Aliases & Classifications for Uremic Pruritus

About this section
Sources:
51Orphanet, 65UMLS, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Uremic Pruritus:

Name: Uremic Pruritus 51 65

Characteristics:

Orphanet epidemiological data:

51
uremic pruritus:
Prevalence: 1-5/10000 (Europe)

Classifications:



External Ids:

Orphanet51 94059
UMLS via Orphanet66 C1262019
UMLS65 C1262019

Summaries for Uremic Pruritus

About this section
Wikipedia:68 Uremic pruritus (also known as uraemic pruritus or renal pruritus) is caused by chronic kidney failure... more...

MalaCards based summary: Uremic Pruritus is related to metabolic acidosis and bacterial exanthem, and has symptoms including cholestatic pruritus, implant site pruritus and uraemia odour. An important gene associated with Uremic Pruritus is IL2 (Interleukin 2), and among its related pathways are IL12 signaling mediated by STAT4 and Th2 Differentiation Pathway. Affiliated tissues include kidney, breast and prostate.

Related Diseases for Uremic Pruritus

About this section

Diseases related to Uremic Pruritus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 110)
idRelated DiseaseScoreTop Affiliating Genes
1metabolic acidosis10.5IL18, IL2
2bacterial exanthem10.5CRP, IL2
3cerebellar disease10.5IL18, IL2
4acute leukemia of ambiguous lineage10.5IL18, IL2
5labyrinthine unilateral reactive loss10.4CRP, IL18
6renal oncocytoma10.4IL18, IL2
7leukoplakia of penis10.4IL18, IL2
8hypoglycemic coma10.4CRP, IL18
9temporal arteritis10.3CRP, SLC17A5
10social phobia10.3CRP, SLC17A5
11leukomelanoderma mental redardation hypotrichosis10.3IL18, SLC17A5
12plasmacytoma10.2IL2, IL6
13parovarian cyst10.2IL2, IL6
14collagenous colitis10.2IL2, IL6
15critical illness polyneuropathy10.2IL2, IL6
16cold urticaria10.1CRP, IL6
17catamenial pneumothorax10.1CRP, IL6
18multicentric osteolysis nephropathy10.1CRP, IL6
19lujo hemorrhagic fever10.1CRP, IL6
20stomach cancer10.1CRP, IL6
21inflammatory leiomyosarcoma10.1CRP, IL6
22methemoglobinemia10.1CRP, IL6
23intestinal impaction10.1CRP, IL6
24ischemic optic neuropathy10.1CRP, IL6
25congenital dyserythropoietic anemia10.1CRP, IL6
26amusia10.1CRP, IL6
27cecum lymphoma10.1CRP, IL6
28congenital chloride diarrhea10.1CRP, IL6
29narcissistic personality disorder10.1CRP, IL6
30basilar artery occlusion10.1IL2, IL6
31scrotum squamous cell carcinoma10.1CRP, IL6
32heterophyiasis10.1CRP, IL6
33oral mucosa leukoplakia10.1CRP, IL6
34endocarditis10.1CRP, IL6
35partial circumpapillary choroid dystrophy10.1CRP, IL6
36neonatal diabetes mellitus10.1CRP, IL6
37aggressive digital papillary adenocarcinoma10.1CRP, IL6
38alcoholic gastritis10.1CRP, IL6
39hypopharynx cancer10.1CRP, IL6
40peritonitis10.1
41constant exophthalmos10.1CRP, IL6
42protein-energy malnutrition10.1CRP, IL6
43pyrimidine metabolic disorder10.1CRP, IL6
44monckeberg arteriosclerosis10.1IL18, IL6
45keratomalacia10.1CRP, IL6
46lateral sclerosis10.1CRP, IL6
47cutaneous paget's disease10.1CRP, IL6
48intraocular lymphoma10.1CRP, IL6
49acute gonococcal epididymo-orchitis10.1IL2, IL6
50bardet-biedl syndrome 810.1CRP, IL6

Graphical network of the top 20 diseases related to Uremic Pruritus:



Diseases related to uremic pruritus

Symptoms for Uremic Pruritus

About this section

UMLS symptoms related to Uremic Pruritus:


cholestatic pruritus, implant site pruritus, uraemia odour, vulvovaginal pruritus, application site pruritus, injection site pruritus, eyelids pruritus, generalized pruritus, pruritus of genital organs, pruritus

Drugs & Therapeutics for Uremic Pruritus

About this section

Drugs for Uremic Pruritus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 74)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Gabapentinapproved, investigationalPhase 426960142-96-33446
Synonyms:
1-(Aminomethyl)-cyclohexaneacetic acid
1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(aminomethyl)cyclohexyl]acetic acid
60142-96-3
AC-1485
AC1L1FYE
AC1Q53PH
AKOS000280865
Aclonium
Apo-Gabapentin
Apotex brand of gabapentin
Aventis brand of gabapentin
BB_SC-1512
BIDD:GT0656
BPBio1_000993
BRN 2359739
BSPBio_000901
C040029
C9H17NO2
CAS-60142-96-3
CCRIS 7210
CHEBI:188316
CHEBI:42797
CHEMBL940
CI 945
CI-945
CID3446
D00332
DB00996
DDS-2003
DM-1796
DM-5689
EINECS 262-076-3
EU-0100582
G-154
G0318
G154_SIGMA
GBN
GOE 2450
Gabapen
Gabapentin
Gabapentin (JAN/USAN/INN)
Gabapentin GR
Gabapentin Hexal
Gabapentin Kit
Gabapentin Stada
Gabapentin [USAN:INN:BAN]
Gabapentin-ratiopharm
Gabapentina
Gabapentine
Gabapentine [INN-French]
Gabapentino
Gabapentino [INN-Spanish]
Gabapentino [Spanish]
Gabapentinum
 
Gabapentinum [INN-Latin]
Gabapetin
Go 3450
Goe-3450
Gralise
Gralise Starter Pack
HMS1570N03
HMS2089J03
HSDB 7364
Hexal brand of gabapentin
I06-0677
L000733
LS-7194
Lopac-G-154
Lopac0_000582
MLS000069358
MolPort-000-883-862
NCGC00015466-01
NCGC00015466-02
NCGC00015466-06
NCGC00015466-09
NCGC00016891-01
NCGC00021545-02
NCGC00021545-04
NCGC00021545-05
NSC742194
Neurontin
Neurontin (TN)
Novo-Gabapentin
Novo-Gabapentine
Novopharm brand of gabapentin
PMS-Gabapentin
Parke Davis brand of gabapentin
Pfizer brand of gabapentin
Pharmascience brand of gabapentin
Prestwick0_000861
Prestwick1_000861
Prestwick2_000861
Prestwick3_000861
Prestwick_151
S2133_Selleck
SMR000058311
SPBio_002822
STK598009
Serada
Stadapharm brand of gabapentin
TL8003814
Tocris-0806
UNII-6CW7F3G59X
Vultin
Warner-Lambert brand of gabapentin
[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
gabapentin
gabapentin (Neurontin)
gabapentina
gabapentinium
ratiopharm brand of gabapentin
2
Benzyl alcoholapprovedPhase 423100-51-6244
Synonyms:
(Hydroxymethyl)benzene
(hydroxymethyl)benzene
.alpha.-hydroxytoluene
.alpha.-toluenol
Alcoholum benzylicum
Alcool benzylique
Alcoolbenzylique
Aromatic alcohol
Aromatic primary alcohol
Averteax
Bentalol
Benzal alcohol
Benzalalcohol
Benzalcohol
Benzenecarbinol
Benzenemethanol
Benzenmethanol
Benzoyl alcohol
Benzyl alcohol
Benzyl alkohol
Benzyl-alcohol
BenzylAlcohol
 
Benzylalkohol
Benzylic alcohol
Benzylicum
Caswell No. 081F
Enzylalcohol
Euxyl K 100
Hydroxymethylbenzene
Hydroxytoluene
Itch-x
MBN
Methanol benzene
Phenolcarbinol
Phenylcarbinol
Phenylcarbinolum
Phenylmethanol
Phenylmethyl alcohol
Sunmorl BK 20
TB 13G
Ulesfia
Zilactin Early Relief Cold Sore
a-Hydroxytoluene
a-Toluenol
alpha-Hydroxytoluene
alpha-Toluenol
3
Pregabalinapproved, illicit, investigationalPhase 4340148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
4
Histamine PhosphateapprovedPhase 490651-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
EINECS 200-118-4
 
H0147
Histamine Positive Skin Test Control
Histamine Positive skin test control
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
5
FexofenadineapprovedPhase 45883799-24-03348
Synonyms:
159389-12-5
2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid
2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid
4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
76815-58-2
83799-24-0
AC1L1FQB
Allegra
Allegra-D 12 Hour
Allegra-D 24 Hour
BRD-A73368467-003-02-8
BSPBio_003521
C06999
C32H39NO4
CHEBI:5050
CHEMBL914
CID3348
Carboxyterfenadine
D07958
DB00950
EU-0100488
F 9427
Fexofenadine
Fexofenadine (INN)
Fexofenadine Hydrochloride
Fexofenadine [INN:BAN]
Fexofenadine hydrochloride
Fexofendine
Fexofenodine Hydrochloride
HSDB 7486
 
KBio2_002449
KBio2_005017
KBio2_007585
KBio3_002742
KBioGR_000807
KBioSS_002456
L000869
LS-28827
Lopac0_000488
MDL 16455
MolPort-002-508-207
NCGC00015453-03
NCGC00015453-06
NCGC00092389-02
NCGC00092389-03
SPBio_001197
STK624102
STOCK6S-26154
Spectrum2_001179
Spectrum3_001921
Spectrum4_000204
Spectrum5_001474
Spectrum_001914
Telfast
Telfast (TN)
Terfenadine acid metabolite
Terfenadine carboxylate
Terfenadine-COOH
Terfenidine carboxylate, MDL 16455
UNII-E6582LOH6V
fexofenadine
6
Vitamin Eapproved, nutraceuticalPhase 437159-02-914985
Synonyms:
(+)-a-Tocopherol
(+)-alpha-Tocopherol
(+)-alpha-tocopherol
(+)-α-tocopherol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R,4'R,8'R)-a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
(2R,4'R,8'r)-alpha-tocopherol
(R,R,R)-a-Tocopherol
(R,R,R)-alpha-Tocopherol
(R,R,R)-alpha-tocopherol
(R,R,R)-α-tocopherol
5,7,8-Trimethyltocol
Amino-Opti-E
Aquasol E
D-alpha-Tocopherol
Daltose
Denamone
E-200 I.U. Softgels
 
E-Complex-600
E-Ferol
E-Vitamin succinate
Eprolin
Gordo-Vite E
Phytogermin
Phytogermine
RRR-alpha-tocopherol
RRR-alpha-tocopheryl
Tocopherol
Vitamin E
Vitamin Ea
Vitamin Plus E Softgells
Vitamin e
Vitec
a-D-Tocopherol
a-Tocopherol
alpha-Tocopherol
alpha-delta-Tocopherol
d-alpha-tocopherol
d-α-tocopherol
delta-alpha-Tocopherol
7
GlycerolexperimentalPhase 419156-81-5753
Synonyms:
1,2,3-Trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerine
Glyceritol
Glycerol
 
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
8calcium channel blockersPhase 41743
9AnalgesicsPhase 4, Phase 2, Phase 3, Phase 19358
10AnticonvulsantsPhase 42249
11Tranquilizing AgentsPhase 43597
12Polymethyl MethacrylatePhase 440
13Neurotransmitter AgentsPhase 414795
14Psychotropic DrugsPhase 45501
15Calcium, DietaryPhase 44678
16Anti-Anxiety AgentsPhase 41529
17Central Nervous System DepressantsPhase 4, Phase 2, Phase 3, Phase 110016
18Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 118510
19Vasodilator AgentsPhase 42926
20Protective AgentsPhase 45651
21TocopherolsPhase 4376
22AnestheticsPhase 47385
23Anesthetics, LocalPhase 42347
24Carbopol 940Phase 418
25PetrolatumPhase 484
26PramoxinePhase 45
27Phase 4
28Histamine H1 Antagonists, Non-SedatingPhase 4323
29Histamine AntagonistsPhase 4826
30Histamine H1 AntagonistsPhase 4688
31
histaminePhase 490675614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
32Anti-Allergic AgentsPhase 41312
33TocopherolNutraceuticalPhase 4376
34
Citric AcidnutraceuticalPhase 4100177-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
35CitrateNutraceuticalPhase 41001
36
NalbuphineapprovedPhase 2, Phase 3, Phase 12520594-83-65360630, 5311304
Synonyms:
(5alpha,6alpha)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol
17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol
20594-83-6
BIDD:GT0060
BPBio1_000150
BRD-K66404838-003-03-8
BSPBio_000136
C07251
CHEBI:7454
CHEMBL895
CID5311304
D08246
HMS2089I04
Intapan
 
Intapan (TN)
N-Cyclobutylmethyl-4,5alpha-epoxy-3,6alpha,14-morphinantriol
Nalbufina
Nalbuphin
Nalbuphine
Nalbuphine (INN)
Nalbuphine Hydrochloride
Nalbuphine hydrochloride
Nalbuphinum
Prestwick0_000118
Prestwick1_000118
Prestwick2_000118
Prestwick3_000118
SPBio_002075
nalbuphine
37Dermatologic AgentsPhase 34555
38NarcoticsPhase 2, Phase 3, Phase 12709
39EmollientsPhase 3121
40AntipruriticsPhase 2, Phase 3619
41Narcotic AntagonistsPhase 2, Phase 3, Phase 1814
42Analgesics, OpioidPhase 2, Phase 3, Phase 12304
43Contraceptives, OralPhase 2, Phase 33734
44Respiratory System AgentsPhase 23931
45Anti-Asthmatic AgentsPhase 22796
46Cromolyn SodiumPhase 216
47FumitoryNutraceuticalPhase 21
48Omega 3 Fatty AcidNutraceuticalPhase 1, Phase 2912
49OliveNutraceuticalPhase 1, Phase 2235
50
Montelukastapproved264158966-92-85281040
Synonyms:
(R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
(R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-[[[(1 R)-1-[3-[(1e)-2-(7-chloro-2-Quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
151767-02-1 (sodium)
158966-92-8
2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
AC1NQXXW
Apxi toxin
BIDD:GT0394
Brondilat
Brondilat (TN)
C07482
C35H36ClNO3S
CHEBI:50730
CHEMBL787
CID5281040
D08229
 
DB00471
HMS2089D07
HSDB 7582
LS-173539
MK 0476
MK-0476
Montair
Montelukast
Montelukast (INN)
Montelukast Sodium
Montelukast [INN:BAN]
Montelukast sodium
Montelukastum
Montélukast
Singulair
Singular
UNII-MHM278SD3E
montelukast
sodium 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate
{1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid

Interventional clinical trials:

(show all 26)
idNameStatusNCT IDPhase
1Uremic Pruritus, Cytokines and Polymethylmethacrylate Artificial KidneyCompletedNCT00442819Phase 4
2Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis PatientsActive, not recruitingNCT00693654Phase 4
3Efficacy of Pregabalin in the Management of Chronic Uremic PruritusNot yet recruitingNCT01073501Phase 4
4Pregabalin for the Treatment of Uremic PruritusNot yet recruitingNCT01852318Phase 4
5Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic PruritusCompletedNCT02143648Phase 2, Phase 3
6Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic PruritusCompletedNCT02143973Phase 2, Phase 3
7Efficacy, Local Tolerance and Patient Acceptability of a Moisturizing Emollient in Patients With Uremic XerosisCompletedNCT01084720Phase 3
8Combined Western and Traditional Chinese Medicine Daycare for CKD PatientsRecruitingNCT02545036Phase 3
9A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)Not yet recruitingNCT00793156Phase 3
10Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic PruritusCompletedNCT02229929Phase 2
11Evaluating the Effect of Cromolyn Sodium in Uremic PruritusCompletedNCT00745199Phase 2
12Evaluating the Effect of Fumaria Parviflora L. in Uremic PruritusCompletedNCT02671162Phase 2
13Treatment of Uremic Pruritus With PA101BActive, not recruitingNCT02696499Phase 2
14Treatment of Uremic Pruritus by Olive-omega 3 OintmentNot yet recruitingNCT01447693Phase 1, Phase 2
15Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving HemodialysisTerminatedNCT01660243Phase 2
16Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic PruritusCompletedNCT02373215Phase 1
17Evaluating the Effect of Senna in Uremic PruritusCompletedNCT02008864
18Montelukast for Treatment of Uremic PruritusCompletedNCT02559388
19The Effect of Phototherapy on Pruritus of Patients With Chronic Kidney DiseaseCompletedNCT00494975
20Pruritus in Patients With Chronic Kidney DiseaseCompletedNCT01727180
21Gabapentin for Prophylaxis Intrathecal Morphine-Induced PruritusCompletedNCT01236859
22Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing HemodialysisRecruitingNCT02432508
23Small-fiber Neuropathy in Chronic Kidney DiseaseRecruitingNCT01078857
24An Observational Study of Pruritus Amongst Hemodialysis PatientsActive, not recruitingNCT00715260
25Efficacy of Calmmax Cream in the Management of Chronic Uremic PruritusNot yet recruitingNCT02032537
26Gabapentin - A Solution to Uremic Pruritus?Not yet recruitingNCT00577967

Search NIH Clinical Center for Uremic Pruritus

Genetic Tests for Uremic Pruritus

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Anatomical Context for Uremic Pruritus

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MalaCards organs/tissues related to Uremic Pruritus:

33
Kidney, Breast, Prostate, Skin, Liver, Lung, Heart

Animal Models for Uremic Pruritus or affiliated genes

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Publications for Uremic Pruritus

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Articles related to Uremic Pruritus:

(show top 50)    (show all 116)
idTitleAuthorsYear
1
Comparison of Avena sativa, vinegar, and hydroxyzine for uremic pruritus of hemodialysis patients: a crossover randomized clinical trial. (26174460)
2015
2
Association of high-sensitive C-reactive protein and dialysis adequacy with uremic pruritus. (26354559)
2015
3
Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial. (26495017)
2015
4
Safety of pregabalin among hemodialysis patients suffering from uremic pruritus. (26702255)
2015
5
Is uremic pruritus still an important clinical problem in maintenance hemodialysis patients? (26616469)
2015
6
Role of Interleukin-2 in Uremic Pruritus Among Attendants of AL-Zahraa Hospital Dialysis Unit. (25814728)
2015
7
Quiz page August 2014: pruritus in a dialysis patient. Mycosis fungoides (folliculotropic variant) in a dialysis patient, with rare presentation of persistent generalized pruritus with characteristics of uremic pruritus without skin lesions. (25060007)
2014
8
Efficacy and Safety of Gabapentin for Uremic Pruritus and Restless Legs Syndrome in Conservatively Managed Patients With Chronic Kidney Disease. (25220049)
2014
9
Interleukin-31 is associated with uremic pruritus in patients receiving hemodialysis. (25270263)
2014
10
Uremic pruritus. (24402092)
2014
11
The effect of ergocalciferol on uremic pruritus severity: a randomized controlled trial. (23453391)
2013
12
Uremic pruritus, dialysis adequacy, and metabolic profiles in hemodialysis patients: a prospective 5-year cohort study. (23940749)
2013
13
Longitudinal predictors of uremic pruritus. (24209894)
2013
14
Effective treatment of uremic pruritus and acquired perforating dermatosis with amitriptyline. (23425115)
2013
15
Effect of acupressure on patients in Turkey receiving hemodialysis treatment for uremic pruritus. (23981400)
2013
16
Effect of sertraline on uremic pruritus improvement in ESRD patients. (22973512)
2012
17
Baby oil therapy for uremic pruritus in haemodialysis patients. (22093006)
2012
18
Acupuncture for treating uremic pruritus in patients with end-stage renal disease: a systematic review. (21796811)
2010
19
A longitudinal study of uremic pruritus in hemodialysis patients. (20558560)
2010
20
A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients. (18821119)
2009
21
Gabapentin and uremic pruritus in hemodialysis patients. (19212903)
2009
22
Nalfurafine hydrochloride: a new drug for the treatment of uremic pruritus in hemodialysis patients. (19584962)
2009
23
Nicotinamide as a potential novel addition to the anti-uremic pruritus weaponry. (19237824)
2009
24
Characteristics of uremic pruritus in hemodialysis patients: data from a single center. (18794819)
2008
25
Uremic pruritus, cytokines, and polymethylmethacrylate artificial kidney. (18422797)
2008
26
Effect of oral granisetron in uremic pruritus. (17675729)
2007
27
Clinical characteristics of uremic pruritus in patients undergoing haemodialysis. (16499798)
2006
28
Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. (16797388)
2006
29
Efficacy and safety of a new kappa-opioid receptor agonist for the treatment of uremic pruritus. (16932462)
2006
30
An epidemiology study of patients with uremic pruritus. (16836494)
2006
31
Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients. (16672924)
2006
32
A comparative study on the effects of naltrexone and loratadine on uremic pruritus. (15178915)
2004
33
Uremic pruritus: still an important clinical problem. (15523377)
2004
34
Uremic pruritus: a clinical study of maintenance hemodialysis patients. (12432992)
2002
35
Management of uremic pruritus. (10833778)
2000
36
Naltrexone does not relieve uremic pruritus: results of a randomized, double-blind, placebo-controlled crossover study. (10703675)
2000
37
Ondansetron therapy for uremic pruritus in hemodialysis patients. (10793015)
2000
38
Is aluminum toxicity responsible for uremic pruritus in chronic hemodialysis patients? (9031270)
1997
39
Potentially toxic self-treatment of uremic pruritus with topical pyrethroid insecticides. (8997483)
1997
40
Uremic pruritus in CAPD patients. (9358524)
1997
41
L-carnitine does not alleviate uremic pruritus in hemodialysis patients. (9069470)
1997
42
Uremic pruritus. (8791145)
1996
43
Uremic pruritus. (8679435)
1995
44
Uremic pruritus: a review. (1738396)
1992
45
Uremic pruritus in patients on hemodialysis or continuous ambulatory peritoneal dialysis (CAPD). The role of plasma histamine and skin mast cells. (1699691)
1990
46
Uremic pruritus. Clinical and experimental studies. (2773616)
1989
47
Uremic pruritus treated with ultraviolet light. (7365958)
1980
48
Uremic pruritus: a review. (380932)
1979
49
Ultraviolet phototherapy of uremic pruritus. Long-term results and possible mechanism of action. (464448)
1979
50
Relief of uremic pruritus with ultraviolet phototherapy. (865585)
1977

Variations for Uremic Pruritus

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Expression for genes affiliated with Uremic Pruritus

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Search GEO for disease gene expression data for Uremic Pruritus.

Pathways for genes affiliated with Uremic Pruritus

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GO Terms for genes affiliated with Uremic Pruritus

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Biological processes related to Uremic Pruritus according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of tissue remodelingGO:003410510.3IL18, IL2
2positive regulation of interleukin-17 productionGO:003274010.2IL18, IL2
3natural killer cell activationGO:003010110.2IL18, IL2
4positive regulation of interferon-gamma productionGO:003272910.0IL18, IL2
5positive regulation of inflammatory responseGO:00507299.9IL18, IL2
6defense response to Gram-positive bacteriumGO:00508309.7CRP, IL6
7response to insulinGO:00328689.6IL6, OPRK1
8inflammatory responseGO:00069548.9CRP, IL18, IL6
9positive regulation of gene expressionGO:00106288.8CRP, IL18, IL6
10immune responseGO:00069558.2IL18, IL2, IL6, OPRK1

Sources for Uremic Pruritus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet