MCID: URT016
MIFTS: 31

Urethral Diverticulum malady

Category: Nephrological diseases

Aliases & Classifications for Urethral Diverticulum

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Aliases & Descriptions for Urethral Diverticulum:

Name: Urethral Diverticulum 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:9341
ICD1028 N36.1
SNOMED-CT60 90531003
ICD9CM30 599.2
NCIt43 C39861

Summaries for Urethral Diverticulum

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Wikipedia:69 A urethral diverticulum is a condition where the urethra or the periurethral glands push into the... more...

MalaCards based summary: Urethral Diverticulum is related to clear cell adenocarcinoma and urethritis. An important gene associated with Urethral Diverticulum is UPK3A (Uroplakin 3A). Affiliated tissues include prostate, testes and skin, and related mouse phenotypes are renal/urinary system and cellular.

Related Diseases for Urethral Diverticulum

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Diseases related to Urethral Diverticulum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1clear cell adenocarcinoma31.2AMACR, PAX8
2urethritis11.1
3appendix adenocarcinoma10.7AMACR, UPK3A
4gallbladder rhabdomyosarcoma10.7KLK3, NKX3-1
5colon mucinous adenocarcinoma10.6AMACR, KLK3
6liver sarcoma10.6AMACR, WT1
7senile entropion10.6KLK3, PVR
8tenosynovitis of foot and ankle10.6AMACR, PAX8
9endometriosis of pelvic peritoneum10.6PAX8, WT1
10organ system cancer10.6AMACR, PVR
11guillain-barre syndrome10.6KLK3, PVR
12ovarian surface papilloma10.6AMACR, WT1
13kidney fibrosarcoma10.5KRT7, UPK3A
14breast adenocarcinoma10.5KRT7, UPK3A
15heel spur10.5KRT7, UPK3A
16familial papillary or follicular thyroid carcinoma10.5AMACR, KRT7
17vulva squamous cell carcinoma10.5KRT7, UPK3A
18pediatric ovarian dysgerminoma10.5KRT7, PAX8
19schistosomiasis10.5F3, KLK3
20biliary tract neoplasm10.5KRT7, PAX8
21eccrine adenocarcinoma10.5KRT7, UPK3A
22global developmental delay-lung cysts-overgrowth-wilms tumor syndrome10.5AMACR, KRT7
23adenocarcinoma10.4
24choreatic disease10.4KIDINS220, KLK3
25astroblastoma10.4AMACR, KLK3, UPK3A
26hemangiopericytoma10.4KRT7, PAX8
27sphenoid sinus squamous cell carcinoma10.4KLK3, KRT7
28splenic abscess10.4AMACR, KLK3, UPK3A
29sclerosing hemangioma10.4PAX8, WT1
30bronchus adenoma10.4AMACR, KRT7
31nipple neoplasm10.4KRT7, WT1
32familial periodic paralysis10.4KLK3, KRT7
33schwannoma of ureter10.4KRT7, UPK3A
34cerebellar vermis medulloblastoma10.4AMACR, KLK3, NKX3-1
35dysostosis10.4AMACR, KLK3, NKX3-1
36ovarian stromal hyperthecosis10.4AMACR, KLK3, PAX8
37chromophobe adenocarcinoma10.4AMACR, KLK3, PAX8
38large cell medulloblastoma10.3KLK3, KRT7
39vaginitis10.3
40adenoma10.3
41gastrointestinal system cancer10.3PAX8, WT1
42nephrogenic adenoma10.3
43pediatric testicular germ cell tumor10.3KRT7, WT1
44bartholin's gland small cell carcinoma10.3KLK3, KRT7
45epididymal neoplasm10.3KRT7, PVR
46scrotum melanoma10.2KLK3, MCU
47benign neonatal seizures10.2MCU, UPK3A
48serous labyrinthitis10.2KLK3, NKX3-1
49central nervous system rhabdomyosarcoma10.2KIDINS220, WT1
50brain glioblastoma multiforme10.2KLK3, MCU, UPK3A

Comorbidity relations with Urethral Diverticulum via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Diverticulum:



Diseases related to urethral diverticulum

Symptoms for Urethral Diverticulum

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Drugs & Therapeutics for Urethral Diverticulum

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar UrethroplastyRecruitingNCT02634619

Search NIH Clinical Center for Urethral Diverticulum

Genetic Tests for Urethral Diverticulum

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Anatomical Context for Urethral Diverticulum

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MalaCards organs/tissues related to Urethral Diverticulum:

34
Prostate, Testes, Skin, Kidney, Colon

Animal Models for Urethral Diverticulum or affiliated genes

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MGI Mouse Phenotypes related to Urethral Diverticulum:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.1CYS1, KRT7, PAX8, UPK3A, WT1
2MP:00053846.9F3, FUT4, KIDINS220, KRT7, MCU, NKX3-1
3MP:00053766.9AMACR, CYS1, F3, KRT7, MCU, NKX3-1

Publications for Urethral Diverticulum

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Articles related to Urethral Diverticulum:

(show top 50)    (show all 293)
idTitleAuthorsYear
1
Female Urethral Diverticulum: Presentation, Diagnosis, and Predictors of Outcomes After Surgery. (27636213)
2016
2
Minimally invasive surgical approach to treat posterior urethral diverticulum. (25834967)
2015
3
Management of Infected Urethral Diverticulum With Urethral Dilation. (25185607)
2014
4
Scrotal pop off in a congenital anterior urethral diverticulum. (24928476)
2014
5
Incidence of female urethral diverticulum: a population-based analysis and literature review. (23857063)
2014
6
Congenital duplication of the urethra with urethral diverticulum: a case report. (25254101)
2014
7
Multiple urethral anomalies: anterior urethral diverticulum, posterior urethral valves, and distal hypospadias. (23331841)
2013
8
Male urethral diverticulum after placement of an artificial urinary sphincter. (22438787)
2012
9
Diagnosis and management of female urethral diverticulum. (22453220)
2011
10
Laparoscopic radical cystourethrectomy in a patient with adenocarcinoma of the female urethral diverticulum. (20414429)
2010
11
Surgical reconstruction of the male urethral diverticulum. (20303576)
2010
12
Imaging of female urethral diverticulum: an update. (19001648)
2008
13
A ring-shaped stone in a female urethral diverticulum: case report and review of literature. (18317662)
2008
14
Presentation of female urethral diverticulum is usually not typical. (18204232)
2008
15
Urethral diverticulum after endoscopic urethrotomy: case report. (18068475)
2007
16
TVT can also cause urethral diverticulum. (16821000)
2007
17
Antenatal sonographic findings of congenital anterior urethral diverticulum. (15685649)
2005
18
Milk of calcium in urethral diverticulum in a male patient with paraplegia and suprapubic urinary drainage. (14713948)
2004
19
Giant urethral diverticulum in an adult male: a complication of the artificial urinary sphincter. (14501752)
2003
20
Anterior urethral diverticulum in the female: diagnosis and surgical approach. (14607049)
2003
21
Congenital anterior urethral diverticulum with stone: a unique presentation. (15061134)
2003
22
Squamous cell carcinoma in a male urethral diverticulum. (19125485)
2003
23
Double balloon positive pressure urethrography is a more sensitive test than voiding cystourethrography for diagnosing urethral diverticulum in women. (10569571)
1999
24
Female urethral diverticulum. Clinical aspects and a presentation of 15 cases. (8906011)
1996
25
Nephrogenic adenoma arising from a urethral diverticulum: magnetic resonance features. (7855983)
1995
26
Repair of urethral diverticulum by plication. (7974950)
1994
27
Carcinoma in female urethral diverticulum: case reports and review of management. (8230535)
1993
28
Sonographic demonstration of calculi within a urethral diverticulum. (8256410)
1993
29
Congenital anterior urethral diverticulum. (8220046)
1993
30
Adenocarcinoma in a female urethral diverticulum. (1750825)
1991
31
Congenital urethral diverticulum in the male: a twenty-one year old man with a congenital urethral diverticulum at the bulbous urethra. (1837946)
1991
32
Congenital anterior urethral diverticulum and recurrent urinary tract infection. (2514575)
1989
33
Sonographic appearance of urethral diverticulum in the male. (3126307)
1988
34
Urethral diverticulum in females. (3105150)
1987
35
Urethral diverticulum. (3103599)
1986
36
Urethral diverticulum prevents catheterization in male white-tailed deer (Odocoileus virginianus Zimmermann). (3951053)
1986
37
Congenital anterior urethral diverticulum. (6698087)
1984
38
The urethral diverticulum of the bull. (7182505)
1982
39
Urethral diverticulum in women. (6777021)
1980
40
Acquired male urethral diverticulum. (410952)
1977
41
Urethral diverticulum: diagnosis by ultrasound. (403810)
1977
42
Repair of urethral diverticulum or vesicovaginal fistula by vaginal flap technic. (817241)
1976
43
Letter: Urethral diverticulum presenting as a penile cyst. (804865)
1975
44
Anterior urethral diverticulum in the male: report of two cases. (804502)
1975
45
Concealed anterior urethral diverticulum causing urinary obstruction in the male child. (4628537)
1972
46
Anterior urethral diverticulum. (4973448)
1969
47
Retropublic excision of a urethral diverticulum in a female patient: a new operative procedure. (13684010)
1961
48
Urethral diverticulum in the female; a case report. (13589865)
1958
49
Stones in urethral diverticulum. (13493778)
1957
50
Urethral diverticulum in the scrotum with calculi. (18107926)
1948

Variations for Urethral Diverticulum

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Expression for genes affiliated with Urethral Diverticulum

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Search GEO for disease gene expression data for Urethral Diverticulum.

Pathways for genes affiliated with Urethral Diverticulum

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GO Terms for genes affiliated with Urethral Diverticulum

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Biological processes related to Urethral Diverticulum according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1urogenital system developmentGO:000165510.4NKX3-1, PAX8
2metanephric epithelium developmentGO:007220710.2PAX8, WT1
3metanephric S-shaped body morphogenesisGO:007228410.2PAX8, WT1
4metanephros developmentGO:000165610.1NKX3-1, PAX8
5branching involved in ureteric bud morphogenesisGO:00016589.8PAX8, WT1
6cellular response to gonadotropin stimulusGO:00713719.7PAX8, WT1
7kidney developmentGO:00018229.2PAX8, UPK3A, WT1

Molecular functions related to Urethral Diverticulum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region DNA bindingGO:00442129.5NKX3-1, PAX8, WT1

Sources for Urethral Diverticulum

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet