MCID: VGN017
MIFTS: 42

Vaginal Cancer malady

Rare diseases, Cancer diseases, Reproductive diseases categories
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Summaries for Vaginal Cancer

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MedlinePlus:33 Vaginal cancer is a rare type of cancer. it is more common in women 60 and older. you are also more likely to get it if you have had a human papillomavirus (hpv) infection or if your mother took diethylstilbestrol (des) when she was pregnant. doctors prescribed des in the 1950's to prevent miscarriages. you are also at higher risk if you have had abnormal cells in the vagina, cervix, or uterus. it often doesn't have early symptoms. however, see your doctor if you notice bleeding that is not your period a vaginal lump pelvic pain a pap test can find abnormal cells that may be cancer. vaginal cancer can often be cured in its early stages. treatment might include surgery, radiation therapy, and chemotherapy. nih: national cancer institute

MalaCards based summary: Vaginal Cancer, also known as malignant tumor of vagina, is related to vaginitis and cervicitis. An important gene associated with Vaginal Cancer is HLA-G (major histocompatibility complex, class I, G). The compounds methotrexate and urea have been mentioned in the context of this disorder. Affiliated tissues include the vagina, cervix and uterus.

Disease Ontology:8 A female reproductive system cancer that is located in the vagina.

Wikipedia:65 Vaginal cancer is any type of cancer that forms in the tissues of the vagina. Primary vaginal cancer is... more...

Aliases & Classifications for Vaginal Cancer

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 33MedlinePlus, 62UMLS, 48Orphanet, 27ICD9CM, 57SNOMED-CT, 34MeSH, 39NCIt, 26ICD10 via Orphanet, 63UMLS via Orphanet, 25ICD10
See all sources

Vaginal Cancer, Aliases & Descriptions:

Name: Vaginal Cancer 8 42 10 33
Malignant Tumor of Vagina 8 62
Neoplasm of Vagina 8 62
Vaginal Carcinoma 48 62
Vaginal Malignant Epithelial Tumor 48
Malignant Neoplasm of Vagina, Nos 62
 
Malignant Neoplasm of Vagina 8
Malignant Vaginal Neoplasm 62
Malignant Vaginal Tumor 8
Vaginal Neoplasms 62
Vagina Neoplasm 8
Vaginal Tumor 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Reproductive diseases


External Ids:

Disease Ontology8 DOID:119
ICD9CM27 184.0
MeSH34 D014625
NCIt39 C7410
ICD10 via Orphanet26 C52
UMLS via Orphanet63 C0262659
ICD1025 C52

Related Diseases for Vaginal Cancer

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Diseases in the Vaginal Cancer family:

Vaginal Benign Neoplasm

Diseases related to Vaginal Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1vaginitis10.9
2cervicitis10.5
3vaginal germ cell malignant tumor10.2
4vulvovaginal rhabdomyosarcoma10.2
5cervical intraepithelial neoplasia10.1
6acute leukemia10.0HLA-G, EPO
7papilloma10.0
8retinoblastoma10.0
9graft versus host disease10.0
10urethritis10.0
11female reproductive organ cancer10.0
12vaginal disease10.0
13chronic graft versus host disease10.0
14mayer-rokitansky-kuster-hauser syndrome10.0

Graphical network of diseases related to Vaginal Cancer:



Diseases related to vaginal cancer

Symptoms for Vaginal Cancer

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Drugs & Therapeutics for Vaginal Cancer

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Drug clinical trials:

Search ClinicalTrials for Vaginal Cancer

Search NIH Clinical Center for Vaginal Cancer

Genetic Tests for Vaginal Cancer

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Anatomical Context for Vaginal Cancer

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MalaCards organs/tissues related to Vaginal Cancer:

32
Cervix, Uterus, Testes, Lymph node, Liver

FMA organs/tissues related to Vaginal Cancer:

14
The vagina

Animal Models for Vaginal Cancer or affiliated genes

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Publications for Vaginal Cancer

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Articles related to Vaginal Cancer:

(show top 50)    (show all 96)
idTitleAuthorsYear
1
Adoption and impact of concurrent chemoradiation therapy for vaginal cancer: A National Cancer Data Base (NCDB) study. (25281493)
2014
2
HDR brachytherapy for the reirradiation of cervical and vaginal cancer: Analysis of efficacy and dosage delivered to organs at risk. (24161366)
2014
3
Vaginal cancer in a patient with complicated prolapse history: a case report. (25181382)
2014
4
Dosimetric comparison of multichannel with one single-channel vaginal cylinder for vaginal cancer treatments with high-dose-rate brachytherapy. (24080298)
2013
5
HLA-G 3'UTR polymorphisms in high grade and invasive cervico-vaginal cancer. (23228396)
2013
6
Does histologic type correlate to outcome after pelvic exenteration for cervical and vaginal cancer? (23212765)
2013
7
Treatment of locally advanced vaginal cancer with radiochemotherapy and magnetic resonance image-guided adaptive brachytherapy: dose-volume parameters and first clinical results. (21868174)
2012
8
American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer. (22265440)
2012
9
Vulvar and vaginal cancer. (22640712)
2012
10
Vaginal cancer following etoposide-containing chemotherapy for metastatic gestational trophoblastic tumour. (22296447)
2012
11
Three-dimensional image-based high-dose-rate interstitial brachytherapy for vaginal cancer. (21665553)
2012
12
The prognostic role of human papillomavirus in patients with vaginal cancer. (21666483)
2011
13
Disparities in treatment and survival between African American and White women with vaginal cancer. (21497383)
2011
14
Cervical and vaginal cancer in a woman with chronic graft-versus-host disease. (21669422)
2011
15
Advances in vulvar and vaginal cancer treatment. (20471671)
2010
16
Descriptive epidemiology of vaginal cancer incidence and survival by race, ethnicity, and age in the United States. (18980291)
2008
17
Lymphatic mapping and sentinel lymph node detection in women with vaginal cancer. (18190952)
2008
18
Twenty-year review of radiotherapy for vaginal cancer: an institutional experience. (18722657)
2008
19
Hyperthermia to improve results in vaginal cancer. (18295920)
2008
20
Management of a case of primary vaginal cancer with irreducible massive uterine prolapse--a case report. (17139994)
2006
21
How innocent is the vaginal pessary? Two cases of vaginal cancer associated with pessary use. (17130056)
2006
22
Successful pregnancy after vaginal cancer treated with interferon. (15237591)
2004
23
False-positive positron emission tomographic scan and computed tomography for recurrent vaginal cancer: pitfalls of modern imaging techniques. (14766276)
2004
24
Cost-effectiveness of pap smear screening for vaginal cancer after total hysterectomy for benign disease. (17051068)
2003
25
Efficacy and toxicity of MDR versus HDR brachytherapy for primary vaginal cancer. (12098007)
2002
26
High-dose-rate brachytherapy for vaginal cancer: learning from treatment complications. (11860533)
2002
27
Radiotherapy alone for invasive vaginal cancer: outcome with intracavitary high dose rate brachytherapy versus conventional low dose rate brachytherapy. (11264612)
2001
28
Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: a case report. (9864414)
1999
29
Primary vaginal cancer. (9537981)
1998
30
Factor analysis of medical data of patients with primary and metastatic vaginal cancer. (9439070)
1997
31
Vaginal intraepithelial neoplasia and vaginal cancer. (8784884)
1996
32
The role of brachytherapy in the treatment of stage III vaginal cancer. A report of 3 cases. (7957336)
1994
33
High-dose-rate brachytherapy in primary stage I and II vaginal cancer. (8244177)
1993
34
Interstitial radiotherapy for early stage vaginal cancer. A new method of tumor localization. (7683723)
1993
35
Vaginal cancer: the role of infectious and environmental factors. (1659200)
1991
36
Histologic disappearance of locally advanced vaginal cancer after combination chemotherapy. (1693905)
1990
37
Serum squamous cell carcinoma antigen levels in patients with invasive squamous vulvar and vaginal cancer: a preliminary report. (2722057)
1989
38
Cervical and vaginal cancer detection at a regional diethylstilbestrol (DES) screening clinic. (3390844)
1988
39
Is hysterectomy a risk factor for vaginal cancer? (3723757)
1986
40
Viruses, specula, and vaginal cancer. (2873416)
1986
41
CO2 laser for the treatment of invasive vulvar and vaginal cancer. (6408494)
1983
42
Combined therapy as an alternative to exenteration for locally advanced vulvo-vaginal cancer: rationale and results. (7059935)
1982
43
Letter: 5-Fluorouracil versus immunotherapy for non-clinical vaginal cancer. (55862)
1976
44
Stilbestrol and vaginal cancer. (4493696)
1974
45
Efficacy of a perineal teletherapy portal in the management of vulvar and vaginal cancer. (5024569)
1972
46
Vaginal cancer after maternal treatment with synthetic estrogens. (5556578)
1971
47
Relation of carcinoma in situ of the vagina to the early diagnosis of vaginal cancer: report of a case. (13749304)
1961
48
Experimental induction of uterine cervical and vaginal cancer in mice. (13629482)
1959
49
The vaginal cancer smear; a five-year follow-up study of patients who had previous negative smears. (13666899)
1959
50
Use of intra-arterial nitrogen mustard therapy in the treatment of cervical and vaginal cancer. (14902967)
1952

Variations for Vaginal Cancer

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Expression for genes affiliated with Vaginal Cancer

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Expression patterns in normal tissues for genes affiliated with Vaginal Cancer

Search GEO for disease gene expression data for Vaginal Cancer.

Pathways for genes affiliated with Vaginal Cancer

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Compounds for genes affiliated with Vaginal Cancer

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Sources:
50PharmGKB, 44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Vaginal Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1methotrexate50 44 1111.5EPO, HLA-G
2urea44 24 1111.4EPO, HLA-G
35-aza-2deoxycytidine449.2EPO, HLA-G

GO Terms for genes affiliated with Vaginal Cancer

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Biological processes related to Vaginal Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytokine-mediated signaling pathwayGO:0192219.5EIF4A3, HLA-G

Products for genes affiliated with Vaginal Cancer

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  • Antibodies
  • Proteins
  • Lysates

Sources for Vaginal Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet