Summaries for Vaginitis

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Wikipedia:65 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards based summary: Vaginitis, also known as infective vaginitis, is related to adenocarcinoma and leiomyoma. An important gene associated with Vaginitis is SH2D1A (SH2 domain containing 1A), and among its related pathways are MNAR-PELP1 and Estrogen Receptor Interaction and Plasma membrane estrogen receptor signaling. The compounds r,r-thc and 17alpha estradiol have been mentioned in the context of this disorder. Affiliated tissues include testes, uterus and cervix, and related mouse phenotypes are digestive/alimentary and endocrine/exocrine gland.

Aliases & Classifications for Vaginitis

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Vaginitis, Aliases & Descriptions:

Name: Vaginitis 10
Infective Vaginitis 62
 
Vaginitis Nos 62


External Ids:

Disease Ontology10 DOID:2170
MeSH35 D014627
NCIt40 C26911

Related Diseases for Vaginitis

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Graphical network of the top 20 diseases related to Vaginitis:



Diseases related to vaginitis

Symptoms for Vaginitis

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Drugs & Therapeutics for Vaginitis

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Drug clinical trials:

Search ClinicalTrials for Vaginitis

Search NIH Clinical Center for Vaginitis

Genetic Tests for Vaginitis

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Anatomical Context for Vaginitis

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MalaCards organs/tissues related to Vaginitis:

33
Testes, Uterus, Cervix, Colon, Placenta, Neutrophil, Kidney, Ovary, Breast, Bone, Liver, Myeloid, T cells, Lymph node, Skin, Heart, Smooth muscle, Thyroid, Prostate, Lung, Monocytes, Pituitary

Animal Models for Vaginitis or affiliated genes

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Publications for Vaginitis

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Articles related to Vaginitis:

(show top 50)    (show all 2280)
idTitleAuthorsYear
1
Emphysematous vaginitis. (25551590)
2015
2
Intrapartum anti-disseminated intravascular coagulation therapy leading to successful vaginal delivery following intrauterine fetal death caused by placental abruption: a case report. (25532532)
2014
3
Accounting for Anovulation and Vaginal Thinning During Depot Medroxyprogesterone Acetate Use. (25217405)
2014
4
The role of physical examination in diagnosing common causes of vaginitis: a prospective study. (23019659)
2013
5
Co-infections with Ureaplasma parvum, Mycoplasma hominis and Chlamydia trachomatis in a human immunodeficiency virus positive woman with vaginal discharge. (23867681)
2013
6
Dosimetric comparison of multichannel with one single-channel vaginal cylinder for vaginal cancer treatments with high-dose-rate brachytherapy. (24080298)
2013
7
Innate immunity in the vagina (part I): estradiol inhibits HBD2 and elafin secretion by human vaginal epithelial cells. (23398087)
2013
8
Spectrum of vaginal discharge in a tertiary care setting. (24470998)
2013
9
Diverse vaginal microbiomes in reproductive-age women with vulvovaginal candidiasis. (24265786)
2013
10
Temporary endovascular balloon occlusion of the bilateral internal iliac arteries to control hemorrhage during laparoscopic-assisted vaginal hysterectomy for cervical myoma. (21658835)
2011
11
The prognostic role of human papillomavirus in patients with vaginal cancer. (21666483)
2011
12
In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models. (20805398)
2010
13
Early vaginal bleeding has no impact on markers used in first trimester aneuploidy screening. (20509154)
2010
14
Expression of occludin and zona occluden-1 and their morphologic changes in vagina mucosal cells in patients undergoing vaginal construction by using sigmoid colon]. (20003786)
2009
15
Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding. (19260253)
2009
16
Fetal acidosis from obstetric interventions during the first vaginal delivery. (19126504)
2008
17
Concurrent imperforate hymen, transverse vaginal septum, and unicornuate uterus: a case report. (17706513)
2007
18
Vaginal fibrosarcoma in a cow. (21851697)
2007
19
Analysis of vaginal recurrences in stage I endometrial adenocarcinoma. (17713101)
2007
20
Does vaginal bleeding influence first-trimester markers for Down syndrome? (17286311)
2007
21
Molecular evidence of congenital candidiasis associated with maternal candidal vaginitis. (16804443)
2006
22
Influence of exogenous reproductive hormones on specific antibody production in genital secretions after vaginal vaccination with recombinant cholera toxin B subunit in humans. (16467326)
2006
23
Cervical Cancer Screening for the Reluctant - HPV Testing of Air-Dried Vaginal Discharge. (23675011)
2006
24
Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients. (16006060)
2005
25
Information from your family doctor. Vaginitis. (15606062)
2004
26
Polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, local midtrimester cytokine response to vaginal flora, and subsequent preterm birth. (15507961)
2004
27
Vaginal misoprostol for induction of labour: a more effective agent than prostaglandin F2 alpha gel and prostaglandin E2 pessary. (14562597)
2002
28
Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans. (11705923)
2001
29
Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium. (10084314)
1999
30
Vaginal depth following reconstruction with pudendal thigh flaps in congenital vaginal atresia. (9030179)
1997
31
Long-term efficacy and safety of a disposable vaginal device (continence guard) in the treatment of female stress incontinence. (9449583)
1997
32
Vaginal stone in a male patient with true hermaphroditism. (9488939)
1997
33
Lactobacillus GG vaginal suppositories and vaginitis. (7615776)
1995
34
Depressed serum levels of human placental lactogen in first trimester vaginal bleeding. (7531935)
1995
35
Gartner's duct cyst with a single vaginal ectopic ureter and associated renal dysplasia or agenesis. (8301720)
1993
36
Split-dose metronidazole or single-dose tinidazole for the treatment of vaginal trichomoniasis. (1411848)
1992
37
Evaluation of a latex agglutination test for the identification of Candida species in vaginal discharge. (1496893)
1992
38
Vaginitis. (1956016)
1991
39
The treatment of vaginal atresia. (2028378)
1991
40
Allergic vaginitis mimicking bacterial vaginosis. (1965569)
1990
41
Prevalence of common infective agents of vaginitis. (2614050)
1989
42
Vaginal discharge and cystitis. (3399160)
1988
43
The role of benzydamine in the topical treatment of the so-called non-specific vaginitis. (3497131)
1987
44
Vaginal discharge. (3098348)
1986
45
The challenges of vaginal atresia and stenosis: Nigerian experience. (6144585)
1984
46
Double blind comparative study of tinidazole and ornidazole as a single dose treatment of vaginal trichomoniasis. (7000949)
1980
47
Single-dose treatment of vaginal trichomoniasis with tinidazole. (4617665)
1974
48
A case of pyomucocolpos due to a transverse vaginal septum]. (5106198)
1971
49
'Gathering' of tunica vaginal in the surgical cure of idiopathic hydrocele. (5651615)
1968
50
Experimental induction of uterine cervical and vaginal cancer in mice. (13629482)
1959

Variations for Vaginitis

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Expression for genes affiliated with Vaginitis

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Search GEO for disease gene expression data for Vaginitis.

Pathways for genes affiliated with Vaginitis

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Pathways related to Vaginitis according to GeneCards/GeneDecks:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5ESR2, ESR1
29.5ESR2, ESR1
3
Show member pathways
9.5ESR1, ESR2
49.5ESR1, ESR2
59.5AR, IL1B
6
Show member pathways
FOXA transcription factor networks38
9.5AR, ESR1
79.3ESR1, ABCB1
89.1IL1B, IL10
99.1IL10, IL1B
109.1IL1B, IL10
11
Show member pathways
IL27-mediated signaling events38
9.1IL10, IL1B
129.1IL10, IL1B
139.1IL1B, IL10
149.1IL10, IL1B
15
Show member pathways
Nuclear Receptors38
9.1AR, ESR1, ESR2
169.1AR, ESR1, ESR2
17
Show member pathways
Cytoskeleton remodeling FAK signaling60
Development Endothelin 1 EDNRA transactivation of EGFR60
9.0IL1B, ESR1, ESR2
188.7ESR1, IL10, AR
198.5ABCB1, ESR2, ESR1, AR
208.3AR, IL1B, IL10, ESR2
21
Show member pathways
8.2ESR2, ESR1, IL10, IL1B

Compounds for genes affiliated with Vaginitis

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Compounds related to Vaginitis according to GeneCards/GeneDecks:

(show top 50)    (show all 152)
idCompoundScoreTop Affiliating Genes
1r,r-thc309.9ESR2, ESR1
217alpha estradiol459.9ESR2, ESR1
3ly 117018459.9ESR1, ESR2
4hpte45 3010.9AR, ESR2
5lasofoxifene459.9ESR1, ESR2
64-octylphenol459.9ESR2, ESR1
7isopropylparaben459.9ESR2, ESR1
8isobutylparaben459.9ESR1, ESR2
92,4,6-trichloro-4-biphenylol459.9ESR2, ESR1
10butylparaben459.8ESR1, ESR2
11methylparaben459.8ESR1, ESR2
12zeranol459.7ESR2, ESR1
134-hydroxy?aetamoxifen309.7ESR1, ESR2
14vinclozolin459.6ESR1, AR
15(z)-4-hydroxytamoxifen619.5ESR2, ESR1
164-tert-octylphenol459.5ESR1, ESR2, AR
17nandrolone45 2610.5ESR2, ESR1, AR
185alpha-androstane-3alpha,17beta-diol459.5AR, ESR1, ESR2
19exemestane45 51 61 1312.5ESR2, ESR1, AR
20bisphenol a459.5AR, ESR2, ESR1
21radicicol45 61 1311.5ESR1, DLAT, AR
22fulvestrant45 51 30 1312.5ESR2, ESR1, AR
23letrozole45 51 61 1312.5ESR2, AR, ESR1
24levonorgestrel45 61 30 1312.5ESR1, ESR2, AR
25bicalutamide45 61 1311.5ESR1, ESR2, AR
26steroidal459.5AR, ESR1, ESR2
2717beta-estradiol309.4ESR1, ESR2
2817beta-hydroxysteroid459.3AR, ESR1, ESR2
29naringenin45 1310.3ESR2, ESR1, ABCB1
30toremifene45 1310.3ESR2, ESR1, ABCB1
31estriol30 26 1311.3ESR2, ESR1, ABCB1
32progestins459.3AR, ESR1, ESR2
33lapatinib45 51 1311.3ABCB1, ESR1, AR
34ici 182,780619.2ESR1, ESR2
35estramustine45 139.9ABCB1, AR, ESR2, ESR1
36diethylstilbestrol45 30 1310.9ABCB1, ESR2, AR, ESR1
37estrone45 30 26 1311.9AR, ESR1, ABCB1, ESR2
38dihydrotestosterone45 30 26 1311.9ABCB1, ESR2, ESR1, AR
39tamoxifen45 51 30 1311.7ESR1, ESR2, ABCB1, AR
40ibuprofen45 30 51 26 1312.6IL1B, ABCB1, IL10
41vitamin d458.5ESR1, ESR2, IL10, AR
42mifepristone45 30 61 1311.4ABCB1, ESR2, ESR1, IL1B, AR
43actinomycin d458.4ABCB1, ESR2, ESR1, IL1B, AR
44genistein45 30 61 3 26 1313.4AR, ESR1, ESR2, ABCB1, IL1B
45methotrexate51 45 1310.4ABCB1, ESR1, IL10, IL1B
46ly294002458.2ESR1, IL1B, AR, IL10
47cycloheximide458.1ESR2, ESR1, IL10, IL1B, AR
48quercetin45 61 26 1311.1AR, IL10, ESR2, ABCB1, IL1B
49vegf458.0IL10, ESR1, AR, IL1B, ESR2
50dexamethasone45 51 30 1311.0ESR2, IL10, IL1B, ABCB1, AR

GO Terms for genes affiliated with Vaginitis

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Biological processes related to Vaginitis according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1uterus developmentGO:00600659.7ESR1, ESR2
2vagina developmentGO:00600689.7ESR1, ESR2
3intracellular estrogen receptor signaling pathwayGO:00305209.6ESR1, ESR2
4positive regulation of nitric oxide biosynthetic processGO:00454299.3ESR1, IL1B
5cellular response to estradiol stimulusGO:00713929.3IL10, ESR1
6transcription initiation from RNA polymerase II promoterGO:00063679.2ESR2, ESR1, AR
7positive regulation of transcription, DNA-templatedGO:00458938.7AR, IL1B, IL10
8positive regulation of sequence-specific DNA binding transcription factor activityGO:00510918.4ESR2, ESR1, IL10, IL1B
9signal transductionGO:00071658.3AR, IL1B, ESR1, ESR2
10cell-cell signalingGO:00072678.2AR, IL1B, IL10, ESR2, SH2D1A
11positive regulation of transcription from RNA polymerase II promoterGO:00459448.2AR, IL1B, IL10, ESR1

Molecular functions related to Vaginitis according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1estrogen response element bindingGO:00340569.7ESR1, ESR2
2estrogen receptor activityGO:00302849.7ESR1, ESR2
3core promoter sequence-specific DNA bindingGO:00010469.7ESR1, ESR2
4steroid bindingGO:00054969.6ESR1, ESR2
5ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:00048799.5AR, ESR2
6beta-catenin bindingGO:00080139.5AR, ESR1
7steroid hormone receptor activityGO:00037079.2ESR1, ESR2
8enzyme bindingGO:00198999.1ESR2, ESR1, AR

Products for genes affiliated with Vaginitis

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Sources for Vaginitis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet