MCID: UNX002

Unexplained Intellectual Disability malady

Category: Rare diseases

Aliases & Classifications for Unexplained Intellectual Disability

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Aliases & Descriptions for Unexplained Intellectual Disability:

Name: Unexplained Intellectual Disability 54

Classifications:



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Summaries for Unexplained Intellectual Disability

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MalaCards based summary: Unexplained Intellectual Disability is related to intellectual disability. An important gene associated with Unexplained Intellectual Disability is DDX3X (DEAD-Box Helicase 3, X-Linked). Affiliated tissues include thyroid.

Related Diseases for Unexplained Intellectual Disability

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Diseases related to Unexplained Intellectual Disability via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1intellectual disability10.1

Symptoms & Phenotypes for Unexplained Intellectual Disability

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Drugs & Therapeutics for Unexplained Intellectual Disability

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Drugs for Unexplained Intellectual Disability (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CopperapprovedPhase 317215158-11-9, 7440-50-827099
Synonyms:
 
Copper
Cu
2MicronutrientsPhase 35802
3Trace ElementsPhase 35802
4histidineNutraceuticalPhase 342

Interventional clinical trials:

idNameStatusNCT IDPhase
1Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper DeficiencyRecruitingNCT00811785Phase 3
2Identification of Early Predictors of Fetomaternal HemorrhageCompletedNCT01232387
3Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.Active, not recruitingNCT01916018

Search NIH Clinical Center for Unexplained Intellectual Disability

Genetic Tests for Unexplained Intellectual Disability

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Anatomical Context for Unexplained Intellectual Disability

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MalaCards organs/tissues related to Unexplained Intellectual Disability:

36
Thyroid

Publications for Unexplained Intellectual Disability

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Articles related to Unexplained Intellectual Disability:

idTitleAuthorsYear
1
Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling. (26235985)
2015
2
Challenges and opportunities in the investigation of unexplained intellectual disability using family-based whole-exome sequencing. (25081361)
2014
3
High prevalence of array comparative genomic hybridization abnormalities in adults with unexplained intellectual disability. (20009761)
2010

Variations for Unexplained Intellectual Disability

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Expression for genes affiliated with Unexplained Intellectual Disability

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Search GEO for disease gene expression data for Unexplained Intellectual Disability.

Pathways for genes affiliated with Unexplained Intellectual Disability

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GO Terms for genes affiliated with Unexplained Intellectual Disability

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Sources for Unexplained Intellectual Disability

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet