MCID: URT036
MIFTS: 31

Urethral Obstruction malady

Summaries for Urethral Obstruction

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32MalaCards
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MalaCards: Urethral Obstruction, also known as obstruction of urethra, is related to prostatic hypertrophy and imperforate anus. An important gene associated with Urethral Obstruction is UBR1 (ubiquitin protein ligase E3 component n-recognin 1). Affiliated tissues include prostate, kidney and spinal cord.

Aliases & Classifications for Urethral Obstruction

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
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Aliases & Descriptions:

urethral obstruction 8 10 60
obstruction of urethra 8


External Ids:

Disease Ontology8 DOID:12577
MeSH34 D014524
SNOMED-CT56 95588004
NCIt39 C79804

Related Diseases for Urethral Obstruction

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Urethral Obstruction:



Diseases related to urethral obstruction

Clinical Features for Urethral Obstruction

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Drugs & Therapeutics for Urethral Obstruction

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Urethral Obstruction

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Anatomical Context for Urethral Obstruction

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32MalaCards
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MalaCards organs/tissues related to Urethral Obstruction:

32
Prostate, Kidney, Spinal cord, Smooth muscle, Skeletal muscle, Colon, T cells

Animal Models for Urethral Obstruction or affiliated genes

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Publications for Urethral Obstruction

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50PubMed
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Articles related to Urethral Obstruction:

(show top 50)    (show all 299)
idTitleAuthorsYear
1
Laparoscopic-assisted urinary bladder marsupialization in a goat that developed recurrent urethral obstruction following perineal urethrostomy. (22947162)
2012
2
Recurrent Johanson-Blizzard syndrome in a triplet pregnancy complicated by urethral obstruction sequence: a clinical, molecular, and immunohistochemical approach. (21711208)
2012
3
Delayed urethral obstruction after uterine torsion in a pregnant dog. (21896835)
2011
4
Chronic partial urethral obstruction in female rats: description of an experimental model and initial results. (22030825)
2011
5
Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (21168864)
2011
6
A protocol for managing urethral obstruction in male cats without urethral catheterization. (21118011)
2010
7
Foreign body urethral obstruction in a chimpanzee (Pan troglodytes). (19744169)
2009
8
Potential for recovery in bladder function after removing a urethral obstruction. (18551563)
2008
9
Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. (15913601)
2005
10
Reliability of voiding cystourethrography to detect urethral obstruction in boys. (15134990)
2004
11
Management of urinary incontinence after bulboprostatic anastomotic urethroplasty for posterior urethral obstruction secondary to pelvic fracture. (15204426)
2004
12
The use of a low-profile cystostomy tube to relieve urethral obstruction in a dog. (12873032)
2003
13
Urodynamic follow-up of experimental urethral obstruction in individual guinea pigs. (11746551)
2001
14
Transient urethral obstruction predisposes to ascending pyelonephritis and tubulo-interstitial disease: studies in rats. (11310219)
2001
15
Urethral obstruction and bilateral ureteral hydronephroses secondary to fecal impaction. (10777196)
2000
16
Predictive factors of fetal urethral obstruction: a multivariate analysis. (10782006)
2000
17
Incomplete urethral obstruction associated with dilatation of the urethra, cystitis, and pyelonephritis in a Vietnamese pot-bellied pig. (9448833)
1998
18
Prenatal diagnosis and management of urethral obstruction. (9094819)
1997
19
Urethral obstruction after anti-incontinence surgery in women: evaluation, methodology, and surgical results. (8677583)
1996
20
Medical management of feline urethral obstruction. (9157648)
1996
21
The origin of vesico-ureteric reflux in male newborns: further evidence in favour of a transient fetal urethral obstruction. (8881961)
1996
22
Obstructive anuria following fulguration of posterior urethral valves and Foley catheter drainage of the bladder. (8535698)
1995
23
Severe urethral obstruction diagnosed at 14 weeks' gestation: variability of outcome with and without drainage. (7576175)
1995
24
Stent of shape-memory alloy for urethral obstruction caused by benign prostatic hyperplasia. (7514471)
1994
25
Reversal of muscle hypertrophy in the rat urinary bladder after removal of urethral obstruction. (8082124)
1994
26
Congenital urethral obstruction: Cobb's collar or prolapsed congenital obstructive posterior urethral membrane (COPUM). (8298906)
1994
27
Urethral obstruction sequence and lower limb deficiency: evidence for the vascular disruption hypothesis. (8355115)
1993
28
Acute urethral obstruction due to condylomata acuminata. (1923242)
1991
29
Sonographic diagnosis of an obstructing urethral calculus. (3054147)
1988
30
Congenital anterior urethral diverticulum: a rare cause of lower urinary tract obstruction in childhood. (3928907)
1985
31
Localization of feline urethral obstruction. (6610978)
1984
32
Urethral obstruction and prostatitis. (6654631)
1983
33
The natural course of early intrauterine urethral obstruction. (6684886)
1983
34
Correction of congenital hydronephrosis in utero. I. The model: fetal urethral obstruction produces hydronephrosis and pulmonary hypoplasia in fetal lambs. (6875771)
1983
35
Lower limb deficiency and the urethral obstruction sequence. (6753964)
1982
36
Urethral obstruction malformation complex: a cause of abdominal muscle deficiency and the "prune belly". (156252)
1979
37
Recurrence of feline urethral obstruction. (457578)
1979
38
Feline cystitis, urethritis, urethral obstruction syndrome. Part IV: adverse drug reactions; client education. (714008)
1978
39
Cystic kidneys, renal dysplasia and microdissection data in 5 children with congenital valvular urethral obstruction. (710471)
1978
40
Obstructive posterior urethral valves: the light at the end of the tunnel. (1113426)
1975
41
Unusual urethral obstruction in a dog. (4855322)
1974
42
Approach to bladder neck and urethral obstruction in women. (4707075)
1973
43
Concealed anterior urethral diverticulum causing urinary obstruction in the male child. (4628537)
1972
44
Current concepts and feline urethral obstruction. (4949752)
1971
45
The relationship of struvite crystals to urethral obstruction in cats. (5812575)
1969
46
Urethral obstruction in male cats: transmission studies. (4238568)
1969
47
Feline urethral obstruction: mineral aspects. (5693463)
1968
48
Neo-natal ascites associated with urethral obstruction. (5626779)
1967
49
Antepubic urethrostomy for the relief of recurrent urethral obstruction in the male cat. (14353758)
1955
50
The surgery of urethral obstruction. (13132165)
1954

Genetic Variations for Urethral Obstruction

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Expression for genes affiliated with Urethral Obstruction

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Urethral Obstruction

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Pathways for genes affiliated with Urethral Obstruction

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Compounds for genes affiliated with Urethral Obstruction

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GO Terms for genes affiliated with Urethral Obstruction

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16Gene Ontology
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Cellular components related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear membraneGO:0319659.5ADRA1A, BCL2L10

Biological processes related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquitin-dependent protein catabolic processGO:0065119.6TRPC4AP, UBR1

Molecular functions related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.2BOLL, BCL2L10, VSIG4, TRPC4AP, PRUNE, CASK

Products for genes affiliated with Urethral Obstruction

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  • Antibodies
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Sources for Urethral Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet