MCID: URN009
MIFTS: 58

Urinary System Disease

Categories: Nephrological diseases

Aliases & Classifications for Urinary System Disease

MalaCards integrated aliases for Urinary System Disease:

Name: Urinary System Disease 12 14
Congenital Malformation of the Urinary System 69
Non-Neoplastic Urinary System Disorder 69
Non-Neoplastic Urinary Tract Disease 12
Abnormality of the Urinary System 28
Urinary Tract Diseases 51
Urinary Tract Disease 12
Urinary Tract Anomaly 51
Urologic Diseases 69

Classifications:



External Ids:

Disease Ontology 12 DOID:18
NCIt 46 C27599

Summaries for Urinary System Disease

Disease Ontology : 12 A disease of anatomical entity that is located in kidney, ureter, bladder and urethra.

MalaCards based summary : Urinary System Disease, also known as congenital malformation of the urinary system, is related to bladder disease and kidney disease, and has symptoms including urologic problem, other and unspecified genitourinary symptoms and renal pain. An important gene associated with Urinary System Disease is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways is Osteoblast Signaling. The drugs Nitrofurantoin and Trimethoprim have been mentioned in the context of this disorder. Affiliated tissues include kidney, kidney and heart, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 72 The urinary system, also known as the renal system, consists of the kidneys, ureters, bladder, and the... more...

Related Diseases for Urinary System Disease

Diseases related to Urinary System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 bladder disease 32.1 CRP KLK3 TRPV1
2 kidney disease 31.0 ACE ALB B2M CST3 EPO FGF23
3 vesicoureteral reflux 1 30.8 NAGLU REN UMOD
4 acute pyelonephritis 30.6 ALB CRP NAGLU
5 pyelonephritis 30.4 ACE ALB CRP NAGLU UMOD
6 heart disease 30.2 ACE ALB CRP CST3 REN
7 exstrophy of bladder 10.9
8 chromosome 6q11-q14 deletion syndrome 10.9
9 hyporeninemic hypoaldosteronism 10.8 ACE REN
10 alpha-thalassemia 10.8
11 cork-handlers' disease 10.8 ALB CD79A
12 ostertagiasis 10.8 ALB CD79A
13 dermatitis, atopic, 3 10.8 ALB CD79A
14 familial idiopathic steroid-resistant nephrotic syndrome with minimal changes 10.8 NPHS1 NPHS2
15 diffuse glomerulonephritis 10.8 ALB B2M CD79A
16 non-secretory myeloma 10.8 ALB B2M CD79A
17 renal artery obstruction 10.8 ACE REN
18 anuria 10.7 ACE ALB REN
19 acute kidney tubular necrosis 10.7 ALB NAGLU UMOD
20 chronic pyelonephritis 10.7 B2M PKDREJ UMOD
21 immunodeficiency 43 10.7 ALB B2M
22 hypertensive nephropathy 10.7 ACE ALB NAGLU
23 urethral syndrome 10.7
24 bacteriuria 10.7
25 ureteral disease 10.7
26 lower urinary tract calculus 10.7
27 autoimmune disease of urogenital tract 10.7 ALB CD79A TLR9
28 uremic neuropathy 10.7 B2M EPO PTH
29 mature b-cell neoplasm 10.7 B2M CD79A TLR9
30 renal artery disease 10.7 ACE EPO REN
31 keratoconjunctivitis sicca 10.7 ALB CD79A TLR9
32 hypersensitivity reaction type iv disease 10.7 ACE CD79A TLR9
33 hydronephrosis 10.7 ALB B2M NAGLU
34 benign essential hypertension 10.7 ALB REN
35 hypertension, diastolic 10.7 ACE REN
36 amyloid tumor 10.7 B2M CD79A PKDREJ
37 nasal cavity disease 10.7 CD79A TLR9 TRPV1
38 sclerosing keratitis 10.7 B2M CD79A
39 human immunodeficiency virus infectious disease 10.7 B2M CD79A TLR9
40 calciphylaxis 10.7 ALB FGF23 PTH
41 pure autonomic failure 10.7 ACE EPO REN
42 hemorrhagic fever with renal syndrome 10.7 ALB B2M CRP
43 nose disease 10.7 CD79A TLR9 TRPV1
44 acute cystitis 10.7 ALB CRP KLK3
45 seminal vesicle adenocarcinoma 10.7 KLK3 KRT20
46 stomach disease 10.7 CD79A TLR9 TRPV1
47 kidney hypertrophy 10.7 ALB NPHS1 NPHS2
48 upper respiratory tract disease 10.7 CD79A TLR9 TRPV1
49 membranoproliferative glomerulonephritis 10.7 ALB CD79A NPHS1
50 parathyroid gland disease 10.7 ALB FGF23 PTH

Graphical network of the top 20 diseases related to Urinary System Disease:



Diseases related to Urinary System Disease

Symptoms & Phenotypes for Urinary System Disease

UMLS symptoms related to Urinary System Disease:


urologic problem, other and unspecified genitourinary symptoms, renal pain, bladder discomfort, uti symptoms, burning urination, urinary tenesmus, difficulty passing urine, flank tenderness, ureteral pain, loin pain, urethral burning on micturition, renal colic, pain in urethra, urgency of micturition, polyuria, dysuria

MGI Mouse Phenotypes related to Urinary System Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.2 NPHS1 NPHS2 CD79A PTH CRP CST3
2 cardiovascular system MP:0005385 10.15 B2M NPHS2 PTH CRP CST3 REN
3 immune system MP:0005387 10.07 B2M CD79A PTH CRP REN EPO
4 mortality/aging MP:0010768 9.77 B2M NPHS1 NPHS2 PTH CST3 REN
5 liver/biliary system MP:0005370 9.7 B2M CD79A EPO ACE ALB NAGLU
6 renal/urinary system MP:0005367 9.4 NPHS1 NPHS2 CD79A REN ACE FGF23

Drugs & Therapeutics for Urinary System Disease

Drugs for Urinary System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1519)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 67-20-9 5353830
2
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 738-70-5 5578
3
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 104987-11-3 445643 439492
4
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 100986-85-4 149096
5
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 82419-36-1 4583
6
Pitavastatin Approved Phase 4,Phase 1 147511-69-1, 147526-32-7 5282452 6366718
7
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 159351-69-6 6442177
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
9
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53123-88-9 46835353 6436030 5284616
10
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 616-91-1 12035
11
Daclizumab Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 152923-56-3
12
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
13
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
14
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
15
alemtuzumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216503-57-0
16
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
17
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 75847-73-3 40466924 5362032
18
Enalaprilat Approved Phase 4,Phase 3,Phase 2,Phase 1 76420-72-9 6917719
19
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
20
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 76-42-6 5284603
21
Perindopril Approved Phase 4 107133-36-8, 82834-16-0 107807
22
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137862-53-4 60846
23
Piperacillin Approved Phase 4,Phase 2,Phase 3 66258-76-2 43672
24
Sulbactam Approved Phase 4,Phase 3,Phase 2,Phase 1 68373-14-8
25
Cefotaxime Approved Phase 4 63527-52-6 5742673 456256
26
Cefoxitin Approved Phase 4 35607-66-0 441199
27
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
28
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 54-31-9 3440
29
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-93-5 3639
30
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 46507594 772
31
Basiliximab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 179045-86-4, 152923-56-3
32
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
33
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
34
Spironolactone Approved Phase 4,Phase 2,Phase 3,Phase 1 1952-01-7, 52-01-7 5833
35
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
36
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1 81-81-2 54678486 6691
37
Ursodeoxycholic acid Approved, Investigational Phase 4,Phase 2 128-13-2 31401
38
Digoxin Approved Phase 4 20830-75-5 2724385 30322
39
Pirfenidone Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53179-13-8 40632
40
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 76631-46-4, 113775-47-6 5311068 56032 68602
41
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
42
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 79902-63-9 54454
43
Nifedipine Approved Phase 4,Phase 3,Phase 2,Phase 1 21829-25-4 4485
44
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
45
Propantheline Approved Phase 4,Phase 1 298-50-0 4934
46
Tamsulosin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 106133-20-4 129211
47
Exenatide Approved, Investigational Phase 4,Phase 3,Phase 1 141758-74-9 15991534
48
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
49
Insulin Lispro Approved Phase 4,Phase 3 133107-64-9
50
Chlorhexidine Approved, Vet_approved Phase 4,Phase 1 55-56-1 2713 9552079

Interventional clinical trials:

(show top 50) (show all 9562)

# Name Status NCT ID Phase Drugs
1 Folic Acid for Prevention of Contrast Induced Nephropathy Unknown status NCT02444013 Phase 4 Folic acid;Placebo
2 Effects of Antibiotic Prophylaxis on Recurrent UTI in Children Unknown status NCT02357758 Phase 4 Antibiotic Prophylaxis
3 Practical Use of Advagraf de Novo After Kidney Transplantation According to Recipient Genetic Polymorphism Unknown status NCT02311010 Phase 4 Advagraf
4 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
5 Gentamicin Bladder Instillation Trial Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Preventive Effect of Pitavastatin on Contrast-Induced Nephropathy in Patients With Renal Dysfunction Unknown status NCT01871792 Phase 4 Pitavastatin;Placebo
7 The Effects of AST-120 on Endothelial Dysfunction in Patients With Chronic Kidney Disease Unknown status NCT01157260 Phase 4 Kremezin
8 Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients Unknown status NCT00999258 Phase 4 sirolimus
9 Prevention of Contrast-Induced Nephropathy in Diabetic Patients With Undergoing Coronary Angiography Unknown status NCT00950079 Phase 4 Sodium bicarbonate;saline
10 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4 intravenous NAC;Placebo
11 Low Dose Estriol With Lactobacilli Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
12 Safe Renal Function In Long Term Heart Transplanted Patients Unknown status NCT00505102 Phase 4 Everolimus
13 Reduction or Discontinuation of CNI's With Conversion to Everolimus-Based Immunosuppresion Unknown status NCT00443508 Phase 4 adding Certican to therapy;reducing Tacrolimus
14 Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA) Unknown status NCT00290069 Phase 4 Tacrolimus;Rapamycin
15 A Study Comparing Outcomes of Kidney Transplants in Patients on Steroids Versus Those Who Discontinue Steroids Unknown status NCT00273559 Phase 4 prednisone
16 Comparison of Alemtuzumab/Tacrolimus Versus Interleukin-2 Receptor (IL-2R) Monoclonal Antibody (MoAb)/Tacrolimus/Mycophenolate in Kidney Transplantation Unknown status NCT00246129 Phase 4 Alemtuzumab;Daclizumab
17 Pulse Wave Velocity, Pulse Wave Morphology and Blocking of the Reninangiotensin System in Patients With Chronic Kidney Disease Unknown status NCT00235287 Phase 4 Candesartan and enalapril;candesartan and enalapril;candesartan and enalapril;candesartan and enalapril
18 Intravenous Iron in Patients With Anemia of Chronic Kidney Disease Unknown status NCT00204256 Phase 4 Iron sucrose
19 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a Previous Urinary Tract Infection Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
20 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4 Oxycodone
21 Effect of Valsartan vs Perindopril on HOMA-IR Index in Patients With Chronic Kidney Disease Unknown status NCT02299310 Phase 4 Valsartan;Perindopril
22 Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
23 Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection Unknown status NCT01760109 Phase 4 Piperacillin Sodium and Sulbactam Sodium
24 Effect of Vitamin D Supplement on Osteoprotegin Expression and Disease Progression in Patients With Chronic Kidney Disease Stage 1 and 2 Unknown status NCT01561222 Phase 4 Calcitriol;placebo
25 Enhancing Dialysis Adequacy: Effects of Intradialytic Exercise Unknown status NCT01481688 Phase 4
26 Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01426191 Phase 4 xinzhijun
27 Efficacy of Combined Intravesical Therapy With Hyaluronic Acid and Chondroitin Sulphate in the Treatment of Recurrent Cystitis Refractory to Escherichia Coli Extract Unknown status NCT02366676 Phase 4 IALURIL
28 Renal Effects of Meditarranean Diet and Low-protein Diet With Ketoacids on Physiological Intestinal Mibrobiota in CKD Unknown status NCT02302287 Phase 4
29 A Prospective Study Comparing the Success Rate of Injection of (DefluxR) Versus (VantrisR) for VUR in Children Unknown status NCT02271035 Phase 4 Deflux;Vantris
30 The Prevention of Contrast Induced Nephropathy by Sarpogrelate in Patients With Chronic Kidney Disease Unknown status NCT01165567 Phase 4 sarpogrelate
31 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
32 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4 Hydrochlorothiazide and furosemide
33 Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU Unknown status NCT01962116 Phase 4 Citrate 4%;unfractionated heparin
34 Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients Unknown status NCT00889629 Phase 4 Doxercalciferol;placebo
35 Effect of 3g Versus 2 g MMF in Combination With Tacrolimus on Progression of Renal Allograft Interstitial Fibrosis Unknown status NCT01860183 Phase 4 Mycophenolate mofetil
36 Efficacy and Safety of a Covered Self-expandable Dual-layered Metallic Mesh Stent (UVENTA) in Ureteral Obstruction Unknown status NCT01788865 Phase 4
37 Steroid Free Immunosuppression or Calcineurin Inhibitor Minimization After Basiliximab Induction Therapy in Kidney Transplantation: Comparison With a Standard Quadruple Immunosuppressive Regimen Unknown status NCT01560572 Phase 4 tacrolimus OD, mycophenolic acid, prednisolone
38 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
39 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
40 Keto-/Amino Acid Supplemented Low Protein Diet in Patients With Chronic Kidney Disease Unknown status NCT00364884 Phase 4 ketoaminoacid
41 Effects of Spironolactone in Dialysis Unknown status NCT01128101 Phase 4 Spironolactone
42 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
43 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4 N-acetylcysteine
44 The Pharmacogenetics of Optimal Warfarin Therapy in Chinese Patients After Heart Valve Replacement. Unknown status NCT02710747 Phase 4
45 Pure Red Cell Aplasia in Patients With Chronic Kidney Disease and in Use of Epoetin Alfa Unknown status NCT02648126 Phase 4
46 Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients Unknown status NCT02590081 Phase 4 Dextrose 5%;normal saline
47 Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis Unknown status NCT02338635 Phase 4 Ursodeoxycholic Acid
48 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
49 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
50 Anesthetic Technique for AV Fistulae Creation Unknown status NCT01727557 Phase 4

Search NIH Clinical Center for Urinary System Disease

Genetic Tests for Urinary System Disease

Genetic tests related to Urinary System Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Urinary System 28

Anatomical Context for Urinary System Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Urinary System Disease:

18
Kidney

MalaCards organs/tissues related to Urinary System Disease:

38
Kidney, Heart, Bone, Testes, Prostate, Liver, Endothelial

Publications for Urinary System Disease

Articles related to Urinary System Disease:

# Title Authors Year
1
The association of pioglitazone and urinary tract disease in type 2 diabetic taiwanese: bladder cancer and chronic kidney disease. ( 24427312 )
2014
2
Occurrence of bacteriuria in 18 catheterised cats with obstructive lower urinary tract disease: a pilot study. ( 23400682 )
2013
3
Comparison of urine protein profiles in cats without urinary tract disease and cats with idiopathic cystitis, bacterial urinary tract infection, or urolithiasis. ( 21962285 )
2011
4
Bacteriuria in cats with feline lower urinary tract disease: a clinical study of 134 cases in Norway. ( 17693110 )
2007
5
N-Glycans carried by Tamm-Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases. ( 16622944 )
2005
6
Urinary tract diseases revealed after DTP vaccination in infants and young children: cytokine irregularities and down-regulation of cytochrome P-450 enzymes induced by the vaccine may uncover latent diseases in genetically predisposed subjects. ( 15356430 )
2004
7
[Implications of beta 2-microglobulin in the detection of associated urinary tract diseases in patients with infiltrative pulmonary tuberculosis]. ( 12577571 )
2002
8
Expression of platelet-derived endothelial cell growth factor and its potential role in up-regulation of angiogenesis in scarred kidneys secondary to urinary tract diseases. ( 10550316 )
1999
9
Urinary beta-HCG in benign and malignant urinary tract diseases. ( 7542189 )
1995
10
Prevalence of symptomless urinary tract disease in Birmingham schoolchildren. I. Pyuria and bacteriuria. ( 5790270 )
1969

Variations for Urinary System Disease

Expression for Urinary System Disease

Search GEO for disease gene expression data for Urinary System Disease.

Pathways for Urinary System Disease

Pathways related to Urinary System Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.77 FGF23 PTH

GO Terms for Urinary System Disease

Cellular components related to Urinary System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.96 ACE ALB B2M CRP CST3 KLK3
2 extracellular region GO:0005576 9.73 ACE ALB B2M CRP CST3 EPO
3 external side of plasma membrane GO:0009897 9.62 ACE B2M CD79A TRPV1
4 extracellular space GO:0005615 9.36 ACE ALB B2M CRP CST3 EPO
5 slit diaphragm GO:0036057 9.16 NPHS1 NPHS2

Biological processes related to Urinary System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 amyloid-beta metabolic process GO:0050435 9.32 ACE REN
2 response to molecule of bacterial origin GO:0002237 9.26 B2M TLR9
3 angiotensin maturation GO:0002003 9.16 ACE REN
4 excretion GO:0007588 9.13 NPHS1 NPHS2 UMOD
5 cellular protein metabolic process GO:0044267 9.02 ALB B2M CST3 FGF23 KLK3

Molecular functions related to Urinary System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endopeptidase activity GO:0004175 8.8 ACE KLK3 REN

Sources for Urinary System Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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