MCID: URT036
MIFTS: 31

Urethral Obstruction malady

Summaries for Urethral Obstruction

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32MalaCards
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MalaCards: Urethral Obstruction, also known as obstruction of urethra, is related to prostatic hypertrophy and imperforate anus. An important gene associated with Urethral Obstruction is UBR1 (ubiquitin protein ligase E3 component n-recognin 1). Affiliated tissues include prostate, kidney and spinal cord.

Aliases & Classifications for Urethral Obstruction

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
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Aliases & Descriptions:

urethral obstruction 8 10 60
obstruction of urethra 8


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Disease Ontology8 DOID:12577
MeSH34 D014524
SNOMED-CT56 95588004
NCIt39 C79804

Related Diseases for Urethral Obstruction

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Urethral Obstruction:



Diseases related to urethral obstruction

Clinical Features for Urethral Obstruction

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Drugs & Therapeutics for Urethral Obstruction

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Urethral Obstruction

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Anatomical Context for Urethral Obstruction

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32MalaCards
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MalaCards organs/tissues related to Urethral Obstruction:

32
Prostate, Kidney, Spinal cord, Smooth muscle, Skeletal muscle, Colon, T cells

Animal Models for Urethral Obstruction or affiliated genes

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Publications for Urethral Obstruction

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50PubMed
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Articles related to Urethral Obstruction:

(show top 50)    (show all 299)
idTitleAuthorsYear
1
Laparoscopic-assisted urinary bladder marsupialization in a goat that developed recurrent urethral obstruction following perineal urethrostomy. (22947162)
2012
2
Re: intradetrusor botulinum neurotoxin A (BoNT-A) injections decrease bladder fibrosis secondary to partial urethral obstruction in the male rat model. Neurourol urodyn 2012;31:564-70. (22275177)
2012
3
Delayed urethral obstruction after uterine torsion in a pregnant dog. (21896835)
2011
4
Chronic partial urethral obstruction in female rats: description of an experimental model and initial results. (22030825)
2011
5
Urinary tract obstruction: New PROM questionnaire for urethral stricture surgery. (21562473)
2011
6
Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (21168864)
2011
7
Potential for recovery in bladder function after removing a urethral obstruction. (18551563)
2008
8
Catheter-induced urethral trauma in cats with urethral obstruction. (17988915)
2007
9
Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. (15913601)
2005
10
Reliability of voiding cystourethrography to detect urethral obstruction in boys. (15134990)
2004
11
Management of urinary incontinence after bulboprostatic anastomotic urethroplasty for posterior urethral obstruction secondary to pelvic fracture. (15204426)
2004
12
Diagnosis of urethral obstruction with prenatal magnetic resonance imaging. (12187261)
2002
13
Iatrogenic proximal urethral obstruction after inadvertent prostatectomy during bilateral perineal herniorrhaphy in a dog. (11963663)
2002
14
Urodynamic follow-up of experimental urethral obstruction in individual guinea pigs. (11746551)
2001
15
Variations in strategy for the treatment of urethral obstruction after a pubovaginal sling procedure. (10893603)
2000
16
Urethral obstruction and bilateral ureteral hydronephroses secondary to fecal impaction. (10777196)
2000
17
Predictive factors of fetal urethral obstruction: a multivariate analysis. (10782006)
2000
18
Surgical management of a ruptured bladder secondary to a urethral obstruction in an alpaca. (9404609)
1997
19
The effect of radiotherapy on urethral obstruction from carcinoma of the prostate. (8976773)
1996
20
Urethral obstruction after anti-incontinence surgery in women: evaluation, methodology, and surgical results. (8677583)
1996
21
Urethral obstruction after anterior colporrhaphy: correction by simple vaginoplasty. (8911534)
1996
22
Medical management of feline urethral obstruction. (9157648)
1996
23
Obstructive anuria following fulguration of posterior urethral valves and Foley catheter drainage of the bladder. (8535698)
1995
24
Severe urethral obstruction diagnosed at 14 weeks' gestation: variability of outcome with and without drainage. (7576175)
1995
25
Reversal of muscle hypertrophy in the rat urinary bladder after removal of urethral obstruction. (8082124)
1994
26
Congenital urethral obstruction: Cobb's collar or prolapsed congenital obstructive posterior urethral membrane (COPUM). (8298906)
1994
27
Developmental alterations in the fetal lamb bladder subjected to partial urethral obstruction in utero. (8345585)
1993
28
Morphological plasticity in efferent pathways to the urinary bladder of the rat following urethral obstruction. (2355259)
1990
29
Urethral obstruction in a male llama. (2599947)
1989
30
Temporary cutaneous umbilical vesicostomy in premature infants with urethral obstruction. (3950858)
1986
31
Perspectives on surgical management of feline urethral obstruction. (6377669)
1984
32
Localization of feline urethral obstruction. (6610978)
1984
33
Urethral obstruction and prostatitis. (6654631)
1983
34
The natural course of early intrauterine urethral obstruction. (6684886)
1983
35
Correction of congenital hydronephrosis in utero. I. The model: fetal urethral obstruction produces hydronephrosis and pulmonary hypoplasia in fetal lambs. (6875771)
1983
36
Posterior urethral obstruction caused by congenital posterior urethral valve; prenatal and postnatal ultrasound diagnosis. (6936625)
1981
37
Recurrence of feline urethral obstruction. (457578)
1979
38
Cystic kidneys, renal dysplasia and microdissection data in 5 children with congenital valvular urethral obstruction. (710471)
1978
39
Obstructive posterior urethral valves: the light at the end of the tunnel. (1113426)
1975
40
Unusual urethral obstruction in a dog. (4855322)
1974
41
Approach to bladder neck and urethral obstruction in women. (4707075)
1973
42
Concealed anterior urethral diverticulum causing urinary obstruction in the male child. (4628537)
1972
43
Current concepts and feline urethral obstruction. (4949752)
1971
44
Feline urethral obstruction: immunologic identification of a unique urinary protein. (4978340)
1969
45
Urethral obstruction in male cats: transmission studies. (4238568)
1969
46
Feline urethral obstruction: mineral aspects. (5693463)
1968
47
Neo-natal ascites associated with urethral obstruction. (5626779)
1967
48
URETHRAL OBSTRUCTION: CORRECTION BY SUPRAPUBIC VESICOURETHRAL SUSPENSION. (14128371)
1964
49
AN UNUSUAL BULLET WOUND PRODUCING URETHRAL OBSTRUCTION IN A DOG. (14049525)
1963
50
The surgery of urethral obstruction. (13132165)
1954

Genetic Variations for Urethral Obstruction

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Expression for genes affiliated with Urethral Obstruction

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Urethral Obstruction

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Pathways for genes affiliated with Urethral Obstruction

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Compounds for genes affiliated with Urethral Obstruction

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GO Terms for genes affiliated with Urethral Obstruction

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16Gene Ontology
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Cellular components related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear membraneGO:0319659.5ADRA1A, BCL2L10

Biological processes related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquitin-dependent protein catabolic processGO:0065119.6TRPC4AP, UBR1

Molecular functions related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.2BOLL, BCL2L10, VSIG4, TRPC4AP, PRUNE, CASK

Products for genes affiliated with Urethral Obstruction

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  • Antibodies
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  • Antibodies

Sources for Urethral Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet