MCID: UTR031
MIFTS: 19

Uterine Benign Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Uterine Benign Neoplasm

MalaCards integrated aliases for Uterine Benign Neoplasm:

Name: Uterine Benign Neoplasm 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:0060095

Summaries for Uterine Benign Neoplasm

MalaCards based summary : Uterine Benign Neoplasm is related to leiomyoma, uterine and bizarre leiomyoma. An important gene associated with Uterine Benign Neoplasm is HPSE2 (Heparanase 2 (Inactive)), and among its related pathways/superpathways is Thyroid hormone signaling pathway. Related phenotypes are growth/size/body region and mortality/aging

Related Diseases for Uterine Benign Neoplasm

Diseases related to Uterine Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 leiomyoma, uterine 30.3 ESR1 FH GNRH1 HMGA2 HPSE2 PGR
2 bizarre leiomyoma 10.6 MED12 PGR
3 vulvar syringoma 10.5 ESR1 PGR
4 vestibular gland benign neoplasm 10.5 ESR1 PGR
5 lung leiomyoma 10.5 ESR1 PGR
6 bartholin's gland adenoma 10.5 ESR1 PGR
7 glassy cell carcinoma of the cervix 10.5 ESR1 PGR
8 vulvar benign neoplasm 10.5 ESR1 PGR
9 trigonitis 10.5 ESR1 PGR
10 vulvar leiomyoma 10.5 ESR1 PGR
11 breast medullary carcinoma 10.5 ESR1 PGR
12 breast scirrhous carcinoma 10.5 ESR1 PGR
13 progesterone resistance 10.5 ESR1 PGR
14 progesterone-receptor positive breast cancer 10.5 ESR1 PGR
15 cribriform carcinoma 10.5 ESR1 PGR
16 oncocytic breast carcinoma 10.5 ESR1 PGR
17 bartholin's gland benign neoplasm 10.5 ESR1 PGR
18 endometrial squamous cell carcinoma 10.5 ESR1 PGR
19 gastric signet ring cell adenocarcinoma 10.5 ESR1 PGR
20 endometrial mucinous adenocarcinoma 10.5 ESR1 PGR
21 adenoid basal cell carcinoma 10.5 ESR1 PGR
22 deep angioma 10.5 ESR1 PGR
23 apocrine adenocarcinoma 10.5 ESR1 PGR
24 gender identity disorder 10.5 ESR1 PGR
25 cervical carcinosarcoma 10.5 ESR1 PGR
26 synchronous bilateral breast carcinoma 10.5 ESR1 PGR
27 breast adenoid cystic carcinoma 10.5 ESR1 PGR
28 intramuscular hemangioma 10.4 ESR1 PGR
29 estrogen excess 10.4 ESR1 PGR
30 glycogen-rich clear cell breast carcinoma 10.4 ESR1 PGR
31 mammographic density 10.4 ESR1 PGR
32 retinitis pigmentosa 47 10.4 ESR1 PGR
33 adenomyosis 10.4 ESR1 PGR
34 retinitis pigmentosa 20 10.4 ESR1 PGR
35 luminal breast carcinoma 10.4 ESR1 PGR
36 breast benign neoplasm 10.4 ESR1 MED12 PGR
37 thoracic benign neoplasm 10.4 ESR1 MED12 PGR
38 adenosarcoma 10.4 ESR1 PGR
39 cervical clear cell adenocarcinoma 10.4 ESR1 PGR
40 smooth muscle tumor 10.4 ESR1 HMGA2 PGR
41 endometriosis of uterus 10.4 GNRH1 HPSE2
42 multilocular clear cell renal cell carcinoma 10.4 TGFB3 TSC2
43 perivascular epithelioid cell tumor 10.3 PGR TSC2
44 uterine corpus cancer 10.3 ESR1 PGR
45 hereditary renal cell carcinoma 10.3 FH TSC2
46 leiomyosarcoma 10.3 FH MED12 PGR
47 endometriosis of ovary 10.3 ESR1 PGR
48 juvenile nasopharyngeal angiofibroma 10.3 ESR1 PGR TGFB3
49 inflammatory breast carcinoma 10.3 ESR1 PGR
50 pleomorphic lipoma 10.3 HMGA2 PGR

Graphical network of the top 20 diseases related to Uterine Benign Neoplasm:



Diseases related to Uterine Benign Neoplasm

Symptoms & Phenotypes for Uterine Benign Neoplasm

MGI Mouse Phenotypes related to Uterine Benign Neoplasm:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.85 VCAN CCDC57 ESR1 GNRH1 HPSE2 MED12
2 mortality/aging MP:0010768 9.7 VCAN ESR1 FH HPSE2 MED12 PGR
3 normal MP:0002873 9.17 TSC2 VCAN ESR1 GNRH1 MED12 PGR

Drugs & Therapeutics for Uterine Benign Neoplasm

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 High-intensity Focused Ultrasound in Treatment of Uterine Fibroid Active, not recruiting NCT02954744

Search NIH Clinical Center for Uterine Benign Neoplasm

Genetic Tests for Uterine Benign Neoplasm

Anatomical Context for Uterine Benign Neoplasm

Publications for Uterine Benign Neoplasm

Variations for Uterine Benign Neoplasm

Expression for Uterine Benign Neoplasm

Search GEO for disease gene expression data for Uterine Benign Neoplasm.

Pathways for Uterine Benign Neoplasm

Pathways related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.86 ESR1 MED12 TSC2

GO Terms for Uterine Benign Neoplasm

Biological processes related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular steroid hormone receptor signaling pathway GO:0030518 8.96 ESR1 MED12
2 embryonic neurocranium morphogenesis GO:0048702 8.62 MED12 TGFB3

Molecular functions related to Uterine Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Uterine Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....