MCID: URN003
MIFTS: 50

Urinary Schistosomiasis malady

Nephrological diseases, Blood diseases categories

Aliases & Classifications for Urinary Schistosomiasis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 27ICD9CM, 55SNOMED-CT, 38NCIt, 33MeSH
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Urinary Schistosomiasis, Aliases & Descriptions:

Name: Urinary Schistosomiasis 9 11 60
Schistosoma Hematobium Infection 9 60
Schistosomiasis Due to Schistosoma Haematobium 9
Schistosoma Hematobium Infectious Disease 9
Vesical Schistosomiasis Nos 9
 
Cystitis with Bilharziasis 9
Schistosomiasis of Bladder 9
Schistosoma Haematobium 9
Bladder Schistosomiasis 9
Schistosomiasis Urinary 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases, Blood diseases


External Ids:

Disease Ontology9 DOID:1394
ICD9CM27 120.0
MeSH33 D012553

Summaries for Urinary Schistosomiasis

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Disease Ontology:9 A schistosomiasis that involves parasitic infection of the urinary tract caused by a digenetic trematode schistosoma haematobium causing cystitis, ureteritis, fibrosis of the bladder and haematuria, which can progress to bladder cancer.

MalaCards based summary: Urinary Schistosomiasis, also known as schistosoma hematobium infection, is related to schistosomiasis and onchocerciasis. An important gene associated with Urinary Schistosomiasis is EPX (eosinophil peroxidase), and among its related pathways are IL-4 Signaling and its Primary Biological Effects in Different Immune Cell Types and IL12 signaling mediated by STAT4. The compounds ltc4 and tele-methylhistamine have been mentioned in the context of this disorder. Affiliated tissues include testes, kidney and colon, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Wikipedia:63 Schistosoma haematobium is an important digenetic trematode, and is found in Africa and the Middle East.... more...

Related Diseases for Urinary Schistosomiasis

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Diseases related to Urinary Schistosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1schistosomiasis32.5IL5, IL13
2onchocerciasis30.7EPX, RNASE3, IL5
3malaria30.5IL10, IFNG
4plasmodium falciparum malaria30.4IFNG, IL10
5hepatitis b30.0CTLA4, IL10, IFNG
6hepatitis c29.7IL10, IFNG, CTLA4, IL4
7atopy28.8IGHE, RNASE3, CTLA4, IL13, IL10, IL5
8proteinuria10.5
9chronic rhinitis10.5RNASE3
10eosinophilic fasciitis10.5IL5
11bronchitis10.5RNASE3
12collagenous colitis10.5RNASE3
13aspergillosis10.4IFNG
14eosinophilia-myalgia syndrome10.4IL5
15esophagitis, eosinophilic, 110.4IL5
16neuroschistosomiasis10.4
17periapical granuloma10.4IL4
18eczema herpeticum10.4IGHE
19proctitis10.4RNASE3, EPX
20thyroiditis10.3CTLA4
21chronic eosinophilic pneumonia10.3IL5, RNASE3
22conjunctivitis10.3IGHE, RNASE3
23giant papillary conjunctivitis10.3IL5, RNASE3
24bacteriuria10.3
25churg-strauss syndrome10.3RNASE3, IL5
26anisakiasis10.3RNASE3, IGHE
27toxocariasis10.3IGHE, RNASE3
28paragonimiasis10.3IL5, IGHE
29strongyloidiasis10.3IL5, IGHE
30endomyocardial fibrosis10.3
31cerebritis10.3
32intestinal schistosomiasis10.3
33bladder neck obstruction10.3
34adenocarcinoma10.3
35dacryoadenitis10.3
36prostate adenocarcinoma10.3
37prostatitis10.3
38vaginal discharge10.3
39vaginitis10.3
40splenomegaly10.3
41epididymitis10.3
42intraocular lymphoma10.2IL10
43hepatitis10.2
44eosinophilic gastroenteritis10.2IGHE, IL5
45esophagitis10.2IL5, IL13
46keratoconjunctivitis10.2IL13, RNASE3, IL5
47bronchiectasis10.2IGHE, RNASE3
48contact dermatitis10.2IL5, IGHE
49otitis media10.2RNASE3, IGHE
50immunodeficiency, x-linked, with hyper-igm10.2IL4, IGHE

Graphical network of the top 20 diseases related to Urinary Schistosomiasis:



Diseases related to urinary schistosomiasis

Symptoms for Urinary Schistosomiasis

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Drugs & Therapeutics for Urinary Schistosomiasis

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Drug clinical trials:

Search ClinicalTrials for Urinary Schistosomiasis

Search NIH Clinical Center for Urinary Schistosomiasis

Genetic Tests for Urinary Schistosomiasis

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Anatomical Context for Urinary Schistosomiasis

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MalaCards organs/tissues related to Urinary Schistosomiasis:

31
Testes, Kidney, Colon, Skin, Neutrophil

Animal Models for Urinary Schistosomiasis or affiliated genes

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MGI Mouse Phenotypes related to Urinary Schistosomiasis:

35 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6IL10, IL5, IFNG, STAT6
2MP:00053708.0STAT6, IFNG, IL4, IL5, IL10, CTLA4
3MP:00053817.9IFNG, IL4, IL5, IL10, IL13, CTLA4
4MP:00053797.8STAT6, IFNG, IL4, IL10, IL13, CTLA4
5MP:00107717.7STAT6, IFNG, IL4, IL10, IL13, CTLA4
6MP:00053887.6STAT6, IFNG, IL4, IL5, IL10, IL13
7MP:00053897.5STAT6, IFNG, IL4, IL5, IL10, IL13
8MP:00030127.3IGHE, IFNG, IL4, IL10, IL13, ARAP2
9MP:00053766.7IGHE, STAT6, IFNG, IL4, IL5, IL10
10MP:00053976.6CTLA4, IGHE, EPX, STAT6, IFNG, IL4
11MP:00053876.6IGHE, EPX, STAT6, IFNG, IL4, IL5

Publications for Urinary Schistosomiasis

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Articles related to Urinary Schistosomiasis:

(show top 50)    (show all 334)
idTitleAuthorsYear
1
Spatial distribution of urinary schistosomiasis in Cross River State, Nigeria using geographical information system and school based questionnaire. (24506017)
2013
2
Prevalence of urinary schistosomiasis in school-aged children in Langai, Plateau State: pre- and post-intervention. (23311180)
2012
3
Proportion of Urinary Schistosomiasis among HIV-Infected Subjects in Benin City, Nigeria. (22043410)
2011
4
Urinary Schistosomiasis around Oyan Reservoir, Nigeria: Twenty Years after the First Outbreak. (23112995)
2010
5
Use of circulating cathodic antigen strips for the diagnosis of urinary schistosomiasis. (18951599)
2009
6
Age and gender effects in self-reported urinary schistosomiasis in Tanzania. (18419586)
2008
7
School-based control of urinary schistosomiasis on Zanzibar, Tanzania: monitoring micro-haematuria with reagent strips as a rapid urological assessment. (18947774)
2007
8
Cystoscopy in the diagnosis and follow-up of urinary schistosomiasis in Brazilian soldiers returning from Mozambique, Africa. (16547578)
2006
9
Use of circulating cathodic antigen (CCA) dipsticks for detection of intestinal and urinary schistosomiasis. (16386231)
2006
10
Applicability of a monoclonal antibody-based dipstick in diagnosis of urinary schistosomiasis in the Central Region of Ghana. (15361112)
2004
11
Urinary schistosomiasis in Zimbabwean school children: predictors of morbidity. (15477190)
2004
12
Diagnosis of urinary schistosomiasis: a novel approach to compare bladder pathology measured by ultrasound and three methods for hematuria detection. (15238697)
2004
13
Efficacy of artesunate in the treatment of urinary schistosomiasis, in an endemic community in Nigeria. (15257799)
2004
14
Urinary schistosomiasis in schoolchildren on Zanzibar Island (Unguja), Tanzania: a parasitological survey supplemented with questionnaires. (12474477)
2002
15
Prevalence and morbidity of urinary schistosomiasis among schoolchildren in the Mwera division of Pangani district, Tanzania, 30 months after the last round of annual, selective treatments. (12625941)
2002
16
Prevalence and intensity of urinary schistosomiasis in primary school children of the Kotto Barombi Health Area, Cameroon. (12002103)
2001
17
Impact of urinary schistosomiasis on rural land use: empirical evidence from Nigeria. (11144785)
2001
18
Urinary schistosomiasis in schoolchildren in Dar-es-Salaam, Tanzania, and the factors influencing its transmission. (11784423)
2001
19
Recent urban growth and urinary schistosomiasis in Niamey, Niger. (10929143)
2000
20
Urinary schistosomiasis among schoolchildren in Ibadan, an urban community in south-western Nigeria. (10320657)
1999
21
A monoclonal antibody-based dipstick assay for diagnosis of urinary schistosomiasis. (9463666)
1997
22
The use of questionnaires for the identification of high risk areas for urinary schistosomiasis: the Ethiopian experience. (8840611)
1996
23
Urinary schistosomiasis in rural communities of some local government areas in Plateau State, Nigeria: a preliminary parasitological and malacological survey. (8960195)
1996
24
Limited field evaluation of a rapid monoclonal antibody-based dipstick assay for urinary schistosomiasis. (8985756)
1996
25
Identification and characterization of Schistosoma mansoni antigens recognized by T and B lymphocytes of humans with early active intestinal and/or urinary schistosomiasis. (7541026)
1995
26
Prevalence and severity of urinary schistosomiasis in Ibadan, Nigeria. (8904071)
1995
27
Urinary schistosomiasis in Nebraska. (7566250)
1995
28
Urinary schistosomiasis in childhood. (8073544)
1994
29
Egg viability in urinary schistosomiasis. II. Simplifying modifications and standardization of new methods. (7681485)
1993
30
Egg viability in urinary schistosomiasis. I. New methods compared with available methods. (7679149)
1993
31
Urinary schistosomiasis in the Sichili Health Zone, Western Province, Zambia. (1801143)
1991
32
Metrifonate in the control of urinary schistosomiasis in Zanzibar. (2127381)
1990
33
To wash or not to wash (Nytrel filters and urinary Schistosomiasis). (15463042)
1988
34
Efficacy of metrifonate in a highly endemic area of urinary schistosomiasis in Kenya. (3124647)
1988
35
Chronic urinary schistosomiasis: patterns of abnormalities in radionuclide Tc-99 m DTPA diuretic renogram. (3140850)
1988
36
Urinalysis reagent strips in the screening of children for urinary schistosomiasis in the RSA. (3116682)
1987
37
Ultrasonographical aspects of urinary schistosomiasis: assessment of morphological lesions in the upper and lower urinary tract. (3085056)
1986
38
Urinary schistosomiasis acquired in Mali, West Africa. I. Case report of Schistosoma haematobium infection in a Sri Lankan with a note on the parasitic life cycle and the risk of local transmission. (3109751)
1986
39
Effect of praziquantel on hematuria and proteinuria in urinary schistosomiasis. (3938926)
1985
40
Single dose oral treatment in urinary schistosomiasis: a double blind trial. (6401550)
1983
41
The effect of metrifonate on hookworm infections in Kenyan children treated for urinary schistosomiasis. A preliminary report. (6892236)
1982
42
Malumfashi Endemic Diseases Research Project, VI. Urinary schistosomiasis: abnormal urograms in infected males from the Malumfashi study area, northern Nigeria. (496461)
1979
43
Manifestations of urinary schistosomiasis in a British provincial city. (5162609)
1971
44
Calcification of the bladder in urinary schistosomiasis. (5485619)
1970
45
II. Fractionation of the antigen of Fasciola gigantica by salting out with reference to the use of the isolated fractions as skin test antigens in cases of urinary schistosomiasis. (5726942)
1968
46
Steroid therapy in chronic urinary schistosomiasis (bilharziasis). (6050892)
1967
47
Urinary schistosomiasis. A case report. (5594207)
1967
48
Urinary Schistosomiasis in Ibadan school-children. (14036619)
1962
49
Urinary schistosomiasis: report of a case in a Canadian soldier. (13511306)
1958
50
The test of cure in urinary schistosomiasis. (13422576)
1957

Variations for Urinary Schistosomiasis

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Expression for genes affiliated with Urinary Schistosomiasis

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Search GEO for disease gene expression data for Urinary Schistosomiasis.

Pathways for genes affiliated with Urinary Schistosomiasis

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Pathways related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7STAT6, IL4
29.5IFNG, IL13
39.3IL10, IFNG
4
Show member pathways
9.3IL10, IFNG
59.2IL13, IL5, IL4
6
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway58
9.1IL4, IFNG, STAT6
7
Show member pathways
Immune response IL 12 induced IFN gamma production58
9.1STAT6, IFNG, IL4
8
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.0IL10, IFNG, STAT6
9
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.0IL10, IFNG, STAT6
109.0IFNG, IL4, IL5
11
Show member pathways
Development IGF RI signaling
Immune response IL 4 signaling pathway58
Signal transduction AKT signaling58
8.9IL4, STAT6, IGHE
12
Show member pathways
8.7IL13, IL10, IL5, IL4
13
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
8.6IFNG, IL4, IL5, CTLA4
148.6IFNG, IL4, IL5, IL13
15
Show member pathways
Immune response BCR pathway58
Fc-epsilon receptor I signaling in mast cells36
8.4IGHE, IL4, IL5, IL13
16
Show member pathways
8.4STAT6, IL4, IL5, IL10, IL13
17
Show member pathways
8.4STAT6, IL4, IL5, IL10, IL13
18
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.1IFNG, IL4, IL5, IL10, CTLA4
198.1IFNG, IL4, IL5, IL10, IL13
208.1IFNG, IL4, IL5, IL10, IL13
218.1IFNG, IL4, IL5, IL10, IL13
22
Show member pathways
8.1IL13, IL10, IL5, IL4, IFNG
237.9IGHE, STAT6, IL4, IL5, IL10
24
Show member pathways
7.8STAT6, IFNG, IL4, IL5, IL10, IL13
25
Show member pathways
Type III interferon signaling36
7.8STAT6, IFNG, IL4, IL5, IL10, IL13
26
Show member pathways
7.8IL13, IL10, IL5, IL4, IFNG, STAT6
27
Show member pathways
7.2CTLA4, RNASE3, EPX, IFNG, IL4, IL5

Compounds for genes affiliated with Urinary Schistosomiasis

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Compounds related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

(show top 50)    (show all 156)
idCompoundScoreTop Affiliating Genes
1ltc4439.3EPX, IL5, RNASE3, IL13
2tele-methylhistamine439.1RNASE3, EPX, IGHE
3salmeterol43 49 28 1212.1IL5, EPX, IL13, RNASE3, IL4
4sodium cromoglycate439.0RNASE3, IL5, EPX, IGHE
5cetirizine43 28 24 1212.0EPX, RNASE3, IL5, IGHE
6ketotifen43 1210.0EPX, RNASE3, IL5, IGHE
7unicap438.9IL5, RNASE3, IGHE
8betaseron438.9IFNG, IL4, IL10
9theophylline43 28 24 1211.9RNASE3, IL13, IL10, IL5, EPX
10amphotericin b438.9IL4, IL13, IL5, IFNG
11alpha-galactosylceramide438.9IFNG, IL13, IL10, IL4
12nedocromil sodium438.8IGHE, RNASE3, IL4, IL5
13indoleamine438.8IL10, IFNG, IL13, CTLA4
14omalizumab43 129.8IL4, IL5, IGHE, IL13
15ovomucoid438.8IL5, IL4, IGHE, IL13
16azelastine43 129.8RNASE3, IL4, IL5, IGHE
17pgd2438.7IL5, IGHE, RNASE3, EPX, IL13
18polyinosinic-polycytidylic acid438.6IL5, IL4, IFNG, IL10
19interferon gamma438.6IFNG, IL4, IL10
20con a438.5IL10, IL5, CTLA4, IFNG, IL4
21il-12438.5IL4, IL10, IFNG, IL5, IL13
22gm-csf43 289.5IFNG, IL13, IL10, IL4, IL5
23methacholine43 49 1210.5IGHE, RNASE3, IL13, IL4, IL5
24thalidomide43 49 59 1211.5CTLA4, IL13, IFNG, IL5, IL10
25rolipram43 59 2810.3IL13, IL4, IL5, IFNG, EPX, IL10
26salbutamol43 49 28 24 1212.2RNASE3, IGHE, IL13, EPX, IL5, IL10
27glatiramer acetate43 129.2IFNG, IL4, IL5, CTLA4, IL10, IL13
28il 10438.2IL4, IFNG, CTLA4, IL5, IL10, IL13
29tacrolimus43 49 1210.1IL10, IL5, IFNG, IL4, IL13, CTLA4
30infliximab43 49 1210.1CTLA4, IL10, IFNG, IL4, IGHE
31montelukast43 49 28 1211.0IL10, IL4, RNASE3, IGHE, IL13, IL5
32thyroxine43 249.0IL4, IL5, IL10, IL13, IGHE
33praziquantel43 129.0IL13, IL10, IL5, IL4, RNASE3, IGHE
34sb 20358043 599.0IL13, IL10, IL5, IL4, IFNG, STAT6
35ivig438.0IFNG, IGHE, IL4, IL5, IL10
36rantes437.8IL13, IL10, IL4, IFNG, CTLA4, IL5
37pge2437.8IL10, IFNG, IL4, EPX, IL5, RNASE3
38ionomycin437.8IL13, CTLA4, IL5, IFNG, IL10, IL4
39tarc437.7IL5, IL10, IL13, IFNG, IGHE, IL4
40budesonide43 49 129.7IL5, IL4, IFNG, EPX, RNASE3, IL13
41hydrocortisone43 2 59 1210.7IL5, IFNG, IL4, IL10, IGHE, IL13
42thymidine43 248.6IL5, IFNG, IL4, CTLA4, IL13, IL10
43fluticasone propionate43 49 59 1210.6IL13, IL5, IL4, RNASE3, IGHE, STAT6
44prednisolone43 28 129.6IL10, IGHE, IFNG, EPX, RNASE3, IL13
45cycloheximide437.2IL13, IL10, IL4, IFNG, STAT6, IGHE
46vegf437.1IL10, IL5, IL4, IFNG, IGHE, IL13
47cyclosporin a43 28 599.0RNASE3, IGHE, IL5, IL10, CTLA4, IL13
48histamine43 28 248.8IL5, IL4, IFNG, STAT6, EPX, RNASE3
49allergens436.5CTLA4, IL4, IFNG, IGHE, RNASE3, EPX
50dexamethasone43 49 28 129.5IL4, IL13, STAT6, EPX, RNASE3, IFNG

GO Terms for genes affiliated with Urinary Schistosomiasis

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Cellular components related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.6CTLA4, IL13, IL4, IFNG
2extracellular regionGO:00055767.9IL13, IL5, IFNG, RNASE3, IGHE
3extracellular spaceGO:00056157.8IFNG, IL4, IL5, IL10, IL13

Biological processes related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1T-helper 1 cell lineage commitmentGO:000229610.0IL4, STAT6
2positive regulation of isotype switching to IgE isotypesGO:004829510.0STAT6, IL4
3regulation of proton transportGO:00101559.9IL13, IL4
4regulation of isotype switchingGO:00451919.8IL4, IL10
5type 2 immune responseGO:00420929.8IL10, IL4
6negative regulation of B cell proliferationGO:00308899.8IL10, CTLA4
7negative regulation of nitric oxide biosynthetic processGO:00450199.7IL10, IL4
8negative regulation of T cell proliferationGO:00421309.7IL10, CTLA4
9positive regulation of isotype switching to IgG isotypesGO:00483049.7IFNG, IL4
10positive regulation of chemokine biosynthetic processGO:00450809.6IFNG, IL4
11positive regulation of B cell proliferationGO:00308909.6IL13, IL5, IL4
12defense response to protozoanGO:00428329.5IL4, IFNG
13negative regulation of growth of symbiont in hostGO:00441309.5IFNG, IL10
14positive regulation of T cell proliferationGO:00421029.4IL4, IFNG
15positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.3IL10, IL5, IL4
16defense response to bacteriumGO:00427429.3IL10, IFNG, RNASE3
17positive regulation of MHC class II biosynthetic processGO:00453489.2IL10, IL4, IFNG
18inflammatory responseGO:00069548.9IL13, IL10, IL5
19response to drugGO:00424938.8IFNG, IL4, IL10
20positive regulation of transcription from RNA polymerase II promoterGO:00459448.6IL10, IL4, IFNG, STAT6
21immune responseGO:00069558.4IGHE, IL4, IL5, IL13, CTLA4

Molecular functions related to Urinary Schistosomiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth factor activityGO:00080839.1IL10, IL5, IL4
2cytokine activityGO:00051257.8IL13, IL10, IL5, IL4, IFNG

Products for genes affiliated with Urinary Schistosomiasis

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Sources for Urinary Schistosomiasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet