MCID: URT016
MIFTS: 30

Urethral Diverticulum malady

Category: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

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Aliases & Descriptions for Urethral Diverticulum:

Name: Urethral Diverticulum 11 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:9341
ICD1030 N36.1
SNOMED-CT62 90531003
ICD9CM32 599.2
NCIt45 C39861

Summaries for Urethral Diverticulum

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Wikipedia:71 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

MalaCards based summary: Urethral Diverticulum is related to urethritis and adenocarcinoma. An important gene associated with Urethral Diverticulum is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways is Adhesion. Affiliated tissues include prostate, testes and skin, and related mouse phenotype cellular.

Related Diseases for Urethral Diverticulum

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Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1urethritis10.9
2adenocarcinoma10.3
3cervix endometriosis10.3AMACR, UPK3A
4ovary rhabdomyosarcoma10.3KLK3, NKX3-1
5brachyolmia10.3AMACR, PVR
6mucinous adenofibroma10.2AMACR, WT1
7alveolar echinococcosis10.2KIDINS220, UPK3A
8colon signet ring adenocarcinoma10.2AMACR, KLK3
9exotropia10.2PAX8, WT1
10progressive multifocal leukoencephalopathy10.2AMACR, WT1
11rectal disease10.2KLK3, PVR
12hypochondriasis10.2KIDINS220, KLK3
13thyroid crisis10.2KLK3, PVR
14vaginitis10.2
15adenoma10.2
16gallbladder cancer10.2AMACR, PAX8
17epithelioid cell melanoma10.2KLK3, PKDREJ
18iris spindle cell melanoma10.2AMACR, KLK3, UPK3A
19nephrogenic adenoma10.2
20ischemic fasciitis10.2KLK3, MCU
21splenic infarction10.2AMACR, KLK3, UPK3A
22adult medulloblastoma10.1AMACR, KLK3, NKX3-1
23superficial urinary bladder cancer10.1AMACR, KLK3, PAX8
24perivascular epithelioid cell tumor10.1PAX8, UPK3A, WT1
25mucinous tubular and spindle renal cell carcinoma10.1AMACR, PAX8
26bardet-biedl syndrome10.1AMACR, KLK3, NKX3-1
27rhinitis10.1AMACR, KLK3, PAX8
28clear cell adenocarcinoma10.1
29klinefelter's syndrome10.1KLK3, PAX8
30uterine corpus epithelioid leiomyoma10.1F3, KLK3
31microglandular adenosis10.1KRT7, UPK3A
32cranial nerve disease10.1KLK3, PAX8
33kimura disease10.1KRT7, PAX8
34meninges hemangiopericytoma10.1PAX8, WT1
35gastrointestinal neuroendocrine tumor10.1KRT7, PAX8
36prostate small cell carcinoma10.1KLK3, UPK3A
37brain injury10.1KLK3, MCU, UPK3A
38vulva squamous cell carcinoma10.1KRT7, UPK3A
39generalized eruptive keratoacanthoma10.1AMACR, KRT7
40klatskin's tumor10.1KRT7, UPK3A
41steroid-induced glaucoma - borderline10.1KLK3, KRT7
42angiolipomatosis, familial10.1KRT7, UPK3A
43renal pelvis carcinoma10.0AMACR, KLK3, PAX8, UPK3A
44myotonia congenita10.0KRT7, UPK3A
45thymus gland disease10.0AMACR, KLK3, PAX8, UPK3A
46prostate lymphoma10.0KLK3, KRT7
47medullomyoblastoma10.0KLK3, KRT7
48prostatitis10.0
49squamous cell carcinoma10.0
50peripheral nervous system ganglioneuroblastoma9.9AMACR, KRT7, WT1

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to urethral diverticulum

Symptoms & Phenotypes for Urethral Diverticulum

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MGI Mouse Phenotypes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053846.9F3, FUT4, KIDINS220, KRT7, MCU, NKX3-1

Drugs & Therapeutics for Urethral Diverticulum

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar UrethroplastyRecruitingNCT02634619

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

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Anatomical Context for Urethral Diverticulum

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MalaCards organs/tissues related to Urethral Diverticulum:

36
Prostate, Testes, Skin, Kidney, Colon

Publications for Urethral Diverticulum

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Articles related to Urethral Diverticulum:

(show top 50)    (show all 301)
idTitleAuthorsYear
1
Anastomotic Urethroplasty for an Obstructing Calculus Within a Bulbar Urethral Diverticulum and Urethral Stricture. (27981035)
2017
2
The Prostate in Female? Clear Cell Adenocarcinoma in a Female Urethral Diverticulum. (27789300)
2017
3
Female Urethral Diverticulum: Presentation, Diagnosis, and Predictors of Outcomes After Surgery. (27636213)
2016
4
Acute Urinary Retention in a Female Following Bladder Tumor Resection Due To a Stone in a Urethral Diverticulum. (27085569)
2016
5
Urethral Diverticulum in Women: Retrospective Case Series. (26924907)
2016
6
Long-term outcomes after the excision of horseshoe urethral diverticulum. (26670574)
2016
7
Anterior urethral diverticulum: A rare presentation. (27833294)
2016
8
Female urethral diverticulum containing a urothelial carcinoma. (28057968)
2016
9
Male urethral diverticulum uncommon entity: Our experience. (28057997)
2016
10
Preoperative 3D and 4D-CT imaging using 640-Multislice CT (640-MSCT) in diagnosis of female urethral diverticulum. (27803968)
2016
11
Congenital urethral diverticulum with infertility in an adult man and review of the literature. (27822441)
2016
12
Nephrogenic adenoma arising in a complex circumferential urethral diverticulum of a female patient with a history of childhood neuroblastoma and chemotherapy. (27324755)
2016
13
Acquired male urethral diverticulum: a rare entity treated in a one-stage procedure. (27895077)
2016
14
Surgical treatment of an acquired posterior urethral diverticulum with cystoscopy assisted robotic technique. (27440231)
2016
15
Excision of urethral diverticulum in a 24 year old woman. (25624583)
2015
16
Urethral diverticulum: a potential hazard of penile clamp application for male urinary incontinence. (25858949)
2015
17
Female Urethral Diverticulum: Current Diagnosis and Management. (26267225)
2015
18
Female urethral diverticulum containing a giant calculus: a CARE-compliant case report. (25997056)
2015
19
Congenital anterior urethral diverticulum: A case report. (26628815)
2015
20
Urethral diverticulum in the female: a meta-analysis of modern series. (26545036)
2015
21
Primary squamous cell carcinoma of the urethral diverticulum mimicking prostate cancer: Case report and review of the literature. (26029309)
2015
22
Minimally invasive surgical approach to treat posterior urethral diverticulum. (25834967)
2015
23
Congenital anterior urethral diverticulum: antenatal diagnosis with subsequent neonatal endoscopic management. (25704997)
2015
24
Urethral Diverticulum Masquerading as Anterior Vaginal Wall Cyst: A Diagnostic Dilemma. (26557574)
2015
25
Urinary retention in an infant caused by a posterior urethral diverticulum lithiasis following surgery for anorectal malformation. (24493407)
2014
26
Simple vs complex urethral diverticulum: presentation and outcomes. (25432847)
2014
27
Female urethral diverticulum: cases report and literature. (24528809)
2014
28
Urethroscopic holmium: YAG laser ablation for acquired posterior urethral diverticulum after repair of anorectal malformations. (25062769)
2014
29
Scrotal pop off in a congenital anterior urethral diverticulum. (24928476)
2014
30
Incidence of female urethral diverticulum: a population-based analysis and literature review. (23857063)
2014
31
Congenital duplication of the urethra with urethral diverticulum: a case report. (25254101)
2014
32
Urethral Diverticulum After Midurethral Sling Erosion, Excision, and Subsequent Management. (25185624)
2014
33
Nephrogenic adenoma in a urethral diverticulum. (25185615)
2014
34
Congenital anterior urethral diverticulum. (26328174)
2014
35
Male urethral diverticulum having multiple stones. (25031909)
2014
36
Management of Infected Urethral Diverticulum With Urethral Dilation. (25185607)
2014
37
Urethral diverticulum misdiagnosed with cystocele. (24694057)
2014
38
Congenital giant male anterior urethral diverticulum with calculi. (24567184)
2014
39
Preoperative CT voiding cystourethrography using 16-multidetector CT in female urethral diverticulum. (25216189)
2014
40
An unusual presentation of a urethral diverticulum as a vaginal wall mass: a case report. (23815779)
2013
41
Acquired male urethral diverticulum: a complication following artificial urethral sphincter implantation. (24172779)
2013
42
Primary high-grade serous carcinoma arising in the urethra or urethral diverticulum: a report of 2 cases of an extremely rare phenomenon. (23202781)
2013
43
Diagnosis of female urethral diverticulum using transvaginal contrast-enhanced sonourethrography. (23371286)
2013
44
Imaging of the female urethral diverticulum. (23561897)
2013
45
Clear cell carcinoma of female urethral diverticulum--a case report. (24016613)
2013
46
Female urethral diverticulum. (24054390)
2013
47
Primary clear cell adenocarcinoma of a urethral diverticulum treated with multidisciplinary robotic anterior pelvic exenteration. (24454400)
2013
48
Congenital anterior urethral diverticulum presenting with fluctuant penile mass. (24040607)
2013
49
Resection of urethral diverticulum in pregnancy. (23884262)
2013
50
Urethral diverticulum calculi in a male: a case report. (23401841)
2013

Variations for Urethral Diverticulum

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Expression for genes affiliated with Urethral Diverticulum

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Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for genes affiliated with Urethral Diverticulum

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Pathways related to Urethral Diverticulum according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3F3, KLK3, PVR

GO Terms for genes affiliated with Urethral Diverticulum

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Biological processes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1branching involved in ureteric bud morphogenesisGO:000165810.3PAX8, WT1
2cellular response to gonadotropin stimulusGO:007137110.3PAX8, WT1
3metanephric epithelium developmentGO:007220710.2PAX8, WT1
4metanephric S-shaped body morphogenesisGO:007228410.2PAX8, WT1
5metanephros developmentGO:000165610.2NKX3-1, PAX8
6kidney developmentGO:00018229.9PAX8, UPK3A, WT1
7urogenital system developmentGO:00016559.9NKX3-1, PAX8

Molecular functions related to Urethral Diverticulum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region DNA bindingGO:00442129.5NKX3-1, PAX8, WT1

Sources for Urethral Diverticulum

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet