MCID: VSM001
MIFTS: 53

Vasomotor Rhinitis malady

Respiratory diseases category

Summaries for Vasomotor Rhinitis

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9Disease Ontology, 34MalaCards
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Disease Ontology:9 A rhinitis which involves a hypersensitive reaction to various potentially irritating stimuli such as changes in weather, temperature, or barometric pressure, chemical irritants such as smoke, ozone, pollution, perfumes, and aerosol sprays, psychological stress and emotional shocks, medications, alcohol, and spicy food.

MalaCards: Vasomotor Rhinitis, also known as rhinitis, vasomotor, is related to rhinitis and asthma. An important gene associated with Vasomotor Rhinitis is IL16 (interleukin 16), and among its related pathways are Cytokines and Inflammatory Response and OX40 Pathway. The drugs ipratropium and ipratropium bromide and the compounds rp67580 and gr 73632 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are endocrine/exocrine gland and respiratory system.

Aliases & Classifications for Vasomotor Rhinitis

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9Disease Ontology, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

vasomotor rhinitis 9
rhinitis, vasomotor 63
rhinitis vasomotor 46


External Ids:

Disease Ontology9 DOID:4730
NCIt41 C34988
MeSH36 D012223
ICD1026 J30.0

Related Diseases for Vasomotor Rhinitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Vasomotor Rhinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1rhinitis32.0TAC1, IL13, VIP
2asthma30.8TAC1, IL13, IL10, IL16, VIP
3allergic rhinitis30.6TAC1, IL13, IL10, IL16, VIP
4atopy30.2IL16, IL10, IL13
5blindness10.5
6autonomic dysfunction10.3
7petrositis10.2
8neuronitis10.2
9hyperinsulinism10.2
10atrophic rhinitis10.2
11hypertension10.2
12paine syndrome10.2
13sinusitis10.2
14endolymphatic hydrops10.2
15vipoma10.1VIP
16filariasis10.1IL13
17constipation10.1VIP, TAC1
18bronchitis10.1VIP, TAC1
19hirschsprung's disease10.1VIP, TAC1
20complex regional pain syndrome10.0TAC1, CALCA
21respiratory failure10.0IL13, TAC1
22wdha syndrome10.0CALCA, VIP
23cutaneous leishmaniasis10.0IL10, IL13
24cluster headache10.0VIP, CALCA
25pancreatic islet cell tumors10.0CALCA, VIP
26somatostatinoma10.0VIP, CALCA
27periodontitis10.0IL10, IL16
28leishmaniasis10.0IL10, IL13
29neuroendocrine tumor10.0CALCA, VIP
30pain agnosia10.0CALCA, TAC1
31multiple endocrine neoplasia10.0VIP, CALCA
32inflammatory bowel disease10.0IL10, TAC1
33graft versus host disease10.0IL13, IL10
34dermatitis10.0TAC1, IL13, IL16
35pulmonary disease, chronic obstructive10.0TAC1, IL13, IL16
36selective iga deficiency disease10.0CD40LG, IL10
37pre-eclampsia10.0TAC1, IL10, IL16
38septic shock10.0IL10, VIP
39pancreatitis10.0IL10, TAC1
40diarrhea10.0VIP, CALCA, TAC1
41common variable immune deficiency10.0IL10, CD40LG
42migraine10.0TAC1, CALCA, VIP
43eosinophilia10.0IL13, IL10, IL16
44carcinoid syndrome10.0TAC1, CALCA, VIP
45cholera10.0VIP, CALCA, TAC1
46cork-handlers' disease10.0IL16, IL10, IL13
47insulinoma10.0CALCA, VIP
48pneumonia10.0IL13, IL10, IL16
49lung small cell carcinoma10.0TAC1, CALCA, VIP
50osteoarthritis10.0TAC1, CALCA, IL16

Graphical network of the top 20 diseases related to Vasomotor Rhinitis:



Diseases related to vasomotor rhinitis

Symptoms for Vasomotor Rhinitis

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Drugs & Therapeutics for Vasomotor Rhinitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Genetic Tests for Vasomotor Rhinitis

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Anatomical Context for Vasomotor Rhinitis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Vasomotor Rhinitis:

34
Heart

Animal Models for Vasomotor Rhinitis or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Vasomotor Rhinitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5CD40LG, IL13, IL10, VIP
2MP:00053888.5VIP, IL10, IL13, CALCA
3MP:00107718.0CD40LG, TAC1, CALCA, IL13, IL10
4MP:00053858.0VIP, IL10, CALCA, TAC1, CD40LG
5MP:00053877.9VIP, IL16, IL10, IL13, CD40LG

Publications for Vasomotor Rhinitis

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Sources:
53PubMed
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Articles related to Vasomotor Rhinitis:

(show top 50)    (show all 191)
idTitleAuthorsYear
1
Cytologic alterations in nasal mucosa after sphenopalatine artery ligation in patients with vasomotor rhinitis. (22391083)
2012
2
Severe unilateral vasomotor rhinitis: an antecedent sign of vascular compromise? (22672492)
2012
3
Sphenopalatine artery ligation with nerve resection in patients with vasomotor rhinitis and polyposis: a prospective, randomized, double-blind investigation. (22339556)
2012
4
Vasomotor rhinitis. (20425499)
2010
5
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy Part 1. Introduction. (24229340)
2009
6
Weather/temperature-sensitive vasomotor rhinitis may be refractory to intranasal corticosteroid treatment. (19463202)
2009
7
Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis. (18446592)
2008
8
Autonomic nervous system evaluation using heart rate variability parameters in vasomotor rhinitis patients. (17049152)
2006
9
Nasal wall compliance in vasomotor rhinitis. (16141379)
2006
10
Vasomotor rhinitis. (16190503)
2005
11
Immunohistochemical localization of 3-nitrotyrosine in the nasal respiratory mucosa of patients with vasomotor rhinitis. (15799577)
2005
12
Ultrastructural and ultracytochemical study of the human nasal respiratory epithelium in vasomotor rhinitis. (14606598)
2003
13
Autonomic nervous system evaluation of patients with vasomotor rhinitis. (11081594)
2000
14
Allergic and vasomotor rhinitis in asthmatics in the tropics and subtropics. (2360127)
1990
15
Vasomotor rhinitis with headshaking in a pony. (2361515)
1990
16
The effect of ipratropium bromide on nasal hypersecretion induced by methacholine in patients with vasomotor rhinitis. A double-blind, cross-over, placebo-controlled and randomized dose-response study. (2974675)
1988
17
Vasomotor rhinitis. (3111614)
1987
18
Nasal disorders in children. Allergic rhinitis, vasomotor rhinitis, and nasal polyps. (3588472)
1987
19
The use of intranasal Atrovent in the treatment of vasomotor rhinitis. (2961291)
1987
20
Vasomotor rhinitis. A review and management by intranasal cryotherapy. (4088111)
1985
21
Cryotherapy for chronic vasomotor rhinitis: technique and patient selection for improved results. (6708699)
1984
22
Cryosurgery on postganglionic fibers (posterior nasal branches) of the pterygopalatine ganglion for vasomotor rhinitis. (6613543)
1983
23
Ipratropium (Atrovent) in the treatment of vasomotor rhinitis of elderly patients. (6228347)
1983
24
Vasomotor rhinitis: neglected cause of nasal congestion. (6153128)
1980
25
A comparison of cryosurgery and submucous diathermy in vasomotor rhinitis. (7441052)
1980
26
Vasomotor rhinitis and nasal dyspnea. (862543)
1977
27
Double-blind comparison of metizoline hydrochloride (Ellsyl) and phenylephrine in allergic and vasomotor rhinitis. (49255)
1975
28
Vidian neurectomy in vasomotor rhinitis. (4771966)
1973
29
An antihistamine-sympathomimetic amine combination in vasomotor rhinitis. (4147011)
1973
30
A surgical approach to intractable vasomotor rhinitis. (5086892)
1972
31
A placebo-controlled trial of imipramine in nonspecific vasomotor rhinitis. (4561390)
1972
32
Treatment of vasomotor rhinitis with a combined antihistaminic--sympathomimetic preparation. (4402059)
1971
33
Rhinological methods for controlling nasal polyposis and vasomotor rhinitis. (5862571)
1965
34
Interrelation of asthma and vasomotor rhinitis, occurring in patients with housedust atopy. III. In respect to the localization of the symptoms. (13926727)
1962
35
Drug therapy of vasomotor rhinitis and asthma: dibenzheptropine, a valuable adjuvant in the corticoid treatment. (13926728)
1962
36
Interrelation of vasomotor rhinitis and asthma, occurring in patients with housedustatopy. 2. Influence of houses lived in. (13841298)
1960
37
Reflective reactions of the nasal mucosa in vasomotor rhinitis. (13434903)
1957
38
Vasomotor rhinitis in hypertension. (13296500)
1956
39
Vasomotor rhinitis. (14388570)
1955
40
Some rhinological syndromes and vasomotor rhinitis. (13311963)
1955
41
Results of treatment of vasomotor rhinitis with hyposensitization. (14397980)
1955
42
Vasomotor rhinitis and bronchial asthma due to Locust Bean Gum dust. (13148984)
1954
43
The vasomotor rhinitis syndrome. (13049699)
1953
44
Chronic vasomotor rhinitis; treatment by submucous diathermic coagulation. (13039666)
1953
45
Vasomotor rhinitis. (14846105)
1950
46
The management of vasomotor rhinitis. (18894292)
1948
47
Vasomotor rhinitis and homeopathic treatment. (18890883)
1948
48
Perennial vasomotor rhinitis; a modern approach to diagnosis and treatment. (20278786)
1947
49
Vasomotor Rhinitis. (20323413)
1945
50
Vasomotor rhinitis. (21011217)
1945

Variations for Vasomotor Rhinitis

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Expression for genes affiliated with Vasomotor Rhinitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vasomotor Rhinitis

Search GEO for disease gene expression data for Vasomotor Rhinitis.

Pathways for genes affiliated with Vasomotor Rhinitis

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Sources:
51PathCards, 39NCBI BioSystems Database, 54QIAGEN, 31KEGG, 56Reactome
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Pathways related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4IL13, IL10
29.4IL13, IL10
39.3IL10, CD40LG
49.3CD40LG, IL10
59.1IL13, IL10, IL16
6
Show member pathways
8.9IL10, IL13, CD40LG
7
Show member pathways
8.9IL10, IL13, CD40LG
88.9TAC1, IL13, IL10
9
Show member pathways
8.9CD40LG, CALCA, IL10
10
Show member pathways
8.6CD40LG, IL13, IL10, IL16

Compounds for genes affiliated with Vasomotor Rhinitis

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Sources:
46Novoseek, 30IUPHAR, 62Tocris Bioscience, 12DrugBank, 3BitterDB, 52PharmGKB, 25HMDB
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Compounds related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 132)
idCompoundScoreTop Affiliating Genes
1rp6758046 3010.8TAC1, CALCA
2gr 7363246 6210.7CALCA, TAC1
3ltd4469.6TAC1, IL13, VIP
4helospectin469.6TAC1, CALCA, VIP
5guanethidine46 1210.6VIP, CALCA, TAC1
6cromakalim46 3010.5CALCA, VIP, TAC1
7thiorphan46 30 1211.5VIP, CALCA, TAC1
8ng-nitro-l-arginine469.5VIP, TAC1, CALCA
9erythromycin46 3 52 1212.5VIP, IL13, CD40LG
10resiniferatoxin46 3010.5CALCA, TAC1
11phosphoramidon46 1210.5VIP, CALCA, TAC1
12captopril46 62 52 30 1213.5CALCA, TAC1, VIP
13capsaicin46 3010.4VIP, TAC1, CALCA
14salbutamol46 52 30 25 1213.4IL13, IL10, VIP
15prostaglandin f2alpha469.4TAC1, VIP, CALCA
16atropine46 30 1211.4VIP, CALCA, TAC1
17tetrodotoxin46 62 3011.4TAC1, VIP, CALCA
18glucuronoxylomannan469.4CD40LG, IL10
19propranolol46 30 52 25 1213.4TAC1, CALCA, VIP
20enalapril46 52 1211.3VIP, IL10, TAC1
21praziquantel46 1210.3CD40LG, IL10, IL13
22il-12469.3IL10, IL13, CD40LG
23spantide469.3TAC1, VIP
24allergens469.2IL10, CD40LG, IL13
25rituximab46 52 1211.2CD40LG, IL13, IL10
26corticosterone46 62 2511.2IL10, CALCA, VIP
27sodium nitroprusside469.2TAC1, IL13, VIP
28methacholine46 52 1211.2TAC1, VIP, IL13, CALCA
29thalidomide46 52 62 1212.1CD40LG, IL13, IL10
30isoproterenol46 1210.1VIP, IL13, TAC1, CALCA
31epinephrine46 25 1211.0TAC1, VIP, CD40LG, CALCA
32norepinephrine46 25 1210.9CD40LG, TAC1, VIP, CALCA
33lactate468.9CD40LG, CALCA, IL13, VIP
34dopamine46 30 25 1211.7VIP, CALCA, CD40LG, TAC1
35rantes468.6IL16, CD40LG, VIP, IL13, IL10
36indomethacin46 30 62 1211.6CD40LG, VIP, IL13, CALCA, TAC1
37thymidine46 259.6IL16, IL10, VIP, IL13
38acetylcholine46 52 30 25 1212.6IL13, VIP, CALCA, TAC1, CD40LG
39adenylate468.6VIP, CD40LG, TAC1, CALCA, IL13
40glutamate468.5CD40LG, TAC1, CALCA, IL13, VIP
41thyroxine46 259.5IL10, CALCA, CD40LG, VIP, IL13
42cyclosporin a46 30 6210.5IL10, IL13, CALCA, CD40LG, VIP
43theophylline46 30 25 1211.5IL10, IL16, TAC1, IL13, CD40LG
44estrogen468.5VIP, IL13, CALCA, TAC1, CD40LG
45aspartate468.4VIP, IL10, IL13, TAC1, CD40LG
46vegf468.2CD40LG, CALCA, IL16, VIP, IL13, IL10
47nitric oxide46 25 1210.2IL10, IL16, VIP, IL13, CALCA, TAC1
48dexamethasone46 52 30 1211.1IL10, VIP, IL13, TAC1, CD40LG, IL16
49pge2468.0VIP, IL13, CD40LG, CALCA, TAC1, IL10
50histamine46 30 259.7TAC1, CD40LG, CALCA, IL13, IL10, IL16

GO Terms for genes affiliated with Vasomotor Rhinitis

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17Gene Ontology
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Cellular components related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:0430258.8VIP, CALCA, TAC1
2extracellular regionGO:0055768.7TAC1, CALCA, IL13, VIP
3extracellular spaceGO:0056157.5CD40LG, TAC1, CALCA, IL13, IL10, IL16

Biological processes related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1leukocyte chemotaxisGO:0305959.7IL10, IL16
2positive regulation of vasodilationGO:0459099.7CALCA, VIP
3positive regulation of ossificationGO:0457789.7TAC1, CALCA
4response to painGO:0482659.7TAC1, CALCA
5regulation of sensory perception of painGO:0519309.6VIP, IL10
6leukocyte cell-cell adhesionGO:0071599.6CD40LG, CALCA
7regulation of blood pressureGO:0082179.4CALCA, TAC1
8B cell proliferationGO:0421009.3CD40LG, IL10
9B cell differentiationGO:0301839.0CD40LG, IL10
10negative regulation of apoptotic processGO:0430669.0CD40LG, IL10, VIP
11cell-cell signalingGO:0072678.7IL10, IL13, CALCA, TAC1
12inflammatory responseGO:0069548.2CD40LG, TAC1, CALCA, IL13, IL10

Molecular functions related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.6CALCA, VIP
2cytokine activityGO:0051258.3CD40LG, IL13, IL10, IL16

Products for genes affiliated with Vasomotor Rhinitis

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  • Antibodies
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Sources for Vasomotor Rhinitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet