MCID: URM001
MIFTS: 24

Uremic Neuropathy

Categories: Nephrological diseases, Neuronal diseases

Aliases & Classifications for Uremic Neuropathy

MalaCards integrated aliases for Uremic Neuropathy:

Name: Uremic Neuropathy 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4675
NCIt 47 C27055
SNOMED-CT 64 11659006
UMLS 69 C0268708

Summaries for Uremic Neuropathy

MalaCards based summary : Uremic Neuropathy is related to neuropathy and pyosalpinx. An important gene associated with Uremic Neuropathy is PTH (Parathyroid Hormone). The drugs Fexofenadine and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include kidney.

Related Diseases for Uremic Neuropathy

Graphical network of the top 20 diseases related to Uremic Neuropathy:



Diseases related to Uremic Neuropathy

Symptoms & Phenotypes for Uremic Neuropathy

Drugs & Therapeutics for Uremic Neuropathy

Drugs for Uremic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fexofenadine Approved Phase 4 83799-24-0 3348
2
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
3
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
4
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
5 Analgesics Phase 4
6 Anti-Allergic Agents Phase 4
7 Anti-Anxiety Agents Phase 4
8 Anticonvulsants Phase 4
9 calcium channel blockers Phase 4
10 Calcium, Dietary Phase 4
11 Central Nervous System Depressants Phase 4
12 Histamine Antagonists Phase 4
13 Histamine H1 Antagonists Phase 4
14 Histamine H1 Antagonists, Non-Sedating Phase 4
15
Histamine Phosphate Phase 4 51-74-1 65513
16 Neurotransmitter Agents Phase 4
17 Peripheral Nervous System Agents Phase 4
18 Psychotropic Drugs Phase 4
19 Tranquilizing Agents Phase 4
20 Olive Nutraceutical Phase 1, Phase 2
21 Omega 3 Fatty Acid Nutraceutical Phase 1, Phase 2
22
Hydrogen peroxide Approved, Vet_approved 7722-84-1 784
23
Biotin Approved, Nutraceutical 58-85-5 171548
24 Antibodies
25 Immune Sera
26 Immunoglobulins
27 Paraform
28 Dialysis Solutions
29 Disinfectants
30 Pharmaceutical Solutions
31 Vitamin B7 Nutraceutical

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Pregabalin for the Treatment of Uremic Pruritus Unknown status NCT01852318 Phase 4 pregabalin 75mg daily for 12 weeks;fexofenadine 60 mg daily for 12 weeks;placebo
2 Treatment of Uremic Pruritus by Olive-omega 3 Ointment Unknown status NCT01447693 Phase 1, Phase 2
3 Small-fiber Neuropathy in Chronic Kidney Disease Unknown status NCT01078857
4 Functional Electrical Stimulation in Chronic Kidney Disease Unknown status NCT02336776
5 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Recruiting NCT01793168
6 Low-level Laser Therapy in Chronic Kidney Disease Active, not recruiting NCT02944760
7 Expanded Hemodialysis Versus Online Hemodiafiltration Not yet recruiting NCT03274518
8 Inspiratory Muscle Training in Chronic Kidney Disease Not yet recruiting NCT03082404

Search NIH Clinical Center for Uremic Neuropathy

Genetic Tests for Uremic Neuropathy

Anatomical Context for Uremic Neuropathy

MalaCards organs/tissues related to Uremic Neuropathy:

39
Kidney

Publications for Uremic Neuropathy

Articles related to Uremic Neuropathy:

(show top 50) (show all 51)
id Title Authors Year
1
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain-Barre Syndrome. ( 28706599 )
2017
2
Impact of nocturnal hemodialysis on peripheral uremic neuropathy. ( 26264143 )
2015
3
Uremic neuropathy. ( 23931805 )
2013
4
Rapid reversal of uremic neuropathy following renal transplantation in an adolescent. ( 22188489 )
2012
5
Exploring the potential of flunarizine for Cisplatin-induced painful uremic neuropathy in rats. ( 22087421 )
2011
6
A case of an accelerated uremic neuropathy. ( 21401366 )
2011
7
Clinical course of uremic neuropathy in long-term hemodialysis. ( 18982751 )
2008
8
Uremic neuropathy: clinical features and new pathophysiological insights. ( 17195171 )
2007
9
Uremic neuropathy and the analysis of electrophysiological changes. ( 11284054 )
2001
10
Features of uremic neuropathy in long-term dialysis. ( 10097427 )
1998
11
Uremic neuropathy. A case presentation. ( 1663549 )
1991
12
Nerve conduction studies and vibration perception thresholds in diabetic and uremic neuropathy. ( 1848989 )
1991
13
Effect of hemodialysis and hemodiafiltration on uremic neuropathy. ( 1668062 )
1991
14
Axoplasmic electrolyte contents measured by X-ray microanalysis in experimental uremic neuropathy. ( 2174479 )
1990
15
Recovery of uremic neuropathy after renal transplantation. ( 2154362 )
1990
16
Uremic neuropathy and treatment with renal transplantation. ( 2549887 )
1989
17
The effects of hemodialysis with different membranes on middle molecules and uremic neuropathy. ( 2538398 )
1989
18
The natural history of uremic neuropathy. ( 2844471 )
1988
19
Proximal vs. distal nerve conduction measurements in uremic neuropathy. ( 2854787 )
1988
20
Polymethylmethacrylate in chronic hemodialysis. Is it of benefit in patients with uremic neuropathy? ( 3675957 )
1987
21
Rapid improvement of uremic neuropathy on short high-efficiency hemodialysis with special reference to middle molecules. ( 3675953 )
1987
22
Transplant osteonecrosis: can it be due to uremic neuropathy? ( 2821420 )
1987
23
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. II. Is plasma myoinositol a uremic neurotoxin? ( 3427262 )
1986
24
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. I. Development of chronic renal failure in rats. ( 3427261 )
1986
25
Vibratory perception threshold compared with nerve conduction velocity in the evaluation of uremic neuropathy. ( 4003031 )
1985
26
Uremic neuropathy: clinical and neurophysiological investigation of dialysis patients using different chemical membranes. ( 4065159 )
1985
27
Evaluation of uremic neuropathy by visual (VEP) and brainstem auditory (BAEP) evoked potentials. ( 3837513 )
1985
28
Thermal sensitivity in uremic neuropathy. ( 4003032 )
1985
29
Control of uremic neuropathy by equilibrium peritoneal dialysis. ( 6329962 )
1984
30
Experimental uremic neuropathy. Part 2. Sodium permeability decrease and inactivation in potential clamped nerve fibers. ( 6088705 )
1984
31
Improvement of uremic neuropathy and hypogeusia by dialysate zinc supplementation: a double-blind study. ( 6330425 )
1983
32
Progress of peripheral uremic neuropathy during continuous ambulatory peritoneal dialysis (CAPD). ( 6298985 )
1982
33
Uremic neuropathy: correlations between electroneurographic parameters and serum levels of parathyroid hormone and aluminum. ( 6293832 )
1982
34
Detection of uremic neuropathy by reflex response latency. ( 6251176 )
1980
35
Tibial nerve H-reflex and F-wave studies in patients with uremic neuropathy. ( 6252459 )
1980
36
Motor nerve conduction indicators in uremic neuropathy. ( 7356822 )
1980
37
H-reflex latency in uremic neuropathy: correlation with NCV and clinical findings. ( 224838 )
1979
38
Uremic neuropathy: evidence of middle molecule toxicity. ( 687020 )
1978
39
Electrophysiologic changes in uremic neuropathy after successful renal transplantation. ( 176611 )
1976
40
Letter: Carbamazepine in uremic neuropathy. ( 176912 )
1976
41
Uremic neuropathy. III. Controlled study of restricted protein and fluid diet and infrequent hemodialysis versus conventional hemodialysis treatment. ( 171524 )
1975
42
Uremic neuropathy. Monitoring of transketolase activity inhibition in a child. ( 4265477 )
1973
43
Effect of hemodialysis on the inhibition of nervous tissue transketolase and on uremic neuropathy. ( 5158138 )
1971
44
Effects of renal transplantation on uremic neuropathy. A clinical and electrophysiologic study. ( 4324615 )
1971
45
Uremic neuropathy. ( 4328348 )
1971
46
Segmental demyelination secondary to axonal degeneration in uremic neuropathy. ( 4326086 )
1971
47
Transketolase inhibition as a mechanism in uremic neuropathy. ( 5164301 )
1971
48
Recovery from uremic neuropathy. ( 4324616 )
1971
49
Observations on plasma magnesium levels in patients with uremic neuropathy under treatment by periodic hemodialysis. ( 5466463 )
1970
50
Uremic neuropathy. ( 4378313 )
1967

Variations for Uremic Neuropathy

Expression for Uremic Neuropathy

Search GEO for disease gene expression data for Uremic Neuropathy.

Pathways for Uremic Neuropathy

GO Terms for Uremic Neuropathy

Biological processes related to Uremic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to cadmium ion GO:0046686 8.62 B2M PTH

Molecular functions related to Uremic Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 EPO PTH

Sources for Uremic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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