MCID: VGN017
MIFTS: 40

Vaginal Cancer malady

Cancer diseases, Reproductive diseases categories

Summaries for Vaginal Cancer

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Sources:
33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Vaginal cancer is a rare type of cancer. it is more common in women 60 and older. you are also more likely to get it if you have had a human papillomavirus (hpv) infection or if your mother took diethylstilbestrol (des) when she was pregnant. doctors prescribed des in the 1950's to prevent miscarriages. you are also at higher risk if you have had abnormal cells in the vagina, cervix, or uterus. it often doesn't have early symptoms. however, see your doctor if you notice bleeding that is not your period a vaginal lump pelvic pain a pap test can find abnormal cells that may be cancer. vaginal cancer can often be cured in its early stages. treatment might include surgery, radiation therapy, and chemotherapy. nih: national cancer institute

MalaCards: Vaginal Cancer, also known as vaginal malignant epithelial tumor, is related to vaginitis and cervical cancer. An important gene associated with Vaginal Cancer is SLC10A2 (solute carrier family 10 (sodium/bile acid cotransporter), member 2). The compound squalene have been mentioned in the context of this disorder. Affiliated tissues include testes, cervix and uterus.

Wikipedia:63 Vaginal cancer is any type of cancer that forms in the tissues of the vagina. Primary vaginal cancer is... more...

Aliases & Classifications for Vaginal Cancer

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 48Orphanet, 33MedlinePlus, 60UMLS, 39NCIt, 56SNOMED-CT, 27ICD9CM, 34MeSH, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Reproductive diseases


Aliases & Descriptions:

vaginal cancer 8 42 10 33
vaginal malignant epithelial tumor 48
malignant neoplasm of vagina nos 8
malignant neoplasm of vagina 8
malignant vaginal neoplasm 60
malignant tumor of vagina 8
malignant vaginal tumor 8
neoplasm of vagina 8
vaginal neoplasms 60
vaginal carcinoma 48
vagina neoplasm 8
vaginal tumor 8


External Ids:

Disease Ontology8 DOID:119
NCIt39 C7410
ICD9CM27 184.0
MeSH34 D014625
ICD10 via Orphanet26 C52
SNOMED-CT via Orphanet57 254893005
UMLS via Orphanet61 C0262659
ICD1025 C52

Related Diseases for Vaginal Cancer

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Vaginal Cancer:



Diseases related to vaginal cancer

Clinical Features for Vaginal Cancer

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Drugs & Therapeutics for Vaginal Cancer

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Vaginal Cancer

Drug clinical trials:

Search ClinicalTrials for Vaginal Cancer

Search NIH Clinical Center for Vaginal Cancer

Search CenterWatch for Vaginal Cancer

Genetic Tests for Vaginal Cancer

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Anatomical Context for Vaginal Cancer

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Sources:
32MalaCards
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MalaCards organs/tissues related to Vaginal Cancer:

32
Testes, Cervix, Uterus, Breast, Lymph node, Colon, Liver

Animal Models for Vaginal Cancer or affiliated genes

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Publications for Vaginal Cancer

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50PubMed
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Articles related to Vaginal Cancer:

(show top 50)    (show all 107)
idTitleAuthorsYear
1
Surveillance for recurrent cancers and vaginal epithelial lesions in patients with invasive cervical cancer after hysterectomy: are vaginal cytology and high-risk human papillomavirus testing useful? (24124151)
2013
2
Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer. (24085528)
2013
3
HLA-G 3'UTR polymorphisms in high grade and invasive cervico-vaginal cancer. (23228396)
2013
4
Concurrent chemoradiation for vaginal cancer. (23762284)
2013
5
Vaginal cancer with multiple liver and pulmonary metastases that achieved long-term survival. (24396823)
2013
6
Vaginal-assisted laparoscopic radical hysterectomy (VALRH) versus laparoscopic-assisted radical vaginal hysterectomy (LARVH) in the treatment of cervical cancer: surgical results and oncologic outcome. (24362556)
2013
7
Vaginal cancer: the experience from 2 large academic centers during a 15-year period. (23609592)
2013
8
Influence of bevacizumab on vaginal cuff evisceration eight months after ovarian cancer cytoreduction surgery: A case report. (24371706)
2013
9
Treatment of locally advanced vaginal cancer with radiochemotherapy and magnetic resonance image-guided adaptive brachytherapy: dose-volume parameters and first clinical results. (21868174)
2012
10
Vulvar and vaginal cancer. (22640712)
2012
11
Vaginal cancer following etoposide-containing chemotherapy for metastatic gestational trophoblastic tumour. (22296447)
2012
12
Vaginal cancer. (21571543)
2012
13
Estimation of the optimal brachytherapy utilisation rate in the treatment of vaginal cancer and comparison with patterns of care. (22883660)
2012
14
Disparities in treatment and survival between African American and White women with vaginal cancer. (21497383)
2011
15
Primary vaginal cancer and chemoradiotherapy: a patterns-of-care analysis. (21270620)
2011
16
Epidemiology of vulvar and vaginal cancer in Germany. (21340687)
2011
17
Vaginal pH-balanced gel for the control of atrophic vaginitis among breast cancer survivors: a randomized controlled trial. (21422866)
2011
18
Early cervical cancer complicated by pyometra presenting as a pelvic cystic mass and vaginitis in a 102-year-old patient. (21668919)
2011
19
Advances in vulvar and vaginal cancer treatment. (20471671)
2010
20
Descriptive epidemiology of vaginal cancer incidence and survival by race, ethnicity, and age in the United States. (18980291)
2008
21
Hyperthermia to improve results in vaginal cancer. (18295920)
2008
22
Genital tuberculosis in a tamoxifen-treated postmenopausal woman with breast cancer and bloody vaginal discharge. (16948834)
2006
23
Vaginal cancer in a patient treated for cervical intraepithelial neoplasia (CIN 3): case report. (17290605)
2006
24
Radiofrequency ablation for the treatment of hemorrhagic vaginal cancer. (16319167)
2005
25
Radiotherapy for the treatment of primary vaginal cancer. (16260055)
2005
26
Cost-effectiveness of pap smear screening for vaginal cancer after total hysterectomy for benign disease. (17051068)
2003
27
High-dose-rate brachytherapy for vaginal cancer: learning from treatment complications. (11860533)
2002
28
Treatment failure in vaginal cancer. (11812092)
2002
29
Radiotherapy alone for invasive vaginal cancer: outcome with intracavitary high dose rate brachytherapy versus conventional low dose rate brachytherapy. (11264612)
2001
30
Lactobacilli-mediated control of vaginal cancer through specific reactive oxygen species interaction. (11461184)
2001
31
Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: a case report. (9864414)
1999
32
Primary vaginal cancer. (9537981)
1998
33
Factor analysis of medical data of patients with primary and metastatic vaginal cancer. (9439070)
1997
34
Vaginal intraepithelial neoplasia and vaginal cancer. (8784884)
1996
35
Screening for vaginal cancer. (8900096)
1996
36
The vaginal radical operation of cervical cancer. (8556579)
1995
37
High-dose-rate brachytherapy in primary stage I and II vaginal cancer. (8244177)
1993
38
Interstitial radiotherapy for early stage vaginal cancer. A new method of tumor localization. (7683723)
1993
39
Serum squamous cell carcinoma antigen levels in patients with invasive squamous vulvar and vaginal cancer: a preliminary report. (2722057)
1989
40
DNA analysis cervical and vaginal cancer cells during radiotherapy by rapid high-resolution cytometry. (3385280)
1988
41
Viruses, specula, and vaginal cancer. (2873416)
1986
42
Vaginal cancer after hysterectomy for benign disease: value of cytologic screening. (6493662)
1984
43
CO2 laser for the treatment of invasive vulvar and vaginal cancer. (6408494)
1983
44
Immunotherapy of non-clinical vaginal cancer. (53728)
1975
45
Vaginal cancer: an iatrogenic disease? (1181297)
1975
46
Vaginal cancer after maternal treatment with synthetic estrogens. (5556578)
1971
47
Practical colposcopy in early cervical and vaginal cancer. (4871716)
1967
48
Relation of carcinoma in situ of the vagina to the early diagnosis of vaginal cancer: report of a case. (13749304)
1961
49
The vaginal cancer smear; a five-year follow-up study of patients who had previous negative smears. (13666899)
1959
50
Use of intra-arterial nitrogen mustard therapy in the treatment of cervical and vaginal cancer. (14902967)
1952

Genetic Variations for Vaginal Cancer

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Expression for genes affiliated with Vaginal Cancer

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vaginal Cancer

Search GEO for disease gene expression data for Vaginal Cancer.

Pathways for genes affiliated with Vaginal Cancer

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Compounds for genes affiliated with Vaginal Cancer

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44Novoseek, 24HMDB
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Compounds related to Vaginal Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1squalene44 2411.0KRT13, SLC10A2

GO Terms for genes affiliated with Vaginal Cancer

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Sources:
16Gene Ontology
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Biological processes related to Vaginal Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hyperoxiaGO:0550939.9EPO, NCF2

Products for genes affiliated with Vaginal Cancer

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Vaginal Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet