MCID: UTR020
MIFTS: 35

Uterine Inversion malady

Category: Reproductive diseases

Aliases & Classifications for Uterine Inversion

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Aliases & Descriptions for Uterine Inversion:

Name: Uterine Inversion 11 39 13 68
 
Inversion of Uterus During Delivery 68

Classifications:



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Disease Ontology11 DOID:997
ICD1030 N85.5
ICD9CM32 665.2
MeSH39 D019687

Summaries for Uterine Inversion

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Wikipedia:71 Uterine inversion is a potentially fatal childbirth complication with a maternal survival rate of about... more...

MalaCards based summary: Uterine Inversion, also known as inversion of uterus during delivery, is related to mucoepidermoid thyroid carcinoma and iritis. An important gene associated with Uterine Inversion is FEZF1 (FEZ Family Zinc Finger 1), and among its related pathways are Differentiation Pathway and Cardiac Progenitor Differentiation. Affiliated tissues include uterus, placenta and cervix, and related mouse phenotypes are taste/olfaction and craniofacial.

Related Diseases for Uterine Inversion

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Graphical network of the top 20 diseases related to Uterine Inversion:



Diseases related to uterine inversion

Symptoms & Phenotypes for Uterine Inversion

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MGI Mouse Phenotypes related to Uterine Inversion according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.4CSF1R, FEZF1, FEZF2
2MP:00053829.3CSF1R, F7, FEZF1, FEZF2, KIT
3MP:00030128.8CSF1R, F7, KCNJ11, KIT, MIXL1
4MP:00053787.7CSF1R, F7, FEZF1, FEZF2, KCNJ11, KIT
5MP:00107686.8CSF1R, F7, FEZF1, FEZF2, KCNJ11, KIT

Drugs & Therapeutics for Uterine Inversion

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Drugs for Uterine Inversion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Oxytocinapproved, vet_approved43950-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
 
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
2Kaolinapproved51332-58-7
3Pharmaceutical Solutions8192
4Oxytocics707
5CitrateNutraceutical1160
6
Citric Acidnutraceutical, vet_approved116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid

Interventional clinical trials:

idNameStatusNCT IDPhase
1Controlled Cord Traction During Third Stage of LaborCompletedNCT00781066Phase 3
2Prevention of Post-partum HaemorrhageCompletedNCT01044082
3In-vitro Study to Assess the Coagulation Effects of Exogenous Oxytocin Using Thromboelastography.CompletedNCT00788255
4The Cervix as a Natural Tamponade in Postpartum Hemorrhage Caused by Placenta Previa and Placenta Previa AccretaRecruitingNCT02590484
5Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168

Search NIH Clinical Center for Uterine Inversion


Cochrane evidence based reviews: uterine inversion

Genetic Tests for Uterine Inversion

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Anatomical Context for Uterine Inversion

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MalaCards organs/tissues related to Uterine Inversion:

36
Uterus, Placenta, Cervix, Ovary

Publications for Uterine Inversion

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Articles related to Uterine Inversion:

(show top 50)    (show all 220)
idTitleAuthorsYear
1
Successful use of a Bakri Tamponade Balloon in the treatment of puerperal uterine inversion during caesarean section. (27118473)
2016
2
Chronic Uterine Inversion Presenting as a Painless Vaginal Mass at 6 Months Post Partum: A Case Report. (27437313)
2016
3
Upside-Down and Inside-Out Signs in Uterine Inversion. (27298665)
2016
4
Color Doppler examination for the diagnosis of subacute puerperal uterine inversion. (27245667)
2016
5
Acute complete uterine inversion after controlled cord traction of placenta following vaginal delivery: a case report. (27386133)
2016
6
Puerperal uterine inversion managed by the uterine balloon tamponade. (26977239)
2015
7
Chronic total uterine inversion in an adolescent. (26576285)
2015
8
The Importance of the Monitoring of Resuscitation with Blood Transfusion for Uterine Inversion in Obstetrical Hemorrhage. (26491450)
2015
9
Intrauterine tamponade balloon use in the treatment of uterine inversion. (25564634)
2015
10
Uterine inversion after an unskilled delivery - still a concern for maternal mortality: A case report and discussion of the related medico-legal issues. (26232213)
2015
11
Uterus Preserving Reposition of Non-Puerperal Uterine Inversion under Laparoscope: A Case Report and Literature Review. (25634558)
2015
12
Chronic Total Uterine Inversion in a Young Adult Patient. (26494120)
2015
13
Successful reduction of acute puerperal uterine inversion with the use of a bakri postpartum balloon. (25954560)
2015
14
Uterine Balloon Tamponade Device and Cervical Cerclage to Correct Partial Uterine Inversion during Puerperium; Case Report. (25633203)
2015
15
Magnetic Resonance Imaging of Non-Puerperal Complete Uterine Inversion. (26715983)
2015
16
Non-puerperal uterine inversion in a patient with intracranial sigmoid sinus thrombosis and facial palsy. (25969481)
2015
17
Laparoscopic View of a Case of Incomplete Uterine Inversion After Vaginal Delivery. (27679099)
2015
18
Pulse contour analysis guided management of a case of puerperal uterine inversion and hemorrhagic shock - 'Giving what it takes'. (26265875)
2015
19
Sonographic diagnosis of complete uterine inversion: an unusual case. (26054129)
2015
20
Cardiac arrest following acute puerperal uterine inversion. (25694631)
2015
21
Non-puerperal uterine inversion in a young woman: a case report. (27830135)
2015
22
Chronic non puerperal uterine inversion secondary to sub-mucosal fibroid. (25272552)
2014
23
Uterine inversion after controlled cord traction during caesarean section: a case report. (25134305)
2014
24
Sonographic and MR features of puerperal uterine inversion. (24619161)
2014
25
Total and acute uterine inversion after delivery: a case report. (25326075)
2014
26
Immature uterine teratoma associated with uterine inversion. (25276328)
2014
27
Complete chronic uterine inversion with eventration of the vagina. (24767659)
2014
28
Kissing of Ovaries: Laparoscopic View of Uterine Inversion After Vaginal Delivery With Postpartum Hemorrhage. (25433278)
2014
29
Postpartum prolapsed leiomyoma with uterine inversion managed by vaginal hysterectomy. (25379314)
2014
30
Fatal postpartum air embolism due to uterine inversion and atonic hemorrhage. (23370575)
2014
31
A Rare Case of Non-puerperal Acute Uterine Inversion. (25368463)
2014
32
Acute uterine inversion: a simple modification of hydrostatic method of treatment. (24761250)
2014
33
Totally inverted cervix due to a huge prolapsed cervical myoma simulating chronic non-puerperal uterine inversion. (24997386)
2014
34
Non puerperal uterine inversion in a young female- a case report. (25386493)
2014
35
Combination of an intrauterine balloon and the "holding the cervix" technique for hemostasis of postpartum hemorrhage and for prophylaxis of acute recurrent uterine inversion. (24127992)
2013
36
Holding the cervix" technique: prophylaxis for acute recurrent uterine inversion. (23400358)
2013
37
Acute puerperal uterine inversion. (24356804)
2013
38
Complete acute uterine inversion. (24570794)
2013
39
Uterine leiomyoma associated non-puerperal uterine inversion misdiagnosed as advanced cervical cancer: A case report. (24091076)
2013
40
Sonographic findings in acute uterine inversion. (23339051)
2013
41
Non-invasive management of acute recurrent puerperal uterine inversion with Bakri postpartum balloon. (23974277)
2013
42
A case of acute on chronic uterine inversion with fibroid polyp. (24392411)
2013
43
Puerperal uterine inversion in the Netherlands: a nationwide cohort study. (22881867)
2013
44
MY (Matsubara-Yano) uterine compression suture to prevent acute recurrence of uterine inversion. (22881712)
2013
45
Non-puerperal uterine inversion caused by malignant mixed mullerian sarcoma. (24334469)
2013
46
Vaginal mass: myoma or uterine inversion or both? (23827689)
2013
47
Ultrasound diagnosis of complete uterine inversion in a nulliparous woman. (22122794)
2012
48
Uterine compression suture for acute recurrence of puerperal uterine inversion: Hayman suture? (22691274)
2012
49
Uterine inversion in association with uterine sarcoma: a case report with MRI findings and review of the literature. (22377482)
2012
50
Complete uterine inversion in a patient with endometrial cancer. (22742476)
2012

Variations for Uterine Inversion

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Expression for genes affiliated with Uterine Inversion

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Search GEO for disease gene expression data for Uterine Inversion.

Pathways for genes affiliated with Uterine Inversion

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Pathways related to Uterine Inversion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6CSF1R, KIT
29.4KIT, MIXL1

GO Terms for genes affiliated with Uterine Inversion

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Biological processes related to Uterine Inversion according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1forebrain anterior/posterior pattern specificationGO:002179710.5FEZF1, FEZF2
2forebrain developmentGO:003090010.5FEZF1, FEZF2
3olfactory bulb developmentGO:002177210.4CSF1R, FEZF1
4positive regulation of tyrosine phosphorylation of STAT proteinGO:004253110.1CSF1R, KIT
5positive regulation of tyrosine phosphorylation of Stat3 proteinGO:004251710.1CSF1R, KIT
6axon guidanceGO:000741110.1CSF1R, FEZF1, FEZF2
7digestive tract developmentGO:004856510.1KIT, MIXL1
8telencephalon developmentGO:00215379.8FEZF1, FEZF2
9positive regulation of cell migrationGO:00303359.8CSF1R, F7, KIT
10hemopoiesisGO:00300979.7CSF1R, KIT, MIXL1
11response to estradiolGO:00323559.4F7, KCNJ11, OXT

Molecular functions related to Uterine Inversion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine bindingGO:001995510.2CSF1R, KIT
2RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009789.8FEZF1, FEZF2, MIXL1
3transmembrane receptor protein tyrosine kinase activityGO:00047149.6CSF1R, KIT

Sources for Uterine Inversion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet