MCID: URT016
MIFTS: 30

Urethral Diverticulum malady

Categories: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

Aliases & Descriptions for Urethral Diverticulum:

Name: Urethral Diverticulum 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9341
ICD10 33 N36.1
ICD9CM 35 599.2
NCIt 47 C39861
SNOMED-CT 64 90531003
UMLS 69 C0152443

Summaries for Urethral Diverticulum

MalaCards based summary : Urethral Diverticulum is related to urethritis and adenocarcinoma. An important gene associated with Urethral Diverticulum is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways/superpathways is Adhesion. Affiliated tissues include prostate, testes and skin, and related phenotype is cellular.

Wikipedia : 71 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

Related Diseases for Urethral Diverticulum

Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
id Related Disease Score Top Affiliating Genes
1 urethritis 10.9
2 adenocarcinoma 10.3
3 cervix endometriosis 10.3 AMACR UPK3A
4 ovary rhabdomyosarcoma 10.3 KLK3 NKX3-1
5 brachyolmia 10.3 AMACR PVR
6 mucinous adenofibroma 10.2 AMACR WT1
7 alveolar echinococcosis 10.2 KIDINS220 UPK3A
8 colon signet ring adenocarcinoma 10.2 AMACR KLK3
9 exotropia 10.2 PAX8 WT1
10 progressive multifocal leukoencephalopathy 10.2 AMACR WT1
11 rectal disease 10.2 KLK3 PVR
12 hypochondriasis 10.2 KIDINS220 KLK3
13 thyroid crisis 10.2 KLK3 PVR
14 vaginitis 10.2
15 adenoma 10.2
16 gallbladder cancer 10.2 AMACR PAX8
17 epithelioid cell melanoma 10.2 KLK3 PKDREJ
18 iris spindle cell melanoma 10.2 AMACR KLK3 UPK3A
19 nephrogenic adenoma 10.2
20 ischemic fasciitis 10.2 KLK3 MCU
21 splenic infarction 10.2 AMACR KLK3 UPK3A
22 adult medulloblastoma 10.1 AMACR KLK3 NKX3-1
23 superficial urinary bladder cancer 10.1 AMACR KLK3 PAX8
24 perivascular epithelioid cell tumor 10.1 PAX8 UPK3A WT1
25 mucinous tubular and spindle renal cell carcinoma 10.1 AMACR PAX8
26 bardet-biedl syndrome 10.1 AMACR KLK3 NKX3-1
27 rhinitis 10.1 AMACR KLK3 PAX8
28 clear cell adenocarcinoma 10.1
29 klinefelter's syndrome 10.1 KLK3 PAX8
30 uterine corpus epithelioid leiomyoma 10.1 F3 KLK3
31 microglandular adenosis 10.1 KRT7 UPK3A
32 cranial nerve disease 10.1 KLK3 PAX8
33 kimura disease 10.1 KRT7 PAX8
34 meninges hemangiopericytoma 10.1 PAX8 WT1
35 gastrointestinal neuroendocrine tumor 10.1 KRT7 PAX8
36 prostate small cell carcinoma 10.1 KLK3 UPK3A
37 brain injury 10.1 KLK3 MCU UPK3A
38 vulva squamous cell carcinoma 10.1 KRT7 UPK3A
39 generalized eruptive keratoacanthoma 10.1 AMACR KRT7
40 klatskin's tumor 10.1 KRT7 UPK3A
41 steroid-induced glaucoma - borderline 10.1 KLK3 KRT7
42 angiolipomatosis, familial 10.1 KRT7 UPK3A
43 renal pelvis carcinoma 10.0 AMACR KLK3 PAX8 UPK3A
44 myotonia congenita 10.0 KRT7 UPK3A
45 thymus gland disease 10.0 AMACR KLK3 PAX8 UPK3A
46 prostate lymphoma 10.0 KLK3 KRT7
47 medullomyoblastoma 10.0 KLK3 KRT7
48 prostatitis 10.0
49 squamous cell carcinoma 10.0
50 peripheral nervous system ganglioneuroblastoma 9.9 AMACR KRT7 WT1

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to Urethral Diverticulum

Symptoms & Phenotypes for Urethral Diverticulum

MGI Mouse Phenotypes related to Urethral Diverticulum:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.23 F3 FUT4 KIDINS220 KRT7 MCU NKX3-1

Drugs & Therapeutics for Urethral Diverticulum

Interventional clinical trials:


id Name Status NCT ID Phase
1 A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty Recruiting NCT02634619

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

Anatomical Context for Urethral Diverticulum

MalaCards organs/tissues related to Urethral Diverticulum:

39
Prostate, Testes, Skin, Kidney, Colon

Publications for Urethral Diverticulum

Articles related to Urethral Diverticulum:

(show top 50) (show all 301)
id Title Authors Year
1
Anastomotic Urethroplasty for an Obstructing Calculus Within a Bulbar Urethral Diverticulum and Urethral Stricture. ( 27981035 )
2017
2
The Prostate in Female? Clear Cell Adenocarcinoma in a Female Urethral Diverticulum. ( 27789300 )
2017
3
Female Urethral Diverticulum: Presentation, Diagnosis, and Predictors of Outcomes After Surgery. ( 27636213 )
2016
4
Acute Urinary Retention in a Female Following Bladder Tumor Resection Due To a Stone in a Urethral Diverticulum. ( 27085569 )
2016
5
Urethral Diverticulum in Women: Retrospective Case Series. ( 26924907 )
2016
6
Long-term outcomes after the excision of horseshoe urethral diverticulum. ( 26670574 )
2016
7
Anterior urethral diverticulum: A rare presentation. ( 27833294 )
2016
8
Female urethral diverticulum containing a urothelial carcinoma. ( 28057968 )
2016
9
Male urethral diverticulum uncommon entity: Our experience. ( 28057997 )
2016
10
Preoperative 3D and 4D-CT imaging using 640-Multislice CT (640-MSCT) in diagnosis of female urethral diverticulum. ( 27803968 )
2016
11
Congenital urethral diverticulum with infertility in an adult man and review of the literature. ( 27822441 )
2016
12
Nephrogenic adenoma arising in a complex circumferential urethral diverticulum of a female patient with a history of childhood neuroblastoma and chemotherapy. ( 27324755 )
2016
13
Acquired male urethral diverticulum: a rare entity treated in a one-stage procedure. ( 27895077 )
2016
14
Surgical treatment of an acquired posterior urethral diverticulum with cystoscopy assisted robotic technique. ( 27440231 )
2016
15
Excision of urethral diverticulum in a 24 year old woman. ( 25624583 )
2015
16
Urethral diverticulum: a potential hazard of penile clamp application for male urinary incontinence. ( 25858949 )
2015
17
Female Urethral Diverticulum: Current Diagnosis and Management. ( 26267225 )
2015
18
Female urethral diverticulum containing a giant calculus: a CARE-compliant case report. ( 25997056 )
2015
19
Congenital anterior urethral diverticulum: A case report. ( 26628815 )
2015
20
Urethral diverticulum in the female: a meta-analysis of modern series. ( 26545036 )
2015
21
Primary squamous cell carcinoma of the urethral diverticulum mimicking prostate cancer: Case report and review of the literature. ( 26029309 )
2015
22
Minimally invasive surgical approach to treat posterior urethral diverticulum. ( 25834967 )
2015
23
Congenital anterior urethral diverticulum: antenatal diagnosis with subsequent neonatal endoscopic management. ( 25704997 )
2015
24
Urethral Diverticulum Masquerading as Anterior Vaginal Wall Cyst: A Diagnostic Dilemma. ( 26557574 )
2015
25
Urinary retention in an infant caused by a posterior urethral diverticulum lithiasis following surgery for anorectal malformation. ( 24493407 )
2014
26
Simple vs complex urethral diverticulum: presentation and outcomes. ( 25432847 )
2014
27
Female urethral diverticulum: cases report and literature. ( 24528809 )
2014
28
Urethroscopic holmium: YAG laser ablation for acquired posterior urethral diverticulum after repair of anorectal malformations. ( 25062769 )
2014
29
Scrotal pop off in a congenital anterior urethral diverticulum. ( 24928476 )
2014
30
Incidence of female urethral diverticulum: a population-based analysis and literature review. ( 23857063 )
2014
31
Congenital duplication of the urethra with urethral diverticulum: a case report. ( 25254101 )
2014
32
Urethral Diverticulum After Midurethral Sling Erosion, Excision, and Subsequent Management. ( 25185624 )
2014
33
Nephrogenic adenoma in a urethral diverticulum. ( 25185615 )
2014
34
Congenital anterior urethral diverticulum. ( 26328174 )
2014
35
Male urethral diverticulum having multiple stones. ( 25031909 )
2014
36
Management of Infected Urethral Diverticulum With Urethral Dilation. ( 25185607 )
2014
37
Urethral diverticulum misdiagnosed with cystocele. ( 24694057 )
2014
38
Congenital giant male anterior urethral diverticulum with calculi. ( 24567184 )
2014
39
Preoperative CT voiding cystourethrography using 16-multidetector CT in female urethral diverticulum. ( 25216189 )
2014
40
An unusual presentation of a urethral diverticulum as a vaginal wall mass: a case report. ( 23815779 )
2013
41
Acquired male urethral diverticulum: a complication following artificial urethral sphincter implantation. ( 24172779 )
2013
42
Primary high-grade serous carcinoma arising in the urethra or urethral diverticulum: a report of 2 cases of an extremely rare phenomenon. ( 23202781 )
2013
43
Diagnosis of female urethral diverticulum using transvaginal contrast-enhanced sonourethrography. ( 23371286 )
2013
44
Imaging of the female urethral diverticulum. ( 23561897 )
2013
45
Clear cell carcinoma of female urethral diverticulum--a case report. ( 24016613 )
2013
46
Female urethral diverticulum. ( 24054390 )
2013
47
Primary clear cell adenocarcinoma of a urethral diverticulum treated with multidisciplinary robotic anterior pelvic exenteration. ( 24454400 )
2013
48
Congenital anterior urethral diverticulum presenting with fluctuant penile mass. ( 24040607 )
2013
49
Resection of urethral diverticulum in pregnancy. ( 23884262 )
2013
50
Urethral diverticulum calculi in a male: a case report. ( 23401841 )
2013

Variations for Urethral Diverticulum

Expression for Urethral Diverticulum

Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for Urethral Diverticulum

Pathways related to Urethral Diverticulum according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.84 F3 KLK3 PVR

GO Terms for Urethral Diverticulum

Biological processes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.43 PAX8 UPK3A WT1
2 branching involved in ureteric bud morphogenesis GO:0001658 9.4 PAX8 WT1
3 metanephros development GO:0001656 9.37 NKX3-1 PAX8
4 urogenital system development GO:0001655 9.32 NKX3-1 PAX8
5 cellular response to gonadotropin stimulus GO:0071371 9.16 PAX8 WT1
6 metanephric S-shaped body morphogenesis GO:0072284 8.96 PAX8 WT1
7 metanephric epithelium development GO:0072207 8.62 PAX8 WT1

Molecular functions related to Urethral Diverticulum according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription regulatory region DNA binding GO:0044212 8.8 NKX3-1 PAX8 WT1

Sources for Urethral Diverticulum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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