MCID: VGN017
MIFTS: 36

Vaginal Cancer malady

Cancer, Reproductive categories

Summaries for Vaginal Cancer

Sources:
34MedlinePlus, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Vaginal cancer is a rare type of cancer. it is more common in women 60 and older. you are also more likely to get it if you have had a human papillomavirus (hpv) infection or if your mother took diethylstilbestrol (des) when she was pregnant. doctors prescribed des in the 1950's to prevent miscarriages. you are also at higher risk if you have had abnormal cells in the vagina, cervix, or uterus. it often doesn't have early symptoms. however, see your doctor if you notice bleeding that is not your period a vaginal lump pelvic pain a pap test can find abnormal cells that may be cancer. vaginal cancer can often be cured in its early stages. treatment might include surgery, radiation therapy, and chemotherapy. nih: national cancer institute

MalaCards: Vaginal Cancer, also known as vaginal malignant epithelial tumor, is related to vulva cancer and vaginal disease. An important gene associated with Vaginal Cancer is SLC10A2 (solute carrier family 10 (sodium/bile acid cotransporter), member 2). The compound squalene have been mentioned in the context of this disorder. Affiliated tissues include liver, lymph node and uterus.

Wikipedia:64 Vaginal cancer is any type of cancer that forms in the tissues of the vagina. Primary vaginal cancer is... more...

Aliases & Classifications for Vaginal Cancer

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 49Orphanet, 34MedlinePlus, 61UMLS, 40NCIt, 57SNOMED-CT, 27ICD9CM, 35MeSH, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Reproductive


Aliases & Descriptions:

vaginal cancer 8 43 10 34
vaginal malignant epithelial tumor 49
malignant neoplasm of vagina nos 8
malignant neoplasm of vagina 8
malignant vaginal neoplasm 61
malignant tumor of vagina 8
malignant vaginal tumor 8
neoplasm of vagina 8
vaginal neoplasms 61
vaginal carcinoma 49
vagina neoplasm 8
vaginal tumor 8


External Ids:

Disease Ontology8 DOID:119
NCIt40 C7410
ICD9CM27 184.0
MeSH35 D014625
ICD10 via Orphanet26 C52
SNOMED-CT via Orphanet58 254893005
UMLS via Orphanet62 C0262659
ICD1025 C52

Related Diseases for Vaginal Cancer

Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Vaginal Cancer:



Diseases related to vaginal cancer

Clinical Features for Vaginal Cancer

Drugs & Therapeutics for Vaginal Cancer

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Vaginal Cancer

Drug clinical trials:

Search ClinicalTrials for Vaginal Cancer

Search NIH Clinical Center for Vaginal Cancer

Search CenterWatch for Vaginal Cancer

Genetic Tests for Vaginal Cancer

Anatomical Context for Vaginal Cancer

Sources:
33MalaCards
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MalaCards organs/tissues related to Vaginal Cancer:

33
Liver, Lymph node, Uterus, Colon, Thyroid, Breast, Prostate, Cervix, T cells, Appendix

Animal Models for Vaginal Cancer or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Vaginal Cancer

Sources:
51PubMed
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Articles related to Vaginal Cancer:

(show top 50)    (show all 110)
idTitleAuthorsYear
1
An Association Between Trichomonas vaginalis and High-Risk Human Papillomavirus in Rural Tanzanian Women Undergoing Cervical Cancer Screening. (24417784)
2014
2
HDR brachytherapy for the reirradiation of cervical and vaginal cancer: Analysis of efficacy and dosage delivered to organs at risk. (24161366)
2014
3
Effect of ageing on cervical or vaginal cancer in Swedish women previously treated for cervical intraepithelial neoplasia grade 3: population based cohort study of long term incidence and mortality. (24423603)
2014
4
Surveillance for recurrent cancers and vaginal epithelial lesions in patients with invasive cervical cancer after hysterectomy: are vaginal cytology and high-risk human papillomavirus testing useful? (24124151)
2013
5
Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer. (24085528)
2013
6
Self-collecting a cervico-vaginal specimen for cervical cancer screening: An exploratory study of acceptability among medically underserved women in rural Appalachia. (24125753)
2013
7
Comparisons of vaginal and abdominal radical trachelectomy for early-stage cervical cancer: preliminary results of a multi-center research in China. (24169350)
2013
8
Sexual Functioning and Vaginal Changes after Radical Vaginal Trachelectomy in Early Stage Cervical Cancer Patients: A Longitudinal Study. (24286464)
2013
9
Urethral dosimetry and toxicity with high-dose-rate interstitial brachytherapy for vaginal cancer. (23453679)
2013
10
No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses. (22470540)
2012
11
Treatment of locally advanced vaginal cancer with radiochemotherapy and magnetic resonance image-guided adaptive brachytherapy: dose-volume parameters and first clinical results. (21868174)
2012
12
American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer. (22265440)
2012
13
Definitive radiotherapy for treatment of primary vaginal cancer: effectiveness and prognostic factors. (22367326)
2012
14
Therapeutic Mechanisms of Treatment in Cervical and Vaginal Cancer. (22943045)
2012
15
The prognostic role of human papillomavirus in patients with vaginal cancer. (21666483)
2011
16
Cervical and vaginal cancer in a woman with chronic graft-versus-host disease. (21669422)
2011
17
Fibula metastasis as the presenting feature of vaginal cancer. (21446341)
2011
18
Factors affecting risk of mortality in women with vaginal cancer. (19384118)
2009
19
Descriptive epidemiology of vaginal cancer incidence and survival by race, ethnicity, and age in the United States. (18980291)
2008
20
Twenty-year review of radiotherapy for vaginal cancer: an institutional experience. (18722657)
2008
21
Hyperthermia to improve results in vaginal cancer. (18295920)
2008
22
Primary vaginal cancer treated with concurrent chemoradiation using Cis-platinum. (17512130)
2007
23
Cervical Cancer Screening for the Reluctant - HPV Testing of Air-Dried Vaginal Discharge. (23675011)
2006
24
Management of a case of primary vaginal cancer with irreducible massive uterine prolapse--a case report. (17139994)
2006
25
How innocent is the vaginal pessary? Two cases of vaginal cancer associated with pessary use. (17130056)
2006
26
Low-dose warfarin does not decrease the rate of thrombosis in patients with cervix and vulvo-vaginal cancer treated with chemotherapy, radiation, and erythropoeitin. (16406065)
2006
27
Radiofrequency ablation for the treatment of hemorrhagic vaginal cancer. (16319167)
2005
28
Methemoglobinemia induced by topical vaginal sulfanilamide cream in a patient with cervical cancer: a case report. (15907987)
2005
29
Successful pregnancy after vaginal cancer treated with interferon. (15237591)
2004
30
False-positive positron emission tomographic scan and computed tomography for recurrent vaginal cancer: pitfalls of modern imaging techniques. (14766276)
2004
31
Cost-effectiveness of pap smear screening for vaginal cancer after total hysterectomy for benign disease. (17051068)
2003
32
Efficacy and toxicity of MDR versus HDR brachytherapy for primary vaginal cancer. (12098007)
2002
33
Primary invasive vaginal cancer. Report of 12 cases. (12556110)
2002
34
A population-based study of squamous cell vaginal cancer: HPV and cofactors. (11812085)
2002
35
Vaginal cancer. (12057075)
2002
36
Tamoxifen induces endometrial and vaginal cancer in rats in the absence of endometrial hyperplasia. (10753217)
2000
37
A mullerian duct remnant myoma misdiagnosed as ovarian cancer in a woman with vaginal agenesis--a case report. (10089721)
1999
38
Behaviour of vaginal epithelial maturation and sex hormone binding globulin in post-menopausal breast cancer patients during the first year of tamoxifen therapy. (9710696)
1998
39
Primary vaginal cancer. (9537981)
1998
40
High-dose-rate brachytherapy in primary stage I and II vaginal cancer. (8244177)
1993
41
Letter: 5-Fluorouracil versus immunotherapy for non-clinical vaginal cancer. (55862)
1976
42
Immunotherapy of non-clinical vaginal cancer. (53728)
1975
43
Prenatal diethylstilbestrol and vaginal cancer in offspring. (4407195)
1974
44
Efficacy of a perineal teletherapy portal in the management of vulvar and vaginal cancer. (5024569)
1972
45
Estrogen, vaginal cancer, and vaginal development. (5025001)
1972
46
Vaginal cancer after maternal treatment with synthetic estrogens. (5556578)
1971
47
Palliation of inoperable uterine and vaginal cancer by application of a caustic. (14469049)
1962
48
Primary vaginal cancer: irradiation management and end-results. (13408489)
1957
49
Use of intra-arterial nitrogen mustard therapy in the treatment of cervical and vaginal cancer. (14902967)
1952
50
An autopsy case of primary multiple tumor (remarkable diffuse adenomyomatosis uteri combined with cancer of portio vaginalis, adenoma of thyroid gland and mucocele of appendix) [Japanese text]. (14906566)
1951

Genetic Variations for Vaginal Cancer

Expression for genes affiliated with Vaginal Cancer

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vaginal Cancer

Search GEO for disease gene expression data for Vaginal Cancer.

Pathways for genes affiliated with Vaginal Cancer

Compounds for genes affiliated with Vaginal Cancer

Sources:
45Novoseek, 24HMDB
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Compounds related to Vaginal Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1squalene45 2411.0KRT13, SLC10A2

GO Terms for genes affiliated with Vaginal Cancer

Sources:
16Gene Ontology
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Biological processes related to Vaginal Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hyperoxiaGO:0550939.9EPO, NCF2

Products for genes affiliated with Vaginal Cancer

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Vaginal Cancer

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet