MCID: URC003
MIFTS: 22

Urachal Adenocarcinoma

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Urachal Adenocarcinoma

MalaCards integrated aliases for Urachal Adenocarcinoma:

Name: Urachal Adenocarcinoma 50 69
Adenocarcinoma of the Urachus 50

Classifications:



Summaries for Urachal Adenocarcinoma

MalaCards based summary : Urachal Adenocarcinoma, also known as adenocarcinoma of the urachus, is related to bladder urachal adenocarcinoma and adenocarcinoma. An important gene associated with Urachal Adenocarcinoma is AFP (Alpha Fetoprotein). The drugs Cisplatin and Fluorouracil have been mentioned in the context of this disorder. Affiliated tissues include ovary, prostate and breast.

Related Diseases for Urachal Adenocarcinoma

Diseases related to Urachal Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
id Related Disease Score Top Affiliating Genes
1 bladder urachal adenocarcinoma 11.9
2 adenocarcinoma 10.6
3 urethral obstruction sequence 9.9 AFP CEACAM5
4 clear cell variant infiltrating bladder urothelial carcinoma 9.9 AFP CEACAM5
5 intestine carcinoma in situ 9.9 AFP CEACAM5
6 nodular medulloblastoma 9.9 AFP CEACAM5
7 gingival hypertrophy 9.9 AFP CEACAM5
8 prostatitis 9.9
9 uveal melanoma 9.8 AFP CEACAM5
10 varicocele 9.8 AFP CEACAM5
11 testicular trophoblastic tumor 9.8 AFP CEACAM5
12 pigmented villonodular synovitis 9.8 AFP CEACAM5
13 sphenoid sinus squamous cell carcinoma 9.8 AFP CEACAM5
14 malignant peritoneal solitary fibrous tumor 9.8 AFP CEACAM5
15 tricuspid valve insufficiency 9.8 AFP CEACAM5
16 urethral villous adenoma 9.8 AFP CEACAM5
17 epidermolysis bullosa, junctional, herlitz type 9.8 AFP CEACAM5
18 anterolateral myocardial infarction 9.7 AFP CEACAM5
19 peritoneal serous adenocarcinoma 9.7 AFP CEACAM5
20 sleep disorder 9.7 AFP CEACAM5
21 lymphoma 9.7
22 dermatomyositis 9.7
23 urethritis 9.7
24 cystadenocarcinoma 9.7
25 mucinous cystadenocarcinoma 9.7
26 breast mucinous carcinoma 9.7
27 peritonitis 9.7
28 appendicitis 9.7
29 urachal cyst 9.7
30 ectodermal dysplasia with natal teeth, turnpenny type 9.7 AFP CEACAM5
31 gallbladder cancer 9.7 AFP CEACAM5
32 brown-vialetto-van laere syndrome 9.6 AFP CEACAM5
33 acute porphyria 9.6 AFP CEACAM5
34 solitary osseous plasmacytoma 9.5 AFP CEACAM5
35 hepatocellular carcinoma 9.5 AFP CEACAM5
36 gastric cancer, somatic 9.4 AFP CEACAM5
37 gastric fundus cancer 9.2 AFP CEACAM5

Graphical network of the top 20 diseases related to Urachal Adenocarcinoma:



Diseases related to Urachal Adenocarcinoma

Symptoms & Phenotypes for Urachal Adenocarcinoma

Drugs & Therapeutics for Urachal Adenocarcinoma

Drugs for Urachal Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
2
Fluorouracil Approved Phase 2 51-21-8 3385
3
Gemcitabine Approved Phase 2 95058-81-4 60750
4
Levoleucovorin Approved Phase 2 68538-85-2
5
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
6 Anti-Infective Agents Phase 2
7 Antimetabolites Phase 2
8 Antimetabolites, Antineoplastic Phase 2
9 Antiviral Agents Phase 2
10 Immunosuppressive Agents Phase 2
11 tyrosine Nutraceutical Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant Active, not recruiting NCT00082706 Phase 2 5-Fluorouracil (5-FU);Leucovorin;Cisplatin;Gemcitabine
2 Cabozantinib for Advanced Urothelial Cancer Active, not recruiting NCT01688999 Phase 2 Cabozantinib

Search NIH Clinical Center for Urachal Adenocarcinoma

Genetic Tests for Urachal Adenocarcinoma

Anatomical Context for Urachal Adenocarcinoma

MalaCards organs/tissues related to Urachal Adenocarcinoma:

39
Ovary, Prostate, Breast, Kidney, Colon, Brain

Publications for Urachal Adenocarcinoma

Articles related to Urachal Adenocarcinoma:

(show top 50) (show all 66)
id Title Authors Year
1
Absence of GNAS and BRAF mutations but presence of KRAS mutation in urachal adenocarcinoma. ( 28285720 )
2017
2
Response to: Absence of GNAS and BRAF mutations but presence of KRAS mutation in urachal adenocarcinoma. ( 28666639 )
2017
3
Response to: Absence of GNAS and BRAF mutations but presence of KRAS mutation in urachal adenocarcinoma: author reply. ( 28666644 )
2017
4
Urachal adenocarcinoma: a rare case report. ( 28228881 )
2017
5
Fine Needle Aspiration Cytology Diagnosis of an Urachal Adenocarcinoma. ( 27190817 )
2016
6
Urachal Adenocarcinoma in a Dog. ( 27009748 )
2016
7
Extended partial cystectomy with augmentation cystoplasty in urachal adenocarcinoma: An oncologically favorable but underutilized alternative to radical cystectomy. ( 27453665 )
2016
8
Urachal adenocarcinoma incidentally discovered in a young woman at elective caesarean section. ( 27353172 )
2016
9
Urachal adenocarcinoma that metastasized to breast was misinterpreted as primary breast mucinous carcinoma: A rare case report and literature review. ( 27583877 )
2016
10
Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations. ( 27078850 )
2016
11
Rare presentation of urachal adenocarcinoma with skip metastasis to colon. ( 27555687 )
2016
12
Bladder sparing robot-assisted laparoscopic en bloc resection of urachus and umbilicus for urachal adenocarcinoma. ( 26531120 )
2015
13
Urachal adenocarcinoma of the bladder, our experience in 20 years. ( 25774825 )
2015
14
En Bloc Robot-assisted Laparoscopic Partial Cystectomy, Urachal Resection, and Pelvic Lymphadenectomy for Urachal Adenocarcinoma. ( 26029004 )
2015
15
Response to targeted therapy in urachal adenocarcinoma. ( 25568747 )
2014
16
Unusual presentation of urachal adenocarcinoma with genitourinary cutaneous metastasis. ( 25337842 )
2014
17
18FDG PET/CT findings in the unusual urachal adenocarcinoma. ( 24566402 )
2014
18
A Comprehensive Review of Pediatric Urachal Anomalies and Predictive Analysis for Adult Urachal Adenocarcinoma Development. ( 25219697 )
2014
19
High-stage urachal adenocarcinoma can be associated with microsatellite instability and KRAS mutations. ( 24355196 )
2014
20
Combined modalities treatment of pulmonary metastasis from an urachal adenocarcinoma. ( 24179644 )
2013
21
A rare cause of urachal adenocarcinoma: urachal diverticle. ( 23476880 )
2013
22
A rare case of recurrent urachal adenocarcinoma of the bladder. ( 23914577 )
2013
23
The different morphologies of urachal adenocarcinoma do not discriminate genomically by micro-RNA expression profiling. ( 23528864 )
2013
24
Outcomes of Korean patients with clinically localized urachal or non-urachal adenocarcinoma of the bladder. ( 21458312 )
2013
25
Urachal adenocarcinoma. Case report and bibliographic review. ( 22619143 )
2012
26
Urachal adenocarcinoma: big dimensions without involvement of the bladder wall. ( 22641501 )
2012
27
Urachal adenocarcinoma: a clinician's guide for treatment. ( 23040259 )
2012
28
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for patients with peritoneal carcinomatosis secondary to urachal adenocarcinoma. ( 22271499 )
2012
29
A case of metastatic urachal adenocarcinoma treated with several different chemotherapeutic regimens. ( 22396380 )
2012
30
Prostatic urethral recurrence of urachal adenocarcinoma. ( 21900110 )
2011
31
Alpha-methylacyl-coenzyme a racemase-expressing urachal adenocarcinoma of the abdominal wall. ( 20664785 )
2010
32
Urachal adenocarcinoma metastatic to the ovaries resembling primary ovarian mucinous carcinoma: a case report with the immunohistochemical study. ( 21228934 )
2010
33
Urachal adenocarcinoma with late brain metastases. ( 20945591 )
2010
34
Treatment of metastatic urachal adenocarcinoma in a young woman: a case report. ( 20062662 )
2009
35
Robotic assisted laparoscopic partial cystectomy and urachal resection for urachal adenocarcinoma. ( 19860941 )
2009
36
Enteric type urachal adenocarcinoma: a case report. ( 19671231 )
2009
37
Urachal adenocarcinoma following kidney transplantation: the first case report. ( 19545760 )
2009
38
Laparoscopic treatment of mucinous urachal adenocarcinoma with mucocele. ( 19238053 )
2009
39
Urachal adenocarcinoma. ( 18554640 )
2008
40
Urachal adenocarcinoma masquerading as an urachal cyst. ( 23133041 )
2008
41
Laparoscopic partial cystectomy with en bloc resection of the urachus for urachal adenocarcinoma. ( 17880303 )
2007
42
Laparoscopic en bloc partial cystectomy with bilateral pelvic lymphadenectomy for urachal adenocarcinoma. ( 16618570 )
2006
43
Urachal adenocarcinoma: incidental finding at the time of surgery for ruptured appendicitis. ( 17212903 )
2006
44
Ovarian metastases from an urachal adenocarcinoma. ( 16257483 )
2006
45
An isolated vertebral metastasis of urachal adenocarcinoma. ( 15338559 )
2004
46
Large intestinal type-urachal adenocarcinoma with focal expression of prostatic specific antigen. ( 15509213 )
2004
47
Urachal adenocarcinoma metastatic to the ovaries: case report and literature review. ( 12649676 )
2003
48
Recurrent urachal adenocarcinoma. ( 14600142 )
2003
49
Dermatomyositis associated with urachal adenocarcinoma. ( 12352426 )
2002
50
An unusual malignancy in a young female; urachal adenocarcinoma. ( 12678132 )
2001

Variations for Urachal Adenocarcinoma

Expression for Urachal Adenocarcinoma

Search GEO for disease gene expression data for Urachal Adenocarcinoma.

Pathways for Urachal Adenocarcinoma

GO Terms for Urachal Adenocarcinoma

Sources for Urachal Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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