MCID: URT032
MIFTS: 27

Urethra Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Urethra Adenocarcinoma

MalaCards integrated aliases for Urethra Adenocarcinoma:

Name: Urethra Adenocarcinoma 12 14
Adenocarcinoma of the Urethra 12
Urethral Adenocarcinoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4910
NCIt 46 C6167
UMLS 69 C1336885

Summaries for Urethra Adenocarcinoma

Disease Ontology : 12 An urethra cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Urethra Adenocarcinoma, also known as adenocarcinoma of the urethra, is related to urethra clear cell adenocarcinoma and prostatic acinar adenocarcinoma. An important gene associated with Urethra Adenocarcinoma is FNDC3B (Fibronectin Type III Domain Containing 3B), and among its related pathways/superpathways are Pathways in cancer and Endometrial cancer. The drugs nivolumab and Antibodies have been mentioned in the context of this disorder. Related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Urethra Adenocarcinoma

Graphical network of the top 20 diseases related to Urethra Adenocarcinoma:



Diseases related to Urethra Adenocarcinoma

Symptoms & Phenotypes for Urethra Adenocarcinoma

MGI Mouse Phenotypes related to Urethra Adenocarcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 PAX8 SMAD4 UPK3A ALK AMACR APP
2 mortality/aging MP:0010768 9.23 PAX8 SMAD4 ALK AMACR APP ARID2

Drugs & Therapeutics for Urethra Adenocarcinoma

Drugs for Urethra Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
nivolumab Approved Phase 2 946414-94-4
2 Antibodies Phase 2
3 Antibodies, Monoclonal Phase 2
4 Immunoglobulins Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Urethra Adenocarcinoma

Genetic Tests for Urethra Adenocarcinoma

Anatomical Context for Urethra Adenocarcinoma

Publications for Urethra Adenocarcinoma

Articles related to Urethra Adenocarcinoma:

# Title Authors Year
1
Female Urethra Adenocarcinoma. ( 29113768 )
2017
2
Female urethra adenocarcinoma: report of two cases and bibliographic review. ( 25306993 )
2014

Variations for Urethra Adenocarcinoma

Expression for Urethra Adenocarcinoma

Search GEO for disease gene expression data for Urethra Adenocarcinoma.

Pathways for Urethra Adenocarcinoma

GO Terms for Urethra Adenocarcinoma

Biological processes related to Urethra Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of apoptotic process GO:0042981 9.54 ALK ATM PAX8
2 branching involved in ureteric bud morphogenesis GO:0001658 9.32 PAX8 SMAD4
3 ovarian follicle development GO:0001541 9.26 ATM SMAD4
4 neuron apoptotic process GO:0051402 9.16 APP ATM
5 female gonad development GO:0008585 8.96 ATM SMAD4
6 kidney development GO:0001822 8.8 PAX8 SMAD4 UPK3A

Sources for Urethra Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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