MCID: URT036
MIFTS: 31

Urethral Obstruction malady

Summaries for Urethral Obstruction

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32MalaCards
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MalaCards: Urethral Obstruction, also known as obstruction of urethra, is related to prostatic hypertrophy and imperforate anus. An important gene associated with Urethral Obstruction is UBR1 (ubiquitin protein ligase E3 component n-recognin 1). Affiliated tissues include prostate, kidney and spinal cord.

Aliases & Classifications for Urethral Obstruction

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
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Aliases & Descriptions:

urethral obstruction 8 10 60
obstruction of urethra 8


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Disease Ontology8 DOID:12577
MeSH34 D014524
SNOMED-CT56 95588004
NCIt39 C79804

Related Diseases for Urethral Obstruction

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Urethral Obstruction:



Diseases related to urethral obstruction

Clinical Features for Urethral Obstruction

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Drugs & Therapeutics for Urethral Obstruction

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Urethral Obstruction

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Anatomical Context for Urethral Obstruction

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32MalaCards
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MalaCards organs/tissues related to Urethral Obstruction:

32
Prostate, Kidney, Spinal cord, Smooth muscle, Skeletal muscle, T cells, Colon

Animal Models for Urethral Obstruction or affiliated genes

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Publications for Urethral Obstruction

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50PubMed
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Articles related to Urethral Obstruction:

(show top 50)    (show all 299)
idTitleAuthorsYear
1
Prazosin in cats with urethral obstruction. (24134570)
2013
2
Large-conductance calcium-activated potassium channel activity, as determined by whole-cell patch clamp recording, is decreased in urinary bladder smooth muscle cells from male rats with partial urethral obstruction. (22520450)
2012
3
Ultra late onset group B streptococcal sepsis with acute renal failure in a child with urethral obstruction: a case report. (22348641)
2012
4
Acid-base and biochemical stabilization and quality of recovery in male cats with urethral obstruction and anesthetized with propofol or a combination of ketamine and diazepam. (23277699)
2012
5
Fluoroscopic stent placement for the relief of malignant urethral obstruction in a cat. (21091459)
2010
6
Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction. (20639056)
2010
7
Use of a balloon-expandable metallic stent to relieve malignant urethral obstruction in a cat. (19210243)
2009
8
Urethral obstruction due to the passage of a retained projectile into the genitounrinary system. (18774066)
2008
9
Corynebacterium urealyticum urinary tract infection in a cat with urethral obstruction. (18243748)
2008
10
Rare combination of unilateral renal agenesis, congenital obstructive posterior urethral membrane, and enlarged prostatic utricle, with absence of hydroureteronephrosis. (18068471)
2007
11
A novel temporary prostatic stent for the relief of prostatic urethral obstruction. (14764134)
2004
12
Effects of chronic blockade of N-methyl-D-aspartate receptors by MK-801 on neuroplasticity of the micturition reflex pathway after partial urethral obstruction in the rat. (14501783)
2003
13
Possible maternal inheritance of a common obstructive urinary tract anomaly. Report of a case of a woman with multiple urinary tract infections and two sons with posterior urethral valves. (12497693)
2002
14
Anterior urethral valves--a rare cause of urethral obstruction. (11237243)
2001
15
Urethral obstruction after primary exstrophy closure: what is the fate of the genitourinary tract? (9915471)
1999
16
Transvaginal urethrolysis for urethral obstruction after anti-incontinence surgery. (9507832)
1998
17
Congenital posterior urethral obstruction: the historical perspective. (9156879)
1997
18
Concentration of ionized calcium in plasma from cats with urethral obstruction. (9394887)
1997
19
Upregulation of nicotinamide adenine dinucleotide phosphate-diaphorase reactivity in the ventral horn motoneurons of lumbosacral spinal cord after urethral obstruction in the guinea pig. (9100259)
1997
20
Increased NADPH-diaphorase reactivity in bladder afferent pathways following urethral obstruction in guinea pigs. (10975742)
1997
21
Prepubic urethrostomy for relief of urethral obstruction in a sheep and a goat. (9096724)
1997
22
Pathophysiology of urethral obstruction. (8711861)
1996
23
Evaluation of cervico-urethral obstruction with ambulatory pressure/flow studies: an alternative to conventional pressure/flow studies? (7540477)
1995
24
Effect of naftopidil on urethral obstruction in benign prostatic hyperplasia: assessment by urodynamic studies. (7517541)
1994
25
Evaluation of cervico-urethral obstruction with ambulatory pressure/flow studies: an alternative to conventional pressure/flow studies? (7530940)
1994
26
Transurethral radiotherapy for benign prostatic hypertrophy-related urethral obstruction. Dosimetry, ethics, and preliminary results. (7522461)
1994
27
Urethral obstruction of 6 hours or less causes bacteriuria, bacteremia, and pyelonephritis in mice challenged with "nonuropathogenic" Escherichia coli. (8335372)
1993
28
Familial segregation of cervical ribs, Sprengel anomaly, preaxial polydactyly, anal atresia, and urethral obstruction: a new syndrome? (8456850)
1993
29
Investigations on dietary treatment of struvite urolithiasis: 3. Effect of an acidifying diet on acid-base- and mineral-balance of cats after acute urethral obstruction. (8306863)
1993
30
Giant bladder diverticulum causing urethral obstruction in an infant. (1623392)
1992
31
The guinea pig as a model of gradual urethral obstruction. (2005718)
1991
32
Urethral obstruction owing to retroperitoneal cystic lymphangioma. (3298695)
1987
33
Fetal urethral obstruction: US evaluation. (3898218)
1985
34
Adverse drug reactions in cats with feline urethral obstruction. (6377671)
1984
35
Pathogenesis of the prune-belly syndrome: a functional urethral obstruction caused by prostatic hypoplasia. (6231520)
1984
36
Immediate relief of feline urethral obstruction. (6610981)
1984
37
Therapy of feline urethral obstruction. (17422484)
1984
38
Prune belly syndrome and urethral obstruction. (6444668)
1980
39
Bladder diverticula causing posterior urethral obstruction in children. (112263)
1979
40
Alpha-adrenergic agents in urinary disorders of the proximal urethra. Part II. Urethral obstruction due to "sympathetic dyssynergia". (37973)
1978
41
Characterization and treatment of acid-base and renal defects due to urethral obstruction in cats. (640942)
1978
42
Posterior urethral obstruction: valvular or diaphragmatic? Endoscopic diagnosis and treatment. (588720)
1977
43
Hyperkalemia in cats with urethral obstruction. Electrocardiographic abnormalities and treatment. (867738)
1977
44
Characterization and treatment of water, electrolyte, and acid-base imbalances of induced urethral obstruction in the cat. (879580)
1977
45
Surgical relief for urethral obstruction due to sabulous calculi in the male cat. (1039206)
1975
46
Seondary bladder neck obstruction in patients with urethral valves: treatment with phenoxybenzamine. (1136085)
1975
47
An unusual cause of urethral obstruction in the dog. (5077658)
1972
48
ENDOSCOPIC INVESTIGATION AND DIAGNOSIS OF URETHRAL OBSTRUCTION IN CHILDREN. (14195873)
1964
49
Perineal urethrostomy to relieve urethral obstruction in the male cat. (14018555)
1963
50
Posterior Urethral Obstruction in Childhood: (Section of Urology). (19991686)
1938

Genetic Variations for Urethral Obstruction

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Expression for genes affiliated with Urethral Obstruction

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Urethral Obstruction

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Pathways for genes affiliated with Urethral Obstruction

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Compounds for genes affiliated with Urethral Obstruction

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GO Terms for genes affiliated with Urethral Obstruction

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16Gene Ontology
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Cellular components related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear membraneGO:0319659.5ADRA1A, BCL2L10

Biological processes related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquitin-dependent protein catabolic processGO:0065119.6TRPC4AP, UBR1

Molecular functions related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.2BOLL, BCL2L10, VSIG4, TRPC4AP, PRUNE, CASK

Products for genes affiliated with Urethral Obstruction

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  • Antibodies
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Sources for Urethral Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet