MCID: URN001
MIFTS: 21

Urinary Bladder Small Cell Neuroendocrine Carcinoma malady

Categories: Cancer diseases, Respiratory diseases, Neuronal diseases, Nephrological diseases

Aliases & Classifications for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Aliases & Descriptions for Urinary Bladder Small Cell Neuroendocrine Carcinoma:

Name: Urinary Bladder Small Cell Neuroendocrine Carcinoma 12 14
Small Cell Neuroendocrine Carcinoma of the Urinary Bladder 12
Small Cell/neuroendocrine Carcinoma of Urinary Bladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7132
NCIt 47 C9461
UMLS 69 C1332564

Summaries for Urinary Bladder Small Cell Neuroendocrine Carcinoma

MalaCards based summary : Urinary Bladder Small Cell Neuroendocrine Carcinoma, also known as small cell neuroendocrine carcinoma of the urinary bladder, is related to small cell neuroendocrine carcinoma and progressive relapsing multiple sclerosis. An important gene associated with Urinary Bladder Small Cell Neuroendocrine Carcinoma is CHGA (Chromogranin A). The drugs Paclitaxel and nivolumab have been mentioned in the context of this disorder.

Related Diseases for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Diseases related to Urinary Bladder Small Cell Neuroendocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
id Related Disease Score Top Affiliating Genes
1 small cell neuroendocrine carcinoma 10.2
2 progressive relapsing multiple sclerosis 10.1 CHGA GRP
3 peroneal nerve paralysis 10.1 CHGA SYP
4 brain stem ependymoma 10.1 CHGA SYP
5 non specific chronic endometritis 10.1 CHGA SYP
6 extrahepatic biliary papillomatosis 10.1 CHGA SYP
7 epithelioid malignant peripheral nerve sheath tumor 10.1 CHGA SYP
8 cartilage cancer 10.1 CHGA SYP
9 villous adenocarcinoma 10.1 CHGA SYP
10 jejunal neuroendocrine tumor 10.1 CHGA SYP
11 renal pelvis adenocarcinoma 10.1 CHGA SYP
12 barre-lieou syndrome 10.1 CHGA SYP
13 microinvasive cervical squamous cell carcinoma 10.1 CHGA SYP
14 gastric duplication cysts 10.1 CHGA SYP
15 diffuse cutaneous mastocytosis 10.1 CHGA SYP
16 main bronchus cancer 10.1 CHGA SYP
17 cavernous hemangioma of face 10.1 CHGA SYP
18 adult botryoid rhabdomyosarcoma 10.1 CHGA SYP
19 exudative glomerulonephritis 10.1 CHGA SYP
20 hepatorenal syndrome 10.1 CHGA SYP
21 acalculous cholecystitis 10.1 CHGA SYP
22 brain stem astrocytic neoplasm 10.1 CHGA SYP
23 calcific tendinitis 10.1 CHGA SYP
24 mitochondrial complex ii deficiency 10.1 CHGA SYP
25 bone marrow cancer 10.1 CHGA SYP
26 dysgerminoma of ovary 10.1 CHGA SYP
27 acinar cell cystadenocarcinoma 10.1 CHGA SYP
28 cowden syndrome 3 10.1 CHGA SYP
29 thymus squamous cell carcinoma 10.1 CHGA SYP
30 testicular trophoblastic tumor 10.1 CHGA SYP
31 bone dysplasia azouz type 10.1 CHGA SYP
32 pancreatic agenesis 10.1 CHGA SYP
33 vaginal villous adenoma 10.1 CHGA SYP
34 t-cell adult acute lymphocytic leukemia 10.1 CHGA SYP
35 inner ear cancer 10.1 CHGA SYP
36 struma ovarii 10.0 CHGA SYP
37 urinary tract papillary transitional cell benign neoplasm 10.0 CHGA SYP
38 sm-ahnmd 10.0 CHGA ENO2
39 cavernous hemangioma of colon 10.0 ENO2 GRP
40 peeling skin syndrome 10.0 CHGA SYP
41 granulocytopenia 10.0 CHGA ENO2
42 parietal lobe neoplasm 10.0 CHGA ENO2
43 urinary tract obstruction 10.0 CHGA ENO2
44 glioma susceptibility 1 10.0 CHGA SYP
45 spinal stenosis 10.0 CHGA ENO2
46 gastrointestinal system benign neoplasm 10.0 CHGA ENO2
47 infiltrating renal pelvis transitional cell carcinoma 10.0 ENO2 SYP
48 adult medulloblastoma 10.0 CHGA GRP
49 skeletal-extraskeletal angiomatosis 10.0 ENO2 SYP
50 glomus tumor 10.0 ENO2 SYP

Graphical network of the top 20 diseases related to Urinary Bladder Small Cell Neuroendocrine Carcinoma:



Diseases related to Urinary Bladder Small Cell Neuroendocrine Carcinoma

Symptoms & Phenotypes for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Drugs & Therapeutics for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Drugs for Urinary Bladder Small Cell Neuroendocrine Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 1, Phase 2 33069-62-4 36314
2
nivolumab Approved Phase 2,Phase 1 946414-94-4
3 Interleukin-2 Phase 1, Phase 2
4 Analgesics Phase 1, Phase 2
5 Albumin-Bound Paclitaxel Phase 1, Phase 2
6 Analgesics, Non-Narcotic Phase 1, Phase 2
7 Peripheral Nervous System Agents Phase 1, Phase 2
8 Immunoglobulins Phase 1, Phase 2
9 Antibodies, Monoclonal Phase 1, Phase 2
10 Antibodies Phase 1, Phase 2
11 Antimitotic Agents Phase 1, Phase 2
12 Antineoplastic Agents, Phytogenic Phase 1, Phase 2
13
Carboplatin Approved Phase 1 41575-94-4 10339178 498142 38904
14
Gemcitabine Approved Phase 1 95058-81-4 60750
15
Trastuzumab Approved, Investigational Phase 1 180288-69-1 9903
16
Lenograstim Approved Phase 1 135968-09-1
17
Diazepam Approved, Illicit, Vet_approved Phase 1 439-14-5 3016
18
Acetaminophen Approved Phase 1 103-90-2 1983
19
Diphenhydramine Approved Phase 1 58-73-1, 147-24-0 3100
20
Promethazine Approved Phase 1 60-87-7 4927
21
Azacitidine Approved, Investigational Phase 1 320-67-2 9444
22
Docetaxel Approved May 1996, Investigational Phase 1 114977-28-5 148124 9877265
23 Adjuvants, Immunologic Phase 1
24 Angiogenesis Inhibitors Phase 1
25 Angiogenesis Modulating Agents Phase 1
26 Anti-Infective Agents Phase 1
27 Immunosuppressive Agents Phase 1
28 Interleukin-12 Phase 1
29 Antimetabolites Phase 1
30 Antimetabolites, Antineoplastic Phase 1
31 Antiviral Agents Phase 1
32 interferons Phase 1
33 Vaccines Phase 1
34 Poly ICLC Phase 1
35 Interferon Inducers Phase 1
36 Cola Nutraceutical Phase 1

Interventional clinical trials:

(show all 11)
id Name Status NCT ID Phase
1 Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients Unknown status NCT01134250 Phase 1, Phase 2
2 Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium Recruiting NCT00756639 Phase 2
3 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
4 Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors Completed NCT00014456 Phase 1
5 Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu Completed NCT00004074 Phase 1
6 A Personalized Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder Cancer Recruiting NCT02897765 Phase 1
7 Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies Recruiting NCT02223052 Phase 1
8 TAA-Specific CTLS for Solid Tumors (TACTASOM) Recruiting NCT02239861 Phase 1
9 Phase 1/1b Study to Evaluate the Safety and Tolerability of CPI-444 Alone and in Combination With Atezolizumab in Advanced Cancers Recruiting NCT02655822 Phase 1
10 Cone Beam CT Scanning in Lung and Bladder Cancer. Completed NCT00469066
11 Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer Recruiting NCT03154190

Search NIH Clinical Center for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Genetic Tests for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Anatomical Context for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Publications for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Variations for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Cosmic variations for Urinary Bladder Small Cell Neuroendocrine Carcinoma:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM550 KRAS urinary tract,bladder,carcinoma,undifferentiated carcinoma c.181C>G p.Q61E 8

Expression for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Search GEO for disease gene expression data for Urinary Bladder Small Cell Neuroendocrine Carcinoma.

Pathways for Urinary Bladder Small Cell Neuroendocrine Carcinoma

GO Terms for Urinary Bladder Small Cell Neuroendocrine Carcinoma

Biological processes related to Urinary Bladder Small Cell Neuroendocrine Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway GO:1900738 8.62 CHGA GRP

Sources for Urinary Bladder Small Cell Neuroendocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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