MCID: VGN023
MIFTS: 54

Vaginitis malady

Summaries for Vaginitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards: Vaginitis, also known as vaginitis and vulvovaginitis, is related to vaginal discharge and vaginal cancer. An important gene associated with Vaginitis is DEFB4A (defensin, beta 4A). The compounds retinoic acid and paraffin have been mentioned in the context of this disorder. Affiliated tissues include testes, uterus and colon.

Aliases & Classifications for Vaginitis

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Sources:
8Disease Ontology, 60UMLS, 39NCIt, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

vaginitis 8
vaginitis and vulvovaginitis 8
vaginitis unspecified 8
infective vaginitis 60
vaginitis - non sp. 8
vaginitis nos 8


External Ids:

Disease Ontology8 DOID:2170
NCIt39 C26911
MeSH34 D014627

Related Diseases for Vaginitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Vaginitis:



Diseases related to vaginitis

Clinical Features for Vaginitis

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Drugs & Therapeutics for Vaginitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Vaginitis

Drug clinical trials:

Search ClinicalTrials for Vaginitis

Search NIH Clinical Center for Vaginitis

Search CenterWatch for Vaginitis

Genetic Tests for Vaginitis

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Anatomical Context for Vaginitis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Vaginitis:

32
Testes, Uterus, Colon, Cervix, Placenta, Kidney, Ovary, Liver, Bone, T cells, Breast, Skin, Myeloid, Lymph node, Heart, Smooth muscle, Prostate, Monocytes, Pituitary, Lung, Thyroid

Animal Models for Vaginitis or affiliated genes

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Publications for Vaginitis

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50PubMed
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Articles related to Vaginitis:

(show top 50)    (show all 2159)
idTitleAuthorsYear
1
Does histologic type correlate to outcome after pelvic exenteration for cervical and vaginal cancer? (23212765)
2013
2
Vulvar and vaginal cancer. (22640712)
2012
3
Assisted breech delivery with transverse vaginal septum. (24397081)
2012
4
European (IUSTI/WHO) guideline on the management of vaginal discharge, 2011. (21795415)
2011
5
Vaginal stenosis after toxic epidermal necrolysis. (20885170)
2010
6
Easiness of use and validity testing of VS-SENSE device for detection of abnormal vaginal flora and bacterial vaginosis. (20953405)
2010
7
Expression of occludin and zona occluden-1 and their morphologic changes in vagina mucosal cells in patients undergoing vaginal construction by using sigmoid colon]. (20003786)
2009
8
Lasofoxifene, a new selective estrogen receptor modulator for the treatment of osteoporosis and vaginal atrophy. (19640205)
2009
9
Vaginal estrogen therapy for the treatment of atrophic vaginitis. (19788364)
2009
10
Efficacy and safety of vaginal estriol and progesterone in postmenopausal women with atrophic vaginitis. (19390463)
2009
11
Factors affecting matrix metalloproteinase-8 levels in the vaginal and cervical fluids in the first and second trimester of pregnancy. (19654111)
2009
12
Effect of pregnancy and spontaneous delivery on the morphology of levator ani muscle and expression of vaginal nerve fibers]. (19087495)
2008
13
Frequency of cervical intraepithelial neoplasia and infectious agents for vaginitis in menstrual cycle phase. (17966219)
2007
14
Alterations of estrogen receptor-alpha and -beta in the anterior vaginal wall of women with urinary incontinence. (17287066)
2007
15
Vaginal removal of prolapsed pedunculated submucosal myoma during pregnancy. (17901039)
2007
16
Case report: Malignant peripheral nerve sheath tumor of the uterine cervix treated with radical vaginal trachelectomy. (16182351)
2006
17
Management and outcome of patients with combined vaginal septum, bifid uterus, and ipsilateral renal agenesis (Herlyn-Werner-Wunderlich syndrome). (16677898)
2006
18
Term pregnancy at the site of atresia following vaginal canalization in a case of uterus didelphys with hemivaginal atresia and ipsilateral renal agenesis. (17175503)
2006
19
Successful pregnancy after vaginal cancer treated with interferon. (15237591)
2004
20
Tritrichomonas foetus induces apoptotic cell death in bovine vaginal epithelial cells. (15213160)
2004
21
Efficacy and toxicity of MDR versus HDR brachytherapy for primary vaginal cancer. (12098007)
2002
22
Laurence-Moon-Biedl syndrome with vaginal atresia. (12477091)
2002
23
Resistance of T-cell receptor delta-chain-deficient mice to experimental Candida albicans vaginitis. (11598094)
2001
24
Local production of chemokines during experimental vaginal candidiasis. (10531235)
1999
25
Validation of a WHO algorithm with risk assessment for the clinical management of vaginal discharge in Mwanza, Tanzania. (10023356)
1998
26
Genital shedding of human immunodeficiency virus type 1 DNA during pregnancy: association with immunosuppression, abnormal cervical or vaginal discharge, and severe vitamin A deficiency. (8985196)
1997
27
Yogurt for candidal vaginitis. (1637033)
1992
28
The treatment of vaginal atresia. (2028378)
1991
29
Treatment of candidal vaginitis. A prospective randomized investigator-blind multicenter study comparing topically applied econazole with oral fluconazole. (1858500)
1991
30
Intrauterine pressures in labours induced by amniotomy and oxytocin or vaginal prostaglandin gel compared with spontaneous labour. (2059589)
1991
31
Esophageal candidiasis in AIDS. Successful therapy with clotrimazole vaginal tablets taken by mouth. (1995261)
1991
32
Diagnosis and treatment of chronic vaginitis in the bitch. (1858247)
1991
33
Imidazoles for vaginitis. (1951030)
1991
34
Induction of labour in nulliparas with poor cervical score: oxytocin or prostaglandin vaginal pessaries? (1804083)
1991
35
Allergic vaginitis. (2513724)
1989
36
Vaginal discharge of 'beads' and the new diapers. (3340492)
1988
37
Pregnancy outcomes after first-trimester vaginitis drug therapy. (3574801)
1987
38
Vaginal delivery impeded by a large fetal sacrococcygeal teratoma: anesthetic considerations. (3688507)
1987
39
Vaginal trichomoniasis in Sharkyia Governorate. (3487598)
1986
40
The challenges of vaginal atresia and stenosis: Nigerian experience. (6144585)
1984
41
Colposcopic and pathologic features in two cases of DES-related vaginal clear-cell adenocarcinoma. (6834354)
1983
42
Imperforate hymen and vaginal atresia and their associated anomalies. (6876046)
1983
43
Single vaginal ectopic ureter and Gartner's duct cyst with ipsilateral renal hypoplasia and dysplasia (or agenesis). (7176066)
1982
44
Longitudinal vaginal septum. (7117657)
1982
45
Vaginal discharge in the black pregnant patient: an evaluation of the relationship between symptomatology and diagnosis. (6773152)
1980
46
Pelvic exenteration for vaginal embryonal rhabdomyosarcoma: a review. (1090863)
1975
47
Treatment of vaginal trichomoniasis with a new anti-protozoal compound ( -chloromethyl-2-methyl-5-nitro-1-imidazole-ethanol). (4348437)
1973
48
IMMUNOLOGICAL AND THERAPEUTIC INVESTIGATIONS IN VAGINAL TRICHOMONIASIS. (14156377)
1963
49
A case of spontaneous labour complicated with transverse vaginal septum. (14821810)
1951
50
The treatment of mycotic vulvovaginitis with propionate vaginal jelly. (20286636)
1947

Genetic Variations for Vaginitis

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Expression for genes affiliated with Vaginitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vaginitis

Search GEO for disease gene expression data for Vaginitis.

Pathways for genes affiliated with Vaginitis

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Compounds for genes affiliated with Vaginitis

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Sources:
44Novoseek, 24HMDB, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 49PharmGKB
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Compounds related to Vaginitis according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1retinoic acid44 2412.3DEFB4A, DES, NCF2, OXT, SLC10A2, KRT13
2paraffin4411.2ESR1, KRT13, OXT, DSPP, DES, DEFB4A
3progesterone44 59 28 11 2415.2DEFB4A, DES, ANXA6, OXT, WNT4, ESR1
4estrogen4411.2DEFB4A, DES, DSPP, OXT, ESR1, ESRRG
5h2o24411.1DES, NCF2, DSPP, ANXA6, OXT
6testosterone44 59 11 2414.0DES, OXT, EPO, WNT4, ESR1
7estradiol44 11 2413.0ESRRG, OXT, DES
8vitamin d4411.0DSPP, EPO, KRT13, ESR1
9calcium44 49 11 2414.0DEFB4A, DES, NCF2, DSPP, ANXA6, OXT
10progestin4410.9ESR1, OXT, DES
11steroid4410.9DEFB4A, DES, OXT, ESR1, ESRRG
12estradiol benzoate4410.9OXT, ESR1
13nandrolone44 2411.9EPO, ESR1
14onapristone44 2811.8ESR1, OXT
15amoxicillin44 49 1112.7OXT, DSPP
16potassium chloride44 1111.6OXT, DSPP
17bisphenol a4410.6ESRRG, ESR1
18fumarate44 1111.3EPO, DSPP

GO Terms for genes affiliated with Vaginitis

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16Gene Ontology
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Cellular components related to Vaginitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00579610.7WNT4, DEFB4A, OGN

Biological processes related to Vaginitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of blood pressureGO:04577710.6OXT, NCF2
2response to hyperoxiaGO:05509310.5EPO, NCF2
3response to electrical stimulusGO:05160210.3EPO, OXT

Products for genes affiliated with Vaginitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Vaginitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet