MCID: VSM001
MIFTS: 34

Vasomotor Rhinitis malady

Categories: Respiratory diseases

Aliases & Classifications for Vasomotor Rhinitis

Aliases & Descriptions for Vasomotor Rhinitis:

Name: Vasomotor Rhinitis 12 14
Rhinitis, Vasomotor 42 69
Rhinitis Vasomotor 52

Classifications:



External Ids:

Disease Ontology 12 DOID:4730
ICD10 33 J30.0
MeSH 42 D012223
NCIt 47 C34988
UMLS 69 C0035460

Summaries for Vasomotor Rhinitis

Disease Ontology : 12 A rhinitis which involves a hypersensitive reaction to various potentially irritating stimuli such as changes in weather, temperature, or barometric pressure, chemical irritants such as smoke, ozone, pollution, perfumes, and aerosol sprays, psychological stress and emotional shocks, medications, alcohol, and spicy food.

MalaCards based summary : Vasomotor Rhinitis, also known as rhinitis, vasomotor, is related to rhinitis and oculogyric crisis. An important gene associated with Vasomotor Rhinitis is VIP (Vasoactive Intestinal Peptide), and among its related pathways/superpathways is G alpha (s) signalling events. The drugs Azelastine and Histamine have been mentioned in the context of this disorder. Affiliated tissues include heart.

Related Diseases for Vasomotor Rhinitis

Diseases related to Vasomotor Rhinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
id Related Disease Score Top Affiliating Genes
1 rhinitis 10.9
2 oculogyric crisis 10.2 TAC1 VIP
3 asthma 10.2
4 female breast nipple and areola cancer 10.2 CD40LG TAC1
5 allergic rhinitis 10.2
6 febrile seizures, familial, 10 10.2 NPS TAC1
7 leber congenital amaurosis 12 10.2 NPS TAC1
8 boutonneuse fever 10.2 NPS TAC1
9 wells-jankovic syndrome 10.1 CALCA VIP
10 childhood endodermal sinus tumor 10.1 NPS TAC1
11 microphthalmia with coloboma 5 10.1 NPS VIP
12 hepatic angiomyolipoma 10.1 NPS TAC1
13 volkmann contracture 10.1 CALCA VIP
14 cockayne syndrome type i 10.1 CALCA VIP
15 spinal stenosis 10.1 CALCA VIP
16 cartilage disease 10.1 CALCA TAC1
17 sweat gland cancer 10.1 TAC1 VIP
18 gemistocytic astrocytoma 10.1 CALCA VIP
19 chronic subinvolution of uterus 10.1 CD40LG IL16
20 keloids 10.1 CALCA VIP
21 dracunculiasis 10.1 CD40LG IL16
22 cerebellar hypoplasia with endosteal sclerosis 10.1 CALCA NPS
23 central nervous system lymphoma 10.1 CALCA TAC1
24 salpingo-oophoritis 10.1 CALCA TAC1
25 uterine ligament serous adenocarcinoma 10.1 CD40LG TAC1
26 infantile hypotonia 10.1 CALCA TAC1
27 corneal ulcer 10.1 CALCA TAC1
28 drug psychosis 10.1 CD40LG TAC1 VIP
29 pseudoinflammatory fundus dystrophy 10.0 RNASE3 TAC1
30 deafness, autosomal dominant 7 10.0 CALCA TAC1
31 ovarian endometrioid cystadenoma 10.0 CALCA NPS
32 heart septal defect 10.0 CD40LG RNASE3
33 central gyrate choroidal dystrophy 10.0 CD40LG RNASE3
34 achilles bursitis 10.0 CD40LG RNASE3
35 dislocation of ear ossicle 10.0 CD40LG RNASE3
36 intravascular angioleiomyoma 10.0 CD40LG RNASE3
37 endobronchial lipoma 10.0 CD40LG RNASE3
38 chronic erythremia 10.0 CD40LG NPS TAC1
39 central nervous system origin vertigo 10.0 CD40LG RNASE3
40 cough variant asthma 10.0 CALCA TAC1 VIP
41 lipid-rich carcinoma 10.0 CALCA TAC1 VIP
42 astrocytoma 10.0 CD40LG RNASE3
43 substance-induced psychosis 10.0 CD40LG NPS TAC1
44 ureteral lymphoma 10.0 CD40LG RNASE3
45 actinic keratosis 9.9 CD40LG RNASE3
46 hemopericardium 9.9 CALCA NPS TAC1
47 autonomic dysfunction 9.9
48 acute dacryoadenitis 9.9 CD40LG RNASE3
49 microcephaly 13, primary, autosomal recessive 9.9 CALCA NPS TAC1
50 uterus interstitial leiomyoma 9.9 CD40LG RNASE3

Graphical network of the top 20 diseases related to Vasomotor Rhinitis:



Diseases related to Vasomotor Rhinitis

Symptoms & Phenotypes for Vasomotor Rhinitis

Drugs & Therapeutics for Vasomotor Rhinitis

Drugs for Vasomotor Rhinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azelastine Approved Phase 4 58581-89-8 2267
2
Histamine Approved, Investigational Phase 4,Phase 3 75614-87-8, 51-45-6 774
3 Analgesics Phase 4
4 Analgesics, Non-Narcotic Phase 4
5 Anti-Allergic Agents Phase 4,Phase 3
6 Anti-Asthmatic Agents Phase 4,Phase 3
7 Anti-Inflammatory Agents Phase 4
8 Anti-Inflammatory Agents, Non-Steroidal Phase 4
9 Antirheumatic Agents Phase 4
10 Autonomic Agents Phase 4,Phase 3
11 Bronchodilator Agents Phase 4,Phase 3
12 Histamine Antagonists Phase 4,Phase 3
13 Histamine H1 Antagonists Phase 4,Phase 3
14 Histamine H1 Antagonists, Non-Sedating Phase 4,Phase 3
15
Histamine Phosphate Phase 4,Phase 3 51-74-1 65513
16 Lipoxygenase Inhibitors Phase 4
17 Neurotransmitter Agents Phase 4,Phase 3
18 Olopatadine Hydrochloride Phase 4
19 Peripheral Nervous System Agents Phase 4,Phase 3
20 Respiratory System Agents Phase 4,Phase 3
21
Cetirizine Approved Phase 3 83881-51-0 2678
22
Ephedrine Approved Phase 3 299-42-3 9294
23
Levocetirizine Approved Phase 3 130018-77-8
24
Pseudoephedrine Approved Phase 3 90-82-4 7028
25
Oxymetazoline Approved Phase 3 1491-59-4 4636
26
Phenylephrine Approved Phase 3 59-42-7 6041
27 Adrenergic Agents Phase 3
28 Central Nervous System Stimulants Phase 3
29 Nasal Decongestants Phase 3
30 Vasoconstrictor Agents Phase 3
31 Adrenergic Agonists Phase 3
32 Adrenergic alpha-Agonists Phase 3
33 Mydriatics Phase 3
34 Protective Agents Phase 3
35
Esomeprazole Approved, Investigational 161796-78-7, 119141-88-7 4594 9579578
36
Menthol Approved 2216-51-5 16666
37 Antacids
38 Anti-Ulcer Agents
39 Gastrointestinal Agents
40
Proton pump inhibitors
41 Pharmaceutical Solutions

Interventional clinical trials:


id Name Status NCT ID Phase
1 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4
2 Study Of Adults And Adolescents With Vasomotor Rhinitis Completed NCT00117325 Phase 3
3 Efficacy/Safety of Pseudoephedrine Plus Levocetirizine Versus Placebo in Patients With Vasomotor Rhinitis Completed NCT01509209 Phase 3
4 Once-Daily Investigational Nasal Spray In Adults And Adolescents With Vasomotor Rhinitis Completed NCT00118703 Phase 3
5 Impact of Acupuncture on Vasomotor Rhinitis Completed NCT00682162 Phase 3
6 Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED) Completed NCT00976209 Phase 3
7 Nasal Physiologic Reactivity of Nonallergic Rhinitics to Cold Air Provocation Completed NCT00415493
8 Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-Blind, Placebo Controlled Trial Completed NCT00745849
9 Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer Completed NCT02338102
10 PBASE System Idiopathic Rhinitis Clinical Investigation Completed NCT01844336

Search NIH Clinical Center for Vasomotor Rhinitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: rhinitis, vasomotor

Genetic Tests for Vasomotor Rhinitis

Anatomical Context for Vasomotor Rhinitis

MalaCards organs/tissues related to Vasomotor Rhinitis:

39
Heart

Publications for Vasomotor Rhinitis

Articles related to Vasomotor Rhinitis:

(show top 50) (show all 196)
id Title Authors Year
1
Severity of nasal obstruction can predict the anxiety status of patients with allergic rhinitis but not patients with vasomotor rhinitis. ( 27277070 )
2016
2
Vitamin D serum levels in children with allergic and vasomotor rhinitis. ( 26512257 )
2015
3
Surgical management of vasomotor rhinitis: A systematic review. ( 25785754 )
2015
4
Therapeutic effectiveness of endoscopic vidian neurectomy for the treatment of vasomotor rhinitis. ( 24433056 )
2014
5
Intranasal capsaicin in management of nonallergic (vasomotor) rhinitis. ( 24941668 )
2014
6
Cytologic alterations in nasal mucosa after sphenopalatine artery ligation in patients with vasomotor rhinitis. ( 22391083 )
2012
7
Sphenopalatine artery ligation with nerve resection in patients with vasomotor rhinitis and polyposis: a prospective, randomized, double-blind investigation. ( 22339556 )
2012
8
Traumatic unilateral vasomotor rhinitis. ( 23288805 )
2012
9
Severe unilateral vasomotor rhinitis: an antecedent sign of vascular compromise? ( 22672492 )
2012
10
Nonallergic rhinopathy (formerlyA known as vasomotor rhinitis). ( 21737036 )
2011
11
Two-week comparison study of olopatadine hydrochloride nasal spray 0.6% versus azelastine hydrochloride nasal spray 0.1% in patients with vasomotor rhinitis. ( 21352639 )
2011
12
Olopatadine 0.6% nasal spray protects from vasomotor challenge in patients with severe vasomotor rhinitis. ( 21819751 )
2011
13
Vasomotor rhinitis. ( 20425499 )
2010
14
Classification of Nonallergic Rhinitis Syndromes With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy. ( 24229372 )
2009
15
Weather/temperature-sensitive vasomotor rhinitis may be refractory to intranasal corticosteroid treatment. ( 19463202 )
2009
16
The treatment of vasomotor rhinitis with intranasal corticosteroids. ( 24228841 )
2009
17
The role of antihistamines in the treatment of vasomotor rhinitis. ( 24228781 )
2009
18
Impact of acupuncture on vasomotor rhinitis: a randomized placebo-controlled pilot study. ( 19388861 )
2009
19
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy Part 1. Introduction. ( 24229340 )
2009
20
Characteristics of nonallergic vasomotor rhinitis. ( 24228982 )
2009
21
Consensus Definition of Nonallergic Rhinopathy, Previously Referred to as Vasomotor Rhinitis, Nonallergic Rhinitis, and/or Idiopathic Rhinitis. ( 24229320 )
2009
22
Consensus Description of Inclusion and Exclusion Criteria for Clinical Studies of Nonallergic Rhinopathy (NAR), Previously Referred to as Vasomotor Rhinitis (VMR), Nonallergic Rhinitis, and/or Idiopathic Rhinitis. ( 24228856 )
2009
23
Nonallergic rhinitis, with a focus on vasomotor rhinitis: clinical importance, differential diagnosis, and effective treatment recommendations. ( 23282951 )
2009
24
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to Be Known henceforth as Nonallergic Rhinopathy: Introduction to Part 2. ( 24228749 )
2009
25
Epidemiology of vasomotor rhinitis. ( 24229078 )
2009
26
Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis. ( 18446592 )
2008
27
[The expression of serum IL-10,12,13,16 in patients with allergic rhinitis and vasomotor rhinitis]. ( 18254318 )
2007
28
CT assessment of the effect of fluticasone propionate aqueous nasal spray treatment on lower turbinate hypertrophy due to vasomotor rhinitis. ( 16308253 )
2006
29
Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis. ( 16680922 )
2006
30
Autonomic nervous system evaluation using heart rate variability parameters in vasomotor rhinitis patients. ( 17049152 )
2006
31
[The roles of three peptides in the pathogenesis of vasomotor rhinitis]. ( 17087112 )
2006
32
Nasal wall compliance in vasomotor rhinitis. ( 16141379 )
2006
33
The effect of intranasal injection of botulinum toxin A on the symptoms of vasomotor rhinitis. ( 16935174 )
2006
34
Immunohistochemical localization of 3-nitrotyrosine in the nasal respiratory mucosa of patients with vasomotor rhinitis. ( 15799577 )
2005
35
Radiofrequency for the treatment of vasomotor rhinitis. ( 16340279 )
2005
36
Open-label evaluation of azelastine nasal spray in patients with seasonal allergic rhinitis and nonallergic vasomotor rhinitis. ( 15899111 )
2005
37
Vasomotor rhinitis. ( 16190503 )
2005
38
Bioavailability and pharmacokinetics of intranasal hydromorphone in patients experiencing vasomotor rhinitis. ( 17523726 )
2004
39
Vasomotor rhinitis update. ( 15167037 )
2004
40
Mechanisms of vasomotor rhinitis. ( 14984550 )
2004
41
Vasomotor rhinitis should not be a wastebasket diagnosis. ( 12759277 )
2003
42
Vasomotor rhinitis is not a wastebasket diagnosis. ( 12759275 )
2003
43
Vasomotor rhinitis remains a true clinical problem. ( 12759276 )
2003
44
Ultrastructural and ultracytochemical study of the human nasal respiratory epithelium in vasomotor rhinitis. ( 14606598 )
2003
45
Autonomic dysfunction, vasomotor rhinitis, and extraesophageal manifestations of gastroesophageal reflux. ( 11997777 )
2002
46
Electrophoretic evaluation of nasal discharge in patients with allergic rhinitis and vasomotor rhinitis. ( 12141770 )
2002
47
Therapy choices beyond antihistamines. Vasomotor rhinitis. ( 12420500 )
2001
48
Vasomotor rhinitis: clinical efficacy of azelastine nasal spray in comparison with placebo. ( 11244365 )
2001
49
Autonomic nervous system evaluation of patients with vasomotor rhinitis. ( 11081594 )
2000
50
Ultracytochemical localization of the NADPH-d activity in the human nasal respiratory mucosa in vasomotor rhinitis. ( 10942142 )
2000

Variations for Vasomotor Rhinitis

Expression for Vasomotor Rhinitis

Search GEO for disease gene expression data for Vasomotor Rhinitis.

Pathways for Vasomotor Rhinitis

Pathways related to Vasomotor Rhinitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.96 CALCA NPS VIP

GO Terms for Vasomotor Rhinitis

Cellular components related to Vasomotor Rhinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 CALCA CD40LG IL16 RNASE3 TAC1
2 extracellular region GO:0005576 9.17 CALCA CD40LG IL16 NPS RNASE3 TAC1

Biological processes related to Vasomotor Rhinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.61 CALCA CD40LG TAC1
2 regulation of blood pressure GO:0008217 9.46 CALCA TAC1
3 cellular response to nerve growth factor stimulus GO:1990090 9.4 CALCA TAC1
4 leukocyte cell-cell adhesion GO:0007159 9.37 CALCA CD40LG
5 response to pain GO:0048265 9.32 CALCA TAC1
6 positive regulation of ossification GO:0045778 9.26 CALCA TAC1
7 positive regulation of synaptic transmission, GABAergic GO:0032230 9.16 NPS TAC1
8 neuropeptide signaling pathway GO:0007218 9.13 CALCA NPS TAC1
9 positive regulation of action potential GO:0045760 8.62 NPS TAC1

Sources for Vasomotor Rhinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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