MCID: URT014
MIFTS: 43

Ureterolithiasis malady

Nephrological diseases category

Summaries for Ureterolithiasis

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66Wikipedia, 34MalaCards
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Wikipedia:66 A bladder stone (also called a vesical calculus or cystolith) is a stone found in the urinary bladder.... more...

MalaCards: Ureterolithiasis, also known as calculus of ureter, is related to nephrolithiasis and embryoma. An important gene associated with Ureterolithiasis is AKAP5 (A kinase (PRKA) anchor protein 5), and among its related pathways are Adrenergic signaling in cardiomyocytes and AMPK Enzyme Complex Pathway. The compounds (+)-adrenaline and 5-methylurapidil have been mentioned in the context of this disorder. Affiliated tissues include kidney and adrenal gland, and related mouse phenotypes are behavior/neurological and renal/urinary system.

Aliases & Classifications for Ureterolithiasis

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9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 36MeSH, 28ICD9CM, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

ureterolithiasis 9 11 63
calculus of ureter 9
ureteric calculus 9
ureteral calculi 63
ureteric stone 9


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Disease Ontology9 DOID:14146
MeSH36 D053039
SNOMED-CT59 31054009, 95573009
ICD9CM28 592.1
ICD1026 N20.1

Related Diseases for Ureterolithiasis

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18GeneCards, 19GeneDecks
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Diseases related to Ureterolithiasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 31)
idRelated DiseaseScoreTop Affiliating Genes
1nephrolithiasis10.5
2embryoma10.2
3angiomyolipoma10.2
4transitional cell carcinoma10.2
5ureterocele10.1
6nephrogenic adenoma10.1
7ankylosis10.1
8end stage renal failure10.1
9vesicoureteral reflux10.1
10small cell carcinoma10.1
11osteogenesis imperfecta10.1
12azoospermia10.1
13adenoma10.1
14cystitis10.1
15prostatitis10.1
16purpura10.1
17pyelonephritis10.1
18systemic mastocytosis10.1
19uremia10.1
20fibromuscular dysplasia10.1
21mastocytosis10.1
22anuria10.0
23perinephritis10.0
24ureteral obstruction10.0
25cystinuria10.0
26appendicitis10.0
27hydronephrosis10.0
28endometriosis10.0
29adenine phosphoribosyltransferase deficiency10.0
30blindness10.0
31renal dysplasia10.0

Graphical network of the top 20 diseases related to Ureterolithiasis:



Diseases related to ureterolithiasis

Symptoms for Ureterolithiasis

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Drugs & Therapeutics for Ureterolithiasis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Ureterolithiasis

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Genetic Tests for Ureterolithiasis

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Anatomical Context for Ureterolithiasis

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34MalaCards
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MalaCards organs/tissues related to Ureterolithiasis:

34
Kidney, Adrenal gland

Animal Models for Ureterolithiasis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Ureterolithiasis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.2AKAP5, ADRA1B, APRT, ADRA1A
2MP:00053677.9APRT, ADRA1B, ADRA1A, SLC12A3
3MP:00053767.2SLC12A3, APRT, ADRA1B, ADRA1A, AKAP5

Publications for Ureterolithiasis

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53PubMed
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Articles related to Ureterolithiasis:

(show top 50)    (show all 75)
idTitleAuthorsYear
1
Terpene compound drug as medical expulsive therapy for ureterolithiasis: a meta-analysis. (23503876)
2013
2
Bladder bulge: unifying old and new sonographic bladder wall abnormalities in ureterolithiasis. (23358632)
2012
3
Bedside renal ultrasound in the evaluation of suspected ureterolithiasis. (21185667)
2012
4
Unusual presentation of bilateral ureteroceles with ureterolithiasis in a patient after robotic prostatectomy. (22546412)
2012
5
Health related quality of life in ureteral stone patients: post-ureterolithiasis. (21461963)
2011
6
Ureterolithiasis in children. (21585171)
2011
7
The effect of alpha-blockade in emergency department patients with ureterolithiasis. (19217243)
2010
8
The sensitivity of transabdominal ultrasound in the diagnosis of ureterolithiasis. (21203595)
2010
9
A case of calcified ureteritis cystica: an indiscernible condition from ureterolithiasis. (19655701)
2009
10
Conventional and reduced radiation dose of 16-MDCT for detection of nephrolithiasis and ureterolithiasis. (18094305)
2008
11
Type IV ureteral triplication associated with ipsilateral ureterocele with ureterolithiasis and contralateral duplication with an ectopic ureteral orifice. (19138195)
2008
12
Comparison between ultrasound and noncontrast helical computed tomography for identification of acute ureterolithiasis in a teaching hospital setting. (17625708)
2007
13
Ureteroscopical treatment of ureterolithiasis in childhood. Our experience. (16752883)
2006
14
Medical-expulsive therapy for distal ureterolithiasis: randomized prospective study on role of corticosteroids used in combination with tamsulosin-simplified treatment regimen and health-related quality of life. (16230122)
2005
15
Electro-acupuncture treatment for the upper segment ureterolithiasis under B-ultrasonography. (15889513)
2005
16
Unenhanced helical CT scan for ureterolithiasis. (15321049)
2004
17
Diagnostic value of attenuation measurements of the kidney on unenhanced helical CT of obstructive ureterolithiasis. (15100127)
2004
18
Unenhanced helical CT of ureterolithiasis: incidence of secondary urinary tract findings. (15058632)
2004
19
Helical CT for nephrolithiasis and ureterolithiasis: comparison of conventional and reduced radiation-dose techniques. (14526095)
2003
20
Acute ureterolithiasis: incidence of secondary signs on unenhanced helical CT and influence on patient management. (14654033)
2003
21
Pneumatic lithotripsy for ureterolithiasis: clinical analysis of 512 cases. (12865242)
2003
22
Ureterolithiasis: classical and atypical findings on unenhanced helical computed tomography. (15290602)
2002
23
Acute flank pain: comparison of unenhanced helical CT and ultrasonography in detecting causes other than ureterolithiasis. (15290574)
2002
24
Management of calcium ureterolithiasis in a French lop rabbit. (11791774)
2001
25
The role of renal scintigraphy and unenhanced helical computerized tomography in patients with ureterolithiasis. (10805118)
2000
26
Diagnosis and management of acute ureterolithiasis: CT is truth. (10882237)
2000
27
Extracorporeal shockwave lithotripsy for ureterolithiasis in patients with urinary bilharziasis: efficacy and variables that influence treatment outcome. (10671781)
2000
28
Pearls and pitfalls in the diagnosis of ureterolithiasis with unenhanced helical CT. (10715342)
2000
29
Chronic renal failure associated with nephrolithiasis, ureterolithiasis, and renal dysplasia in a 2-year-old quarter horse gelding. (10463829)
1999
30
Partial adenine phosphoribosyltransferase deficiency detected by ureterolithiasis. (9510404)
1998
31
Ureterolithiasis: can clinical outcome be predicted with unenhanced helical CT? (9646798)
1998
32
Unenhanced helical CT of ureterolithiasis: value of the tissue rim sign. (9124157)
1997
33
Spiral computed tomography for diagnosing ureterolithiasis. (8933326)
1996
34
Dry extracorporeal shock wave lithotripsy for treatment of ureterolithiasis and nephrolithiasis in a dog. (7649772)
1995
35
Ureterolithiasis in a Renal Transplant Patient Secondary to Encrustation about a Suture Line. (18583741)
1995
36
Extracorporeal shock wave lithotripsy for treatment of ureterolithiasis in patients with cystinuria. (8149169)
1993
37
Rowatinex for the treatment of ureterolithiasis. (1431192)
1992
38
Obstructive nephrolithiasis and ureterolithiasis associated with chronic renal failure in horses: eight cases (1981-1987). (2200763)
1990
39
Metoclopramide (Primperan) in the treatment of ureterolithiasis. A prospective double-blind study of metoclopramide compared with morphatropin on ureteral colic. (1691882)
1990
40
Paravaginal tumor: ureterolithiasis in an ectopic ureter. (2520817)
1989
41
Percutaneous nephrostomy in short-term management of ureterolithiasis and renal dysfunction in a filly. (2674092)
1989
42
Ureterolithiasis and creatine kinase. (2729807)
1989
43
Importance of No-Spa and Probon combination in the conservative treatment of ureterolithiasis patients. (6571196)
1984
44
Idiopathic ureterolithiasis in a renal transplant patient. (789922)
1976
45
Mucosal folding in upper urinary pathways following ureterolithiasis. (983762)
1976
46
Evaluation of renal function in ureterolithiasis and nephrolithiasis on the basis of radioactive renography. (5964895)
1966
47
Intraperitoneal rupture of the ureter: a complication of ureterolithiasis following ureterointestinal anastomosis. (5332654)
1966
48
The results of expectant treatment of ureterolithiasis: follow-up study of kidney function and recurrences. (13605497)
1958
49
The use of octin in ureterolithiasis, a case report. (21017382)
1946
50
CO-EXISTENT NEPHROLITHIASIS AND URETEROLITHIASIS ON OPPOSITE SIDES. (17865070)
1924

Variations for Ureterolithiasis

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Expression for genes affiliated with Ureterolithiasis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ureterolithiasis

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Pathways for genes affiliated with Ureterolithiasis

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Sources:
51PathCards, 31KEGG, 54QIAGEN, 56Reactome, 39NCBI BioSystems Database, 52PharmGKB, 61Thomson Reuters
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Pathways related to Ureterolithiasis according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1ADRA1A, ADRA1B
2
Show member pathways
9.1ADRA1A, ADRA1B
39.1ADRA1B, ADRA1A
4
Show member pathways
9.1ADRA1A, ADRA1B
5
Show member pathways
9.1ADRA1A, ADRA1B
6
Show member pathways
Calcium Regulation in the Cardiac Cell39
9.1ADRA1A, ADRA1B
7
Show member pathways
9.1ADRA1A, ADRA1B
8
Show member pathways
9.1ADRA1B, ADRA1A
9
Show member pathways
9.1ADRA1A, ADRA1B
109.1ADRA1B, ADRA1A
119.1ADRA1A, ADRA1B
12
Show member pathways
Development Activation of ERK by Alpha 1 adrenergic receptors61
9.1ADRA1A, ADRA1B
13
Show member pathways
8.7AKAP5, ADRA1A, ADRA1B
14
Show member pathways
8.7AKAP5, ADRA1A, ADRA1B

Compounds for genes affiliated with Ureterolithiasis

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Sources:
30IUPHAR, 62Tocris Bioscience, 46Novoseek, 12DrugBank, 52PharmGKB, 25HMDB
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Compounds related to Ureterolithiasis according to GeneCards/GeneDecks:

(show top 50)    (show all 63)
idCompoundScoreTop Affiliating Genes
1(+)-adrenaline309.6ADRA1B, ADRA1A
25-methylurapidil309.6ADRA1A, ADRA1B
3ro-70-0004309.6ADRA1A, ADRA1B
4a-119637309.6ADRA1A, ADRA1B
5indoramin309.6ADRA1A, ADRA1B
6a-123189309.6ADRA1A, ADRA1B
7(+)-cyclazosin309.6ADRA1A, ADRA1B
8ns-49309.6ADRA1A, ADRA1B
9rec 15/2739309.6ADRA1B, ADRA1A
10a 61603 hydrobromide629.6ADRA1A, ADRA1B
11cirazoline hydrochloride629.6ADRA1A, ADRA1B
12rs 100329 hydrochloride629.6ADRA1A, ADRA1B
13(r)-(-)-phenylephrine hydrochloride629.6ADRA1A, ADRA1B
14rs 17053 hydrochloride629.5ADRA1A, ADRA1B
15(+)-niguldipine309.5ADRA1A, ADRA1B
16[125i]heat309.5ADRA1A, ADRA1B
17[125i]be-2254309.5ADRA1A, ADRA1B
18bmy-7378309.5ADRA1B, ADRA1A
19nan 190309.5ADRA1A, ADRA1B
20(-)-adrenaline309.5ADRA1A, ADRA1B
21wb 4101309.5ADRA1B, ADRA1A
22labetalol46 1210.5ADRA1B, ADRA1A
23midodrine46 1210.5ADRA1B, ADRA1A
24alfuzosin46 1210.5ADRA1B, ADRA1A
25(-)-noradrenaline309.5ADRA1B, ADRA1A
26silodosin30 1210.5ADRA1B, ADRA1A
27dextroamphetamine30 1210.5ADRA1B, ADRA1A
28methoxamine46 30 1211.5ADRA1A, ADRA1B
29spiroxatrine46 3010.5ADRA1B, ADRA1A
30terazosin46 1210.5ADRA1B, ADRA1A
31tamsulosin46 30 1211.5ADRA1B, ADRA1A
32oxymetazoline46 30 1211.5ADRA1B, ADRA1A
33spiperone46 3010.5ADRA1A, ADRA1B
34ritanserin46 3010.4ADRA1A, ADRA1B
35trimipramine46 52 1211.4ADRA1B, ADRA1A
36sertindole30 46 1211.4ADRA1B, ADRA1A
37phentolamine46 30 1211.4ADRA1B, ADRA1A
38cyproheptadine46 30 1211.4ADRA1B, ADRA1A
39nefazodone46 52 1211.4ADRA1B, ADRA1A
40promazine46 1210.4ADRA1A, ADRA1B
41mianserin46 30 1211.4ADRA1B, ADRA1A
42thioridazine30 46 52 1212.3ADRA1B, ADRA1A
43ergotamine30 46 1211.3ADRA1B, ADRA1A
44paliperidone46 1210.3ADRA1B, ADRA1A
45pergolide46 30 1211.2ADRA1B, ADRA1A
46ketanserin46 3010.2ADRA1B, ADRA1A
47doxazosin46 1210.1ADRA1B, ADRA1A
48aripiprazole30 46 52 25 1213.1ADRA1A, ADRA1B
49doxepin46 30 52 1212.0ADRA1A, ADRA1B
50prazosin46 30 52 1211.8ADRA1A, ADRA1B

GO Terms for genes affiliated with Ureterolithiasis

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17Gene Ontology
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Cellular components related to Ureterolithiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear membraneGO:0319658.8ADRA1A, ADRA1B
2integral component of plasma membraneGO:0058878.4SLC12A3, ADRA1A, ADRA1B
3plasma membraneGO:0058868.1SLC12A3, AKAP5, ADRA1A, ADRA1B

Biological processes related to Ureterolithiasis according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of the force of heart contraction by epinephrine-norepinephrineGO:0019979.3ADRA1A, ADRA1B
2positive regulation of heart rate by epinephrine-norepinephrineGO:0019969.3ADRA1A, ADRA1B
3adrenergic receptor signaling pathwayGO:0718759.2ADRA1A, ADRA1B
4organ growthGO:0352659.2ADRA1A, ADRA1B
5adult heart developmentGO:0075129.1ADRA1B, ADRA1A
6cell-cell signalingGO:0072679.1ADRA1A, ADRA1B
7cell growthGO:0160499.0ADRA1A, ADRA1B
8positive regulation of MAPK cascadeGO:0434108.8ADRA1A, ADRA1B

Molecular functions related to Ureterolithiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alpha1-adrenergic receptor activityGO:0049379.1ADRA1A, ADRA1B

Products for genes affiliated with Ureterolithiasis

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Sources for Ureterolithiasis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet