MCID: URT008
MIFTS: 36

Urticaria Pigmentosa malady

Category: Blood diseases

Aliases & Classifications for Urticaria Pigmentosa

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Aliases & Descriptions for Urticaria Pigmentosa:

Name: Urticaria Pigmentosa 10 47 12 36 65
 
Up/mpcm 10

Classifications:



External Ids:

Disease Ontology10 DOID:12309
ICD1027 Q82.2
MeSH36 D014582
NCIt42 C3433
UMLS65 C0042111

Summaries for Urticaria Pigmentosa

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Wikipedia:68 Urticaria pigmentosa (also known as \"Generalized eruption of cutaneous mastocytosis (childhood type)\"... more...

MalaCards based summary: Urticaria Pigmentosa, also known as up/mpcm, is related to plaque-form urticaria pigmentosa and typical urticaria pigmentosa. An important gene associated with Urticaria Pigmentosa is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways are C-MYB transcription factor network and Regulation of KIT signaling. Affiliated tissues include skin, liver and heart.

Related Diseases for Urticaria Pigmentosa

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Graphical network of the top 20 diseases related to Urticaria Pigmentosa:



Diseases related to urticaria pigmentosa

Symptoms for Urticaria Pigmentosa

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Drugs & Therapeutics for Urticaria Pigmentosa

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Ultraviolet (UVA and UVB) Light Therapy in the Treatment of Inflammatory Skin ConditionsTerminatedNCT00129415Phase 1, Phase 2
2Natural History of Urticaria Pigmentosa in ChildrenCompletedNCT00467792
3Cause and Natural Course of Pediatric-Onset MastocytosisCompletedNCT00050193
4Cytokine Production Patterns in Patients With Systemic Mastocytosis Compared With Atopic Dermatitis and Healthy IndividualsCompletedNCT00001760
5Mast Cell Connect: A Registry for Patients With MastocytosisRecruitingNCT02620254
6Study of Factors Regulating Mast Cell ProliferationRecruitingNCT00044122
7Cutaneous Mastocytosis in Children: Analysis of Somatic and Germline MutationsNot yet recruitingNCT02761473

Search NIH Clinical Center for Urticaria Pigmentosa


Cochrane evidence based reviews: urticaria pigmentosa

Genetic Tests for Urticaria Pigmentosa

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Anatomical Context for Urticaria Pigmentosa

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MalaCards organs/tissues related to Urticaria Pigmentosa:

33
Skin, Liver, Heart, Prostate, T cells, Breast, Kidney

Animal Models for Urticaria Pigmentosa or affiliated genes

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MGI Mouse Phenotypes related to Urticaria Pigmentosa:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Urticaria Pigmentosa

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Articles related to Urticaria Pigmentosa:

(show top 50)    (show all 368)
idTitleAuthorsYear
1
Identification of distinct circulating exosomes in Parkinson's disease. (25909081)
2015
2
Activation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signaling. (25535387)
2015
3
Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects. (24217255)
2014
4
High-risk osteoporosis clinic (HiROC): improving osteoporosis and postfracture care with an organized, programmatic approach. (25398432)
2014
5
Focused parathyroidectomy with intraoperative parathyroid hormone monitoring in patients with lithium-associated primary hyperparathyroidism. (23352236)
2013
6
The alterations of matrix metalloproteinase-9 in mouse brainstem during herpes simplex virus type 1-induced facial palsy. (23817985)
2013
7
Bone cement-induced pulmonary embolism in a myeloma patient. (23530982)
2013
8
Is PACAP the major neurotransmitter for stress transduction at the adrenomedullary synapse? (22610912)
2012
9
Insulinoma causing liver metastases 15 years after initial surgery, accompanied by glomerulonephritis. (23243524)
2012
10
Mucoepidermoid carcinoma as a masquerade syndrome of scleral melting and granulomatous kerato-uveitis. (21484645)
2011
11
Ectopic pregnancy: using the hCG ratio to select women for expectant or medical management. (21306315)
2011
12
The clinical assessment of aggressive periodontitis patients. (21811690)
2011
13
Chronic recurrent multifocal osteomyelitis: a case report. (22946018)
2011
14
Optic neuritis and retinal ganglion cell loss in a chronic murine model of multiple sclerosis. (21852980)
2011
15
WITHDRAWN: Haemophilus influenzae oral whole cell vaccination for preventing acute exacerbations of chronic bronchitis. (20927727)
2010
16
DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis. (19272371)
2009
17
Apparently isolated fetal mesocardia at midtrimester: report of a series. (19455586)
2009
18
Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol. (18160712)
2008
19
Gelatin microspheres containing TGF-beta3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture. (18269244)
2008
20
Tailor treatment to the patient in thyrotoxicosis. (17784663)
2007
21
Cardiac tamponade due to rupture of coronary artery fistulas with a giant aneurysm containing a free floating ball thrombus: a case report. (17685030)
2007
22
Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration. (17620058)
2007
23
HIF-1alpha mRNA is not associated with histopathological regression following neoadjuvant chemoradiation in esophageal cancer. (17201171)
2006
24
The role of histopathology in establishing the diagnosis of tuberculous pericardial effusions in the presence of HIV. (16430476)
2006
25
Human granulocytic anaplasmosis and Anaplasma phagocytophilum. (16485466)
2005
26
Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells. (15911146)
2005
27
Procalcitonin as a marker of bacterial infection in the emergency department: an observational study. (14975050)
2004
28
Gene symbol: RYR2. Disease: effort-induced polymorphic ventricular arrhythmias. (15046073)
2004
29
E1A sensitizes cells to tumor necrosis factor alpha by downregulating c-FLIP S. (12552004)
2003
30
Possible role of Marcks in the cellular modulation of monocytic tissue factor-initiated hypercoagulation. (12139748)
2002
31
Regulation of plasminogen activator inhibitor (PAI)-1 expression in a human trophoblast cell line by glucocorticoid (GC) and transforming growth factor (TGF)-beta. (12398812)
2002
32
Substance P induces tumor necrosis factor-alpha release from human skin via mitogen-activated protein kinase. (10854844)
2000
33
Brachial plexus neuropathy as unusual onset of diffuse neurolymphomatosis. (11214664)
2000
34
Posttranscriptional regulation of human leukocyte antigen G during human extravillous cytotrophoblast differentiation. (10819754)
2000
35
Inhibition of microtubule assembly by HPC-1/syntaxin 1A, an exocytosis relating protein. (15216893)
1999
36
The epidemic of orthostatic tachycardia and orthostatic intolerance. (10037110)
1999
37
Hirschsprung's disease: an unusual presentation in pregnancy. (15512276)
1999
38
Blood and tissue fibrinolytic profiles in patients with colorectal carcinoma. (8788547)
1995
39
Monoclonal antibody against PRAD1/cyclin D1 stains nuclei of tumor cells with translocation or amplification at BCL-1 locus. (7961120)
1994
40
Biochemical detection of phaeochromocytoma: should we still be measuring urinary HMMA? (8408698)
1993
41
Oculoglandular syndrome. Cat-scratch disease without the cat scratch. (1561160)
1992
42
Ultrastructure and immunocytochemistry of hepatic peroxisomes in rhizomelic chondrodysplasia punctata. (1468458)
1992
43
Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications. (1413827)
1992
44
Eosinophilia-myalgia syndrome: the Cleveland Clinic experience. (1934454)
1991
45
HB Chicago or alpha (2)136 (H19) Leu----Met beta 2 and a -G gamma-G gamma-globin gene arrangement in a black family. (3781866)
1986
46
Ophthalmologic findings in mucolipidosis III (pseudo-Hurler polydystrophy). (3777077)
1986
47
Posterior interosseous nerve palsy secondary to synovial chondromatosis of the elbow joint. (7252103)
1981
48
Disk diffusion testing of susceptibility of Mycobacterium fortuitum and Mycobacterium chelonei to antibacterial agents. (526002)
1979
49
Early Tahitian views on elephantiasis. (13443422)
1957
50

Variations for Urticaria Pigmentosa

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Expression for genes affiliated with Urticaria Pigmentosa

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Search GEO for disease gene expression data for Urticaria Pigmentosa.

Pathways for genes affiliated with Urticaria Pigmentosa

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GO Terms for genes affiliated with Urticaria Pigmentosa

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Biological processes related to Urticaria Pigmentosa according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of MAP kinase activityGO:004340610.1KIT, KITLG
2phosphatidylinositol-mediated signalingGO:004801510.1KIT, KITLG
3phosphatidylinositol phosphorylationGO:004685410.1KIT, KITLG
4ovarian follicle developmentGO:000154110.0KIT, KITLG
5positive regulation of tyrosine phosphorylation of Stat3 proteinGO:00425179.9IFNA2, KIT
6fibroblast growth factor receptor signaling pathwayGO:00085439.5IL2RA, KIT, KITLG
7positive regulation of GTPase activityGO:00435479.2IL2RA, KIT, KITLG
8activation of MAPKK activityGO:00001869.1IL2RA, KIT, KITLG
9vascular endothelial growth factor receptor signaling pathwayGO:00480109.0IL2RA, KIT, KITLG
10insulin receptor signaling pathwayGO:00082868.8IL2RA, KIT, KITLG
11inflammatory responseGO:00069548.8IFNA2, IL2RA, KIT

Sources for Urticaria Pigmentosa

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet