MCID: URT001
MIFTS: 55

Urethritis malady

Nephrological diseases category
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Summaries for Urethritis

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Wikipedia:65 Urethritis is inflammation of the urethra. The most common symptom is painful or difficult urination. more...

MalaCards based summary: Urethritis, also known as non-gonococcal urethritis, is related to prostatitis and trachoma. An important gene associated with Urethritis is HSPD1 (heat shock 60kDa protein 1 (chaperonin)), and among its related pathways are Selected targets of GCR alpha and Legionellosis. The compounds bifidobacterium and tuberculin have been mentioned in the context of this disorder. Affiliated tissues include prostate, testes and kidney.

Aliases & Classifications for Urethritis

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 44Novoseek, 39NCIt, 57SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
See all sources

Urethritis, Aliases & Descriptions:

Name: Urethritis 8 10
Non-Gonococcal Urethritis 8 62
Nongonococcal Urethritis 8 44
 
Nonspecific Urethritis 8 62
Urethritis, Unspecified 8
Urethritis Unspecified 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology8 DOID:1343
NCIt39 C26904
ICD9CM27 597.80
MeSH34 D014526
ICD1025 N34.1, N37.0

Related Diseases for Urethritis

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Graphical network of the top 20 diseases related to Urethritis:



Diseases related to urethritis

Symptoms for Urethritis

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Drugs & Therapeutics for Urethritis

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Drug clinical trials:

Search ClinicalTrials for Urethritis

Search NIH Clinical Center for Urethritis

Genetic Tests for Urethritis

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Anatomical Context for Urethritis

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MalaCards organs/tissues related to Urethritis:

32
Prostate, Testes, Kidney, Skin, Spinal cord, Colon, Bone, Small intestine, Pancreas, Heart, Smooth muscle, T cells, Neutrophil, Brain, Skeletal muscle, Lung, Ovary, Cervix, Endothelial

Animal Models for Urethritis or affiliated genes

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Publications for Urethritis

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Articles related to Urethritis:

(show top 50)    (show all 2579)
idTitleAuthorsYear
1
Re: Complete urethral duplication: description of surgical approach mimicking distal epispadias repair. (24703151)
2014
2
Management of Infected Urethral Diverticulum With Urethral Dilation. (25185607)
2014
3
Neonatal presentation of posterior urethral valves and tethered spinal cord. (25073498)
2014
4
Renal Parenchymal Area and Risk of ESRD in Boys with Posterior Urethral Valves. (24311709)
2013
5
First experiences with the Spannera8c temporary prostatic stent for prostatic urethral obstruction. (23886821)
2013
6
Posterior urethral valves: determinants of outcome in a developing country. (23331631)
2013
7
Robotic-Assisted Urethrolysis for Urethral Obstruction After Retropubic Bladder Neck Suspension-A Case Series Report. (24074259)
2013
8
Urethral strictures following urethral plate and proximal urethral elevation during proximal TIP hypospadias repair. (23707201)
2013
9
Commentary to 'Role of urethral bulking agents in epispadias/exstrophy complex patients' (24183655)
2013
10
Urethral diverticulum calculi in a male: a case report. (23401841)
2013
11
Re: Preputial/penile skin flap, as a dorsal onlay or tubularized flap: a versatile substitute for complex anterior urethral stricture. (23931204)
2013
12
Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia. (24073977)
2013
13
PCR for diagnosis of male Trichomonas vaginalis infection with chronic prostatitis and urethritis. (22711929)
2012
14
Development of a porcine animal model for urethral stricture repair using autologous urothelial cells. (21398188)
2012
15
The clinical spectrum of the presenting signs and symptoms of anterior urethral stricture: detailed analysis of a single institutional cohort. (22446349)
2012
16
Risk factors associated with chronic kidney disease in patients with posterior urethral valves without prenatal hydronephrosis. (21527193)
2011
17
Coccygeal epidural with local anesthetic for catheterization and pain management in the treatment of feline urethral obstruction. (21288294)
2011
18
In vitro activity of azithromycin against Mycoplasma genitalium and its efficacy in the treatment of male Mycoplasma genitalium-positive nongonococcal urethritis. (21710162)
2011
19
Management of anterior urethral stricture: an evidence-based approach. (20827208)
2010
20
Fluoroscopic stent placement for the relief of malignant urethral obstruction in a cat. (21091459)
2010
21
A rare cause of ascites in a newborn: posterior urethral valve. (20158664)
2010
22
The new pattern of urethral stricture disease in Lagos, Nigeria. (19606199)
2009
23
Posterior urethral valves are often associated with cryptorchidism and inguinal hernias. (18554641)
2008
24
Staged pendulous-prostatic anastomotic urethroplasty followed by reconstruction of the anterior urethra: an effective treatment for long-segment bulbar and membranous urethral stricture. (16904816)
2007
25
A comparison of clinical features between chlamydial and non-chlamydial urethritis in men negative for gonococcal infection who attended a urological outpatient clinic in Japan. (17211572)
2007
26
Management of urethral hemangiomas associated with Klippel-Trenaunay-Weber syndrome by endoscopic sclerotherapy. (17645615)
2007
27
Renal transplantation in children with posterior urethral valves. (16491414)
2006
28
Urethral obstruction due to lobular mesonephric hyperplasia of the vagina--a case report. (16758778)
2005
29
Suprapubic electroresection of prostate in three patients with benign prostatic hyperplasia and previous surgery for long urethral stricture. (15833539)
2005
30
Asymptomatic Chlamydia trachomatis-negative non-gonococcal urethritis. (15899091)
2005
31
Long-term followup of bilateral high (sober) urinary diversion in patients with posterior urethral valves and its effect on bladder function. (15821568)
2005
32
Meningococcal urethritis in a heterosexual man. (15278728)
2004
33
Transvaginal sonographic findings in diagnosis and treatment of urethral stricture. (14682433)
2003
34
Prevalence of asymptomatic chlamydial urethritis in military recruits in the Celje region, Slovenia. (14624741)
2003
35
Posterior urethral valves: prognostic factors. (12699486)
2003
36
Risk behaviours associated with urethritis and genital ulcer disease in prison inmates, Sindh, Pakistan. (15568455)
2002
37
Posterior urethral valves. (11294257)
2001
38
Increased urinary transforming growth factor-beta(1) excretion in children with posterior urethral valves. (10925100)
2000
39
Equal symptomatic outcome after antibacterial treatment of acute lower urinary tract infection and the acute urethral syndrome in adult women. (10555247)
1999
40
Urethritis and cervicitis. (10330757)
1999
41
Urethral diverticulum and urethrocutaneous fistula presenting as a mass over the medical thigh. (9722775)
1998
42
Congenital posterior urethral obstruction: the historical perspective. (9156879)
1997
43
Prevention of urethral stricture recurrence using clean intermittent self-catheterization. (8032838)
1994
44
Mercapto-acetyltriglycine (MAG 3) renography and indirect radionuclide cystography in posterior urethral valves. (7827852)
1994
45
Urinary tract infections and the urethral syndrome in adult women: pathogenesis, diagnosis, and therapy. (3902456)
1985
46
The ultrastructure of human male urethral stricture. (1222353)
1975
47
Carcinoma of Skene's gland associated with urethral diverticulum: a case report. (4369830)
1974
48
Congenital urethral membranes causing urethral obstruction. (4810775)
1974
49
Urethral stricture. (4691433)
1973
50
Case of Vesico-urethral Calculus. (19983442)
1923

Variations for Urethritis

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Expression for genes affiliated with Urethritis

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Expression patterns in normal tissues for genes affiliated with Urethritis

Search GEO for disease gene expression data for Urethritis.

Pathways for genes affiliated with Urethritis

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Pathways related to Urethritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5IL8, HSPD1
29.5IL8, HSPD1
3
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.4IL8, DEFB4A
4
Show member pathways
9.2DEFA5, DEFB4A

Compounds for genes affiliated with Urethritis

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Compounds related to Urethritis according to GeneCards/GeneDecks:

(show top 50)    (show all 61)
idCompoundScoreTop Affiliating Genes
1bifidobacterium4410.0HSPD1, LTF
2tuberculin449.9CD79A, HSPD1
3hypothiocyanite44 2410.9CD79A, LTF
4lactulose449.9LTF, CD79A
5pneumococcal449.9LTF, CD79A
6thiocyanate44 2410.9LTF, CD79A
7toxin-1449.8IL8, HSPD1
8pmma449.8LTF, CD79A
9fluconazole44 1110.8LTF, CD79A
10hcec449.8DEFB4A, IL8
11citric acid44 28 24 1112.7HSPD1, LTF
12azithromycin44 1110.7CD79A, IL8
13lipoteichoic acid449.6IL8, DEFB4A
14budesonide44 50 1111.6IL8, LTF
15sulfasalazine28 44 50 1112.6IL8, CD79A
16protamine449.5LTF, IL8
17doxycycline44 1110.5HSPD1, CD79A, LTF
18anti-fungal449.5CD79A, DEFB4A, LTF
19flagellin44 2810.5DEFB4A, HSPD1, IL8
20citrate449.5HSPD1, CD79A, LTF
21salbutamol44 50 28 24 1113.5CD79A, IL8
22polymyxin b449.5HSPD1, IL8, LTF
23indomethacin44 28 61 1112.4HSPD1, LTF, CD79A
24polysaccharide449.4CD79A, HSPD1, LTF
25rantes449.4DEFB4A, HSPD1, IL8
26n-formylmethionyl-leucylphenylalanine449.4IL8, LTF
27fibrinogen449.4CD79A, LTF, HSPD1
28clarithromycin44 1110.3LTF, IL8, CD79A
29pd 98,059449.3IL8, DEFB4A, HSPD1
30methacholine44 50 1111.3CD79A, LTF, IL8
31neopterin449.3CD79A, IL8, LTF
32hyaluronic acid44 2410.3IL8, LTF, CD79A
33mannose449.2HSPD1, DEFB4A, LTF, CD79A
34peptidoglycan44 2810.1IL8, DEFB4A
35paraffin449.1HSPD1, CD79A, LTF, DEFB4A
36hbd2449.1DEFA5, IL8, DEFB4A
37endotoxin449.1LTF, DEFB4A, IL8, HSPD1
38retinoic acid44 2410.0HSPD1, CD79A, LTF, DEFB4A
39pge2449.0LTF, CD79A, IL8
40lactate449.0CD79A, IL8, HSPD1
41n acetylcysteine448.9CD79A, LTF, HSPD1, IL8
42superoxide44 249.9LTF, IL8, HSPD1
43cyclosporin a44 28 6110.9LTF, IL8, HSPD1, CD79A
44h2o2448.9CD79A, IL8, HSPD1, LTF
45histamine44 28 2410.9IL8, DEFB4A, CD79A, LTF
46heparin44 28 24 1111.9DEFB4A, IL8, LTF, CD79A
47vegf448.9IL8, CD79A, HSPD1, LTF
48estrogen448.6LTF, PHB2, CD79A, DEFB4A, HSPD1
49dexamethasone44 50 28 1111.5HSPD1, CD79A, IL8, LTF, DEFB4A
50cysteine448.5DEFB4A, HSPD1, IL8, CD79A, LTF

GO Terms for genes affiliated with Urethritis

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Cellular components related to Urethritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301419.3LTF, HSPD1
2Golgi lumenGO:0057969.2DEFA5, DEFB4A
3extracellular spaceGO:0056158.2HSPD1, DEFA5, IL8, LTF
4extracellular regionGO:0055768.1LTF, DEFB4A, DEFA5, IL8

Biological processes related to Urethritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1B cell activationGO:0421139.5CD79A, HSPD1
2chemotaxisGO:0069359.4IL8, DEFB4A
3B cell proliferationGO:0421009.3CD79A, HSPD1
4antibacterial humoral responseGO:0197319.2LTF, DEFA5

Products for genes affiliated with Urethritis

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  • Antibodies
  • Proteins
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Sources for Urethritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet