Aliases & Classifications for Urticaria Pigmentosa

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH, 38NCIt
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Urticaria Pigmentosa, Aliases & Descriptions:

Name: Urticaria Pigmentosa 9 43 60
 
Up/mpcm 9


External Ids:

Disease Ontology9 DOID:12309
MeSH33 D014582
SNOMED-CT55 205566001, 78745000
NCIt38 C3433

Summaries for Urticaria Pigmentosa

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Wikipedia:63 Urticaria pigmentosa (also known as \"Generalized eruption of cutaneous mastocytosis (childhood type)\"... more...

MalaCards based summary: Urticaria Pigmentosa, also known as up/mpcm, is related to systemic mastocytosis and mastocytosis. An important gene associated with Urticaria Pigmentosa is KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog), and among its related pathways are Endocytosis and Melanocyte Development and Pigmentation. The compounds 2-chlorodeoxyadenosine and chloroquine have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and bone marrow, and related mouse phenotypes are digestive/alimentary and hematopoietic system.

Related Diseases for Urticaria Pigmentosa

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Diseases related to Urticaria Pigmentosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1systemic mastocytosis31.1KITLG, KIT
2mastocytosis30.7KIT, IL2RA, CMA1, KITLG
3leukemia30.4IL2RA, KITLG, KIT
4neurofibroma30.3KITLG, KIT
5polycythemia vera30.3KIT, KITLG
6gastrointestinal stromal tumor30.3KITLG, KIT
7asthma30.0CMA1, IL2RA, KITLG
8psoriasis30.0CMA1, IL2RA
9mast cell neoplasm29.8CMA1, KIT, KITLG
10urticaria11.4
11cutaneous mastocytosis10.6
12mast cell disease10.4
13nodular urticaria pigmentosa10.4
14osteoporosis10.3
15juvenile xanthogranuloma10.3
16plaque-form urticaria pigmentosa10.3
17typical urticaria pigmentosa10.3
18gastroesophageal reflux10.2
19syringoma10.2
20indolent systemic mastocytosis10.2
21dermatitis10.2
22eosinophilia10.2
23lymphoblastic leukemia10.2
24scabies10.2
25hypereosinophilic syndrome10.2IL2RA, KIT
26piebaldism10.1KIT, KITLG
27dysgerminoma10.1KIT, KITLG
28refractory anemia10.1KIT, KITLG
29chronic myelomonocytic leukemia10.1KIT, KITLG
30severe combined immunodeficiency, x-linked10.1KITLG, IL2RA
31essential thrombocythemia10.1KITLG, KIT
32precursor b-cell acute lymphoblastic leukemia10.1KITLG, KIT
33neurofibromatosis10.1KITLG, KIT
34celiac disease10.1
35wilms tumor10.1
36atopy10.1
37multiple myeloma10.1
38keloids10.1
39myelofibrosis10.1
40skin disease10.1
41thrombocytosis10.1
42acromegaly10.1
43mast-cell leukemia10.1
44lichen planus10.1
45rickets10.1
46acanthosis nigricans10.1
47parapsoriasis10.1
48otosclerosis10.1
49amyloidosis10.1
50dermatophytosis10.1

Graphical network of the top 20 diseases related to Urticaria Pigmentosa:



Diseases related to urticaria pigmentosa

Symptoms for Urticaria Pigmentosa

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Drugs & Therapeutics for Urticaria Pigmentosa

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Drug clinical trials:

Search ClinicalTrials for Urticaria Pigmentosa

Search NIH Clinical Center for Urticaria Pigmentosa

Genetic Tests for Urticaria Pigmentosa

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Anatomical Context for Urticaria Pigmentosa

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MalaCards organs/tissues related to Urticaria Pigmentosa:

31
Skin, Bone, Bone marrow, Smooth muscle, Thyroid, Testes, Monocytes

Animal Models for Urticaria Pigmentosa or affiliated genes

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MGI Mouse Phenotypes related to Urticaria Pigmentosa:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.8KITLG, KIT, IL2RA
2MP:00053977.9KITLG, KIT, IL2RA, CMA1
3MP:00053877.7CMA1, IL2RA, KIT, KITLG

Publications for Urticaria Pigmentosa

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Articles related to Urticaria Pigmentosa:

(show top 50)    (show all 364)
idTitleAuthorsYear
1
Telangiectasia macularis eruptiva perstans or highly vascularized urticaria pigmentosa? (25439382)
2014
2
Cutaneous mastocytosis in twins: multiple mastocytomas and urticaria pigmentosa in two pairs of monozygotic twins. (21385209)
2011
3
Generalized brownish macules in infancy. Urticaria pigmentosa. (19873965)
2009
4
Anaphylaxis to insect sting associated with urticaria pigmentosa. (12866320)
2003
5
Scabies incognito presenting as urticaria pigmentosa in an infant. (12383096)
2002
6
An infant with urticaria pigmentosa and rickets. (12027094)
2002
7
Acute lymphoblastic leukemia and urticaria pigmentosa in an infant. (10797364)
2000
8
Lack of c-kit mutation in familial urticaria pigmentosa. (10354021)
1999
9
Urticaria pigmentosa: a clinical, hematopathologic, and serologic study of 30 adults. (9495199)
1998
10
Urticaria pigmentosa (mastocytosis). (9707879)
1998
11
Urticaria pigmentosa presenting with massive peripheral eosinophilia. (9263309)
1997
12
Urticaria pigmentosa mimicking xanthoma disseminatum. (20952937)
1995
13
Urticaria pigmentosa and acute lymphoblastic leukaemia. (7562854)
1995
14
Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions. (8144971)
1994
15
Urticaria pigmentosa in monozygotic twins. (8024286)
1994
16
What is your diagnosis? Urticaria pigmentosa. (2222680)
1990
17
Histamine release from skin mast cells and basophils in patients with urticaria pigmentosa. (1690493)
1990
18
Immunohistochemical localization of somatostatin-like immunoreactivity in skin lesions from patients with urticaria pigmentosa. (6206641)
1984
19
A double-blind cross-over study of the effect of ketotifen in urticaria pigmentosa. (6341102)
1983
20
Urticaria pigmentosa. Case presentation and discussion. (915191)
1977
21
Urticaria pigmentosa. (1010614)
1976
22
Juvenile xanthogranuloma and urticaria pigmentosa. (804295)
1975
23
Solitary mast cell tumor. Progression to disseminated urticaria pigmentosa in a negro infant. (4973469)
1969
24
Mastocytosis (urticaria pigmentosa) of skin, stomach, and gut with malabsorption. (6034728)
1967
25
Histamine release from the skin of patients with cutaneous mast cell disease (urticaria pigmentosa). (4162559)
1966
26
Urticaria pigmentosa. Age of onset and prognosis. (13938746)
1962
27
Urticaria pigmentosa, effects of reserpine. (13711436)
1961
28
Urticaria pigmentosa with generalized tissue mastocytosis and blood basophilia. (13794652)
1960
29
Urticaria pigmentosa with visceral and skeletal lesions. (13852143)
1959
30
The remarkable tissue mast cells; with observations on mast cell acid polysaccharides in the cutaneous lesions of urticaria pigmentosa. (13808638)
1959
31
Histamine and related compounds in urticaria pigmentosa: analyses of tissues having mast-cell infiltration. (13542126)
1958
32
Osseous lesions in urticaria pigmentosa. (13388029)
1957
33
Bullous urticaria pigmentosa; summary of literature and report of two cases. (14375388)
1955
34
Urticaria pigmentosa. (13029935)
1953
35
Urticaria pigmentosa associated with bone lesions; a survey and report of eight cases. (12981299)
1952
36
Urticaria pigmentosa. (15433453)
1950
37
Urticaria pigmentosa of 15 years' duration in a woman aged 41. (14770546)
1950
38
Hydroa puerorum? urticaria pigmentosa. (18135864)
1949
39
A case for diagnosis; urticaria pigmentosa? histiocytoma? (18098690)
1948
40
URTICARIA pigmentosa]. (21027907)
1946
41
Urticaria Pigmentosa, Adult Type. (19992934)
1944
42
Urticaria Pigmentosa in an Adult (Telangiectasia Macularis Eruptiva Perstans, Barber and Parkes Weber Type). (19992635)
1943
43
Urticaria Pigmentosa with Unusual Atrophy, in an Adult. (19992636)
1943
44
Urticaria Pigmentosa with Slight Telangiectasia. (19989584)
1933
45
Urticaria Pigmentosa Nodulosa. (19987805)
1930
46
REPORT OF A CASE OF URTICARIA PIGMENTOSA IN A YOUNG ADULT. (18740130)
1926
47
Urticaria Pigmentosa in an Adult. (19982867)
1923
48
Urticaria Pigmentosa. (19980941)
1920
49
Case of Urticaria Pigmentosa. (19980755)
1919
50
Urticaria Pigmentosa of the Macular Type in an Infant. (19974945)
1911

Variations for Urticaria Pigmentosa

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Expression for genes affiliated with Urticaria Pigmentosa

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Search GEO for disease gene expression data for Urticaria Pigmentosa.

Pathways for genes affiliated with Urticaria Pigmentosa

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Pathways related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

(show all 23)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4KIT, IL2RA
29.3KITLG, KIT
39.3KITLG, KIT
4
Show member pathways
Signaling events mediated by Stem cell factor receptor (c-Kit)36
9.3KITLG, KIT
5
Show member pathways
9.3KITLG, KIT
6
Show member pathways
Development EDNRB signaling58
Development ACM2 and ACM4 activation of ERK58
Cell adhesion Integrin inside out signaling58
Development G Proteins mediated regulation MARK ERK signaling58
Signal transduction IP3 signaling58
Development Angiotensin signaling via PYK258
Development EPO induced MAPK pathway58
9.3KITLG, KIT
7
Show member pathways
9.3KITLG, KIT
8
Show member pathways
8.8IL2RA, KIT, KITLG
9
Show member pathways
8.8KITLG, KIT, IL2RA
10
Show member pathways
8.8IL2RA, KIT, KITLG
11
Show member pathways
8.8KITLG, KIT, IL2RA
12
Show member pathways
8.8IL2RA, KIT, KITLG
13
Show member pathways
8.8KITLG, KIT, IL2RA
148.8KITLG, KIT, IL2RA
158.8IL2RA, KIT, KITLG
168.8KITLG, KIT, IL2RA
17
Show member pathways
8.8IL2RA, KIT, KITLG
18
Show member pathways
8.8KITLG, KIT, IL2RA
19
Show member pathways
8.8KITLG, KIT, IL2RA
208.8KITLG, KIT, IL2RA
21
Show member pathways
8.8IL2RA, KIT, KITLG
22
Show member pathways
8.8IL2RA, KIT, KITLG
23
Show member pathways
8.5KITLG, KIT, CMA1

Compounds for genes affiliated with Urticaria Pigmentosa

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Compounds related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

(show all 43)
idCompoundScoreTop Affiliating Genes
12-chlorodeoxyadenosine439.8IL2RA, KIT
2chloroquine43 2 49 28 1213.8KIT, IL2RA
3monochloroacetic acid439.8KITLG, KIT
4vincristine43 49 1211.8KIT, IL2RA
5ag-1296439.8KIT, KITLG
6su5416439.7KITLG, KIT
7toluidine439.7KITLG, KIT
8as 10143 5910.7IL2RA, KITLG
9rhodamine 12343 4910.7KIT, KITLG
10methylcellulose439.7KITLG, KIT
11formaldehyde43 2410.7KIT, IL2RA
12hydroxyurea43 49 1211.7KITLG, KIT
13cytarabine43 49 1211.6KITLG, KIT
14prednisolone43 28 1211.6IL2RA, KITLG
15gold439.6KITLG, KIT
16agarose439.6KIT, KITLG
17herbimycin a43 5910.6KITLG, IL2RA
18imatinib43 49 1211.6KITLG, KIT
19cyclophosphamide43 49 1211.5IL2RA, KITLG
20calcitriol43 59 24 1212.5KITLG, IL2RA
21aspirin43 49 28 2412.5KITLG, IL2RA
22gnrh439.4IL2RA, KITLG
23rantes439.4KITLG, IL2RA
24epinephrine43 24 1211.3KITLG, IL2RA
25polysaccharide439.3KITLG, IL2RA
26gp 130439.2KITLG, KIT, IL2RA
27methotrexate49 43 1211.2IL2RA, KIT, KITLG
28ribonucleic acid439.2KIT, KITLG
295fluorouracil439.2KITLG, KIT, IL2RA
30paclitaxel43 49 1211.2IL2RA, KIT, KITLG
31rapamycin439.2KITLG, KIT, IL2RA
32doxorubicin43 49 1211.2KITLG, KIT, IL2RA
33thymidine43 2410.2KITLG, KIT, IL2RA
34testosterone43 59 24 1212.2KITLG, KIT, IL2RA
35steroid439.2IL2RA, KIT, KITLG
36vegf439.2KITLG, KIT, IL2RA
37phosphatidylinositol439.2IL2RA, KIT, KITLG
38estrogen439.1IL2RA, KIT, KITLG
39cysteine438.9KIT, IL2RA, CMA1
40heparin43 28 24 1211.9CMA1, IL2RA, KITLG
41histamine43 28 2410.4KITLG, KIT, IL2RA, CMA1
42paraffin438.4CMA1, IL2RA, KIT, KITLG
43serine438.2KITLG, KIT, CMA1

GO Terms for genes affiliated with Urticaria Pigmentosa

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Cellular components related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.4KIT, IL2RA

Biological processes related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1ectopic germ cell programmed cell deathGO:00352349.5KITLG, KIT
2embryonic hemopoiesisGO:00351629.5KITLG, KIT
3male gonad developmentGO:00085849.4KITLG, KIT
4phosphatidylinositol-mediated signalingGO:00480159.4KITLG, KIT
5fibroblast growth factor receptor signaling pathwayGO:00085439.3KIT, KITLG
6neurotrophin TRK receptor signaling pathwayGO:00480119.3KITLG, KIT
7Fc-epsilon receptor signaling pathwayGO:00380959.2KITLG, KIT
8epidermal growth factor receptor signaling pathwayGO:00071739.0KITLG, KIT

Products for genes affiliated with Urticaria Pigmentosa

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Sources for Urticaria Pigmentosa

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet