UIP
MCID: USL001
MIFTS: 52

Usual Interstitial Pneumonia (UIP) malady

Rare diseases category
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Summaries for Usual Interstitial Pneumonia

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Wikipedia:65 Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of... more...

MalaCards based summary: Usual Interstitial Pneumonia, also known as hamman-rich syndrome, is related to desquamative interstitial pneumonia and pneumonia. An important gene associated with Usual Interstitial Pneumonia is CCL7 (chemokine (C-C motif) ligand 7), and among its related pathways are OX40 Pathway and Collagen biosynthesis and modifying enzymes. The compounds sdf 1 and larc have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and bone, and related mouse phenotypes are skeleton and craniofacial.

Aliases & Classifications for Usual Interstitial Pneumonia

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Usual Interstitial Pneumonia, Aliases & Descriptions:

Name: Usual Interstitial Pneumonia 42 62
Hamman-Rich Syndrome 62
 
Uip 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Usual Interstitial Pneumonia

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Diseases related to Usual Interstitial Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1desquamative interstitial pneumonia31.3TNC
2pneumonia31.2SFTPC, IL13, IL8, CCL2, CCL7, SOD3
3interstitial lung disease30.9CCL2
4vascular disease30.7FGF2, IL8, CXCL12, SOD3
5sarcoidosis30.7IFNG, IL13, CCL2
6colitis30.1IFNG, IL8, IL13
7ulcerative colitis30.0IL8, IFNG, CCL7, IL13
8rheumatoid arthritis29.8IL8, IFNG, IL13, CCL2, CXCR4, SERPINH1
9idiopathic pulmonary fibrosis29.5CXCL12, FGF2, IL13, IL8, CCL2, SERPINH1
10pulmonary fibrosis29.5CXCR4, TGFB1, TNC, SFTPC, CCL2, SERPINH1
11arthritis29.4TGFB1, CCL2, IFNG, SOD3, IL8, IL13
12nonspecific interstitial pneumonia10.9
13bronchiolitis obliterans10.5
14bronchiolitis10.5
15lung cancer10.5
16funisitis10.5SERPINH1
17intraocular lymphoma10.5CXCR4
18proliferative glomerulonephritis10.4CCL2
19dentinogenesis imperfecta10.4COL1A1
20bullous keratopathy10.4TNC, SOD3
21whim syndrome10.4CXCR4, CXCL12
22bruton-type agammaglobulinemia10.4CXCL12, CXCR4
23ehlers–danlos syndrome classical type10.4COL1A1, COL3A1
24periapical granuloma10.4CCL2
25aids dementia complex10.4CXCL12, CXCR4
26pulmonary sarcoidosis10.3
27dyskeratosis congenita10.3
28idiopathic interstitial pneumonia10.3
29pulmonary function10.3
30encephalitis10.3CCL2, CXCR4
31fibromatosis, gingival10.3SERPINH1, TGFB1
32pulmonary alveolar proteinosis10.3SFTPC, CCL2
33osteogenesis imperfecta10.3COL3A1, SERPINH1, COL1A1
34nephrosclerosis10.3TGFB1, AGTR1
35lipoid nephrosis10.3CCL2, IL13
36ureteral obstruction10.2AGTR1, TGFB1
37otosclerosis10.2TGFB1, COL1A1
38bacterial vaginosis10.2IL8, SERPINH1
39ureteral disease10.2TGFB1, CCL2
40pulmonary eosinophilia10.2IL13, IL8
41acute myocardial infarction10.2SOD3, AGTR1, TNC
42allergic rhinitis10.2IL13, IL8
43chorioamnionitis10.2SERPINH1, IL8
44bronchiolitis obliterans organizing pneumonia10.2
45asbestosis10.2
46connective tissue disease10.2
47eosinophilic pneumonia10.2
48influenza10.2
49pneumothorax10.2
50sarcoma10.2

Graphical network of the top 20 diseases related to Usual Interstitial Pneumonia:



Diseases related to usual interstitial pneumonia

Symptoms for Usual Interstitial Pneumonia

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Drugs & Therapeutics for Usual Interstitial Pneumonia

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Drug clinical trials:

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Search NIH Clinical Center for Usual Interstitial Pneumonia

Genetic Tests for Usual Interstitial Pneumonia

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Anatomical Context for Usual Interstitial Pneumonia

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MalaCards organs/tissues related to Usual Interstitial Pneumonia:

32
Lung, Bone marrow, Bone, Spleen, Monocytes, B cells, Endothelial

Animal Models for Usual Interstitial Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Usual Interstitial Pneumonia:

36 (show all 20)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.3SERPINH1, SOD3, CXCR4, CCL2, IFNG, COL1A1
2MP:00053828.3TGFB1, SERPINH1, CXCR4, CCL2, IFNG, COL1A1
3MP:00053708.2TGFB1, CXCL12, CCL2, IFNG, COL1A1, COL3A1
4MP:00020068.2SFTPC, TGFB1, CCL2, IFNG, COL1A1, FGF2
5MP:00028738.2TNC, SOD3, CXCL12, CCL2, IFNG, COL1A1
6MP:00053888.1SFTPC, TGFB1, SERPINH1, CXCR4, IFNG, IL13
7MP:00053918.1SFTPC, TGFB1, CCL2, IFNG, COL1A1, FGF2
8MP:00107718.0TGFB1, CCL2, IFNG, IL13, COL1A1, COL3A1
9MP:00053817.9TGFB1, SERPINH1, CXCR4, CCL2, IFNG, IL13
10MP:00053697.7TGFB1, CXCL12, CXCR4, CCL2, IFNG, COL1A1
11MP:00053867.7TNC, TGFB1, CCL2, IFNG, COL1A1, FGF2
12MP:00053897.5SFTPC, TGFB1, CXCL12, CXCR4, CCL2, IFNG
13MP:00053847.4TGFB1, CXCL12, CXCR4, CCL2, IFNG, IL13
14MP:00053787.3CXCR4, SERPINH1, TGFB1, SFTPC, CCL2, IFNG
15MP:00053977.0TGFB1, CXCL12, CXCR4, CCL7, CCL2, IFNG
16MP:00053766.8TNC, TGFB1, SOD3, CXCR4, CCL2, IFNG
17MP:00053876.7SFTPC, TGFB1, SOD3, CXCL12, CXCR4, CCL7
18MP:00036316.6CLDN5, SERPINH1, TGFB1, TNC, CXCL12, CXCR4
19MP:00053856.2FGF2, SFTPC, TGFB1, SERPINH1, CLDN5, CXCL12
20MP:00107685.7CXCL12, CLDN5, SOD3, SERPINH1, TGFB1, SFTPC

Publications for Usual Interstitial Pneumonia

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Articles related to Usual Interstitial Pneumonia:

(show top 50)    (show all 151)
idTitleAuthorsYear
1
Nonspecific interstitial pneumonia and usual interstitial pneumonia: is differentiation possible by high-resolution computed tomography? (24480140)
2014
2
Do you really know precise radiologic-pathologic correlation of usual interstitial pneumonia? (23806534)
2014
3
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
4
HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic. (23840329)
2013
5
Usual interstitial pneumonia: a pattern or a disease? A reflection upon the topic. (23503495)
2013
6
Airspace enlargement with fibrosis shows characteristic histology and immunohistology different from usual interstitial pneumonia, nonspecific interstitial pneumonia and centrilobular emphysema. (23692421)
2013
7
Morbidity and mortality in patients with usual interstitial pneumonia (UIP) pattern undergoing surgery for lung biopsy. (23337301)
2013
8
Usual interstitial pneumonia and nonspecific interstitial pneumonia: correlation between CT findings at the site of biopsy with pathological diagnoses. (22169358)
2012
9
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
10
Pathologic quantification of connective tissue disease-associated versus idiopathic usual interstitial pneumonia. (23020731)
2012
11
Radiological versus histopathological diagnosis of usual interstitial pneumonia in the clinical practice: does it have any survival difference? (19546518)
2010
12
Histopathologic analysis of sixteen autopsy cases of chronic hypersensitivity pneumonitis and comparison with idiopathic pulmonary fibrosis/usual interstitial pneumonia. (19228646)
2009
13
Proliferative activity in fibrosing lung diseases: a comparative study of Ki-67 immunoreactivity in diffuse alveolar damage, bronchiolitis obliterans-organizing pneumonia, and usual interstitial pneumonia. (19368952)
2009
14
Erratum to "Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases" [Hum Pathol 39 (2008) 1275-1294]. (19653362)
2008
15
AKR1B10 in usual interstitial pneumonia: expression in squamous metaplasia in association with smoking and lung cancer. (18358633)
2008
16
Progression of fibrosis in usual interstitial pneumonia: serial evaluation of the native lung after single lung transplantation. (17851227)
2008
17
Unilateral usual interstitial pneumonia associated with sarcoma of the pulmonary artery. (17885035)
2007
18
Morphological and quantitative assessment of mast cells in rheumatoid arthritis associated non-specific interstitial pneumonia and usual interstitial pneumonia. (16611865)
2006
19
Pulmonary sarcoidosis with usual interstitial pneumonia distributed predominantly in the lower lung fields. (16617185)
2006
20
Transbronchial biopsy in usual interstitial pneumonia. (16685001)
2006
21
Differential diagnosis between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) assessed by high-resolution computed tomography (HRCT). (15973221)
2005
22
Pathogenesis and natural history of usual interstitial pneumonia: the whole story or the last chapter of a long novel. (16304243)
2005
23
Fibroblastic foci in usual interstitial pneumonia. (14982825)
2004
24
High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia. (15481270)
2004
25
Respiratory epithelium in usual interstitial pneumonia/idiopathic pulmonary fibrosis: spark or destructive flame? (14695101)
2004
26
Cytokine profile of bronchoalveolar lavage in systemic sclerosis with interstitial lung disease: comparison with usual interstitial pneumonia. (15194596)
2004
27
The elusive goal of therapy for usual interstitial pneumonia. (14711919)
2004
28
High serum concentrations of surfactant protein A in usual interstitial pneumonia compared with non-specific interstitial pneumonia. (12511721)
2003
29
Nonspecific interstitial pneumonia in collagen vascular diseases: comparison of the clinical characteristics and prognostic significance with usual interstitial pneumonia. (14620168)
2003
30
Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. (14555549)
2003
31
Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. (14595745)
2003
32
BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia. (12952254)
2003
33
Usual interstitial pneumonia: histologic study of biopsy and explant specimens. (12459623)
2002
34
Histopathology and prediction of survival in usual interstitial pneumonia. (12016111)
2002
35
Survival of patients with biopsy-proven usual interstitial pneumonia and nonspecific interstitial pneumonia. (12108865)
2002
36
Three-dimensional analysis of alveolar structure in usual interstitial pneumonia. (12111200)
2002
37
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparative appearances at and diagnostic accuracy of thin-section CT. (11719652)
2001
38
Pulmonary (99m)Tc-DTPA aerosol clearance and survival in usual interstitial pneumonia (UIP). (11713353)
2001
39
Fibroblast contractility: usual interstitial pneumonia and nonspecific interstitial pneumonia. (11112149)
2000
40
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis. (10471616)
1999
41
Usual interstitial pneumonia: relationship between disease activity and the progression of honeycombing at thin-section computed tomography. (9671423)
1998
42
Histopathological features of pulmonary asbestosis with particular emphasis on the comparison with those of usual interstitial pneumonia. (9540344)
1997
43
Colchicine versus prednisone as treatment of usual interstitial pneumonia. (9070193)
1997
44
Usual interstitial pneumonia. Quantitative assessment of high-resolution computed tomography findings by computer-assisted texture-based image analysis. (9291045)
1997
45
Usual interstitial pneumonia associated with primary SjAPgren's syndrome. (7497800)
1995
46
Mortality in Mexican patients with chronic pigeon breeder's lung compared with those with usual interstitial pneumonia. (8317813)
1993
47
Usual interstitial pneumonia: correlation of CT with clinical, functional, and radiologic findings. (3797650)
1987
48
A comparison of bronchiolitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airways disease. (3826896)
1987
49
Radiographic manifestations of bronchiolitis obliterans with organizing pneumonia vs usual interstitial pneumonia. (3490161)
1986
50
Bronchiolitis obliterans and usual interstitial pneumonia. A comparative clinicopathologic study. (3717494)
1986

Variations for Usual Interstitial Pneumonia

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Expression for genes affiliated with Usual Interstitial Pneumonia

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Expression patterns in normal tissues for genes affiliated with Usual Interstitial Pneumonia

Search GEO for disease gene expression data for Usual Interstitial Pneumonia.

Pathways for genes affiliated with Usual Interstitial Pneumonia

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Pathways related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 41)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7IL13, IFNG
2
Show member pathways
9.7COL3A1, COL1A1, SERPINH1
39.6IL13, TGFB1
49.4COL3A1, COL1A1, IFNG
5
Show member pathways
thioredoxin pathway37
9.4SOD3, CCL2, IFNG
6
Show member pathways
Development EDNRB signaling60
Development ACM2 and ACM4 activation of ERK60
Cell adhesion Integrin inside out signaling60
Development G Proteins mediated regulation MARK ERK signaling60
Signal transduction IP3 signaling60
Development Angiotensin signaling via PYK260
Development EPO induced MAPK pathway60
9.3AGTR1, COL1A1, CXCR4, CXCL12
79.2FGF2, CXCR4, CXCL12, TNC
89.2IFNG, IL8, IL13
99.2IL13, IL8, IFNG
109.2FGF2, SERPINH1, TGFB1
119.2TNC, COL1A1, COL3A1, FGF2
129.2TGFB1, CXCR4, FGF2
13
Show member pathways
Proteogylcan syndecan-mediated signaling events37
9.1FGF2, TGFB1, TNC
149.1TNC, TGFB1, FGF2
159.1CLDN5, CXCL12, CXCR4
16
Show member pathways
9.1COL3A1, COL1A1, IL8, TNC
17
Show member pathways
9.0IL13, IFNG, TGFB1
189.0TGFB1, IFNG, IL13
199.0IL13, IFNG, TGFB1
20
Show member pathways
8.9CXCL12, CXCR4, CCL7, CCL2, IL8
21
Show member pathways
8.9CXCL12, CXCR4, CCL7, CCL2, IL8
22
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.9FGF2, AGTR1, IFNG, CCL2
23
Show member pathways
8.8IL13, IL8, IFNG, CCL2
24
Show member pathways
8.6CXCL12, CXCR4, CCL7, CCL2, IL8, AGTR1
25
Show member pathways
8.5TGFB1, CXCL12, CXCR4, IFNG, IL13
268.5TGFB1, CCL2, IFNG, IL8
278.5TGFB1, CCL2, IFNG, IL8
28
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.5TGFB1, CCL2, IFNG, IL8
29
Show member pathways
8.3TNC, TGFB1, SERPINH1, COL1A1, COL3A1, FGF2
30
Show member pathways
8.3TNC, TGFB1, CXCL12, COL1A1, COL3A1, FGF2
31
Show member pathways
8.3TGFB1, CXCL12, CCL7, CCL2, AGTR1, FGF2
328.3TGFB1, IFNG, IL8, COL1A1, COL3A1
338.3TGFB1, IFNG, IL8, COL1A1, COL3A1
348.2TGFB1, CXCL12, CCL2, IFNG, IL8
35
Show member pathways
7.6IL13, IL8, CCL2, CCL7, CXCR4, CXCL12
36
Show member pathways
7.6TGFB1, FGF2, IL13, IL8, CCL2, CCL7
37
Show member pathways
7.5TGFB1, CXCL12, CXCR4, CCL7, CCL2, IFNG
38
Show member pathways
7.0TGFB1, AKR1B10, CXCL12, CXCR4, CCL7, CCL2
39
Show member pathways
6.8TGFB1, CXCL12, CXCR4, CCL7, CCL2, IFNG
40
Show member pathways
6.7CXCR4, CXCL12, TGFB1, TNC, CCL7, CCL2
41
Show member pathways
6.6COL3A1, TNC, TGFB1, CLDN5, CXCL12, CXCR4

Compounds for genes affiliated with Usual Interstitial Pneumonia

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Compounds related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 172)
idCompoundScoreTop Affiliating Genes
1sdf 1449.8CXCL12, CCL2, CXCR4
2larc449.7CCL7, CXCR4, CXCL12, CCL2
3mcp 1449.5IL8, CCL2, CCL7, CXCR4
4ccl444 2810.5CXCR4, IL13, CCL2, CCL7, CXCL12
5anaphylatoxin449.3CXCL12, IL8, CCL2, CCL7, CXCR4
6groalpha449.3IL13, CCL2, CCL7, CXCL12, IL8
7il-12449.2IL13, CCL2, IFNG, IL8
8heparan sulfate44 2410.2FGF2, CXCR4, CXCL12, TNC, SOD3
9grobeta449.1CCL2, IL8, CXCL12
10procollagen449.1COL1A1, SERPINH1, TNC, COL3A1, TGFB1
11fmlp449.0IL13, CCL2, CCL7, CXCL12, IL8
12glycosaminoglycan448.8FGF2, CXCL12, TNC, COL1A1, TGFB1
13methacholine44 50 1110.8TGFB1, IL8, IL13, AGTR1
14bleomycin44 119.7IL13, FGF2, TGFB1, COL1A1, SFTPC, CCL2
15simvastatin44 50 61 28 24 1113.6IFNG, CCL2, AGTR1, IL8, COL1A1
16ribonucleic acid448.6COL3A1, CXCL12, SFTPC, TGFB1, CCL7, COL1A1
17gm-csf44 289.6IL13, TGFB1, CCL2, IFNG, IL8
18il 10448.6IL8, IFNG, CCL2, TGFB1, IL13
19cytochalasin d44 619.6FGF2, IL8, CCL2, CXCL12, TGFB1
20herbimycin a44 619.6CXCL12, CXCR4, FGF2, CCL2, IL8, IFNG
21tarc448.6IL13, CXCL12, CXCR4, CCL7, CCL2, IFNG
22ccl344 289.6IL13, IL8, IFNG, CCL2, CCL7, CXCR4
23polysaccharide448.6CXCR4, FGF2, IL13, CCL2, CXCL12, TGFB1
24tgf beta1448.6TGFB1, IL13, TNC, CCL2, AGTR1, FGF2
25hyaluronic acid44 249.5FGF2, TNC, CXCL12, IL8, IL13, TGFB1
26matrigel448.5TNC, IL8, CXCR4, CXCL12, TGFB1, FGF2
27oxygen44 249.5AGTR1, IL8, CCL2, CCL7, CXCR4, CXCL12
28heparin44 28 24 1111.4CXCL12, IL8, SOD3, TNC, FGF2, IL13
29genistein44 28 61 2 24 1113.3CXCL12, CCL7, IL8, FGF2, AGTR1, IFNG
30pd 98,059448.2CCL2, IL8, CXCR4, CXCL12, TGFB1, IL13
31phosphatidylinositol448.2FGF2, AGTR1, IL13, CCL2, TNC, CXCR4
32histamine44 28 2410.1CCL2, IFNG, CCL7, IL13, IL8, TGFB1
33thymidine44 249.1COL3A1, TGFB1, CXCL12, IFNG, IL13, COL1A1
34nitric oxide44 24 1110.1AGTR1, IL13, CXCR4, CCL2, SERPINH1, SOD3
35arginine448.1SOD3, CXCL12, CXCR4, SFTPC, CCL2, IL13
36cysteine448.0SFTPC, TNC, SOD3, IFNG, IL8, COL1A1
37alanine448.0AGTR1, COL1A1, IL13, SOD3, TGFB1, CXCR4
38estrogen447.9AGTR1, COL1A1, IL13, CXCR4, TGFB1, CXCL12
39ly294002447.9CCL2, IL13, IL8, CXCR4, CXCL12, TGFB1
40rantes447.9TGFB1, IL13, IL8, CCL2, CCL7, CXCR4
41oligonucleotide447.8TNC, TGFB1, COL1A1, SERPINH1, CLDN5, CXCR4
42retinoic acid44 248.8SFTPC, TNC, TGFB1, CXCR4, IFNG, COL1A1
43cyclosporin a44 28 619.6CXCR4, SERPINH1, TGFB1, IL8, IL13, COL3A1
44sb 20358044 618.4TGFB1, CXCR4, CCL2, IFNG, AGTR1, IL8
45pge2447.4CXCR4, COL1A1, IL13, IL8, CCL2, TGFB1
46actinomycin d446.7IFNG, CXCL12, TNC, SFTPC, TGFB1, CCL2
47cycloheximide446.7CXCL12, CXCR4, TNC, TGFB1, CCL2, IFNG
48serine446.6TNC, TGFB1, SERPINH1, CXCL12, CXCR4, CCL7
49dexamethasone44 50 28 119.4CCL2, TGFB1, TNC, SFTPC, IFNG, COL1A1
50vegf446.1SFTPC, TNC, TGFB1, SERPINH1, IL8, SOD3

GO Terms for genes affiliated with Usual Interstitial Pneumonia

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Cellular components related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum lumenGO:0057889.7COL3A1, COL1A1, SERPINH1
2extracellular matrixGO:0310129.3TNC, SOD3, COL1A1, COL3A1
3external side of plasma membraneGO:0098978.9IL13, IFNG, CXCR4, CXCL12
4extracellular spaceGO:0056155.9FGF2, SFTPC, TNC, TGFB1, SERPINH1, SOD3
5extracellular regionGO:0055765.7CXCL12, AKR1B10, SOD3, TGFB1, TNC, CCL7

Biological processes related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 47)
idNameGO IDScoreTop Affiliating Genes
1ameboidal cell migrationGO:00166710.3CXCR4, CXCL12
2collagen biosynthetic processGO:03296410.3SERPINH1, COL1A1
3T cell proliferationGO:04209810.2CXCL12, CXCR4
4neutrophil activationGO:04211910.1IL8, CXCR4
5cellular response to cytokine stimulusGO:07134510.1IL13, CXCR4
6monocyte chemotaxisGO:00254810.1CCL7, CCL2
7collagen fibril organizationGO:03019910.1COL3A1, COL1A1, SERPINH1
8motor neuron axon guidanceGO:00804510.1CXCR4, CXCL12
9induction of positive chemotaxisGO:05093010.1IL8, CXCL12
10cellular response to mechanical stimulusGO:07126010.0SFTPC, IL13, COL1A1
11chemokine-mediated signaling pathwayGO:07009810.0CCL2, CXCR4, CXCL12
12negative regulation of immune responseGO:05077710.0TGFB1, COL3A1
13wound healingGO:0420609.9TNC, COL3A1, FGF2
14response to ethanolGO:0454719.9IL13, CCL2, TNC
15positive regulation of cellular protein metabolic processGO:0322709.9TGFB1, AGTR1
16calcium-mediated signalingGO:0197229.8AGTR1, IL8, CXCR4
17positive regulation of endothelial cell proliferationGO:0019389.8FGF2, CCL2, CXCL12
18cellular response to fibroblast growth factor stimulusGO:0443449.8CCL2, IL8
19response to radiationGO:0093149.8COL3A1, CXCL12, TGFB1
20negative regulation of blood vessel endothelial cell migrationGO:0435379.8TGFB1, FGF2
21germ cell migrationGO:0083549.8TGFB1, CXCL12, CXCR4
22hyaluronan catabolic processGO:0302149.8TGFB1, FGF2
23response to mechanical stimulusGO:0096129.7COL3A1, CCL2, CXCL12, TNC
24response to virusGO:0096159.7CXCL12, CXCR4, IFNG
25positive regulation of blood vessel endothelial cell migrationGO:0435369.7TGFB1, FGF2
26organ regenerationGO:0311009.6TGFB1, CXCL12, CCL2
27immune responseGO:0069559.6IL13, IL8, CCL7, CXCL12
28digestive tract developmentGO:0485659.6COL3A1, TGFB1
29positive regulation of cell migrationGO:0303359.6TGFB1, CCL7, COL1A1
30cellular component movementGO:0069289.6IFNG, IL8, IL13
31positive regulation of protein secretionGO:0507149.6IL13, TGFB1
32agingGO:0075689.6COL3A1, CCL2, TGFB1
33neutrophil chemotaxisGO:0305939.5CCL2, IFNG, IL8
34transforming growth factor beta receptor signaling pathwayGO:0071799.5COL3A1, CCL2, TGFB1
35cellular response to lipopolysaccharideGO:0712229.5IL8, IFNG, CCL2
36endoplasmic reticulum unfolded protein responseGO:0309689.5CCL2, IFNG, IL8
37cellular calcium ion homeostasisGO:0068749.5CCL2, CCL7, CXCL12, TGFB1
38positive regulation of epithelial to mesenchymal transitionGO:0107189.4COL1A1, TGFB1
39protein import into nucleus, translocationGO:0000609.4TGFB1, IFNG
40G-protein coupled receptor signaling pathwayGO:0071869.2CXCL12, CXCR4, CCL2, IL8, AGTR1
41chemotaxisGO:0069359.2FGF2, IL8, CCL2, CCL7, CXCL12
42response to hypoxiaGO:0016669.2TGFB1, SOD3, CXCL12, CXCR4, CCL2
43positive regulation of phosphatidylinositol 3-kinase activityGO:0435529.1FGF2, TGFB1
44cell cycle arrestGO:0070509.1IL8, IFNG, TGFB1
45signal transductionGO:0071658.9FGF2, IL13, IL8, CCL2, CCL7, CXCL12
46extracellular matrix organizationGO:0301988.8TNC, TGFB1, SERPINH1, COL1A1, COL3A1, FGF2
47inflammatory responseGO:0069548.7TGFB1, CXCR4, CCL7, CCL2, IL8, IL13

Molecular functions related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1CCR2 chemokine receptor bindingGO:03172710.0CCL2, CCL7
2platelet-derived growth factor bindingGO:0484079.8COL1A1, COL3A1
3heparin bindingGO:0082019.4SOD3, CCL7, CCL2, FGF2
4chemokine activityGO:0080099.3IL8, CCL2, CCL7, CXCL12
5cytokine activityGO:0051259.3FGF2, IL13, IFNG
6growth factor activityGO:0080838.9FGF2, CXCL12, TGFB1
7protein bindingGO:0055156.6SFTPC, TGFB1, SOD3, AKR1B10, CXCR4, IL8

Products for genes affiliated with Usual Interstitial Pneumonia

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  • Antibodies
  • Proteins
  • Lysates

Sources for Usual Interstitial Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet