MCID: URT036
MIFTS: 31

Urethral Obstruction malady

Summaries for Urethral Obstruction

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33MalaCards
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MalaCards: Urethral Obstruction, also known as obstruction of urethra, is related to imperforate anus and urethral obstruction sequence. An important gene associated with Urethral Obstruction is UBR1 (ubiquitin protein ligase E3 component n-recognin 1). Affiliated tissues include spinal cord, kidney and smooth muscle.

Aliases & Classifications for Urethral Obstruction

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
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Aliases & Descriptions:

urethral obstruction 8 10 61
obstruction of urethra 8


External Ids:

Disease Ontology8 DOID:12577
MeSH35 D014524
SNOMED-CT57 95588004
NCIt40 C79804

Related Diseases for Urethral Obstruction

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Urethral Obstruction:



Diseases related to urethral obstruction

Clinical Features for Urethral Obstruction

Drugs & Therapeutics for Urethral Obstruction

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Urethral Obstruction

Drug clinical trials:

Search ClinicalTrials for Urethral Obstruction

Search NIH Clinical Center for Urethral Obstruction

Search CenterWatch for Urethral Obstruction

Genetic Tests for Urethral Obstruction

Anatomical Context for Urethral Obstruction

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33MalaCards
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MalaCards organs/tissues related to Urethral Obstruction:

33
Spinal cord, Kidney, Smooth muscle, Skeletal muscle, Colon, Prostate, T cells, B cells

Animal Models for Urethral Obstruction or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Urethral Obstruction

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51PubMed
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Articles related to Urethral Obstruction:

(show top 50)    (show all 286)
idTitleAuthorsYear
1
Robotic-Assisted Urethrolysis for Urethral Obstruction After Retropubic Bladder Neck Suspension-A Case Series Report. (24074259)
2013
2
Preliminary Experience With Stenting for Management of Non-Urolith Urethral Obstruction in Eight Cats. (24350569)
2013
3
Evaluation of risk factors associated with recurrent obstruction in cats treated medically for urethral obstruction. (24094261)
2013
4
Urethral obstruction with a copulatory plug following natural breeding in a ruffed lemur, Varecia rubra. (24372394)
2013
5
Changes of neuregulin-1(NRG-1) expression in a rat model of overactive bladder induced by partial urethral obstruction: is NRG-1 a new biomarker of overactive bladder? (24152577)
2013
6
Large-conductance calcium-activated potassium channel activity, as determined by whole-cell patch clamp recording, is decreased in urinary bladder smooth muscle cells from male rats with partial urethral obstruction. (22520450)
2012
7
Ultra late onset group B streptococcal sepsis with acute renal failure in a child with urethral obstruction: a case report. (22348641)
2012
8
Acid-base and biochemical stabilization and quality of recovery in male cats with urethral obstruction and anesthetized with propofol or a combination of ketamine and diazepam. (23277699)
2012
9
Impact of partial urethral obstruction on bladder function: time-dependent changes and functional correlates of altered expression of CaA^a8_ signaling regulators. (22442207)
2012
10
Coccygeal epidural with local anesthetic for catheterization and pain management in the treatment of feline urethral obstruction. (21288294)
2011
11
Urinary tract obstruction: New PROM questionnaire for urethral stricture surgery. (21562473)
2011
12
Retrospective study to characterize post-obstructive diuresis in cats with urethral obstruction. (20655493)
2010
13
Urethral obstruction by seminal coagulum is associated with medetomidine-ketamine anesthesia in male mice on C57BL/6J and mixed genetic backgrounds. (19476720)
2009
14
Corynebacterium urealyticum urinary tract infection in a cat with urethral obstruction. (18243748)
2008
15
Two- and 3-dimensional ultrasonography in acute urinary retention due to distal urethral obstruction by infiltrating metastatic colon cancer. (17255191)
2007
16
Two- and three-dimensional sonographic findings in a case of distal urethral obstruction due to a paraurethral tumor. (15846764)
2005
17
Lateral excision of tension-free vaginal tape for the treatment of iatrogenic urethral obstruction. (15932860)
2005
18
A novel temporary prostatic stent for the relief of prostatic urethral obstruction. (14764134)
2004
19
Penile urethral obstruction in a subject with spinal cord injury. (12746745)
2003
20
Congenital urethral obstruction, bilateral hydronephrosis and uroperitoneum in a lamb. (12739604)
2003
21
Diagnosis of urethral obstruction with prenatal magnetic resonance imaging. (12187261)
2002
22
Functional urethral obstruction in 3 dogs: clinical and urethral pressure profile findings. (10668816)
2000
23
Congenital posterior urethral obstruction: the historical perspective (9069204)
1997
24
Urethral obstruction after anterior colporrhaphy: correction by simple vaginoplasty. (8911534)
1996
25
Medical management of feline urethral obstruction. (9157648)
1996
26
Familial segregation of cervical ribs, Sprengel anomaly, preaxial polydactyly, anal atresia, and urethral obstruction: a new syndrome? (8456850)
1993
27
Anesthesia for feline urethral obstruction. (1585609)
1992
28
The guinea pig as a model of gradual urethral obstruction. (2005718)
1991
29
Prostate development in prune belly syndrome (PBS) and posterior urethral valves (PUV): etiology of PBS--lower urinary tract obstruction or primary mesenchymal defect? (2014185)
1991
30
Rupture of ileal neobladder due to urethral obstruction by mucous plug. (2388342)
1990
31
Morphological plasticity in efferent pathways to the urinary bladder of the rat following urethral obstruction. (2355259)
1990
32
Congenital urethral obstruction, uroperitoneum, and omphalitis in a calf. (3558083)
1987
33
Adverse drug reactions in cats with feline urethral obstruction. (6377671)
1984
34
Pathogenesis of the prune-belly syndrome: a functional urethral obstruction caused by prostatic hypoplasia. (6231520)
1984
35
Diet-induced feline urethral obstruction. (6610977)
1984
36
Posterior urethral obstruction caused by congenital posterior urethral valve; prenatal and postnatal ultrasound diagnosis. (6936625)
1981
37
Antenatal ultrasonic diagnosis of complete urethral obstruction in the fetus. (7446014)
1980
38
Prune belly syndrome and urethral obstruction. (6444668)
1980
39
Feline cystitis, urethritis, urethral obstruction syndrome. Part III. Prophylaxis. (27715)
1978
40
Use of a silicone shunt for the surgical relief of feline urethral obstruction. (636253)
1978
41
The radiologic and pathologic spectrum of the prune belly syndrome. The importance of urethral obstruction in prognosis. (139635)
1977
42
Chronic urethral obstruction in a cat. (1051765)
1976
43
The diagnosis of fetal hydronephrosis, megaureter and urethral obstruction by ultrasonic echography. (1168479)
1975
44
Preputial urethroplasty for relief of urethral obstruction in the male cat. (1089621)
1975
45
Congenital urethral membranes causing urethral obstruction. (4810775)
1974
46
A critical evaluation of urethral obstruction in female children. (4572069)
1973
47
Surgically induced partial urinary obstruction in the fetal lamb. II. Urethral obstruction. (5037967)
1972
48
An unusual case of feline urethral obstruction. (5533237)
1970
49
Feline urethral obstruction: immunologic identification of a unique urinary protein. (4978340)
1969
50
Urethral obstruction in the female child. (13583054)
1958

Genetic Variations for Urethral Obstruction

Expression for genes affiliated with Urethral Obstruction

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Urethral Obstruction

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Pathways for genes affiliated with Urethral Obstruction

Compounds for genes affiliated with Urethral Obstruction

GO Terms for genes affiliated with Urethral Obstruction

Sources:
16Gene Ontology
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Cellular components related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear membraneGO:0319659.5ADRA1A, BCL2L10

Biological processes related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquitin-dependent protein catabolic processGO:0065119.6TRPC4AP, UBR1

Molecular functions related to Urethral Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.2BOLL, BCL2L10, VSIG4, TRPC4AP, PRUNE, CASK

Products for genes affiliated with Urethral Obstruction

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Sources for Urethral Obstruction

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet