MCID: VGN019
MIFTS: 32

Vaginal Discharge

Categories: Reproductive diseases

Aliases & Classifications for Vaginal Discharge

MalaCards integrated aliases for Vaginal Discharge:

Name: Vaginal Discharge 12 42 14

Classifications:



External Ids:

Disease Ontology 12 DOID:3767
MeSH 42 D019522
NCIt 47 C50795
UMLS 69 C0227791

Summaries for Vaginal Discharge

MalaCards based summary : Vaginal Discharge is related to vaginitis and bacterial vaginosis. An important gene associated with Vaginal Discharge is DSPP (Dentin Sialophosphoprotein). The drugs Dinoprostone and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and cervix.

Wikipedia : 72 Vaginal discharge is a mixture of liquid, cells, and bacteria that lubricates and protects the vagina.... more...

Related Diseases for Vaginal Discharge

Graphical network of the top 20 diseases related to Vaginal Discharge:



Diseases related to Vaginal Discharge

Symptoms & Phenotypes for Vaginal Discharge

Drugs & Therapeutics for Vaginal Discharge

Drugs for Vaginal Discharge (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 150)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dinoprostone Approved Phase 4,Phase 3,Phase 2 363-24-6 5280360
2
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1 443-48-1 4173
3
Clindamycin Approved, Vet_approved Phase 4,Phase 3 18323-44-9 29029
4
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
5
Clotrimazole Approved, Vet_approved Phase 4,Phase 3 23593-75-1 2812
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Desogestrel Approved Phase 4,Phase 2,Phase 3 54024-22-5 40973
8
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 54048-10-1 40976 6917715
9
Misoprostol Approved Phase 4,Phase 2,Phase 3 59122-46-2 5282381
10
Povidone Approved Phase 4,Phase 3,Phase 2 9003-39-8
11 Povidone-iodine Approved Phase 4,Phase 3,Phase 2 25655-41-8
12
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-28-2 5757
13
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
14
Ethinyl Estradiol Approved Phase 4,Phase 2,Phase 3,Phase 1 57-63-6 5991
15
Glycerol Approved, Investigational Phase 4,Phase 2 56-81-5 753
16
Loperamide Approved Phase 4,Phase 2 53179-11-6 3955
17
Mineral oil Approved, Vet_approved Phase 4,Phase 2 8042-47-5
18
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
19
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
20
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
21
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
22
Iodine Investigational Phase 4,Phase 3,Phase 2 7553-56-2 807
23 Oxytocics Phase 4,Phase 3,Phase 2
24 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
25 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1
26 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1
27 Anti-Bacterial Agents Phase 4,Phase 3
28 Clindamycin palmitate Phase 4,Phase 3
29 Clindamycin phosphate Phase 4,Phase 3
30 Neurotransmitter Agents Phase 4
31 Analgesics Phase 4,Phase 2
32 Anesthetics Phase 4
33 Narcotics Phase 4
34 Peripheral Nervous System Agents Phase 4,Phase 2
35 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
36 Hormones Phase 4,Phase 3,Phase 2,Phase 1
37 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
38 Progestins Phase 4,Phase 3,Phase 2,Phase 1
39 Central Nervous System Depressants Phase 4
40 Antibiotics, Antitubercular Phase 4
41 Antitubercular Agents Phase 4
42 Analgesics, Opioid Phase 4
43 Cholinergic Agents Phase 4
44 Cholinergic Antagonists Phase 4
45 Muscarinic Antagonists Phase 4
46 Tolterodine tartrate Phase 4 124937-52-6
47 Analgesics, Non-Narcotic Phase 4,Phase 2
48 Antipyretics Phase 4
49 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
50 Contraceptive Agents Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 124)

id Name Status NCT ID Phase Drugs
1 Efficacy of Induction of Labor on Term Using a Double Balloon Catheter Compared to Dinoprostone Vaginal-insert Unknown status NCT01720394 Phase 4 Dinoprostone
2 Safety and Tolerability of Metronidazole Gel 1.3% Completed NCT02392026 Phase 4 Metronidazole Gel
3 Double Balloon Catheter Versus Dinoprostone Vaginal Insert for Cervical Ripening. Completed NCT01170819 Phase 4 Dinoprostone 10 mg controlled-release vaginal insert
4 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4 ClinSupV3 -soft gelatin capsule;ClinSupV3ER- Extended release tablet
5 24-Hour Vaginal Dinoprostone Pessary Versus Gel for Labour Induction Completed NCT00843362 Phase 4 Dinoprostone vaginal pessary;Dinoprostone vaginal gel
6 Effectiveness of Intracavitary Manual Lymphatic Drainage Completed NCT02960841 Phase 4
7 A Study to Measure the Effect of Tolterodine Extended Release on the Thickness of the Bladder Wall in Patients With Overactive Bladder Completed NCT00137397 Phase 4 Tolterodine ER;Placebo
8 RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Operative Vaginal Reconstruction Pain Completed NCT02043704 Phase 4 IV Acetaminophen
9 Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant Completed NCT00847587 Phase 4 Etonogestrel contraceptive implant;Etonogestrel contraceptive implant
10 Tolerance of Chlorhexidine Gluconate Vaginal Cleansing Solution Recruiting NCT03305159 Phase 4 Povidone-Iodine;4% Chlorhexidine Gluconate
11 Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery Recruiting NCT02287246 Phase 4 Extended-Release liposomal bupivacaine (Exparel);Normal saline
12 Vaginal Misodel® in Comparison With Orally Administrated Misoprostol (Cytotec®) at Induction of Labour Recruiting NCT02918110 Phase 4 Misoprostol
13 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Recruiting NCT02042287 Phase 4 Metronidazole
14 Vaginal Misoprostol Before IUD Insertion in Women With Cesarean Scar Recruiting NCT03081442 Phase 4 Misoprostol
15 Balloon Catheter Versus Propess for Labour Induction Recruiting NCT03199820 Phase 4 Prostin E2 Vaginal Suppository
16 Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour Recruiting NCT02539199 Phase 4 Misoprostol, modified-release pessary;Misoprostol, per-oral tablets
17 The Vaginal Health Trial Active, not recruiting NCT02516202 Phase 4 Vagifem;Replens
18 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Active, not recruiting NCT02629510 Phase 4 Tachosil
19 Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery Active, not recruiting NCT03052816 Phase 4 Ice T;Motrin/Percocet/Dilaudid for breakthrough
20 Prolonged Treatment for Infected Abortion After Hospital Discharge. Terminated NCT00376493 Phase 4 metronidazole and doxycycline
21 NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles Terminated NCT01638767 Phase 4 Contraceptives, Oral;Contraceptive, Vaginal ring
22 A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis Unknown status NCT01089348 Phase 2, Phase 3 Lactofiltrum + Metronidazole;Metronidazole
23 Luteal Phase Progesterone in IUI and Gonadotropin Cycles Unknown status NCT01941875 Phase 3 Progesterone Effervescent Vaginal Tablets
24 Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge Completed NCT02111629 Phase 3 Fluconazole and Secnidazole
25 Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments Completed NCT00313131 Phase 3 tinidazole+fluconazole vs metronidazole+clotrimazole
26 The Value of Bacterial Loads by Real Time PCR in Predicting Recurrence of Abnormal Vaginal Flora After Oral Metronidazole Therapy Completed NCT01287728 Phase 3 Treatment BY METROMIDAZOLE
27 Efficacy and Safety of Clino-san on Vaginal Dryness of Breast Cancer Patients Completed NCT00607295 Phase 3 clino-san vaginal lubricant
28 Diabetes Mellitus and Vulvovaginal Candidiasis Completed NCT00353561 Phase 3 Boric;Fluconazole
29 A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment o Completed NCT02210689 Phase 3 clindamycin phosphate vaginal cream 2%
30 Assessment of the Efficacy of POLYGYNAX® in the Empirical Treatment of Infectious Vaginitis Completed NCT02515656 Phase 3 POLYGYNAX®;GYNODAKTARIN®;Placebo
31 Prostin and Propess in Induction of Labor Completed NCT01635439 Phase 3 Propess;Prostin E2
32 Vaginal Progesterone to Reduce the Risk of Another Preterm Birth Completed NCT00086177 Phase 3 8% progesterone vaginal gel;Placebo Vaginal Gel
33 Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy Completed NCT01796613 Phase 2, Phase 3
34 Assessment of the Transfer of Using Levonorgestrel Intrauterine System (LNG IUS) as a Contraceptive to Using it as Part of Hormone Replacement Therapy (HRT). Completed NCT00185458 Phase 3 LNG IUS
35 Trial of Trimosan Gel Effect on Pessary-associated Bacterial Vaginosis Completed NCT01471457 Phase 2, Phase 3 Trimo-San gel
36 Cervical Ripening Before Induction of Labour at Term: a Randomised Comparison of Prostin vs Propess Completed NCT00545194 Phase 3 Prostaglandin E2
37 Induction of Labor in Term Premature Rupture of Membranes: A Comparison Between Oxytocin and Dinoprostone Followed Six Hours Later by Oxytocin Completed NCT01099280 Phase 3 SYNPITAN FORT 5 IU;Propess,SYNPITAN FORT
38 An Open-label Trial Investigating the Efficacy and Safety of a Vaginal Insert in Pregnant Women at Term Recruiting NCT03067597 Phase 3 Dinoprostone
39 An RCT of a Synthetic Osmotic Cervical Dilator for Induction of Labour in Comparison to Dinoprostone Vaginal insErt Not yet recruiting NCT03001661 Phase 3 Dinoprostone
40 Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction Not yet recruiting NCT02684305 Phase 3 Administration of Propess;Intravenous oxytocin infusion
41 Repeated Doses of Misoprostol for Medical Treatment of Missed Miscarriage Suspended NCT01615224 Phase 2, Phase 3 misoprostol
42 A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections Terminated NCT00528008 Phase 3
43 Efficacy and Safety of the Association of Clotrimazole and Metronidazole in the Treatment of Vaginal Discharge From Different Etiologies. Withdrawn NCT02713139 Phase 3 Clotrimazole + Metronidazole;Metronidazole;Clotrimazole
44 Intravaginal LACTIN-V for Prevention of Recurrent Urinary Tract Infection Completed NCT00305227 Phase 2 Lactin-V;Placebo
45 Metronidazole for Pulmonary Tuberculosis (South Korea) Completed NCT00425113 Phase 2 Metronidazole
46 Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis Completed NCT01055106 Phase 2 GW05;GW05;GW05;Metronidazole
47 Tactile Electrosurgical Ablation in Cases of Dysfunctional Uterine Bleeding Completed NCT02248194 Phase 2
48 Safety and Efficacy Study of Misoprostol Vaginal Insert for Induction of Labour Completed NCT00346840 Phase 2 Misoprostol vaginal insert 25 mcg;Misoprostol vaginal insert 50 mcg;Misoprostol vaginal insert 100 mcg;Misoprostol vaginal insert 200 mcg
49 Comparison Between 25 µg Vaginal Misoprostol vs Slow Release Pessary PGE2 Completed NCT01765881 Phase 2 Misoprostol;Dinoprostone
50 A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057) Completed NCT01670656 Phase 2 Nomegestrol acetate contraceptive vaginal ring (NOMAC-CVR);Etonogestrel containing contraceptive vaginal ring (ENG-CVR);Placebo;Ibuprofen

Search NIH Clinical Center for Vaginal Discharge

Cochrane evidence based reviews: vaginal discharge

Genetic Tests for Vaginal Discharge

Anatomical Context for Vaginal Discharge

MalaCards organs/tissues related to Vaginal Discharge:

39
Skin, Testes, Cervix, Placenta, Ovary, Uterus, Kidney

Publications for Vaginal Discharge

Articles related to Vaginal Discharge:

(show top 50) (show all 325)
id Title Authors Year
1
Effects of intrauterine infusion of Escherichia coli lipopolysaccharide on uterine mRNA gene expression and peripheral polymorphonuclear leukocytes in Jersey cows diagnosed with purulent vaginal discharge. ( 28434729 )
2017
2
Application of a bacteriological on-farm test to reduce antimicrobial usage in dairy cows with purulent vaginal discharge. ( 28237589 )
2017
3
Purulent vaginal discharge in grazing dairy cows: Risk factors, reproductive performance, and prostaglandin F2I+ treatment. ( 28318582 )
2017
4
Trichomonas vaginalis is very rare among women with vaginal discharge in Podlaskie province, Poland. ( 28612378 )
2017
5
Primary chylous vaginal discharge demonstrated with noncontrast magnetic resonance lymphography. ( 28475249 )
2017
6
Cervical cytopathological changes among women with vaginal discharge attending teaching hospital. ( 28469316 )
2017
7
Effectiveness of intrauterine treatment with cephapirin in dairy cows with purulent vaginal discharge. ( 28043367 )
2017
8
Epidemiology and clinico-investigative study of organisms causing vaginal discharge. ( 28442807 )
2017
9
Effect of diagnosis and treatment of clinical endometritis based on vaginal discharge score grading system in postpartum Holstein cows. ( 28740032 )
2017
10
An Insight to How Estate Women in Sri Lanka Manage Abnormal Vaginal Discharge. ( 28451566 )
2017
11
Effects of intrauterine infusion of Escherichia coli lipopolysaccharide on uterine health, resolution of purulent vaginal discharge, and reproductive performance of lactating dairy cows. ( 28434752 )
2017
12
Genetic and functional analysis of the bovine uterine microbiota. Part II: Purulent vaginal discharge versus healthy cows. ( 28259411 )
2017
13
Syndromic management of sexually transmissible infections in resource-poor settings: a systematic review with meta-analysis of the abnormal vaginal discharge flowchart for Neisseria gonorrhoea and Chlamydia trachomatis. ( 28838352 )
2017
14
High Risk Human Papilloma Virus Genotypes in Kurdistan Region in Patients with Vaginal Discharge. ( 27509950 )
2016
15
Efficacy of syndromic management measured as symptomatic improvement in females with vaginal discharge syndrome. ( 27190409 )
2016
16
Co-infection with Bovine Herpesvirus 4 and Histophilus somni Significantly Extends the Service Period in Dairy Cattle with Purulent Vaginal Discharge. ( 26690881 )
2016
17
Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge. ( 27843660 )
2016
18
Do female patients with nonpathological vaginal discharge need the same evaluation as for Dhat syndrome in males? ( 26985107 )
2016
19
Utility of Laboratory Diagnosis for Confirmation of the Syndromic Case Management in Married Indian Women with Vaginal Discharge. ( 27833516 )
2016
20
Variables associated with vaginal discharge after ultrasound-guided percutaneous microwave ablation for adenomyosis. ( 27087631 )
2016
21
Prepubertal vaginal discharge: Vaginoscopy to rule out foreign body. ( 27976557 )
2016
22
The Performance of the Vaginal Discharge Syndromic Management in Treating Vaginal and Cervical Infection: A Systematic Review and Meta-Analysis. ( 27706174 )
2016
23
Sore throat A^ vaginal discharge A^ labial ulcer A^ Dx? ( 27474821 )
2016
24
Study to Evaluate Targeted Management and Syndromic Management in Women Presenting with Abnormal Vaginal Discharge. ( 27651658 )
2016
25
Primary care management of women with persistent vaginal discharge. ( 27861272 )
2016
26
Randomized clinical trial of intrauterine cephapirin infusion in dairy cows for the treatment of purulent vaginal discharge and cytological endometritis. ( 26210270 )
2015
27
Diagnostic Value of Vaginal Discharge, Wet Mount and Vaginal pH - An Update on the Basics of Gynecologic Infectiology. ( 26028693 )
2015
28
Determination of optimal diagnostic criteria for purulent vaginal discharge and cytological endometritis in dairy cows. ( 26210278 )
2015
29
Menstrual hygiene practices and its association with reproductive tract infections and abnormal vaginal discharge among women in India. ( 26614609 )
2015
30
A 78-Year-Old Woman with Fecaloid Vaginal Discharge. ( 26495410 )
2015
31
Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen. ( 25569004 )
2015
32
Profuse Vaginal Discharge May Equally Suggest Adenoma Malignum and Lobular Endocervical Glandular Hyperplasia (LEGH), But Same Cover, Different Story. ( 27678817 )
2015
33
Utility of microbiological profile of symptomatic vaginal discharge in rural women of reproductive age group. ( 25954668 )
2015
34
Effect of intrauterine dextrose on reproductive performance of lactating dairy cows diagnosed with purulent vaginal discharge under certified organic management. ( 25828665 )
2015
35
Chylocolporrhea or chylous vaginal discharge: diagnostic conundrum with therapeutic challenge. ( 26386963 )
2015
36
Uterine Natural Killer Cell and Human Leukocyte Antigen-G1 and Human Leukocyte Antigen-G5 Expression in Vaginal Discharge of Threatened-Abortion Women: A Case-Control Study. ( 26509178 )
2015
37
Technical note: Intraobserver, interobserver, and test-retest reliabilities of an assessment of vaginal discharge from cows with and without acute puerperal metritis. ( 26026759 )
2015
38
Chronic vaginal discharge due to vesicovaginal fistula. ( 25876713 )
2015
39
A rare case of foreign body causing recurrent vaginal discharge in prepubertal child. ( 25738041 )
2015
40
Vaginal discharge in a young woman. ( 25077397 )
2014
41
Diagnosis of acute puerperal metritis by electronic nose device analysis of vaginal discharge in dairy cows. ( 24746098 )
2014
42
A 3-year-old girl with a recent history of yellow-green vaginal discharge. ( 24605856 )
2014
43
Effects of vaginal discharge on female sexual function. ( 24119895 )
2014
44
Performance of the Affirm VP-III using residual vaginal discharge collected from the speculum to characterize vaginitis in symptomatic women. ( 24832170 )
2014
45
Evaluation of vaginal discharge with the Metricheck device and the relationship to reproductive performance in postpartum dairy cows. ( 24961582 )
2014
46
Sexually transmitted infections in women: A correlation of clinical and laboratory diagnosis in cases of vaginal discharge syndrome. ( 25506555 )
2014
47
Persistent vaginal discharge following proctocolectomy-if there is no fistula, what is it? ( 23948868 )
2014
48
Validation of vaginal discharge syndrome among pregnant women attending obstetrics clinic, in the tertiary hospital of Western India. ( 26396446 )
2014
49
Gossypiboma: a rare cause of chronic vaginal discharge after laparoscopic hysterectomy. ( 25270159 )
2014
50
Co-infections with Ureaplasma parvum, Mycoplasma hominis and Chlamydia trachomatis in a human immunodeficiency virus positive woman with vaginal discharge. ( 23867681 )
2013

Variations for Vaginal Discharge

Expression for Vaginal Discharge

Search GEO for disease gene expression data for Vaginal Discharge.

Pathways for Vaginal Discharge

GO Terms for Vaginal Discharge

Cellular components related to Vaginal Discharge according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cortical cytoskeleton GO:0030863 8.62 FLNA GYPC

Sources for Vaginal Discharge

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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