MCID: VSM001
MIFTS: 54

Vasomotor Rhinitis malady

Respiratory diseases category
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Summaries for Vasomotor Rhinitis

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Disease Ontology:8 A rhinitis which involves a hypersensitive reaction to various potentially irritating stimuli such as changes in weather, temperature, or barometric pressure, chemical irritants such as smoke, ozone, pollution, perfumes, and aerosol sprays, psychological stress and emotional shocks, medications, alcohol, and spicy food.

MalaCards based summary: Vasomotor Rhinitis, also known as rhinitis, vasomotor, is related to rhinitis and asthma. An important gene associated with Vasomotor Rhinitis is IL16 (interleukin 16), and among its related pathways are Cytokines and Inflammatory Response and OX40 Pathway. The drugs brompheniramine and phenylpropanolamine hydrochloride and the compounds rp67580 and gr 73632 have been mentioned in the context of this disorder. Affiliated tissues include heart, and related mouse phenotypes are endocrine/exocrine gland and respiratory system.

Aliases & Classifications for Vasomotor Rhinitis

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
See all sources

Vasomotor Rhinitis, Aliases & Descriptions:

Name: Vasomotor Rhinitis 8
Rhinitis, Vasomotor 62
 
Rhinitis Vasomotor 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:4730
NCIt39 C34988
MeSH34 D012223
ICD1025 J30.0

Related Diseases for Vasomotor Rhinitis

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Diseases related to Vasomotor Rhinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1rhinitis32.1TAC1, IL13, VIP
2asthma30.4TAC1, IL13, IL10, IL16, VIP
3allergic rhinitis30.3TAC1, IL13, IL10, IL16, VIP
4atopy30.3IL16, IL10, IL13
5blindness10.5
6vipoma10.4VIP
7filariasis10.4IL13
8autonomic dysfunction10.3
9constipation10.3VIP, TAC1
10bronchitis10.2VIP, TAC1
11hirschsprung's disease10.2VIP, TAC1
12complex regional pain syndrome10.2TAC1, CALCA
13respiratory failure10.2IL13, TAC1
14wdha syndrome10.2CALCA, VIP
15cutaneous leishmaniasis10.2IL10, IL13
16sinusitis10.2
17hyperinsulinism10.2
18atrophic rhinitis10.2
19petrositis10.2
20neuronitis10.2
21endolymphatic hydrops10.2
22cluster headache10.2VIP, CALCA
23pancreatic islet cell tumors10.2CALCA, VIP
24somatostatinoma10.2VIP, CALCA
25periodontitis10.2IL10, IL16
26leishmaniasis10.1IL10, IL13
27neuroendocrine tumor10.1CALCA, VIP
28pain agnosia10.1CALCA, TAC1
29multiple endocrine neoplasia10.1VIP, CALCA
30inflammatory bowel disease10.1IL10, TAC1
31graft versus host disease10.1IL13, IL10
32dermatitis10.1TAC1, IL13, IL16
33chronic obstructive pulmonary disease10.1TAC1, IL13, IL16
34selective iga deficiency disease10.1CD40LG, IL10
35pre-eclampsia10.1TAC1, IL10, IL16
36septic shock10.0IL10, VIP
37pancreatitis10.0IL10, TAC1
38diarrhea10.0VIP, CALCA, TAC1
39common variable immunodeficiency10.0IL10, CD40LG
40migraine10.0TAC1, CALCA, VIP
41eosinophilia10.0IL13, IL10, IL16
42carcinoid syndrome10.0TAC1, CALCA, VIP
43cholera10.0VIP, CALCA, TAC1
44cork-handlers' disease10.0IL16, IL10, IL13
45insulinoma10.0CALCA, VIP
46pneumonia10.0IL13, IL10, IL16
47lung small cell carcinoma10.0TAC1, CALCA, VIP
48osteoarthritis10.0TAC1, CALCA, IL16
49lupus nephritis10.0CD40LG, IL10
50multiple sclerosis10.0IL13, IL10, IL16

Graphical network of the top 20 diseases related to Vasomotor Rhinitis:



Diseases related to vasomotor rhinitis

Symptoms for Vasomotor Rhinitis

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Drugs & Therapeutics for Vasomotor Rhinitis

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Genetic Tests for Vasomotor Rhinitis

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Anatomical Context for Vasomotor Rhinitis

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MalaCards organs/tissues related to Vasomotor Rhinitis:

32
Heart

Animal Models for Vasomotor Rhinitis or affiliated genes

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MGI Mouse Phenotypes related to Vasomotor Rhinitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5CD40LG, IL13, IL10, VIP
2MP:00053888.5VIP, IL10, IL13, CALCA
3MP:00107718.0CD40LG, TAC1, CALCA, IL13, IL10
4MP:00053858.0VIP, IL10, CALCA, TAC1, CD40LG
5MP:00053877.9VIP, IL16, IL10, IL13, CD40LG

Publications for Vasomotor Rhinitis

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Articles related to Vasomotor Rhinitis:

(show top 50)    (show all 191)
idTitleAuthorsYear
1
Cytologic alterations in nasal mucosa after sphenopalatine artery ligation in patients with vasomotor rhinitis. (22391083)
2012
2
Severe unilateral vasomotor rhinitis: an antecedent sign of vascular compromise? (22672492)
2012
3
Sphenopalatine artery ligation with nerve resection in patients with vasomotor rhinitis and polyposis: a prospective, randomized, double-blind investigation. (22339556)
2012
4
Vasomotor rhinitis. (20425499)
2010
5
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy Part 1. Introduction. (24229340)
2009
6
Weather/temperature-sensitive vasomotor rhinitis may be refractory to intranasal corticosteroid treatment. (19463202)
2009
7
Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis. (18446592)
2008
8
Autonomic nervous system evaluation using heart rate variability parameters in vasomotor rhinitis patients. (17049152)
2006
9
Nasal wall compliance in vasomotor rhinitis. (16141379)
2006
10
Vasomotor rhinitis. (16190503)
2005
11
Immunohistochemical localization of 3-nitrotyrosine in the nasal respiratory mucosa of patients with vasomotor rhinitis. (15799577)
2005
12
Ultrastructural and ultracytochemical study of the human nasal respiratory epithelium in vasomotor rhinitis. (14606598)
2003
13
Autonomic nervous system evaluation of patients with vasomotor rhinitis. (11081594)
2000
14
Allergic and vasomotor rhinitis in asthmatics in the tropics and subtropics. (2360127)
1990
15
Vasomotor rhinitis with headshaking in a pony. (2361515)
1990
16
The effect of ipratropium bromide on nasal hypersecretion induced by methacholine in patients with vasomotor rhinitis. A double-blind, cross-over, placebo-controlled and randomized dose-response study. (2974675)
1988
17
Vasomotor rhinitis. (3111614)
1987
18
Nasal disorders in children. Allergic rhinitis, vasomotor rhinitis, and nasal polyps. (3588472)
1987
19
The use of intranasal Atrovent in the treatment of vasomotor rhinitis. (2961291)
1987
20
Autonomic microganglia of the nasal mucosa and their relation to vasomotor rhinitis. (3780025)
1986
21
Vasomotor rhinitis. A review and management by intranasal cryotherapy. (4088111)
1985
22
Cryotherapy for chronic vasomotor rhinitis: technique and patient selection for improved results. (6708699)
1984
23
Cryosurgery on postganglionic fibers (posterior nasal branches) of the pterygopalatine ganglion for vasomotor rhinitis. (6613543)
1983
24
Ipratropium (Atrovent) in the treatment of vasomotor rhinitis of elderly patients. (6228347)
1983
25
Vasomotor rhinitis: neglected cause of nasal congestion. (6153128)
1980
26
A comparison of cryosurgery and submucous diathermy in vasomotor rhinitis. (7441052)
1980
27
Vasomotor rhinitis and nasal dyspnea. (862543)
1977
28
Double-blind comparison of metizoline hydrochloride (Ellsyl) and phenylephrine in allergic and vasomotor rhinitis. (49255)
1975
29
Vidian neurectomy in vasomotor rhinitis. (4771966)
1973
30
An antihistamine-sympathomimetic amine combination in vasomotor rhinitis. (4147011)
1973
31
A surgical approach to intractable vasomotor rhinitis. (5086892)
1972
32
A placebo-controlled trial of imipramine in nonspecific vasomotor rhinitis. (4561390)
1972
33
Treatment of vasomotor rhinitis with a combined antihistaminic--sympathomimetic preparation. (4402059)
1971
34
Rhinological methods for controlling nasal polyposis and vasomotor rhinitis. (5862571)
1965
35
Interrelation of asthma and vasomotor rhinitis, occurring in patients with housedust atopy. III. In respect to the localization of the symptoms. (13926727)
1962
36
Drug therapy of vasomotor rhinitis and asthma: dibenzheptropine, a valuable adjuvant in the corticoid treatment. (13926728)
1962
37
Interrelation of vasomotor rhinitis and asthma, occurring in patients with housedustatopy. 2. Influence of houses lived in. (13841298)
1960
38
Reflective reactions of the nasal mucosa in vasomotor rhinitis. (13434903)
1957
39
Vasomotor rhinitis. (14388570)
1955
40
Some rhinological syndromes and vasomotor rhinitis. (13311963)
1955
41
Results of treatment of vasomotor rhinitis with hyposensitization. (14397980)
1955
42
Vasomotor rhinitis and bronchial asthma due to Locust Bean Gum dust. (13148984)
1954
43
The vasomotor rhinitis syndrome. (13049699)
1953
44
Chronic vasomotor rhinitis; treatment by submucous diathermic coagulation. (13039666)
1953
45
Vasomotor rhinitis. (14846105)
1950
46
The management of vasomotor rhinitis. (18894292)
1948
47
Vasomotor rhinitis and homeopathic treatment. (18890883)
1948
48
Perennial vasomotor rhinitis; a modern approach to diagnosis and treatment. (20278786)
1947
49
Vasomotor Rhinitis. (20323413)
1945
50
Vasomotor rhinitis. (21011217)
1945

Variations for Vasomotor Rhinitis

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Expression for genes affiliated with Vasomotor Rhinitis

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Expression patterns in normal tissues for genes affiliated with Vasomotor Rhinitis

Search GEO for disease gene expression data for Vasomotor Rhinitis.

Pathways for genes affiliated with Vasomotor Rhinitis

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Pathways related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4IL13, IL10
29.4IL13, IL10
39.3IL10, CD40LG
49.3CD40LG, IL10
59.1IL13, IL10, IL16
6
Show member pathways
8.9IL10, IL13, CD40LG
7
Show member pathways
8.9IL10, IL13, CD40LG
88.9TAC1, IL13, IL10
9
Show member pathways
8.9CD40LG, CALCA, IL10
10
Show member pathways
8.6CD40LG, IL13, IL10, IL16

Compounds for genes affiliated with Vasomotor Rhinitis

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Compounds related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 132)
idCompoundScoreTop Affiliating Genes
1rp6758044 2810.8TAC1, CALCA
2gr 7363244 6110.7CALCA, TAC1
3ltd4449.6TAC1, IL13, VIP
4helospectin449.6TAC1, CALCA, VIP
5guanethidine44 1110.6VIP, CALCA, TAC1
6cromakalim44 2810.5CALCA, VIP, TAC1
7thiorphan44 28 1111.5VIP, CALCA, TAC1
8ng-nitro-l-arginine449.5VIP, TAC1, CALCA
9erythromycin44 2 50 1112.5VIP, IL13, CD40LG
10resiniferatoxin44 2810.5CALCA, TAC1
11phosphoramidon44 1110.5VIP, CALCA, TAC1
12captopril44 61 50 28 1113.5CALCA, TAC1, VIP
13capsaicin44 2810.4VIP, TAC1, CALCA
14salbutamol44 50 28 24 1113.4IL13, IL10, VIP
15prostaglandin f2alpha449.4TAC1, VIP, CALCA
16atropine44 28 1111.4VIP, CALCA, TAC1
17tetrodotoxin44 61 2811.4TAC1, VIP, CALCA
18glucuronoxylomannan449.4CD40LG, IL10
19propranolol44 28 50 24 1113.4TAC1, CALCA, VIP
20enalapril44 50 1111.3VIP, IL10, TAC1
21praziquantel44 1110.3CD40LG, IL10, IL13
22il-12449.3IL10, IL13, CD40LG
23spantide449.3TAC1, VIP
24allergens449.2IL10, CD40LG, IL13
25rituximab44 50 1111.2CD40LG, IL13, IL10
26corticosterone44 61 2411.2IL10, CALCA, VIP
27sodium nitroprusside449.2TAC1, IL13, VIP
28methacholine44 50 1111.2TAC1, VIP, IL13, CALCA
29thalidomide44 50 61 1112.1CD40LG, IL13, IL10
30isoproterenol44 1110.1VIP, IL13, TAC1, CALCA
31epinephrine44 24 1111.0TAC1, VIP, CD40LG, CALCA
32norepinephrine44 24 1110.9CD40LG, TAC1, VIP, CALCA
33lactate448.9CD40LG, CALCA, IL13, VIP
34dopamine44 28 24 1111.7VIP, CALCA, CD40LG, TAC1
35rantes448.6IL16, CD40LG, VIP, IL13, IL10
36indomethacin44 28 61 1111.6CD40LG, VIP, IL13, CALCA, TAC1
37thymidine44 249.6IL16, IL10, VIP, IL13
38acetylcholine44 50 28 24 1112.6IL13, VIP, CALCA, TAC1, CD40LG
39adenylate448.6VIP, CD40LG, TAC1, CALCA, IL13
40glutamate448.5CD40LG, TAC1, CALCA, IL13, VIP
41thyroxine44 249.5IL10, CALCA, CD40LG, VIP, IL13
42cyclosporin a44 28 6110.5IL10, IL13, CALCA, CD40LG, VIP
43theophylline44 28 24 1111.5IL10, IL16, TAC1, IL13, CD40LG
44estrogen448.5VIP, IL13, CALCA, TAC1, CD40LG
45aspartate448.4VIP, IL10, IL13, TAC1, CD40LG
46vegf448.2CD40LG, CALCA, IL16, VIP, IL13, IL10
47nitric oxide44 24 1110.2IL10, IL16, VIP, IL13, CALCA, TAC1
48dexamethasone44 50 28 1111.1IL10, VIP, IL13, TAC1, CD40LG, IL16
49pge2448.0VIP, IL13, CD40LG, CALCA, TAC1, IL10
50histamine44 28 249.7TAC1, CD40LG, CALCA, IL13, IL10, IL16

GO Terms for genes affiliated with Vasomotor Rhinitis

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Cellular components related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:0430258.8VIP, CALCA, TAC1
2extracellular regionGO:0055768.7TAC1, CALCA, IL13, VIP
3extracellular spaceGO:0056157.5CD40LG, TAC1, CALCA, IL13, IL10, IL16

Biological processes related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1leukocyte chemotaxisGO:0305959.7IL10, IL16
2positive regulation of vasodilationGO:0459099.7CALCA, VIP
3positive regulation of ossificationGO:0457789.7TAC1, CALCA
4response to painGO:0482659.7TAC1, CALCA
5regulation of sensory perception of painGO:0519309.6VIP, IL10
6leukocyte cell-cell adhesionGO:0071599.6CD40LG, CALCA
7regulation of blood pressureGO:0082179.4CALCA, TAC1
8B cell proliferationGO:0421009.3CD40LG, IL10
9B cell differentiationGO:0301839.0CD40LG, IL10
10negative regulation of apoptotic processGO:0430669.0CD40LG, IL10, VIP
11cell-cell signalingGO:0072678.7IL10, IL13, CALCA, TAC1
12inflammatory responseGO:0069548.2CD40LG, TAC1, CALCA, IL13, IL10

Molecular functions related to Vasomotor Rhinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.6CALCA, VIP
2cytokine activityGO:0051258.3CD40LG, IL13, IL10, IL16

Products for genes affiliated with Vasomotor Rhinitis

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  • Antibodies
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Sources for Vasomotor Rhinitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet