MCID: URT011
MIFTS: 31

Urethral Calculus malady

Categories: Nephrological diseases

Aliases & Classifications for Urethral Calculus

Aliases & Descriptions for Urethral Calculus:

Name: Urethral Calculus 12 14
Calculus in Urethra 69
Urethral Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9589
ICD10 33 N21.1
ICD9CM 35 594.2
NCIt 47 C26995
SNOMED-CT 64 155880008 20342001
UMLS 69 C0162301

Summaries for Urethral Calculus

MalaCards based summary : Urethral Calculus, also known as calculus in urethra, is related to urethritis and prostatitis. An important gene associated with Urethral Calculus is PLIN1 (Perilipin 1), and among its related pathways/superpathways are Androgen receptor signaling pathway and Platelet Aggregation Inhibitor Pathway, Pharmacodynamics. The drugs Anesthetics and Central Nervous System Depressants have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and pancreas, and related phenotype is behavior/neurological.

Wikipedia : 71 Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone)... more...

Related Diseases for Urethral Calculus

Graphical network of the top 20 diseases related to Urethral Calculus:



Diseases related to Urethral Calculus

Symptoms & Phenotypes for Urethral Calculus

MGI Mouse Phenotypes related to Urethral Calculus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.1 PLIN1 USF1 F2 FLNA ITGA2 MCU

Drugs & Therapeutics for Urethral Calculus

Drugs for Urethral Calculus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics
2 Central Nervous System Depressants

Interventional clinical trials:


id Name Status NCT ID Phase
1 Shock Wave Lithotripsy Versus Visual Cystolitholapaxy in The Management of Patients Presenting With Calcular Acute Urinary Retention: A Randomized Controlled Trial. Recruiting NCT02594631 Phase 4
2 The Usefulness of Flexible Cystoscopy for Preventing Double-J Stent Malposition After Laparoscopic Ureterolithotomy Completed NCT03150446
3 Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function Completed NCT00790231
4 Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy Completed NCT00984100
5 "Dusting" Versus "Basketing" - Treatment Of Intrarenal Stones Active, not recruiting NCT01619735
6 Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic Not yet recruiting NCT02878148
7 The Effect of Transvaginal vs. Conventional Laparoscopic Cholecystectomy on the Postoperative Course Terminated NCT01552421

Search NIH Clinical Center for Urethral Calculus

Genetic Tests for Urethral Calculus

Anatomical Context for Urethral Calculus

MalaCards organs/tissues related to Urethral Calculus:

39
Kidney, Prostate, Pancreas

Publications for Urethral Calculus

Articles related to Urethral Calculus:

(show top 50) (show all 57)
id Title Authors Year
1
Giant anterior urethral calculus associated with urethrocutaneous fistula in an elderly man. ( 27671903 )
2016
2
Urethral calculus originating from ureterocele and causing urinary retention. ( 26498566 )
2015
3
A Giant Urethral Calculus. ( 26982670 )
2014
4
Impacted anterior urethral calculus complicated by a stone-containing diverticulum in an elderly man: outcome of transurethral lithotripsy without resection of the diverticulum. ( 24267119 )
2013
5
Large anterior urethral calculus presented as scrotal mass with urethrocutaneous fistula. ( 24068377 )
2013
6
A giant dumbbell shaped vesico-prostatic urethral calculus: a case report and review of literature. ( 23762742 )
2013
7
Urethral calculus. ( 19939603 )
2012
8
Obstructing urethral calculus in a woman revealed to be the cause of chronic pelvic pain. ( 22407234 )
2012
9
Giant urethral calculus. ( 24950400 )
2011
10
Unusual giant prostatic urethral calculus. ( 22091328 )
2010
11
Acute urinary retention secondary to a urethral calculus in a bladder-drained kidney pancreas transplant patient - a metallic clip nidus. ( 19215698 )
2009
12
Impacted urethral calculus discovered on pelvic ultrasound: a case report. ( 19947057 )
2009
13
Giant urethral calculus in a 6-year-old girl. ( 19013415 )
2008
14
Giant prostatic urethral calculus associated with urethrocutaneous fistula. ( 16771746 )
2006
15
Transrectal voiding sonourethrography for diagnosis of a prostatic urethral calculus. ( 17060434 )
2006
16
Laser lithotripsy of a urethral calculus via ischial urethrotomy in a steer. ( 11549094 )
2001
17
Urethral calculus extraction using a penile ring block anesthetic. ( 9800901 )
1998
18
Giant urethral calculus: a rare cause of acute urinary retention. ( 8969990 )
1996
19
Giant urethral calculus. ( 7899907 )
1994
20
Pediatric bladder outlet obstruction due to urethral calculus. Case report and review of the literature. ( 8309762 )
1993
21
Use of transperineal sonography to locate an obstructing urethral calculus. ( 8416631 )
1993
22
Formation of a urethral calculus around an unusual foreign body. ( 8402033 )
1993
23
Struvite urethral calculus in a three-month-old thoroughbred colt. ( 1643877 )
1992
24
Re: Giant posterior urethral calculus. A. Bolukbasi and B. Gumus. Br. J. Urol., 65, 301-302, 1990. ( 2249137 )
1990
25
Giant posterior urethral calculus. ( 2337755 )
1990
26
Expulsion of urethral calculus following intermittent closure of suprapubic catheter. ( 2804575 )
1989
27
Giant urethral calculus. ( 2611634 )
1989
28
Sonographic diagnosis of an obstructing urethral calculus. ( 3054147 )
1988
29
Spontaneous passage of large urethral calculus. ( 3942026 )
1986
30
Giant anterior urethral calculus associated with hypospadias and congenital meatal stenosis. ( 3971094 )
1985
31
Ultrasonic detection of urethral calculus. ( 3904910 )
1985
32
Foreign body urethral calculus 9 years after traumatic perforation of the rectum. ( 4005511 )
1985
33
Giant urethral calculus in a nine-year-old girl. ( 3971095 )
1985
34
Impacted membranous urethral calculus. ( 6520412 )
1984
35
Giant prostatic urethral calculus. (A case report). ( 6864581 )
1983
36
Submucosal urethral calculus secondary to foxtail awn migration in a dog. ( 6345496 )
1983
37
Spontaneous delivery of giant urethral calculus. ( 6674358 )
1983
38
Case profile: radiolucent urethral calculus with hemostatic clip nidus. ( 7064268 )
1982
39
Giant urethral calculus: a case report. ( 561198 )
1977
40
Giant urethral calculus: a case report. ( 940221 )
1976
41
Prostatic urethral calculus. ( 5016075 )
1972
42
Urethral calculus in a six-week-old puppy. ( 6070657 )
1967
43
Impacted urethral calculus. An analysis of 42 cases. ( 5945414 )
1966
44
Surgical management of an unusual urethral calculus. ( 13980456 )
1963
45
Impacted vesico-urethral calculus: a case report. ( 13900169 )
1961
46
Giant urethral calculus: a case report. ( 13564579 )
1958
47
Urethral calculus: its roentgen evaluation. ( 13134511 )
1954
48
Urethral calculus in the male, with particular reference to giant primary stones. ( 15399440 )
1950
49
Large urethral calculus; case report. ( 18141445 )
1949
50
Giant urethral calculus. ( 18921040 )
1948

Variations for Urethral Calculus

Expression for Urethral Calculus

Search GEO for disease gene expression data for Urethral Calculus.

Pathways for Urethral Calculus

Pathways related to Urethral Calculus according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.11 FLNA KLK3
2 10.66 F2 ITGA2
3 9.95 F2 KLK3

GO Terms for Urethral Calculus

Biological processes related to Urethral Calculus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 glucose homeostasis GO:0042593 9.26 MCU USF1
2 establishment of protein localization GO:0045184 9.16 FLNA ITGA2
3 positive regulation of collagen biosynthetic process GO:0032967 8.96 F2 ITGA2
4 negative regulation of fibrinolysis GO:0051918 8.62 F2 USF1

Sources for Urethral Calculus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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