Aliases & Classifications for Urticaria Pigmentosa

Aliases & Descriptions for Urticaria Pigmentosa:

Name: Urticaria Pigmentosa 12 52 42 14 69
Up/mpcm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12309
ICD10 33 Q82.2
MeSH 42 D014582
NCIt 47 C3433
UMLS 69 C0042111

Summaries for Urticaria Pigmentosa

MalaCards based summary : Urticaria Pigmentosa, also known as up/mpcm, is related to keloids and nodular urticaria pigmentosa, and has symptoms including macule An important gene associated with Urticaria Pigmentosa is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways/superpathways are Signaling by GPCR and PI3K-Akt signaling pathway. Affiliated tissues include skin, bone and bone marrow.

Wikipedia : 71 Urticaria pigmentosa (also known as \"Generalized eruption of cutaneous mastocytosis (childhood type)\"... more...

Related Diseases for Urticaria Pigmentosa

Diseases related to Urticaria Pigmentosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
id Related Disease Score Top Affiliating Genes
1 keloids 29.6 CALCA VIP
2 nodular urticaria pigmentosa 12.0
3 plaque-form urticaria pigmentosa 11.9
4 typical urticaria pigmentosa 11.9
5 maculopapular cutaneous mastocytosis 11.6
6 mast cell disease 11.4
7 cutaneous mastocytosis 11.3
8 urticaria 11.0
9 monoclonal mast cell activation syndrome 10.9
10 mastocytosis 10.5
11 systemic mastocytosis 10.2
12 intracranial sinus thrombosis 10.2 KIT KITLG
13 uremic neuropathy 10.2 KIT KITLG
14 hemangioma of peripheral nerve 10.2 KIT KITLG
15 high grade b-cell lymphoma with rearrangements of myc and bcl2 and/or bcl6 10.2 KIT KITLG
16 priapism 10.2 KIT KITLG
17 extranodal nasal nk/t cell lymphoma 10.2 KIT KITLG
18 epidermolysis bullosa simplex, recessive 1 10.2 KIT KITLG
19 syndromic x-linked intellectual disability 10.2 KIT KITLG
20 dentinogenesis imperfecta, shields type ii 10.1 KIT KITLG
21 cowden syndrome 3 10.1 CALCA KIT
22 oculogyric crisis 10.1 TAC1 VIP
23 drug psychosis 10.1 TAC1 VIP
24 subendocardial myocardial infarction 10.1 CALCA KIT
25 diabetic macular edema 10.1 KIT VIP
26 wells-jankovic syndrome 10.1 CALCA VIP
27 cartilage disease 10.1 CALCA TAC1
28 telangiectasia macularis eruptiva perstans 10.1
29 leukemia 10.1
30 volkmann contracture 10.1 CALCA VIP
31 temporomandibular ankylosis 10.1 KIT KITLG
32 cockayne syndrome type i 10.1 CALCA VIP
33 spinal stenosis 10.1 CALCA VIP
34 gemistocytic astrocytoma 10.1 CALCA VIP
35 olfactory nerve disease 10.0 CMA1 KIT KITLG
36 kidney rhabdoid cancer 10.0 CMA1 KIT KITLG
37 pericoronitis 10.0 CMA1 KIT KITLG
38 hemopericardium 10.0 CALCA TAC1
39 prostate cancer, hereditary, x-linked 1 10.0 KIT KITLG
40 central nervous system lymphoma 10.0 CALCA TAC1
41 salpingo-oophoritis 10.0 CALCA TAC1
42 central nervous system origin vertigo 10.0 CMA1 IL2RA
43 infantile hypotonia 10.0 CALCA TAC1
44 sweat gland cancer 10.0 KIT TAC1 VIP
45 brown-vialetto-van laere syndrome 10.0 CALCA KIT
46 partial of retinal vein occlusion 10.0 IL2RA KITLG
47 tooth agenesis, selective, 5 10.0 KIT TAC1 VIP
48 corneal ulcer 10.0 CALCA TAC1
49 juvenile xanthogranuloma 10.0
50 osteoporosis 10.0

Graphical network of the top 20 diseases related to Urticaria Pigmentosa:



Diseases related to Urticaria Pigmentosa

Symptoms & Phenotypes for Urticaria Pigmentosa

UMLS symptoms related to Urticaria Pigmentosa:


macule

Drugs & Therapeutics for Urticaria Pigmentosa

Interventional clinical trials:


id Name Status NCT ID Phase
1 Ultraviolet (UVA and UVB) Light Therapy in the Treatment of Inflammatory Skin Conditions Terminated NCT00129415 Phase 1, Phase 2
2 Natural History of Urticaria Pigmentosa in Children Completed NCT00467792
3 Cytokine Production Patterns in Patients With Systemic Mastocytosis Compared With Atopic Dermatitis and Healthy Individuals Completed NCT00001760
4 Cause and Natural Course of Pediatric-Onset Mastocytosis Completed NCT00050193
5 Cutaneous Mastocytosis in Children: Analysis of Somatic and Germline Mutations Recruiting NCT02761473
6 Study of Factors Regulating Mast Cell Proliferation Recruiting NCT00044122
7 Mast Cell Connect: A Registry for Patients With Mastocytosis Recruiting NCT02620254

Search NIH Clinical Center for Urticaria Pigmentosa

Cochrane evidence based reviews: urticaria pigmentosa

Genetic Tests for Urticaria Pigmentosa

Anatomical Context for Urticaria Pigmentosa

MalaCards organs/tissues related to Urticaria Pigmentosa:

39
Skin, Bone, Bone Marrow, Testes, Smooth Muscle, Monocytes, Thyroid

Publications for Urticaria Pigmentosa

Articles related to Urticaria Pigmentosa:

(show top 50) (show all 370)
id Title Authors Year
1
General Anesthesia in a Patient With Urticaria Pigmentosa Referred for Electroconvulsive Therapy. ( 26934274 )
2016
2
Urticaria pigmentosa. ( 26752589 )
2015
3
Urticaria pigmentosa-like disease in a dog. ( 25750443 )
2015
4
Urticaria pigmentosa masquerading as non-accidental injury. ( 25784750 )
2015
5
NKp46 regulates the production of serine proteases and IL-22 in human mast cells in urticaria pigmentosa. ( 25940096 )
2015
6
Sustained improvement in urticaria pigmentosa and pruritus in a case of indolent systemic mastocytosis treated with cladribine. ( 25515765 )
2015
7
A segmental rash in a young male: a quiz. Naevoid urticaria pigmentosa. ( 23828224 )
2014
8
Urticaria pigmentosa complicated with esophageal eosinophilia. ( 25437994 )
2014
9
A 1-year-old boy with persistent, generalized eruption. Urticaria pigmentosa. ( 24549082 )
2014
10
Telangiectasia macularis eruptiva perstans or highly vascularized urticaria pigmentosa? ( 25439382 )
2014
11
Cutaneous mastocytosis: a case of bullous urticaria pigmentosa. ( 23513553 )
2013
12
Response of urticaria pigmentosa to cladribine in a patient with systemic mastocytosis. ( 23205635 )
2013
13
Dermatoscopic findings of urticaria pigmentosa. ( 24474113 )
2013
14
Acute interstitial nephritis secondary to long-term use of cetirizine for the treatment of urticaria pigmentosa. ( 23083330 )
2013
15
Familial urticaria pigmentosa: report of a family and review of the role of KIT mutations. ( 22892471 )
2013
16
Urticaria pigmentosa in a female patient with celiac disease: response to a gluten-free diet. ( 22465751 )
2013
17
Dermatophytosis and papular eosinophilic/mastocytic dermatitis (urticaria pigmentosa-like dermatitis) in three Devon Rex cats. ( 22736683 )
2012
18
Nevoid urticaria pigmentosa along Blaschko's line. ( 22221017 )
2012
19
Urticaria pigmentosa after treatment with TNF antagonists: a case report. ( 22184778 )
2011
20
Gastroesophageal reflux disease accompanying urticaria pigmentosa. ( 22185927 )
2011
21
Cutaneous mastocytosis in twins: multiple mastocytomas and urticaria pigmentosa in two pairs of monozygotic twins. ( 21385209 )
2011
22
Generalized brownish macules in infancy. Urticaria pigmentosa. ( 19873965 )
2009
23
Megalocornea-urticaria pigmentosa syndrome--a new syndrome? ( 19706342 )
2009
24
Urticaria pigmentosa associated with acute stress and lesional skin mast-cell expression of CRF-R1. ( 19094125 )
2009
25
CD25 expression on cutaneous mast cells from adult patients presenting with urticaria pigmentosa is predictive of systemic mastocytosis. ( 18162781 )
2008
26
Mastocytosis with urticaria pigmentosa and osteoporosis. ( 19061601 )
2008
27
Urticaria pigmentosa. A case report. ( 18709295 )
2008
28
What is your diagnosis? Cutaneous mastocytosis (urticaria pigmentosa). ( 18543588 )
2008
29
Picture of the month. Urticaria pigmentosa. ( 18391148 )
2008
30
Unusual cutaneous findings of urticaria pigmentosa and telangiectasia macularis eruptiva perstans associated with marked myelofibrosis. ( 17040445 )
2006
31
Urticaria pigmentosa and mastocytosis: the role of immunophenotyping in diagnosis and determining response to treatment. ( 16822380 )
2006
32
Anesthetic management of a labouring parturient with urticaria pigmentosa. ( 16575037 )
2006
33
The cosmetic treatment of urticaria pigmentosa with Nd:YAG laser at 532 nanometers. ( 17166203 )
2005
34
Intertriginous urticaria pigmentosa. ( 15604555 )
2005
35
Nodular scabies mimicking urticaria pigmentosa in an infant. ( 16045712 )
2005
36
Localized urticaria pigmentosa triggered by mesotherapy. ( 15539904 )
2004
37
Papular eosinophilic/mastocytic dermatitis (feline urticaria pigmentosa) in Devon Rex cats: A distinct disease entity or a histopathological reaction pattern? ( 15305933 )
2004
38
Urticaria pigmentosa. ( 15120152 )
2004
39
Evolution of urticaria pigmentosa into indolent systemic mastocytosis: abnormal immunophenotype of mast cells without evidence of c-kit mutation ASP-816-VAL. ( 12688351 )
2003
40
Severe pruritus in a patient with urticaria pigmentosa treated with topical 5% urea and 3% polidocanol cream. ( 14522633 )
2003
41
Association of urticaria pigmentosa with cafAc-au-lait spots, neurofibromas and neurofibroma-like neoplasms: a mere coincidence? ( 12771469 )
2003
42
Familial urticaria pigmentosa associated with thrombocytosis as the initial symptom of systemic mastocytosis and Down's syndrome. ( 14761147 )
2003
43
Urticaria pigmentosa localized on radiation field. ( 12948928 )
2003
44
Medium- versus high-dose ultraviolet A1 therapy for urticaria pigmentosa: a pilot study. ( 14512916 )
2003
45
Anaphylaxis to insect sting associated with urticaria pigmentosa. ( 12866320 )
2003
46
Scabies incognito presenting as urticaria pigmentosa in an infant. ( 12383096 )
2002
47
Regression of urticaria pigmentosa in adult patients with systemic mastocytosis: correlation with clinical patterns of disease. ( 12056960 )
2002
48
Mast cells with bilobed or multilobed nuclei in a nodular lesion of a patient with urticaria pigmentosa. ( 12454601 )
2002
49
Infantile fibrosarcoma associated with urticaria pigmentosa. ( 12186369 )
2002
50
An infant with urticaria pigmentosa and rickets. ( 12027094 )
2002

Variations for Urticaria Pigmentosa

Expression for Urticaria Pigmentosa

Search GEO for disease gene expression data for Urticaria Pigmentosa.

Pathways for Urticaria Pigmentosa

GO Terms for Urticaria Pigmentosa

Cellular components related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 CALCA CMA1 KITLG TAC1 VIP

Biological processes related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

(show all 11)
id Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.58 IL2RA KIT KITLG
2 regulation of phosphatidylinositol 3-kinase signaling GO:0014066 9.49 KIT KITLG
3 regulation of blood pressure GO:0008217 9.48 CALCA TAC1
4 positive regulation of MAP kinase activity GO:0043406 9.46 KIT KITLG
5 ovarian follicle development GO:0001541 9.43 KIT KITLG
6 cellular response to nerve growth factor stimulus GO:1990090 9.37 CALCA TAC1
7 response to pain GO:0048265 9.32 CALCA TAC1
8 positive regulation of ossification GO:0045778 9.26 CALCA TAC1
9 inflammatory response GO:0006954 9.26 CALCA IL2RA KIT TAC1
10 embryonic hemopoiesis GO:0035162 9.16 KIT KITLG
11 ectopic germ cell programmed cell death GO:0035234 8.62 KIT KITLG

Molecular functions related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 8.96 KIT KITLG
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.8 IL2RA KIT KITLG

Sources for Urticaria Pigmentosa

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