MCID: URM001
MIFTS: 26

Uremic Neuropathy malady

Categories: Nephrological diseases, Neuronal diseases

Aliases & Classifications for Uremic Neuropathy

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Aliases & Descriptions for Uremic Neuropathy:

Name: Uremic Neuropathy 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:4675
SNOMED-CT62 11659006
NCIt45 C27055

Summaries for Uremic Neuropathy

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MalaCards based summary: Uremic Neuropathy is related to neuropathy and anal buschke-lowenstein tumor, and has symptoms including uraemia odour An important gene associated with Uremic Neuropathy is PTH (Parathyroid Hormone). Affiliated tissues include kidney.

Related Diseases for Uremic Neuropathy

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Graphical network of the top 20 diseases related to Uremic Neuropathy:



Diseases related to uremic neuropathy

Symptoms & Phenotypes for Uremic Neuropathy

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UMLS symptoms related to Uremic Neuropathy:


uraemia odour

Drugs & Therapeutics for Uremic Neuropathy

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Drugs for Uremic Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Gabapentinapproved, investigationalPhase 428960142-96-33446
Synonyms:
1-(Aminomethyl)-cyclohexaneacetic acid
1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(aminomethyl)cyclohexyl]acetic acid
60142-96-3
AC-1485
AC1L1FYE
AC1Q53PH
AKOS000280865
Aclonium
Apo-Gabapentin
Apotex brand of gabapentin
Aventis brand of gabapentin
BB_SC-1512
BIDD:GT0656
BPBio1_000993
BRN 2359739
BSPBio_000901
C040029
C9H17NO2
CAS-60142-96-3
CCRIS 7210
CHEBI:188316
CHEBI:42797
CHEMBL940
CI 945
CI-945
CID3446
D00332
DB00996
DDS-2003
DM-1796
DM-5689
EINECS 262-076-3
EU-0100582
G-154
G0318
G154_SIGMA
GBN
GOE 2450
Gabapen
Gabapentin
Gabapentin (JAN/USAN/INN)
Gabapentin GR
Gabapentin Hexal
Gabapentin Stada
Gabapentin [USAN:INN:BAN]
Gabapentin-ratiopharm
Gabapentina
Gabapentine
Gabapentine [INN-French]
Gabapentino
Gabapentino [INN-Spanish]
Gabapentino [Spanish]
Gabapentinum
 
Gabapentinum [INN-Latin]
Gabapetin
Go 3450
Goe-3450
HMS1570N03
HMS2089J03
HSDB 7364
Hexal brand of gabapentin
I06-0677
L000733
LS-7194
Lopac-G-154
Lopac0_000582
MLS000069358
MolPort-000-883-862
NCGC00015466-01
NCGC00015466-02
NCGC00015466-06
NCGC00015466-09
NCGC00016891-01
NCGC00021545-02
NCGC00021545-04
NCGC00021545-05
NSC742194
Neurontin
Neurontin (TN)
Novo-Gabapentin
Novo-Gabapentine
Novopharm brand of gabapentin
PMS-Gabapentin
Parke Davis brand of gabapentin
Pfizer brand of gabapentin
Pharmascience brand of gabapentin
Prestwick0_000861
Prestwick1_000861
Prestwick2_000861
Prestwick3_000861
Prestwick_151
S2133_Selleck
SMR000058311
SPBio_002822
STK598009
Serada
Stadapharm brand of gabapentin
TL8003814
Tocris-0806
UNII-6CW7F3G59X
Vultin
Warner-Lambert brand of gabapentin
[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
gabapentin
gabapentin (Neurontin)
gabapentina
gabapentinium
ratiopharm brand of gabapentin
2
FexofenadineapprovedPhase 46183799-24-03348
Synonyms:
159389-12-5
2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid
2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid
4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
76815-58-2
83799-24-0
AC1L1FQB
Allegra
Allegra-D 12 Hour
Allegra-D 24 Hour
BRD-A73368467-003-02-8
BSPBio_003521
C06999
C32H39NO4
CHEBI:5050
CHEMBL914
CID3348
Carboxyterfenadine
D07958
DB00950
EU-0100488
F 9427
Fexofenadine
Fexofenadine (INN)
Fexofenadine [INN:BAN]
Fexofenadine hydrochloride
Fexofendine
HSDB 7486
KBio2_002449
 
KBio2_005017
KBio2_007585
KBio3_002742
KBioGR_000807
KBioSS_002456
L000869
LS-28827
Lopac0_000488
MDL 16455
MolPort-002-508-207
NCGC00015453-03
NCGC00015453-06
NCGC00092389-02
NCGC00092389-03
SPBio_001197
STK624102
STOCK6S-26154
Spectrum2_001179
Spectrum3_001921
Spectrum4_000204
Spectrum5_001474
Spectrum_001914
Telfast
Telfast (TN)
Terfenadine acid metabolite
Terfenadine carboxylate
Terfenadine-COOH
Terfenidine carboxylate, MDL 16455
UNII-E6582LOH6V
fexofenadine
3
Pregabalinapproved, illicit, investigationalPhase 4355148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
4
HistamineapprovedPhase 4103475614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
5
Histamine PhosphateapprovedPhase 4103351-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
6Histamine H1 Antagonists, Non-SedatingPhase 4354
7AnalgesicsPhase 411287
8Tranquilizing AgentsPhase 44164
9Psychotropic DrugsPhase 46279
10Peripheral Nervous System AgentsPhase 422776
11Histamine H1 AntagonistsPhase 4782
12Neurotransmitter AgentsPhase 417734
13Anti-Anxiety AgentsPhase 41816
14Anti-Allergic AgentsPhase 41490
15AnticonvulsantsPhase 42620
16calcium channel blockersPhase 41940
17Central Nervous System DepressantsPhase 412806
18Calcium, DietaryPhase 45525
19Histamine AntagonistsPhase 4946
20Omega 3 Fatty AcidNutraceuticalPhase 1, Phase 2969
21OliveNutraceuticalPhase 1, Phase 2258
22
Biotinapproved, nutraceutical4358-85-5171548
Synonyms:
(+)-Biotin
(+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valerate
(+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid
(3AS,4S,6ar)-hexahydro-2-oxo-1H-thieno[3,4-D]imidazole-4-valeric acid
(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-D]imidazole-4-valerate
(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-D]imidazole-4-valeric acid
-(+)-biotin
1swk
1swn
1swr
5-(2-Oxohexahydro-1H-thieno[3,4-D]imidazol-4-yl)pentanoate
5-(2-Oxohexahydro-1H-thieno[3,4-D]imidazol-4-yl)pentanoic acid
Biodermatin
Bioepiderm
Bios II
Bios h
Biotin
Biotina
Biotine
Biotinum
Coenzyme R
D(+)-Biotin
 
D-(+)-Biotin
D-Biotin
D-Biotin factor S
Factor S
Factor S (vitamin)
Hexahydro-2-oxo-1H-thieno(3,4-D)imidazole-4-pentanoate
Hexahydro-2-oxo-1H-thieno(3,4-D)imidazole-4-pentanoic acid
Hexahydro-2-oxo-[3aS-(3aa,4b,6aa)]-1H-Thieno[3,4-D]imidazole-4-pentanoate
Hexahydro-2-oxo-[3aS-(3aa,4b,6aa)]-1H-Thieno[3,4-D]imidazole-4-pentanoic acid
Hexahydro-2-oxo-[3as-(3alpha,4beta,6alpha)]-1H-Thieno[3,4-D]imidazole-4-pentanoate
Hexahydro-2-oxo-[3as-(3alpha,4beta,6alpha)]-1H-Thieno[3,4-D]imidazole-4-pentanoic acid
Lutavit H2
Meribin
Rovimix H 2
Vitamin B7
Vitamin H
Vitamin-h
cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valerate
cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid
cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid
cis-Tetrahydro-2-oxothieno(3,4-D)imidazoline-4-valeric acid
delta-(+)-Biotin
delta-Biotin
delta-Biotin factor S
23Paraform3
24Immunoglobulins6045
25Immunoglobulin G265
26Immune Sera10
27
Hydrogen peroxide557722-84-1784
Synonyms:
Adeka Super EL
Albone
Albone 35
Albone DS
Anti-Keim 50
Asepticper
Baquashock
CIX
Clarigel Gold
Crestal Whitestrips
Crystacide
Dentasept
Deslime LP
Hioxyl
Hipox
Hybrite
Hydrogen dioxide
Hydrogen peroxide
Inhibine
Lase Peroxide
Lensan A
 
Magic Bleaching
Metrokur
Mirasept
Nite White Excel 2
Odosat D
Opalescence Xtra
Oxigenal
Oxydol
Oxyfull
Oxysept
Oxysept I
Pegasyl
Perhydrol
Perone
Peroxaan
Peroxclean
Quasar Brite
Select Bleach
Superoxol
T-Stuff
Whiteness HP
Whitespeed
Xtra White
28Antibodies6045
29Vitamin B7Nutraceutical43

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pregabalin for the Treatment of Uremic PruritusUnknown statusNCT01852318Phase 4
2Treatment of Uremic Pruritus by Olive-omega 3 OintmentUnknown statusNCT01447693Phase 1, Phase 2
3Small-fiber Neuropathy in Chronic Kidney DiseaseUnknown statusNCT01078857
4Functional Electrical Stimulation in Chronic Kidney DiseaseUnknown statusNCT02336776
5Low-level Laser Therapy in Chronic Kidney DiseaseActive, not recruitingNCT02944760

Search NIH Clinical Center for Uremic Neuropathy

Genetic Tests for Uremic Neuropathy

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Anatomical Context for Uremic Neuropathy

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MalaCards organs/tissues related to Uremic Neuropathy:

36
Kidney

Publications for Uremic Neuropathy

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Articles related to Uremic Neuropathy:

(show all 50)
idTitleAuthorsYear
1
Impact of nocturnal hemodialysis on peripheral uremic neuropathy. (26264143)
2015
2
Uremic neuropathy. (23931805)
2013
3
Rapid reversal of uremic neuropathy following renal transplantation in an adolescent. (22188489)
2012
4
Exploring the potential of flunarizine for Cisplatin-induced painful uremic neuropathy in rats. (22087421)
2011
5
A case of an accelerated uremic neuropathy. (21401366)
2011
6
Clinical course of uremic neuropathy in long-term hemodialysis. (18982751)
2008
7
Uremic neuropathy: clinical features and new pathophysiological insights. (17195171)
2007
8
Uremic neuropathy and the analysis of electrophysiological changes. (11284054)
2001
9
Features of uremic neuropathy in long-term dialysis. (10097427)
1998
10
Uremic neuropathy. A case presentation. (1663549)
1991
11
Effect of hemodialysis and hemodiafiltration on uremic neuropathy. (1668062)
1991
12
Nerve conduction studies and vibration perception thresholds in diabetic and uremic neuropathy. (1848989)
1991
13
Recovery of uremic neuropathy after renal transplantation. (2154362)
1990
14
Axoplasmic electrolyte contents measured by X-ray microanalysis in experimental uremic neuropathy. (2174479)
1990
15
The effects of hemodialysis with different membranes on middle molecules and uremic neuropathy. (2538398)
1989
16
Uremic neuropathy and treatment with renal transplantation. (2549887)
1989
17
Proximal vs. distal nerve conduction measurements in uremic neuropathy. (2854787)
1988
18
The natural history of uremic neuropathy. (2844471)
1988
19
Rapid improvement of uremic neuropathy on short high-efficiency hemodialysis with special reference to middle molecules. (3675953)
1987
20
Transplant osteonecrosis: can it be due to uremic neuropathy? (2821420)
1987
21
Polymethylmethacrylate in chronic hemodialysis. Is it of benefit in patients with uremic neuropathy? (3675957)
1987
22
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. II. Is plasma myoinositol a uremic neurotoxin? (3427262)
1986
23
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. I. Development of chronic renal failure in rats. (3427261)
1986
24
Vibratory perception threshold compared with nerve conduction velocity in the evaluation of uremic neuropathy. (4003031)
1985
25
Uremic neuropathy: clinical and neurophysiological investigation of dialysis patients using different chemical membranes. (4065159)
1985
26
Evaluation of uremic neuropathy by visual (VEP) and brainstem auditory (BAEP) evoked potentials. (3837513)
1985
27
Thermal sensitivity in uremic neuropathy. (4003032)
1985
28
Control of uremic neuropathy by equilibrium peritoneal dialysis. (6329962)
1984
29
Experimental uremic neuropathy. Part 2. Sodium permeability decrease and inactivation in potential clamped nerve fibers. (6088705)
1984
30
Improvement of uremic neuropathy and hypogeusia by dialysate zinc supplementation: a double-blind study. (6330425)
1983
31
Uremic neuropathy: correlations between electroneurographic parameters and serum levels of parathyroid hormone and aluminum. (6293832)
1982
32
Progress of peripheral uremic neuropathy during continuous ambulatory peritoneal dialysis (CAPD). (6298985)
1982
33
Tibial nerve H-reflex and F-wave studies in patients with uremic neuropathy. (6252459)
1980
34
Detection of uremic neuropathy by reflex response latency. (6251176)
1980
35
Motor nerve conduction indicators in uremic neuropathy. (7356822)
1980
36
H-reflex latency in uremic neuropathy: correlation with NCV and clinical findings. (224838)
1979
37
Uremic neuropathy: evidence of middle molecule toxicity. (687020)
1978
38
Letter: Carbamazepine in uremic neuropathy. (176912)
1976
39
Electrophysiologic changes in uremic neuropathy after successful renal transplantation. (176611)
1976
40
Uremic neuropathy. III. Controlled study of restricted protein and fluid diet and infrequent hemodialysis versus conventional hemodialysis treatment. (171524)
1975
41
Uremic neuropathy. Monitoring of transketolase activity inhibition in a child. (4265477)
1973
42
Uremic neuropathy. (4328348)
1971
43
Transketolase inhibition as a mechanism in uremic neuropathy. (5164301)
1971
44
Effects of renal transplantation on uremic neuropathy. A clinical and electrophysiologic study. (4324615)
1971
45
Segmental demyelination secondary to axonal degeneration in uremic neuropathy. (4326086)
1971
46
Effect of hemodialysis on the inhibition of nervous tissue transketolase and on uremic neuropathy. (5158138)
1971
47
Recovery from uremic neuropathy. (4324616)
1971
48
Observations on plasma magnesium levels in patients with uremic neuropathy under treatment by periodic hemodialysis. (5466463)
1970
49
Uremic neuropathy. (4378313)
1967
50
Restless legs syndrome in uremic neuropathy. (4286316)
1966

Variations for Uremic Neuropathy

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Expression for genes affiliated with Uremic Neuropathy

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Search GEO for disease gene expression data for Uremic Neuropathy.

Pathways for genes affiliated with Uremic Neuropathy

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GO Terms for genes affiliated with Uremic Neuropathy

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Biological processes related to Uremic Neuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to cadmium ionGO:00466869.8B2M, PTH
2cellular calcium ion homeostasisGO:00068749.7PTH, XK

Molecular functions related to Uremic Neuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.5EPO, PTH

Sources for Uremic Neuropathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet