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MCID: VND001
MIFTS: 47

Vein Disease malady

Categories: Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Vein Disease

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Aliases & Descriptions for Vein Disease:

Name: Vein Disease 12 14
Disorder of Vein 69

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:866
ICD10 33 I82 I87 I87.8
ICD9CM 35 453
SNOMED-CT 64 195435006
UMLS 69 C0155774
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Summaries for Vein Disease

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Disease Ontology : 12 A vascular disease that is located in a vein.

MalaCards based summary : Vein Disease, also known as disorder of vein, is related to venous insufficiency and portal vein thrombosis, and has symptoms including vein pain An important gene associated with Vein Disease is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Ethanol and Heparin have been mentioned in the context of this disorder. Affiliated tissues include a vein, and related phenotypes are homeostasis/metabolism and mortality/aging

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Related Diseases for Vein Disease

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Diseases related to Vein Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
id Related Disease Score Top Affiliating Genes
1 venous insufficiency 10.9
2 portal vein thrombosis 10.6
3 multiple familial trichoepithelioma 10.3 F5 MTHFR
4 congenital insensitivity to pain with severe intellectual disability 10.3 F2 F5
5 absence of innominate vein 10.3 F5 MTHFR
6 nondystrophic myotonia 10.3 ALB F2
7 lubinsky syndrome 10.3 F2 F5 MTHFR
8 supraumbilical midabdominal raphe and facial cavernous hemangiomas 10.3 F2 F5 MTHFR
9 photosensitive epilepsy 10.3 F2 F5 MTHFR
10 scn8a-related epilepsy with encephalopathy 10.3 F2 MTHFR
11 houlston ironton temple syndrome 10.3 F2 F5 MTHFR
12 lymphocytic colitis 10.3 F2 F5 SERPINC1
13 villous adenoma 10.3 F2 F5 MTHFR
14 myosclerosis, congenital 10.3 F5 MTHFR SERPINC1
15 aminoaciduria 10.3 F5 MTHFR
16 neutropenia 10.3 MTHFR PROC
17 stt3a-cdg and stt3b-cdg 10.3 F5 SERPINC1
18 alpha-2-plasmin inhibitor deficiency 10.3 F2 MTHFR SERPINC1
19 porphyria 10.2 F2 MTHFR
20 mental retardation hypotonia skin hyperpigmentation 10.2 F5 PROC SERPINC1
21 ovarian papillary cystadenoma 10.2 ALB F2 SERPINC1
22 childhood type dermatomyositis 10.2 F2 F5 MTHFR
23 miller-dieker lissencephaly syndrome 10.2 F2 PLG SERPINC1
24 vascular erectile tumor 10.2 F2 F5 MTHFR SERPINC1
25 ischemic optic neuropathy 10.2 ALB F2 SERPINC1
26 cleft lip 10.2 F5 MTHFR SERPINC1
27 left-right axis malformations 10.2 F2 F5 MTHFR SERPINC1
28 schwannoma of jugular foramen 10.2 F2 PLG SERPINC1
29 cryptosporidiosis 10.2 F2 F5 MTHFR SERPINC1
30 angular blepharoconjunctivitis 10.2 F2 F5 MTHFR SERPINC1
31 ophthalmia neonatorum 10.2 F2 F5 MTHFR SERPINC1
32 scar contracture 10.2 F2 F5 MTHFR SERPINC1
33 exophthalmic ophthalmoplegia 10.2 ALB F5 SERPINC1
34 sulfhemoglobinemia 10.2 F3 PLG
35 welander distal myopathy 10.2 F5 MTHFR SERPINC1
36 lung cancer 10.2 F5 MTHFR
37 neuronopathy, distal hereditary motor, type iid 10.2 F3 F5 SERPINC1
38 peanut allergy 10.2 F2 PLAT SERPINC1
39 retinal arterial macroaneurysm with supravalvular pulmonic stenosis 10.2 ALB F2 F3
40 hemarthrosis 10.2 F2 F3 PLG
41 fiedler's myocarditis 10.2 ALB F2 SST
42 neurofibroma of the heart 10.2 ALB F5 MTHFR SERPINC1
43 linear scleroderma 10.2 PLAT PLG
44 depressed scar 10.2 ALB F2 F3
45 seminoma 10.2 F2 F3 PLG
46 granulomatous hepatitis 10.2 F2 F3 SERPINC1
47 brain stem cancer 10.2 F2 F3 PLG
48 hendra virus infection 10.2 F2 F3 F5 PROS1
49 vernal conjunctivitis 10.1 ALB MTHFR PLG
50 vulvitis 10.1 AFP F2 F3

Graphical network of the top 20 diseases related to Vein Disease:



Diseases related to Vein Disease
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Symptoms & Phenotypes for Vein Disease

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UMLS symptoms related to Vein Disease:


vein pain

MGI Mouse Phenotypes related to Vein Disease:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.39 ADAM17 AFP ALB EPAS1 EVL F2
2 mortality/aging MP:0010768 10.3 F3 F5 F8 MTHFR PLAT PLG
3 hematopoietic system MP:0005397 10.26 PLAT PLG PROC ADAM17 EPAS1 EVL
4 cardiovascular system MP:0005385 10.24 ADAM17 EPAS1 EVL F2 F3 F5
5 immune system MP:0005387 10.17 ADAM17 EPAS1 EVL F2 F3 F8
6 nervous system MP:0003631 10.07 ADAM17 EPAS1 EVL F2 F3 F5
7 liver/biliary system MP:0005370 10.01 PLG PROC PROS1 SERPINC1 AFP ALB
8 muscle MP:0005369 9.87 ADAM17 ALB EPAS1 F3 PLAT PROC
9 reproductive system MP:0005389 9.76 ADAM17 AFP F2 F8 MTHFR PLAT
10 respiratory system MP:0005388 9.5 ADAM17 EPAS1 F2 F3 PLAT PLG
11 vision/eye MP:0005391 9.17 ADAM17 EPAS1 F3 MTHFR PLAT PLG
Sources

Drugs & Therapeutics for Vein Disease

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Drugs for Vein Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1277)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 64-17-5 702
2
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 772 46507594
3
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
4
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
5
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-02-2 5743
6
Cocaine Approved, Illicit Phase 4,Phase 2,Phase 1 50-36-2 5760 446220
7
Zinc Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 7440-66-6 32051 23994
8
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
9
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 50-28-2 5757 53477783
10
Verapamil Approved Phase 4,Phase 2,Phase 3 52-53-9 2520
11
Daunorubicin Approved Phase 4,Phase 2 20830-81-3 30323
12
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
13
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
14
Cisplatin Approved Phase 4,Phase 2,Phase 3,Phase 1 15663-27-1 84093 441203 2767
15
Idarubicin Approved Phase 4,Phase 2,Phase 1 58957-92-9 42890
16
Cytarabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147-94-4 6253
17
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
18
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
19
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
20
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
21
Nicardipine Approved Phase 4 55985-32-5 4474
22
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
23
Pantoprazole Approved Phase 4 102625-70-7 4679
24
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 73590-58-6 4594
25
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 82410-32-0 3454
26
Nicorandil Approved Phase 4 65141-46-0 47528
27
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 21679-14-1, 75607-67-9 30751
28
Amiodarone Approved, Investigational Phase 4,Phase 3,Phase 2 1951-25-3 2157
29
Warfarin Approved Phase 4,Phase 2,Phase 3,Phase 1 81-81-2 6691 54678486
30
Sorafenib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 284461-73-0 216239 406563
31
Octreotide Approved, Investigational Phase 4,Phase 2,Phase 3 83150-76-9 383414 6400441
32
Vidarabine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 24356-66-9 32326 21704
33
Propranolol Approved, Investigational Phase 4,Phase 3,Phase 2 525-66-6 4946
34
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
35
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-61-7 60961
36
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
37
Terlipressin Approved, Investigational Phase 4,Phase 2 14636-12-5 72081
38
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
39
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3 137-58-6 3676
40
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
41
Tinzaparin Approved Phase 4,Phase 2,Phase 3 9005-49-6, 9041-08-1 25244225
42
Tranylcypromine Approved Phase 4 155-09-9 441233
43
Ketamine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 6740-88-1 3821
44
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 10118-90-8 5281021
45
Sulfadiazine Approved, Vet_approved Phase 4,Phase 3 68-35-9 5215
46
Tranexamic Acid Approved Phase 4,Phase 2,Phase 3,Phase 1 1197-18-8 5526
47
Abatacept Approved Phase 4,Phase 2 332348-12-6 10237
48
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 124-94-7 31307
49
Phenprocoumon Approved Phase 4,Phase 3 435-97-2 9908 54680692
50
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 55-56-1 9552079 2713

Interventional clinical trials:

(show top 50) (show all 5000)
id Name Status NCT ID Phase
1 Compression Aided Management of Edema in Patients With C3 Venous Disease Unknown status NCT00766974 Phase 4
2 ClosureFAST - Radiofrequency Great Saphenous Vein Treatment Unknown status NCT00842296 Phase 4
3 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4
4 Rosuvastatin for Preventing Deep Vein Thrombosis Unknown status NCT01021488 Phase 4
5 Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis Unknown status NCT00640731 Phase 4
6 Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings Unknown status NCT01793194 Phase 4
7 Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy Unknown status NCT02264743 Phase 4
8 Comparison of Stent and Prothesis Bypass in Superficial Femoral Artery Unknown status NCT01147419 Phase 4
9 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
10 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4
11 Global Vascular Effects of Intermittent Pneumatic Compression-Pilot Study Unknown status NCT01064323 Phase 4
12 Second-line Therapy Study of Combined Chemotherapy and Endostar to Patients With Non-Small Cell Lung Cancer(NSCLC) Unknown status NCT00813332 Phase 4
13 Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery Unknown status NCT01171911 Phase 4
14 Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding Unknown status NCT00966355 Phase 4
15 AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy Unknown status NCT02024308 Phase 4
16 Comparing Bivalirudin Versus Heparin/ GP IIB/IIA in Patients Undergoing PCI Unknown status NCT00476944 Phase 4
17 Comparison of Hyperemic Efficacy Between Nicorandil and Adenosine for Fractional Flow Reserve (FFR) Measurement Unknown status NCT01331902 Phase 4
18 Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part II) (DCLI-II) Unknown status NCT01173094 Phase 4
19 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
20 Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia Unknown status NCT01990807 Phase 4
21 Transcatheter Arterial Chemoembolization Combined With Sorafenib for Unresectable Hepatocellular Carcinoma Unknown status NCT01833299 Phase 4
22 Development of an Imaging Biomarker for Hepatic Fibrosis Using Gadoxetate Disodium Unknown status NCT01783314 Phase 4
23 Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections Unknown status NCT01142934 Phase 4
24 Endoscopic Band Ligation (EBL) Versus Propranolol for Primary Prophylaxis of Variceal Bleeding Unknown status NCT00965900 Phase 4
25 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4
26 Use of Bevacizumab to Modulate the Outcomes of Trabeculectomy Surgery Unknown status NCT01229202 Phase 4
27 Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users Unknown status NCT01063426 Phase 4
28 Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism Unknown status NCT02127840 Phase 4
29 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding Unknown status NCT00966121 Phase 4
30 Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment Unknown status NCT00966082 Phase 4
31 A RCT of Oral S-1 in Combination With Sequential HAIC of Oxaliplatin After TACE in Patients With Advanced HCC Unknown status NCT01997957 Phase 4
32 Pulmonary Vein (PV) -Isolation: Arrhythmogenic Vein(s) Versus All Veins Unknown status NCT00605748 Phase 4
33 Quadripolar Leads for the Management of Heart Failure Patients in the Middle East Unknown status NCT02195843 Phase 4
34 EZIO Compared to Central Venous Lines for Emergency Vascular Access Unknown status NCT00785252 Phase 4
35 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4
36 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4
37 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4
38 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4
39 The Contact PVI Study: Use of Tissue Contact Data to Guide Atrial Fibrillation Ablation Unknown status NCT01629056 Phase 4
40 Study of Intravitreal Aflibercept Injection for Persistent CRVO-associated Macular Edema Despite Prior Anti-VEGF Therapy Unknown status NCT01857544 Phase 4
41 A Study Of Pain And Quality Of Life Outcomes In Subjects With a Single Painful Venous Leg Ulcer Treated With Apligraf® Unknown status NCT02011724 Phase 4
42 Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis Unknown status NCT01350206 Phase 4
43 Treatment of Bevacizumab and Triamcinolone in Treatment or Macular Edema Secondary to CRVO Unknown status NCT00566761 Phase 4
44 A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy Unknown status NCT00773539 Phase 4
45 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4
46 Treatment of Plantar Fasciitis With Injection af Platelet-rich Plasma Into the Origin of the Plantar Fascia Unknown status NCT01509274 Phase 4
47 Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery Unknown status NCT01457859 Phase 4
48 Prevention of Venous Thromboembolism in Patients With Acute Primary Intracerebral Hemorrhage Unknown status NCT00699465 Phase 4
49 Cardioversion vs. Catheter Ablation for Persistent Atrial Fibrillation Unknown status NCT00196209 Phase 4
50 The Use of Prostaglandin E1 in Head and Neck Microsurgery Unknown status NCT00733434 Phase 4

Search NIH Clinical Center for Vein Disease

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Genetic Tests for Vein Disease

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Anatomical Context for Vein Disease

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The Foundational Model of Anatomy Ontology organs/tissues related to Vein Disease:

18
A Vein
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Publications for Vein Disease

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Articles related to Vein Disease:

(show all 39)
id Title Authors Year
1
Guidelines of the First International Consensus Conference on Endovenous Thermal Ablation for Varicose Vein Disease - ETAV Consensus Meeting 2012. ( 24534341 )
2014
2
Evaluation of apoptosis in varicose vein disease complicated by superficial vein thrombosis. ( 25007903 )
2014
3
Cost analysis of endovenous catheter ablation versus surgical stripping for treatment of superficial venous insufficiency and varicose vein disease. ( 26992979 )
2014
4
Platelet distribution width and saphenous vein disease in patients after CABG. Association with graft occlusion. ( 22955688 )
2013
5
Molecular characterization and population structure of blackberry vein banding associated virus, new Ampelovirus associated with yellow vein disease. ( 24126200 )
2013
6
One-shot scleroembolization: a new technique for the treatment of varicose veins disease of lower extremities. Preliminary results. ( 23934946 )
2013
7
A review of familial, genetic, and congenital aspects of primary varicose vein disease. ( 22896013 )
2012
8
The hemodynamic paradox as a phenomenon triggering recurrent reflux in varicose vein disease. ( 23997567 )
2012
9
The significance of upper arm cephalic vein disease in vascular access creation. ( 23020965 )
2012
10
Molecular and biological characterization of pepper yellow vein Mali virus (PepYVMV) isolates associated with pepper yellow vein disease in Burkina Faso. ( 21080204 )
2011
11
Increased vein wall apoptosis in varicose vein disease is related to venous hypertension. ( 21262580 )
2011
12
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. ( 21690171 )
2011
13
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. ( 20881312 )
2011
14
Chronic venous insufficiency: current management of varicose vein disease. ( 20336886 )
2010
15
Minimally invasive vein surgery: latest options for vein disease. ( 20506452 )
2010
16
Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation. ( 20632821 )
2010
17
Endovenous laser ablation for the treatment of recurrent varicose vein disease--a single centre experience. ( 20227536 )
2010
18
Further evidence of Mirafiori lettuce big-vein virus but not of Lettuce big-vein associated virus with big-vein disease in lettuce. ( 18944196 )
2008
19
The economics of vein disease. ( 17911565 )
2007
20
Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS). ( 18004259 )
2007
21
A begomovirus associated with Ageratum yellow vein disease in Indonesia: evidence for natural recombination between tomato leaf curl Java virus and Ageratum yellow vein virus-[Java]. ( 17294343 )
2007
22
Changes in the wall of the great saphenous vein at consecutive stages in patients suffering from chronic vein disease of the lower limbs. ( 17985316 )
2007
23
The histopathology of varicose vein disease. ( 17067976 )
2006
24
Selection of saphenous vein conduit in varicose vein disease. ( 16564256 )
2006
25
The DNA beta satellite component associated with ageratum yellow vein disease encodes an essential pathogenicity protein (betaC1). ( 15183051 )
2004
26
Adaptation from whitefly to leafhopper transmission of an autonomously replicating nanovirus-like DNA component associated with ageratum yellow vein disease. ( 11907341 )
2002
27
Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease. ( 12388823 )
2002
28
Pathogenicity of a natural recombinant associated with ageratum yellow vein disease: implications for geminivirus evolution and disease aetiology. ( 11259188 )
2001
29
A unique virus complex causes Ageratum yellow vein disease. ( 10841581 )
2000
30
A nanovirus-like DNA component associated with yellow vein disease of Ageratum conyzoides: evidence for interfamilial recombination between plant DNA viruses. ( 10544139 )
1999
31
Symptomatology of vein disease. ( 7728483 )
1995
32
Unsuspected preexisting saphenous vein disease: an unrecognized cause of vein bypass failure. ( 1728668 )
1992
33
The management of varicose vein disease. ( 287952 )
1979
34
The modern treatment of varicose vein disease. ( 4520459 )
1973
35
Phlebography in varicose vein disease. ( 5014478 )
1972
36
Mesenteric vein disease. ( 13740328 )
1961
37
Yellow-vein disease of citrus and studies of interactions between yellow-vein and other viruses of citrus. ( 13843232 )
1960
38
Pulmonary embolism; its incidence, significance, and relation to antecedent vein disease. ( 18111784 )
1949
39
Pulmonary embolism; its incidence, significance, and relation to antecedent vein disease. ( 18877800 )
1948
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Variations for Vein Disease

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Expression for Vein Disease

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Search GEO for disease gene expression data for Vein Disease.
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Pathways for Vein Disease

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Pathways related to Vein Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 62
Show member pathways
 12.93 ALB F2 F3 F5 F8 PLAT
2
Collagen chain trimerization 62
Show member pathways
 12.52 F2 F3 F5 F8 PROC PROS1
3
Folate Metabolism 1
Show member pathways
 12.1 ALB F2 MTHFR PLAT PLG
4
Formation of Fibrin Clot (Clotting Cascade) 62
Show member pathways
 11.82 F2 F3 F5 F8 PLAT PLG
5
Gamma carboxylation, hypusine formation and arylsulfatase activation 62
Show member pathways
 11.69 F2 PROC PROS1
6
Complement and coagulation cascades 37 1
11.42 F2 F3 F5 F8 PLAT PLG
7
FOXA2 and FOXA3 transcription factor networks 1
11.25 AFP ALB F2
8
A-beta Pathways: Plaque Formation and APP Metabolism 61
11 ADAM17 PLAT PLG
9
Warfarin Pathway, Pharmacodynamics 58
10.67 F2 PROC PROS1
10
Dissolution of Fibrin Clot 62
10.57 PLAT PLG
Sources

GO Terms for Vein Disease

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Cellular components related to Vein Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 9.72 ALB F2 PLG PROS1 SERPINC1
2 platelet alpha granule lumen GO:0031093 9.55 ALB F5 F8 PLG PROS1
3 Golgi lumen GO:0005796 9.54 F2 PROC PROS1
4 endoplasmic reticulum lumen GO:0005788 9.5 AFP ALB F2 F5 F8 PROC
5 extracellular space GO:0005615 9.4 AFP ALB F2 F3 F5 F8
6 extracellular region GO:0005576 10.03 AFP ALB F2 F3 F5 F8

Biological processes related to Vein Disease according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.91 AFP ALB EPAS1 F5 PROC SERPINC1
2 response to hypoxia GO:0001666 9.8 ADAM17 EPAS1 MTHFR PLAT
3 ER to Golgi vesicle-mediated transport GO:0006888 9.8 F2 F5 F8 PROC PROS1
4 platelet activation GO:0030168 9.72 F2 F5 F8
5 platelet degranulation GO:0002576 9.72 ALB F5 F8 PLG PROS1
6 cellular protein metabolic process GO:0044267 9.7 AFP ALB F2 F5 PLG PROC
7 signal peptide processing GO:0006465 9.63 F2 PROC PROS1
8 blood coagulation GO:0007596 9.61 F2 F3 F5 F8 PLAT PLG
9 fibrinolysis GO:0042730 9.56 F2 PLAT PLG PROS1
10 blood coagulation, intrinsic pathway GO:0007597 9.54 F2 F8
11 peptidyl-glutamic acid carboxylation GO:0017187 9.54 F2 PROC PROS1
12 negative regulation of blood coagulation GO:0030195 9.52 PROC PROS1
13 negative regulation of fibrinolysis GO:0051918 9.51 F2 PLG
14 hemostasis GO:0007599 9.23 F2 F3 F5 F8 PLG PROC
15 proteolysis GO:0006508 10.02 ADAM17 F2 F5 F8 PLAT PLG

Molecular functions related to Vein Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.65 ADAM17 F2 PLAT PLG PROC
2 copper ion binding GO:0005507 9.33 ALB F5 F8
3 serine-type peptidase activity GO:0008236 9.26 F2 PLAT PLG PROC
4 serine-type endopeptidase activity GO:0004252 9.17 F2 F3 F5 F8 PLAT PLG
Sources

Sources for Vein Disease

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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