MCID: VSC011
MIFTS: 62

Vasculitis malady

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Vasculitis

Aliases & Descriptions for Vasculitis:

Name: Vasculitis 12 50 29 52 41 42 14 69
Autoimmune Vasculitis 50 69
Angiitis 12 50
Vasculitis, Autoimmune 50

Classifications:



External Ids:

Disease Ontology 12 DOID:865
MeSH 42 D014657
NCIt 47 C26912
UMLS 69 C0042384

Summaries for Vasculitis

MedlinePlus : 41 vasculitis is an inflammation of the blood vessels. it happens when the body's immune system attacks the blood vessel by mistake. it can happen because of an infection, a medicine, or another disease. the cause is often unknown. vasculitis can affect arteries, veins and capillaries. arteries are vessels that carry blood from the heart to the body's organs. veins are the vessels that carry blood back to the heart. capillaries are tiny blood vessels that connect the small arteries and veins. when a blood vessel becomes inflamed, it can narrow, making it more difficult for blood to get through close off completely so that blood can't get through stretch and weaken so much that it bulges. the bulge is called an aneurysm. if it bursts, it can cause dangerous bleeding inside the body. symptoms of vasculitis can vary, but usually include fever, swelling and a general sense of feeling ill. the main goal of treatment is to stop the inflammation. steroids and other medicines to stop inflammation are often helpful. nih: national heart, lung, and blood institute

MalaCards based summary : Vasculitis, also known as autoimmune vasculitis, is related to uveitis and rheumatoid arthritis, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Vasculitis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Heparin and Cyclosporine have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, endothelial and lung, and related phenotypes are hematopoietic system and cellular

Disease Ontology : 12 A vascular disease that is characterized by inflammation of the blood vessels.

Related Diseases for Vasculitis

Diseases related to Vasculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 776)
id Related Disease Score Top Affiliating Genes
1 uveitis 30.0 BPI CD40LG CD79A ICAM1 MPO TNF
2 rheumatoid arthritis 30.0 CD40LG CD79A CRP ICAM1 PRTN3 TNF
3 urticaria 29.8 CRP MPO TNF
4 cutaneous polyarteritis nodosa 29.8 CD40LG CD79A
5 arteriosclerosis 29.5 CD40LG CD79A ELANE SERPINA1
6 chronic mucocutaneous candidiasis 29.5 CD40LG CD79A CRP
7 fasciitis 29.5 BPI CTSG ELANE MPO SERPINA1 TNF
8 ischemic optic neuropathy 29.5 APOH CRP VWF
9 herpes simplex 29.4 APOH THBD VWF
10 histiocytosis 29.4 CD79A CRP ELANE TNF
11 membranoproliferative glomerulonephritis 29.4 APOH CD40LG CD79A CRP PRTN3 TNF
12 sparganosis 29.3 CD79A ICAM1 SELE
13 rabies 29.3 CD40LG CD79A
14 myocardial infarction 29.3 CRP ICAM1 MPO SELE THBD TNF
15 pericarditis 29.2 APOH CRP SELE THBD VCAM1 VWF
16 celiac disease 29.2 CD40LG CD79A CRP TNF
17 calcinosis 29.2 CD40LG CD79A CRP TNF
18 sialadenitis 29.1 APOH THBD VWF
19 astrocytoma 29.0 CD40LG MPO PRTN3 THBD TNF
20 renal oncocytoma 28.9 ELANE SERPINA1 SERPINB1
21 hypersensitivity vasculitis 12.3
22 retinal vasculitis 12.2
23 hypocomplementemic urticarial vasculitis 12.2
24 rheumatoid vasculitis 12.2
25 lymphocytic vasculitis 12.2
26 anca-associated vasculitis 12.1
27 allergic cutaneous vasculitis 12.1
28 vasculitis syndromes of the central and peripheral nervous systems 12.0
29 central nervous system vasculitis 11.9
30 drug-induced vasculitis 11.9
31 immunoglobulin a vasculitis 11.9
32 unclassified vasculitis 11.8
33 livedoid vasculopathy 11.7
34 adenosine deaminase 2 deficiency 11.7
35 postinfectious vasculitis 11.7
36 primary angiitis of the central nervous system 11.7
37 churg-strauss syndrome 11.5
38 irvan syndrome 11.5
39 eosinophilic granulomatosis with polyangiitis 11.5
40 erythema elevatum diutinum 11.4
41 polyarteritis nodosa, childhood-onset 11.3
42 wegener granulomatosis 11.3
43 temporal arteritis 11.3
44 microscopic polyangiitis 11.1
45 kawasaki disease 11.1
46 cryoglobulinemia 11.1
47 systemic lupus erythematosus 11.0
48 polyarteritis nodosa 11.0
49 purpura 11.0
50 juvenile temporal arteritis 11.0

Graphical network of the top 20 diseases related to Vasculitis:



Diseases related to Vasculitis

Symptoms & Phenotypes for Vasculitis

UMLS symptoms related to Vasculitis:


angina pectoris, chest pain, edema

MGI Mouse Phenotypes related to Vasculitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.16 PRTN3 S100A9 SELE SERPINB1 THBD TNF
2 cellular MP:0005384 10.1 CD40LG CD79A ICAM1 MEFV PRTN3 S100A9
3 homeostasis/metabolism MP:0005376 10.03 APOH CD40LG CD79A CRP ELANE ICAM1
4 immune system MP:0005387 9.89 CD40LG CD79A CRP CTSG ELANE ICAM1
5 mortality/aging MP:0010768 9.47 MEFV MPO S100A9 APOH CD40LG CTSG

Drugs & Therapeutics for Vasculitis

Drugs for Vasculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 257)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 1 9005-49-6 772 46507594
2
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Early Phase 1 79217-60-0, 59865-13-3 5284373 6435893
3
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
4
Methotrexate Approved Phase 4,Phase 3,Phase 2 1959-05-2, 59-05-2 126941
5
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
6
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
7
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
8
Azathioprine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 446-86-6 2265
9
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
10
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
12
alemtuzumab Approved, Investigational Phase 4,Phase 2,Phase 1 216503-57-0
13
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
14
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 4 67-73-2 6215
15
Dalteparin Approved Phase 4,Phase 3,Phase 1 9041-08-1
16
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
17
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
18
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
19
Ibuprofen Approved Phase 4 15687-27-1 3672
20
Octreotide Approved, Investigational Phase 4 83150-76-9 383414 6400441
21
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
22
Glatiramer Acetate Approved, Investigational Phase 4 147245-92-9 3081884
23
Tazarotene Approved, Investigational Phase 4 118292-40-3 5381
24
Somatostatin Approved Phase 4 38916-34-6, 51110-01-1 53481605
25
Dapsone Approved, Investigational Phase 4,Phase 2 80-08-0 2955
26
Menthol Approved Phase 4 2216-51-5 16666
27
Pravastatin Approved Phase 4,Phase 2 81093-37-0 54687
28
Ceftazidime Approved Phase 4 78439-06-2 5481173
29
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 54575, 6560146 143
30
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
31
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
32 calcium heparin Phase 4,Phase 3,Phase 1
33 Prednisolone acetate Phase 4,Phase 3,Phase 2
34 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
35 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
36 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
37 Folic Acid Antagonists Phase 4,Phase 3,Phase 2
38 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Neuroprotective Agents Phase 4,Phase 2,Phase 3
40 Cyclooxygenase Inhibitors Phase 4
41 Heparin, Low-Molecular-Weight Phase 4,Phase 3,Phase 1
42 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
43 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3,Phase 1
44 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
46 Hormones Phase 4,Phase 2,Phase 3,Phase 1
47 Vaccines Phase 4,Phase 3,Phase 2
48 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
49 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
50 Vitamin B Complex Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 372)
id Name Status NCT ID Phase
1 Prevention of Relapses in Proteinase 3 (PR3)-Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis Unknown status NCT00128895 Phase 4
2 Alemtuzumab for ANCA Associated Refractory Vasculitis Unknown status NCT01405807 Phase 4
3 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
4 CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors Unknown status NCT00400075 Phase 4
5 The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease Unknown status NCT01306955 Phase 4
6 CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors Unknown status NCT00399399 Phase 4
7 Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis Unknown status NCT01400464 Phase 4
8 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4
9 Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease Unknown status NCT00720928 Phase 4
10 Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Completed NCT00307671 Phase 4
11 Study of the Influence of Plasma Exchange on the Pharmacokinetics of Rituximab Completed NCT00820469 Phase 4
12 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
13 Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis Completed NCT00940862 Phase 4
14 The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF Completed NCT02602028 Phase 4
15 Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age Completed NCT01985997 Phase 4
16 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4
17 Glatiramer Acetate for Multiple Sclerosis With Autoimmune Comorbidities Completed NCT01456416 Phase 4
18 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4
19 Study of Combined Therapy of Aspirin and "IVIG-SN" in Kawasaki Disease Completed NCT01524939 Phase 4
20 Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins Completed NCT02346058 Phase 4
21 HSP-glomerulonephritis Trial: MP vs CyA Completed NCT00425724 Phase 4
22 Topical Diclofenac Gel in Patients With Superficial Inflammation of the Veins Completed NCT00377806 Phase 4
23 Management of Superficial Thrombophlebitis Completed NCT00264381 Phase 4
24 Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing Recruiting NCT02749292 Phase 4
25 Low-dose Glucocorticoid Vasculitis Induction Study Recruiting NCT02198248 Phase 4
26 A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis Recruiting NCT02115997 Phase 4
27 Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome Recruiting NCT02550080 Phase 4
28 A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease Recruiting NCT02951234 Phase 4
29 Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Recruiting NCT02626845 Phase 4
30 Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Active, not recruiting NCT02169219 Phase 4
31 The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis Enrolling by invitation NCT02082717 Phase 4
32 Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis Not yet recruiting NCT03066869 Phase 4
33 Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis. Not yet recruiting NCT03164473 Phase 4
34 Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation Not yet recruiting NCT03133767 Phase 4
35 Normal Saline Versus Heparinized Solution Flush for Maintaining Patency of Peripheral Venous Catheters in Children Suspended NCT01794767 Phase 4
36 Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels Terminated NCT00578578 Phase 4
37 Anti-Oxidant Therapy In Chronic Renal Insufficiency (ATIC) Study Terminated NCT00384618 Phase 4
38 Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") Terminated NCT00747461 Phase 4
39 Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy Terminated NCT02373397 Phase 4
40 Prolonging the Duration of Peripheral Venous Catheters in Cystic Fibrosis People Terminated NCT00418470 Phase 4
41 WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides Unknown status NCT00349674 Phase 3
42 Mycophenolate Mofetil for Treatment of Relapses of Wegener's Disease or Microscopic Polyangiitis (MPA) Unknown status NCT00103792 Phase 3
43 Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB) Unknown status NCT00167583 Phase 3
44 Pain and Music Therapy in Patients Suffering Arteritis Unknown status NCT01323504 Phase 3
45 Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change Unknown status NCT00103636 Phase 2, Phase 3
46 Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica Unknown status NCT01423591 Phase 3
47 Efficacy and Tolerance of Tocilizumab In Takayasu Arteritis Unknown status NCT02101333 Phase 3
48 Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis Completed NCT00414128 Phase 2, Phase 3
49 Pulse Versus Continuous Cyclophosphamide for Induction of Remission in ANCA-Associated Vasculitides Completed NCT00430105 Phase 2, Phase 3
50 Efficacy Study of Two Treatments in the Remission of Vasculitis Completed NCT00748644 Phase 3

Search NIH Clinical Center for Vasculitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: vasculitis

Genetic Tests for Vasculitis

Genetic tests related to Vasculitis:

id Genetic test Affiliating Genes
1 Vasculitis 29

Anatomical Context for Vasculitis

MalaCards organs/tissues related to Vasculitis:

39
Neutrophil, Endothelial, Lung, T Cells, Heart, Skin, B Cells

Publications for Vasculitis

Articles related to Vasculitis:

(show top 50) (show all 2647)
id Title Authors Year
1
CD4(+)CD28(null) T Cells are related to previous cytomegalovirus infection but not to accelerated atherosclerosis in ANCA-associated vasculitis. ( 28084533 )
2017
2
Decline of cellular activation in non-B cells after rituximab treatment in hepatitis C-associated mixed cryoglobulinemia vasculitis. ( 27666584 )
2017
3
Successful Treatment of Central Nervous System Vasculitis Associated with Relapsing Polychondritis With Cyclophosphamide. ( 28502337 )
2017
4
ANCA vasculitis in a patient with Alport syndrome: a difficult diagnosis but a treatable disease! ( 28356090 )
2017
5
Usual and Unusual Manifestations of Systemic and Central Nervous System Vasculitis. ( 27894445 )
2017
6
Non HCV-related cryoglobulinemic vasculitis and Parvovirus-B19 infection. ( 28062379 )
2017
7
The Effects of Plasma Exchange on Severe Vasculitis with Diffuse Alveolar Hemorrhage. ( 28050000 )
2017
8
Central nervous system vasculitis in adults: An update. ( 28087351 )
2017
9
Epigenetic Modifications in ANCA-Associated Vasculitis: Potential for Insights into Disease Pathogenesis and Prediction of Outcome? ( 28049651 )
2017
10
Erythema induratum (nodular vasculitis) associated with Takayasu arteritis. ( 28470150 )
2017
11
Amyopathic Dermatomyositis Associated with Histopathological Findings of Organizing Pneumonia and Pulmonary Vasculitis. ( 28443580 )
2017
12
Dabigatran-related leukocytoclastic vasculitis. ( 28052946 )
2017
13
RETINAL VASCULITIS ASSOCIATED WITH NEUROMYELITIS OPTICA. ( 27820753 )
2017
14
Tuberculosis mimicking primary systemic vasculitis: not to be missed! ( 28092221 )
2017
15
Incidence of Malignancy Prior to Antineutrophil Cytoplasmic Antibody-associated Vasculitis Compared to the General Population. ( 28089971 )
2017
16
Acute necrotizing retinal vasculitis as onset of systemic lupus erythematosus: A case report. ( 28079801 )
2017
17
Revisiting the systemic vasculitis in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): A study of 157 patients by the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires and the European Respiratory Society Taskforce on eosinophilic granulomatosis with polyangiitis (Churg-Strauss). ( 27671089 )
2017
18
Therapy and prognosis of ANCA-associated vasculitis from the clinical nephrologist's perspective. ( 27671907 )
2017
19
Clinical trials in antineutrophil cytoplasmic antibody-associated vasculitis: what we have learnt so far, and what we still have to learn. ( 28087591 )
2017
20
Paediatric anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: an update on renal management. ( 28062909 )
2017
21
Central nervous system vasculitis in adults and children. ( 27112683 )
2016
22
Serum levels of the soluble haemoglobin scavenger receptor CD163 in MPO-ANCA-associated renal vasculitis. ( 27094919 )
2016
23
Endothelial progenitor cells are differentially impaired in ANCA-associated vasculitis compared to healthy controls. ( 27338585 )
2016
24
Postoperative hemorrhagic occlusive retinal vasculitis associated with intracameral vancomycin prophylaxis duringA cataract surgery. ( 27956296 )
2016
25
A case of refractory eosinophilic fasciitis with eosinophilic vasculitis. ( 27033137 )
2016
26
MICROVASCULAR FLOW ABNORMALITIES ASSOCIATED WITH RETINAL VASCULITIS: A Potential of Mechanism of Retinal Injury. ( 27759582 )
2016
27
Hypertrophic Pachymeningitis With Optic Neuropathy Heralding Systemic Vasculitis. ( 27184909 )
2016
28
Refractory rheumatoid vasculitis-a therapeutic dilemma. ( 28031846 )
2016
29
HLA-DPB1 as a risk factor for relapse in ANCA-associated vasculitis - a cohort study. ( 26866715 )
2016
30
Immunoglobulin A Vasculitis Complicated with Clostridium difficile Infection: a Rare Case Report and Brief Review of the Literature. ( 27308656 )
2016
31
Adaptive Optics Imaging in Retinal Vasculitis. ( 28010147 )
2016
32
Possible intrinsic association of anti-neutrophil cytoplasmic antibody-associated vasculitis coexisting with multiple myeloma. ( 27602144 )
2016
33
Necrotizing arteritis occurring in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome. ( 26874730 )
2016
34
ADULT WITH CHICKENPOX COMPLICATED BY SYSTEMIC VASCULITIS AND BILATERAL RETINAL VASCULITIS WITH RETINAL VASCULAR OCCLUSIONS. ( 27533640 )
2016
35
Epididymitis with Epididymal Cyst Indicating Immunoglobulin A Vasculitis in an AdultAi Nanbu, Kazumitsu Sugiura, Naoto Sassa, Masashi Akiyama. ( 26911283 )
2016
36
A case of rheumatoid vasculitis. ( 27037329 )
2016
37
Induction treatment of previously undiagnosed ANCA-associated vasculitis in a renal transplant patient with Rituximab. ( 27699052 )
2016
38
Neurological manifestations in ANCA-associated vasculitis - assessment and treatment. ( 26967679 )
2016
39
Hepatic and Mesenteric Vasculitis as Presenting Manifestation of Mixed Cryoglobulinemia Related to Chronic Hepatitis C Virus Infection in a Female Patient. ( 27219310 )
2016
40
Failure of pneumococcal immunization during remission induction treatment of ANCA-associated vasculitis: The Pneumovas Pilot 1 study. ( 27825574 )
2016
41
Can a rise in ANCA Titer Predict Relapses in ANCA-Associated Vasculitis? ( 26882278 )
2016
42
Fluorescein Photodiagnosis of Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis (IRVAN) Syndrome: A Case Report and Long-Term Outcome of Photocoagulation Therapy. ( 27491854 )
2016
43
Azathioprine-induced eosinophilic myocarditis in a patient with ANCA-associated vasculitis. ( 26950304 )
2016
44
Leukocytoclastic Vasculitis with Systemic Involvement Associated with Ciprofloxacin Therapy: Case Report and Review of the Literature. ( 28070469 )
2016
45
Cardiac ANCA-associated vasculitis mimicking an acute coronary syndrome. ( 27064642 )
2016
46
Canadian Retina Society ocular safety and therapeutics update: hemorrhagic occlusive retinal vasculitis. ( 27316278 )
2016
47
Vanishing retinal arterial aneurysms with anti-tubercular treatment in a patient presenting with idiopathic retinal vasculitis, aneurysms, and neuroretinitis. ( 26922651 )
2016
48
Overview of the Pathogenesis of ANCA-Associated Vasculitis. ( 27536680 )
2016
49
Antineutrophil Cytoplasmic Antibody-associated Vasculitis Superimposed on Infection-related Glomerulonephritis Secondary to Pulmonary Mycobacterium avium Complex Infection. ( 27580547 )
2016
50
End-stage renal disease in ANCA-associated vasculitis. ( 27190338 )
2016

Variations for Vasculitis

Expression for Vasculitis

Search GEO for disease gene expression data for Vasculitis.

Pathways for Vasculitis

Pathways related to Vasculitis according to GeneCards Suite gene sharing:

(show all 19)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.15 BPI CD40LG CD79A CRP CTSG ELANE
2 12.47 CD40LG CD79A MPO TNF TNFSF13B VCAM1
3
Show member pathways
12.28 BPI CTSG ELANE PRTN3 S100A9
4
Show member pathways
12.19 CRP ICAM1 MPO TNF
5 12.02 ICAM1 SELE THBD TNF VCAM1
6 12 CD40LG ICAM1 SELE VCAM1
7 11.86 ICAM1 SELE TNF VCAM1
8 11.8 ICAM1 SELE THBD TNF VCAM1
9 11.74 CD40LG ICAM1 TNF TNFSF13B VCAM1
10
Show member pathways
11.69 CD40LG TNF TNFSF13B
11 11.64 ELANE MPO PRTN3
12
Show member pathways
11.61 CD40LG TNF TNFSF13B
13 11.56 CD40LG ICAM1 TNF TNFSF13B VCAM1
14
Show member pathways
11.45 CD40LG ICAM1 SELE TNF VCAM1
15 11.44 ELANE ICAM1 MPO TNF
16 11.38 ICAM1 SELE VCAM1
17 11.28 ICAM1 SELE TNF VCAM1
18 11.04 CD40LG ICAM1 SELE TNF VCAM1
19 10.66 ICAM1 MPO TNF VCAM1

GO Terms for Vasculitis

Cellular components related to Vasculitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.8 APOH CTSG PRTN3 S100A9 VWF
2 extracellular region GO:0005576 9.8 APOH BPI CD40LG CRP CTSG ELANE
3 external side of plasma membrane GO:0009897 9.77 CD40LG CD79A ICAM1 TNF VCAM1
4 cell surface GO:0009986 9.76 APOH CD40LG CTSG ELANE ICAM1 THBD
5 membrane raft GO:0045121 9.73 CD79A ICAM1 SELE TNF
6 azurophil granule lumen GO:0035578 9.65 BPI CTSG ELANE MPO PRTN3
7 secretory granule GO:0030141 9.63 CTSG ELANE MPO
8 extracellular space GO:0005615 9.55 APOH BPI CD40LG CRP CTSG ELANE
9 extracellular exosome GO:0070062 10.13 APOH BPI CRP CTSG ELANE ICAM1

Biological processes related to Vasculitis according to GeneCards Suite gene sharing:

(show all 32)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.95 CD40LG CRP MEFV S100A9 SELE TNF
2 extracellular matrix organization GO:0030198 9.92 ICAM1 TNF VCAM1 VWF
3 regulation of immune response GO:0050776 9.92 CD40LG ICAM1 TNFSF13B VCAM1
4 blood coagulation GO:0007596 9.9 PRTN3 SERPINA1 THBD VWF
5 leukocyte migration GO:0050900 9.89 ELANE ICAM1 SELE THBD TNF
6 defense response to bacterium GO:0042742 9.88 BPI CTSG ELANE MPO S100A9 TNF
7 neutrophil degranulation GO:0043312 9.86 BPI CTSG ELANE MPO PRTN3 S100A9
8 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.83 CD40LG ICAM1 S100A9 TNF
9 defense response to Gram-positive bacterium GO:0050830 9.81 CRP CTSG TNF
10 B cell differentiation GO:0030183 9.81 CD40LG CD79A VCAM1
11 positive regulation of T cell proliferation GO:0042102 9.79 CD40LG TNFSF13B VCAM1
12 hemostasis GO:0007599 9.75 SERPINA1 THBD VWF
13 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.74 ICAM1 SELE VCAM1
14 defense response to fungus GO:0050832 9.67 CTSG ELANE MPO S100A9
15 negative regulation of blood coagulation GO:0030195 9.65 APOH THBD
16 positive regulation of immune response GO:0050778 9.65 CTSG ELANE
17 negative regulation of fibrinolysis GO:0051918 9.64 APOH THBD
18 negative regulation of lipid storage GO:0010888 9.63 CRP TNF
19 leukocyte tethering or rolling GO:0050901 9.63 SELE TNF VCAM1
20 leukocyte cell-cell adhesion GO:0007159 9.62 CD40LG ICAM1 SELE VCAM1
21 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.61 ELANE TNF
22 leukocyte migration involved in inflammatory response GO:0002523 9.61 ELANE S100A9 SELE
23 response to yeast GO:0001878 9.59 ELANE MPO
24 acute inflammatory response to antigenic stimulus GO:0002438 9.58 ELANE ICAM1
25 membrane to membrane docking GO:0022614 9.56 ICAM1 VCAM1
26 immunoglobulin secretion GO:0048305 9.55 CD40LG TNFSF13B
27 antimicrobial humoral response GO:0019730 9.55 BPI CTSG ELANE PRTN3 S100A9
28 regulation of immunoglobulin secretion GO:0051023 9.54 CD40LG TNF
29 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.51 ICAM1 TNF
30 negative regulation of growth of symbiont in host GO:0044130 9.26 CTSG ELANE MPO TNF
31 response to lipopolysaccharide GO:0032496 9.17 CTSG ELANE ICAM1 MPO SELE THBD
32 immune response GO:0006955 10.05 BPI CD40LG CTSG TNF TNFSF13B

Molecular functions related to Vasculitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 9.46 APOH CTSG ELANE MPO
2 glycoprotein binding GO:0001948 9.43 APOH SERPINA1 VWF
3 tumor necrosis factor receptor binding GO:0005164 9.13 CD40LG TNF TNFSF13B
4 protease binding GO:0002020 8.92 ELANE SERPINA1 TNF VWF

Sources for Vasculitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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37 KEGG
38 LifeMap
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42 MeSH
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59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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