MCID: UTR054
MIFTS: 20

Uterine Hypoplasia malady

Categories: Reproductive diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Uterine Hypoplasia

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Sources:
52Orphanet, 29ICD10 via Orphanet, 67UMLS via Orphanet
See all MalaCards sources

Summaries for Uterine Hypoplasia

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MalaCards based summary: Uterine Hypoplasia is related to ovarian dysgenesis 4 and ovarian dysgenesis 3. An important gene associated with Uterine Hypoplasia is BMP15 (Bone Morphogenetic Protein 15). Affiliated tissues include cervix, uterus and heart, and related mouse phenotypes are endocrine/exocrine gland and reproductive system.

Related Diseases for Uterine Hypoplasia

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Diseases related to Uterine Hypoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1ovarian dysgenesis 49.9
2ovarian dysgenesis 39.9
3ovarian dysgenesis 29.9
4mixed gonadal dysgenesis9.7BMP15, PSMC3IP
5progesterone resistance9.7
648,xxxy syndrome9.6BMP15, PSMC3IP
7adrenoleukodystrophy9.1BMP15, MCM9
8agenesis and aplasia of uterine body8.9BMP15, MCM9, PSMC3IP

Graphical network of diseases related to Uterine Hypoplasia:



Diseases related to uterine hypoplasia

Symptoms for Uterine Hypoplasia

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Drugs & Therapeutics for Uterine Hypoplasia

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Drugs for Uterine Hypoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1vitamin d1607
2
ErgocalciferolNutraceutical121150-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2

Interventional clinical trials:

idNameStatusNCT IDPhase
1Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart SyndromeRecruitingNCT01736956Phase 1, Phase 2
2Vitamin D Deficiency and Pregnancy Rates in Women Undergoing Frozen Embryo TransferCompletedNCT01985672
3Vitamin D Deficiency and Ovarian Reserve Among Infertile PatientsCompletedNCT01999608
4Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in PicardieCompletedNCT02805491

Search NIH Clinical Center for Uterine Hypoplasia

Genetic Tests for Uterine Hypoplasia

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Anatomical Context for Uterine Hypoplasia

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MalaCards organs/tissues related to Uterine Hypoplasia:

34
Cervix, Uterus, Heart, Bone

Animal Models for Uterine Hypoplasia or affiliated genes

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MGI Mouse Phenotypes related to Uterine Hypoplasia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5BMP15, MCM9, PSMC3IP
2MP:00053898.4BMP15, MCM9, PSMC3IP

Publications for Uterine Hypoplasia

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Articles related to Uterine Hypoplasia:

idTitleAuthorsYear
1
Subfertility, uterine hypoplasia, and partial progesterone resistance in mice lacking the Kruppel-like factor 9/basic transcription element-binding protein-1 (Bteb1) gene. (15117941)
2004
2
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. (9241280)
1997
3
Case of the day. 7. Diagnosis: Turner's syndrome with uterine hypoplasia. (7933009)
1994
4
Depot estrogen as a monthly contraceptive in nulliparous women with mild uterine hypoplasia. (5008627)
1972
5
Treatment of uterine hypoplasia by estrogens. (14019915)
1963
6
Primary endometrial aplasia. Congenitial absence of the endometrium without associated endocrine dysfunction or uterine hypoplasia. (13688829)
1961
7
The treatment of uterine hypoplasia by provoking pseudopregnancy with new progestin preparations. (13770451)
1961
8
A preliminary series of cases of uterine hypoplasia treated by local injection of an oestrogenic emulsion. (14368390)
1955

Variations for Uterine Hypoplasia

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Expression for genes affiliated with Uterine Hypoplasia

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Search GEO for disease gene expression data for Uterine Hypoplasia.

Pathways for genes affiliated with Uterine Hypoplasia

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GO Terms for genes affiliated with Uterine Hypoplasia

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Biological processes related to Uterine Hypoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1female gamete generationGO:00072929.0BMP15, MCM9

Sources for Uterine Hypoplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet