Aliases & Classifications for Urticaria

MalaCards integrated aliases for Urticaria:

Name: Urticaria 12 72 28 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1555
ICD9CM 34 708.8
ICD10 32 L50

Summaries for Urticaria

Disease Ontology : 12 A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located in the upper dermis.

MalaCards based summary : Urticaria is related to cold urticaria and physical urticaria, and has symptoms including symptoms, darier's sign and gastrointestinal gas. An important gene associated with Urticaria is F12 (Coagulation Factor XII), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and NF-kappaB Signaling. The drugs Clarinex and Cetirizine have been mentioned in the context of this disorder. Affiliated tissues include the upper dermis, skin and testes, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. They may also burn... more...

Related Diseases for Urticaria

Diseases related to Urticaria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 287)
# Related Disease Score Top Affiliating Genes
1 cold urticaria 33.9 CMA1 NLRP3 PLCG2 RNASE3
2 physical urticaria 33.8 ADGRE2 FCER1A MS4A2
3 dermatographia 33.1 FCER1A MS4A2
4 angioedema 30.3 C1S CPN1 F12 HNMT LTC4S PTGS1
5 allergic rhinitis 29.8 HRH1 MS4A2 RNASE3
6 hydrops, lactic acidosis, and sideroblastic anemia 29.5 C1S PTGS1 PTGS2
7 conjunctivitis 29.3 HRH1 MS4A2 NLRP3 RNASE3
8 allergic hypersensitivity disease 29.3 FCER2 HRH1 MS4A2 RNASE3 TPT1
9 ige responsiveness, atopic 29.2 FCER2 MS4A2 RNASE3
10 dermatitis, atopic 28.6 CMA1 FCER2 HRH1 MS4A2 RNASE3 SELE
11 asthma 27.4 FCER1A FCER2 HNMT HRH1 LTC4S MS4A2
12 vibratory urticaria 12.5
13 cholinergic urticaria 12.4
14 solar urticaria 12.4
15 urticaria, aquagenic 12.3
16 urticaria pigmentosa 12.3
17 allergic urticaria 12.1
18 papular urticaria 12.0
19 familial cold autoinflammatory syndrome 3 12.0
20 schnitzler syndrome 12.0
21 muckle-wells syndrome 12.0
22 nodular urticaria pigmentosa 11.9
23 familial cold autoinflammatory syndrome 1 11.8
24 urticaria, familial localized heat 11.8
25 plaque-form urticaria pigmentosa 11.8
26 typical urticaria pigmentosa 11.8
27 maculopapular cutaneous mastocytosis 11.5
28 familial cold autoinflammatory syndrome 11.4
29 mast cell disease 11.3
30 familial cold autoinflammatory syndrome 4 11.2
31 exercise-induced anaphylaxis 11.1
32 cutaneous mastocytosis 11.1
33 cryopyrin-associated periodic syndrome 11.1
34 wheat allergy 11.1
35 peanut allergy 11.1
36 dermographism, familial 10.9
37 fascioliasis 10.9
38 arthus reaction 10.8
39 carboxypeptidase n deficiency 10.8
40 netherton syndrome 10.8
41 deafness, autosomal dominant 34, with or without inflammation 10.8
42 paragonimiasis 10.8
43 cystic echinococcosis 10.8
44 hypersensitivity vasculitis 10.8
45 anca-associated vasculitis 10.8
46 episodic angioedema with eosinophilia 10.8
47 hypocomplementemic urticarial vasculitis 10.8
48 monoclonal mast cell activation syndrome 10.8
49 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.3
50 blepharoconjunctivitis 10.3 CMA1 RNASE3

Comorbidity relations with Urticaria via Phenotypic Disease Network (PDN):


Acute Cystitis Hypertension, Essential
Ischemic Heart Disease

Graphical network of the top 20 diseases related to Urticaria:



Diseases related to Urticaria

Symptoms & Phenotypes for Urticaria

UMLS symptoms related to Urticaria:


symptoms, darier's sign, gastrointestinal gas, vertigo/dizziness, welts, chronic pain, syncope, sciatica, pruritus, pelvic pain, pain, nausea and vomiting, icterus, heartburn, headache, halitosis, fever, fatigue, exanthema, edema, dyspepsia, diarrhea, coughing, constipation, chest pain, abdominal pain

MGI Mouse Phenotypes related to Urticaria:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 AOC1 CMA1 FCER1A FCER2 HRH1 MS4A2
2 immune system MP:0005387 9.4 CMA1 CPN1 FCER1A FCER2 HRH1 LTC4S

Drugs & Therapeutics for Urticaria

FDA approved drugs:

# Drug Name Active Ingredient(s) 17 Company Approval Date
1
Clarinex 17 DESLORATADINE Schering-Plough February 2002

Drugs for Urticaria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 289)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678
2
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2 100643-71-8 124087
3
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-45-6, 75614-87-8 774
4
Levocetirizine Approved Phase 4,Phase 3,Phase 1,Phase 2 130018-77-8
5
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 242138-07-4
6 Ebastine Approved, Investigational Phase 4 90729-43-4 3191
7
Fexofenadine Approved, Investigational Phase 4,Phase 2 83799-24-0 3348
8
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2 79794-75-5 3957
9
Hydroxyzine Approved Phase 4 68-88-2 3658
10
Cefazolin Approved Phase 4 25953-19-9 33255 656510
11
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
12
Clevidipine Approved, Investigational Phase 4 167221-71-8
13
Praziquantel Approved, Investigational, Vet_approved Phase 4 55268-74-1 4891
14
Azelastine Approved Phase 4,Phase 3 58581-89-8 2267
15
Icatibant Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 130308-48-4, 138614-30-9 71364
16
Dapsone Approved, Investigational Phase 4 80-08-0 2955
17
Menthol Approved Phase 4 2216-51-5 16666
18
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3 50-14-6 5280793
19
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 1406-16-2
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
21
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 143 6006
22
Bradykinin Investigational Phase 4,Phase 3,Phase 2,Phase 1 58-82-2 439201
23
Lactitol Investigational Phase 4,Phase 2 585-86-4 3871
24 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
25 Cholinergic Agents Phase 4,Phase 3,Phase 2
26 Cholinergic Antagonists Phase 4,Phase 3,Phase 2
27 Histamine Antagonists Phase 4,Phase 3,Phase 2,Phase 1
28 Histamine H1 Antagonists Phase 4,Phase 3,Phase 2,Phase 1
29 Histamine H1 Antagonists, Non-Sedating Phase 4,Phase 3,Phase 2
30
Histamine Phosphate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-74-1 65513
31 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
33 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Antipruritics Phase 4,Phase 3,Phase 2
35 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Vaccines Phase 4,Phase 2
37 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
38 Bronchodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
40 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
41 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
42 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
43 Kininogens Phase 4,Phase 3,Phase 2,Phase 1
44 Vasodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Immunoglobulin E Phase 4
46 Antibodies, Monoclonal Phase 4,Phase 3,Phase 2,Phase 1
47 Angiotensin-Converting Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
48 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
49
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
50 Anti-Bacterial Agents Phase 4,Phase 1

Interventional clinical trials:

(show top 50) (show all 325)

# Name Status NCT ID Phase Drugs
1 The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria Unknown status NCT00346606 Phase 4 Denosin® and Xyzal®
2 Omalizumab in Chronic Spontaneous Urticaria Patients Non Responding to Initial Standard antihistaminE Treatment Completed NCT02550106 Phase 4 OMALIZUMAB
3 Evaluation of the Inhibitory Effect of 5 Anti-Histamines in Urticaria Completed NCT01940393 Phase 4 Cetirizine;Desloratadine;Fexofenadine;Ebastine;Bilastine
4 Desloratadine 5, 10 and 20mg in Patients With Cold Urticaria Completed NCT01444196 Phase 4 Desloratadine
5 Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Levocetirizine Alone in High Doses Completed NCT01250652 Phase 4 Levocetirizine;Levocetirizine plus Hydroxyzine
6 A Study of the Efficacy and Safety of Omalizumab Through 48 Weeks in Participants With Chronic Idiopathic Urticaria Completed NCT02392624 Phase 4 Omalizumab;Placebo
7 A Study to Assess and Compare the Effects of 5 mg vs. 20 mg Desloratadine on the Development of Cold Urticaria Lesions Completed NCT00600847 Phase 4 desloratadine;desloratadine;placebo
8 Study for the Treatment of Chronic Idiopathic Urticaria With High Doses of AERIUS (Desloratadine) (Study P04849) Completed NCT00536380 Phase 4 5-mg Desloratadine;10-mg Desloratadine;20-mg Desloratadine
9 CUTE (Chronic Urticaria Treatment Evaluation) Completed NCT00264303 Phase 4 Levocetirizine;Desloratadine
10 A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147) Completed NCT00783354 Phase 4 desloratadine;desloratadine
11 An Open-Label Study of the Effects of Desloratadine (Aerius.) Treatment on the Quality of Life of Patients With Chronic Idiopathic Urticaria (Study P02540) Completed NCT00795522 Phase 4 Desloratadine
12 A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735) Completed NCT00751218 Phase 4 desloratadine;placebo;cetirizine
13 Effects of Bilastine on F1 Simulator Driving Performance in Patients Affected by Allergic Rhinitis and/or Urticaria Completed NCT02576041 Phase 4 Bilastine;Placebo
14 A Post Marking Study to Evaluate the Safety of FluMist in Children Completed NCT00569894 Phase 4
15 Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction Completed NCT01244698 Phase 4 Cefadroxil discontinued early;Cefadroxil until drain removal
16 Clevidipine for Vasoreactivity Evaluation of the Pulmonary Arterial Bed Completed NCT01121458 Phase 4 Clevidipine
17 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix TM) Administered in Healthy Adolescents Completed NCT00534638 Phase 4
18 Evaluation of Praziquantel Dosage for Treatment of Schistosomiasis in Brazil Completed NCT00403611 Phase 4 Praziquantel 60 mg/kg;Praziquantel 40 mg/kg
19 Safety of Astepro 0.15% Nasal Spray and Astepro 0.1% Nasal Spray in Children Ages >6 Months to <6 Years With AR Completed NCT01880840 Phase 4 205.5 mcg of azelastine hydrochloride;137 mcg of azelastine hydrochloride
20 A Call Center During HAE Attacks (SOS HAE) Completed NCT01679912 Phase 4
21 Postmarketing Immunogenicity Study in HAE Subjects Treated With Berinert Completed NCT01467947 Phase 4
22 Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE Completed NCT01457430 Phase 4 Icatibant
23 A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE Completed NCT00914966 Phase 4
24 Sustained Effect of Urticaria Remission With Relatively High Dose Vitamin D Supplementation After Omalizumab Discontinuation Recruiting NCT02742805 Phase 4 Omalizumab
25 Role of Immunoglobulin E (IgE) Bearing Cells in Chronic Idiopathic Urticaria (CIU) Recruiting NCT03111628 Phase 4 Omalizumab
26 Treatment of Chronic Urticarial Unresponsive to H1-antihistamines With an Anti-IL5Ralpha Monoclonal Antibody Recruiting NCT03183024 Phase 4
27 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4 Dapsone
28 Treatment of Idiopathic Angioedema With Xolair as Add-on Therapy Recruiting NCT02966314 Phase 4 Omalizumab;Placebos
29 Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria Active, not recruiting NCT01701583 Phase 4 Omalizumab
30 Menthol for PDT Pain Not yet recruiting NCT02984072 Phase 4 Menthol;Aqueous Cream
31 A Comparative Double-blind, Double-dummy Study of Desloratadine (DL) 5 mg Once Daily, Cetirizine 10 mg Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03736) Terminated NCT00751166 Phase 4 Desloratadine;Cetirizine;placebo
32 Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema Terminated NCT01574248 Phase 4 icatibant
33 C1-INH Compared to Placebo at the Time of Prodromal Symptoms for Hereditary Angioedema (HAE) Exacerbation Withdrawn NCT01151735 Phase 4 C-1-esterase;C-1-esterase;placebo
34 Efficacy and Safety of Omalizumab in Chronic Idiopathic Urticaria Unknown status NCT02166151 Phase 3 Omalizimab
35 Efficacy of Levocetirizine Fourfold Dosage in Chronic Spontaneous Urticaria Unknown status NCT02372604 Phase 3 Levocetirizine (as levocetirizine dihydrochloride), 5mg ( then 20 mg) per day . Oral administration.;Levocetirizine, (as levocetirizine dihydrochloride) 20 mg ( then 5 mg) per day. Oral administration.
36 Bilastine Updosing in Chronic Spontaneous Urticaria Completed NCT02213367 Phase 3 Bilastine;Bilastine;Bilastin
37 Glucocorticoids With Antihistamines Versus Antihistamines in Acute Urticaria in Emergency Completed NCT02565680 Phase 2, Phase 3 placebo;prednisone
38 Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU) Completed NCT00598611 Phase 3 desloratadine;desloratadine
39 Methotrexate in the Treatment of Chronic Idiopathic Urticaria Completed NCT01960283 Phase 3 Methotrexate (Novatrex ®) + anti-H1;Placebo + anti-H1
40 Study of the Effects of Chinese Herbal Medicine on Chronic Urticaria Completed NCT01715740 Phase 3 Chinese Herbal Medicine (CHM);Placebo
41 OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients Completed NCT02161562 Phase 3 omalizumab;omalizumab
42 An Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Chronic Urticaria (MK-4117-201) Completed NCT01916967 Phase 3 Desloratadine;Placebo
43 Prospective Double-blind Placebo-controlled Study of the Effect of Xolair (Omalizumab) in Chronic Urticaria Patients Completed NCT01803763 Phase 2, Phase 3 Omalizumab (Xolair);Placebo
44 Efficacy Study for the Symptomatic Treatment of Chronic Idiopathic Urticaria Completed NCT00421109 Phase 3 Bilastine;Levocetirizine;Placebo
45 How Desloratadine (Clarinex, Aerius) Affects Quality of Life in Patients With Chronic Idiopathic Urticaria (Have Had Hives for 6 Weeks or Longer)(Study P02988) Completed NCT00795158 Phase 3 desloratadine
46 A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor Antagonists Completed NCT01264939 Phase 3 Omalizumab;Placebo;H1 antihistamine, H2 antihistamine, leukotriene receptor antagonist;Diphenhydramine
47 Study to Compare the Efficacy and Safety Between Levocetirizine and Loratadine for Chronic Idiopathic Urticaria Completed NCT00525382 Phase 3 levocetirizine dihydrochloride
48 Bilastine Updosing - Characterization of Underlying Mechanisms Completed NCT01271075 Phase 2, Phase 3 Bilastine;Bilastine
49 Multicenter Pilot Phase III Clinical Trials of JDP-205 iv Injection for the Treatment of Acute Urticaria Associated With an Acute Allergic Reaction. Completed NCT02023164 Phase 3 JDP-205 Injection;Diphenhydramine
50 A Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine (H1) Treatment Completed NCT01287117 Phase 3 Omalizumab;Placebo

Search NIH Clinical Center for Urticaria

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Urticaria

Genetic tests related to Urticaria:

# Genetic test Affiliating Genes
1 Urticaria 28

Anatomical Context for Urticaria

The Foundational Model of Anatomy Ontology organs/tissues related to Urticaria:

18
The Upper Dermis

MalaCards organs/tissues related to Urticaria:

38
Skin, Testes, Thyroid, Bone, Brain, T Cells, Neutrophil

Publications for Urticaria

Articles related to Urticaria:

(show top 50) (show all 1744)
# Title Authors Year
1
Chronic inducible urticaria: a systematic review of treatment options. ( 29438771 )
2018
2
A case of contact dermatitis and contact urticaria syndrome due to multiple allergens observed in a professional baseball player. ( 29395964 )
2018
3
Treatment Patterns, Healthcare Resource Utilization, and Spending Among Medicaid-Enrolled Children with Chronic Idiopathic/Spontaneous Urticaria in the United States. ( 29429043 )
2018
4
Successful treatment of refractory cholinergic urticaria with omalizumab. ( 29057464 )
2018
5
Paediatric solar urticaria: A case series. ( 29315482 )
2018
6
Chronic spontaneous urticaria in children - a systematic review on interventions and comorbidities. ( 29392757 )
2018
7
Development and Validation of the Cholinergic Urticaria Quality of Life Questionnaire: CholU-QoL. ( 29369455 )
2018
8
The role and relevance of mast cells in urticaria. ( 29431202 )
2018
9
Effectiveness of omalizumab in adolescent and adult patients with chronic idiopathic/spontaneous urticaria: a systematic review of 'real-world' evidence. ( 29431518 )
2018
10
Two-week intervals during omalizumab treatment may provide better symptom control in selected patients with chronic urticaria. ( 29410306 )
2018
11
Posttraumatic stress disorder, emotional suppression and psychiatric co-morbidity in patients with chronic idiopathic urticaria: a moderated mediation analysis. ( 29431522 )
2018
12
Serum Sickness-like Reaction in a Pediatric Patient using Omalizumab for Chronic Spontaneous Urticaria. ( 29444344 )
2018
13
Treatment response to omalizumab in patients with refractory chronic spontaneous urticaria. ( 29399789 )
2018
14
Occupational allergic rhinitis and contact urticaria caused by Gum Arabic in a candy factory worker. ( 29446105 )
2018
15
The treatment outcomes and dose de-escalation of desloratadine up-dosing in chronic spontaneous urticaria. ( 29380864 )
2018
16
Urticaria multiforme, an "erythema multiforme" simulator. ( 29398004 )
2018
17
The functional and structural alterations of the striatum in chronic spontaneous urticaria. ( 29379058 )
2018
18
Use of skin biomarker profiles to distinguish Schnitzler syndrome from chronic spontaneous urticaria: results of a pilot study. ( 28580686 )
2018
19
Global Burden of Urticaria: Insights from the 2016 Global Burden of Disease Study. ( 29438758 )
2018
20
Cholinergic urticaria: epidemiology, physiopathology, new categorization, and management. ( 28382552 )
2017
21
Cyclosporine for Chronic Spontaneous Urticaria: A Meta-Analysis and Systematic Review. ( 28916431 )
2017
22
Yellow urticaria following plasma transfusion. ( 28894877 )
2017
23
Clinical and photobiological response in eight patients with solar urticaria under treatment with omalizumab, and review of the literature. ( 29171925 )
2017
24
Recurrence of Chronic Urticaria: Incidence and Associated Factors. ( 28888844 )
2017
25
Omalizumab is effective in cold urticaria-results of a randomized placebo-controlled trial. ( 28389393 )
2017
26
Angioedema, Stomatitis, and Urticaria Caused by Contact Allergy to Invisalign. ( 28885312 )
2017
27
Patient Perspectives: What is papular urticaria? ( 29144044 )
2017
28
Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations. ( 28913986 )
2017
29
Cryptogenic cirrhosis: misunderstood cause of yellow urticaria. ( 28609562 )
2017
30
Schnitzler syndrome: A rare cause of chronic recalcitrant urticaria successfully treated with Anakinra. ( 29027204 )
2017
31
Prevalence of papular urticaria caused by flea bites and associated factors in children 1-6A years of age in BogotA!, D.C. ( 29158868 )
2017
32
Urticaria pigmentosa with concomitant polycythaemia vera in a 3-year-old boy. ( 28614617 )
2017
33
Beyond Urticaria: Schnitzler Syndrome. ( 28552842 )
2017
34
Solar urticaria with an augmentation spectrum in a child. ( 28543282 )
2017
35
Response to Omalizumab in Solar Urticaria: Report of 3 Cases. ( 28457471 )
2017
36
Cholinergic urticaria patients of different age groups have distinct features. ( 28873238 )
2017
37
Localized salt-dependent aquagenic urticaria, a rare subtype of urticaria: a case report. ( 29384119 )
2017
38
Looking forward to new targeted treatments for chronic spontaneous urticaria. ( 28078079 )
2017
39
Perioperative Management of a Patient with Cold Urticaria. ( 29326933 )
2017
40
Benefit from Reslizumab Treatment in a Patient with Chronic Spontaneous Urticaria and Cold Urticaria. ( 28924988 )
2017
41
The link between chronic spontaneous urticaria and metabolic syndrome. ( 28884987 )
2017
42
Clinical characteristics in cholinergic urticaria with palpebral angioedema: Report of 15 cases. ( 27876252 )
2017
43
Solar urticaria developing in patients with Erythropoietic Protoporphyria: a clue to the pathogenesis of Solar Urticaria? ( 28796891 )
2017
44
Seroprevalence of Toxocariasis In Children With Urticaria: A Population-Based Study. ( 28077610 )
2017
45
When should the diagnosis 'contact urticaria' be used? ( 28940487 )
2017
46
Increased serum soluble vascular endothelial cadherin levels in patients with chronic spontaneous urticaria. ( 28583263 )
2017
47
Solar urticaria with a wide action spectrum from UVB to visible light complicated with UVA-induced polymorphous light eruption. ( 28160768 )
2017
48
Physical urticaria. ( 28433981 )
2017
49
Immunological Mechanisms Implicated in the Pathogenesis of Chronic Urticaria and Hashimoto Thyroiditis. ( 28865416 )
2017
50
Burden of chronic urticaria relative to psoriasis in five European countries. ( 28898460 )
2017

Variations for Urticaria

ClinVar genetic disease variations for Urticaria:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 F12 NM_000505.3(F12): c.983C> G (p.Thr328Arg) single nucleotide variant Pathogenic rs118204456 GRCh37 Chromosome 5, 176831232: 176831232

Expression for Urticaria

Search GEO for disease gene expression data for Urticaria.

Pathways for Urticaria

GO Terms for Urticaria

Cellular components related to Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.28 AOC1 C1S F12 FCER2 HNMT PLCG2

Biological processes related to Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of receptor internalization GO:0002092 9.46 PLCG2 SELE
2 prostaglandin metabolic process GO:0006693 9.43 PTGS1 PTGS2
3 cellular oxidant detoxification GO:0098869 9.43 LTC4S PTGS1 PTGS2
4 lipoxygenase pathway GO:0019372 9.4 LTC4S PTGS2
5 prostaglandin biosynthetic process GO:0001516 9.37 PTGS1 PTGS2
6 cyclooxygenase pathway GO:0019371 9.32 PTGS1 PTGS2
7 regulation of inflammatory response GO:0050727 9.26 CMA1 NLRP3 PTGS2 SELE
8 inflammatory response GO:0006954 9.17 ADGRE2 HRH1 MS4A2 NLRP3 PTGS1 PTGS2
9 cellular response to histamine GO:0071420 9.16 AOC1 HRH1

Molecular functions related to Urticaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.65 ADGRE2 AOC1 C1S F12 TPT1
2 peroxidase activity GO:0004601 9.16 PTGS1 PTGS2
3 prostaglandin-endoperoxide synthase activity GO:0004666 8.96 PTGS1 PTGS2
4 IgE binding GO:0019863 8.8 FCER1A FCER2 MS4A2

Sources for Urticaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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