever 10.1 CASP1 CRP
8 isolated growth hormone deficiency 10.1 CASP1 STAT1
9 bacterial gastritis 10.0 CRP STAT1
10 opportunistic bacterial infectious disease 10.0 CRP PDE6B
11 hepatitis 10.0
12 guillain-barre syndrome 10.0
13 pneumonia 10.0
14 keratomalacia 9.7 CASP1 CRP
15 chronic graft versus host disease 9.7 GBP1 TNFAIP6
16 spermatic cord torsion 6.4 CASP1 CRP GBP1 PDE6B PSME2 SECTM1

Graphical network of the top 20 diseases related to Ulceroglandular Tularemia:



Diseases related to Ulceroglandular Tularemia

Symptoms & Phenotypes for Ulceroglandular Tularemia

MGI Mouse Phenotypes related to Ulceroglandular Tularemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 CASP1 CRP PDE6B STAB2 STAT1 TNFSF10
2 neoplasm MP:0002006 9.02 CASP1 PSME2 STAB2 STAT1 TNFSF10

Drugs & Therapeutics for Ulceroglandular Tularemia

Drugs for Ulceroglandular Tularemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Safety and Immunogenicity Study of a Live Francisella Tularensis Vaccine Completed NCT00584844 Phase 2

Search NIH Clinical Center for Ulceroglandular Tularemia

Genetic Tests for Ulceroglandular Tularemia

Anatomical Context for Ulceroglandular Tularemia

MalaCards organs/tissues related to Ulceroglandular Tularemia:

39
Skin

Publications for Ulceroglandular Tularemia

Articles related to Ulceroglandular Tularemia:

(show all 22)
id Title Authors Year
1
Imaging Findings of Ulceroglandular Tularemia. ( 28580063 )
2017
2
Cluster of ulceroglandular tularemia cases in Slovenia. ( 27496749 )
2016
3
Ulceroglandular Tularemia Following Contact with a Boar. ( 26658527 )
2016
4
About three cases of ulceroglandular tularemia, is this the re-emergence of F. tularensis in Belgium? ( 25847026 )
2015
5
Ulceroglandular tularemia complicated by pneumonia--a case report. ( 25391005 )
2014
6
Guillain-BarrAc syndrome and ulceroglandular tularemia. ( 23712689 )
2013
7
Guillain-BarrAc syndrome and ulceroglandular tularemia. ( 23896779 )
2013
8
Ulceroglandular tularemia. ( 21501382 )
2011
9
Ulceroglandular tularemia. ( 20678093 )
2011
10
Ulceroglandular tularemia in a toddler in Germany after a mosquito bite. ( 19132387 )
2009
11
Ulceroglandular tularemia in a nonendemic area. ( 17396737 )
2007
12
Localized cutaneous infection with Francisella tularensis resembling ulceroglandular tularemia in a cat. ( 14974853 )
2004
13
Rapid laboratory diagnosis of ulceroglandular tularemia with polymerase chain reaction. ( 11440227 )
2001
14
Comparative analysis of PCR versus culture for diagnosis of ulceroglandular tularemia. ( 10618057 )
2000
15
Index of suspicion. Case 2. Diagnosis: ulceroglandular tularemia. ( 8992473 )
1996
16
Use of RNA hybridization in the diagnosis of a case of ulceroglandular tularemia. ( 1702055 )
1990
17
Ulceroglandular tularemia: a typical case of relapse. ( 2606733 )
1989
18
Tick-borne ulceroglandular tularemia. ( 6579402 )
1983
19
Hepatic abscess complicating ulceroglandular tularemia. ( 6652596 )
1983
20
GUILLAIN-BARRE SYNDROME ASSOCIATED WITH ULCEROGLANDULAR TULAREMIA. ( 14215606 )
1964
21
Ulceroglandular tularemia treated by chloromycetin. ( 24541925 )
1952
22
Ulceroglandular tularemia treated with streptomycin; a report of two cases. ( 18908319 )
1948

Variations for Ulceroglandular Tularemia

Expression for Ulceroglandular Tularemia

Search GEO for disease gene expression data for Ulceroglandular Tularemia.

Pathways for Ulceroglandular Tularemia

Pathways related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.17 CASP1 STAT1
2 10.52 GBP1 STAT1
3 10.16 CRP PDE6B STAT1

GO Terms for Ulceroglandular Tularemia

Cellular components related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 CASP1 CRP GBP1 SECTM1 TNFAIP6 TNFSF10

Biological processes related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.43 CASP1 PDE6B SECTM1 STAT1 TNFAIP6 TNFSF10
2 interferon-gamma-mediated signaling pathway GO:0060333 9.26 GBP1 STAT1
3 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 8.85 TNFSF10
4 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 8.8 CASP1 SECTM1 TNFSF10

Molecular functions related to Ulceroglandular Tularemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor binding GO:0005164 9.26 STAT1 TNFSF10
2 hyaluronic acid binding GO:0005540 9.16 STAB2 TNFAIP6
3 low-density lipoprotein particle binding GO:0030169 8.96 CRP STAB2
4 identical protein binding GO:0042802 8.8 GBP1 PSME2 STAT1

Sources for Ulceroglandular Tularemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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