MCID: URT014
MIFTS: 36

Ureterolithiasis malady

Categories: Nephrological diseases

Aliases & Classifications for Ureterolithiasis

Aliases & Descriptions for Ureterolithiasis:

Name: Ureterolithiasis 12 42 14 69
Calculus of Ureter 12
Ureteric Calculus 12
Ureteral Calculi 69
Ureteric Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14146
ICD9CM 35 592.1
MeSH 42 D053039
NCIt 47 C114696
SNOMED-CT 64 31054009 95573009
ICD10 33 N20.1
UMLS 69 C0041952

Summaries for Ureterolithiasis

MalaCards based summary : Ureterolithiasis, also known as calculus of ureter, is related to nephrolithiasis and hydronephrosis. An important gene associated with Ureterolithiasis is APRT (Adenine Phosphoribosyltransferase), and among its related pathways/superpathways are Calcium signaling pathway and Salivary secretion. The drugs Tamsulosin and Alfuzosin have been mentioned in the context of this disorder. Affiliated tissues include kidney and adrenal gland, and related phenotypes are behavior/neurological and renal/urinary system

Wikipedia : 71 Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone)... more...

Related Diseases for Ureterolithiasis

Graphical network of the top 20 diseases related to Ureterolithiasis:



Diseases related to Ureterolithiasis

Symptoms & Phenotypes for Ureterolithiasis

MGI Mouse Phenotypes related to Ureterolithiasis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.35 ADRA1A AKAP5 APBB1 APRT CHRM3
2 renal/urinary system MP:0005367 8.92 ADRA1A APRT CHRM3 SLC12A3

Drugs & Therapeutics for Ureterolithiasis

Drugs for Ureterolithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 111)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamsulosin Approved, Investigational Phase 4,Phase 3,Phase 2 106133-20-4 129211
2
Alfuzosin Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 81403-80-7 2092
3
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
4
Morphine Approved, Investigational Phase 4 57-27-2 5288826
5
Ketoprofen Approved, Vet_approved Phase 4 22071-15-4 3825
6
Silodosin Approved Phase 4,Phase 3,Phase 2 160970-54-7
7
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
8
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
9
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
10
Desflurane Approved Phase 4 57041-67-5 42113
11
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
12
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
13
Mirabegron Approved Phase 4,Phase 2 223673-61-8
14 Adrenergic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
15 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
16 Adrenergic alpha-Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
17 Adrenergic Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
18 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Early Phase 1
19 Antihypertensive Agents Phase 4,Phase 3
20 calcium channel blockers Phase 4,Phase 3
21 Calcium, Dietary Phase 4,Phase 3
22 Naftopidil Phase 4,Phase 3 57149-07-2
23 Platelet Aggregation Inhibitors Phase 4,Phase 3
24 Analgesics Phase 4,Phase 3
25 Analgesics, Non-Narcotic Phase 4,Phase 3
26 Analgesics, Opioid Phase 4
27 Anti-Inflammatory Agents Phase 4,Phase 3
28 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
29 Antirheumatic Agents Phase 4,Phase 3
30 Central Nervous System Depressants Phase 4
31 Cyclooxygenase Inhibitors Phase 4
32 Ketorolac Tromethamine Phase 4
33 Narcotics Phase 4
34 Nefopam Phase 4
35 Peripheral Nervous System Agents Phase 4,Phase 3
36 Anesthetics Phase 4
37 Vasodilator Agents Phase 4,Phase 3
38 Antipyretics Phase 4
39 Pharmaceutical Solutions Phase 4,Phase 1,Phase 2
40 Cholinergic Agents Phase 4
41 Cholinergic Antagonists Phase 4
42 Muscarinic Antagonists Phase 4
43 Solifenacin succinate Phase 4 242478-38-2
44 Anesthetics, General Phase 4
45 Anesthetics, Inhalation Phase 4
46 Acetaminophen, hydrocodone drug combination Phase 4
47 Adrenergic Agonists Phase 4,Phase 2
48 Adrenergic beta-3 Receptor Agonists Phase 4,Phase 2
49 Adrenergic beta-Agonists Phase 4,Phase 2
50 Phosphodiesterase 5 Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 112)
id Name Status NCT ID Phase
1 Efficacy of Tamsulosin Oral-controlled Absorption System (OCAS) in the Treatment of Distal Ureteral Stones Unknown status NCT01167062 Phase 4
2 The Use of Medical-Expulsive Therapy With Alfuzocine xl 10mg x1/d for Distal Ureterolithiasis.a Randomized Prospective Study Unknown status NCT00489112 Phase 4
3 The Efficacy of Alpha-blockers for Expulsion of Distal Ureteral Stones Unknown status NCT00451061 Phase 4
4 Naftopidil 75mg for Improving Clearance of Urinary Stones Unknown status NCT02011737 Phase 4
5 Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic Unknown status NCT01543165 Phase 4
6 Quality of Life in Patients With Double Loop Ureteral Stent (JJ Silicone Hydrogel Study) Unknown status NCT02489656 Phase 4
7 Nefopam and Morphine Consumption in the Treatment of Ureteral Calculi Completed NCT00639574 Phase 4
8 Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones Completed NCT01533389 Phase 4
9 Tamsulosin for Urolithiasis in the Emergency Dept Completed NCT00382265 Phase 4
10 Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management Completed NCT02187614 Phase 4
11 Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms Completed NCT01381120 Phase 4
12 Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females Completed NCT01310582 Phase 4
13 Treatment of Upper Ureteric Stones Recruiting NCT02469766 Phase 4
14 Ureteral Stent-related Pain and Mirabegron (SPAM) Trial Recruiting NCT02095665 Phase 4
15 Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) as Medical Expulsive Therapy in Distal Ureteral Stones Active, not recruiting NCT02519153 Phase 4
16 Silodosin Versus Tamsulosin for Treatment of Ureteral Stones Terminated NCT02369744 Phase 4
17 Use of a Ureteral Access Sheath During Ureteroscopy and Its Effect on Stone Free Rate Terminated NCT00199524 Phase 4
18 Celecoxib (Celebrex) in the Management of Acute Renal Colic Withdrawn NCT00304317 Phase 4
19 Alfuzosin for Medical Expulsion Therapy of Ureteral Stones Unknown status NCT00713739 Phase 3
20 Extracorporeal Shock Wave Lithotriptor Indicated for Fragmenting Urinary Stones in the Kidney Unknown status NCT00959153 Phase 3
21 Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Completed NCT00177086 Phase 3
22 Evaluation of Tamsulosin in the Treatment of Ureteral Stones Completed NCT00151567 Phase 3
23 Medical Expulsive Therapy for Ureter Stone Using Naftopidil Completed NCT01952314 Phase 3
24 The Effect of Naftopidil for the Double-J Stent Discomfort Completed NCT01959074 Phase 3
25 Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm. Terminated NCT02090439 Phase 3
26 Use of Alfuzosin in Stone Treatment With ESWL Withdrawn NCT00388271 Phase 3
27 Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy Withdrawn NCT01560091 Phase 3
28 Comparing Patients After ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin Unknown status NCT00478998 Phase 2
29 Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy Unknown status NCT00409227 Phase 2
30 Study of Silodosin to Facilitate Passage of Urinary Stones Completed NCT01144949 Phase 2
31 A Dose-finding Study of Silodosin in Patients With Urinary Calculi Completed NCT01539265 Phase 2
32 Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation Completed NCT00250406 Phase 2
33 Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones Completed NCT00857090 Phase 1, Phase 2
34 Mirabegron as Medical Expulsive Therapy (MET) for Ureteral Stones and Ureteral Stent Pain Not yet recruiting NCT02744430 Phase 2
35 Contrast-enhanced Ultrasound Versus CT Scan for Kidney Stone Patient Management Not yet recruiting NCT03058614 Phase 2
36 Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy Completed NCT02032316 Phase 1
37 Pharmacokinetic and Safety Study of OMS201 in Subjects Undergoing Ureteroscopic Treatment for Removal of Urinary Tract-Located Stones Completed NCT00599664 Phase 1
38 Silent Ureteral Stone: Impact on Renal Function and Kidney Anatomy Unknown status NCT01884870
39 Comparative Treatment Study in Patients With Lower Ureteral Stones Unknown status NCT00397397 Early Phase 1
40 Shockwave Lithotripsy (SWL) Under Selective, General Anesthesia. Unknown status NCT01008267
41 Intraureteral Lidocaine for Post-Ureteroscopy Pain Unknown status NCT01450566
42 Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy Unknown status NCT02279927
43 Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria Unknown status NCT02139059
44 A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members Unknown status NCT00994188
45 A Prospective Comparison Between Ureteral Stent and Nephrostomy Tube for an Urgent Drainage of Obstructed Kidney Unknown status NCT00739284
46 Antibiotic Prophylaxis When Removing Ureteric Stent After Stone Surgery Unknown status NCT01768364
47 Suspension of Mechanical Ventilation in Ureteroscopic Lithotripsy Under General Anesthesia Unknown status NCT01835600
48 The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients Completed NCT00600405
49 Study on 'The Use of Non-contrast Helical Computerized Tomogram in Predicting Treatment Outcomes of Upper Ureteric Stone by Extracorporeal Shock Wave Lithotripsy Using the Sonolith 4000+ Lithotripter' Completed NCT00517205
50 Medical Expulsive Therapy of Single Distal Ureteral Stones Completed NCT00831701

Search NIH Clinical Center for Ureterolithiasis

Cochrane evidence based reviews: ureterolithiasis

Genetic Tests for Ureterolithiasis

Anatomical Context for Ureterolithiasis

MalaCards organs/tissues related to Ureterolithiasis:

39
Kidney, Adrenal Gland

Publications for Ureterolithiasis

Articles related to Ureterolithiasis:

(show top 50) (show all 88)
id Title Authors Year
1
Spontaneous proximal ureteric rupture secondary to ureterolithiasis. ( 28069871 )
2017
2
Medical Expulsive Therapy for Ureterolithiasis: The EAU Recommendations in 2016. ( 27506951 )
2016
3
Comparison of prone vs. supineA unenhanced CT imaging in patients with clinically suspected ureterolithiasis. ( 27670877 )
2016
4
Beyond ureterolithiasis: gamut of abnormalities affecting the ureter. ( 27317212 )
2016
5
Is hydronephrosis on ultrasound predictive of ureterolithiasis in patients with renal colic? ( 27154825 )
2016
6
Clinical relevance of seasonal changes in the prevalence of ureterolithiasis in the diagnosis of renal colic. ( 27314408 )
2016
7
Management of Ureterolithiasis in a Patient with Crossed Unfused Renal Ectopia. ( 27403369 )
2016
8
The use of alpha-1 adrenergic blockers in children with distal ureterolithiasis: a systematic review and meta-analysis. ( 26717117 )
2015
9
Long-term Adverse Effects of Extracorporeal Shock-wave Lithotripsy for Nephrolithiasis and Ureterolithiasis: A Systematic Review. ( 25917723 )
2015
10
Tamsulosin for treatment of unilateral distal ureterolithiasis: a systematic review and meta-analysis. ( 24852587 )
2014
11
Tamsulosin for treatment of unilateral distal ureterolithiasis: a systematic review and meta-analysis. ( 23870675 )
2013
12
Re: terpene compound drug as medical expulsive therapy for ureterolithiasis: a meta-analysis. ( 23421365 )
2013
13
Anuria and abdominal pain induced by ceftriaxone-associated ureterolithiasis in adults. ( 23180444 )
2013
14
Indwelling double pigtail ureteral stent combined or not with surgery for feline ureterolithiasis: complications and outcome in 15 cases. ( 24305471 )
2013
15
Terpene compound drug as medical expulsive therapy for ureterolithiasis: a meta-analysis. ( 23503876 )
2013
16
Pyeloduodenal fistula due to proximal ureterolithiasis and its successful conservative management. ( 24051966 )
2013
17
Bladder bulge: unifying old and new sonographic bladder wall abnormalities in ureterolithiasis. ( 23358632 )
2012
18
Bedside renal ultrasound in the evaluation of suspected ureterolithiasis. ( 21185667 )
2012
19
Synchronous obstructive ureterolithiasis and acute appendicitis. ( 24960802 )
2012
20
Unusual presentation of bilateral ureteroceles with ureterolithiasis in a patient after robotic prostatectomy. ( 22546412 )
2012
21
Endoscopic holmium laser treatment for ureterolithiasis. ( 24578918 )
2012
22
Ureterolithiasis in children. ( 21585171 )
2011
23
Health related quality of life in ureteral stone patients: post-ureterolithiasis. ( 21461963 )
2011
24
The sensitivity of transabdominal ultrasound in the diagnosis of ureterolithiasis. ( 21203595 )
2010
25
The effect of alpha-blockade in emergency department patients with ureterolithiasis. ( 19217243 )
2010
26
Acute onset of renal colic from bilateral ureterolithiasis: a case report. ( 19829794 )
2009
27
A case of calcified ureteritis cystica: an indiscernible condition from ureterolithiasis. ( 19655701 )
2009
28
The utility of unenhanced helical CT in assessing the frequency of ureterolithiasis in Saudi patients. ( 18246228 )
2008
29
Conventional and reduced radiation dose of 16-MDCT for detection of nephrolithiasis and ureterolithiasis. ( 18094305 )
2008
30
Type IV ureteral triplication associated with ipsilateral ureterocele with ureterolithiasis and contralateral duplication with an ectopic ureteral orifice. ( 19138195 )
2008
31
Cost-effectiveness analysis (CEA) of intravenous urography (IVU) and unenhanced multidetector computed tomography (MDCT) for initial investigation of suspected acute ureterolithiasis. ( 18300151 )
2008
32
Usefulness of urinalysis in following patients with distal ureterolithiasis. ( 18578655 )
2008
33
Comparison between ultrasound and noncontrast helical computed tomography for identification of acute ureterolithiasis in a teaching hospital setting. ( 17625708 )
2007
34
Ureteroscopical treatment of ureterolithiasis in childhood. Our experience. ( 16752883 )
2006
35
Electro-acupuncture treatment for the upper segment ureterolithiasis under B-ultrasonography. ( 15889513 )
2005
36
Medical-expulsive therapy for distal ureterolithiasis: randomized prospective study on role of corticosteroids used in combination with tamsulosin-simplified treatment regimen and health-related quality of life. ( 16230122 )
2005
37
Diagnostic value of attenuation measurements of the kidney on unenhanced helical CT of obstructive ureterolithiasis. ( 15100127 )
2004
38
Unenhanced helical CT scan for ureterolithiasis. ( 15321049 )
2004
39
Unenhanced helical CT of ureterolithiasis: incidence of secondary urinary tract findings. ( 15058632 )
2004
40
Ureterolithiasis after Cohen re-implantation--case report. ( 15070415 )
2004
41
Helical CT for nephrolithiasis and ureterolithiasis: comparison of conventional and reduced radiation-dose techniques. ( 14526095 )
2003
42
Pneumatic lithotripsy for ureterolithiasis: clinical analysis of 512 cases. ( 12865242 )
2003
43
Acute ureterolithiasis: incidence of secondary signs on unenhanced helical CT and influence on patient management. ( 14654033 )
2003
44
Acute flank pain: comparison of unenhanced helical CT and ultrasonography in detecting causes other than ureterolithiasis. ( 15290574 )
2002
45
Speedy elimination of ureterolithiasis in lower part of ureters with the alpha 1-blocker--Tamsulosin. ( 12549635 )
2002
46
Ureterolithiasis: classical and atypical findings on unenhanced helical computed tomography. ( 15290602 )
2002
47
Management of calcium ureterolithiasis in a French lop rabbit. ( 11791774 )
2001
48
Diagnosis and management of acute ureterolithiasis: CT is truth. ( 10882237 )
2000
49
Extracorporeal shockwave lithotripsy for ureterolithiasis in patients with urinary bilharziasis: efficacy and variables that influence treatment outcome. ( 10671781 )
2000
50
The role of renal scintigraphy and unenhanced helical computerized tomography in patients with ureterolithiasis. ( 10805118 )
2000

Variations for Ureterolithiasis

Expression for Ureterolithiasis

Search GEO for disease gene expression data for Ureterolithiasis.

Pathways for Ureterolithiasis

Pathways related to Ureterolithiasis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.43 ADRA1A CHRM3
2
Show member pathways
11.17 ADRA1A CHRM3
3
Show member pathways
10.68 ADRA1A CHRM3

GO Terms for Ureterolithiasis

Biological processes related to Ureterolithiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.56 ADRA1A AKAP5 APBB1 CHRM3
2 regulation of vasoconstriction GO:0019229 9.16 ADRA1A CHRM3
3 positive regulation of smooth muscle contraction GO:0045987 8.96 ADRA1A CHRM3
4 smooth muscle contraction GO:0006939 8.62 ADRA1A CHRM3

Sources for Ureterolithiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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