MCID: UPP004
MIFTS: 46

Upper Respiratory Tract Disease

Categories: Respiratory diseases

Aliases & Classifications for Upper Respiratory Tract Disease

MalaCards integrated aliases for Upper Respiratory Tract Disease:

Name: Upper Respiratory Tract Disease 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:974
ICD9CM 35 478.1 478.19
SNOMED-CT 64 195823002 266346007
ICD10 33 J39.8
UMLS 69 C0029581

Summaries for Upper Respiratory Tract Disease

Disease Ontology : 12 A respiratory system disease which involves the upper respiratory tract.

MalaCards based summary : Upper Respiratory Tract Disease is related to cytoplasmic body myopathy and x-linked intellectual disability, van esch type. An important gene associated with Upper Respiratory Tract Disease is TLR9 (Toll Like Receptor 9), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Azithromycin and Cefuroxime have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and heart, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Upper Respiratory Tract Disease

Diseases related to Upper Respiratory Tract Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 203)
id Related Disease Score Top Affiliating Genes
1 cytoplasmic body myopathy 10.9 IL13 IL5
2 x-linked intellectual disability, van esch type 10.9 IL4 IL5 RNASE3
3 toxic diffuse goiter 10.9 IL13 IL5 RNASE3
4 orbital plasma cell granuloma 10.9 IL4 IL5 RNASE3
5 myofibroma 10.9 IL13 IL5 TLR9
6 anterior dislocation of lens 10.8 CCL11 IL4 RNASE3
7 heart septal defect 10.8 CD79A RNASE3
8 crustacean allergy 10.8 CD79A IL5 RNASE3
9 papillary follicular thyroid adenocarcinoma 10.8 IL5 RNASE3
10 lymphocytic gastritis 10.8 CCL11 IL5 RNASE3
11 cannabis abuse 10.8 CCL11 IL5 RNASE3
12 cherry allergy 10.8 IL13 IL4 IL5
13 vulvar disease 10.8 CD79A RHNO1 RNASE3
14 anti-basement membrane glomerulonephritis 10.8 CD79A CXCL8
15 abdominal tuberculosis 10.8 IL13 IL4 IL5
16 acute necrotizing encephalopathy type 1 10.8 IL13 IL5 TLR9
17 glucose intolerance 10.8 IL13 IL4 IL5
18 aniseikonia 10.8 CD79A IL4 RHNO1
19 cutaneous ganglioneuroma 10.8 CD79A IL4 RHNO1
20 acute ackee fruit intoxication 10.8 IL4 TNF
21 adenoiditis 10.8
22 laryngotracheitis 10.8
23 uvulitis 10.8
24 adenoid hypertrophy 10.8
25 tonsillitis 10.8
26 common cold 10.8
27 acute laryngopharyngitis 10.8
28 pharyngitis 10.8
29 scarlet fever 10.8
30 epiglottitis 10.8
31 spindle cell variant squamous cell breast carcinoma 10.8 IL13 IL4 IL5
32 philophthalmiasis 10.8 CD79A IL4 IL5
33 exophthalmos 10.8 CXCL8 IL5 RNASE3
34 penis agenesis 10.8 CCL11 IL5
35 tracheomalacia 10.8 CYSLTR1 RHNO1 TRPV1
36 epidermolysis bullosa simplex superficialis 10.8 CD79A IL4 RNASE3
37 whistling face syndrome, recessive form 10.8 CXCL8 IL5 RNASE3
38 marasmus 10.8 IL4 IL5 RNASE3 TRPV1
39 psychotic disorder 10.8 CCL11 CXCL8 IL4
40 aortic arch interruption 10.8 IL13 IL5 TNF
41 retinal vascular disease 10.7 CCL11 CXCL8 IL4
42 urethral intrinsic sphincter deficiency 10.7 IL4 IL5 TNF
43 brucella canis brucellosis 10.7 TLR9 TNF TRPV1
44 signet ring cell adenocarcinoma 10.7 IL5 RNASE3 TNF
45 combined thymoma 10.7 CD79A MUC5B
46 malignant hyperthermia 10.7 IL4 IL5 TLR9
47 winchester syndrome 10.7 IL13 IL4 IL5 RNASE3
48 common peroneal nerve lesion 10.7 CXCL8 IL5
49 purpura fulminans 10.7 IL13 IL4 IL5 RNASE3
50 acute gonococcal prostatitis 10.7 IL13 IL4 IL5 RNASE3

Graphical network of the top 20 diseases related to Upper Respiratory Tract Disease:



Diseases related to Upper Respiratory Tract Disease

Symptoms & Phenotypes for Upper Respiratory Tract Disease

MGI Mouse Phenotypes related to Upper Respiratory Tract Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 CCL11 CD79A HRH1 IL13 IL33 IL4
2 homeostasis/metabolism MP:0005376 9.97 CD79A HRH1 IL13 IL33 IL4 IL5
3 immune system MP:0005387 9.83 IL13 IL33 IL4 IL5 MS4A2 MUC5B
4 respiratory system MP:0005388 9.28 IL5 MUC5B TNF TSLP CCL11 CYSLTR1

Drugs & Therapeutics for Upper Respiratory Tract Disease

Drugs for Upper Respiratory Tract Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 659)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
2
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
3
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
4
Clarithromycin Approved Phase 4 81103-11-9 84029
5
Moxifloxacin Approved, Investigational Phase 4,Phase 1 354812-41-2, 151096-09-2 152946
6
Penicillin G Approved, Vet_approved Phase 4 61-33-6 5904
7
Piperacillin Approved Phase 4 66258-76-2 43672
8
Tazobactam Approved Phase 4 89786-04-9 123630
9
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
10
Montelukast Approved Phase 4,Phase 3 158966-92-8 5281040
11 Beractant Approved Phase 4 108778-82-1
12 Poractant alfa Approved Phase 4 129069-19-8
13
Rivaroxaban Approved Phase 4 366789-02-8
14
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2 2078-54-8 4943
15
Ribavirin Approved Phase 4,Phase 3,Phase 2 36791-04-5 37542
16
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
17
Zinc Approved Phase 4,Phase 3,Phase 2 7440-66-6 32051 23994
18
Budesonide Approved Phase 4,Phase 3 51333-22-3 63006 5281004
19
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
20 Racepinephrine Approved Phase 4,Phase 3,Phase 2
21
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
22
Omalizumab Approved, Investigational Phase 4,Phase 2,Phase 3 242138-07-4
23
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1 75614-87-8, 51-45-6 774
24
Pemetrexed Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 150399-23-8, 137281-23-3 446556 60843
25
Lidocaine Approved, Vet_approved Phase 4,Phase 3 137-58-6 3676
26
Ketamine Approved, Vet_approved Phase 4,Phase 3 6740-88-1 3821
27
Benzocaine Approved Phase 4,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
28
Menthol Approved Phase 4,Phase 3,Phase 1,Phase 2 2216-51-5 16666
29
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
30
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
31
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 26787-78-0 33613 2171
32
Ephedrine Approved Phase 4,Phase 3,Phase 2 299-42-3 9294
33
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2 90-82-4 7028
34
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 22916-47-8 4189
35
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
36
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
37
Remifentanil Approved Phase 4 132875-61-7 60815
38
Ethanol Approved Phase 4,Phase 3 64-17-5 702
39
Eplerenone Approved Phase 4 107724-20-9 150310 443872
40
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
41
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2 55-56-1 9552079 2713
42
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
43
Bisoprolol Approved Phase 4 66722-44-9 2405
44
Carvedilol Approved, Investigational Phase 4 72956-09-3 2585
45
Clevidipine Approved Phase 4 167221-71-8
46
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
47
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
48
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
49
Bosentan Approved, Investigational Phase 4,Phase 3 147536-97-8 104865
50
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635

Interventional clinical trials:

(show top 50) (show all 1263)

id Name Status NCT ID Phase Drugs
1 A Post-marketing Research on Jinyebaidu Granule in Treating Patients With Acute Upper Respiratory Infection Unknown status NCT02539277 Phase 4 Jinyebaidu granule;Fufangshuanghua granule;Jinyebaidu granule placebo;Fufangshuanghua granule placebo
2 AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation Unknown status NCT01460108 Phase 4
3 Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections Unknown status NCT02171338 Phase 4
4 Determining the Minimal Effective Volume (MEAV95) for Interscalene Brachial Plexus Block for Surgical Anesthesia Unknown status NCT01703130 Phase 4
5 Simple Verbal Intervention for Adequately Collecting Sputum Unknown status NCT01135043 Phase 4
6 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
7 Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients Unknown status NCT01131806 Phase 4 fluticasone/ salmeterol 125/25 mcg/puff;fluticasone/ salmeterol 250/25 mcg/puff
8 Inflammatory Response to Anti Inflammatory Therapy in Children With Sleep Disordered Breathing Unknown status NCT00299910 Phase 4 Montelukast
9 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4 Poractant alfa instillation;Beractant instillation
10 Validation of Functional Imaging as Predictive Tool for Outcome of Mandibular Replacement Appliance Therapy in Obstructive Sleep Apnea Hypopnea Syndrome Patients Unknown status NCT01524510 Phase 4
11 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
12 Anti-inflammatory Effects of Rivaroxaban Versus Dabigatran Unknown status NCT02331602 Phase 4 Rivaroxaban;Dabigatran
13 Influenza Vaccination in Patients With Scleroderma Unknown status NCT01002508 Phase 4
14 Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis Unknown status NCT01301703 Phase 4
15 Safety and Efficacy of Intradermal Trivalent Influenza Vaccination in Institutionalized Older Adults Unknown status NCT01967368 Phase 4 Intanza;Vaxigrip
16 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
17 Trial of Chinese Herbal Medicine in the Treatment of Upper Respiratory Tract Infections (URTIs) Completed NCT00887172 Phase 4 Jing Fang Bai Du san;Placebo;Ying Qiao san
18 DIAMANTE - Diseases Infectious Analysis Microflora Antibiotic Effect Completed NCT00424905 Phase 4 Bacillus clausii
19 Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin Completed NCT01464944 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Paracetamol;Placebo
20 The Efficacy and Safety Study of Fuganlin Oral Liquid in Children With Influenza (Acute Upper Respiratory Infection) Completed NCT02622659 Phase 4 Fuganlin Oral Liquid;Xiaoer Jiebiao Oral Liquid
21 Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds Completed NCT00189475 Phase 4 Montelukast
22 Effect of Lactobacillus Reuteri in Cystic Fibrosis Completed NCT01737983 Phase 4
23 Remifentanil and Laryngeal Reflex Responses in Pediatric Patients With URI Completed NCT00611195 Phase 4 propofol, remifentanil
24 Compliance And Safety Study In Children With Upper And Lower Respiratory Tract Infections Completed NCT00939185 Phase 4 Azithromycin
25 A Study to Evaluate the Efficacy of the Nasal Antiseptic, PrevinC, When Administered for the RiskReduction of Rhinitis in Subjects Who Work for Child Day Care Centers Completed NCT02225912 Phase 4
26 Intermittent Use of Aerosolized Ribavirin for Treatment of RSV Completed NCT00500578 Phase 4 Ribavirin;Ribavirin
27 Reduction of Left Ventricular Hypertrophy After Eplerenone Therapy Completed NCT03186742 Phase 4 Eplerenone 50 mg Tab
28 Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children. Completed NCT01968434 Phase 4 carbocisteine cough syrup
29 PulmonarOM (Bacterial Lysates) in Respiratory Tract Infections Completed NCT00599417 Phase 4 Bacterial Lysates;placebo
30 Prevention of Respiratory Infections and MAnagement Among Children (PRIMAKid) Completed NCT00161122 Phase 4
31 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
32 Vitamin A and Zinc: Prevention of Pneumonia (VAZPOP) Study Completed NCT00228254 Phase 4 Zinc (12.5 mg/day);vitamin A 10,000 IU per week
33 Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients. Completed NCT01329276 Phase 4 Symbicort® forte Turbohaler®
34 Clinical Trial of Fluticasone Versus Placebo at the Onset of a Cold for Children With Asthma Completed NCT00238927 Phase 4 inhaled fluticasone 750 mcg/day twice daily until 2 days without symptoms (maximum 15 consecutive days)
35 SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study Completed NCT01150383 Phase 4
36 Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies Completed NCT01658280 Phase 4
37 Study of the Effect of Probiotics on Respiratory Morbidity After Influenza Vaccination of Elderly in Nursing Homes Completed NCT00849277 Phase 4 Lactobacillus casei Shirota
38 Immunogenicity, Safety and Tolerability of a Trivalent Subunit Inactivated Vaccine in Healthy Subjects 50 Years and Above Completed NCT01867021 Phase 4
39 Symptomatic Treatment of Common Cold Symptoms Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
40 Inspire® Upper Airway Stimulation (UAS) System German Post-Market Study Completed NCT02293746 Phase 4
41 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
42 Efficacy of Nebulised Beclometasone in Viral Wheezing Prophylaxis Completed NCT01265342 Phase 4 Beclomethasone;Placebo
43 Lung Function and Patient Preference With QVA149 vs. Tiotropium in COPD Patients Completed NCT02125734 Phase 4 QVA149;Tiotropium
44 Nebulized 5% Hypertonic Saline for the Treatment of Bronchiolitis Completed NCT01016249 Phase 4 Treatment 1. (5% Hypertonic saline + Epinephrine);Treatment 3. (3% Hypertonic saline + Epinephrine);Treatment 2. (Normal saline + Epinephrine)
45 Serotonin and the Upper Airway in Obstructive Sleep Apnea Completed NCT00100464 Phase 4 Paroxetine;5HTP
46 Beta Blocker Therapy in Moderate to Severe COPD Completed NCT01656005 Phase 4
47 Clevidipine for Vasoreactivity Evaluation of the Pulmonary Arterial Bed Completed NCT01121458 Phase 4 Clevidipine
48 Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea Completed NCT01344759 Phase 4 Dexmedetomidine;Propofol
49 Age-adjusted D-dimer Cut-off Levels to Rule Out Pulmonary Embolism Completed NCT01134068 Phase 4
50 A Trial of Acetazolamide Versus Placebo in Preventing Mountain Sickness During Rapid Ascent Completed NCT01418157 Phase 4 Acetazolamide;Placebo

Search NIH Clinical Center for Upper Respiratory Tract Disease

Genetic Tests for Upper Respiratory Tract Disease

Anatomical Context for Upper Respiratory Tract Disease

MalaCards organs/tissues related to Upper Respiratory Tract Disease:

39
Lung, Testes, Heart, Endothelial, Tongue, Liver, Colon

Publications for Upper Respiratory Tract Disease

Articles related to Upper Respiratory Tract Disease:

(show top 50) (show all 53)
id Title Authors Year
1
Prevalence of feline herpesvirus-1, feline calicivirus, Chlamydophila felis and Mycoplasma felis DNA and associated risk factors in cats in Spain with upper respiratory tract disease, conjunctivitis and/or gingivostomatitis. ( 26919892 )
2016
2
Exposure of rhesus monkeys to cowpox virus Brighton Red by large-particle aerosol droplets results in an upper respiratory tract disease. ( 27166137 )
2016
3
Detection of feline upper respiratory tract disease pathogens using a commercially available real-time PCR test. ( 26324635 )
2015
4
Sampling sites for detection of feline herpesvirus-1, feline calicivirus and Chlamydia felis in cats with feline upper respiratory tract disease. ( 25660223 )
2015
5
Mycoplasmosis and upper respiratory tract disease of tortoises: a review and update. ( 24951264 )
2014
6
Surveillance for upper respiratory tract disease and Mycoplasma in free-ranging gopher tortoises (Gopherus polyphemus) in Georgia, USA. ( 25098305 )
2014
7
An association between Helicobacter pylori and upper respiratory tract disease: fact or fiction? ( 24587622 )
2014
8
Effects of mycoplasmal upper-respiratory-tract disease on movement and thermoregulatory behavior of gopher tortoises (Gopherus polyphemus) in Georgia, USA. ( 25121399 )
2014
9
Impacts of upper respiratory tract disease on olfactory behavior of the Mojave desert tortoise. ( 24506425 )
2014
10
Mycoplasmal upper respiratory tract disease across the range of the threatened Mojave Desert tortoise: associations with thermal regime and natural antibodies. ( 23579813 )
2013
11
Surveillance of upper respiratory tract disease in owned cats in Australia, 2009-2012. ( 23910025 )
2013
12
Comparison of the efficacy of amoxicillin-clavulanic acid, cefovecin, and doxycycline in the treatment of upper respiratory tract disease in cats housed in an animal shelter. ( 22765368 )
2012
13
Upper respiratory tract disease in captive orangutans (Pongo sp.): prevalence in 20 European zoos and predisposing factors. ( 21770970 )
2011
14
Infectious causes for feline upper respiratory tract disease--a case-control study. ( 20851008 )
2010
15
Detection of bacterial and viral organisms from the conjunctiva of cats with conjunctivitis and upper respiratory tract disease. ( 20817584 )
2010
16
Effects of mycoplasmal upper respiratory tract disease on morbidity and mortality of gopher tortoises in northern and central Florida. ( 20688675 )
2010
17
Flow cytometric method for quantifying viable Mycoplasma agassizii, an agent of upper respiratory tract disease in the desert tortoise (Gopherus agassizii). ( 20132436 )
2010
18
Upper respiratory tract disease, force of infection, and effects on survival of gopher tortoises. ( 19425439 )
2009
19
Descriptive epidemiology of feline upper respiratory tract disease in an animal shelter. ( 19782625 )
2009
20
Efficacy of pradofloxacin in cats with feline upper respiratory tract disease due to Chlamydophila felis or Mycoplasma infections. ( 18289288 )
2008
21
Risk factors for time to diagnosis of feline upper respiratory tract disease in UK animal adoption shelters. ( 18639946 )
2008
22
Prevalence of selected infectious organisms and comparison of two anatomic sampling sites in shelter cats with upper respiratory tract disease. ( 18539065 )
2008
23
An investigation into the role of Chlamydophila spp. in bovine upper respiratory tract disease. ( 16624729 )
2006
24
Nasal levels of nitric oxide as an outcome variable in allergic upper respiratory tract disease: Influence of atopy and hayfever on nNO. ( 17063731 )
2006
25
Factors associated with upper respiratory tract disease caused by feline herpesvirus, feline calicivirus, Chlamydophila felis and Bordetella bronchiseptica in cats: experience from 218 European catteries. ( 15908495 )
2005
26
Correlation of rhinoscopic signs of inflammation with histologic findings in nasal biopsy specimens of cats with or without upper respiratory tract disease. ( 15328715 )
2004
27
Mycoplasma testudineum sp. nov., from a desert tortoise (Gopherus agassizii) with upper respiratory tract disease. ( 15388705 )
2004
28
Upper respiratory tract disease in tortoises. ( 14509583 )
2003
29
Occurrence of infectious upper respiratory tract disease and response to vaccination in horses on six sentinel premises in northern Colorado. ( 12553466 )
2003
30
An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in Japan. ( 11999440 )
2002
31
Feline upper respiratory tract disease. ( 10907225 )
2000
32
Pathology of upper respiratory tract disease of gopher tortoises in Florida. ( 10813609 )
2000
33
A study of feline upper respiratory tract disease with reference to prevalence and risk factors for infection with feline calicivirus and feline herpesvirus. ( 11716607 )
2000
34
Prevalence of feline Chlamydia psittaci and feline herpesvirus 1 in cats with upper respiratory tract disease. ( 10357102 )
1999
35
Seroepidemiology of upper respiratory tract disease in the desert tortoise in the western Mojave Desert of California. ( 10574531 )
1999
36
Upper respiratory tract disease in the gopher tortoise is caused by Mycoplasma agassizii. ( 10364595 )
1999
37
Upper respiratory tract disease and mycoplasmosis in desert tortoises from Nevada. ( 9391959 )
1997
38
Comparison of Chlamydia psittaci from cats with upper respiratory tract disease by polymerase chain reaction analysis of the ompA gene. ( 9106964 )
1997
39
Relationship between clinical signs of upper respiratory tract disease and antibodies to Mycoplasma agassizii in desert tortoises from Nevada. ( 9131556 )
1997
40
Molecular characterization of Pasteurella testudinis isolated from desert tortoises (Gopherus agassizii) with and without upper respiratory tract disease. ( 7563420 )
1995
41
Mycoplasma agassizii causes upper respiratory tract disease in the desert tortoise. ( 7927724 )
1994
42
Detection of antibodies to a pathogenic mycoplasma in desert tortoises (Gopherus agassizii) with upper respiratory tract disease. ( 8314986 )
1993
43
Chronic upper respiratory tract disease of free-ranging desert tortoises (Xerobates agassizii). ( 2067052 )
1991
44
Bacterial adherence and upper respiratory tract disease: a correlation between S. pyogenes attachment and recurrent throat infections. ( 3066104 )
1988
45
Epidemiology of equine upper respiratory tract disease on standardbred racetracks. ( 218705 )
1979
46
Intranasal vaccination against upper respiratory tract disease (U.R.D.) in the cat--II. Results of field studies under enzootic conditions in the Netherlands with a combined vaccine containing live attenuated calici- and herpesvirus. ( 757151 )
1978
47
Intranasal vaccination against upper respiratory tract disease (U.R.D.) in the cat--I. Virological and serological observations in cats suffering from U.R.D. ( 757150 )
1978
48
Office diagnosis of streptococcal upper respiratory tract disease. ( 1091982 )
1975
49
Viral isolation rates during summer from children with acute upper respiratory tract disease and healthy children. ( 4358333 )
1974
50
Bacterial and viral throat flora. Comparison of findings in children with acute upper respiratory tract disease and in healthy controls during winter. ( 4396432 )
1971

Variations for Upper Respiratory Tract Disease

Expression for Upper Respiratory Tract Disease

Search GEO for disease gene expression data for Upper Respiratory Tract Disease.

Pathways for Upper Respiratory Tract Disease

Pathways related to Upper Respiratory Tract Disease according to GeneCards Suite gene sharing:

(show all 26)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.98 CCL11 CD79A CXCL8 IL13 IL33 IL4
2
Show member pathways
13.28 CCL11 CXCL8 IL13 IL33 IL4 IL5
3
Show member pathways
12.76 CXCL8 IL13 IL33 IL4 TLR9 TNF
4
Show member pathways
12.71 CCL11 CXCL8 IL13 IL4 IL5 MS4A2
5
Show member pathways
12.57 CD79A IL13 IL4 IL5 MS4A2 TNF
6
Show member pathways
12.15 CCL11 CXCL8 IL4 TLR9 TNF
7
Show member pathways
12.14 IL13 IL4 IL5 TSLP
8
Show member pathways
12.13 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
9
Show member pathways
12.1 CXCL8 IL13 IL4 IL5 TNF
10 11.94 CD79A IL4 IL5 PTGDR2 TNF
11 11.91 CCL11 CXCL8 IL13 IL4 TNF
12 11.79 IL4 IL5 TNF
13 11.79 CXCL8 IL13 IL4 IL5
14
Show member pathways
11.75 CXCL8 IL4 IL5 TNF
15 11.69 IL4 IL5 TLR9 TNF
16 11.6 IL13 IL33 IL4 IL5 PTGDR2 TNF
17 11.59 CCL11 IL4 IL5
18 11.5 CXCL8 IL13 IL4 TNF
19 11.46 CXCL8 TLR9 TNF
20 11.39 CCL11 IL13 IL33 IL4 IL5
21 11.21 IL13 IL4 IL5 TNF
22 11.17 IL13 IL4 IL5
23 11.11 CCL11 CXCL8 IL13 IL4 IL5 TNF
24 10.97 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
25 10.94 IL13 IL33 IL4 IL5 TNF TSLP
26 10.88 IL13 IL4 IL5

GO Terms for Upper Respiratory Tract Disease

Cellular components related to Upper Respiratory Tract Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.9 CCL11 CXCL8 IL13 IL33 IL4 IL5
2 external side of plasma membrane GO:0009897 9.43 CD79A IL13 IL4 MS4A2 TNF TRPV1
3 extracellular space GO:0005615 9.36 CCL11 CXCL8 IL13 IL33 IL4 IL5

Biological processes related to Upper Respiratory Tract Disease according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.89 CD79A CYSLTR1 MS4A2 TRPV1
2 chemotaxis GO:0006935 9.72 CCL11 CXCL8 CYSLTR1 IL4 PTGDR2
3 positive regulation of interleukin-6 production GO:0032755 9.65 IL33 TLR9 TNF
4 response to molecule of bacterial origin GO:0002237 9.58 CXCL8 TLR9
5 positive regulation of immunoglobulin secretion GO:0051024 9.58 IL33 IL5
6 positive regulation of podosome assembly GO:0071803 9.57 IL5 TNF
7 positive regulation of mast cell degranulation GO:0043306 9.56 IL13 IL4
8 immune response GO:0006955 9.56 CCL11 CXCL8 IL13 IL4 IL5 MS4A2
9 positive regulation of chemokine biosynthetic process GO:0045080 9.55 IL4 TNF
10 eosinophil chemotaxis GO:0048245 9.54 CCL11 HRH1
11 microglial cell activation GO:0001774 9.54 IL13 IL4 TRPV1
12 positive regulation of interleukin-13 production GO:0032736 9.52 IL33 IL4
13 type 2 immune response GO:0042092 9.49 IL33 IL4
14 regulation of proton transport GO:0010155 9.46 IL13 IL4
15 positive regulation of mononuclear cell migration GO:0071677 9.43 IL4 TNF
16 negative regulation of complement-dependent cytotoxicity GO:1903660 9.4 IL13 IL4
17 positive regulation of B cell proliferation GO:0030890 9.33 IL13 IL4 IL5
18 inflammatory response GO:0006954 9.28 CCL11 CXCL8 HRH1 IL13 IL5 MS4A2
19 positive regulation of immunoglobulin production GO:0002639 9.26 IL13 IL4
20 signal transduction GO:0007165 10.16 CCL11 CXCL8 CYSLTR1 HRH1 IL13 MS4A2

Molecular functions related to Upper Respiratory Tract Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.23 CCL11 CXCL8 IL13 IL33 IL4 IL5

Sources for Upper Respiratory Tract Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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