Summaries for Vaginitis

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Wikipedia:63 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards based summary: Vaginitis, also known as infective vaginitis, is related to adenosarcoma and leiomyoma. An important gene associated with Vaginitis is SH2D1A (SH2 domain containing 1A), and among its related pathways are MNAR-PELP1 and Estrogen Receptor Interaction and Plasma membrane estrogen receptor signaling. The compounds r,r-thc and 17alpha estradiol have been mentioned in the context of this disorder. Affiliated tissues include testes, uterus and cervix, and related mouse phenotypes are digestive/alimentary and endocrine/exocrine gland.

Aliases & Classifications for Vaginitis

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Vaginitis, Aliases & Descriptions:

Name: Vaginitis 9
 
Infective Vaginitis 60


External Ids:

Disease Ontology9 DOID:2170
MeSH33 D014627
NCIt38 C26911

Related Diseases for Vaginitis

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Graphical network of the top 20 diseases related to Vaginitis:



Diseases related to vaginitis

Symptoms for Vaginitis

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Drugs & Therapeutics for Vaginitis

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Drug clinical trials:

Search ClinicalTrials for Vaginitis

Search NIH Clinical Center for Vaginitis

Genetic Tests for Vaginitis

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Anatomical Context for Vaginitis

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MalaCards organs/tissues related to Vaginitis:

31
Testes, Uterus, Cervix, Colon, Placenta, Neutrophil, Kidney, Ovary, Breast, Bone, Liver, Myeloid, T cells, Lymph node, Skin, Heart, Smooth muscle, Thyroid, Prostate, Lung, Monocytes, Pituitary

Animal Models for Vaginitis or affiliated genes

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Publications for Vaginitis

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Articles related to Vaginitis:

(show top 50)    (show all 2280)
idTitleAuthorsYear
1
Emphysematous vaginitis. (25551590)
2015
2
Intrapartum anti-disseminated intravascular coagulation therapy leading to successful vaginal delivery following intrauterine fetal death caused by placental abruption: a case report. (25532532)
2014
3
Accounting for Anovulation and Vaginal Thinning During Depot Medroxyprogesterone Acetate Use. (25217405)
2014
4
The role of physical examination in diagnosing common causes of vaginitis: a prospective study. (23019659)
2013
5
Co-infections with Ureaplasma parvum, Mycoplasma hominis and Chlamydia trachomatis in a human immunodeficiency virus positive woman with vaginal discharge. (23867681)
2013
6
Dosimetric comparison of multichannel with one single-channel vaginal cylinder for vaginal cancer treatments with high-dose-rate brachytherapy. (24080298)
2013
7
Innate immunity in the vagina (part I): estradiol inhibits HBD2 and elafin secretion by human vaginal epithelial cells. (23398087)
2013
8
Spectrum of vaginal discharge in a tertiary care setting. (24470998)
2013
9
Diverse vaginal microbiomes in reproductive-age women with vulvovaginal candidiasis. (24265786)
2013
10
Temporary endovascular balloon occlusion of the bilateral internal iliac arteries to control hemorrhage during laparoscopic-assisted vaginal hysterectomy for cervical myoma. (21658835)
2011
11
The prognostic role of human papillomavirus in patients with vaginal cancer. (21666483)
2011
12
In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models. (20805398)
2010
13
Early vaginal bleeding has no impact on markers used in first trimester aneuploidy screening. (20509154)
2010
14
Expression of occludin and zona occluden-1 and their morphologic changes in vagina mucosal cells in patients undergoing vaginal construction by using sigmoid colon]. (20003786)
2009
15
Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding. (19260253)
2009
16
Fetal acidosis from obstetric interventions during the first vaginal delivery. (19126504)
2008
17
Concurrent imperforate hymen, transverse vaginal septum, and unicornuate uterus: a case report. (17706513)
2007
18
Vaginal fibrosarcoma in a cow. (21851697)
2007
19
Analysis of vaginal recurrences in stage I endometrial adenocarcinoma. (17713101)
2007
20
Does vaginal bleeding influence first-trimester markers for Down syndrome? (17286311)
2007
21
Molecular evidence of congenital candidiasis associated with maternal candidal vaginitis. (16804443)
2006
22
Influence of exogenous reproductive hormones on specific antibody production in genital secretions after vaginal vaccination with recombinant cholera toxin B subunit in humans. (16467326)
2006
23
Cervical Cancer Screening for the Reluctant - HPV Testing of Air-Dried Vaginal Discharge. (23675011)
2006
24
Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients. (16006060)
2005
25
Information from your family doctor. Vaginitis. (15606062)
2004
26
Polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, local midtrimester cytokine response to vaginal flora, and subsequent preterm birth. (15507961)
2004
27
Vaginal misoprostol for induction of labour: a more effective agent than prostaglandin F2 alpha gel and prostaglandin E2 pessary. (14562597)
2002
28
Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans. (11705923)
2001
29
Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium. (10084314)
1999
30
Vaginal depth following reconstruction with pudendal thigh flaps in congenital vaginal atresia. (9030179)
1997
31
Long-term efficacy and safety of a disposable vaginal device (continence guard) in the treatment of female stress incontinence. (9449583)
1997
32
Vaginal stone in a male patient with true hermaphroditism. (9488939)
1997
33
Lactobacillus GG vaginal suppositories and vaginitis. (7615776)
1995
34
Depressed serum levels of human placental lactogen in first trimester vaginal bleeding. (7531935)
1995
35
Gartner's duct cyst with a single vaginal ectopic ureter and associated renal dysplasia or agenesis. (8301720)
1993
36
Split-dose metronidazole or single-dose tinidazole for the treatment of vaginal trichomoniasis. (1411848)
1992
37
Evaluation of a latex agglutination test for the identification of Candida species in vaginal discharge. (1496893)
1992
38
Vaginitis. (1956016)
1991
39
The treatment of vaginal atresia. (2028378)
1991
40
Allergic vaginitis mimicking bacterial vaginosis. (1965569)
1990
41
Prevalence of common infective agents of vaginitis. (2614050)
1989
42
Vaginal discharge and cystitis. (3399160)
1988
43
The role of benzydamine in the topical treatment of the so-called non-specific vaginitis. (3497131)
1987
44
Vaginal discharge. (3098348)
1986
45
The challenges of vaginal atresia and stenosis: Nigerian experience. (6144585)
1984
46
Double blind comparative study of tinidazole and ornidazole as a single dose treatment of vaginal trichomoniasis. (7000949)
1980
47
Single-dose treatment of vaginal trichomoniasis with tinidazole. (4617665)
1974
48
A case of pyomucocolpos due to a transverse vaginal septum]. (5106198)
1971
49
'Gathering' of tunica vaginal in the surgical cure of idiopathic hydrocele. (5651615)
1968
50
Experimental induction of uterine cervical and vaginal cancer in mice. (13629482)
1959

Variations for Vaginitis

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Expression for genes affiliated with Vaginitis

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Search GEO for disease gene expression data for Vaginitis.

Pathways for genes affiliated with Vaginitis

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Pathways related to Vaginitis according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5ESR2, ESR1
29.5ESR2, ESR1
3
Show member pathways
9.5ESR1, ESR2
49.5ESR1, ESR2
59.5AR, IL1B
6
Show member pathways
FOXA transcription factor networks36
9.5AR, ESR1
79.1IL1B, IL10
89.1IL10, IL1B
99.1IL1B, IL10
10
Show member pathways
IL27-mediated signaling events36
9.1IL10, IL1B
119.1IL10, IL1B
129.1IL1B, IL10
139.1IL10, IL1B
14
Show member pathways
Nuclear Receptors36
9.1AR, ESR1, ESR2
159.1AR, ESR1, ESR2
16
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
9.0IL1B, ESR1, ESR2
178.7ESR1, IL10, AR
188.5ABCB1, ESR2, ESR1, AR
198.3AR, IL1B, IL10, ESR2
20
Show member pathways
8.2ESR2, ESR1, IL10, IL1B

Compounds for genes affiliated with Vaginitis

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Compounds related to Vaginitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 152)
idCompoundScoreTop Affiliating Genes
1r,r-thc289.9ESR2, ESR1
217alpha estradiol439.9ESR2, ESR1
3ly 117018439.9ESR1, ESR2
4hpte43 2810.9AR, ESR2
5lasofoxifene439.9ESR1, ESR2
64-octylphenol439.9ESR2, ESR1
7isopropylparaben439.9ESR2, ESR1
8isobutylparaben439.9ESR1, ESR2
92,4,6-trichloro-4-biphenylol439.9ESR2, ESR1
10butylparaben439.8ESR1, ESR2
11methylparaben439.8ESR1, ESR2
12zeranol439.7ESR2, ESR1
134-hydroxy?aetamoxifen289.7ESR1, ESR2
14vinclozolin439.6ESR1, AR
15(z)-4-hydroxytamoxifen599.5ESR2, ESR1
164-tert-octylphenol439.5ESR1, ESR2, AR
17nandrolone43 2410.5ESR2, ESR1, AR
185alpha-androstane-3alpha,17beta-diol439.5AR, ESR1, ESR2
19exemestane43 49 59 1212.5ESR2, ESR1, AR
20bisphenol a439.5AR, ESR2, ESR1
21radicicol43 59 1211.5ESR1, DLAT, AR
22fulvestrant43 49 28 1212.5ESR2, ESR1, AR
23letrozole43 49 59 1212.5ESR2, AR, ESR1
24levonorgestrel43 59 28 1212.5ESR1, ESR2, AR
25bicalutamide43 59 1211.5ESR1, ESR2, AR
26steroidal439.5AR, ESR1, ESR2
2717beta-estradiol289.4ESR1, ESR2
2817beta-hydroxysteroid439.3AR, ESR1, ESR2
29naringenin43 1210.3ESR2, ESR1, ABCB1
30toremifene43 1210.3ESR2, ESR1, ABCB1
31estriol28 24 1211.3ESR2, ESR1, ABCB1
32progestins439.3AR, ESR1, ESR2
33lapatinib43 49 1211.3ABCB1, ESR1, AR
34ici 182,780599.2ESR1, ESR2
35estramustine43 129.9ABCB1, AR, ESR2, ESR1
36diethylstilbestrol43 28 1210.9ABCB1, ESR2, AR, ESR1
37estrone43 28 24 1211.9AR, ESR1, ABCB1, ESR2
38dihydrotestosterone43 28 24 1211.9ABCB1, ESR2, ESR1, AR
39tamoxifen43 49 28 1211.7ESR1, ESR2, ABCB1, AR
40ibuprofen43 28 49 24 1212.6IL1B, ABCB1, IL10
41vitamin d438.5ESR1, ESR2, IL10, AR
42mifepristone43 28 59 1211.4ABCB1, ESR2, ESR1, IL1B, AR
43actinomycin d438.4ABCB1, ESR2, ESR1, IL1B, AR
44genistein43 28 59 2 24 1213.4AR, ESR1, ESR2, ABCB1, IL1B
45methotrexate49 43 1210.4ABCB1, ESR1, IL10, IL1B
46ly294002438.2ESR1, IL1B, AR, IL10
47cycloheximide438.1ESR2, ESR1, IL10, IL1B, AR
48quercetin43 59 24 1211.1AR, IL10, ESR2, ABCB1, IL1B
49vegf438.0IL10, ESR1, AR, IL1B, ESR2
50dexamethasone43 49 28 1211.0ESR2, IL10, IL1B, ABCB1, AR

GO Terms for genes affiliated with Vaginitis

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Biological processes related to Vaginitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1uterus developmentGO:00600659.7ESR1, ESR2
2vagina developmentGO:00600689.7ESR1, ESR2
3intracellular estrogen receptor signaling pathwayGO:00305209.6ESR1, ESR2
4positive regulation of nitric oxide biosynthetic processGO:00454299.3ESR1, IL1B
5cellular response to estradiol stimulusGO:00713929.3IL10, ESR1
6transcription initiation from RNA polymerase II promoterGO:00063679.2ESR2, ESR1, AR
7positive regulation of transcription, DNA-templatedGO:00458938.7AR, IL1B, IL10
8positive regulation of sequence-specific DNA binding transcription factor activityGO:00510918.4ESR2, ESR1, IL10, IL1B
9signal transductionGO:00071658.3AR, IL1B, ESR1, ESR2
10cell-cell signalingGO:00072678.2AR, IL1B, IL10, ESR2, SH2D1A
11positive regulation of transcription from RNA polymerase II promoterGO:00459448.2AR, IL1B, IL10, ESR1

Molecular functions related to Vaginitis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1estrogen response element bindingGO:00340569.7ESR1, ESR2
2estrogen receptor activityGO:00302849.7ESR1, ESR2
3core promoter sequence-specific DNA bindingGO:00010469.7ESR1, ESR2
4steroid bindingGO:00054969.6ESR1, ESR2
5ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:00048799.5AR, ESR2
6beta-catenin bindingGO:00080139.5AR, ESR1
7steroid hormone receptor activityGO:00037079.2ESR1, ESR2
8enzyme bindingGO:00198999.1ESR2, ESR1, AR

Products for genes affiliated with Vaginitis

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Sources for Vaginitis

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3CDC
13ExPASy
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22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
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28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
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