Aliases & Classifications for Ureteral Obstruction

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Aliases & Descriptions for Ureteral Obstruction:

Name: Ureteral Obstruction 8 10 44


External Ids:

Disease Ontology8 DOID:5199
SNOMED-CT56 197807001
ICD9CM27 593.4

Summaries for Ureteral Obstruction

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MalaCards based summary: Ureteral Obstruction is related to renal fibrosis and colitis. An important gene associated with Ureteral Obstruction is BMP7 (bone morphogenetic protein 7), and among its related pathways are TGF-beta Signaling Pathway and SMAD Signaling Network. The compounds enalapril and irbesartan have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and endothelial, and related mouse phenotypes are immune system and renal/urinary system.

Related Diseases for Ureteral Obstruction

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Graphical network of the top 20 diseases related to Ureteral Obstruction:



Diseases related to ureteral obstruction

Symptoms for Ureteral Obstruction

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Drugs & Therapeutics for Ureteral Obstruction

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Drug clinical trials:

Search ClinicalTrials for Ureteral Obstruction

Search NIH Clinical Center for Ureteral Obstruction

Genetic Tests for Ureteral Obstruction

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Anatomical Context for Ureteral Obstruction

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MalaCards organs/tissues related to Ureteral Obstruction:

31
Kidney, Bone, Endothelial, Bone marrow, Colon, Prostate, Monocytes, Liver, Myeloid, Lymph node, Cortex, Smooth muscle, Breast, Uterus

Animal Models for Ureteral Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Ureteral Obstruction:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.6AGTR1, BMP7, CLU, TGFB1, PTGS1
2MP:00053677.5AGTR1, BMP7, CLU, TGFB1, PTGS1
3MP:00053857.3PTGS1, TGFB1, CLU, BMP7, AGTR1

Publications for Ureteral Obstruction

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Articles related to Ureteral Obstruction:

(show top 50)    (show all 589)
idTitleAuthorsYear
1
Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats. (25707520)
2015
2
Percutaneous ureteral stent placement for the treatment of a benign ureteral obstruction in a Sumatran tiger (Panthera tigris sumatrae). (25653150)
2015
3
KS370G, a caffeamide derivative, attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice. (25620133)
2015
4
Retrospective study of the perioperative management and complications of ureteral obstruction in 37 cats. (25732861)
2015
5
Combination Therapy with Losartan and I+-Tocopherol in Acute Ureteral Obstruction-Induced Renal Excretory Dysfunction and Acidification Defect. (25031488)
2014
6
Effect of unilateral ureteral obstruction and anti-angiotensin II treatment on renal tubule cell apoptosis and interstitial fibrosis in rats. (25144992)
2014
7
ROS dependence of cyclooxygenase-2 induction in rats subjected to unilateral ureteral obstruction. (24226522)
2014
8
Oleanolic acid attenuates renal fibrosis in mice with unilateral ureteral obstruction via facilitating nuclear translocation of Nrf2. (24393202)
2014
9
Metallic Ureteral Stents in Malignant Ureteral Obstruction: Clinical Factors Predicting Stent Failure. (24397490)
2014
10
The effect of carvedilol on serum and tissue oxidative stress parameters in partial ureteral obstruction induced rat model. (23257252)
2013
11
Ulinastatin inhibits unilateral ureteral obstruction-induced renal interstitial fibrosis in rats via transforming growth factor I^ (TGF-I^)/Smad signalling pathways. (23318600)
2013
12
Five-year experience with metallic stents for chronic ureteral obstruction. (23485505)
2013
13
The protective effects of metyrosine, lacidipine, clonidine, and moxonidine on kidney damage induced by unilateral ureteral obstruction in rats. (22202971)
2012
14
Commentary to 'Ureteral obstruction following injection of dextranomer/hyaluronic acid copolymer: an infrequent but relevant complication'. (22056308)
2012
15
Dermatan sulfate reduces monocyte chemoattractant protein 1 and TGF-I^ production, as well as macrophage recruitment and myofibroblast accumulation in mice with unilateral ureteral obstruction. (21833458)
2011
16
Vitamin E ameliorates renal fibrosis in ureteral obstruction: role of maintaining BMP-7 during epithelial-to-mesenchymal transition. (22619901)
2011
17
Renal parenchymal fibrosis and atrophy are not correlated with upper tract dilatation: long-term study of partial unilateral ureteral obstruction in neonatal mice. (21527217)
2011
18
Editorial comment on: Ureteral obstruction: is the full metallic double-pigtail stent the way to go? (19232818)
2010
19
Postpartum ovarian vein thrombosis presenting as ureteral obstruction. (22767678)
2010
20
Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: a P-selectin-mediated event? (20861075)
2010
21
Noninvasive assessment of acute ureteral obstruction with diffusion-weighted MR imaging: a prospective study. (19567650)
2009
22
Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression. (19530942)
2009
23
Atorvastatin ameliorates tubulointerstitial fibrosis and protects renal function in chronic partial ureteral obstruction cases. (19692013)
2009
24
Endoscopic management of a ureteral obstruction caused by endometriosis: a case report. (19502140)
2009
25
Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor. (18555228)
2008
26
Activation of Erk1/2 and Akt following unilateral ureteral obstruction. (18449171)
2008
27
Upregulation and function of GADD45gamma in unilateral ureteral obstruction. (18354378)
2008
28
Robotically assisted excision of ovarian vein for intermittent ureteral obstruction. (18435891)
2008
29
Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction. (18094035)
2008
30
Re: Borin JF, Melamud O, Clayman RV. Initial experience with full-length metal stent to relieve malignant ureteral obstruction. J Endourol 2006;20:300-304. (18401884)
2008
31
Malignant extrinsic ureteral obstruction: a survey of urologists and medical oncologists regarding treatment patterns and preferences. (18372019)
2008
32
Acute renal papillary necrosis with complete bilateral ureteral obstruction in a child. (17382173)
2007
33
Myeloid sarcoma presenting with acute renal failure and bilateral ureteral obstruction: a case report and review of the literature. (17700206)
2007
34
Scintigraphic demonstration of urine extravasation secondary to acute ureteral obstruction: a case report and some considerations about acute ureteral obstruction. (17619724)
2006
35
Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction. (17003824)
2006
36
Apoptosis of circulating lymphocyte in rats with unilateral ureteral obstruction: role of angiotensin II. (16221096)
2005
37
An unusual cause of ureteral obstruction in a renal transplant recipient: ureteric aspergilloma. (15964354)
2005
38
The effect of partial unilateral ureteral obstruction release and allopurinol on the renal malondialdehyde and glutathione levels. (16351656)
2005
39
Activation of ERK in renal fibrosis after unilateral ureteral obstruction: modulation by antioxidants. (15698432)
2005
40
Images in clinical medicine. Ureteral obstruction in pregnancy. (15483272)
2004
41
Percutaneous nephrostomy versus indwelling ureteral stents in the management of extrinsic ureteral obstruction in advanced malignancies: are there differences? (15533473)
2004
42
Diagnosis of ureteral obstruction in patients with compromised renal function: the role of noninvasive imaging modalities. (15126809)
2004
43
Effects of mycophenolate mofetil on renal interstitial fibrosis after Unilateral ureteral obstruction in rats. (14526430)
2003
44
Ureteral obstruction and reconstruction in pelvic actinomycosis. (12559308)
2003
45
Extensive retroperitoneal fibrosis with duodenal and ureteral obstruction associated with giant inflammatory aneurysm of the abdominal aorta. (14677743)
2003
46
Late post-reimplantation ureteral obstruction during pregnancy: a transient phenomenon? (12913713)
2003
47
Recoverability of renal function after relief of acute complete ureteral obstruction: clinical prospective study of the role of renal resistive index. (11927300)
2002
48
Anuria due to bilateral ureteral obstruction by Aspergillus flavus in an adult male. (11927329)
2002
49
Lower pole ureteral obstruction secondary to fecal impaction in an 8-year-old girl. (11763494)
2001
50
Xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. (6653472)
1983

Variations for Ureteral Obstruction

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Expression for genes affiliated with Ureteral Obstruction

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Search GEO for disease gene expression data for Ureteral Obstruction.

Pathways for genes affiliated with Ureteral Obstruction

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Compounds for genes affiliated with Ureteral Obstruction

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Compounds related to Ureteral Obstruction according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1enalapril44 50 1111.9AGTR1, BMP7
2irbesartan44 28 50 1112.9AGTR1, PTGS1
3carvedilol44 50 28 1112.8AGTR1, PTGS1
48-isoprostane449.8PTGS1, AGTR1
5aminoguanidine44 28 1111.7CLU, AGTR1
6pirfenidone44 6010.6TGFB1, BMP7
7alginate449.6BMP7, TGFB1
8benazepril44 50 1111.6AGTR1, TGFB1
9gm-csf44 2810.5TGFB1, PTGS1
10ramipril44 1110.5TGFB1, AGTR1
11perindopril44 50 1111.5TGFB1, AGTR1
12ns 39844 6010.5TGFB1, PTGS1
13acetaminophen44 1 50 24 1113.5PTGS1, AGTR1
14ang ii449.4TGFB1, AGTR1
15thromboxane a244 2410.4PTGS1, AGTR1
16methacholine44 50 1111.4AGTR1, TGFB1
17deoxyribonucleic acid449.4BMP7, CLU, AGTR1
18clonidine44 50 28 1112.3AGTR1, TGFB1
19ethanol44 50 24 1112.3BMP7, CLU, AGTR1
20losartan44 50 28 1112.2AGTR1, TGFB1
214-hydroxytamoxifen449.2CLU, TGFB1
22tgf beta1449.1AGTR1, TGFB1, BMP7
23candesartan44 50 28 1112.1AGTR1, TGFB1, PTGS1
24sodium nitroprusside449.1PTGS1, AGTR1, TGFB1
25rosiglitazone28 44 50 24 1113.1PTGS1, AGTR1, TGFB1
26heparin44 28 24 1112.1CLU, BMP7, AGTR1
27pge2449.1BMP7, TGFB1, PTGS1
28aspirin44 50 28 2412.1PTGS1, TGFB1, AGTR1
29agarose449.0BMP7, TGFB1, CLU
30calcitriol44 60 24 1112.0CLU, BMP7, TGFB1
311,25 dihydroxy vitamin d3449.0TGFB1, CLU
32ribonucleic acid449.0TGFB1, CLU, BMP7
33h2o2449.0AGTR1, CLU, PTGS1
34etoposide44 50 60 1112.0TGFB1, CLU, PTGS1
35creatinine448.9AGTR1, TGFB1, BMP7
36paraffin448.9CLU, TGFB1, PTGS1
37thymidine44 249.9CLU, TGFB1, BMP7
38butyrate448.9TGFB1, DCXR, CLU
39tamoxifen44 50 28 1111.9AGTR1, CLU, TGFB1
40lactate448.9PTGS1, TGFB1, CLU
41oxygen44 249.9AGTR1, BMP7, PTGS1, CLU
42cisplatin44 50 60 1111.8TGFB1, AGTR1, CLU
43kainate44 289.7TGFB1, CLU
44actinomycin d448.5AGTR1, CLU, TGFB1, PTGS1
45vitamin d448.1AGTR1, BMP7, CLU, PTGS1, TGFB1
46cycloheximide448.1CLU, BMP7, AGTR1, TGFB1, PTGS1
47dexamethasone44 50 28 1111.1AGTR1, BMP7, CLU, TGFB1, PTGS1
48vegf448.1TGFB1, AGTR1, PTGS1, CLU, BMP7
49estrogen448.1AGTR1, CLU, TGFB1, PTGS1, BMP7
50serine448.1BMP7, AGTR1, TGFB1, CLU, PTGS1

GO Terms for genes affiliated with Ureteral Obstruction

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Cellular components related to Ureteral Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1microvillusGO:00059029.0TGFB1, DCXR
2blood microparticleGO:00725629.0CLU, TGFB1
3platelet alpha granule lumenGO:00310938.7CLU, TGFB1

Biological processes related to Ureteral Obstruction according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of peptidyl-threonine phosphorylationGO:00108009.5BMP7, TGFB1
2response to vitamin DGO:00332809.5BMP7, TGFB1
3positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.5TGFB1, BMP7
4positive regulation of bone mineralizationGO:00305019.4BMP7, TGFB1
5epithelial to mesenchymal transitionGO:00018379.4TGFB1, BMP7
6positive regulation of cellular protein metabolic processGO:00322709.4AGTR1, TGFB1
7regulation of cell proliferationGO:00421279.4AGTR1, PTGS1
8ureteric bud developmentGO:00016579.4BMP7, TGFB1
9negative regulation of cell cycleGO:00457869.4BMP7, TGFB1
10response to estradiolGO:00323559.3BMP7, TGFB1
11lipid metabolic processGO:00066299.1CLU, PTGS1
12platelet degranulationGO:00025769.0TGFB1, CLU
13positive regulation of NF-kappaB transcription factor activityGO:00510929.0CLU, TGFB1
14positive regulation of apoptotic processGO:00430658.8BMP7, CLU, TGFB1

Sources for Ureteral Obstruction

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet