MCID: VSC011
MIFTS: 62

Vasculitis

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Vasculitis

MalaCards integrated aliases for Vasculitis:

Name: Vasculitis 12 50 29 52 41 42 14 69
Autoimmune Vasculitis 50 69
Angiitis 12 50
Vasculitis, Autoimmune 50

Classifications:



External Ids:

Disease Ontology 12 DOID:865
MeSH 42 D014657
NCIt 47 C26912
UMLS 69 C0042384

Summaries for Vasculitis

NIH Rare Diseases : 50 the following summary is from orphanet, a european reference portal for information on rare diseases and orphan drugs.orpha number: 52759disease definitionvasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. giant-cell arteritis and takayasu arteritis; see these terms), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and kawasaki disease; see these terms), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin a vasculitis, and cutaneous leukocytoclastic angiitis; see these terms). vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. the degree of severity is variable, ranging from life or sight threatening disease (e.g. behçet disease, see this term) to relatively minor skin disease.visit the orphanet disease page for more resources. last updated: 2/10/2014

MalaCards based summary : Vasculitis, also known as autoimmune vasculitis, is related to churg-strauss syndrome and cryoglobulinemia, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Vasculitis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Innate Immune System. The drugs Azathioprine and alemtuzumab have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, skin and lung, and related phenotypes are hematopoietic system and cellular

Disease Ontology : 12 A vascular disease that is characterized by inflammation of the blood vessels.

MedlinePlus : 41 vasculitis is an inflammation of the blood vessels. it happens when the body's immune system attacks the blood vessel by mistake. it can happen because of an infection, a medicine, or another disease. the cause is often unknown. vasculitis can affect arteries, veins and capillaries. arteries are vessels that carry blood from the heart to the body's organs. veins are the vessels that carry blood back to the heart. capillaries are tiny blood vessels that connect the small arteries and veins. when a blood vessel becomes inflamed, it can narrow, making it more difficult for blood to get through close off completely so that blood can't get through stretch and weaken so much that it bulges. the bulge is called an aneurysm. if it bursts, it can cause dangerous bleeding inside the body. symptoms of vasculitis can vary, but usually include fever, swelling and a general sense of feeling ill. the main goal of treatment is to stop the inflammation. steroids and other medicines to stop inflammation are often helpful. nih: national heart, lung, and blood institute

Wikipedia : 72 Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation.... more...

Related Diseases for Vasculitis

Diseases related to Vasculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 811)
id Related Disease Score Top Affiliating Genes
1 churg-strauss syndrome 33.5 ICAM1 SELE TNF
2 cryoglobulinemia 32.4 CRP ELANE MPO
3 arthus reaction 30.5 CRP MPO TNF
4 myopathy 30.1 APOH MEFV TNF
5 sphenoid sinusitis 29.9 CD79A MPO PRTN3
6 cysticercosis 29.8 CD79A ICAM1 SELE
7 chronic myelomonocytic leukemia 29.8 CD79A CRP ICAM1 VCAM1
8 membranoproliferative glomerulonephritis 29.7 CD40LG CD79A TNF
9 bullous pemphigoid 29.7 ELANE PRTN3 SERPINB1
10 scabies 29.5 CRP ICAM1 MEFV TNF
11 uveitis 29.5 BPI CD40LG CD79A ICAM1 MPO TNF
12 chronic mucocutaneous candidiasis 29.3 CD40LG CD79A CRP
13 rabies 29.3 CD40LG CD79A
14 autoimmune hepatitis 29.3 CRP ICAM1 SELE THBD TNF VCAM1
15 pericarditis 29.3 APOH CRP SELE THBD VCAM1 VWF
16 leukodystrophy 29.3 CD40LG CD79A
17 arteriosclerosis 29.2 CD40LG CD79A ELANE SERPINA1
18 rheumatoid arthritis 29.2 CD40LG CD79A CRP ICAM1 TNF TNFSF13B
19 crest syndrome 29.1 CD40LG CD79A TNF
20 acute interstitial pneumonia 28.9 CD40LG CD79A ICAM1 TNF
21 rheumatic heart disease 28.9 CD40LG CD79A CRP PRTN3
22 calcinosis 28.9 CD40LG CD79A CRP TNF
23 diabetic angiopathy 28.8 CD40LG CD79A
24 myocardial infarction 28.8 CD40LG CRP ICAM1 MPO THBD TNF
25 systemic lupus erythematosus 28.7 APOH CD40LG CD79A CRP CTSG ICAM1
26 lymphoma 28.6 APOH CD40LG CD79A MEFV PRTN3 TNF
27 rubella 28.6 APOH CD40LG
28 granuloma annulare 28.4 CD40LG CD79A ICAM1 MPO PRTN3 VCAM1
29 asthma 28.0 CD40LG CD79A ELANE ICAM1 SELE TNF
30 chickenpox 22.5 APOH BPI CD40LG CD79A CRP CTSG
31 hypersensitivity vasculitis 12.2
32 retinal vasculitis 12.2
33 hypocomplementemic urticarial vasculitis 12.2
34 rheumatoid vasculitis 12.2
35 lymphocytic vasculitis 12.2
36 anca-associated vasculitis 12.1
37 allergic cutaneous vasculitis 12.0
38 vasculitis syndromes of the central and peripheral nervous systems 12.0
39 central nervous system vasculitis 11.9
40 immunoglobulin a vasculitis 11.9
41 drug-induced vasculitis 11.8
42 unclassified vasculitis 11.8
43 adenosine deaminase 2 deficiency 11.7
44 postinfectious vasculitis 11.7
45 primary angiitis of the central nervous system 11.6
46 livedoid vasculopathy 11.6
47 irvan syndrome 11.5
48 eosinophilic granulomatosis with polyangiitis 11.5
49 erythema elevatum diutinum 11.4
50 polyarteritis nodosa, childhood-onset 11.3

Graphical network of the top 20 diseases related to Vasculitis:



Diseases related to Vasculitis

Symptoms & Phenotypes for Vasculitis

UMLS symptoms related to Vasculitis:


angina pectoris, chest pain, edema

MGI Mouse Phenotypes related to Vasculitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.16 VCAM1 VWF CD40LG CD79A CTSG ELANE
2 cellular MP:0005384 10.1 CD40LG CD79A ICAM1 MEFV PRTN3 S100A9
3 homeostasis/metabolism MP:0005376 10.03 APOH CD40LG CD79A CRP ELANE ICAM1
4 immune system MP:0005387 9.89 CRP CTSG ELANE ICAM1 MEFV MPO
5 mortality/aging MP:0010768 9.47 THBD TNF VCAM1 VWF SELE SERPINB1

Drugs & Therapeutics for Vasculitis

Drugs for Vasculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 265)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azathioprine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 446-86-6 2265
2
alemtuzumab Approved, Investigational Phase 4,Phase 2,Phase 1 216503-57-0
3
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
4
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
5
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
6
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
7
Dalteparin Approved Phase 4,Phase 3,Phase 1 9005-49-6
8
Heparin Approved, Investigational Phase 4,Phase 3,Phase 1 9005-49-6 772 46507594
9
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 4 67-73-2 6215
10
Methotrexate Approved Phase 4,Phase 3,Phase 2 1959-05-2, 59-05-2 126941
11
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
12
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
13
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
15
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
16
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
17
Octreotide Approved, Investigational Phase 4 83150-76-9 383414 6400441
18
Somatostatin Approved Phase 4 38916-34-6, 51110-01-1 53481605
19
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
20
Anthralin Approved Phase 4 1143-38-0
21
Tazarotene Approved, Investigational Phase 4 118292-40-3 5381
22
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
23
Glatiramer Acetate Approved, Investigational Phase 4 147245-92-9 3081884
24
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
25
Ibuprofen Approved Phase 4 15687-27-1 3672
26
Dapsone Approved, Investigational Phase 4,Phase 2 80-08-0 2955
27
Menthol Approved Phase 4 2216-51-5 16666
28
Pravastatin Approved Phase 4,Phase 2 81093-37-0 54687
29
Ceftazidime Approved Phase 4 78439-06-2, 72558-82-8 5481173
30
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
31
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 143 6006
32 Tocopherol Approved, Nutraceutical Phase 4
33
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
34 Antibodies Phase 4,Phase 2,Phase 3,Phase 1
35 Antibodies, Antineutrophil Cytoplasmic Phase 4,Phase 3,Phase 2
36 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1
37 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 2
38 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Immunoglobulins Phase 4,Phase 2,Phase 3,Phase 1
40 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Vaccines Phase 4,Phase 3,Phase 2
42 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Antiemetics Phase 4,Phase 2,Phase 3
44 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
45 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
46 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
47 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
48 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
49 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
50 Hormones Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 394)

id Name Status NCT ID Phase Drugs
1 Prevention of Relapses in Proteinase 3 (PR3)-Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis Unknown status NCT00128895 Phase 4 azathioprine
2 Alemtuzumab for ANCA Associated Refractory Vasculitis Unknown status NCT01405807 Phase 4 Alemtuzumab
3 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
4 CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors Unknown status NCT00400075 Phase 4 azathioprine;cyclophosphamide
5 The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease Unknown status NCT01306955 Phase 4 methylorednisolone
6 CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors Unknown status NCT00399399 Phase 4 azathioprine;cyclophosphamide
7 Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis Unknown status NCT01400464 Phase 4 Prednisone therapy and pharmacokinetic
8 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4 Dalteparin;Dalteparin
9 Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease Unknown status NCT00720928 Phase 4 flucinolone acetonide
10 Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Completed NCT00307671 Phase 4 prednisone, methylprednisolone,cyclophosphamides;Cyclophosphamide, Azathioprine,prednisone,methylprednisolone;Mycophenolate mofetil,methotrexate
11 Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis Completed NCT03222687 Phase 4 tacrolimus;prednisone
12 Study of the Influence of Plasma Exchange on the Pharmacokinetics of Rituximab Completed NCT00820469 Phase 4 Rituximab 375;rituximab 1000
13 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
14 Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis Completed NCT00940862 Phase 4
15 The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF Completed NCT02602028 Phase 4 colchicine
16 Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age Completed NCT01985997 Phase 4
17 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
18 Glatiramer Acetate for Multiple Sclerosis With Autoimmune Comorbidities Completed NCT01456416 Phase 4
19 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4 prednisone
20 Study of Combined Therapy of Aspirin and "IVIG-SN" in Kawasaki Disease Completed NCT01524939 Phase 4 immunoglobulin G
21 Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins Completed NCT02346058 Phase 4 Esarin Gel
22 HSP-glomerulonephritis Trial: MP vs CyA Completed NCT00425724 Phase 4 Methylprednisolone pulses plus prednisone versus Cyclosporine A
23 Topical Diclofenac Gel in Patients With Superficial Inflammation of the Veins Completed NCT00377806 Phase 4 Diclofenac gel
24 Management of Superficial Thrombophlebitis Completed NCT00264381 Phase 4 Dalteparin sodium injection
25 Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing Recruiting NCT02749292 Phase 4 Rituximab
26 Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis Recruiting NCT03066869 Phase 4 H.P. ACTHAR GEL
27 Low-dose Glucocorticoid Vasculitis Induction Study Recruiting NCT02198248 Phase 4 Rituximab;Glucocorticoids
28 A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis Recruiting NCT02115997 Phase 4 Methylprednisolone;Prednisone;Rituximab
29 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4 Dapsone
30 A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease Recruiting NCT02951234 Phase 4
31 Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Recruiting NCT02626845 Phase 4 Rituximab
32 Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission. Recruiting NCT03244709 Phase 4 Tocilizumab
33 Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation Recruiting NCT03133767 Phase 4 Lactated Ringer Solution;Normal Saline 0.9% Infusion Solution Bag
34 Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Active, not recruiting NCT02169219 Phase 4 Glucocorticoids;Rituximab
35 The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis Enrolling by invitation NCT02082717 Phase 4 potassium chloride replacement;Experimental - 4% Sodium Bicarbonate
36 Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis. Not yet recruiting NCT03164473 Phase 4 Rituximab;Azathioprine;Placebo-rituximab;Placebo-azathioprine
37 Normal Saline Versus Heparinized Solution Flush for Maintaining Patency of Peripheral Venous Catheters in Children Suspended NCT01794767 Phase 4 0,9% NaCl flush;Heparin 50U/ml
38 Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels Terminated NCT00578578 Phase 4
39 Anti-Oxidant Therapy In Chronic Renal Insufficiency (ATIC) Study Terminated NCT00384618 Phase 4 pravastatin;vitamin E
40 Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") Terminated NCT00747461 Phase 4
41 Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy Terminated NCT02373397 Phase 4
42 Prolonging the Duration of Peripheral Venous Catheters in Cystic Fibrosis People Terminated NCT00418470 Phase 4
43 WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides Unknown status NCT00349674 Phase 3 Azathioprine: 2 mg/kg/day;methotrexate 0.3 mg/kg/week, to a maximum and optimal dose of 25 mg/week
44 Mycophenolate Mofetil for Treatment of Relapses of Wegener's Disease or Microscopic Polyangiitis (MPA) Unknown status NCT00103792 Phase 3 mycophenolate mofetil;cyclophosphamide
45 Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB) Unknown status NCT00167583 Phase 3 Cyclosporin A;Interferon-alpha2a
46 Pain and Music Therapy in Patients Suffering Arteritis Unknown status NCT01323504 Phase 3
47 Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change Unknown status NCT00103636 Phase 2, Phase 3
48 Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery Unknown status NCT01297959 Phase 3 E-101 Solution 300 GU/ml;Saline solution
49 Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica Unknown status NCT01423591 Phase 3 infliximab;inactive powder
50 Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis Completed NCT00414128 Phase 2, Phase 3 mycophenolate mofetil;cyclophosphamide

Search NIH Clinical Center for Vasculitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: vasculitis

Genetic Tests for Vasculitis

Genetic tests related to Vasculitis:

id Genetic test Affiliating Genes
1 Vasculitis 29

Anatomical Context for Vasculitis

MalaCards organs/tissues related to Vasculitis:

39
Neutrophil, Skin, Lung, Endothelial, T Cells, Heart, B Cells

Publications for Vasculitis

Articles related to Vasculitis:

(show top 50) (show all 2761)
id Title Authors Year
1
Bilateral idiopathic retinal vasculitis following coxsackievirus A4 infection: a case report. ( 28724375 )
2017
2
Multicolor flow cytometric analysis of TLR2 and TLR9 expression and function in NK cells from patients with ANCA-associated vasculitis. ( 28834234 )
2017
3
Association of primary central nervous system vasculitis with the presence of specific human leucocyte antigen gene variant. ( 28734234 )
2017
4
Cerebral large-vessel vasculitis as an unusual manifestation of POEMS syndrome. ( 28432517 )
2017
5
Nodular Vasculitis in a Patient With Crohn's Disease on Vedolizumab. ( 28953016 )
2017
6
Antineutrophil cytoplasmic antibodies associated vasculitis in patient with Crohn's disease treated with adalimumab. ( 28946973 )
2017
7
Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis. ( 28810044 )
2017
8
Case of combination therapy to treat lupus retinal vasculitis refractory to steroids. ( 28237161 )
2017
9
Vancomycin-Induced Leukocytoclastic Vasculitis and Acute Renal Failure Due to Tubulointerstitial Nephritis. ( 28943633 )
2017
10
Cutaneous vasculitis: a presentation with endocarditis to keep in mind. ( 28954130 )
2017
11
A New Complication Associated with the Use of Prophylactic Intracameral Antibiotics: Hemorrhagic Occlusive Retinal Vasculitis. ( 28433121 )
2017
12
Rheumatoid Vasculitis: A Diminishing Yet Devastating Menace. ( 28631066 )
2017
13
Recommendations of the Brazilian Society of Rheumatology for the induction therapy of ANCA-associated vasculitis. ( 28754431 )
2017
14
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis. ( 28416516 )
2017
15
Response to: 'Mortality in ANCA-associated vasculitis: mission incomplete' by Moiseev et al. ( 28710096 )
2017
16
Tuberculosis mimicking primary systemic vasculitis: not to be missed! ( 28092221 )
2017
17
The BVAS is an independent predictor of cardiovascular events and cardiovascular disease-related mortality in patients with ANCA-associated vasculitis: A study of 504 cases in a single Chinese center. ( 28917713 )
2017
18
The epidemiology of ANCA associated vasculitis in Olmsted County, Minnesota (USA): a 20 year population-based study. ( 28881446 )
2017
19
Adenosine Deaminase 2 Deficiency: More Than Monogenic Vasculitis. ( 28786259 )
2017
20
Cutaneous leukocytoclastic vasculitis: the role of lymphocytes and related immune markers. ( 28951703 )
2017
21
Pulmonary Involvement in Antineutrophil Cytoplasmic Antibodies (ANCA)-associated Vasculitis: The Influence of ANCA Subtype. ( 28765242 )
2017
22
Paediatric anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: an update on renal management. ( 28062909 )
2017
23
Clinical Outcome of Retinal Vasculitis and Predictors for Prognosis of Ischemic Retinal Vasculitis. ( 28263735 )
2017
24
Pitfalls of PACNS: A Rare Case of Central Nervous System Vasculitis Associated with Toxoplasmosis. ( 28765346 )
2017
25
Erythema induratum (nodular vasculitis) associated with Takayasu arteritis. ( 28470150 )
2017
26
Persistent Placoid Maculopathy Complicated by Cerebral Vasculitis. ( 28809763 )
2017
27
Voriconazole-induced periostitis deformans: serial imaging in a patient with ANCA vasculitis. ( 28866833 )
2017
28
Magnetic resonance imaging in central nervous system vasculitis in a patient affected by crioglobulin-negative hepatitis C virus infection: A likely correlation. ( 28735554 )
2017
29
Retinal Vasculitis and Choroidopathy in Pediatric-Onset Mixed Connective Tissue Disease. ( 28937479 )
2017
30
The Effects of Plasma Exchange on Severe Vasculitis with Diffuse Alveolar Hemorrhage. ( 28050000 )
2017
31
Multifocal Choroiditis with Retinal Vasculitis, Optic Neuropathy, and Keratoconus in a Young Saudi Male. ( 28936058 )
2017
32
Case report of a 28-year-old male with the rapid progression of steroid-resistant central nervous system vasculitis diagnosed by a brain biopsy. ( 28804113 )
2017
33
Usual and Unusual Manifestations of Systemic and Central Nervous System Vasculitis. ( 27894445 )
2017
34
Central nervous system vasculitis in systemic lupus erythematosus: a case series report in a tertiary referral centre. ( 28420057 )
2017
35
Identification and phenotyping of circulating autoreactive proteinase 3-specific B cells in patients with PR3-ANCA associated vasculitis and healthy controls. ( 28870527 )
2017
36
Intracameral Antibiotics in the Shadow of Hemorrhagic Occlusive Retinal Vasculitis. ( 28433122 )
2017
37
A case of new-onset rheumatoid vasculitis becoming evident in the course of treatment for Pneumocystis jirovecii pneumonia. ( 28539558 )
2017
38
Hepatitis B virus induced cytoplasmic antineutrophil cytoplasmic antibody-mediated vasculitis causing subarachnoid hemorrhage, acute transverse myelitis, and nephropathy: a case report. ( 28366165 )
2017
39
Can rheumatoid vasculitis predate a diagnosis of rheumatoid arthritis? ( 28293454 )
2017
40
Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over. ( 28916770 )
2017
41
Central nervous system vasculitis in adults: An update. ( 28087351 )
2017
42
Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low-dose methotrexate. ( 28932785 )
2017
43
Positive predictive value of hospital discharge diagnosis code to identify immunoglobulin A vasculitis in France: A validation study. ( 28651748 )
2017
44
Erythema elevatum diutinum in Crohn's disease-associated Spondyloarthritis - a rare vasculitis, an unusual association. ( 28917218 )
2017
45
Benign Atrophic Papulosis (Degos Disease) With Lymphocytic Vasculitis and Lichen Sclerosus-Like Features. ( 28244939 )
2017
46
Focal Hemispheric Central Nervous System Vasculitis: An Unusual Form Of Primary Angiitis. ( 28718271 )
2017
47
Complement regulatory proteins in kidneys of patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. ( 28940198 )
2017
48
Classification of large vessel vasculitis: Can we separate giant cell arteritis from Takayasu arteritis? ( 28774474 )
2017
49
Non-invasive method of monitoring retinal vasculitis in patients with birdshot chorioretinopathy using optical coherence tomography. ( 28844053 )
2017
50
Primary central nervous system vasculitis and its mimicking diseases - clinical features, outcome, comorbidities and diagnostic results - A case control study. ( 28324788 )
2017

Variations for Vasculitis

Expression for Vasculitis

Search GEO for disease gene expression data for Vasculitis.

Pathways for Vasculitis

Pathways related to Vasculitis according to GeneCards Suite gene sharing:

(show all 20)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.25 CD40LG ICAM1 PRTN3 TNF TNFSF13B VCAM1
2
Show member pathways
13.15 BPI CD40LG CD79A CRP CTSG ELANE
3 12.47 CD40LG CD79A MPO TNF TNFSF13B VCAM1
4
Show member pathways
12.28 BPI CTSG ELANE PRTN3 S100A9
5 12.02 ICAM1 SELE THBD TNF VCAM1
6 12 CD40LG ICAM1 SELE VCAM1
7 11.86 ICAM1 SELE TNF VCAM1
8 11.8 ICAM1 SELE THBD TNF VCAM1
9 11.74 CD40LG ICAM1 TNF TNFSF13B VCAM1
10 11.71 ICAM1 TNF TNFSF13B
11
Show member pathways
11.68 CD40LG TNF TNFSF13B
12 11.64 ELANE MPO PRTN3
13
Show member pathways
11.6 CD40LG TNF TNFSF13B
14 11.56 CD40LG ICAM1 TNF TNFSF13B VCAM1
15
Show member pathways
11.45 CD40LG ICAM1 SELE TNF VCAM1
16 11.44 ELANE ICAM1 MPO TNF
17 11.38 ICAM1 SELE VCAM1
18 11.28 ICAM1 SELE TNF VCAM1
19 11.04 CD40LG ICAM1 SELE TNF VCAM1
20 10.66 ICAM1 MPO TNF VCAM1

GO Terms for Vasculitis

Cellular components related to Vasculitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.92 APOH CD40LG CTSG ELANE ICAM1 THBD
2 external side of plasma membrane GO:0009897 9.8 CD40LG CD79A ICAM1 TNF VCAM1
3 extracellular region GO:0005576 9.8 APOH BPI CD40LG CRP CTSG ELANE
4 membrane raft GO:0045121 9.73 CD79A ICAM1 SELE TNF
5 azurophil granule lumen GO:0035578 9.65 BPI CTSG ELANE MPO PRTN3
6 secretory granule GO:0030141 9.63 CTSG ELANE MPO
7 extracellular matrix GO:0031012 9.55 APOH CTSG PRTN3 S100A9 VWF
8 extracellular space GO:0005615 9.55 APOH BPI CD40LG CRP CTSG ELANE
9 extracellular exosome GO:0070062 10.18 APOH BPI CRP CTSG ELANE ICAM1

Biological processes related to Vasculitis according to GeneCards Suite gene sharing:

(show all 31)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.95 CD40LG CRP MEFV S100A9 SELE TNF
2 extracellular matrix organization GO:0030198 9.92 ICAM1 TNF VCAM1 VWF
3 regulation of immune response GO:0050776 9.92 CD40LG ICAM1 TNFSF13B VCAM1
4 blood coagulation GO:0007596 9.9 PRTN3 SERPINA1 THBD VWF
5 leukocyte migration GO:0050900 9.89 ELANE ICAM1 SELE THBD TNF
6 defense response to bacterium GO:0042742 9.88 BPI CTSG ELANE MPO S100A9 TNF
7 neutrophil degranulation GO:0043312 9.86 BPI CTSG ELANE MPO PRTN3 S100A9
8 B cell differentiation GO:0030183 9.81 CD40LG CD79A VCAM1
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.81 CD40LG ICAM1 S100A9 TNF
10 positive regulation of T cell proliferation GO:0042102 9.79 CD40LG TNFSF13B VCAM1
11 hemostasis GO:0007599 9.76 SERPINA1 THBD VWF
12 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.73 ICAM1 SELE VCAM1
13 defense response to fungus GO:0050832 9.67 CTSG ELANE MPO S100A9
14 negative regulation of blood coagulation GO:0030195 9.65 APOH THBD
15 positive regulation of immune response GO:0050778 9.64 CTSG ELANE
16 negative regulation of fibrinolysis GO:0051918 9.64 APOH THBD
17 negative regulation of lipid storage GO:0010888 9.63 CRP TNF
18 leukocyte tethering or rolling GO:0050901 9.63 SELE TNF VCAM1
19 leukocyte cell-cell adhesion GO:0007159 9.62 CD40LG ICAM1 SELE VCAM1
20 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.61 ELANE TNF
21 leukocyte migration involved in inflammatory response GO:0002523 9.61 ELANE S100A9 SELE
22 acute inflammatory response to antigenic stimulus GO:0002438 9.59 ELANE ICAM1
23 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.58 ICAM1 TNF
24 response to yeast GO:0001878 9.57 ELANE MPO
25 membrane to membrane docking GO:0022614 9.55 ICAM1 VCAM1
26 antimicrobial humoral response GO:0019730 9.55 BPI CTSG ELANE PRTN3 S100A9
27 immunoglobulin secretion GO:0048305 9.54 CD40LG TNFSF13B
28 regulation of immunoglobulin secretion GO:0051023 9.52 CD40LG TNF
29 negative regulation of growth of symbiont in host GO:0044130 9.26 CTSG ELANE MPO TNF
30 response to lipopolysaccharide GO:0032496 9.17 CTSG ELANE ICAM1 MPO SELE THBD
31 immune response GO:0006955 10.04 BPI CD40LG CTSG TNF TNFSF13B

Molecular functions related to Vasculitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 9.46 APOH CTSG ELANE MPO
2 tumor necrosis factor receptor binding GO:0005164 9.13 CD40LG TNF TNFSF13B
3 protease binding GO:0002020 8.92 ELANE SERPINA1 TNF VWF
4 protein binding GO:0005515 10.13 APOH CD40LG CD79A CRP CTSG ELANE

Sources for Vasculitis

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