MCID: URT016
MIFTS: 31

Urethral Diverticulum

Categories: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

MalaCards integrated aliases for Urethral Diverticulum:

Name: Urethral Diverticulum 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9341
ICD10 32 N36.1
ICD9CM 34 599.2
NCIt 46 C39861
SNOMED-CT 64 90531003
UMLS 69 C0152443

Summaries for Urethral Diverticulum

MalaCards based summary : Urethral Diverticulum is related to clear cell adenocarcinoma and nephrogenic adenoma. An important gene associated with Urethral Diverticulum is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways/superpathways is Adhesion. Affiliated tissues include prostate, testes and skin.

Wikipedia : 72 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

Related Diseases for Urethral Diverticulum

Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
# Related Disease Score Top Affiliating Genes
1 clear cell adenocarcinoma 30.4 AMACR KLK3 KRT7
2 nephrogenic adenoma 30.2 AMACR KLK3 KRT7 PAX8
3 urethritis 11.0
4 adenocarcinoma 10.4
5 prostate sarcoma 10.4 KLK3 NKX3-1
6 renal pelvis transitional cell carcinoma 10.4 KRT7 UPK3A
7 glandular cystitis 10.4 KRT7 UPK3A
8 rectal disease 10.4 KIDINS220 KLK3
9 ovarian benign neoplasm 10.4 KRT7 UPK3A
10 congenital bile acid synthesis defect 10.4 AMACR PVR
11 vulval paget's disease 10.4 KRT7 UPK3A
12 prostatic acinar adenocarcinoma 10.4 AMACR KLK3
13 nephrogenic adenoma of urinary bladder 10.3 KRT7 PAX8
14 bladder diverticulum 10.3 AMACR KRT7
15 vulva adenocarcinoma 10.3 KRT7 UPK3A
16 chronic cystitis 10.3 KRT7 UPK3A
17 bladder benign neoplasm 10.3 KRT7 PAX8
18 renal pelvis carcinoma 10.3 KRT7 UPK3A
19 clear cell papillary renal cell carcinoma 10.3 AMACR KRT7
20 lymphocele 10.3 KLK3 PKDREJ
21 radiation cystitis 10.3 KLK3 UPK3A
22 vaginitis 10.3
23 ovarian mucinous adenocarcinoma 10.3 AMACR KRT7
24 urethral syndrome 10.3 KIDINS220 KLK3
25 endocervical carcinoma 10.3 KRT7 PAX8
26 rete testis neoplasm 10.3 KLK3 PAX8
27 adenoma 10.3
28 seminal vesicle adenocarcinoma 10.3 KLK3 KRT7
29 prostate squamous cell carcinoma 10.3 KLK3 KRT7
30 endocervical adenocarcinoma 10.3 KRT7 PAX8
31 peritoneum cancer 10.3 PAX8 WT1
32 bladder adenocarcinoma 10.2 KLK3 KRT7
33 urethral benign neoplasm 10.2 AMACR KLK3 UPK3A
34 vulva cancer 10.2 KRT7 UPK3A
35 seminal vesicle tumor 10.2 KLK3 KRT7
36 suppression of tumorigenicity 12 10.2 AMACR KLK3 NKX3-1
37 adenocarcinoma in situ 10.2 KRT7 PAX8
38 male reproductive organ cancer 10.2 AMACR KLK3 NKX3-1
39 reproductive organ cancer 10.2 AMACR KLK3 NKX3-1
40 ovarian cystic teratoma 10.2 KRT7 PVR
41 female reproductive endometrioid cancer 10.2 KRT7 WT1
42 endodermal sinus tumor 10.2 KLK3 KRT7
43 nodular hidradenoma 10.2 FUT4 KRT7
44 retinal hemangioblastoma 10.2 PAX8 PKDREJ
45 kidney benign neoplasm 10.1 AMACR KRT7 PAX8
46 adenomatoid tumor 10.1 KRT7 WT1
47 collecting duct carcinoma 10.1 AMACR KRT7 PAX8
48 renal cell carcinoma, papillary, 1 10.1 AMACR KRT7 PAX8
49 prostatitis 10.1
50 infiltrative basal cell carcinoma 10.1 FUT4 KRT7

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to Urethral Diverticulum

Symptoms & Phenotypes for Urethral Diverticulum

Drugs & Therapeutics for Urethral Diverticulum

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Primary Urethral Realignment Versus Suprapubic Cystostomy After Pelvic Fracture Urethral Injury Recruiting NCT03195179

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

Anatomical Context for Urethral Diverticulum

MalaCards organs/tissues related to Urethral Diverticulum:

38
Prostate, Testes, Skin, Kidney, Colon

Publications for Urethral Diverticulum

Articles related to Urethral Diverticulum:

(show top 50) (show all 311)
# Title Authors Year
1
A rare presentation of alkaptonuria: Extensive prostatic calculi with highlight of stones found in a unique paraprostatic urethral diverticulum. ( 28779694 )
2017
2
Role of urodynamics in management of urethral diverticulum in females. ( 28807625 )
2017
3
Female Urethral Diverticulum Carcinoma: A Case Report and Literature Review. ( 28630778 )
2017
4
Urethral Diverticulum Presenting as a Large Vaginal Mass Complicating Pregnancy and Delivery. ( 29026065 )
2017
5
Diagnosis of urethral diverticulum mimicking pelvic organ prolapse with translabial ultrasonography. ( 28666694 )
2017
6
A complicated urethrovaginal fistula following an inappropriate urethral diverticulum management. ( 28805613 )
2017
7
The Prostate in Female? Clear Cell Adenocarcinoma in a Female Urethral Diverticulum. ( 27789300 )
2017
8
Anastomotic Urethroplasty for an Obstructing Calculus Within a Bulbar Urethral Diverticulum and Urethral Stricture. ( 27981035 )
2017
9
Urethral diverticulum and urolithiasis in a female guinea pig (Cavia porcellus). ( 29154708 )
2017
10
Calculus in female urethral diverticulum eroded to the vagina. ( 28283712 )
2017
11
Preliminary report on the effect of urethral diverticulum magnetic resonance imaging configuration on the incidence of new onset urodynamic stress urinary incontinence following excision. ( 29118531 )
2017
12
Anterior urethral diverticulum: A rare presentation. ( 27833294 )
2016
13
Nephrogenic adenoma arising in a complex circumferential urethral diverticulum of a female patient with a history of childhood neuroblastoma and chemotherapy. ( 27324755 )
2016
14
Long-term outcomes after the excision of horseshoe urethral diverticulum. ( 26670574 )
2016
15
Congenital anterior urethral diverticulum presenting as a scrotal mass in a two-year-old child. ( 28096926 )
2016
16
Male urethral diverticulum uncommon entity: Our experience. ( 28057997 )
2016
17
Female urethral diverticulum containing a urothelial carcinoma. ( 28057968 )
2016
18
Acquired male urethral diverticulum: a rare entity treated in a one-stage procedure. ( 27895077 )
2016
19
Surgical treatment of an acquired posterior urethral diverticulum with cystoscopy assisted robotic technique. ( 27440231 )
2016
20
Acute Urinary Retention in a Female Following Bladder Tumor Resection Due To a Stone in a Urethral Diverticulum. ( 27085569 )
2016
21
Congenital urethral diverticulum with infertility in an adult man and review of the literature. ( 27822441 )
2016
22
Female Urethral Diverticulum: Presentation, Diagnosis, and Predictors of Outcomes After Surgery. ( 27636213 )
2016
23
Preoperative 3D and 4D-CT imaging using 640-Multislice CT (640-MSCT) in diagnosis of female urethral diverticulum. ( 27803968 )
2016
24
Urethral Diverticulum in Women: Retrospective Case Series. ( 26924907 )
2016
25
Urethral diverticulum in the female: a meta-analysis of modern series. ( 26545036 )
2015
26
Urethral Diverticulum Masquerading as Anterior Vaginal Wall Cyst: A Diagnostic Dilemma. ( 26557574 )
2015
27
Primary squamous cell carcinoma of the urethral diverticulum mimicking prostate cancer: Case report and review of the literature. ( 26029309 )
2015
28
Urethral diverticulum: a potential hazard of penile clamp application for male urinary incontinence. ( 25858949 )
2015
29
Female Urethral Diverticulum: Current Diagnosis and Management. ( 26267225 )
2015
30
Female urethral diverticulum containing a giant calculus: a CARE-compliant case report. ( 25997056 )
2015
31
Minimally invasive surgical approach to treat posterior urethral diverticulum. ( 25834967 )
2015
32
Congenital anterior urethral diverticulum: A case report. ( 26628815 )
2015
33
Congenital anterior urethral diverticulum: antenatal diagnosis with subsequent neonatal endoscopic management. ( 25704997 )
2015
34
Excision of urethral diverticulum in a 24 year old woman. ( 25624583 )
2015
35
Congenital anterior urethral diverticulum. ( 26328174 )
2014
36
Urinary retention in an infant caused by a posterior urethral diverticulum lithiasis following surgery for anorectal malformation. ( 24493407 )
2014
37
Male urethral diverticulum having multiple stones. ( 25031909 )
2014
38
Urethroscopic holmium: YAG laser ablation for acquired posterior urethral diverticulum after repair of anorectal malformations. ( 25062769 )
2014
39
Scrotal pop off in a congenital anterior urethral diverticulum. ( 24928476 )
2014
40
Simple vs complex urethral diverticulum: presentation and outcomes. ( 25432847 )
2014
41
Congenital giant male anterior urethral diverticulum with calculi. ( 24567184 )
2014
42
Congenital duplication of the urethra with urethral diverticulum: a case report. ( 25254101 )
2014
43
Incidence of female urethral diverticulum: a population-based analysis and literature review. ( 23857063 )
2014
44
Urethral diverticulum misdiagnosed with cystocele. ( 24694057 )
2014
45
Female urethral diverticulum: cases report and literature. ( 24528809 )
2014
46
Nephrogenic adenoma in a urethral diverticulum. ( 25185615 )
2014
47
Urethral Diverticulum After Midurethral Sling Erosion, Excision, and Subsequent Management. ( 25185624 )
2014
48
Management of Infected Urethral Diverticulum With Urethral Dilation. ( 25185607 )
2014
49
Preoperative CT voiding cystourethrography using 16-multidetector CT in female urethral diverticulum. ( 25216189 )
2014
50
Multiple urethral anomalies: anterior urethral diverticulum, posterior urethral valves, and distal hypospadias. ( 23331841 )
2013

Variations for Urethral Diverticulum

Expression for Urethral Diverticulum

Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for Urethral Diverticulum

Pathways related to Urethral Diverticulum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.88 F3 KLK3 PVR

GO Terms for Urethral Diverticulum

Biological processes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.43 PAX8 UPK3A WT1
2 metanephros development GO:0001656 9.37 NKX3-1 PAX8
3 urogenital system development GO:0001655 9.32 NKX3-1 PAX8
4 cellular response to gonadotropin stimulus GO:0071371 9.16 PAX8 WT1
5 metanephric S-shaped body morphogenesis GO:0072284 8.96 PAX8 WT1
6 metanephric epithelium development GO:0072207 8.62 PAX8 WT1

Sources for Urethral Diverticulum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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