UIP
MCID: USL001
MIFTS: 51

Usual Interstitial Pneumonia (UIP) malady

Rare diseases category
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Summaries for Usual Interstitial Pneumonia

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65Wikipedia, 33MalaCards
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Wikipedia:65 Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of... more...

MalaCards: Usual Interstitial Pneumonia, also known as hamman-rich syndrome, is related to pneumonia and idiopathic pulmonary fibrosis. An important gene associated with Usual Interstitial Pneumonia is CCL7 (chemokine (C-C motif) ligand 7), and among its related pathways are OX40 Pathway and Collagen biosynthesis and modifying enzymes. The compounds sdf 1 and larc have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and bone, and related mouse phenotypes are skeleton and craniofacial.

Aliases & Classifications for Usual Interstitial Pneumonia

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62UMLS, 43NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

usual interstitial pneumonia 43
hamman-rich syndrome 62
uip 43


Related Diseases for Usual Interstitial Pneumonia

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17GeneCards, 18GeneDecks
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Diseases related to Usual Interstitial Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 121)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.7SFTPC, TGFB1, SOD3, CCL7, CCL2, IL8
2idiopathic pulmonary fibrosis30.8FGF2, IL13, IL8, IFNG, SFTPC, TNC
3pulmonary fibrosis30.7SFTPC, TNC, TGFB1, SERPINH1, SOD3, CXCL12
4interstitial lung disease30.7CCL2
5vascular disease30.7FGF2, IL8, CXCL12, SOD3
6sarcoidosis30.7IL13, IFNG, CCL2
7rheumatoid arthritis30.6SERPINH1, SOD3, CXCL12, CXCR4, CCL2, IFNG
8arthritis30.5TGFB1, SOD3, CCL2, IFNG, IL8, IL13
9desquamative interstitial pneumonia30.4TNC
10ulcerative colitis30.2CCL7, IFNG, IL8, IL13
11nonspecific interstitial pneumonia10.9
12bronchiolitis10.5
13bronchiolitis obliterans10.5
14lung cancer10.5
15dyskeratosis congenita10.3
16idiopathic interstitial pneumonia10.3
17bronchiolitis obliterans organizing pneumonia10.2
18asbestosis10.2
19pulmonary sarcoidosis10.2
20connective tissue disease10.2
21eosinophilic pneumonia10.2
22influenza10.2
23pneumothorax10.2
24sarcoma10.2
25scleroderma10.2
26spontaneous pneumothorax10.2
27cytomegalovirus infection10.2
28pulmonary function10.2
29funisitis10.1SERPINH1
30intraocular lymphoma10.1CXCR4
31proliferative glomerulonephritis10.1CCL2
32dentinogenesis imperfecta10.1COL1A1
33bullous keratopathy10.1TNC, SOD3
34whim syndrome10.1CXCR4, CXCL12
35agammaglobulinemia10.1CXCR4, CXCL12
36ehlers–danlos syndrome classical type10.1COL1A1, COL3A1
37periapical granuloma10.1CCL2
38aids dementia complex10.1CXCL12, CXCR4
39encephalitis10.1CCL2, CXCR4
40fibromatosis, gingival10.1TGFB1, SERPINH1
41pulmonary alveolar proteinosis10.1SFTPC, CCL2
42osteogenesis imperfecta10.1SERPINH1, COL1A1, COL3A1
43lipoid nephrosis10.1CCL2, IL13
44nephrosclerosis10.1TGFB1, AGTR1
45ureteral obstruction10.1TGFB1, AGTR1
46otosclerosis10.1TGFB1, COL1A1
47bacterial vaginosis10.1SERPINH1, IL8
48ureteral disease10.0TGFB1, CCL2
49pulmonary eosinophilia10.0IL8, IL13
50acute myocardial infarction10.0TNC, SOD3, AGTR1

Graphical network of the top 20 diseases related to Usual Interstitial Pneumonia:



Diseases related to usual interstitial pneumonia

Symptoms for Usual Interstitial Pneumonia

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Drugs & Therapeutics for Usual Interstitial Pneumonia

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Usual Interstitial Pneumonia

Search NIH Clinical Center for Usual Interstitial Pneumonia

Genetic Tests for Usual Interstitial Pneumonia

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Anatomical Context for Usual Interstitial Pneumonia

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33MalaCards
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MalaCards organs/tissues related to Usual Interstitial Pneumonia:

33
Lung, Bone marrow, Bone, Spleen, Monocytes, B cells

Animal Models for Usual Interstitial Pneumonia or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Usual Interstitial Pneumonia:

37 (show all 20)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.3SERPINH1, SOD3, CXCR4, CCL2, IFNG, COL1A1
2MP:00053828.3CCL2, TGFB1, COL1A1, IFNG, CXCR4, SERPINH1
3MP:00053708.2COL1A1, COL3A1, IFNG, CCL2, CXCL12, TGFB1
4MP:00020068.2FGF2, SFTPC, TGFB1, CCL2, IFNG, COL1A1
5MP:00028738.2SOD3, COL1A1, IFNG, CCL2, CXCL12, TNC
6MP:00053888.1IL13, IFNG, CXCR4, TGFB1, COL3A1, SFTPC
7MP:00053918.1TGFB1, FGF2, COL1A1, IFNG, CCL2, SFTPC
8MP:00107718.0IFNG, COL3A1, IL13, CCL2, TGFB1, COL1A1
9MP:00053817.9IL13, COL1A1, IFNG, CCL2, COL3A1, TGFB1
10MP:00053697.7COL3A1, COL1A1, IFNG, CCL2, CXCR4, CXCL12
11MP:00053867.7FGF2, TNC, SFTPC, CCL2, IFNG, COL1A1
12MP:00053897.5FGF2, CCL2, COL1A1, IL13, IFNG, CXCR4
13MP:00053847.4CCL2, IL13, IFNG, FGF2, CXCL12, COL1A1
14MP:00053787.3CCL2, IL13, AGTR1, SFTPC, SERPINH1, TGFB1
15MP:00053977.0CXCL12, FGF2, COL1A1, IL8, IFNG, CCL2
16MP:00053766.8TGFB1, FGF2, AGTR1, COL3A1, COL1A1, IL13
17MP:00053876.7IFNG, CXCR4, CCL7, CCL2, AGTR1, COL1A1
18MP:00036316.6TGFB1, CLDN5, CXCL12, CXCR4, CCL2, IFNG
19MP:00053856.2IFNG, COL3A1, FGF2, COL1A1, CCL2, CXCL12
20MP:00107685.7CXCL12, CXCR4, IFNG, CLDN5, SOD3, SERPINH1

Publications for Usual Interstitial Pneumonia

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52PubMed
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Articles related to Usual Interstitial Pneumonia:

(show top 50)    (show all 135)
idTitleAuthorsYear
1
Do you really know precise radiologic-pathologic correlation of usual interstitial pneumonia? (23806534)
2014
2
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
3
HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic. (23840329)
2013
4
Usual interstitial pneumonia: a pattern or a disease? A reflection upon the topic. (23503495)
2013
5
Airspace enlargement with fibrosis shows characteristic histology and immunohistology different from usual interstitial pneumonia, nonspecific interstitial pneumonia and centrilobular emphysema. (23692421)
2013
6
Morbidity and mortality in patients with usual interstitial pneumonia (UIP) pattern undergoing surgery for lung biopsy. (23337301)
2013
7
Usual interstitial pneumonia and nonspecific interstitial pneumonia: correlation between CT findings at the site of biopsy with pathological diagnoses. (22169358)
2012
8
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
9
Pathologic quantification of connective tissue disease-associated versus idiopathic usual interstitial pneumonia. (23020731)
2012
10
Radiological versus histopathological diagnosis of usual interstitial pneumonia in the clinical practice: does it have any survival difference? (19546518)
2010
11
Histopathologic analysis of sixteen autopsy cases of chronic hypersensitivity pneumonitis and comparison with idiopathic pulmonary fibrosis/usual interstitial pneumonia. (19228646)
2009
12
Proliferative activity in fibrosing lung diseases: a comparative study of Ki-67 immunoreactivity in diffuse alveolar damage, bronchiolitis obliterans-organizing pneumonia, and usual interstitial pneumonia. (19368952)
2009
13
Erratum to "Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases" [Hum Pathol 39 (2008) 1275-1294]. (19653362)
2008
14
AKR1B10 in usual interstitial pneumonia: expression in squamous metaplasia in association with smoking and lung cancer. (18358633)
2008
15
Progression of fibrosis in usual interstitial pneumonia: serial evaluation of the native lung after single lung transplantation. (17851227)
2008
16
Usual interstitial pneumonia in an adolescent with ABCA3 mutations. (18628224)
2008
17
Unilateral usual interstitial pneumonia associated with sarcoma of the pulmonary artery. (17885035)
2007
18
Morphological and quantitative assessment of mast cells in rheumatoid arthritis associated non-specific interstitial pneumonia and usual interstitial pneumonia. (16611865)
2006
19
Pulmonary sarcoidosis with usual interstitial pneumonia distributed predominantly in the lower lung fields. (16617185)
2006
20
Transbronchial biopsy in usual interstitial pneumonia. (16685001)
2006
21
Differential diagnosis between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) assessed by high-resolution computed tomography (HRCT). (15973221)
2005
22
Pathogenesis and natural history of usual interstitial pneumonia: the whole story or the last chapter of a long novel. (16304243)
2005
23
Fibroblastic foci in usual interstitial pneumonia. (14982825)
2004
24
High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia. (15481270)
2004
25
Respiratory epithelium in usual interstitial pneumonia/idiopathic pulmonary fibrosis: spark or destructive flame? (14695101)
2004
26
Cytokine profile of bronchoalveolar lavage in systemic sclerosis with interstitial lung disease: comparison with usual interstitial pneumonia. (15194596)
2004
27
The elusive goal of therapy for usual interstitial pneumonia. (14711919)
2004
28
High serum concentrations of surfactant protein A in usual interstitial pneumonia compared with non-specific interstitial pneumonia. (12511721)
2003
29
Nonspecific interstitial pneumonia in collagen vascular diseases: comparison of the clinical characteristics and prognostic significance with usual interstitial pneumonia. (14620168)
2003
30
Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. (14555549)
2003
31
Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. (14595745)
2003
32
BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia. (12952254)
2003
33
Usual interstitial pneumonia: histologic study of biopsy and explant specimens. (12459623)
2002
34
Histopathology and prediction of survival in usual interstitial pneumonia. (12016111)
2002
35
Survival of patients with biopsy-proven usual interstitial pneumonia and nonspecific interstitial pneumonia. (12108865)
2002
36
Three-dimensional analysis of alveolar structure in usual interstitial pneumonia. (12111200)
2002
37
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparative appearances at and diagnostic accuracy of thin-section CT. (11719652)
2001
38
Pulmonary (99m)Tc-DTPA aerosol clearance and survival in usual interstitial pneumonia (UIP). (11713353)
2001
39
Fibroblast contractility: usual interstitial pneumonia and nonspecific interstitial pneumonia. (11112149)
2000
40
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis. (10471616)
1999
41
Usual interstitial pneumonia: relationship between disease activity and the progression of honeycombing at thin-section computed tomography. (9671423)
1998
42
Histopathological features of pulmonary asbestosis with particular emphasis on the comparison with those of usual interstitial pneumonia. (9540344)
1997
43
Colchicine versus prednisone as treatment of usual interstitial pneumonia. (9070193)
1997
44
Usual interstitial pneumonia. Quantitative assessment of high-resolution computed tomography findings by computer-assisted texture-based image analysis. (9291045)
1997
45
Usual interstitial pneumonia associated with primary SjAPgren's syndrome. (7497800)
1995
46
Mortality in Mexican patients with chronic pigeon breeder's lung compared with those with usual interstitial pneumonia. (8317813)
1993
47
Usual interstitial pneumonia: correlation of CT with clinical, functional, and radiologic findings. (3797650)
1987
48
A comparison of bronchiolitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airways disease. (3826896)
1987
49
Radiographic manifestations of bronchiolitis obliterans with organizing pneumonia vs usual interstitial pneumonia. (3490161)
1986
50
Bronchiolitis obliterans and usual interstitial pneumonia. A comparative clinicopathologic study. (3717494)
1986

Variations for Usual Interstitial Pneumonia

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Expression for genes affiliated with Usual Interstitial Pneumonia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Usual Interstitial Pneumonia

Search GEO for disease gene expression data for Usual Interstitial Pneumonia.

Pathways for genes affiliated with Usual Interstitial Pneumonia

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Sources:
50PathCards, 53QIAGEN, 55Reactome, 54R&D Systems, 38NCBI BioSystems Database, 60Thomson Reuters, 30KEGG, 5Cell Signaling Technology, 12EMD Millipore
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Pathways related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 41)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7IL13, IFNG
2
Show member pathways
9.7COL3A1, COL1A1, SERPINH1
39.6IL13, TGFB1
49.4COL3A1, COL1A1, IFNG
5
Show member pathways
thioredoxin pathway38
9.4SOD3, CCL2, IFNG
6
Show member pathways
Development EDNRB signaling60
Development ACM2 and ACM4 activation of ERK60
Cell adhesion Integrin inside out signaling60
Development G Proteins mediated regulation MARK ERK signaling60
Signal transduction IP3 signaling60
Development Angiotensin signaling via PYK260
Development EPO induced MAPK pathway60
9.3AGTR1, COL1A1, CXCR4, CXCL12
79.2FGF2, CXCR4, CXCL12, TNC
89.2IFNG, IL8, IL13
99.2IL13, IL8, IFNG
109.2FGF2, SERPINH1, TGFB1
119.2TNC, COL1A1, COL3A1, FGF2
129.2TGFB1, CXCR4, FGF2
13
Show member pathways
Proteogylcan syndecan-mediated signaling events38
9.1FGF2, TGFB1, TNC
149.1TNC, TGFB1, FGF2
159.1CLDN5, CXCL12, CXCR4
16
Show member pathways
9.1COL3A1, COL1A1, IL8, TNC
17
Show member pathways
9.0IL13, IFNG, TGFB1
189.0TGFB1, IFNG, IL13
199.0IL13, IFNG, TGFB1
20
Show member pathways
8.9CXCL12, CXCR4, CCL7, CCL2, IL8
21
Show member pathways
8.9CXCL12, CXCR4, CCL7, CCL2, IL8
22
Show member pathways
IL23-mediated signaling events38
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling38
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.9FGF2, AGTR1, IFNG, CCL2
23
Show member pathways
8.8IL13, IL8, IFNG, CCL2
24
Show member pathways
8.6CXCL12, CXCR4, CCL7, CCL2, IL8, AGTR1
25
Show member pathways
8.5TGFB1, CXCL12, CXCR4, IFNG, IL13
268.5TGFB1, CCL2, IFNG, IL8
278.5TGFB1, CCL2, IFNG, IL8
28
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
8.5TGFB1, CCL2, IFNG, IL8
29
Show member pathways
8.3TNC, TGFB1, SERPINH1, COL1A1, COL3A1, FGF2
30
Show member pathways
8.3TNC, TGFB1, CXCL12, COL1A1, COL3A1, FGF2
31
Show member pathways
8.3TGFB1, CXCL12, CCL7, CCL2, AGTR1, FGF2
328.3TGFB1, IFNG, IL8, COL1A1, COL3A1
338.3TGFB1, IFNG, IL8, COL1A1, COL3A1
348.2TGFB1, CXCL12, CCL2, IFNG, IL8
35
Show member pathways
7.6IL13, IL8, CCL2, CCL7, CXCR4, CXCL12
36
Show member pathways
7.6TGFB1, FGF2, IL13, IL8, CCL2, CCL7
37
Show member pathways
7.5TGFB1, CXCL12, CXCR4, CCL7, CCL2, IFNG
38
Show member pathways
7.0TGFB1, AKR1B10, CXCL12, CXCR4, CCL7, CCL2
39
Show member pathways
6.8TGFB1, CXCL12, CXCR4, CCL7, CCL2, IFNG
40
Show member pathways
6.7CXCR4, CXCL12, TGFB1, TNC, CCL7, CCL2
41
Show member pathways
6.6COL3A1, TNC, TGFB1, CLDN5, CXCL12, CXCR4

Compounds for genes affiliated with Usual Interstitial Pneumonia

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Sources:
45Novoseek, 29IUPHAR, 24HMDB, 51PharmGKB, 11DrugBank, 61Tocris Bioscience, 3BitterDB
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Compounds related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 172)
idCompoundScoreTop Affiliating Genes
1sdf 1459.8CXCL12, CCL2, CXCR4
2larc459.7CCL7, CXCR4, CXCL12, CCL2
3mcp 1459.5IL8, CCL2, CCL7, CXCR4
4ccl445 2910.5CXCR4, IL13, CCL2, CCL7, CXCL12
5anaphylatoxin459.3CXCL12, IL8, CCL2, CCL7, CXCR4
6groalpha459.3IL13, CCL2, CCL7, CXCL12, IL8
7il-12459.2IL13, CCL2, IFNG, IL8
8heparan sulfate45 2410.2FGF2, CXCR4, CXCL12, TNC, SOD3
9grobeta459.1CCL2, IL8, CXCL12
10procollagen459.1COL1A1, SERPINH1, TNC, COL3A1, TGFB1
11fmlp459.0IL13, CCL2, CCL7, CXCL12, IL8
12glycosaminoglycan458.8FGF2, CXCL12, TNC, COL1A1, TGFB1
13methacholine45 51 1110.8TGFB1, IL8, IL13, AGTR1
14bleomycin45 119.7IL13, FGF2, TGFB1, COL1A1, SFTPC, CCL2
15simvastatin45 51 61 29 24 1113.6IFNG, CCL2, AGTR1, IL8, COL1A1
16ribonucleic acid458.6COL3A1, CXCL12, SFTPC, TGFB1, CCL7, COL1A1
17gm-csf45 299.6IL13, TGFB1, CCL2, IFNG, IL8
18il 10458.6IL8, IFNG, CCL2, TGFB1, IL13
19cytochalasin d45 619.6FGF2, IL8, CCL2, CXCL12, TGFB1
20herbimycin a45 619.6CXCL12, CXCR4, FGF2, CCL2, IL8, IFNG
21tarc458.6IL13, CXCL12, CXCR4, CCL7, CCL2, IFNG
22ccl345 299.6IL13, IL8, IFNG, CCL2, CCL7, CXCR4
23polysaccharide458.6CXCR4, FGF2, IL13, CCL2, CXCL12, TGFB1
24tgf beta1458.6TGFB1, IL13, TNC, CCL2, AGTR1, FGF2
25hyaluronic acid45 249.5FGF2, TNC, CXCL12, IL8, IL13, TGFB1
26matrigel458.5TNC, IL8, CXCR4, CXCL12, TGFB1, FGF2
27oxygen45 249.5AGTR1, IL8, CCL2, CCL7, CXCR4, CXCL12
28heparin45 29 24 1111.4CXCL12, IL8, SOD3, TNC, FGF2, IL13
29genistein45 29 61 3 24 1113.3CXCL12, CCL7, IL8, FGF2, AGTR1, IFNG
30pd 98,059458.2CCL2, IL8, CXCR4, CXCL12, TGFB1, IL13
31phosphatidylinositol458.2FGF2, AGTR1, IL13, CCL2, TNC, CXCR4
32histamine45 29 2410.1CCL2, IFNG, CCL7, IL13, IL8, TGFB1
33thymidine45 249.1COL3A1, TGFB1, CXCL12, IFNG, IL13, COL1A1
34nitric oxide45 24 1110.1AGTR1, IL13, CXCR4, CCL2, SERPINH1, SOD3
35arginine458.1SOD3, CXCL12, CXCR4, SFTPC, CCL2, IL13
36cysteine458.0SFTPC, TNC, SOD3, IFNG, IL8, COL1A1
37alanine458.0AGTR1, COL1A1, IL13, SOD3, TGFB1, CXCR4
38estrogen457.9AGTR1, COL1A1, IL13, CXCR4, TGFB1, CXCL12
39ly294002457.9CCL2, IL13, IL8, CXCR4, CXCL12, TGFB1
40rantes457.9TGFB1, IL13, IL8, CCL2, CCL7, CXCR4
41oligonucleotide457.8TNC, TGFB1, COL1A1, SERPINH1, CLDN5, CXCR4
42retinoic acid45 248.8SFTPC, TNC, TGFB1, CXCR4, IFNG, COL1A1
43cyclosporin a45 29 619.6CXCR4, SERPINH1, TGFB1, IL8, IL13, COL3A1
44sb 20358045 618.4TGFB1, CXCR4, CCL2, IFNG, AGTR1, IL8
45pge2457.4CXCR4, COL1A1, IL13, IL8, CCL2, TGFB1
46actinomycin d456.7IFNG, CXCL12, TNC, SFTPC, TGFB1, CCL2
47cycloheximide456.7CXCL12, CXCR4, TNC, TGFB1, CCL2, IFNG
48serine456.6TNC, TGFB1, SERPINH1, CXCL12, CXCR4, CCL7
49dexamethasone45 51 29 119.4CCL2, TGFB1, TNC, SFTPC, IFNG, COL1A1
50vegf456.1SFTPC, TNC, TGFB1, SERPINH1, IL8, SOD3

GO Terms for genes affiliated with Usual Interstitial Pneumonia

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16Gene Ontology
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Cellular components related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum lumenGO:0057889.7SERPINH1, COL1A1, COL3A1
2extracellular matrixGO:0310129.3SOD3, COL1A1, COL3A1, TNC
3external side of plasma membraneGO:0098978.9IFNG, CXCR4, CXCL12, IL13
4extracellular spaceGO:0056155.9CCL2, FGF2, COL1A1, IL13, IL8, IFNG
5extracellular regionGO:0055765.7FGF2, TNC, COL3A1, COL1A1, IL13, IL8

Biological processes related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 47)
idNameGO IDScoreTop Affiliating Genes
1ameboidal cell migrationGO:00166710.3CXCR4, CXCL12
2collagen biosynthetic processGO:03296410.3SERPINH1, COL1A1
3T cell proliferationGO:04209810.2CXCL12, CXCR4
4neutrophil activationGO:04211910.1IL8, CXCR4
5cellular response to cytokine stimulusGO:07134510.1IL13, CXCR4
6monocyte chemotaxisGO:00254810.1CCL7, CCL2
7collagen fibril organizationGO:03019910.1COL3A1, COL1A1, SERPINH1
8motor neuron axon guidanceGO:00804510.1CXCR4, CXCL12
9induction of positive chemotaxisGO:05093010.1IL8, CXCL12
10cellular response to mechanical stimulusGO:07126010.0SFTPC, IL13, COL1A1
11chemokine-mediated signaling pathwayGO:07009810.0CCL2, CXCR4, CXCL12
12negative regulation of immune responseGO:05077710.0TGFB1, COL3A1
13wound healingGO:0420609.9TNC, COL3A1, FGF2
14response to ethanolGO:0454719.9IL13, CCL2, TNC
15positive regulation of cellular protein metabolic processGO:0322709.9TGFB1, AGTR1
16calcium-mediated signalingGO:0197229.8AGTR1, IL8, CXCR4
17positive regulation of endothelial cell proliferationGO:0019389.8FGF2, CCL2, CXCL12
18cellular response to fibroblast growth factor stimulusGO:0443449.8CCL2, IL8
19response to radiationGO:0093149.8COL3A1, CXCL12, TGFB1
20negative regulation of blood vessel endothelial cell migrationGO:0435379.8TGFB1, FGF2
21germ cell migrationGO:0083549.8TGFB1, CXCL12, CXCR4
22hyaluronan catabolic processGO:0302149.8TGFB1, FGF2
23response to mechanical stimulusGO:0096129.7COL3A1, CCL2, CXCL12, TNC
24response to virusGO:0096159.7CXCL12, CXCR4, IFNG
25positive regulation of blood vessel endothelial cell migrationGO:0435369.7TGFB1, FGF2
26organ regenerationGO:0311009.6TGFB1, CXCL12, CCL2
27immune responseGO:0069559.6IL13, IL8, CCL7, CXCL12
28digestive tract developmentGO:0485659.6COL3A1, TGFB1
29positive regulation of cell migrationGO:0303359.6TGFB1, CCL7, COL1A1
30cellular component movementGO:0069289.6IFNG, IL8, IL13
31positive regulation of protein secretionGO:0507149.6IL13, TGFB1
32agingGO:0075689.6COL3A1, CCL2, TGFB1
33neutrophil chemotaxisGO:0305939.5CCL2, IFNG, IL8
34transforming growth factor beta receptor signaling pathwayGO:0071799.5COL3A1, CCL2, TGFB1
35cellular response to lipopolysaccharideGO:0712229.5IL8, IFNG, CCL2
36endoplasmic reticulum unfolded protein responseGO:0309689.5CCL2, IFNG, IL8
37cellular calcium ion homeostasisGO:0068749.5CCL2, CCL7, CXCL12, TGFB1
38positive regulation of epithelial to mesenchymal transitionGO:0107189.4COL1A1, TGFB1
39protein import into nucleus, translocationGO:0000609.4TGFB1, IFNG
40G-protein coupled receptor signaling pathwayGO:0071869.2CXCL12, CXCR4, CCL2, IL8, AGTR1
41chemotaxisGO:0069359.2FGF2, IL8, CCL2, CCL7, CXCL12
42response to hypoxiaGO:0016669.2TGFB1, SOD3, CXCL12, CXCR4, CCL2
43positive regulation of phosphatidylinositol 3-kinase activityGO:0435529.1FGF2, TGFB1
44cell cycle arrestGO:0070509.1IL8, IFNG, TGFB1
45signal transductionGO:0071658.9FGF2, IL13, IL8, CCL2, CCL7, CXCL12
46extracellular matrix organizationGO:0301988.8TNC, TGFB1, SERPINH1, COL1A1, COL3A1, FGF2
47inflammatory responseGO:0069548.7TGFB1, CXCR4, CCL7, CCL2, IL8, IL13

Molecular functions related to Usual Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1CCR2 chemokine receptor bindingGO:03172710.0CCL2, CCL7
2platelet-derived growth factor bindingGO:0484079.8COL1A1, COL3A1
3heparin bindingGO:0082019.4SOD3, CCL7, CCL2, FGF2
4chemokine activityGO:0080099.3IL8, CCL2, CCL7, CXCL12
5cytokine activityGO:0051259.3FGF2, IL13, IFNG
6growth factor activityGO:0080838.9FGF2, CXCL12, TGFB1
7protein bindingGO:0055156.6SFTPC, TGFB1, SOD3, AKR1B10, CXCR4, IL8

Products for genes affiliated with Usual Interstitial Pneumonia

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Sources for Usual Interstitial Pneumonia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet