Aliases & Classifications for Urethral Syndrome

Summaries for Urethral Syndrome

MedlinePlus : 40 The urethra is the tube that allows urine to pass out of the body. In men, it's a long tube that runs through the penis. It also carries semen in men. In women, it's short and is just above the vagina. Urethral problems may happen due to aging, illness, or injury. They include Urethral cancer - a rare cancer that happens more often in men Urethral stricture - a narrowing of the opening of the urethra Urethritis - inflammation of the urethra, sometimes caused by infection Urethral problems may cause pain or difficulty passing urine. You may also have bleeding or discharge from the urethra. Doctors diagnose urethral problems using different tests. These include urine tests, x-rays and an examination of the urethra with a scope called a cystoscope. Treatment depends on the cause of the problem. It may include medicines and, in severe cases, surgery.

MalaCards based summary : Urethral Syndrome, also known as urethral diseases, is related to urethritis and bacteriuria, and has symptoms including pain in urethra An important gene associated with Urethral Syndrome is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways is Primary immunodeficiency. The drugs Cholinergic Agents and Cholinergic Antagonists have been mentioned in the context of this disorder. Affiliated tissues include the urethra, testes and prostate.

Disease Ontology : 12 A urinary system disease that is located in the urethra.

Wikipedia : 72 Urethral syndrome is characterised by a set of symptoms typically associated with lower urinary tract... more...

Related Diseases for Urethral Syndrome

Diseases related to Urethral Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 urethritis 30.5 CD40LG CD79A MRAP MT-TG PHB2
2 bacteriuria 29.3 CD40LG CD79A
3 pyuria 10.5 BCKDHA MRAP
4 ochronosis 10.5 HPD MRAP
5 balanitis 10.5 MRAP PHB2
6 enthesopathy 10.5 MRAP PHB2
7 penile disease 10.5 MRAP PHB2
8 bursitis 10.5 MRAP PHB2
9 tendinitis 10.5 MRAP PHB2
10 bladder neck obstruction 10.4 KLK3 SAMHD1
11 prostatic cyst 10.4 BCL2L10 KLK3
12 acute cystitis 10.4 BCKDHA KLK3
13 purulent endophthalmitis 10.4 MRAP SAMHD1
14 urethral stricture 10.4 BCL2L10 KLK3
15 anterior scleritis 10.3 CD79A MRAP
16 chronic orbital inflammation 10.3 CD79A MRAP
17 rectal disease 10.3 KIDINS220 KLK3
18 urethral diverticulum 10.2 KIDINS220 KLK3
19 optic papillitis 10.2 CD40LG MRAP
20 acute retinal necrosis syndrome 10.2 CD40LG MRAP
21 cervicitis 10.2 CD79A MRAP MT-TG
22 iridocyclitis 10.1 CD40LG MRAP
23 dysentery 10.1 CD79A PHB2
24 plasmodium malariae malaria 10.1 CD40LG SAMHD1
25 myasthenic syndrome, congenital, 10 10.1 CD40LG MT-TG
26 urethral gland abscess 10.0
27 panuveitis 10.0 CD40LG MRAP
28 cystitis 10.0
29 selective igg deficiency disease 10.0 CD40LG CD79A
30 c1q nephropathy 10.0 CD40LG CD79A
31 meningovascular neurosyphilis 10.0 CD40LG CD79A
32 alpha chain disease 10.0 CD40LG CD79A
33 brill-zinsser disease 10.0 CD40LG CD79A
34 exudative glomerulonephritis 10.0 CD40LG CD79A
35 cork-handlers' disease 10.0 CD40LG CD79A
36 salpingo-oophoritis 10.0 CD40LG CD79A
37 chorioretinal scar 10.0 CD40LG SAMHD1
38 early yaws 10.0 CD40LG CD79A
39 ventilation pneumonitis 10.0 CD40LG CD79A
40 chronic interstitial cystitis 10.0 CD40LG CD79A
41 axillary adenitis 10.0 CD40LG CD79A
42 cryofibrinogenemia 10.0 CD40LG CD79A
43 trichostrongyloidiasis 10.0 CD40LG CD79A
44 subacute bacterial endocarditis 10.0 CD40LG CD79A
45 heterophyiasis 10.0 CD40LG CD79A
46 immunoglobulin g deficiency 10.0 CD40LG CD79A
47 orbital granuloma 10.0 CD40LG CD79A
48 transient hypogammaglobulinemia of infancy 10.0 CD40LG CD79A
49 hyperglobulinemic purpura 10.0 CD40LG CD79A
50 gastroduodenitis 10.0 CD40LG CD79A

Comorbidity relations with Urethral Syndrome via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Urethral Syndrome:



Diseases related to Urethral Syndrome

Symptoms & Phenotypes for Urethral Syndrome

UMLS symptoms related to Urethral Syndrome:


pain in urethra

Drugs & Therapeutics for Urethral Syndrome

Drugs for Urethral Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cholinergic Agents Phase 2
2 Cholinergic Antagonists Phase 2
3 Muscarinic Antagonists Phase 2
4 Neurotransmitter Agents Phase 2
5 Solifenacin succinate Phase 2 242478-38-2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety And Efficacy Of Solifenacin In Men With Overactive Bladder (OAB) And Detrusor Underactivity Completed NCT00441428 Phase 2 solifenacin

Search NIH Clinical Center for Urethral Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: urethral diseases

Genetic Tests for Urethral Syndrome

Genetic tests related to Urethral Syndrome:

# Genetic test Affiliating Genes
1 Abnormality of the Urethra 28

Anatomical Context for Urethral Syndrome

The Foundational Model of Anatomy Ontology organs/tissues related to Urethral Syndrome:

18
The Urethra

MalaCards organs/tissues related to Urethral Syndrome:

38
Testes, Prostate, Cervix

Publications for Urethral Syndrome

Articles related to Urethral Syndrome:

(show top 50) (show all 131)
# Title Authors Year
1
Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. ( 26760182 )
2016
2
Epidemiology and laboratory characteristics of Trichomonas vaginalis infection in Croatian men with and without urethritis syndrome: a case-control study. ( 25568091 )
2015
3
A prospective study to evaluate the efficacy of cistiquer in improving lower urinary tract symptoms in females with urethral syndrome. ( 25034330 )
2014
4
The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. ( 21176078 )
2011
5
The detection of urethritis pathogens among patients with the male urethritis syndrome, genital ulcer syndrome and HIV voluntary counselling and testing clients: should South Africa's syndromic management approach be revised? ( 18192290 )
2008
6
Treatment of urethral syndrome: a prospective randomized study with Nd:YAG laser. ( 16493214 )
2006
7
Urethral syndrome: response to alpha-adrenergic blocking agents. ( 16261427 )
2006
8
Treatment of post-menopausal urethral syndrome with the formula niao chang shu--a report of 40 cases. ( 15119161 )
2004
9
Dr. Li Yueqing's experience in treating female urethral syndrome. ( 15270256 )
2004
10
Electric acupuncture in the treatment of 36 cases of female urethral syndrome. ( 14719301 )
2003
11
Prostatitis, interstitial cystitis, chronic pelvic pain, and urethral syndrome share a common pathophysiology: lower urinary dysfunctional epithelium and potassium recycling. ( 14665339 )
2003
12
Transabdominal vesical sonography of urethral syndrome and stress incontinence. ( 12534925 )
2003
13
Treatment of female urethral syndrome refractory to antibiotics. ( 12402379 )
2002
14
Intravesical potassium sensitivity in patients with interstitial cystitis and urethral syndrome. ( 11248610 )
2001
15
Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. ( 11822223 )
2001
16
The incidence of Chlamydia trachomatis in women with urethral syndrome. ( 11695072 )
2001
17
Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline. ( 11330365 )
2001
18
Duration of clinical symptoms in female patients with acute urethral syndrome caused by Ureaplasma urealyticum treated with azithromycin or doxycycline. ( 11154040 )
2000
19
Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. ( 10789560 )
2000
20
Equal symptomatic outcome after antibacterial treatment of acute lower urinary tract infection and the acute urethral syndrome in adult women. ( 10555247 )
1999
21
Urethral syndrome and associated risk factors related to obstetrics and gynecology. ( 10221602 )
1999
22
Urinary bacterial flora of women with urethral syndrome and interstitial cystitis. ( 9852391 )
1999
23
Study on acupuncture and moxibustion therapy for female urethral syndrome. ( 10437230 )
1998
24
1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. ( 8912627 )
1996
25
Female urethral syndrome. A female prostatitis? ( 8686301 )
1996
26
Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. ( 7629982 )
1995
27
Evolving strategies for management of the nongonococcal urethritis syndrome. ( 7629989 )
1995
28
The urethral syndrome: a controlled evaluation. J Psychosom Res 1993; 37: 737-743. ( 8027965 )
1994
29
Urethral syndrome: clinical results with antibiotics alone or combined with estrogen. ( 7957464 )
1994
30
Fibromyalgia associated with female urethral syndrome. ( 8187451 )
1994
31
The urethral syndrome and its management. ( 7928838 )
1994
32
The urethral syndrome: a controlled evaluation. ( 8229904 )
1993
33
The urethral syndrome--why what we do works, or doesn't. ( 1479977 )
1992
34
Surgical repair of hypospadias in women with symptoms of urethral syndrome. ( 1569664 )
1992
35
A psychophysiological evaluation of female urethral syndrome: evidence for a muscular abnormality. ( 1625341 )
1992
36
The urethral syndrome: myth or reality? A commentary. ( 2233643 )
1990
37
The painful bladder: urethral syndrome and interstitial cystitis. ( 2130959 )
1990
38
Genitourinary manifestations of fibrositis: an increased association with the female urethral syndrome. ( 2319522 )
1990
39
Prostatodynia or painful male urethral syndrome? ( 2385883 )
1990
40
Cryosurgery versus dilation and massage for the treatment of recurrent urethral syndrome. ( 2810238 )
1989
41
Pharmacokinetic data and therapeutic efficacy of miocamycin: serum, urinary and prostatic levels. Therapeutic aspects in acute urethral syndrome and non-gonococcal urethritis. ( 16312542 )
1989
42
Urethral syndrome: a study in psychosomatic urology. ( 2486388 )
1989
43
Urethral syndrome. A comparison of different treatment modalities. ( 2926732 )
1989
44
Interstitial cystitis and the urethral syndrome: a possible answer. ( 2670041 )
1989
45
The urethral syndrome. ( 3170107 )
1988
46
The urethral syndrome. ( 3055620 )
1988
47
Sexually transmitted diseases in women with urethral syndrome. ( 2903082 )
1988
48
Urethral syndrome: patient suggestions. ( 3420419 )
1988
49
Efficacy of miocamycin in the therapy of non-specific genital infections (NSGI): non-gonococcal urethritis (NGU) and acute urethral syndrome (AUS). ( 3259948 )
1988
50
The acute urethral syndrome in routine practice. ( 3494789 )
1987

Variations for Urethral Syndrome

Expression for Urethral Syndrome

Search GEO for disease gene expression data for Urethral Syndrome.

Pathways for Urethral Syndrome

Pathways related to Urethral Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.19 CD40LG CD79A

GO Terms for Urethral Syndrome

Biological processes related to Urethral Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Urethral Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....