MCID: VSM001
MIFTS: 53

Vasomotor Rhinitis malady

Respiratory diseases category
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Summaries for Vasomotor Rhinitis

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8Disease Ontology, 33MalaCards
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Disease Ontology:8 A rhinitis which involves a hypersensitive reaction to various potentially irritating stimuli such as changes in weather, temperature, or barometric pressure, chemical irritants such as smoke, ozone, pollution, perfumes, and aerosol sprays, psychological stress and emotional shocks, medications, alcohol, and spicy food.

MalaCards: Vasomotor Rhinitis, also known as rhinitis, vasomotor, is related to rhinitis and asthma. An important gene associated with Vasomotor Rhinitis is IL16 (interleukin 16), and among its related pathways are Cytokines and Inflammatory Response and OX40 Pathway. The drugs ipratropium and ipratropium bromide and the compounds rp67580 and gr 73632 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are endocrine/exocrine gland and respiratory system.

Aliases & Classifications for Vasomotor Rhinitis

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8Disease Ontology, 45Novoseek, 62UMLS, 58SNOMED-CT, 40NCIt, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

vasomotor rhinitis 8
rhinitis, vasomotor 62
rhinitis vasomotor 45


External Ids:

Disease Ontology8 DOID:4730
NCIt40 C34988
MeSH35 D012223
ICD1025 J30.0

Related Diseases for Vasomotor Rhinitis

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17GeneCards, 18GeneDecks
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Diseases related to Vasomotor Rhinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1rhinitis32.0TAC1, IL13, VIP
2asthma30.8TAC1, IL13, IL10, IL16, VIP
3allergic rhinitis30.6TAC1, IL13, IL10, IL16, VIP
4atopy30.2IL16, IL10, IL13
5blindness10.5
6autonomic dysfunction10.3
7petrositis10.2
8neuronitis10.2
9hyperinsulinism10.2
10atrophic rhinitis10.2
11hypertension10.2
12paine syndrome10.2
13sinusitis10.2
14endolymphatic hydrops10.2
15vipoma10.1VIP
16filariasis10.1IL13
17constipation10.1VIP, TAC1
18bronchitis10.1VIP, TAC1
19hirschsprung's disease10.1VIP, TAC1
20complex regional pain syndrome10.0TAC1, CALCA
21respiratory failure10.0IL13, TAC1
22wdha syndrome10.0CALCA, VIP
23cutaneous leishmaniasis10.0IL10, IL13
24cluster headache10.0VIP, CALCA
25pancreatic islet cell tumors10.0CALCA, VIP
26somatostatinoma10.0VIP, CALCA
27periodontitis10.0IL10, IL16
28leishmaniasis10.0IL10, IL13
29neuroendocrine tumor10.0CALCA, VIP
30pain agnosia10.0CALCA, TAC1
31multiple endocrine neoplasia10.0VIP, CALCA
32inflammatory bowel disease10.0IL10, TAC1
33graft versus host disease10.0IL13, IL10
34dermatitis10.0TAC1, IL13, IL16
35pulmonary disease, chronic obstructive10.0TAC1, IL13, IL16
36selective iga deficiency disease10.0CD40LG, IL10
37pre-eclampsia10.0TAC1, IL10, IL16
38septic shock10.0IL10, VIP
39pancreatitis10.0IL10, TAC1
40diarrhea10.0VIP, CALCA, TAC1
41common variable immune deficiency10.0IL10, CD40LG
42migraine10.0TAC1, CALCA, VIP
43eosinophilia10.0IL13, IL10, IL16
44carcinoid syndrome10.0TAC1, CALCA, VIP
45cholera10.0VIP, CALCA, TAC1
46cork-handlers' disease10.0IL16, IL10, IL13
47insulinoma10.0CALCA, VIP
48pneumonia10.0IL13, IL10, IL16
49lung small cell carcinoma10.0TAC1, CALCA, VIP
50osteoarthritis10.0TAC1, CALCA, IL16

Graphical network of the top 20 diseases related to Vasomotor Rhinitis:



Diseases related to vasomotor rhinitis

Symptoms for Vasomotor Rhinitis

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Drugs & Therapeutics for Vasomotor Rhinitis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Genetic Tests for Vasomotor Rhinitis

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Anatomical Context for Vasomotor Rhinitis

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33MalaCards
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MalaCards organs/tissues related to Vasomotor Rhinitis:

33
Heart

Animal Models for Vasomotor Rhinitis or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Vasomotor Rhinitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5CD40LG, IL13, IL10, VIP
2MP:00053888.5VIP, IL10, IL13, CALCA
3MP:00107718.0CD40LG, TAC1, CALCA, IL13, IL10
4MP:00053858.0VIP, IL10, CALCA, TAC1, CD40LG
5MP:00053877.9VIP, IL16, IL10, IL13, CD40LG

Publications for Vasomotor Rhinitis

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Sources:
52PubMed
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Articles related to Vasomotor Rhinitis:

(show top 50)    (show all 191)
idTitleAuthorsYear
1
Cytologic alterations in nasal mucosa after sphenopalatine artery ligation in patients with vasomotor rhinitis. (22391083)
2012
2
Severe unilateral vasomotor rhinitis: an antecedent sign of vascular compromise? (22672492)
2012
3
Sphenopalatine artery ligation with nerve resection in patients with vasomotor rhinitis and polyposis: a prospective, randomized, double-blind investigation. (22339556)
2012
4
Vasomotor rhinitis. (20425499)
2010
5
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy Part 1. Introduction. (24229340)
2009
6
Weather/temperature-sensitive vasomotor rhinitis may be refractory to intranasal corticosteroid treatment. (19463202)
2009
7
Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis. (18446592)
2008
8
Autonomic nervous system evaluation using heart rate variability parameters in vasomotor rhinitis patients. (17049152)
2006
9
Nasal wall compliance in vasomotor rhinitis. (16141379)
2006
10
Vasomotor rhinitis. (16190503)
2005
11
Immunohistochemical localization of 3-nitrotyrosine in the nasal respiratory mucosa of patients with vasomotor rhinitis. (15799577)
2005
12
Ultrastructural and ultracytochemical study of the human nasal respiratory epithelium in vasomotor rhinitis. (14606598)
2003
13
Autonomic nervous system evaluation of patients with vasomotor rhinitis. (11081594)
2000
14
Allergic and vasomotor rhinitis in asthmatics in the tropics and subtropics. (2360127)
1990
15
Vasomotor rhinitis with headshaking in a pony. (2361515)
1990
16
The effect of ipratropium bromide on nasal hypersecretion induced by methacholine in patients with vasomotor rhinitis. A double-blind, cross-over, placebo-controlled and randomized dose-response study. (2974675)
1988
17
Vasomotor rhinitis. (3111614)
1987
18
Nasal disorders in children. Allergic rhinitis, vasomotor rhinitis, and nasal polyps. (3588472)
1987
19
The use of intranasal Atrovent in the treatment of vasomotor rhinitis. (2961291)
1987
20
Vasomotor rhinitis. A review and management by intranasal cryotherapy. (4088111)
1985
21
Cryotherapy for chronic vasomotor rhinitis: technique and patient selection for improved results. (6708699)
1984
22
Cryosurgery on postganglionic fibers (posterior nasal branches) of the pterygopalatine ganglion for vasomotor rhinitis. (6613543)
1983
23
Ipratropium (Atrovent) in the treatment of vasomotor rhinitis of elderly patients. (6228347)
1983
24
Vasomotor rhinitis: neglected cause of nasal congestion. (6153128)
1980
25
A comparison of cryosurgery and submucous diathermy in vasomotor rhinitis. (7441052)
1980
26
Vasomotor rhinitis and nasal dyspnea. (862543)
1977
27
Double-blind comparison of metizoline hydrochloride (Ellsyl) and phenylephrine in allergic and vasomotor rhinitis. (49255)
1975
28
Vidian neurectomy in vasomotor rhinitis. (4771966)
1973
29
An antihistamine-sympathomimetic amine combination in vasomotor rhinitis. (4147011)
1973
30
A surgical approach to intractable vasomotor rhinitis. (5086892)
1972
31
A placebo-controlled trial of imipramine in nonspecific vasomotor rhinitis. (4561390)
1972
32
Treatment of vasomotor rhinitis with a combined antihistaminic--sympathomimetic preparation. (4402059)
1971
33
Rhinological methods for controlling nasal polyposis and vasomotor rhinitis. (5862571)
1965
34
Interrelation of asthma and vasomotor rhinitis, occurring in patients with housedust atopy. III. In respect to the localization of the symptoms. (13926727)
1962
35
Drug therapy of vasomotor rhinitis and asthma: dibenzheptropine, a valuable adjuvant in the corticoid treatment. (13926728)
1962
36
Interrelation of vasomotor rhinitis and asthma, occurring in patients with housedustatopy. 2. Influence of houses lived in. (13841298)
1960
37
Reflective reactions of the nasal mucosa in vasomotor rhinitis. (13434903)
1957
38
Vasomotor rhinitis in hypertension. (13296500)
1956
39
Vasomotor rhinitis. (14388570)
1955
40
Some rhinological syndromes and vasomotor rhinitis. (13311963)
1955
41
Results of treatment of vasomotor rhinitis with hyposensitization. (14397980)
1955
42
Vasomotor rhinitis and bronchial asthma due to Locust Bean Gum dust. (13148984)
1954
43
The vasomotor rhinitis syndrome. (13049699)
1953
44
Chronic vasomotor rhinitis; treatment by submucous diathermic coagulation. (13039666)
1953
45
Vasomotor rhinitis. (14846105)
1950
46
The management of vasomotor rhinitis. (18894292)
1948
47
Vasomotor rhinitis and homeopathic treatment. (18890883)
1948
48
Perennial vasomotor rhinitis; a modern approach to diagnosis and treatment. (20278786)
1947
49
Vasomotor Rhinitis. (20323413)
1945
50
Vasomotor rhinitis. (21011217)
1945

Variations for Vasomotor Rhinitis

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Expression for genes affiliated with Vasomotor Rhinitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vasomotor Rhinitis

Search GEO for disease gene expression data for Vasomotor Rhinitis.

Pathways for genes affiliated with Vasomotor Rhinitis

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Sources:
50PathCards, 38NCBI BioSystems Database, 53QIAGEN, 30KEGG, 55Reactome
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Pathways related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4IL13, IL10
29.4IL13, IL10
39.3IL10, CD40LG
49.3CD40LG, IL10
59.1IL13, IL10, IL16
6
Show member pathways
8.9IL10, IL13, CD40LG
7
Show member pathways
8.9IL10, IL13, CD40LG
88.9TAC1, IL13, IL10
9
Show member pathways
8.9CD40LG, CALCA, IL10
10
Show member pathways
8.6CD40LG, IL13, IL10, IL16

Compounds for genes affiliated with Vasomotor Rhinitis

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Sources:
45Novoseek, 29IUPHAR, 61Tocris Bioscience, 11DrugBank, 3BitterDB, 51PharmGKB, 24HMDB
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Compounds related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 132)
idCompoundScoreTop Affiliating Genes
1rp6758045 2910.8TAC1, CALCA
2gr 7363245 6110.7CALCA, TAC1
3ltd4459.6TAC1, IL13, VIP
4helospectin459.6TAC1, CALCA, VIP
5guanethidine45 1110.6VIP, CALCA, TAC1
6cromakalim45 2910.5CALCA, VIP, TAC1
7thiorphan45 29 1111.5VIP, CALCA, TAC1
8ng-nitro-l-arginine459.5VIP, TAC1, CALCA
9erythromycin45 3 51 1112.5VIP, IL13, CD40LG
10resiniferatoxin45 2910.5CALCA, TAC1
11phosphoramidon45 1110.5VIP, CALCA, TAC1
12captopril45 61 51 29 1113.5CALCA, TAC1, VIP
13capsaicin45 2910.4VIP, TAC1, CALCA
14salbutamol45 51 29 24 1113.4IL13, IL10, VIP
15prostaglandin f2alpha459.4TAC1, VIP, CALCA
16atropine45 29 1111.4VIP, CALCA, TAC1
17tetrodotoxin45 61 2911.4TAC1, VIP, CALCA
18glucuronoxylomannan459.4CD40LG, IL10
19propranolol45 29 51 24 1113.4TAC1, CALCA, VIP
20enalapril45 51 1111.3VIP, IL10, TAC1
21praziquantel45 1110.3CD40LG, IL10, IL13
22il-12459.3IL10, IL13, CD40LG
23spantide459.3TAC1, VIP
24allergens459.2IL10, CD40LG, IL13
25rituximab45 51 1111.2CD40LG, IL13, IL10
26corticosterone45 61 2411.2IL10, CALCA, VIP
27sodium nitroprusside459.2TAC1, IL13, VIP
28methacholine45 51 1111.2TAC1, VIP, IL13, CALCA
29thalidomide45 51 61 1112.1CD40LG, IL13, IL10
30isoproterenol45 1110.1VIP, IL13, TAC1, CALCA
31epinephrine45 24 1111.0TAC1, VIP, CD40LG, CALCA
32norepinephrine45 24 1110.9CD40LG, TAC1, VIP, CALCA
33lactate458.9CD40LG, CALCA, IL13, VIP
34dopamine45 29 24 1111.7VIP, CALCA, CD40LG, TAC1
35rantes458.6IL16, CD40LG, VIP, IL13, IL10
36indomethacin45 29 61 1111.6CD40LG, VIP, IL13, CALCA, TAC1
37thymidine45 249.6IL16, IL10, VIP, IL13
38acetylcholine45 51 29 24 1112.6IL13, VIP, CALCA, TAC1, CD40LG
39adenylate458.6VIP, CD40LG, TAC1, CALCA, IL13
40glutamate458.5CD40LG, TAC1, CALCA, IL13, VIP
41thyroxine45 249.5IL10, CALCA, CD40LG, VIP, IL13
42cyclosporin a45 29 6110.5IL10, IL13, CALCA, CD40LG, VIP
43theophylline45 29 24 1111.5IL10, IL16, TAC1, IL13, CD40LG
44estrogen458.5VIP, IL13, CALCA, TAC1, CD40LG
45aspartate458.4VIP, IL10, IL13, TAC1, CD40LG
46vegf458.2CD40LG, CALCA, IL16, VIP, IL13, IL10
47nitric oxide45 24 1110.2IL10, IL16, VIP, IL13, CALCA, TAC1
48dexamethasone45 51 29 1111.1IL10, VIP, IL13, TAC1, CD40LG, IL16
49pge2458.0VIP, IL13, CD40LG, CALCA, TAC1, IL10
50histamine45 29 249.7TAC1, CD40LG, CALCA, IL13, IL10, IL16

GO Terms for genes affiliated with Vasomotor Rhinitis

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16Gene Ontology
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Cellular components related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:0430258.8VIP, CALCA, TAC1
2extracellular regionGO:0055768.7TAC1, CALCA, IL13, VIP
3extracellular spaceGO:0056157.5CD40LG, TAC1, CALCA, IL13, IL10, IL16

Biological processes related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1leukocyte chemotaxisGO:0305959.7IL10, IL16
2positive regulation of vasodilationGO:0459099.7CALCA, VIP
3positive regulation of ossificationGO:0457789.7TAC1, CALCA
4response to painGO:0482659.7TAC1, CALCA
5regulation of sensory perception of painGO:0519309.6VIP, IL10
6leukocyte cell-cell adhesionGO:0071599.6CD40LG, CALCA
7regulation of blood pressureGO:0082179.4CALCA, TAC1
8B cell proliferationGO:0421009.3CD40LG, IL10
9B cell differentiationGO:0301839.0CD40LG, IL10
10negative regulation of apoptotic processGO:0430669.0CD40LG, IL10, VIP
11cell-cell signalingGO:0072678.7IL10, IL13, CALCA, TAC1
12inflammatory responseGO:0069548.2CD40LG, TAC1, CALCA, IL13, IL10

Molecular functions related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.6CALCA, VIP
2cytokine activityGO:0051258.3CD40LG, IL13, IL10, IL16

Products for genes affiliated with Vasomotor Rhinitis

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  • Antibodies
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Sources for Vasomotor Rhinitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet