MCID: URT016
MIFTS: 30

Urethral Diverticulum malady

Category: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

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Aliases & Descriptions for Urethral Diverticulum:

Name: Urethral Diverticulum 11 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:9341
ICD1029 N36.1
SNOMED-CT61 90531003
ICD9CM31 599.2
NCIt44 C39861

Summaries for Urethral Diverticulum

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Wikipedia:70 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

MalaCards based summary: Urethral Diverticulum is related to clear cell adenocarcinoma and urethritis. An important gene associated with Urethral Diverticulum is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways is FOXA1 transcription factor network. Affiliated tissues include prostate, testes and skin, and related mouse phenotype cellular.

Related Diseases for Urethral Diverticulum

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Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1clear cell adenocarcinoma30.8AMACR, PAX8
2urethritis10.9
3appendix adenocarcinoma10.5AMACR, UPK3A
4gallbladder rhabdomyosarcoma10.5KLK3, NKX3-1
5choreatic disease10.5KIDINS220, KLK3
6tenosynovitis of foot and ankle10.4AMACR, PAX8
7colon mucinous adenocarcinoma10.4AMACR, KLK3
8kidney fibrosarcoma10.4KRT7, UPK3A
9liver sarcoma10.4AMACR, WT1
10senile entropion10.4KLK3, PVR
11breast adenocarcinoma10.4KRT7, UPK3A
12guillain-barre syndrome10.4KLK3, PVR
13endometriosis of pelvic peritoneum10.4PAX8, WT1
14ovarian surface papilloma10.4AMACR, WT1
15heel spur10.4KRT7, UPK3A
16vulva squamous cell carcinoma10.4KRT7, UPK3A
17familial papillary or follicular thyroid carcinoma10.4AMACR, KRT7
18eccrine adenocarcinoma10.3KRT7, UPK3A
19pediatric ovarian dysgerminoma10.3KRT7, PAX8
20global developmental delay-lung cysts-overgrowth-wilms tumor syndrome10.3AMACR, KRT7
21biliary tract neoplasm10.3KRT7, PAX8
22adenocarcinoma10.3
23schwannoma of ureter10.3KRT7, UPK3A
24bronchus adenoma10.3AMACR, KRT7
25sphenoid sinus squamous cell carcinoma10.3KLK3, KRT7
26familial periodic paralysis10.3KLK3, KRT7
27central nervous system rhabdomyosarcoma10.3KIDINS220, WT1
28nipple neoplasm10.3KRT7, WT1
29astroblastoma10.2AMACR, KLK3, UPK3A
30sclerosing hemangioma10.2PAX8, WT1
31splenic abscess10.2AMACR, KLK3, UPK3A
32schistosomiasis10.2F3, KLK3
33large cell medulloblastoma10.2KLK3, KRT7
34vaginitis10.2
35cerebellar vermis medulloblastoma10.2AMACR, KLK3, NKX3-1
36dysostosis10.2AMACR, KLK3, NKX3-1
37adenoma10.2
38ovarian stromal hyperthecosis10.2AMACR, KLK3, PAX8
39nephrogenic adenoma10.2
40bartholin's gland small cell carcinoma10.2KLK3, KRT7
41pediatric testicular germ cell tumor10.1KRT7, WT1
42gastrointestinal system cancer10.1PAX8, WT1
43serous labyrinthitis10.1KLK3, NKX3-1
44benign neonatal seizures10.1MCU, UPK3A
45mediastinal neurilemmoma10.1KRT7, WT1
46scrotum melanoma10.0KLK3, MCU
47cervical wilms' tumor10.0AMACR, KRT7, WT1
48prostatitis10.0
49brain glioblastoma multiforme10.0KLK3, MCU, UPK3A
50bladder calculus10.0KRT7, MCU

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to urethral diverticulum

Symptoms for Urethral Diverticulum

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Drugs & Therapeutics for Urethral Diverticulum

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar UrethroplastyRecruitingNCT02634619

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

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Anatomical Context for Urethral Diverticulum

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MalaCards organs/tissues related to Urethral Diverticulum:

35
Prostate, Testes, Skin, Kidney, Colon

Animal Models for Urethral Diverticulum or affiliated genes

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MGI Mouse Phenotypes related to Urethral Diverticulum:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053846.6F3, FUT4, KIDINS220, KRT7, MCU, NKX3-1

Publications for Urethral Diverticulum

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Articles related to Urethral Diverticulum:

(show top 50)    (show all 301)
idTitleAuthorsYear
1
Female urethral diverticulum containing a urothelial carcinoma. (28057968)
2016
2
Female Urethral Diverticulum: Presentation, Diagnosis, and Predictors of Outcomes After Surgery. (27636213)
2016
3
Minimally invasive surgical approach to treat posterior urethral diverticulum. (25834967)
2015
4
Management of Infected Urethral Diverticulum With Urethral Dilation. (25185607)
2014
5
Scrotal pop off in a congenital anterior urethral diverticulum. (24928476)
2014
6
Incidence of female urethral diverticulum: a population-based analysis and literature review. (23857063)
2014
7
Congenital duplication of the urethra with urethral diverticulum: a case report. (25254101)
2014
8
Male urethral diverticulum after placement of an artificial urinary sphincter. (22438787)
2012
9
Diagnosis and management of female urethral diverticulum. (22453220)
2011
10
Laparoscopic radical cystourethrectomy in a patient with adenocarcinoma of the female urethral diverticulum. (20414429)
2010
11
Surgical reconstruction of the male urethral diverticulum. (20303576)
2010
12
Imaging of female urethral diverticulum: an update. (19001648)
2008
13
A ring-shaped stone in a female urethral diverticulum: case report and review of literature. (18317662)
2008
14
Presentation of female urethral diverticulum is usually not typical. (18204232)
2008
15
Urethral diverticulum after endoscopic urethrotomy: case report. (18068475)
2007
16
TVT can also cause urethral diverticulum. (16821000)
2007
17
Antenatal sonographic findings of congenital anterior urethral diverticulum. (15685649)
2005
18
Milk of calcium in urethral diverticulum in a male patient with paraplegia and suprapubic urinary drainage. (14713948)
2004
19
Giant urethral diverticulum in an adult male: a complication of the artificial urinary sphincter. (14501752)
2003
20
Anterior urethral diverticulum in the female: diagnosis and surgical approach. (14607049)
2003
21
Congenital anterior urethral diverticulum with stone: a unique presentation. (15061134)
2003
22
Squamous cell carcinoma in a male urethral diverticulum. (19125485)
2003
23
Double balloon positive pressure urethrography is a more sensitive test than voiding cystourethrography for diagnosing urethral diverticulum in women. (10569571)
1999
24
Female urethral diverticulum. Clinical aspects and a presentation of 15 cases. (8906011)
1996
25
Nephrogenic adenoma arising from a urethral diverticulum: magnetic resonance features. (7855983)
1995
26
Repair of urethral diverticulum by plication. (7974950)
1994
27
Carcinoma in female urethral diverticulum: case reports and review of management. (8230535)
1993
28
Sonographic demonstration of calculi within a urethral diverticulum. (8256410)
1993
29
Congenital anterior urethral diverticulum. (8220046)
1993
30
Adenocarcinoma in a female urethral diverticulum. (1750825)
1991
31
Congenital urethral diverticulum in the male: a twenty-one year old man with a congenital urethral diverticulum at the bulbous urethra. (1837946)
1991
32
Congenital anterior urethral diverticulum and recurrent urinary tract infection. (2514575)
1989
33
Sonographic appearance of urethral diverticulum in the male. (3126307)
1988
34
Urethral diverticulum in females. (3105150)
1987
35
Urethral diverticulum. (3103599)
1986
36
Urethral diverticulum prevents catheterization in male white-tailed deer (Odocoileus virginianus Zimmermann). (3951053)
1986
37
Congenital anterior urethral diverticulum. (6698087)
1984
38
The urethral diverticulum of the bull. (7182505)
1982
39
Urethral diverticulum in women. (6777021)
1980
40
Acquired male urethral diverticulum. (410952)
1977
41
Urethral diverticulum: diagnosis by ultrasound. (403810)
1977
42
Repair of urethral diverticulum or vesicovaginal fistula by vaginal flap technic. (817241)
1976
43
Letter: Urethral diverticulum presenting as a penile cyst. (804865)
1975
44
Anterior urethral diverticulum in the male: report of two cases. (804502)
1975
45
Concealed anterior urethral diverticulum causing urinary obstruction in the male child. (4628537)
1972
46
Anterior urethral diverticulum. (4973448)
1969
47
Retropublic excision of a urethral diverticulum in a female patient: a new operative procedure. (13684010)
1961
48
Urethral diverticulum in the female; a case report. (13589865)
1958
49
Stones in urethral diverticulum. (13493778)
1957
50
Urethral diverticulum in the scrotum with calculi. (18107926)
1948

Variations for Urethral Diverticulum

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Expression for genes affiliated with Urethral Diverticulum

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Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for genes affiliated with Urethral Diverticulum

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Pathways related to Urethral Diverticulum according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.8KLK3, NKX3-1

GO Terms for genes affiliated with Urethral Diverticulum

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Biological processes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1urogenital system developmentGO:000165510.3NKX3-1, PAX8
2metanephric epithelium developmentGO:007220710.1PAX8, WT1
3cellular response to gonadotropin stimulusGO:007137110.1PAX8, WT1
4metanephric S-shaped body morphogenesisGO:007228410.1PAX8, WT1
5metanephros developmentGO:000165610.0NKX3-1, PAX8
6branching involved in ureteric bud morphogenesisGO:00016589.7PAX8, WT1
7kidney developmentGO:00018229.1PAX8, UPK3A, WT1

Molecular functions related to Urethral Diverticulum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region DNA bindingGO:00442129.4NKX3-1, PAX8, WT1

Sources for Urethral Diverticulum

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet